OOIR: Observatory of International Research

Papers

(The median citation count of Molecular Pain is 2. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-02-01 to 2025-02-01.)

Article	Citations
Projections from infralimbic medial prefrontal cortex glutamatergic outputs to amygdala mediates opioid induced hyperalgesia in male rats	33
Transcription factor ETS proto-oncogene 1 contributes to neuropathic pain by regulating histone deacetylase 1 in primary afferent neurons	21
Electroacupuncture attenuates nociceptive behaviors in a mouse model of cancer pain	18
Morphine acts in vitro to directly prime nociceptors	16
Role of ERK in gender difference of fibromyalgia pain	15
Corrigendum to “Rac1/PAK1 signaling contributes to bone cancer pain by Regulation dendritic spine remodeling in rats”	14
Contribution of immune cells to cancer-related neuropathic pain: An updated review	12
Modulation of melatonin to the thalamic lesion-induced pain and comorbid sleep disturbance in the animal model of the central post-stroke hemorrhage	12
Acute pulpitis promotes purinergic signaling to induce pain in rats via P38MAPK/NF-κB signaling pathway	12
Silencing of TRPV4-expressing sensory neurons attenuates temporomandibular disorders pain	12
Whole-brain mapping of efferent projections of the anterior cingulate cortex in adult male mice	11
Neural Adaptation of the Reward System in Primary Dysmenorrhea	11
Sound-induced analgesia cannot always be observed in adult mice	11
Sophoridine alleviates hyperalgesia and anxiety-like behavior in an inflammatory pain mouse model induced by complete freund’s adjuvant	10
Compartmentalized primary cultures of dorsal root ganglion neurons to model peripheral pathophysiological conditions	10
Isolectin B4 (IB4)-conjugated streptavidin for the selective knockdown of proteins in IB4-positive (+) nociceptors	10
T-type Ca²⁺ channels play a dual role in modulating the excitability of dorsal root ganglia neurons	9
KCC2 receptor upregulation potentiates antinociceptive effect of GABAAR agonist on remifentanil-induced hyperalgesia	9
Mechanisms of acupuncture–electroacupuncture on inflammatory pain	9
microRNA-181a contributes to gastric hypersensitivity in rats with diabetes by regulating TLR4 expression	9
Predicting long-term pain by combining brain imaging, genetics and health questionnaire data with Swedish national registries using a prospective superstruct design	9
Esketamine inhibits the c-Jun N-terminal kinase pathway in the spinal dorsal horn to relieve bone cancer pain in rats	8
Electroacupuncture improves allodynia and central sensitization via modulation of microglial activation associated P2X4R and inflammation in a rat model of migraine	8
Epigenetic age predictors in community-dwelling adults with high impact knee pain	8
Analgesic effect of gastrin-releasing peptide in the dorsal horn	8

Characterisation of deep dorsal horn projection neurons in the spinal cord of the Phox2a::Cre mouse line	8
Cholinergic modulation is independent of T lymphocytes in a mouse model of neuropathic pain	8
The analgesic effects of β-elemene in rats with neuropathic pain by inhibition of spinal astrocytic ERK activation	7
Effects of pain in lumbosacral stenosis and lifestyle-related factors on brain-derived neurotrophic factor expression profiles	7
A-kinase anchoring protein 79/150 coordinates α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor sensitization in sensory neurons	7
Dehydrocorydaline alleviates sleep deprivation-induced persistent postoperative pain in adolescent mice through inhibiting microglial P2Y₁₂ receptor expression in the spinal cord	7
Emodin alleviates arthritis pain through reducing spinal inflammation and oxidative stress	7
Mapping thalamic-anterior cingulate monosynaptic inputs in adult mice	7
Duloxetine prevents bortezomib and paclitaxel large-fiber chemotherapy-induced peripheral neuropathy (LF-CIPN) in sprague dawley rats	7
Urolithin A alleviates neuropathic pain and activates mitophagy	6
RETRACTED: Activation of the P2X7 receptor in the dental pulp tissue contributes to the pain in rats with acute pulpitis	6
Pain sensitivity genes as therapeutic targets in knee osteoarthritis: A comprehensive analysis	6
Human safety study of a selective neuronal adenylate cyclase 1 inhibitor NB001 which relieves the neuropathic pain and blocks ACC in adult mice	6
Whole-brain mapping of afferents to the anterior cingulate cortex in adult mice	6
Armadillo regulates nociceptive sensitivity in the absence of injury	6
Activation of neurons and satellite glial cells in the DRG produces morphine-induced hyperalgesia	6
Effects of administration of α₂ adrenergic receptor agonist into psoas major muscle on inflammatory pain induced by injection of complete Freund’s adjuvant in rats	6
Peripheral sensory neurons and non-neuronal cells express functional Piezo1 channels	5
The increased iron deposition of the gray matter over the whole brain in chronic migraine: An exploratory quantitative susceptibility mapping study	5
Concomitant use of pre-emptive analgesia with local and general anesthesia in rat uterine pain surgical model	5
Assessment of orofacial nociceptive behaviors of mice with the sheltering tube method: Oxaliplatin-induced mechanical and cold allodynia in orofacial regions	5
Kilohertz high-frequency electrical stimulation ameliorate hyperalgesia by modulating transient receptor potential vanilloid-1 and N-methyl-D-aspartate receptor-2B signaling pathways in chronic constr	5
Xanthohumol relieves arthritis pain in mice by suppressing mitochondrial-mediated inflammation	5
Methyltransferase-like 3 modulates visceral hypersensitivity through regulating the nuclear export of circKcnk9 in YTHDC1-dependent manner	5
Dimethyl fumarate attenuates pain behaviors in osteoarthritis rats via induction of Nrf2-mediated mitochondrial biogenesis	5
Histamine H4 receptor and TRPV1 mediate itch induced by cadaverine, a metabolite of the microbiome	5
Causal associations of immune cell phenotypes with migraine: A mendelian randomization study	5
A novel anti-pruritic: Topical co-administration of high molecular weight hyaluronan (HMWH) with protamine, a transdermal transport enhancer	4
L-Acetylcarnitine causes analgesia in mice modeling Fabry disease by up-regulating type-2 metabotropic glutamate receptors	4
Reduced capsaicin-induced mechanical allodynia and neuronal responses in the dorsal root ganglion in the presence of protein tyrosine phosphatase non-receptor type 6 overexpression	4
Effects of systemic oxytocin administration on ultraviolet B-induced nociceptive hypersensitivity and tactile hyposensitivity in mice	4
Offset analgesia is associated with opposing modulation of medial versus dorsolateral prefrontal cortex activations: A functional near-infrared spectroscopy study	4
Roles of mast cells and their interactions with the trigeminal nerve in migraine headache	4
Altered intra- and inter-network functional activity among migraine, chronic migraine, and trigeminal neuralgia	4
Involvement of interferon gamma signaling in spinal trigeminal caudal subnucleus astrocyte in orofacial neuropathic pain in rats with infraorbital nerve injury	4
Dorsal column and root stimulation at Aβ-fiber intensity activate superficial dorsal horn glutamatergic and GABAergic populations	4
Phenotypic screen identifies the natural product silymarin as a novel anti-inflammatory analgesic	4
Assessment of pain-related behaviors in HIV-1 transgenic rats as a model of HIV-associated chronic pain	4
Evaluation of the concentration of growth associated protein-43 and glial cell-derived neurotrophic factor in degenerated intervertebral discs of the lumbosacral region of the spine	4
Protectin D1 ameliorates non-compressive lumbar disc herniation through SIRT1-mediated CGRP signaling	4
Newly discovered functions of miRNAs in neuropathic pain: Transitioning from recent discoveries to innovative underlying mechanisms	4
Polysorbate 80 blocked a peripheral sodium channel, Na_v1.7, and reduced neuronal excitability	4
The effects of chronic high-dose morphine on microgliosis and the microglial transcriptome in rat spinal cord	3
Vascular endothelial growth factor-A/vascular endothelial growth factor2 signaling in spinal neurons contributes to bone cancer pain	3
Ginsenoside Rh2 Ameliorates Neuropathic Pain by inhibition of the miRNA21-TLR8-mitogen-activated protein kinase axis	3
Fat mass and obesity-related protein contributes to the development and maintenance of bone cancer pain in rats by abrogating m6A methylation of RNA	3
Genetic evidence of the function of Phox2a-expressing anterolateral system neurons in the transmission of chronic pain	3
Co-Administration of nalbuphine to improve morphine tolerance in mice with bone cancer pain	3
The transcription factor CCAAT/enhancer-binding protein β in spinal microglia contributes to pre-operative stress-induced prolongation of postsurgical pain	3
Recruitment of cortical silent responses by forskolin in the anterior cingulate cortex of adult mice	3

Sigma-1 receptors and progesterone metabolizing enzymes in nociceptive sensory neurons of the female rat trigeminal ganglia: A neural substrate for the antinociceptive actions of progesterone	3
Nociceptive signaling through transient receptor potential vanilloid 1 is regulated by Cyclin Dependent Kinase 5-mediated phosphorylation of T407 in vivo	3
Phytohormone abscisic acid ameliorates neuropathic pain via regulating LANCL2 protein abundance and glial activation at the spinal cord	3
Genetic basis of thermal nociceptive sensitivity and brain weight in a BALB/c reduced complexity cross	3
Oxytocin inhibits hindpaw hyperalgesia induced by orofacial inflammation combined with stress	3
Effects on low threshold mechanoreceptors in whisker hair follicles by 5-HT, Cd²⁺, tetraethylammonium, 4-aminopyridine, and Ba²⁺	3
Sub-anaesthetic dose of propofol attenuates mechanical allodynia in chronic post-ischaemic pain via regulation of PTEN/PI3K/IL-6 signalling	3
Neurotropin^® ameliorates chronic pain associated with scar formation in a mouse model: A gene expression analysis of the inflammatory response	3
Persistent inflammatory pain is linked with anxiety-like behaviors, increased blood corticosterone, and reduced global DNA methylation in the rat amygdala	2
Toll-like receptor 4 signaling pathway in sensory neurons mediates remifentanil-induced postoperative hyperalgesia via transient receptor potential ankyrin 1	2
Grape seed-derived procyanidins decreases neuropathic pain and nerve regeneration by suppression of toll-like receptor 4-myeloid differentiation factor-88 signaling	2
Resolvin D1 attenuates mechanical allodynia after burn injury: Involvement of spinal glia, p38 mitogen-activated protein kinase, and brain-derived neurotrophic factor/tropomyosin-related kinase B sign	2
Dopamine receptor D2, but not D1, mediates the reward circuit from the ventral tegmental area to the central amygdala, which is involved in pain relief	2
The analgesic effects of botulinum neurotoxin by modulating pain-related receptors; A literature review	2
A note on estimating absolute cytosolic Ca²⁺ concentration in sensory neurons using a single wavelength Ca²⁺ indicator	2
Increased ten-eleven translocation methylcytosine dioxygenase one in dorsal root ganglion contributes to inflammatory pain in CFA rats	2
Glutamate acts as a key neurotransmitter for itch in the mammalian spinal cord	2
ARG1 and CXCL2 are potential biomarkers target for psoriasis patients	2
Phytochemical quercetin alleviates hyperexcitability of trigeminal nociceptive neurons associated with inflammatory hyperalgesia comparable to NSAIDs	2
Pain and aging: A unique challenge in neuroinflammation and behavior	2
Upregulation of KDM6B in the anterior cingulate cortex contributes to neonatal maternal deprivation-induced chronic visceral pain in mice	2
Spinal microRNA-134-5p targets glutamate receptor ionotropic kainate 3 to modulate opioid induced hyperalgesia in mice	2
Acute sleep deprivation aggravates nitroglycerin-evoked hyperalgesia in mice	2
Methylglyoxal activates transient receptor potential A1/V1 via reactive oxygen species in the spinal dorsal horn	2