OOIR: Observatory of International Research

Papers

(The TQCC of Expert Review of Clinical Immunology is 7. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-05-01 to 2025-05-01.)

Article	Citations
Pioglitazone as a potential modulator in autoimmune diseases: a review on its effects in systemic lupus erythematosus, psoriasis, inflammatory bowel disease, and multiple sclerosis	112
Bradford Hill and breast implant illness: no evidence for causal association with breast implants	88
How could our genetics impact COVID-19 vaccine response?	83
A critical review of dupilumab for adult patients with prurigo nodularis	79
Aleukemic variant of T-cell large granular lymphocyte leukemia in patients with rheumatoid arthritis - diagnostically challenging subtype	64
Will SARS-CoV-2 impact the incidence and nature of other respiratory infections?	59
The multidisciplinary approach to diagnosing inborn errors of immunity: a comprehensive review of discipline-based manifestations	59
Immunobiology and treatment of cutaneous T-cell lymphoma	58
Bimekizumab for the treatment of psoriatic arthritis	51
Pan-cancer analysis of the prognostic significance of ACKR2 expression and the related genetic/epigenetic dysregulations	46
A prospective single-arm study on the efficacy and safety of short-course oral corticosteroids followed by topical corticosteroids in patients with severe chronic rhinosinusitis with nasal polyps	36
More than a random association between chronic obstructive pulmonary disease and psoriatic arthritis: shared pathogenic features and implications for treatment	32
The effect of intense pulsed light combined with topical 0.05% Cyclosporin A eyedrops in the treatment of Sjögren’s syndrome related dry eye	32
The therapeutic effect of mRNA vaccines in glioma: a comprehensive review	32
Differential risk of autoimmune disorders in non-traumatic osteonecrosis: clue to pathogenesis	31
IRF1 expression might be a biomarker of CD8+ T cell infiltration in cutaneous melanoma	31
Dupilumab in chronic rhinosinusitis with nasal polyposis: current status, challenges, and future perspectives	28
Biomarkers guiding biological therapeutic strategies in chronic rhinosinusitis with nasal polyps: an emerging challenge	28
How to and should we target EBV in MS?	27
Re-evaluation of nailfold capillaroscopy in discriminating primary from secondary Raynaud’s phenomenon and in predicting systemic sclerosis: a randomised observational prospective cohort study	27
Pathogen-specific cell-mediated immunity to guide the management of cytomegalovirus in solid organ transplantation: state of the art clinical review	26
Food immunotherapy: current status and future needs	25
Antiphospholipid antibodies and osteonecrosis in systemic lupus erythematosus: a meta-analysis	25
Ruxolitinib as the first post-steroid treatment for acute and chronic graft-versus-host disease	23
Evaluating the use of JAK inhibitors in inflammatory connective tissue diseases in pediatric patients: an update	22

Pharmacokinetics and tolerability of prefilled syringe and auto-injector presentations of MSB11456: results of a randomized, single-dose study in healthy adults	21
Gut immune homeostasis: the immunomodulatory role of Bacillus clausii, from basic to clinical evidence	20
Neurological adverse effects of chimeric antigen receptor T-cell therapy	20
Emergence of an adaptive immune paradigm to explain celiac disease: a perspective on new evidence and implications for future interventions and diagnosis	20
How do nuclear factor kappa B (NF-κB)1 and NF-κB2 defects lead to the incidence of clinical and immunological manifestations of inborn errors of immunity?	20
Direct economic burden 1 year postoperation in Chinese adult patients with chronic rhinosinusitis with nasal polyps	20
Rare forms of inflammatory myopathies – part I, generalized forms	18
Advances in therapeutic targeting of immune checkpoints receptors within the CD96-TIGIT axis: clinical implications and future perspectives	18
Durability and long-term outcomes of biologic therapies in psoriasis	18
Recent insights into the pathogenesis of autoimmune hypophysitis	17
An exercise immune fitness test to unravel mechanisms of Post-Acute Sequelae of COVID-19	17
Current treatment options and long-term outcomes in patients with eosinophilic esophagitis	16
Impact of anti-PD1 immunotherapy and circulating tumor cells on progression-free survival in surgical pancreatic adenocarcinoma: a retrospective cohort study	16
Transcriptional regulation of B cell class-switch recombination: the role in development of noninfectious complications	16
Pathophysiology and management of Staphylococcus aureus in nasal polyp disease	15
Inflammatory myopathy in adults, health-related quality of life, and wellbeing: a round trip between immune disease and wellness	15
T-lymphocyte depleted transplants for inborn errors of immunity	15
Classification and management strategies for paediatric chronic nonbacterial osteomyelitis and chronic recurrent multifocal osteomyelitis	15
The functional role and the clinical application of periostin in chronic rhinosinusitis	15
Advancements in immunotherapy for advanced esophageal squamous cell carcinoma: a comprehensive review of current strategies and future directions	14
Recent insights into comorbidities in atopic dermatitis	14
An updated evaluation of avatrombopag for the treatment of chronic immune thrombocytopenia	14
Sicca syndrome/Sjögren’s disease associated with cancer immunotherapy: a narrative review on clinical presentation, biomarkers, and management	14
Immune mechanisms, the role of complement, and related therapies in autoimmune neuropathies	13
Challenges in uncontrolled asthma in pediatrics: important considerations for the clinician	13
Perspectives for immunotherapy in noninfectious immune mediated uveitis	13
Transcriptomic observations of intra and extracellular immunotherapy targets for pediatric brain tumors	13
Safety of JAK inhibitors: focus on cardiovascular and thromboembolic events	12
Avacopan for the treatment of ANCA-associated vasculitis	12
Novel insights into the pathogenesis of virus-induced ARDS: review on the central role of the epithelial-endothelial barrier	12
The role of interleukins in pathogenesis and prognosis of atrial fibrillation	12
Patient-centered approaches for patients with systemic autoimmune rheumatic diseases: development and evolution	12
CSE1L as a prognostic biomarker associated with pan cancer immune infiltration and drug sensitivity	12
Diagnostic accuracy of QuantiFERON-TB gold plus with chemiluminescence immunoassay: a systematic review and meta-analysis	12
Recent updates in the diagnosis and management of cryoglobulinemic vasculitis	12
Subcutaneous immunoglobulin 16.5% for the treatment of pediatric patients with primary antibody immunodeficiency	11
Advances in tumor immunotherapy targeting macrophages	11
Toward a personalized therapy of still’s disease based on immunologic endotypes: a narrative review	11
Temporal trends in anaphylaxis ED visits over the last decade and the effect of COVID-19 pandemic on these trends	11
Insights into the immunological links between dietary habits and asthma	11
At the cutting-edge: what’s the latest in imaging to diagnose Sjögren’s disease?	10
Glucocorticoid in systemic lupus erythematosus: the art beyond science	10
Current approaches for diagnosis of subclinical pulmonary tuberculosis, clinical implications and future perspectives: a scoping review	10
Letter to the editor regarding ‘perspective: diagnostic laboratories should urgently develop T cell assays for SARS-CoV-2 infection’	10
How does sleep influence asthma through immunity?	10
Definition of severity and treatment response in chronic rhinosinusitis with nasal polyps: a Delphi study among French experts	10
Pediatric IgG4-related disease: a descriptive review	10
Monoclonal antibodies in diabetic retinopathy	10
Immunology and targeted therapy in Castleman disease	10
Updates in toxicities associated with immune checkpoint inhibitors	10

Gut-brain communication in COVID-19: molecular mechanisms, mediators, biomarkers, and therapeutics	10
Genetic polymorphisms impacting clinical pharmacology of drugs used to treat inflammatory bowel disease: a precursor to multi-omics approach to precision medicine	10
Basophil activation test in the food allergy clinic: its current use and future applications	10
Antiphospholipid antibodies and the risk of adverse pregnancy outcomes in patients with systemic lupus erythematosus: a systematic review and meta-analysis	10
Harnessing the power of AI-based models to accelerate drug discovery against immune diseases	10
Interferon beta-1a sc at 25 years: a mainstay in the treatment of multiple sclerosis over the period of one generation	10
What place will tezepelumab hold in the treatment paradigm in chronic rhinosinusitis?	10
Peanut allergy: risk factors, immune mechanisms, and best practices for oral immunotherapy success	10
Guidance for stem cell therapy for juvenile systemic sclerosis patients	10
The interaction between innate immunity and oral microbiota in oral diseases	10
Skin infections during dupilumab monotherapy in moderate-to-severe atopic dermatitis – a meta-analysis of randomized clinical trials	10
Colorectal medullary carcinoma: a pathological subtype with intense immune response and potential to benefit from immune checkpoint inhibitors	9
The role of serological biomarkers in the diagnosis and management of autoimmune pancreatitis	9
Abdeg technology for the treatment of myasthenia gravis: efgartigimod drug experience	9
Update on virus-induced asthma exacerbations	9
The role of immune reconstitution in relapse after allogeneic hematopoietic stem cell transplantation	9
An update on VEXAS syndrome	9
Comparing available JAK inhibitors for treating patients with psoriasis	9
Budesonide delayed-release capsules to reduce proteinuria in adults with primary immunoglobulin A nephropathy	9
Tofacitinib for the treatment of active ankylosing spondylitis in adults	9
The (apparent) antibody paradox in COVID-19	9
Individual differences in response to dust-mite-allergen specific immunotherapy in allergic rhinitis: a meta-analysis of randomized controlled trials	9
An evaluation of anifrolumab for use in adults with systemic lupus erythematosus	9
Risk of infections in psoriasis: assessment and challenges in daily management	9
Hemophagocytic lymphohistiocytosis post chimeric antigen receptor T cell therapies	9
B cell depletion and inhibition in systemic lupus erythematosus	9
Immune dysfunction in inborn errors of immunity causing malignancies	9
Model-based computational precision medicine to develop combination therapies for autoimmune diseases	9
A review of disease burden and clinical management for generalized pustular psoriasis in China	9
Biomarkers for systemic lupus erythematosus – a focus on organ damage	8
The emerging role of IL-23 in asthma and its clinical implications	8
Evaluating topical JAK inhibitors as a treatment option for atopic dermatitis	8
Epstein–Barr virus-driven lymphoproliferation in inborn errors of immunity: a diagnostic and therapeutic challenge	8
The clinical role of anakinra in the armamentarium against familial Mediterranean fever	8
Update on real-world use of facilitated subcutaneous immunoglobulin and immune globulin subcutaneous (human) 20% solution in patients with immunodeficiencies: poster extracts from the 19th Biennial Me	8
Early diagnosis of systemic sclerosis, where do we stand today?	8
The role of PCSK9 in inflammation, immunity, and autoimmune diseases	8
How suitable is intravenous tocilizumab for the treatment of Graves’ ophthalmopathy?	8
Treatment controversies in spondyloarthritis and psoriatic arthritis: focus on biologics and targeted therapies	8
Systemic therapy in juvenile localized scleroderma	8
Treatment strategies for ANCA-associated vasculitides: from standard protocols to future horizons	8
Considerations for managing elderly patients with atopic dermatitis	8
Efgartigimod for generalized myasthenia gravis with or without anti-acetylcholine receptor antibodies: a worldwide and Japanese perspective	8
Characterizing the immune tumor microenvironment in ALK fusion-positive lung cancer: state-of-the-art and therapeutical implications	8
Role of tight junction proteins in shaping the immune milieu of malignancies	8
Interleukin 6 in diabetes, chronic kidney disease, and cardiovascular disease: mechanisms and therapeutic perspectives	8
In-vitro assays for immuno-oncology drug efficacy assessment and screening for personalized cancer therapy: scopes and challenges	7
Clinical and immunologic implication of neo-osteogenesis in chronic rhinosinusitis	7
The GLP-1 receptor in airway inflammation in asthma: a promising novel target?	7
An IPF-like disease course in disorders other than IPF: how can this be anticipated, recognized, and managed?	7
Lack of association between TNFA and TNFB polymorphisms and the risk of multiple sclerosis: a meta-analysis from 37 studies	7
The CD8+ T cell exhaustion mechanisms in chronic hepatitis B infection and immunotherapeutic strategies: a systematic review	7
Fatigue in ANCA-associated vasculitis (AAV) and systemic sclerosis (SSc): similarities with Myalgic encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS). A critical review of the literature	7
Cross-talk between immune cells and tumor cells in non-Hodgkin lymphomas arising in common variable immunodeficiency	7
Response to letter to the editor: Bradford Hill and breast implant illness: evidence for a causal association with breast implants	7
Enthesitis-related arthritis and spondylarthritis: the same disease or disparate entities?	7
Pharmacokinetics of a proposed tocilizumab biosimilar (MSB11456) versus US-licensed tocilizumab: results of a randomized, double-blind, single-intravenous dose study in healthy adults	7
The IL-4, IL-13 and IL-31 pathways in atopic dermatitis	7
Development of a method of nasal secretions sampling for local nasal inflammation studies	7
Non-anti TNFα biologic agents for noninfectious uveitis associated with systemic inflammatory diseases: a systematic review	7
Association between genetic variants in ZNF365 and inflammatory bowel disease risk in Caucasians: a meta-analysis and trial sequential analysis	7
Management and treatment optimization of patients with mild to moderate ulcerative colitis	7
The suitability of treating atopic dermatitis with Janus kinase inhibitors	7
A critical review of belumosudil in adult and pediatric patients with chronic graft-versus-host disease	7
Late effects following hematopoietic cell transplantation for severe combined immunodeficiency: critical factors and therapeutic options	7
The burden of mental health issues in Behçet’s disease: implications for patient quality of life	7
Cytokine alterations in psoriasis: an updated review	7
The role of systemic corticosteroids in severe asthma and new evidence in their management and tapering	7