Biology Direct

Papers
(The TQCC of Biology Direct is 6. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-05-01 to 2025-05-01.)
ArticleCitations
USP5 knockdown alleviates lung cancer progression via activating PARP1-mediated mTOR signaling pathway69
DEPTOR attenuates asthma progression by suppressing endoplasmic reticulum stress through SOD153
Long-term longitudinal study on swine VML model53
Circ_0002669 promotes osteosarcoma tumorigenesis through directly binding to MYCBP and sponging miR-889-3p52
Exploring the role of GhN/AINV23: implications for plant growth, development, and drought tolerance44
Moving biology direct towards a new dimension39
Prostatitis, benign prostatic hyperplasia, and prostate cancer: a bidirectional Mendelian randomization study and clinical implications for these patients’ populations35
Functional and structural characterization of the human indolethylamine N-methyltransferase through fluorometric, thermal and computational docking analyses34
Single-cell RNA sequencing reveals the critical role of alternative splicing in cattle testicular spermatagonia34
Wandering about allostery33
NID1 promotes laryngeal cancer stemness via activating WNT pathway31
Equol exerts anti-tumor effects on choriocarcinoma cells by promoting TRIM21-mediated ubiquitination of ANXA229
Deciphering the role of SAMHD1 in endometrial cancer progression29
Neuregulin-4 protects cardiomyocytes against high-glucose-induced ferroptosis via the AMPK/NRF2 signalling pathway28
RGS5 maintaining vascular homeostasis is altered by the tumor microenvironment28
Dualistic role of ZEB1 and ZEB2 in tumor progression28
High-fat diet impairs ferroptosis and promotes cancer invasiveness via downregulating tumor suppressor ACSL4 in lung adenocarcinoma26
Epigenetic mechanism of RBM15 in affecting cisplatin resistance in laryngeal carcinoma cells by regulating ferroptosis25
Lactobacillus reuteri mitigates hepatic ischemia/reperfusion injury by modulating gut microbiota and metabolism through the Nrf2/HO-1 signaling24
The deubiquitinating protein OTUD6B promotes lung adenocarcinoma progression by stabilizing RIPK124
Identification of a prognostic cuproptosis-related signature in hepatocellular carcinoma24
Circulating extracellular vesicles regulate ELAVL1 by delivering miR-133a-3p which affecting NLRP3 mRNA stability inhibiting PANoptosome formation23
Conventional type 1 dendritic cells (cDC1) in cancer immunity22
M2 macrophage-derived exosomal miR-193b-3p promotes progression and glutamine uptake of pancreatic cancer by targeting TRIM6222
ARMCX1 inhibits lung adenocarcinoma progression by recruiting FBXW7 for c-Myc degradation21
ZNF330/NOA36 interacts with HSPA1 and HSPA8 and modulates cell cycle and proliferation in response to heat shock in HEK293 cells19
DTX2 promotes glioma development via regulation of HLTF19
An exploration into the diagnostic capabilities of microRNAs for myocardial infarction using machine learning18
The p53 family member p73 in the regulation of cell stress response18
Biochemical characterization of the feedforward loop between CDK1 and FOXM1 in epidermal stem cells18
Exploring the molecular mechanism of estrogen therapy effectiveness after TCRA in IUA patients at single-cell level16
p53 regulates expression of nuclear envelope components in cancer cells16
Exploring the role of oxidative stress in carotid atherosclerosis: insights from transcriptomic data and single-cell sequencing combined with machine learning15
RCC2 promotes prostate cancer cell proliferation and migration through Hh/GLI1 signaling pathway and cancer stem-like cells15
Correction: High-fat diet impairs ferroptosis and promotes cancer invasiveness via downregulating tumor suppressor ACSL4 in lung adenocarcinoma15
Martin Karplus (1930–2024)15
Identification of druggable targets in acute kidney injury by proteome- and transcriptome-wide Mendelian randomization and bioinformatics analysis14
The RRP9-JUN axis promotes breast cancer progression via the AKT signalling pathway14
FXR1 associates with and degrades PDZK1IP1 and ATOH8 mRNAs and promotes esophageal cancer progression13
Lipidome atlas of p53 mutant variants in pancreatic cancer13
Aged mesenchymal stem cells and inflammation: from pathology to potential therapeutic strategies12
MLL1 promotes placental trophoblast ferroptosis and aggravates preeclampsia symptoms through epigenetic regulation of RBM15/TRIM72/ADAM9 axis12
N6-methyladenosine-mediated SH3BP5-AS1 upregulation promotes GEM chemoresistance in pancreatic cancer by activating the Wnt signaling pathway12
Loss of the centrosomal protein ALMS1 alters lipid metabolism and the regulation of extracellular matrix-related processes12
Machine learning-driven estimation of mutational burden highlights DNAH5 as a prognostic marker in colorectal cancer12
USP44 regulates HEXIM1 stability to inhibit tumorigenesis and metastasis of oral squamous cell carcinoma11
Long-range enhancement of N501Y-endowed mouse infectivity of SARS-CoV-2 by the non-RBD mutations of Ins215KLRS and H655Y11
The role of endothelial cell-related gene COL1A1 in prostate cancer diagnosis and immunotherapy: insights from machine learning and single-cell analysis11
Colon cancer exosome-associated HSP90B1 initiates pre-metastatic niche formation in the liver by polarizing M1 macrophage into M2 phenotype11
LncRNA MIR205HG accelerates cell proliferation, migration and invasion in hepatoblastoma through the activation of MAPK signaling pathway and PI3K/AKT signaling pathway11
Lactobacillus rhamnosus GG ameliorates radiation-induced lung fibrosis via lncRNASNHG17/PTBP1/NICD axis modulation10
Tissue-specific roles of peroxisomes revealed by expression meta-analysis10
RPL35A promotes the progression of cholangiocarcinoma by mediating HSPA8 ubiquitination10
ILC1-derived IFN-γ regulates macrophage activation in colon cancer10
Eraldo Antonini Lectures, 1983–201910
Artificial genetic polymers against human pathologies10
Integrative genomics unveils basement membrane-related diagnostic markers and therapeutic targets in esophageal squamous cell carcinoma10
BMC Caller: a webtool to identify and analyze bacterial microcompartment types in sequence data10
A link between mitotic defects and mitotic catastrophe: detection and cell fate9
miPEP31 alleviates sepsis development by regulating Chi3l1-dependent macrophage polarization9
Mir-338-3p targeting THBS1 attenuates glioma progression by inhibiting the PI3K/Akt pathway9
Shaping root architecture: towards understanding the mechanisms involved in lateral root development9
Single-cell transcriptomic profiling unveils insights into ovarian fibrosis in obese mice9
Dual-labeled nanoparticles based on small extracellular vesicles for tumor detection9
Alpha-actnin-4 (ACTN4) selectively affects the DNA double-strand breaks repair in non-small lung carcinoma cells9
Dysregulation and antimetastatic function of circLRIG1 modulated by miR-214-3p/LRIG1 axis in bladder carcinoma9
Ti3C2 (MXene) nanosheets disrupt spermatogenesis in male mice mediated by the ATM/p53 signaling pathway9
Differential adaptive RNA editing signals between insects and plants revealed by a new measurement termed haplotype diversity9
HOXB4/METTL7B cascade mediates malignant phenotypes of hepatocellular carcinoma through TKT m6A modification8
The oncogenic role and regulatory mechanism of PGK1 in human non-small cell lung cancer8
Mir-421 and mir-550a-1 are potential prognostic markers in esophageal adenocarcinoma8
Understanding p53 tumour suppressor network8
Image-based modeling of vascular organization to evaluate anti-angiogenic therapy8
RARRES1 inhibits hepatocellular carcinoma progression and increases its sensitivity to lenvatinib through interaction with SPINK28
Biological roles of RNA m7G modification and its implications in cancer8
Probing pathways by which rhynchophylline modifies sleep using spatial transcriptomics8
Sorafenib-induced macrophage extracellular traps via ARHGDIG/IL4/PADI4 axis confer drug resistance through inhibiting ferroptosis in hepatocellular carcinoma8
The role of LINC01419 in regulating the cell stemness in lung adenocarcinoma through recruiting EZH2 and regulating FBP1 expression7
Targeting SOX4/PCK2 signaling suppresses neuroendocrine trans-differentiation of castration-resistant prostate cancer7
A functional approach to homeostatic regulation7
miR-155 mediated regulation of PKG1 and its implications on cell invasion, migration, and apoptosis in preeclampsia through NF-κB pathway7
Comprehensive pan-cancer analysis indicates UCHL5 as a novel cancer biomarker and promotes cervical cancer progression through the Wnt signaling pathway6
Integrated Mendelian randomization and single-cell RNA-sequencing analyses identified OAS1 as a novel therapeutic target for erectile dysfunction via targeting fibroblasts6
Quinolinic acid impairs mitophagy promoting microglia senescence and poor healthspan in C. elegans: a mechanism of impaired aging process6
Glucose deprivation-induced disulfidptosis in human nucleus pulposus cells: a novel pathological mechanism of intervertebral disc degeneration6
ADSC-derived exosomes attenuate myocardial infarction injury by promoting miR-205-mediated cardiac angiogenesis6
Integrating machine learning models with multi-omics analysis to decipher the prognostic significance of mitotic catastrophe heterogeneity in bladder cancer6
cGAS-STING targeting offers therapy choice in lung diseases6
Construction of a prognostic model based on disulfidptosis-related genes and identification of CCNA2 as a novel biomarker for hepatocellular carcinoma6
Reprogramming hematopoietic stem cell metabolism in lung cancer: glycolysis, oxidative phosphorylation, and the role of 2-DG6
Correction: Integrated Mendelian randomization and single-cell RNA-sequencing analyses identified OAS1 as a novel therapeutic target for erectile dysfunction via targeting fibroblasts6
Host-mediated RNA editing in viruses6
Transcription factor KLF15 inhibits the proliferation and migration of gastric cancer cells via regulating the TFAP2A-AS1/NISCH axis6
In silico optimization of RNA–protein interactions for CRISPR-Cas13-based antimicrobials6
LncRNA5251 inhibits spermatogenesis via modification of cell-cell junctions6
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