OOIR: Observatory of International Research

Papers

(The TQCC of Expert Review of Clinical Immunology is 6. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-02-01 to 2025-02-01.)

Article	Citations
Utilizing type I interferon expression in the identification of antiphospholipid syndrome subsets	91
Assessing the EULAR/ACR classification criteria for patients with systemic lupus erythematosus	77
Biologicals for moderate-to-severe plaque type psoriasis in pediatric patients	76
The methylenetetrahydrofolate reductase 1298 A>C polymorphism is associated with an increased risk of inflammatory bowel disease: evidence from a meta-analysis	76
Managing acute COVID-19 in immunocompromised pediatric patients	63
Genetic syndromes and autoimmunity: what do we know? Focus on Down and Turner syndrome	58
Impact of immunotherapies on COVID-19 outcomes in multiple sclerosis patients	43
A review of current biomarkers in chronic rhinosinusitis with or without nasal polyps	42
The evolving role of JAK inhibitors in the treatment of inflammatory bowel disease	41
Ex vivo and in vivo T-cell depletion in allogeneic transplantation: towards less or non-cytotoxic conditioning regimens	40
Peanut (Arachis hypogaea) allergen powder-dnfp for the mitigation of allergic reactions to peanuts in children and adolescents	35
Predicting lupus low disease activity state and remission in SLE: novel insights	30
Abdeg technology for the treatment of myasthenia gravis: efgartigimod drug experience	28
Targeting the microbiome in Crohn’s disease	28
Responses of patients with juvenile idiopathic arthritis to methotrexate: a genomic outlook	27
A critical review of dupilumab for adult patients with prurigo nodularis	24
Precision medicine in the allergy clinic: the application of component resolved diagnosis	24
Evaluation of ruxolitinib cream 1.5% as an at-home therapy for repigmentation in non-segmental vitiligo	24
Broadening the clinical spectrum of giant cell arteritis: from the classic cranial to the predominantly extracranial pattern of the disease	24
Anoikis and SPP1 in idiopathic pulmonary fibrosis: integrating bioinformatics, cell, and animal studies to explore prognostic biomarkers and PI3K/AKT signaling regulation	23
Secukinumab for children and adolescents with enthesitis-related arthritis and psoriatic arthritis: lessons from treatment in adults and the way forward	22
Safety and efficacy of epicutaneous immunotherapy with DBV712 (peanut patch) in peanut allergy	22
Lymphocyte-C-reactive protein ratio combined with albumin upon admission predicts coronary artery dilation and aneurysm formation in pediatric patients with Kawasaki disease: a retrospective cohort st	22
How could our genetics impact COVID-19 vaccine response?	22
The role of immune reconstitution in relapse after allogeneic hematopoietic stem cell transplantation	21

Examining the autoimmune aspects of frontal fibrosing alopecia	20
Bradford Hill and breast implant illness: no evidence for causal association with breast implants	20
An immunologist’s guide to immunosenescence and its treatment	20
The Impact of Preeclampsia in Lupus Nephritis	20
Generalized pustular psoriasis: current management status and unmet medical needs in Japan	19
What is the full potential of baricitinib in treating patients with COVID-19?	18
Innovative treatments for severe uncontrolled chronic rhinosinusitis with nasal polyps	16
Cellular mechanisms and clinical applications for phenocopies of inborn errors of immunity: infectious susceptibility due to cytokine autoantibodies	16
BRAF inhibitors and their immunological effects in malignant melanoma	16
Challenges and management of childhood noninfectious chronic uveitis	16
An updated overview on celiac disease: from immuno-pathogenesis and immuno-genetics to therapeutic implications	16
Machine learning method for the cellular phenotyping of nasal polyps from multicentre tissue scans	16
Assessing the potential of epigenetic targets as biomarkers in the diagnosis and treatment of rheumatoid arthritis	15
A successful linkage of a named patient products of sublingual immunotherapy-dispensing registry to French healthcare insurance database (SNDS): methodological constitution of the EfficAPSI cohort	15
The multidisciplinary approach to diagnosing inborn errors of immunity: a comprehensive review of discipline-based manifestations	15
Telemedicine beyond the pandemic: challenges in the pediatric immunology clinic	15
The role of IL-6 and IL-6 blockade in COVID-19	15
Perspective: the nose and the stomach play a critical role in the NZACE2-Pātari* (modified ACE2) drug treatment project of SARS-CoV-2 infection	14
An updated review on Mendelian susceptibility to mycobacterial diseases– a silver jubilee celebration of its first genetic diagnosis	13
Tofacitinib for the treatment of active ankylosing spondylitis in adults	13
Colorectal medullary carcinoma: a pathological subtype with intense immune response and potential to benefit from immune checkpoint inhibitors	13
Prognostic factors for post-operative outcomes in chronic rhinosinusitis with nasal polyps: a systematic review	13
Vitamin D as disease-modifying therapy for multiple sclerosis?	13
Olfactory dysfunction in chronic rhinosinusitis: insights into the underlying mechanisms and treatments	13
Clinical updates in neoadjuvant immunotherapy for melanoma before surgery	13
A review of disease burden and clinical management for generalized pustular psoriasis in China	13
Immune dysfunction in inborn errors of immunity causing malignancies	13
A prospective single-arm study on the efficacy and safety of short-course oral corticosteroids followed by topical corticosteroids in patients with severe chronic rhinosinusitis with nasal polyps	13
Immunobiology and treatment of cutaneous T-cell lymphoma	13
Inducibility or predestination? Queries and concepts around drug-free remission in rheumatoid arthritis	13
Bimekizumab for the treatment of psoriatic arthritis	12
Will SARS-CoV-2 impact the incidence and nature of other respiratory infections?	12
Eosinophilic esophagitis: does age matter?	12
Efficacy of biologic agents for palmoplantar psoriasis: a systematic review and network meta-analysis	12
Aleukemic variant of T-cell large granular lymphocyte leukemia in patients with rheumatoid arthritis - diagnostically challenging subtype	12
Pan-cancer analysis of the prognostic significance of ACKR2 expression and the related genetic/epigenetic dysregulations	12
Molecular genotyping versus serological diagnosis for RH blood group typing in sickle cell patients	12
New therapeutic concepts against ischemia-reperfusion injury in organ transplantation	11
Model-based computational precision medicine to develop combination therapies for autoimmune diseases	11
The interleukin-1 family cytokines in psoriasis: pathogenetic role and therapeutic perspectives	11
Anifrolumab: first biologic approved in the EU not restricted to patients with a high degree of disease activity for the treatment of moderate to severe systemic lupus erythematosus	11
Pioglitazone as a potential modulator in autoimmune diseases: a review on its effects in systemic lupus erythematosus, psoriasis, inflammatory bowel disease, and multiple sclerosis	11
Update on virus-induced asthma exacerbations	11
Epinephrine treatment of food-induced and other cause anaphylaxis in United States and Canadian Emergency Departments: a systematic review and meta-analysis	11
Proportion of T follicular helper cells in peripheral blood of rheumatoid arthritis patients: a systematic review and meta-analysis	11
Growth differentiation factor-15 as an emerging biomarker for identifying myositis	10
An update on VEXAS syndrome	10
A critical evaluation of nemolizumab for prurigo nodularis	10
Efficacy and safety of subcutaneous immunotherapy with polymerized allergen mixtures in polyallergic patients – ARES observational study	10
Why do drug treatments fail in Sjögren’s disease? Considerations for treatment, trial design and interpretation of clinical efficacy	10

Biological drugs for the treatment of children with chronic spontaneous urticaria	10
Pharmacogenetics of childhood uncontrolled asthma	9
Novel insights into central compartment atopic disease - a literature review	9
Risk of infections in psoriasis: assessment and challenges in daily management	9
The role of fibroblast in chronic rhinosinusitis with nasal polyps: a key player in the inflammatory process	9
Managing psoriatic arthritis in different clinical scenarios	9
Machine learning approaches to improve disease management of patients with rheumatoid arthritis: review and future directions	9
Ruxolitinib as the first post-steroid treatment for acute and chronic graft-versus-host disease	9
Re-evaluation of nailfold capillaroscopy in discriminating primary from secondary Raynaud’s phenomenon and in predicting systemic sclerosis: a randomised observational prospective cohort study	8
Matrix metalloproteinases in chronic rhinosinusitis	8
How to and should we target EBV in MS?	8
The clinical role of anakinra in the armamentarium against familial Mediterranean fever	8
Intranasal corticosteroid and antihistamine combinations in the treatment of allergic rhinitis: the role of the novel formulation olopatadine/mometasone furoate	8
Antiphospholipid antibodies and osteonecrosis in systemic lupus erythematosus: a meta-analysis	8
The role of genetics in food allergy	8
More than a random association between chronic obstructive pulmonary disease and psoriatic arthritis: shared pathogenic features and implications for treatment	8
How should we approach management of childhood onset chronic anterior uveitis refractory to adalimumab?	8
Biologics for Hidradenitis suppurativa: evolution of the treatment paradigm	8
Could we co-opt the cannabinoid system for asthma therapy?	8
Filgotinib in rheumatoid arthritis	8
An evaluation of anifrolumab for use in adults with systemic lupus erythematosus	8
Systemic therapy in juvenile localized scleroderma	8
Upadacitinib for the treatment of adult patients with active psoriatic arthritis	8
Comparison of high- and low-molecular-weight sensitizing agents causing occupational asthma: an evidence-based insight	8
Corticosteroid-eluting implants for the management of chronic rhinosinusitis with or without nasal polyps	8
Predicting the risk of relapse in polymyalgia rheumatica: novel insights	8
Genetic variations in the human immune system influence susceptibility to tegumentary leishmaniasis: a systematic review and meta-analysis	8
Pharmacokinetics and pharmacodynamics of a proposed tocilizumab biosimilar MSB11456 versus both the US-licensed and EU-approved products: a randomized, double-blind trial	7
Voclosporin: a novel calcineurin inhibitor for the management of lupus nephritis	7
Circulating NT-proANP level is a predictor of mortality for systemic sclerosis: a retrospective study of an Italian cohort	7
Could small molecules be used in combination with biologics for inflammatory bowel disease?	7
How best to manage relapse and remission in ANCA-associated vasculitis	7
Dangerous liaisons? The role of inflammation and comorbidities in HIV and SARS-CoV-2 infection	7
The relationship between bullous pemphigoid and renal disease and related treatments: a review of the current literature	7
IRF1 expression might be a biomarker of CD8+ T cell infiltration in cutaneous melanoma	7
The (apparent) antibody paradox in COVID-19	7
How suitable is intravenous tocilizumab for the treatment of Graves’ ophthalmopathy?	7
Current evaluation and management of patients with chronic rhinosinusitis and nasal polyps	7
Mast cell activation: beyond histamine and tryptase	7
Pharmacoeconomics of allergy immunotherapy versus pharmacotherapy	7
Translational characterization of immune pathways in inflammatory bowel disease: insights for targeted treatments	7
Tapinarof cream for the topical treatment of plaque psoriasis in adults	7
Clinical guide to eosinophilic fasciitis: straddling dermatology and rheumatology	7
Optimizing the treatment of cytomegalovirus infection in allo-HSCT recipients	7
Pediatric chronic spontaneous urticaria: a brief clinician’s guide	7
Innovative cell therapies for systemic sclerosis: available evidence and new perspectives	7
The oft-overlooked cardiovascular complications of inflammatory bowel disease	7
Epstein–Barr virus-driven lymphoproliferation in inborn errors of immunity: a diagnostic and therapeutic challenge	6
Tumor-associated tertiary lymphoid structures in cancer: implications for immunotherapy	6
Tumor associated macrophages as key contributors and targets in current and future therapies for melanoma	6
Biomarkers guiding biological therapeutic strategies in chronic rhinosinusitis with nasal polyps: an emerging challenge	6
Machine learning and artificial intelligence within pediatric autoimmune diseases: applications, challenges, future perspective	6
Role of tight junction proteins in shaping the immune milieu of malignancies	6
Biomarkers of chronic spontaneous urticaria and their clinical implications	6
What are the prospects for antiplatelet agents for thromboprophylaxis in antiphospholipid syndrome?	6
Personalizing therapy selection in inflammatory bowel disease	6
Role of CD68 in the tumor immune microenvironment in Hodgkin’s lymphoma	6
Characterizing the immune tumor microenvironment in ALK fusion-positive lung cancer: state-of-the-art and therapeutical implications	6
Correction	6
An evaluation of the recently approved drugs for treating atopic dermatitis in the context of their safety and efficacy: a systematic review and meta-analysis	6
Pathogen-specific cell-mediated immunity to guide the management of cytomegalovirus in solid organ transplantation: state of the art clinical review	6
Improving prediction of disease outcome for inflammatory bowel disease: progress through systems medicine	6
Novel therapeutic approaches for cutaneous T cell lymphomas	6
Rationale for IL-37 as a novel therapeutic agent in inflammation	6
Treatment controversies in spondyloarthritis and psoriatic arthritis: focus on biologics and targeted therapies	6
What is the relevance of FoxP3 in the tumor microenvironment and cancer outcomes?	6
CAR-T cell technologies that interact with the tumour microenvironment in solid tumours	6
The effect of intense pulsed light combined with topical 0.05% Cyclosporin A eyedrops in the treatment of Sjögren’s syndrome related dry eye	6
Inflammatory bowel disease manifestations in spondyloarthritis: considerations for the clinician	6
Recent insights into the impacts of COVID-19 on pediatric asthma	6
Dupilumab in chronic rhinosinusitis with nasal polyposis: current status, challenges, and future perspectives	6
Food immunotherapy: current status and future needs	6