Molecular Systems Biology

Papers
(The H4-Index of Molecular Systems Biology is 31. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-09-01 to 2025-09-01.)
ArticleCitations
Development and validation of AI/ML derived splice-switching oligonucleotides410
A split intein and split luciferase-coupled system for detecting protein-protein interactions172
Systematic identification of 20S proteasome substrates143
Cell‐to‐cell and type‐to‐type heterogeneity of signaling networks: insights from the crowd109
Stress‐sensitive dynamics of miRNAs and Elba1 in Drosophila embryogenesis94
Exogenous prion-like proteins and their potential to trigger cognitive dysfunction93
State of the interactomes: an evaluation of molecular networks for generating biological insights73
SARS‐CoV‐2–host proteome interactions for antiviral drug discovery71
Dynamic human liver proteome atlas reveals functional insights into disease pathways70
Leveraging prior knowledge to infer gene regulatory networks from single-cell RNA-sequencing data68
Ultra‐high sensitivity mass spectrometry quantifies single‐cell proteome changes upon perturbation65
Author Correction: Systematic protein-protein interaction mapping for clinically relevant human GPCRs63
A transient mutational burst occurs during yeast colony development58
Time‐series transcriptomics and proteomics reveal alternative modes to decode p53 oscillations54
Host inflammatory dynamics reveal placental immune modulation by Group B Streptococcus during pregnancy51
Dimensionality reduction methods for extracting functional networks from large‐scaleCRISPRscreens50
Enhancing nutritional niche and host defenses by modifying the gut microbiome49
A proximity proteomics pipeline with improved reproducibility and throughput45
Predicting cellular responses to complex perturbations in high‐throughput screens45
High‐efficiency delivery of CRISPR‐Cas9 by engineered probiotics enables precise microbiome editing44
Suboptimal resource allocation in changing environments constrains response and growth in bacteria41
The genotype‐phenotype landscape of an allosteric protein40
Detection of PatIent-Level distances from single cell genomics and pathomics data with Optimal Transport (PILOT)39
Machine learning identifies molecular regulators and therapeutics for targeting SARS‐CoV2‐induced cytokine release39
Tensor‐structured decomposition improves systems serology analysis38
Characterizing chemical signaling between engineered “microbial sentinels” in porous microplates37
Author Correction: From coarse to fine: the absolute Escherichia coli proteome under diverse growth conditions35
Comprehensive quantitative modeling of translation efficiency in a genome‐reduced bacterium34
What we can learn from deep space communication for reproducible bioimaging and data analysis34
Systematic identification of structure-specific protein–protein interactions33
Yeast9: a consensus genome-scale metabolic model for S. cerevisiae curated by the community32
Deep learning for protein structure prediction and design—progress and applications31
Metabolic mutations reduce antibiotic susceptibility of E. coli by pathway-specific bottlenecks31
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