Expert Review of Clinical Immunology

Article	Citations
Immune-epidemiological parameters of the novel coronavirus – a perspective	145
Natural history of COVID-19 and therapeutic options	94
Diagnosis & management of alpha-gal syndrome: lessons from 2,500 patients	81
Global systematic review of primary immunodeficiency registries	73
A comparative review of immunoassays for COVID-19 detection	69
Circulating Calprotectin as a Biomarker of COVID-19 Severity	68
The IL-4, IL-13 and IL-31 pathways in atopic dermatitis	61
The role of IL-6 and IL-6 blockade in COVID-19	58
Swinging the pendulum: lessons learned from public discourse concerning hydroxychloroquine and COVID-19	54
SARS-COV-2-related immune-inflammatory thyroid disorders: facts and perspectives	49
Update on pollen-food allergy syndrome	46
Systemic lupus erythematosus and risk of infection	44
Breast implant illness: scientific evidence of its existence	43
Early-life exposure to air pollution and childhood allergic diseases: an update on the link and its implications	39
Atopic phenotypes and their implication in the atopic march	33
The role of Epstein-Barr virus in the etiology of multiple sclerosis: a current review	27
Ataxia-telangiectasia: epidemiology, pathogenesis, clinical phenotype, diagnosis, prognosis and management	26
Revisiting the complement system in systemic lupus erythematosus	25
The emerging role of type 2 inflammation in asthma	25
Epidemiology of rheumatoid arthritis: genetic and environmental influences	24
Perspective: diagnostic laboratories should urgently develop T cell assays for SARS-CoV-2 infection	24
Role of complement, anti-complement therapeutics, and other targeted immunotherapies in myasthenia gravis	24
Guselkumab: the First Selective IL-23 Inhibitor for Active Psoriatic Arthritis in Adults	24
Generalized pustular psoriasis: current management status and unmet medical needs in Japan	23
Cancer risk in patients with psoriasis: should we be paying more attention?	22

Coronavirus disease 2019: investigational therapies in the prevention and treatment of hyperinflammation	22
New insights into the progression from cutaneous lupus to systemic lupus erythematosus	22
JAK inhibitors, psoriatic arthritis, and axial spondyloarthritis: a critical review of clinical trials	21
Gut microbiota in Celiac Disease: microbes, metabolites, pathways and therapeutics	21
Abrocitinib for the treatment of atopic dermatitis	21
Generalized pustular psoriasis is a disease distinct from psoriasis vulgaris: evidence and expert opinion	20
Autoimmunity in common variable immunodeficiency: a systematic review and meta-analysis	20
Efficacy and safety of Tocilizumab in severe and critical COVID-19: A Systematic Review and Meta-Analysis	20
Interleukin 6 in diabetes, chronic kidney disease, and cardiovascular disease: mechanisms and therapeutic perspectives	20
The infection risks of JAK inhibition	20
Pathological mechanisms of abnormal iron metabolism and mitochondrial dysfunction in systemic lupus erythematosus	20
Stevens-Johnson syndrome and toxic epidermal necrolysis: risk factors, causality assessment and potential prevention strategies	19
Mechanical ventilation in Guillain–Barré syndrome	19
Emerging therapy options for IgG4-related disease	18
The pathogenic oral–gut–liver axis: new understandings and clinical implications	18
Calcipotriol/betamethasone dipropionate formulations for psoriasis: an overview of the options and efficacy data	18
Metabolic Syndrome and psoriatic arthritis: considerations for the clinician	18
An update on VEXAS syndrome	18
Rheumatoid arthritis related interstitial lung disease	17
Complement in autoimmune inflammatory myopathies, the role of myositis-associated antibodies, COVID-19 associations, and muscle amyloid deposits	17
Is post-COVID syndrome an autoimmune disease?	17
Multimorbidity and comorbidity in psoriatic arthritis – a perspective	17
Safety of JAK inhibitors: focus on cardiovascular and thromboembolic events	17
TNF-α inhibitors biosimilars as first line systemic treatment for moderate-to-severe chronic plaque psoriasis	17
Therapeutic targeting of the IL-13 pathway in skin inflammation	16
Impact of resolvin mediators in the immunopathology of diabetes and wound healing	15
The current status of biological treatment for uveitis	15
Ruxolitinib for the treatment of graft-versus-host disease	15
Elimination diets for eosinophilic esophagitis: making the best choice	15
The role of PCSK9 in inflammation, immunity, and autoimmune diseases	15
An immunologist’s guide to immunosenescence and its treatment	15
Germline IKZF1 mutations and their impact on immunity: IKAROS-associated diseases and pathophysiology	15
A 2020 update on the use of genetic testing for patients with primary immunodeficiency	15
HMGB1 in nasal inflammatory diseases: a reappraisal 30 years after its discovery	14
Gut inflammation in CVID: causes and consequences	14
Clinical management of patients with primary immunodeficiencies during the COVID-19 pandemic	14
Emerging therapies for ulcerative colitis	14
Clinical, immunological, and genetic features in 938 patients with autoimmune polyendocrinopathy candidiasis ectodermal dystrophy (APECED): a systematic review	14
A systematic review and meta-analysis of the association between the neutrophil, lymphocyte, and platelet count, neutrophil-to-lymphocyte ratio, and platelet-to-lymphocyte ratio and COVID-19 progressi	14
Efficacy and safety of subcutaneous infliximab versus adalimumab, etanercept and intravenous infliximab in patients with rheumatoid arthritis: a systematic literature review and meta-analysis	14
Biomarkers of chronic spontaneous urticaria and their clinical implications	13
Tofacitinib for the treatment of active ankylosing spondylitis in adults	13
Glucocorticoids in rheumatoid arthritis still on first line: the reasons	13
The clinical implications of the microbiome in the development of allergy diseases	12
Chimeric antigen receptor T-cell therapy for melanoma	12
Comorbid allergic rhinitis and asthma: important clinical considerations	12
The interleukin-1 family cytokines in psoriasis: pathogenetic role and therapeutic perspectives	12
Autoimmune hemolytic anemia: causes and consequences	12
Allergic contact dermatitis in children	11
Gut immune homeostasis: the immunomodulatory role of Bacillus clausii, from basic to clinical evidence	11

Myosin light chain kinase regulates intestinal permeability of mucosal homeostasis in Crohn’s disease	11
Recent issues in JAK inhibitor safety: perspective for the clinician	11
The wide spectrum of Kawasaki-like disease associated with SARS-CoV-2 infection	11
Dupilumab for the treatment of adolescents with atopic dermatitis	11
Nanoparticle-based immunotherapy: state of the art and future perspectives	11
Assessing and mitigating risk of infection in patients with multiple sclerosis on disease modifying treatment	11
Affecting the effectors: JAK inhibitors modulation of immune cell numbers and functions in patients with rheumatoid arthritis	11
Machine learning approaches to improve disease management of patients with rheumatoid arthritis: review and future directions	11
New frontiers in precision medicine for Sjogren’s syndrome	10
Severe COVID-19 is a T cell immune dysregulatory disorder triggered by SARS-CoV-2	10
Convalescent plasma and hyperimmune globulin therapy in COVID-19	10
Heterogeneity in myasthenia gravis: considerations for disease management	10
Pathogenesis and treatment of idiopathic and rheumatoid arthritis-related interstitial pneumonia. The possible lesson from COVID-19 pneumonia	10
Novel biomarkers for prediction of outcome and therapeutic response in juvenile idiopathic arthritis	10
Avacopan for the treatment of ANCA-associated vasculitis	10
Presentation and diagnosis of autoimmune lymphoproliferative syndrome (ALPS)	10
A systematic literature review of the effects of immunoglobulin replacement therapy on the burden of secondary immunodeficiency diseases associated with hematological malignancies and stem cell transp	10
Diagnosis and management of hypersensitivity reactions to vaccines	10
Evaluating topical JAK inhibitors as a treatment option for atopic dermatitis	10
Treatment of neuropsychiatric systemic lupus erythematosus: clinical challenges and future perspectives	10
Current concepts underlying the pathophysiology of acute Charcot neuroarthropathy in the diabetic foot and ankle	10
Perspective: the nose and the stomach play a critical role in the NZACE2-Pātari* (modified ACE2) drug treatment project of SARS-CoV-2 infection	10
Palindromic rheumatism: a unique and enigmatic entity with a complex relationship with rheumatoid arthritis	9
Diagnosis and treatment of non-allergic rhinitis: focus on immunologic mechanisms	9
Immune checkpoint inhibitor-induced inflammatory arthritis: identification and management	9
Clinical relevance of T follicular helper cells in systemic lupus erythematosus	9
Challenges in uncontrolled asthma in pediatrics: important considerations for the clinician	9
An updated overview on celiac disease: from immuno-pathogenesis and immuno-genetics to therapeutic implications	9
In search of pathobiological endotypes: a systems approach to early rheumatoid arthritis	9
A new case of congenital ficolin-3 deficiency with primary immunodeficiency	9
Autism spectrum disorders and natural killer cells: a review on pathogenesis and treatment	9
Ixekizumab for the treatment of ankylosing spondylitis	9
Comparing available JAK inhibitors for treating patients with psoriasis	9
Janus kinase versus TNF inhibitors: where we stand today in rheumatoid arthritis	8
Biologics and atherosclerotic cardiovascular risk in rheumatoid arthritis: a review of evidence and mechanistic insights	8
Assessing the EULAR/ACR classification criteria for patients with systemic lupus erythematosus	8
Hematopoietic stem cell transplantation in systemic autoinflammatory diseases - the first one hundred transplanted patients	8
Chimeric antigen receptor T cell therapy for pediatric and young adult B cell acute lymphoblastic leukemia	8
Chronic rhinosinusitis with nasal polyps: mechanistic insights from targeting IL-4 and IL-13 via IL-4Rα inhibition with dupilumab	8
Model-based computational precision medicine to develop combination therapies for autoimmune diseases	8
Regulation of crystal induced inflammation: current understandings and clinical implications	8
Clinical management of patients with rheumatoid arthritis during the COVID-19 pandemic	8
Personalized medicine in rheumatic diseases: how close are we to being able to use genetic biomarkers to predict response to TNF inhibitors?	8
Food allergy severity prediction: quite a way to go yet?	8
Comparing treatment options for large vessel vasculitis	7
Diagnostic and prognostic markers and treatment of connective tissue disease-associated pulmonary arterial hypertension: current recommendations and recent advances	7
Diagnosis and clinical management of Wiskott–Aldrich syndrome: current and emerging techniques	7
Oral immunotherapy for food allergy in children: is it worth it?	7
Pharmacoeconomics of allergy immunotherapy versus pharmacotherapy	7
An updated review on Mendelian susceptibility to mycobacterial diseases– a silver jubilee celebration of its first genetic diagnosis	7
Cancer risk in systemic sclerosis: identifying risk and managing high-risk patients	7
Treatment of inflammatory complications in common variable immunodeficiency (CVID): current concepts and future perspectives	7
Advances in therapeutic targeting of immune checkpoints receptors within the CD96-TIGIT axis: clinical implications and future perspectives	7
Predicting lupus flares: epidemiological and disease related risk factors	7
Pharmacokinetics and pharmacodynamics of a proposed tocilizumab biosimilar MSB11456 versus both the US-licensed and EU-approved products: a randomized, double-blind trial	7
Discontinuation of immunoglobulin replacement therapy in patients with secondary antibody deficiency	7
DEL-1: a potential therapeutic target in inflammatory and autoimmune disease?	7
Current treatment options and long-term outcomes in patients with eosinophilic esophagitis	7
Serum exosomal long noncoding RNA nuclear-enriched abundant transcript 1 predicts 90-day mortality in acute-on-chronic hepatitis B liver failure	7
A systematic review and meta-analysis of the gonadotoxic effects of cyclophosphamide and benefits of gonadotropin releasing hormone agonists (GnRHa) in women of child-bearing age with autoimmune rheum	7
Voclosporin: a novel calcineurin inhibitor for the management of lupus nephritis	7
The effect of immunotherapy on cross-reactivity between house dust mite and other allergens in house dust mite -sensitized patients with allergic rhinitis	6
Antibodies against phosphorylcholine and protection against atherosclerosis, cardiovascular disease and chronic inflammation	6
Type I interferon detection in autoimmune diseases: challenges and clinical applications	6
Genetic and epigenetic regulation of natural resistance to HIV-1 infection: new approaches to unveil the HESN secret	6
Thunderstorm asthma: an overview of mechanisms and management strategies	6
Local Bacteriotherapy – a promising preventive tool in recurrent respiratory infections	6
The (apparent) antibody paradox in COVID-19	6
BRAF inhibitors and their immunological effects in malignant melanoma	6
Gut-brain communication in COVID-19: molecular mechanisms, mediators, biomarkers, and therapeutics	6
IgG4-related disease: advances in pathophysiology and treatment	6
Efficacy of dimethyl fumarate treatment for moderate-to-severe plaque psoriasis: presentation extracts from the 29th EADV virtual congress, 29-31 October 2020	6
Fatigue in ANCA-associated vasculitis (AAV) and systemic sclerosis (SSc): similarities with Myalgic encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS). A critical review of the literature	6
Glial fibrillary acidic protein as a biomarker in neuromyelitis optica spectrum disorder: a current review	6
The role of genetics in food allergy	6
Immunological mechanisms underlying sterile inflammation in the pathogenesis of atherosclerosis: potential sites for intervention	6
Immunologic underpinnings and treatment of morphea	6
Current status and prospects for the diagnosis of pemphigus vulgaris	6
What is the ideal duration of maintenance therapy for lupus nephritis?	6
Antiphospholipid syndrome: the need for new international classification criteria	6

Recent insights into the pathogenesis of autoimmune hypophysitis	6
Novel therapeutic approaches for cutaneous T cell lymphomas	6
Biosimilar switching in inflammatory bowel disease: from evidence to clinical practice	6
Cardiac involvement in the adult primary vasculitides	5
S. aureus and IgE-mediated diseases: pilot or copilot? A narrative review	5
House dust mites–driven allergic rhinitis: could its natural history be modified?	5
Utilizing type I interferon expression in the identification of antiphospholipid syndrome subsets	5
Managing puerperium in patients with systemic autoimmune diseases: an update	5
The GLP-1 receptor in airway inflammation in asthma: a promising novel target?	5
Genes vs environment in inflammatory bowel disease: an update	5
Interleukin polymorphisms and protein levels associated with lung cancer susceptibility and phenotypes	5
Chimeric antigen receptor-engineered natural killer cells: a promising cancer immunotherapy	5
Bimekizumab: a dual IL-17A and IL-17F inhibitor for the treatment of psoriasis and psoriatic arthritis	5
‘Real-world’ effectiveness of omalizumab in adults with severe allergic asthma: a meta-analysis	5
Predicting the risk of relapse in polymyalgia rheumatica: novel insights	5
Response to letter to the editor: the clinical utility of diagnostic T cell assays for COVID-19	5
Mast cell activation: beyond histamine and tryptase	5
Systematic review of the antiviral properties of TRIM56: a potential therapeutic intervention for COVID-19	5
Pathological relevance and treatment perspective of JAK targeting in systemic lupus erythematosus	5
Pathway to biomarker discovery in psoriatic arthritis	5
Pathways of atopic disease and neurodevelopmental impairment: assessing the evidence for infant antibiotics	5
Targeting the RANK/RANKL pathway in autoimmune disease and malignancy: future perspectives	5
The role of complement and complement therapeutics in neuromyelitis optica spectrum disorders	5
Treatment strategies, including antibiotics, to target the immune component of rosacea	5
5-Aza-2’-deoxycytidine may enhance the frequency of T regulatory cells from CD4+ naïve T cells isolated from the peripheral blood of patients with chronic HBV infection	5
Immune mechanisms, the role of complement, and related therapies in autoimmune neuropathies	5
Rationale for IL-37 as a novel therapeutic agent in inflammation	5
Perspectives for immunotherapy in noninfectious immune mediated uveitis	5
Nintedanib for the treatment of systemic sclerosis-associated interstitial lung disease	5
Proportion of T follicular helper cells in peripheral blood of rheumatoid arthritis patients: a systematic review and meta-analysis	5
The power of the EUSTAR cohort: key findings to date and implications for management of systemic sclerosis patients	5
The suitability of treating atopic dermatitis with Janus kinase inhibitors	5
TL1A as a therapeutic target in inflammatory bowel disease	5
How effective are JAK-inhibitors? Perspectives from clinical trials and real-world studies	5
Genomic and transcriptional changes in IFNγ pathway genes are putative biomarkers of response to ipilimumab immunotherapy in melanoma patients	5
Emergence of an adaptive immune paradigm to explain celiac disease: a perspective on new evidence and implications for future interventions and diagnosis	5
Lymphocytes subsets in correlation with clinical profile in CVID patients without monogenic defects	5
TYK2 inhibition: changing the treatment landscape for psoriasis?	4
The importance of transition from pediatric to adult rheumatology care in juvenile idiopathic arthritis	4
An updated evaluation of avatrombopag for the treatment of chronic immune thrombocytopenia	4
Sepsis, immunosuppression and the role of epigenetic mechanisms	4
The oft-overlooked cardiovascular complications of inflammatory bowel disease	4
A review of disease burden and clinical management for generalized pustular psoriasis in China	4
Precision medicine in the allergy clinic: the application of component resolved diagnosis	4
Biomarker-driven development of new therapies for autoimmune diseases: current status and future promises	4
Temporal trends in anaphylaxis ED visits over the last decade and the effect of COVID-19 pandemic on these trends	4
Combination immunotherapy for pancreatic cancer: challenges and future considerations	4
Diagnosis and management of systemic sclerosis-related calcinosis	4
Evaluation of different classification criteria in children with Behcet disease: results from a single referral center	4
Enthesitis-related arthritis and spondylarthritis: the same disease or disparate entities?	4
Development and clinical application of bispecific antibody in the treatment of colorectal cancer	4
How suitable are JAK inhibitors in treating the inflammatory component in patients with alopecia areata and vitiligo?	4
Circulating NT-proANP level is a predictor of mortality for systemic sclerosis: a retrospective study of an Italian cohort	4
Vitamin D: does it help Tregs in active rheumatoid arthritis patients	4
Gut microbiome in type 1 diabetes: the immunological perspective	4
Clinical pearls and promising therapies in myositis	4
The future clinical implications of trained immunity	4
Evaluating the role of chemokines and chemokine receptors involved in coronavirus infection	4
A review of berotralstat for the treatment of hereditary angioedema	4
Mucosal and systemic immune responses to Vibrio cholerae infection and oral cholera vaccines (OCVs) in humans: a systematic review	4
The association between IL17, fatigue and quality of life in psoriatic arthritis patients	4
Efficacy and safety of imatinib mesylate in systemic sclerosis. A systematic review and meta-analysis	4
The emerging role of IL-23 in asthma and its clinical implications	4
Inflammatory bowel disease manifestations in spondyloarthritis: considerations for the clinician	4
Peanut (Arachis hypogaea) allergen powder-dnfp for the mitigation of allergic reactions to peanuts in children and adolescents	4
High platelet-lymphocyte ratio is a risk factor for 30-day mortality in in-hospital cardiac arrest patients: a case-control study	4
B cells and upper airway disease: allergic rhinitis and chronic rhinosinusitis with nasal polyps evaluated	4
Evaluation of switching or simultaneous use of biologic treatment in patients with severe chronic rhinosinusitis with nasal polyps and severe asthma. Considerations in clinical decision making	4
Cytokine alterations in psoriasis: an updated review	4
A critical review of halobetasol propionate foam (0.05%) as a treatment option for adolescent plaque psoriasis	3
Therapeutic perspectives on the metabolism of lymphocytes in patients with rheumatoid arthritis and systemic lupus erythematosus	3
Tackling medical misinformation in allergy and immunology practice	3
Pediatric chronic spontaneous urticaria: a brief clinician’s guide	3
Inducibility or predestination? Queries and concepts around drug-free remission in rheumatoid arthritis	3
Vitamin D as disease-modifying therapy for multiple sclerosis?	3
Growth differentiation factor-15 as an emerging biomarker for identifying myositis	3
Reducing lupus flares: should we be more careful about stopping glucocorticoids?	3
Comparing available treatments for pollen-induced allergic rhinitis in children	3
Early diagnosis of systemic sclerosis, where do we stand today?	3
Teprotumumab for the treatment of thyroid eye disease	3
Current evaluation and management of patients with chronic rhinosinusitis and nasal polyps	3
Antiphospholipid antibodies and osteonecrosis in systemic lupus erythematosus: a meta-analysis	3
Predicting lupus low disease activity state and remission in SLE: novel insights	3
The methylenetetrahydrofolate reductase 1298 A>C polymorphism is associated with an increased risk of inflammatory bowel disease: evidence from a meta-analysis	3
Recent advances in potential targets for eosinophilic esophagitis treatments	3
An IPF-like disease course in disorders other than IPF: how can this be anticipated, recognized, and managed?	3
Neurological adverse effects of chimeric antigen receptor T-cell therapy	3
Genomic opportunities for drug repositioning in systemic seropositive rheumatic diseases	3
Update on real-world use of facilitated subcutaneous immunoglobulin and immune globulin subcutaneous (human) 20% solution in patients with immunodeficiencies: poster extracts from the 19th Biennial Me	3
Biomarkers guiding biological therapeutic strategies in chronic rhinosinusitis with nasal polyps: an emerging challenge	3
The Impact of Preeclampsia in Lupus Nephritis	3
Immune dysfunction in inborn errors of immunity causing malignancies	3
The prevalence of thyroid autoantibodies in autoimmune connective tissue diseases: a systematic review and meta-analysis	3
Phosphatidylinositol 3-kinase signaling and immune regulation: insights into disease pathogenesis and clinical implications	3
Probiotics in asthma management: fiction or truth?	3