Biology Direct

Article	Citations
Identifying the driver miRNAs with somatic copy number alterations driving dysregulated ceRNA networks in cancers	56
The antipsychotic medications aripiprazole, brexpiprazole and cariprazine are off-target respiratory chain complex I inhibitors	44
Bcl-B: an “unknown” protein of the Bcl-2 family	43
Alpha-actnin-4 (ACTN4) selectively affects the DNA double-strand breaks repair in non-small lung carcinoma cells	43
Exploring the role of GhN/AINV23: implications for plant growth, development, and drought tolerance	34
Evolution of retrocopies in the context of HUSH silencing	32
PSMD3-ILF3 signaling cascade drives lung cancer cell proliferation and migration	32
Phosphodiesterase type 5 inhibitor tadalafil reduces prostatic fibrosis via MiR-3126-3p/FGF9 axis in benign prostatic hyperplasia	29
Nitric oxide-dependent immunosuppressive function of thymus-derived mesenchymal stromal/stem cells	29
Disulfidptosis-associated LncRNA signature predicts prognosis and immune response in kidney renal clear cell carcinoma	25
Dual-labeled nanoparticles based on small extracellular vesicles for tumor detection	25
Mir-338-3p targeting THBS1 attenuates glioma progression by inhibiting the PI3K/Akt pathway	24
Mammalian enabled protein enhances tamoxifen sensitivity of the hormone receptor-positive breast cancer patients by suppressing the AKT signaling pathway	23
Long-term longitudinal study on swine VML model	20
Differential adaptive RNA editing signals between insects and plants revealed by a new measurement termed haplotype diversity	20
Deciphering the impact of MreB on the morphology and pathogenicity of the aquatic pathogen Spiroplasma eriocheiris	19
Inhibition of TRAF6 improves hyperlipidemic acute pancreatitis by alleviating pyroptosis in vitro and in vivo rat models	18
Discovery biomarker to optimize obeticholic acid treatment for non-alcoholic fatty liver disease	18
GPR137 inactivates Hippo signaling to promote gastric cancer cell malignancy	17
Kruppel-like factor 13 acts as a tumor suppressor in thyroid carcinoma by downregulating IFIT1	17
p53-driven lipidome influences non-cell-autonomous lysophospholipids in pancreatic cancer	16
Understanding p53 tumour suppressor network	16
C-MYC-activated lncRNA SNHG20 accelerates the proliferation of diffuse large B cell lymphoma via USP14-mediated deubiquitination of β-catenin	16
Ti3C2 (MXene) nanosheets disrupt spermatogenesis in male mice mediated by the ATM/p53 signaling pathway	15
USP5 knockdown alleviates lung cancer progression via activating PARP1-mediated mTOR signaling pathway	15

MiR-19b-3p regulated by BC002059/ABHD10 axis promotes cell apoptosis in myocardial infarction	14
Circ_0002669 promotes osteosarcoma tumorigenesis through directly binding to MYCBP and sponging miR-889-3p	14
Long-read assembly of major histocompatibility complex and killer cell immunoglobulin-like receptor genome regions in cynomolgus macaque	14
Novel crossover and recombination hotspots massively spread across primate genomes	14
Antitumoral effects of Bortezomib in malignant mesothelioma: evidence of mild endoplasmic reticulum stress in vitro and activation of T cell response in vivo	13
Enhanced itaconic acid secretion from macrophages mediates the protection of mesenchymal stem cell-derived exosomes on lipopolysaccharide-induced acute lung injury mice	13
Exosomes containing circSCP2 in colorectal cancer promote metastasis via sponging miR-92a-1-5p and interacting with PTBP1 to stabilize IGF2BP1	13
N6-methyladenosine methyltransferase KIAA1429 promoted ovarian cancer aerobic glycolysis and progression through enhancing ENO1 expression	12
m6A-mediated upregulation of LINC01003 regulates cell migration by targeting the CAV1/FAK signaling pathway in glioma	12
Long non-coding RNA SNHG8 enhances triple-negative breast cancer cell proliferation and migration by regulating the miR-335-5p/PYGO2 axis	12
Downregulation of amphiregulin improves cardiac hypertrophy via attenuating oxidative stress and apoptosis	12
DEPTOR attenuates asthma progression by suppressing endoplasmic reticulum stress through SOD1	11
miPEP31 alleviates sepsis development by regulating Chi3l1-dependent macrophage polarization	11
Discovery of potential natural therapeutics targeting cell wall biosynthesis in multidrug-resistant Enterococcus faecalis: a computational perspective	11
Rab32 uses its effector reticulon 3L to trigger autophagic degradation of mitochondria-associated membrane (MAM) proteins	10
Human lung cancer-derived mesenchymal stem cells promote tumor growth and immunosuppression	10
Multiplex antimicrobial activities of the self-assembled amphiphilic polypeptide β nanofiber KF-5 against vaginal pathogens	10
MiR-31-5p regulates the neuroinflammatory response via TRAF6 in neuropathic pain	9
Integrating multi-layered biological priors to improve genomic prediction accuracy in beef cattle	9
Biological roles of RNA m7G modification and its implications in cancer	9
Long-term administration of Western diet induced metabolic syndrome in mice and causes cardiac microvascular dysfunction, cardiomyocyte mitochondrial damage, and cardiac remodeling involving caveolae	9
Boanmycin overcomes bortezomib resistance by inducing DNA damage and endoplasmic reticulum functional impairment in multiple myeloma	9
Migrasomes, new vescicles as Hansel and Gretel white pebbles?	9
LINC01094 promotes gastric cancer through dual targeting of CDKN1A by directly binding RBMS2 and HDAC1	9
Comprehensive analysis of mitochondria-related genes indicates that PPP2R2B is a novel biomarker and promotes the progression of bladder cancer via Wnt signaling pathway	8
Bi-targeting of thioredoxin 1 and telomerase by thiotert promotes cell death of myelodysplastic syndromes and lymphoma	8
Soft X-ray tomography analysis of mitochondria dynamics in Saccharomyces cerevisiae	8
Risk assessment of transgender people: implementation of a demasculinizing–feminizing rodent model including the evaluation of thyroid homeostasis	8
A myeloid leukemia factor homolog is involved in tolerance to stresses and stress-induced protein metabolism in Giardia lamblia	7
Dynamic expression of IGFBP3 modulate dual actions of mineralization micro-environment during tooth development via Wnt/beta-catenin signaling pathway	7
RGS5 maintaining vascular homeostasis is altered by the tumor microenvironment	7
Analysis of state 1—state 2 transitions by genome editing and complementation reveals a quenching component independent from the formation of PSI-LHCI-LHCII supercomplex in Arabidopsis thaliana	7
Depletion of LONP2 unmasks differential requirements for peroxisomal function between cell types and in cholesterol metabolism	7
Efficient DNA-free co-targeting of nuclear genes in Chlamydomonas reinhardtii	6
Sorafenib-induced macrophage extracellular traps via ARHGDIG/IL4/PADI4 axis confer drug resistance through inhibiting ferroptosis in hepatocellular carcinoma	6
NID1 promotes laryngeal cancer stemness via activating WNT pathway	6
Analysis of lineage-specific protein family variability in prokaryotes combined with evolutionary reconstructions	6
Deciphering the role of SAMHD1 in endometrial cancer progression	6
miR-630 as a therapeutic target in pancreatic cancer stem cells: modulation of the PRKCI-Hedgehog signaling axis	6
LINC00909 up-regulates pluripotency factors and promotes cancer stemness and metastasis in pancreatic ductal adenocarcinoma by targeting SMAD4	6
Identification of a prognostic cuproptosis-related signature in hepatocellular carcinoma	5
Probing pathways by which rhynchophylline modifies sleep using spatial transcriptomics	5
UBE2N promotes cell viability and glycolysis by promoting Axin1 ubiquitination in prostate cancer cells	5
PLAU promotes growth and attenuates cisplatin chemosensitivity in ARID1A-depleted non-small cell lung cancer through interaction with TM4SF1	5
Vemurafenib induces senescence in acute myeloid leukemia and myelodysplastic syndrome by activating the HIPPO signaling pathway: implications for potential targeted therapy	5
Mir-421 and mir-550a-1 are potential prognostic markers in esophageal adenocarcinoma	5
The oncogenic role and regulatory mechanism of PGK1 in human non-small cell lung cancer	5
Single-cell RNA sequencing reveals the critical role of alternative splicing in cattle testicular spermatagonia	5
Identification of RNA reads encoding different channels in isolated rat ventricular myocytes and the effect of cell stretching on L-type Ca2+current	5
Matrix Metalloproteinase-9 is associated with tumor microenvironment remodeling of bladder cancer	4

Common pathways and functional profiles reveal underlying patterns in Breast, Kidney and Lung cancers	4
NSUN2 relies on ALYREF to regulate Nrf2-mediated oxidative stress and alleviate Dox-induced liver injury	4
Study on the mechanism of LOXL1-AS1/miR-3614-5p/YY1 signal axis in the malignant phenotype regulation of hepatocellular carcinoma	4
USP24-dependent stabilization of Runx2 recruits a p300/NCOA3 complex to transactivate ADAMTS genes and promote degeneration of intervertebral disc in chronic inflammation mice	4
RARRES1 inhibits hepatocellular carcinoma progression and increases its sensitivity to lenvatinib through interaction with SPINK2	4
NUAK2 and RCan2 participate in the p53 mutant pro-tumorigenic network	4
An integrative in-silico analysis discloses a novel molecular subset of colorectal cancer possibly eligible for immune checkpoint immunotherapy	4
Principles and biological concepts of heredity before Mendel	4
Single-molecule long-read methylation profiling reveals regional DNA methylation regulated by Elongator Complex Subunit 2 in Arabidopsis roots experiencing spaceflight	4
Polymorphism on human aromatase affects protein dynamics and substrate binding: spectroscopic evidence	4
Perilipin 5 deficiency aggravates cardiac hypertrophy by stimulating lactate production in leptin-deficient mice	4
Circ_MAPK9 promotes STAT3 and LDHA expression by silencing miR-642b-3p and affects the progression of hepatocellular carcinoma	4
Neuregulin-4 protects cardiomyocytes against high-glucose-induced ferroptosis via the AMPK/NRF2 signalling pathway	4
Prostatitis, benign prostatic hyperplasia, and prostate cancer: a bidirectional Mendelian randomization study and clinical implications for these patients’ populations	3
ACSM5 inhibits ligamentum flavum hypertrophy by regulating lipid accumulation mediated by FABP4/PPAR signaling pathway	3
Wandering about allostery	3
TRIM47 drives gastric cancer cell proliferation and invasion by regulating CYLD protein stability	3
LncRNA NORFA promotes the synthesis of estradiol and inhibits the apoptosis of sow ovarian granulosa cells through SF-1/CYP11A1 axis	3
CircHIF1A induces cetuximab resistance in colorectal cancer by promoting HIF1α-mediated glycometabolism alteration	3
Equol exerts anti-tumor effects on choriocarcinoma cells by promoting TRIM21-mediated ubiquitination of ANXA2	3
Epigenetic mechanism of RBM15 in affecting cisplatin resistance in laryngeal carcinoma cells by regulating ferroptosis	3
Characterization of the symmetrical benzimidazole twin drug TL1228: the role as viral entry inhibitor for fighting COVID-19	3
The periosteum: a simple tissue with many faces, with special reference to the antler-lineage periostea	3
Image-based modeling of vascular organization to evaluate anti-angiogenic therapy	3
The role of adipose tissue-derived stromal cells, macrophages and bioscaffolds in cutaneous wound repair	3
ZFP64 drives glycolysis-mediated stem cell-like properties and tumorigenesis in breast cancer	3
N6-methyladenosine regulators in hepatocellular carcinoma: investigating the precise definition and clinical applications of biomarkers	3
ADAMTS4 exacerbates lung cancer progression via regulating c-Myc protein stability and activating MAPK signaling pathway	3
Transcription factor KLF15 inhibits the proliferation and migration of gastric cancer cells via regulating the TFAP2A-AS1/NISCH axis	2
PHF5A promotes esophageal squamous cell carcinoma progression via stabilizing VEGFA	2
ZNF330/NOA36 interacts with HSPA1 and HSPA8 and modulates cell cycle and proliferation in response to heat shock in HEK293 cells	2
M2 macrophage-derived exosomes promote angiogenesis and improve cardiac function after myocardial infarction	2
DTX2 promotes glioma development via regulation of HLTF	2
A glutamine metabolish-associated prognostic model to predict prognosis and therapeutic responses of hepatocellular carcinoma	2
Regulating ferroptosis by non-coding RNAs in hepatocellular carcinoma	2
Lysine-specific methyltransferase Set7/9 in stemness, differentiation, and development	2
The role of LINC01419 in regulating the cell stemness in lung adenocarcinoma through recruiting EZH2 and regulating FBP1 expression	2
Targeting SOX4/PCK2 signaling suppresses neuroendocrine trans-differentiation of castration-resistant prostate cancer	2
Alamandine alleviated heart failure and fibrosis in myocardial infarction mice	2
Hypoxia-induced activation of HIF-1alpha/IL-1beta axis in microglia promotes glioma progression via NF-κB-mediated upregulation of heparanase expression	2
YY1 mediated DCUN1D5 transcriptional activation promotes triple-negative breast cancer progression by targeting FN1/PI3K/AKT pathway	2
High-fat diet impairs ferroptosis and promotes cancer invasiveness via downregulating tumor suppressor ACSL4 in lung adenocarcinoma	2
TM4SF1 upregulates MYH9 to activate the NOTCH pathway to promote cancer stemness and lenvatinib resistance in HCC	2
Correction: Comprehensive analysis of mitochondria-related genes indicates that PPP2R2B is a novel biomarker and promotes the progression of bladder cancer via Wnt signaling pathway	2
Lactobacillus reuteri mitigates hepatic ischemia/reperfusion injury by modulating gut microbiota and metabolism through the Nrf2/HO-1 signaling	2
The deubiquitinating protein OTUD6B promotes lung adenocarcinoma progression by stabilizing RIPK1	2
H19X-encoded microRNAs induced by IL-4 in adipocyte precursors regulate proliferation to facilitate differentiation	2
Conventional type 1 dendritic cells (cDC1) in cancer immunity	2
A functional reference map of the RNF8 interactome in cancer	2
Phylogenomic analysis of the diversity of graspetides and proteins involved in their biosynthesis	2
YTHDF2 promotes anaplastic thyroid cancer progression by activating the DDIT4/AKT/mTOR signaling pathway	2
Identification of novel snoRNA-based biomarkers for clear cell renal cell carcinoma from urine-derived extracellular vesicles	2
Glucose deprivation-induced disulfidptosis in human nucleus pulposus cells: a novel pathological mechanism of intervertebral disc degeneration	2
Pharmacological inhibition of mTORC1 reduces neural death and damage volume after MCAO by modulating microglial reactivity	2
Regulation of renal ischemia-reperfusion injury and tubular epithelial cell ferroptosis by pparγ m6a methylation: mechanisms and therapeutic implications	1
RNF19A inhibits bladder cancer progression by regulating ILK ubiquitination and inactivating the AKT/mTOR signalling pathway	1
Characterization of gut microbiota dynamics in an Alzheimer’s disease mouse model through clade-specific marker-based analysis of shotgun metagenomic data	1
Bone metabolism associated with annual antler regeneration: a deer insight into osteoporosis reversal	1
Integrative analysis of the salt stress response in cyanobacteria	1
LINC00858 stabilizes RAN expression and promotes metastasis of gastric cancer	1
Coordinating energy metabolism and signaling pathways in epithelial self-renewal and differentiation	1
hsa_circ_0020093 suppresses ovarian cancer progression by modulating LRPPRC activity and miR-107/LATS2 signaling	1
CircRNA_15430 reduced by Helicobacter pylori infection and suppressed gastric cancer progression via miR-382-5p/ZCCHC14 axis	1
Biochemical characterization of the feedforward loop between CDK1 and FOXM1 in epidermal stem cells	1
Valentina Tassinari, the legacy of a young scientist	1
MIR194-2HG, a miRNA host gene activated by HNF4A, inhibits gastric cancer by regulating microRNA biogenesis	1
Correction: Risk assessment of transgender people: implementation of a demasculinizing–feminizing rodent model including the evaluation of thyroid homeostasis	1
The p53 family member p73 in the regulation of cell stress response	1
BRD4 sustains p63 transcriptional program in keratinocytes	1
Immune-response gene 1 deficiency aggravates inflammation-triggered cardiac dysfunction by inducing M1 macrophage polarization and aggravating Ly6Chigh monocyte recruitment	1
Gastrin-related circRNA_0017065 promotes the proliferation and metastasis of colorectal cancer through the miR-3174/RBFOX2 axis	1
A genome-wide search of Toll/Interleukin-1 receptor (TIR) domain-containing adapter molecule (TICAM) and their evolutionary divergence from other TIR domain containing proteins	1
MAP7D3, a novel prognostic marker for triple-negative breast cancer, drives cell invasiveness and cancer-initiating cell properties to promote metastatic progression	1
miR-210 is essential to retinal homeostasis in fruit flies and mice	1
The impact of androgen-induced translation in modulating androgen receptor activity	1
Integrated machine learning reveals the role of tryptophan metabolism in clear cell renal cell carcinoma and its association with patient prognosis	1
ALKBH5 activates CEP55 transcription through m6A demethylation in FOXP2 mRNA and expedites cell cycle entry and EMT in ovarian cancer	1
miR-155 mediated regulation of PKG1 and its implications on cell invasion, migration, and apoptosis in preeclampsia through NF-κB pathway	1
ARMCX1 inhibits lung adenocarcinoma progression by recruiting FBXW7 for c-Myc degradation	1
Deciphering MOSPD1’s impact on breast cancer progression and therapeutic response	1

Silencing LINC00987 ameliorates adriamycin resistance of acute myeloid leukemia via miR-4458/HMGA2 axis	1
A comprehensive molecular characterization of a claudin-low luminal B breast tumor	1
M2 macrophage-derived exosomal miR-193b-3p promotes progression and glutamine uptake of pancreatic cancer by targeting TRIM62	1
Long non-coding RNAs affecting cell metabolism in cancer	1