Biology Direct

Article	Citations
Exploring the role of GhN/AINV23: implications for plant growth, development, and drought tolerance	86
USP5 knockdown alleviates lung cancer progression via activating PARP1-mediated mTOR signaling pathway	63
DEPTOR attenuates asthma progression by suppressing endoplasmic reticulum stress through SOD1	60
MINPP1 promotes ferroptosis in HBV-related hepatocellular carcinoma by regulating CTSB K33-linked deubiquitination via ZRANB1	48
Organelle-specific regulation of ferroptosis	47
ELOVL1 promotes the progression of intrahepatic cholangiocarcinoma by enhancing endoplasmic reticulum stress and the PI3K/AKT/mTOR signaling pathway	46
Long-term longitudinal study on swine VML model	42
Single-cell transcriptomic analysis deciphers heterogeneity and transcriptional regulatory programs of sepsis with different prognosis	41
Circ_0002669 promotes osteosarcoma tumorigenesis through directly binding to MYCBP and sponging miR-889-3p	38
Moving biology direct towards a new dimension	38
Wandering about allostery	37
Functional and structural characterization of the human indolethylamine N-methyltransferase through fluorometric, thermal and computational docking analyses	36
Equol exerts anti-tumor effects on choriocarcinoma cells by promoting TRIM21-mediated ubiquitination of ANXA2	35
SIRT1 haploinsufficiency recapitulates age-associated subfertility through sperm α-tubulin hyperacetylation	34
Identification of a prognostic cuproptosis-related signature in hepatocellular carcinoma	33
Deciphering the role of SAMHD1 in endometrial cancer progression	32
A hybrid ST-ViT–driven multimodal architecture combining spatiotemporal MRI patterns and radiomic features for enhanced prediction of pCR in neoadjuvant breast cancer therapy	29
Molecular mechanisms of efferocytosis imbalance in the idiopathic pulmonary fibrosis microenvironment: from gene screening to dynamic regulation analysis	28
Neuregulin-4 protects cardiomyocytes against high-glucose-induced ferroptosis via the AMPK/NRF2 signalling pathway	28
Prostatitis, benign prostatic hyperplasia, and prostate cancer: a bidirectional Mendelian randomization study and clinical implications for these patients’ populations	27
Comparative analysis of human Mesenchymal Stromal Cells from Adipose Tissue and Dental Pulp: phenotypic characterization and secretome profiling	27
Dualistic role of ZEB1 and ZEB2 in tumor progression	27
Epigenetic mechanism of RBM15 in affecting cisplatin resistance in laryngeal carcinoma cells by regulating ferroptosis	26
Single-cell RNA sequencing reveals the critical role of alternative splicing in cattle testicular spermatagonia	25
NID1 promotes laryngeal cancer stemness via activating WNT pathway	25

Effect of pesticides on breast cancer tumor	25
Radix Rehmanniae Preparata polysaccharide promoted zebrafish heart regeneration by activating the IFN-γ/NF-κB signaling axis	23
ARMCX1 inhibits lung adenocarcinoma progression by recruiting FBXW7 for c-Myc degradation	23
RGS5 maintaining vascular homeostasis is altered by the tumor microenvironment	23
Exploring fetal skeletal alterations induced by gold nanoparticles in mice confirmed by laser speckle imaging and LIBS approach	23
Attenuation of Wnt signaling by miR-27a-5p–GFPT2–HBP axis via metabolic reprogramming in colorectal cancer	22
Biochemical characterization of the feedforward loop between CDK1 and FOXM1 in epidermal stem cells	21
The deubiquitinating protein OTUD6B promotes lung adenocarcinoma progression by stabilizing RIPK1	21
The MST4–14-3-3ζ complex promotes pancreatic cancer by activating YAP	20
Lactobacillus reuteri mitigates hepatic ischemia/reperfusion injury by modulating gut microbiota and metabolism through the Nrf2/HO-1 signaling	19
M2 macrophage-derived exosomal miR-193b-3p promotes progression and glutamine uptake of pancreatic cancer by targeting TRIM62	19
Transcutaneous auricular vagus nerve stimulation alleviates chronic heart failure by targeting cathepsin K/p53-mediated ferroptosis	19
Circulating extracellular vesicles regulate ELAVL1 by delivering miR-133a-3p which affecting NLRP3 mRNA stability inhibiting PANoptosome formation	19
Single-cell analysis reveals that NRG1/3–ERBB4 signaling affects metabolic reprogramming and immune escape in Wilms tumor	19
Conventional type 1 dendritic cells (cDC1) in cancer immunity	18
Activation of the TGR5/cAMP/PKA/CREB axis in cholangiocytes mediates epithelial-mesenchymal transition and fibrosis in hepatolithiasis	18
ZNF330/NOA36 interacts with HSPA1 and HSPA8 and modulates cell cycle and proliferation in response to heat shock in HEK293 cells	18
An exploration into the diagnostic capabilities of microRNAs for myocardial infarction using machine learning	18
Pyrroloquinoline quinone protects heat-stressed porcine oocytes and improves early embryonic development via maintaining mitochondrial integrity and redox homeostasis	18
DTX2 promotes glioma development via regulation of HLTF	18
Restriction-modification systems and prophages drive genomic diversification in Priestia megaterium	18
Lipidome atlas of p53 mutant variants in pancreatic cancer	17
Martin Karplus (1930–2024)	17
Exploring the molecular mechanism of estrogen therapy effectiveness after TCRA in IUA patients at single-cell level	17
Loss of the centrosomal protein ALMS1 alters lipid metabolism and the regulation of extracellular matrix-related processes	17
The role of SH3RF2 in lung squamous cell carcinoma and M2 polarization: insights into LZTS2 ubiquitination	17
Correction: Affibodies as valuable tool to prevent β2m aggregation under lysosomal-like conditions	17
A novel synergistic action of phage vB_PaeP_GZMU_A1002 with allicin against carbapenem-resistant Pseudomonas aeruginosa	17
Correction: High-fat diet impairs ferroptosis and promotes cancer invasiveness via downregulating tumor suppressor ACSL4 in lung adenocarcinoma	16
FXR1 associates with and degrades PDZK1IP1 and ATOH8 mRNAs and promotes esophageal cancer progression	16
Spatiotemporal dynamics of neuronal subtypes and their interactions with glia following intracortical electrode implantation	16
Exploring the role of oxidative stress in carotid atherosclerosis: insights from transcriptomic data and single-cell sequencing combined with machine learning	16
Identification of druggable targets in acute kidney injury by proteome- and transcriptome-wide Mendelian randomization and bioinformatics analysis	15
Integrative transcriptomic profiling reveals NK cell exhaustion–associated prognostic genes and identifies CSF1 as a key immunoregulatory target in hepatocellular carcinoma	15
The RRP9-JUN axis promotes breast cancer progression via the AKT signalling pathway	15
Aged mesenchymal stem cells and inflammation: from pathology to potential therapeutic strategies	15
PHGDH mediated serine biosynthesis metabolism suppresses vascular calcification	15
Transcription factor IRF1 modulates HDAC1 and PANoptosis to regulate preeclampsia progression	15
N6-methyladenosine-mediated SH3BP5-AS1 upregulation promotes GEM chemoresistance in pancreatic cancer by activating the Wnt signaling pathway	15
S100A4 triggeres the pyroptosis of vsmcs: association with mitochondrial damage, impaired mitophagy, and Ca2+ dysregulation	15
Incomplete radiofrequency ablation may elicit pro-oncogenic effects in thyroid cancer cells in a xenograft mouse model	15
RCC2 promotes prostate cancer cell proliferation and migration through Hh/GLI1 signaling pathway and cancer stem-like cells	15
MLL1 promotes placental trophoblast ferroptosis and aggravates preeclampsia symptoms through epigenetic regulation of RBM15/TRIM72/ADAM9 axis	14
Machine learning-driven estimation of mutational burden highlights DNAH5 as a prognostic marker in colorectal cancer	14
Long-range enhancement of N501Y-endowed mouse infectivity of SARS-CoV-2 by the non-RBD mutations of Ins215KLRS and H655Y	14
A multi-omics exploration of PPARG activation in colon cancer: kinases featuring a PPRE sequence within regulatory regions	14
Prenatal bisphenol A exposure perturbs sex-dependent transcriptomic regionalization of autism-associated genes in the developing brain	14
Dysregulated competitive splicing between circular and linear RNAs characterizes hepatocellular carcinoma tumorigenesis and recurrence	14
Plasma membrane calcium ATPases and cerebellar pathology: what’s the role in the ataxia?	14
p53 regulates expression of nuclear envelope components in cancer cells	14

RPL35A promotes the progression of cholangiocarcinoma by mediating HSPA8 ubiquitination	14
The role of endothelial cell-related gene COL1A1 in prostate cancer diagnosis and immunotherapy: insights from machine learning and single-cell analysis	14
USP44 regulates HEXIM1 stability to inhibit tumorigenesis and metastasis of oral squamous cell carcinoma	14
Colon cancer exosome-associated HSP90B1 initiates pre-metastatic niche formation in the liver by polarizing M1 macrophage into M2 phenotype	13
Eraldo Antonini Lectures, 1983–2019	13
Tissue-specific roles of peroxisomes revealed by expression meta-analysis	13
Artificial genetic polymers against human pathologies	13
In vitro synergistic effect of AXL, FAK and ErbB receptors inhibitors for head and neck cancer	13
ILC1-derived IFN-γ regulates macrophage activation in colon cancer	13
CLOCK-mediated acetylation of NF-κB p65 drives immune evasion in breast cancer	13
Indispensable role of AcrEF in modulating Salmonella virulence and disrupting host tight junctions to facilitate paracellular entry and invasion	13
Dysregulation and antimetastatic function of circLRIG1 modulated by miR-214-3p/LRIG1 axis in bladder carcinoma	12
Shaping root architecture: towards understanding the mechanisms involved in lateral root development	12
Integrative genomics unveils basement membrane-related diagnostic markers and therapeutic targets in esophageal squamous cell carcinoma	12
MEF2A activates the ZDHHC20/NF-κB pathway to inhibit doxorubicin sensitivity and promote the malignant progression of acute myeloid leukemia	12
CircPTP4A2 (hsa_circ_0007364) facilitates non-small cell lung cancer progression by regulating miR-127-5p/SMC3	12
Single-cell transcriptomic profiling unveils insights into ovarian fibrosis in obese mice	12
Lactobacillus rhamnosus GG ameliorates radiation-induced lung fibrosis via lncRNASNHG17/PTBP1/NICD axis modulation	12
ETV4 promotes colorectal cancer progression through SLC7A11-mediated ferroptosis inhibition	12
Autophagy inhibition potentiates anti-cancer activity of Sunitinib in kidney cancer cells	12
miPEP31 alleviates sepsis development by regulating Chi3l1-dependent macrophage polarization	11
Ti3C2 (MXene) nanosheets disrupt spermatogenesis in male mice mediated by the ATM/p53 signaling pathway	11
Dual-labeled nanoparticles based on small extracellular vesicles for tumor detection	11
Platelet-activating factor induces ferroptosis by binding to ATF3 and inhibiting the SLC7A11/GPX4 axis to suppress the progression of endometrial carcinoma	11
Mir-338-3p targeting THBS1 attenuates glioma progression by inhibiting the PI3K/Akt pathway	11
Alpha-actnin-4 (ACTN4) selectively affects the DNA double-strand breaks repair in non-small lung carcinoma cells	11
Biological roles of RNA m7G modification and its implications in cancer	11
Integrative satellitomics reveals distinct patterns of organization, transcription and evolution of satellite DNAs in Tenebrio molitor	11
SPI1 upregulated LILRB2 to enhance the immunosuppressive phenotype of LPS-tolerant macrophages by inhibiting TLR8-mediated MyD88/NF-κB signaling	11
Differential adaptive RNA editing signals between insects and plants revealed by a new measurement termed haplotype diversity	11
Inhibition of circZFX suppresses malignant phenotypes in cholangiocarcinoma via the miR-654-3p/HDGF and YAP1 signaling activation	11
HOXB4/METTL7B cascade mediates malignant phenotypes of hepatocellular carcinoma through TKT m6A modification	10
Mir-421 and mir-550a-1 are potential prognostic markers in esophageal adenocarcinoma	10
Image-based modeling of vascular organization to evaluate anti-angiogenic therapy	10
Reprogramming hematopoietic stem cell metabolism in lung cancer: glycolysis, oxidative phosphorylation, and the role of 2-DG	10
The role of LINC01419 in regulating the cell stemness in lung adenocarcinoma through recruiting EZH2 and regulating FBP1 expression	10
Glucose deprivation-induced disulfidptosis in human nucleus pulposus cells: a novel pathological mechanism of intervertebral disc degeneration	10
Probing pathways by which rhynchophylline modifies sleep using spatial transcriptomics	10
Estrogen receptor alpha dynamics and plasticity during endocrine resistance	10
Sorafenib-induced macrophage extracellular traps via ARHGDIG/IL4/PADI4 axis confer drug resistance through inhibiting ferroptosis in hepatocellular carcinoma	10
Integrated Mendelian randomization and single-cell RNA-sequencing analyses identified OAS1 as a novel therapeutic target for erectile dysfunction via targeting fibroblasts	10
Targeting SOX4/PCK2 signaling suppresses neuroendocrine trans-differentiation of castration-resistant prostate cancer	10
The oncogenic role and regulatory mechanism of PGK1 in human non-small cell lung cancer	10
RARRES1 inhibits hepatocellular carcinoma progression and increases its sensitivity to lenvatinib through interaction with SPINK2	10
A dopaminergic projection from the ventral tegmental area to the dorsal raphe nucleus critically regulates propofol anesthesia in mice	10
Inhibition of PRC1 elicits immunogenic cell death by triggering ROS-dependent ER stress in colorectal cancer via the Wnt/β-catenin signaling pathway	10
Necroptosis-driven T cell activation promotes IL-6-mediated PD-L1 upregulation in cholangiocarcinoma cells: IL-6 gene signature as a biomarker for chemo-immunotherapy response	10
Revealing FPR1 as a potential pathogenic biomarker for aortic dissection based on Mendelian randomization, single-cell transcriptome and clinical data analysis	10
HMGA1 promotes the progression of lung adenocarcinoma through the STAT1-mediated transcriptional activation of DDAH1	10
Dual inhibition of KDM4B and KDM5A disassembles the PAX3-FOXO1 transcriptional program in fusion-positive rhabdomyosarcoma	9
ZNF750 suppresses esophageal squamous cell carcinoma by maintaining epithelial barrier–driven mucosal immune homeostasis	9
Impeding hypoxia-driven tumor progression in hepatocellular carcinoma: clinical and pre-clinical analyses using 2D and 3D in vitro models	9
Identification of M2 macrophage-related genes associated with diffuse large B-cell lymphoma via bioinformatics and machine learning approaches	9
Correction: Integrated Mendelian randomization and single-cell RNA-sequencing analyses identified OAS1 as a novel therapeutic target for erectile dysfunction via targeting fibroblasts	9
JUNB transcriptional regulation of KRT20 via ITGB1 activates PI3K/AKT signaling pathway against fibrosis-induced by renal injury	9
A functional approach to homeostatic regulation	9
Naringin and hesperidin protect ovarian granulosa cells from cisplatin-induced mitochondrial dysfunction by enhancing bioenergetics and mitophagy	9
Integrating machine learning models with multi-omics analysis to decipher the prognostic significance of mitotic catastrophe heterogeneity in bladder cancer	9
Single-cell analysis highlights the role of CD4+ IFN-I-related T cells in Behcet’s uveitis during Interferonα-2a therapy	9
In silico optimization of RNA–protein interactions for CRISPR-Cas13-based antimicrobials	9
Upregulation of long intergenic non-coding RNA LINC00326 inhibits non-small cell lung carcinoma progression by blocking Wnt/β-catenin pathway through modulating the miR-657/dickkopf WNT signaling path	9
Evolution of cell therapies derived from adipose tissue: historical perspectives, current development trends and future directions	9
miR-155 mediated regulation of PKG1 and its implications on cell invasion, migration, and apoptosis in preeclampsia through NF-κB pathway	9
Decoding the Snail transcriptional network: its role in cancer progression and therapy	9
m6A methylation-mediated lncRNA RNF144A-AS1 promotes hepatocellular carcinoma progression through the miR-1301-3p/RNF38 pathway	9
Correction: IPSC derived cardiac fibroblasts of DMD patients show compromised actin microfilaments, metabolic shift and pro-fibrotic phenotype	9
Robust SH2 binding affinity indicates minimal SH3-to-SH2 communication in Grb2	9
Circular RNA hsa_circ_0067842 facilitates tumor metastasis and immune escape in breast cancer through HuR/CMTM6/PD-L1 axis	8
Quinolinic acid impairs mitophagy promoting microglia senescence and poor healthspan in C. elegans: a mechanism of impaired aging process	8
Spleen granulopoiesis in psoriasis immune microenvironment aggravates psoriasis via IL-6/P-STAT3 signaling	8
Loss of AMPK activity induces organelle dysfunction and oxidative stress during oocyte aging	8
SETD7-mediated epigenetic regulation of LncRNA XIST promotes trophoblast pyroptosis: a study in preeclampsia mouse and cell models	8
LncRNA5251 inhibits spermatogenesis via modification of cell-cell junctions	8
KIF4A in disease pathogenesis and therapeutics: from molecular mechanisms to clinical translation	8
cGAS-STING targeting offers therapy choice in lung diseases	8
Host-mediated RNA editing in viruses	8
Myricetin attenuates experimental autoimmune prostatitis and inflammatory and oxidative injury in LPS-induced RWPE-1 cells potentially through modulation of MAPK/STAT3/NF-κB/Nrf2 signaling pathway	8
Fraxinellone-mediated targeting of cathepsin B leakage from lysosomes induces ferroptosis in fibroblasts to inhibit hypertrophic scar formation	8
USP19 alleviates LPS-induced acute lung injury via inhibiting TAK1 activation	8
ADSC-derived exosomes attenuate myocardial infarction injury by promoting miR-205-mediated cardiac angiogenesis	8

Comprehensive pan-cancer analysis indicates UCHL5 as a novel cancer biomarker and promotes cervical cancer progression through the Wnt signaling pathway	8
Construction of a prognostic model based on disulfidptosis-related genes and identification of CCNA2 as a novel biomarker for hepatocellular carcinoma	8
Integrative single-cell and bulk analyses reveal ATF4-associated immune suppression and WNT/β-catenin signaling in osteosarcoma	8
Unraveling the oxidative stress landscape in diabetic foot ulcers: insights from bulk RNA and single-cell RNA sequencing data	8
Circadian rhythms and microbiota: molecular crosstalk and its implications for health and disease	8
MYC promotes myocardial fibrosis via METTL1-mediated m7G modification of HILPDA	7
Prognostic model integrating histology, systemic inflammation, and recurrence status predicts immunotherapy response in advanced non-small-cell lung cancer patients	7
SIRT5-dependent desuccinylation licenses UBR5-mediated degradation of TAMM41 to regulate mitochondrial metabolism in lung adenocarcinoma	7
Did the early full genome sequencing of yeast boost gene function discovery?	7
A phospho-switch to trigger mitotic chromosome condensation	7
Ecological determinants of altruism in prokaryote antivirus defense	7
MiR-142-3p promotes radioresistance by targeting FOXO4 in colorectal cancer	7
Single-cell RNA sequencing reveals a new mechanism of endothelial cell heterogeneity and healing in diabetic foot ulcers	7
Affibodies as valuable tool to prevent β2m aggregation under lysosomal-like conditions	7
Ultrastructural studies distinguish skin diversities among Galápagos iguanas	7
Spinal apolipoprotein E is involved in inflammatory pain via regulating lipid metabolism and glial activation in the spinal dorsal horn	7
Identification of fatty acid metabolism-related lncRNAs in the prognosis and immune microenvironment of colon adenocarcinoma	7
Single-cell transcriptomics reveals cellular heterogeneity and macrophage-to-mesenchymal transition in bicuspid calcific aortic valve disease	7
Genomic characteristics and evolution of Multicentric Esophageal and gastric Cardiac Cancer	7
Unveiling the molecular profile of a prostate carcinoma: implications for personalized medicine	7
The CXCR3/PLC/IP3-IP3R axis is responsible for the ignition of UPR in intestinal epithelial cells exposed to gliadin peptide, during the onset of celiac disease	7
LncRNA Airn alleviates diabetic cardiac fibrosis by inhibiting activation of cardiac fibroblasts via a m6A-IMP2-p53 axis	6
Integrating Circle-Seq with transcriptomics reveals genome-wide characterization of extrachromosomal circular DNA for dilated cardiomyopathy	6
Proteomics and digital subtraction angiography approaches reveal CDH18 as a potential target for therapy of moyamoya disease	6
PNSC928, a plant-derived compound, specifically disrupts CtBP2-p300 interaction and reduces inflammation in mice with acute respiratory distress syndrome	6
AQP5 trafficking is regulated by its C-terminal tail and interaction with prolactin-inducible protein	6
The miR-143/145 cluster in prostate cancer: molecular regulation, context-dependent functions, and medical implications	6
scE2EGAE: enhancing single-cell RNA-Seq data analysis through an end-to-end cell-graph-learnable graph autoencoder with differentiable edge sampling	6
m6A-mediated upregulation of LINC01003 regulates cell migration by targeting the CAV1/FAK signaling pathway in glioma	6
Novel genetic insights into causal effects of potential metformin targets and immune mediation on sepsis	6
Deep learning-assisted high-content screening identifies isoliquiritigenin as an inhibitor of DNA double-strand breaks for preventing doxorubicin-induced cardiotoxicity	6
PLIN3 overexpression in lung adenocarcinoma promotes M2 macrophage–myofibroblast transition in the tumor microenvironment	6
Obesity-associated lysosomal nitrosative stress promotes retinopathy	6
Elevated NDUFAF2 expression correlates with poor prognosis and drives metabolic dependency in hepatocellular carcinoma	6
Autophagy is influenced by vitamin D3 level in people with HIV-1	6
Long-read assembly of major histocompatibility complex and killer cell immunoglobulin-like receptor genome regions in cynomolgus macaque	6
Identification and functional validation of mitochondria-related genes associated with tubular injury in kidney transplantation and ischemia–reperfusion injury	6
METTL3 in cancer-associated fibroblasts-derived exosomes promotes the proliferation and metastasis and suppresses ferroptosis in colorectal cancer by eliciting ACSL3 m6A modification	6
METTL3-induced lncRNA GBAP1 promotes hepatocellular carcinoma progression by activating BMP/SMAD pathway	6
Elevated SREBP1 accelerates the initiation and growth of pancreatic cancer by targeting SOX9	6
Mammalian enabled protein enhances tamoxifen sensitivity of the hormone receptor-positive breast cancer patients by suppressing the AKT signaling pathway	6
Identifying the driver miRNAs with somatic copy number alterations driving dysregulated ceRNA networks in cancers	6
Antitumoral effects of Bortezomib in malignant mesothelioma: evidence of mild endoplasmic reticulum stress in vitro and activation of T cell response in vivo	6
In-silico study of machine learning discovers de novo lipogenesis for predicting prognosis and immunotherapy responses in kidney renal clear cell carcinoma	5
Integrated machine learning reveals the role of tryptophan metabolism in clear cell renal cell carcinoma and its association with patient prognosis	5
PLAU promotes growth and attenuates cisplatin chemosensitivity in ARID1A-depleted non-small cell lung cancer through interaction with TM4SF1	5
Dynamic expression of IGFBP3 modulate dual actions of mineralization micro-environment during tooth development via Wnt/beta-catenin signaling pathway	5
Exploring the association between osteoporosis and kidney stones: a clinical to mechanistic translational study based on big data and bioinformatics	5
Depletion of LONP2 unmasks differential requirements for peroxisomal function between cell types and in cholesterol metabolism	5
Phosphodiesterase type 5 inhibitor tadalafil reduces prostatic fibrosis via MiR-3126-3p/FGF9 axis in benign prostatic hyperplasia	5
Integrating multi-layered biological priors to improve genomic prediction accuracy in beef cattle	5
Vemurafenib induces senescence in acute myeloid leukemia and myelodysplastic syndrome by activating the HIPPO signaling pathway: implications for potential targeted therapy	5
Horizontal transfer of matrix metalloproteinase genes links early animal and microbial evolution	5
MIR194-2HG, a miRNA host gene activated by HNF4A, inhibits gastric cancer by regulating microRNA biogenesis	5
CircRNA_15430 reduced by Helicobacter pylori infection and suppressed gastric cancer progression via miR-382-5p/ZCCHC14 axis	5
Functional genomic imaging (FGI), a virtual tool for visualization of functional gene expression modules in heterogeneous tumor samples	5
ACSM5 inhibits ligamentum flavum hypertrophy by regulating lipid accumulation mediated by FABP4/PPAR signaling pathway	5
Valentina Tassinari, the legacy of a young scientist	5
NCOA4-mediated ferritinophagy modulates colitis-associated ferroptosis in intestinal epithelial cells and mucosal repair	5
Efficient DNA-free co-targeting of nuclear genes in Chlamydomonas reinhardtii	5
Sigma-1 receptor activation attenuates DOX-induced cardiotoxicity by alleviating endoplasmic reticulum stress and mitochondrial calcium overload via PERK and IP3R-VDAC1-MCU signaling pathways	5
GPR137 inactivates Hippo signaling to promote gastric cancer cell malignancy	5
Integrative bioinformatics approach to the mRNA vaccine development for the human papillomavirus using the capsid protein	5
Lysine-specific methyltransferase Set7/9 in stemness, differentiation, and development	5
Hypoxia-induced activation of HIF-1alpha/IL-1beta axis in microglia promotes glioma progression via NF-κB-mediated upregulation of heparanase expression	5
Deubiquitination of DNM1L by USP3 triggers the development and metastasis of gallbladder carcinoma	5
An integrated microbiome-drug interaction and bioinformatics approach identifies active deglycosylated and glycosidic chain metabolites of Platycodin D targeting PTPN2/HIF1A in acute lung injury	5
Identification of novel snoRNA-based biomarkers for clear cell renal cell carcinoma from urine-derived extracellular vesicles	5
Analysis of lineage-specific protein family variability in prokaryotes combined with evolutionary reconstructions	5
A glutamine metabolish-associated prognostic model to predict prognosis and therapeutic responses of hepatocellular carcinoma	5
Exploring and experimental validation of SLC7A11 and ferroptosis related prognostic genes in non-small cell lung cancer using bulk RNA sequencing and single-cell RNA sequencing	5
TIMM8B promotes oxidative phosphorylation and glycolysis by inhibiting the mtROS/ASK1/JNK signaling pathway in ovarian cancer	5
m5C RNA modification in gastrointestinal cancers: a comprehensive review from molecular mechanism to clinical implication	5
A cyclin D1–CDK4/6–E2F dependency represents an acquired vulnerability in cisplatin-resistant bladder cancer	5
Early-stage administration of hydroxytyrosol extends lifespan and delays aging in C. elegans	4
Correction: ILC1-derived IFN-γ regulates macrophage activation in colon cancer	4
Active enhancers: recent research advances and insights into disease	4
GALNT9 enrichment attenuates MPP+-induced cytotoxicity by ameliorating protein aggregations containing α-synuclein and mitochondrial dysfunction	4
A novel TAp63γ–Airn regulatory axis governs early myogenic gene networks	4
Coordinating energy metabolism and signaling pathways in epithelial self-renewal and differentiation	4
E3 ligase HERC5-catalyzed UGDH isgylation promotes SNAI1-mediated tumor metastasis and cisplatin resistance in oral squamous cell carcinoma	4
FAM83D facilitates EMT and metastasis of cervical cancer via interaction with GSK3β and inactivation of GSK3β/stabilization of Snail signaling	4
Total network controllability analysis discovers explainable drugs for Covid-19 treatment	4
Transcriptional diversity in specific synaptic gene sets discriminates cortical neuronal identity	4
Breaking barriers: improving time and space resolution of arbuscular mycorrhizal symbiosis with single-cell sequencing approaches	4
NSDHL as a regulator of lipid peroxidation and ER stress–mediated apoptosis in ovarian cancer	4
BRD4 sustains p63 transcriptional program in keratinocytes	4
Isolation and characterization of novel bacteriophages with broad-spectrum lytic activity against carbapenem-resistant Klebsiella pneumoniae capsular pathotypes K1, K2, K3, K5, and K20	4
Multi-omics analysis of deep brain stimulation associated with brain-gut axis modulation and symptom amelioration in a Parkinson’s disease mouse model	4
OTUD5 promotes the growth of hepatocellular carcinoma by deubiquitinating and stabilizing SLC38A1	4
Combined treatment of nerve growth factor and transcranical direct current stimulations to improve outcome in children with vegetative state after out-of-hospital cardiac arrest	4
Disulfidptosis signature predicts immune microenvironment and prognosis of gastric cancer	4
miR-210 is essential to retinal homeostasis in fruit flies and mice	4
RETRACTED ARTICLE: Regulating ferroptosis by non-coding RNAs in hepatocellular carcinoma	4
Overexpression of ZNF488 supports pancreatic cancer cell proliferation and tumorigenesis through inhibition of ferroptosis via regulating SCD1-mediated unsaturated fatty acid metabolism	4