OOIR: Observatory of International Research

Papers

(The TQCC of Molecular Pain is 5. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-02-01 to 2025-02-01.)

Article	Citations
Projections from infralimbic medial prefrontal cortex glutamatergic outputs to amygdala mediates opioid induced hyperalgesia in male rats	33
Transcription factor ETS proto-oncogene 1 contributes to neuropathic pain by regulating histone deacetylase 1 in primary afferent neurons	21
Electroacupuncture attenuates nociceptive behaviors in a mouse model of cancer pain	18
Morphine acts in vitro to directly prime nociceptors	16
Role of ERK in gender difference of fibromyalgia pain	15
Corrigendum to “Rac1/PAK1 signaling contributes to bone cancer pain by Regulation dendritic spine remodeling in rats”	14
Acute pulpitis promotes purinergic signaling to induce pain in rats via P38MAPK/NF-κB signaling pathway	12
Silencing of TRPV4-expressing sensory neurons attenuates temporomandibular disorders pain	12
Contribution of immune cells to cancer-related neuropathic pain: An updated review	12
Modulation of melatonin to the thalamic lesion-induced pain and comorbid sleep disturbance in the animal model of the central post-stroke hemorrhage	12
Sound-induced analgesia cannot always be observed in adult mice	11
Whole-brain mapping of efferent projections of the anterior cingulate cortex in adult male mice	11
Neural Adaptation of the Reward System in Primary Dysmenorrhea	11
Isolectin B4 (IB4)-conjugated streptavidin for the selective knockdown of proteins in IB4-positive (+) nociceptors	10
Sophoridine alleviates hyperalgesia and anxiety-like behavior in an inflammatory pain mouse model induced by complete freund’s adjuvant	10
Compartmentalized primary cultures of dorsal root ganglion neurons to model peripheral pathophysiological conditions	10
microRNA-181a contributes to gastric hypersensitivity in rats with diabetes by regulating TLR4 expression	9
Predicting long-term pain by combining brain imaging, genetics and health questionnaire data with Swedish national registries using a prospective superstruct design	9
T-type Ca²⁺ channels play a dual role in modulating the excitability of dorsal root ganglia neurons	9
KCC2 receptor upregulation potentiates antinociceptive effect of GABAAR agonist on remifentanil-induced hyperalgesia	9
Mechanisms of acupuncture–electroacupuncture on inflammatory pain	9
Characterisation of deep dorsal horn projection neurons in the spinal cord of the Phox2a::Cre mouse line	8
Cholinergic modulation is independent of T lymphocytes in a mouse model of neuropathic pain	8
Esketamine inhibits the c-Jun N-terminal kinase pathway in the spinal dorsal horn to relieve bone cancer pain in rats	8
Electroacupuncture improves allodynia and central sensitization via modulation of microglial activation associated P2X4R and inflammation in a rat model of migraine	8

Epigenetic age predictors in community-dwelling adults with high impact knee pain	8
Analgesic effect of gastrin-releasing peptide in the dorsal horn	8
Emodin alleviates arthritis pain through reducing spinal inflammation and oxidative stress	7
Mapping thalamic-anterior cingulate monosynaptic inputs in adult mice	7
Duloxetine prevents bortezomib and paclitaxel large-fiber chemotherapy-induced peripheral neuropathy (LF-CIPN) in sprague dawley rats	7
The analgesic effects of β-elemene in rats with neuropathic pain by inhibition of spinal astrocytic ERK activation	7
Effects of pain in lumbosacral stenosis and lifestyle-related factors on brain-derived neurotrophic factor expression profiles	7
A-kinase anchoring protein 79/150 coordinates α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor sensitization in sensory neurons	7
Dehydrocorydaline alleviates sleep deprivation-induced persistent postoperative pain in adolescent mice through inhibiting microglial P2Y₁₂ receptor expression in the spinal cord	7
Human safety study of a selective neuronal adenylate cyclase 1 inhibitor NB001 which relieves the neuropathic pain and blocks ACC in adult mice	6
Whole-brain mapping of afferents to the anterior cingulate cortex in adult mice	6
Armadillo regulates nociceptive sensitivity in the absence of injury	6
Activation of neurons and satellite glial cells in the DRG produces morphine-induced hyperalgesia	6
Effects of administration of α₂ adrenergic receptor agonist into psoas major muscle on inflammatory pain induced by injection of complete Freund’s adjuvant in rats	6
Urolithin A alleviates neuropathic pain and activates mitophagy	6
RETRACTED: Activation of the P2X7 receptor in the dental pulp tissue contributes to the pain in rats with acute pulpitis	6
Pain sensitivity genes as therapeutic targets in knee osteoarthritis: A comprehensive analysis	6
Dimethyl fumarate attenuates pain behaviors in osteoarthritis rats via induction of Nrf2-mediated mitochondrial biogenesis	5
Histamine H4 receptor and TRPV1 mediate itch induced by cadaverine, a metabolite of the microbiome	5
Causal associations of immune cell phenotypes with migraine: A mendelian randomization study	5
Peripheral sensory neurons and non-neuronal cells express functional Piezo1 channels	5
The increased iron deposition of the gray matter over the whole brain in chronic migraine: An exploratory quantitative susceptibility mapping study	5
Concomitant use of pre-emptive analgesia with local and general anesthesia in rat uterine pain surgical model	5
Assessment of orofacial nociceptive behaviors of mice with the sheltering tube method: Oxaliplatin-induced mechanical and cold allodynia in orofacial regions	5
Kilohertz high-frequency electrical stimulation ameliorate hyperalgesia by modulating transient receptor potential vanilloid-1 and N-methyl-D-aspartate receptor-2B signaling pathways in chronic constr	5
Xanthohumol relieves arthritis pain in mice by suppressing mitochondrial-mediated inflammation	5
Methyltransferase-like 3 modulates visceral hypersensitivity through regulating the nuclear export of circKcnk9 in YTHDC1-dependent manner	5