Expert Review of Clinical Immunology

Article	Citations
How could our genetics impact COVID-19 vaccine response?	92
Bradford Hill and breast implant illness: no evidence for causal association with breast implants	78
Full consideration of the pollen exposure effect in clinical trial design for pollen-induced allergic rhinitis	71
Will SARS-CoV-2 impact the incidence and nature of other respiratory infections?	65
Pan-cancer analysis of the prognostic significance of ACKR2 expression and the related genetic/epigenetic dysregulations	64
The multidisciplinary approach to diagnosing inborn errors of immunity: a comprehensive review of discipline-based manifestations	52
Pioglitazone as a potential modulator in autoimmune diseases: a review on its effects in systemic lupus erythematosus, psoriasis, inflammatory bowel disease, and multiple sclerosis	48
A critical review of dupilumab for adult patients with prurigo nodularis	44
Aleukemic variant of T-cell large granular lymphocyte leukemia in patients with rheumatoid arthritis - diagnostically challenging subtype	40
Immunobiology and treatment of cutaneous T-cell lymphoma	38
A prospective single-arm study on the efficacy and safety of short-course oral corticosteroids followed by topical corticosteroids in patients with severe chronic rhinosinusitis with nasal polyps	36
The therapeutic effect of mRNA vaccines in glioma: a comprehensive review	33
Bimekizumab for the treatment of psoriatic arthritis	32
Ruxolitinib as the first post-steroid treatment for acute and chronic graft-versus-host disease	31
Re-evaluation of nailfold capillaroscopy in discriminating primary from secondary Raynaud’s phenomenon and in predicting systemic sclerosis: a randomised observational prospective cohort study	30
Differential risk of autoimmune disorders in non-traumatic osteonecrosis: clue to pathogenesis	29
Pathogen-specific cell-mediated immunity to guide the management of cytomegalovirus in solid organ transplantation: state of the art clinical review	27
How to and should we target EBV in MS?	27
Dupilumab in chronic rhinosinusitis with nasal polyposis: current status, challenges, and future perspectives	26
IRF1 expression might be a biomarker of CD8+ T cell infiltration in cutaneous melanoma	24
Food immunotherapy: current status and future needs	23
The effect of intense pulsed light combined with topical 0.05% Cyclosporin A eyedrops in the treatment of Sjögren’s syndrome related dry eye	23
Biomarkers guiding biological therapeutic strategies in chronic rhinosinusitis with nasal polyps: an emerging challenge	22
More than a random association between chronic obstructive pulmonary disease and psoriatic arthritis: shared pathogenic features and implications for treatment	22
Advances in therapeutic targeting of immune checkpoints receptors within the CD96-TIGIT axis: clinical implications and future perspectives	21

Rare forms of inflammatory myopathies – part I, generalized forms	21
Emergence of an adaptive immune paradigm to explain celiac disease: a perspective on new evidence and implications for future interventions and diagnosis	20
Impact of anti-PD1 immunotherapy and circulating tumor cells on progression-free survival in surgical pancreatic adenocarcinoma: a retrospective cohort study	20
An exercise immune fitness test to unravel mechanisms of Post-Acute Sequelae of COVID-19	20
Durability and long-term outcomes of biologic therapies in psoriasis	19
Transcriptional regulation of B cell class-switch recombination: the role in development of noninfectious complications	19
Evaluating the use of JAK inhibitors in inflammatory connective tissue diseases in pediatric patients: an update	18
Direct economic burden 1 year postoperation in Chinese adult patients with chronic rhinosinusitis with nasal polyps	18
Classification and management strategies for paediatric chronic nonbacterial osteomyelitis and chronic recurrent multifocal osteomyelitis	18
How do nuclear factor kappa B (NF-κB)1 and NF-κB2 defects lead to the incidence of clinical and immunological manifestations of inborn errors of immunity?	18
Pharmacokinetics and tolerability of prefilled syringe and auto-injector presentations of MSB11456: results of a randomized, single-dose study in healthy adults	18
Recent insights into the pathogenesis of autoimmune hypophysitis	17
Neurological adverse effects of chimeric antigen receptor T-cell therapy	16
Current treatment options and long-term outcomes in patients with eosinophilic esophagitis	16
Gut immune homeostasis: the immunomodulatory role of Bacillus clausii, from basic to clinical evidence	15
Transcriptomic observations of intra and extracellular immunotherapy targets for pediatric brain tumors	15
CSE1L as a prognostic biomarker associated with pan cancer immune infiltration and drug sensitivity	15
Pathophysiology and management of Staphylococcus aureus in nasal polyp disease	15
Sicca syndrome/Sjögren’s disease associated with cancer immunotherapy: a narrative review on clinical presentation, biomarkers, and management	15
The role of interleukins in pathogenesis and prognosis of atrial fibrillation	15
T-lymphocyte depleted transplants for inborn errors of immunity	15
Inflammatory myopathy in adults, health-related quality of life, and wellbeing: a round trip between immune disease and wellness	15
Chronic obstructive pulmonary disease, biological agents and small molecules: where do we stand?	14
Safety of JAK inhibitors: focus on cardiovascular and thromboembolic events	14
The functional role and the clinical application of periostin in chronic rhinosinusitis	14
Immune mechanisms, the role of complement, and related therapies in autoimmune neuropathies	14
Recent insights into comorbidities in atopic dermatitis	14
An updated evaluation of avatrombopag for the treatment of chronic immune thrombocytopenia	13
Toward a personalized therapy of still’s disease based on immunologic endotypes: a narrative review	13
Diagnostic accuracy of QuantiFERON-TB gold plus with chemiluminescence immunoassay: a systematic review and meta-analysis	13
Eradicating measurable residual disease via immunotherapy to cure acute lymphoblastic leukemia: current status and future directions	13
Patient-centered approaches for patients with systemic autoimmune rheumatic diseases: development and evolution	13
Peanut allergy: risk factors, immune mechanisms, and best practices for oral immunotherapy success	13
IL-17A in psoriatic arthritis: mechanistic insights, clinical implications, and advances in therapeutic strategies	13
Advancements in immunotherapy for advanced esophageal squamous cell carcinoma: a comprehensive review of current strategies and future directions	13
Insights into the immunological links between dietary habits and asthma	13
Subcutaneous immunoglobulin 16.5% for the treatment of pediatric patients with primary antibody immunodeficiency	13
Challenges in uncontrolled asthma in pediatrics: important considerations for the clinician	13
Updates in toxicities associated with immune checkpoint inhibitors	12
Monoclonal antibodies in diabetic retinopathy	12
Temporal trends in anaphylaxis ED visits over the last decade and the effect of COVID-19 pandemic on these trends	12
Glucocorticoid in systemic lupus erythematosus: the art beyond science	12
Interferon beta-1a sc at 25 years: a mainstay in the treatment of multiple sclerosis over the period of one generation	12
At the cutting-edge: what’s the latest in imaging to diagnose Sjögren’s disease?	12
Advances in tumor immunotherapy targeting macrophages	12
Recent updates in the diagnosis and management of cryoglobulinemic vasculitis	12
Harnessing the power of AI-based models to accelerate drug discovery against immune diseases	12
Induction of aquaporins by plasma of patients with systemic lupus erythematosus	11
How does sleep influence asthma through immunity?	11
The role of serological biomarkers in the diagnosis and management of autoimmune pancreatitis	11

The interaction between innate immunity and oral microbiota in oral diseases	11
Budesonide delayed-release capsules to reduce proteinuria in adults with primary immunoglobulin A nephropathy	11
What place will tezepelumab hold in the treatment paradigm in chronic rhinosinusitis?	11
Letter to the editor regarding ‘perspective: diagnostic laboratories should urgently develop T cell assays for SARS-CoV-2 infection’	11
Antiphospholipid antibodies and the risk of adverse pregnancy outcomes in patients with systemic lupus erythematosus: a systematic review and meta-analysis	11
Skin infections during dupilumab monotherapy in moderate-to-severe atopic dermatitis – a meta-analysis of randomized clinical trials	11
Basophil activation test in the food allergy clinic: its current use and future applications	10
B cell depletion and inhibition in systemic lupus erythematosus	10
Colorectal medullary carcinoma: a pathological subtype with intense immune response and potential to benefit from immune checkpoint inhibitors	10
Current approaches for diagnosis of subclinical pulmonary tuberculosis, clinical implications and future perspectives: a scoping review	10
Guidance for stem cell therapy for juvenile systemic sclerosis patients	10
Definition of severity and treatment response in chronic rhinosinusitis with nasal polyps: a Delphi study among French experts	10
Hemophagocytic lymphohistiocytosis post chimeric antigen receptor T cell therapies	10
Immunology and targeted therapy in Castleman disease	10
Gut-brain communication in COVID-19: molecular mechanisms, mediators, biomarkers, and therapeutics	10
Genetic polymorphisms impacting clinical pharmacology of drugs used to treat inflammatory bowel disease: a precursor to multi-omics approach to precision medicine	10
Phosphoinositide-3-kinase δ as an immune check-pathway in cancer Immunology. Therapeutic prospects	10
Comparing available JAK inhibitors for treating patients with psoriasis	10
Pediatric IgG4-related disease: a descriptive review	10
A review of disease burden and clinical management for generalized pustular psoriasis in China	9
Model-based computational precision medicine to develop combination therapies for autoimmune diseases	9
An evaluation of anifrolumab for use in adults with systemic lupus erythematosus	9
Role of tight junction proteins in shaping the immune milieu of malignancies	9
The (apparent) antibody paradox in COVID-19	9
The role of immune reconstitution in relapse after allogeneic hematopoietic stem cell transplantation	9
Update on virus-induced asthma exacerbations	9
Individual differences in response to dust-mite-allergen specific immunotherapy in allergic rhinitis: a meta-analysis of randomized controlled trials	9
Characterizing the immune tumor microenvironment in ALK fusion-positive lung cancer: state-of-the-art and therapeutical implications	9
Vascular endothelial dysfunction in pediatric rheumatic diseases: a systematic review and meta-analysis	9
Systemic therapy in juvenile localized scleroderma	9
Abdeg technology for the treatment of myasthenia gravis: efgartigimod drug experience	9
Tofacitinib for the treatment of active ankylosing spondylitis in adults	9
An update on VEXAS syndrome	9
Risk of infections in psoriasis: assessment and challenges in daily management	9
How suitable is intravenous tocilizumab for the treatment of Graves’ ophthalmopathy?	9
Epstein–Barr virus-driven lymphoproliferation in inborn errors of immunity: a diagnostic and therapeutic challenge	9
Dysautonomia in systemic lupus erythematosus: when to suspect and how to investigate	9
Advancing kidney protection in type 1 diabetes: insights from emerging therapies in type 2 diabetes and chronic kidney disease	8
The clinical role of anakinra in the armamentarium against familial Mediterranean fever	8
Management and treatment optimization of patients with mild to moderate ulcerative colitis	8
The emerging role of IL-23 in asthma and its clinical implications	8
Response to letter to the editor: Bradford Hill and breast implant illness: evidence for a causal association with breast implants	8
Considerations for managing elderly patients with atopic dermatitis	8
Early diagnosis of systemic sclerosis, where do we stand today?	8
Interleukin 6 in diabetes, chronic kidney disease, and cardiovascular disease: mechanisms and therapeutic perspectives	8
Efgartigimod for generalized myasthenia gravis with or without anti-acetylcholine receptor antibodies: a worldwide and Japanese perspective	8
The role of PCSK9 in inflammation, immunity, and autoimmune diseases	8
Treatment strategies for ANCA-associated vasculitides: from standard protocols to future horizons	8
The relationship between interleukin 17A rs2275913 gene polymorphism and circulating IL17A levels and disease activity and severity in Egyptian rheumatoid arthritis patients	8
Treatment controversies in spondyloarthritis and psoriatic arthritis: focus on biologics and targeted therapies	8
Mechanisms and therapeutic potential of epithelial-immune crosstalk in airway inflammation	8
Evaluating topical JAK inhibitors as a treatment option for atopic dermatitis	8
Biomarkers for systemic lupus erythematosus – a focus on organ damage	8
Pharmacokinetics of a proposed tocilizumab biosimilar (MSB11456) versus US-licensed tocilizumab: results of a randomized, double-blind, single-intravenous dose study in healthy adults	7
The role of systemic corticosteroids in severe asthma and new evidence in their management and tapering	7
Cross-talk between immune cells and tumor cells in non-Hodgkin lymphomas arising in common variable immunodeficiency	7
The CD8+ T cell exhaustion mechanisms in chronic hepatitis B infection and immunotherapeutic strategies: a systematic review	7
In-vitro assays for immuno-oncology drug efficacy assessment and screening for personalized cancer therapy: scopes and challenges	7
A critical review of belumosudil in adult and pediatric patients with chronic graft-versus-host disease	7
The GLP-1 receptor in airway inflammation in asthma: a promising novel target?	7
Clinical and immunologic implication of neo-osteogenesis in chronic rhinosinusitis	7
An IPF-like disease course in disorders other than IPF: how can this be anticipated, recognized, and managed?	7
Evaluating the role of lung ultrasound in the diagnosis of rheumatoid arthritis-interstitial lung disease	7
Development of a method of nasal secretions sampling for local nasal inflammation studies	7
Factors that influence infliximab biosimilar trough levels in the pediatric inflammatory bowel disease population	7
Potential interactions between STING pathway and the complement system in immune regulation	7
The suitability of treating atopic dermatitis with Janus kinase inhibitors	7
Late effects following hematopoietic cell transplantation for severe combined immunodeficiency: critical factors and therapeutic options	7
Multiple sclerosis-like manifestations in systemic autoimmune and inflammatory disorders: an update	7
Fatigue in ANCA-associated vasculitis (AAV) and systemic sclerosis (SSc): similarities with Myalgic encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS). A critical review of the literature	7
Lack of association between TNFA and TNFB polymorphisms and the risk of multiple sclerosis: a meta-analysis from 37 studies	7
Cytokine alterations in psoriasis: an updated review	7
Enthesitis-related arthritis and spondylarthritis: the same disease or disparate entities?	7
AQP9 weakens the cytotoxicity of CD8 + T cells in colon adenocarcinoma by boosting M2 polarization of macrophages under hypoxia conditions	7
IL-10: the master immunomodulatory cytokine in allergen immunotherapy	6
Comparative efficacy of systemic treatments for atopic dermatitis in adults	6
The burden of mental health issues in Behçet’s disease: implications for patient quality of life	6
COVID-19 and chronic rhinosinusitis: management and comorbidity – what have we learned?	6
A review of current biomarkers in chronic rhinosinusitis with or without nasal polyps	6
Genetic syndromes and autoimmunity: what do we know? Focus on Down and Turner syndrome	6

Broadening the clinical spectrum of giant cell arteritis: from the classic cranial to the predominantly extracranial pattern of the disease	6
Assessing the potential of epigenetic targets as biomarkers in the diagnosis and treatment of rheumatoid arthritis	6
Thyroid eye disease in the biologic era: a 40-year paradigm shift in nonsurgical therapeutic strategies	6
Comorbid allergic rhinitis and asthma: important clinical considerations	6
Non-anti TNFα biologic agents for noninfectious uveitis associated with systemic inflammatory diseases: a systematic review	6
Is post-COVID syndrome an autoimmune disease?	6
Growth differentiation factor-15 as an emerging biomarker for identifying myositis	6
Inflammation resolution and specialized pro-resolving lipid mediators in chronic rhinosinusitis	6
The methylenetetrahydrofolate reductase 1298 A>C polymorphism is associated with an increased risk of inflammatory bowel disease: evidence from a meta-analysis	6
Anifrolumab: first biologic approved in the EU not restricted to patients with a high degree of disease activity for the treatment of moderate to severe systemic lupus erythematosus	6
Managing acute COVID-19 in immunocompromised pediatric patients	6
What is the full potential of baricitinib in treating patients with COVID-19?	6
Why does malaise/fatigue occur? Underlying mechanisms and potential relevance to treatments in rheumatoid arthritis	6
Colchicine: protection of the brain beyond the heart?	6
Resveratrol: immunological activity and possible application in children and adolescents with allergic rhinitis	6
The pathophysiology of MASLD: an immunometabolic perspective	6
Innovative treatments for severe uncontrolled chronic rhinosinusitis with nasal polyps	6
Recent issues in JAK inhibitor safety: perspective for the clinician	6
An updated review on Mendelian susceptibility to mycobacterial diseases– a silver jubilee celebration of its first genetic diagnosis	6
Re-envisioning clinical trial design in systemic sclerosis	6
Telemedicine beyond the pandemic: challenges in the pediatric immunology clinic	6
Ex vivo and in vivo T-cell depletion in allogeneic transplantation: towards less or non-cytotoxic conditioning regimens	6
Unmet needs in the management of giant cell arteritis and polymyalgia rheumatica	6
5 reasons to encourage anti-SARS-CoV-2 vaccination in patients with rheumatic diseases	5
Balancing risks and benefits in the use of hydroxychloroquine and glucocorticoids in systemic lupus erythematosus	5
Overcoming the challenges of primary resistance and relapse after CAR-T cell therapy	5
Subcutaneous immunoglobulin 20% (Ig20Gly) treatment regimens in pediatric patients with primary immunodeficiencies – real-world data from the IG TATRY study	5
A critical review of halobetasol propionate foam (0.05%) as a treatment option for adolescent plaque psoriasis	5
Personalizing therapy selection in inflammatory bowel disease	5
CAR-T cell technologies that interact with the tumour microenvironment in solid tumours	5
The evolving role of JAK inhibitors in the treatment of inflammatory bowel disease	5
Olfactory dysfunction in chronic rhinosinusitis: insights into the underlying mechanisms and treatments	5
The oft-overlooked cardiovascular complications of inflammatory bowel disease	5
Neuro-ophthalmic challenges and multi-morbidity in vasculitis among the older adults	5
Epithelial cell dysfunction in chronic rhinosinusitis: the epithelial–mesenchymal transition	5
The role of complement and complement therapeutics in neuromyelitis optica spectrum disorders	5
Probiotics in asthma management: fiction or truth?	5
Clinical guide to eosinophilic fasciitis: straddling dermatology and rheumatology	5
Tumor-associated tertiary lymphoid structures in cancer: implications for immunotherapy	5
An evaluation of the recently approved drugs for treating atopic dermatitis in the context of their safety and efficacy: a systematic review and meta-analysis	5
Machine learning approaches to improve disease management of patients with rheumatoid arthritis: review and future directions	5
Recent insights into the impacts of COVID-19 on pediatric asthma	5
Biologics for chronic spontaneous urticaria: toward a personalized treatment	5
Conventional and new immunotherapies for immune system dysregulation in postpartum mood disorders: comparisons to immune system dysregulations in bipolar disorder, major depression, and postpartum aut	5
Presentation and diagnosis of autoimmune lymphoproliferative syndrome (ALPS)	5
Innovative surgical approaches for chronic rhinitis: nasal neurectomy mechanisms, techniques, and clinical outcomes	5
What is the relevance of FoxP3 in the tumor microenvironment and cancer outcomes?	5
Pharmacokinetics and pharmacodynamics of a proposed tocilizumab biosimilar MSB11456 versus both the US-licensed and EU-approved products: a randomized, double-blind trial	5
Correction	5
Ofatumumab subcutaneous injection for the treatment of relapsing forms of multiple sclerosis	5
Single-cell RNA sequencing: an emerging tool revealing dysregulated innate and adaptive immune response at single cell level in Kawasaki disease	4
Avacopan for the treatment of ANCA-associated vasculitis: an update	4
Gut inflammation in CVID: causes and consequences	4
Spectrum of neurological manifestations, existence of diabetes mellitus, and 5-year mortality and cancer association outcomes in a cohort of Omani patients with positive anti- GAD autoimmunity	4
Combination immunotherapy for pancreatic cancer: challenges and future considerations	4
Genes vs environment in inflammatory bowel disease: an update	4
Connecting salivary gland inflammation to specific symptoms in Sjögren’s disease	4
Update on the pathophysiology and treatment of diabetic kidney disease: a narrative review	4
Linking stress and inflammation – is there a missing piece in the puzzle?	4
New discoveries in the genetics and genomics of systemic juvenile idiopathic arthritis	4
An update on biologic treatments for neuromyelitis optica spectrum disorder	4
Therapeutic potential of JAK inhibitors in juvenile idiopathic arthritis-associated uveitis	4
Can we identify patients at risk of severe reactions to food?	4
Upadacitinib for moderate-to-severe atopic dermatitis, in adults and adolescents 12 years and older: review of international and Japanese populations	4
A review of berotralstat for the treatment of hereditary angioedema	4
Chronic rhinosinusitis disease control: a review of the history and the evidence	4
Exploring the relationship between house dust mites and asthma	4
Comparing treatment options for large vessel vasculitis	4
Janus kinase versus TNF inhibitors: where we stand today in rheumatoid arthritis	4
Diagnosis and management of systemic sclerosis-related calcinosis	4
Translational impact of omics studies in alopecia areata: recent advances and future perspectives	4
The complex relationship between large granular lymphocyte leukemia and rheumatic disease	4
Upadacitinib for the treatment of adults with active non-radiographic axial spondyloarthritis (nr-axSpA)	4
Evaluation of switching or simultaneous use of biologic treatment in patients with severe chronic rhinosinusitis with nasal polyps and severe asthma. Considerations in clinical decision making	4
Behçet disease: epidemiology, classification criteria and treatment modalities	4
Exploring treatment options for pediatric refractory chronic urticaria	4
Preventing fibrosis in IBD: update on immune pathways and clinical strategies	4
Future biomarkers for acute graft-versus-host disease: potential roles of nucleic acids, metabolites, and immune cell markers	3
SLE criteria are by necessity still based on clinical (and immunological) criteria items	3
Diagnosis and clinical management of Wiskott–Aldrich syndrome: current and emerging techniques	3
Immune pathways, current and potential therapies in Mycosis fungoides and Sezary syndrome	3
Tumor associated macrophages as key contributors and targets in current and future therapies for melanoma	3
Optimizing the treatment of cytomegalovirus infection in allo-HSCT recipients	3
Correction	3
Exploring allergy to novel foods in the Western countries: current and future perspectives	3
Immune signatures, testing, and management of febrile neutropenia in pediatric cancer patients	3
Autoimmune hemolytic anemia: causes and consequences	3
How should we approach management of childhood onset chronic anterior uveitis refractory to adalimumab?	3
Ten clinical conundrums in the management of eosinophilic granulomatosis with polyangiitis	3
Patch testing while immunosuppressed: potential risks and benefits	3
Correction	3
How suitable are JAK inhibitors in treating the inflammatory component in patients with alopecia areata and vitiligo?	3
Role of CD68 in the tumor immune microenvironment in Hodgkin’s lymphoma	3
Rationale for IL-37 as a novel therapeutic agent in inflammation	3
Filgotinib in rheumatoid arthritis	3