OOIR: Observatory of International Research

Papers

(The TQCC of Molecular Pain is 5. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-04-01 to 2024-04-01.)

Article	Citations
Short-chain fatty acids contribute to neuropathic pain via regulating microglia activation and polarization	34
Electroacupuncture may alleviate neuropathic pain via suppressing P2X7R expression	30
Modulation of microglial activation states by spinal cord stimulation in an animal model of neuropathic pain: Comparing high rate, low rate, and differential target multiplexed programming	23
A systematic review on descending serotonergic projections and modulation of spinal nociception in chronic neuropathic pain and after spinal cord stimulation	22
Neurokinins and their receptors in the rat trigeminal system: Differential localization and release with implications for migraine pain	16
Genome-wide association study identifies candidate loci associated with chronic pain and postherpetic neuralgia	15
Trigeminal neuralgia and genetics: A systematic review	14
Epigenetic modifications in neuropathic pain	14
SUR1, newly expressed in astrocytes, mediates neuropathic pain in a mouse model of peripheral nerve injury	12
Spinally projecting noradrenergic neurons of the locus coeruleus display resistance to AAV2retro-mediated transduction	11
Pra-C exerts analgesic effect through inhibiting microglial activation in anterior cingulate cortex in complete Freund’s adjuvant-induced mouse model	11
MicroRNA-137-mediated inhibition of lysine-specific demethylase-1 prevents against rheumatoid arthritis in an association with the REST/mTOR axis	11
Characterisation of deep dorsal horn projection neurons in the spinal cord of the Phox2a::Cre mouse line	10
Inhibition of calcium-stimulated adenylyl cyclase subtype 1 (AC1) for the treatment of neuropathic and inflammatory pain in adult female mice	10
Inflammation in pathogenesis of chronic pain: Foe and friend	10
Agmatine requires GluN2B-containing NMDA receptors to inhibit the development of neuropathic pain	10
Transcriptome analysis reveals dysregulation of inflammatory and neuronal function in dorsal root ganglion of paclitaxel-induced peripheral neuropathy rats	9
Differential target multiplexed spinal cord stimulation programming modulates proteins involved in ion regulation in an animal model of neuropathic pain	9
Berberine elevates mitochondrial membrane potential and decreases reactive oxygen species by inhibiting the Rho/ROCK pathway in rats with diabetic encephalopathy	9
The interaction between P2X3 and TRPV1 in the dorsal root ganglia of adult rats with different pathological pains	9
Tetrahydropalmatine exerts analgesic effects by promoting apoptosis and inhibiting the activation of glial cells in rats with inflammatory pain	9
Cortical mechanisms in migraine	9
P2X7 receptor induces microglia polarization to the M1 phenotype in cancer-induced bone pain rat models	8
Mapping thalamic-anterior cingulate monosynaptic inputs in adult mice	8
Cold pain sensitivity is associated with single-nucleotide polymorphisms of PAR2/F2RL1 and TRPM8	8

NMDA Receptor-Dependent Synaptic Depression in Potentiated Synapses of the Anterior Cingulate Cortex of adult Mice	8
Distinct roles of GT1b and CSF-1 in microglia activation in nerve injury-induced neuropathic pain	8
Dimethyl fumarate attenuates pain behaviors in osteoarthritis rats via induction of Nrf2-mediated mitochondrial biogenesis	8
Tricyclic antidepressants and selective serotonin reuptake inhibitors but not anticonvulsants ameliorate pain, anxiety, and depression symptoms in an animal model of central post-stroke pain	8
Cellular and synaptic mechanisms for Parkinson’s disease-related chronic pain	8
Inhibiting spinal secretory phospholipase A₂ after painful nerve root injury attenuates established pain and spinal neuronal hyperexcitability by altering spinal glutamatergic signaling	8
Systemic administration of a β2-adrenergic receptor agonist reduces mechanical allodynia and suppresses the immune response to surgery in a rat model of persistent post-incisional hypersensitivity	7
Whole-brain mapping of efferent projections of the anterior cingulate cortex in adult male mice	7
Spinal NLRP3 inflammasome activation mediates IL-1β release and contributes to remifentanil-induced postoperative hyperalgesia by regulating NMDA receptor NR1 subunit phosphorylation and GLT-1 express	7
Spinal 5-HT_2A receptor is involved in electroacupuncture inhibition of chronic pain	7
Ion channels and pain in Fabry disease	7
Trigeminal neuropathic pain causes changes in affective processing of pain in rats	6
Dysfunctional energy metabolisms in fibromyalgia compared with healthy subjects	6
Epigenetic age predictors in community-dwelling adults with high impact knee pain	6
Analgesic effect of gastrin-releasing peptide in the dorsal horn	6
Review of complex regional pain syndrome and the role of the neuroimmune axis	6
Persistent inflammatory pain is linked with anxiety-like behaviors, increased blood corticosterone, and reduced global DNA methylation in the rat amygdala	6
Blockade of BK channels attenuates chronic visceral hypersensitivity in an IBS-like rat model	6
KCC2 receptor upregulation potentiates antinociceptive effect of GABAAR agonist on remifentanil-induced hyperalgesia	6
Selective inhibition of adenylyl cyclase subtype 1 reduces inflammatory pain in chicken of gouty arthritis	6
Enhanced function of NR2C/2D-containing NMDA receptor in the nucleus accumbens contributes to peripheral nerve injury-induced neuropathic pain and depression in mice	6
Inhibition of the phosphoinositide 3-kinase-AKT-cyclic GMP-c-Jun N-terminal kinase signaling pathway attenuates the development of morphine tolerance in a mouse model of neuropathic pain	6
Neuropeptide W, an endogenous NPBW1 and NPBW2 ligand, produced an analgesic effect via activation of the descending pain modulatory system during a rat formalin test	6
Ginsenoside Rh2 Ameliorates Neuropathic Pain by inhibition of the miRNA21-TLR8-mitogen-activated protein kinase axis	5
Human safety study of a selective neuronal adenylate cyclase 1 inhibitor NB001 which relieves the neuropathic pain and blocks ACC in adult mice	5
Brain Structure and Function of Chronic Low Back Pain Patients on Long-Term Opioid Analgesic Treatment: A Preliminary Study	5
The brinker repressor system regulates injury-induced nociceptive sensitization in Drosophila melanogaster	5
Spinal GABAergic neurons are under feed-forward inhibitory control driven by Aδ and C fibers in Gad2 td-Tomato mice	5
The analgesic effects of β-elemene in rats with neuropathic pain by inhibition of spinal astrocytic ERK activation	5
Analgesic characteristics of a newly developed α₂δ ligand, mirogabalin, on inflammatory pain	5
Single-nucleotide polymorphisms of the SLC17A9 and P2RY12 genes are significantly associated with phantom tooth pain	5
Roles of mast cells and their interactions with the trigeminal nerve in migraine headache	5
Emodin alleviates arthritis pain through reducing spinal inflammation and oxidative stress	5
CXCR1 participates in bone cancer pain induced by Walker 256 breast cancer cells in female rats	5
Targeting Vascular endothelial growth factor A with soluble vascular endothelial growth factor receptor 1 ameliorates nerve injury-induced neuropathic pain	5