OOIR: Observatory of International Research

Papers

(The H4-Index of Molecular Systems Biology is 31. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-10-01 to 2025-10-01.)

Article	Citations
Stress‐sensitive dynamics of miRNAs and Elba1 in Drosophila embryogenesis	420
Exogenous prion-like proteins and their potential to trigger cognitive dysfunction	182
State of the interactomes: an evaluation of molecular networks for generating biological insights	160
Cell‐to‐cell and type‐to‐type heterogeneity of signaling networks: insights from the crowd	113
Systematic identification of 20S proteasome substrates	96
Dynamic human liver proteome atlas reveals functional insights into disease pathways	96
SARS‐CoV‐2–host proteome interactions for antiviral drug discovery	78
Leveraging prior knowledge to infer gene regulatory networks from single-cell RNA-sequencing data	74
Development and validation of AI/ML derived splice-switching oligonucleotides	71
A split intein and split luciferase-coupled system for detecting protein-protein interactions	69
Ultra‐high sensitivity mass spectrometry quantifies single‐cell proteome changes upon perturbation	65
Author Correction: Systematic protein-protein interaction mapping for clinically relevant human GPCRs	64
A transient mutational burst occurs during yeast colony development	56
Suboptimal resource allocation in changing environments constrains response and growth in bacteria	54
A proximity proteomics pipeline with improved reproducibility and throughput	51
Dimensionality reduction methods for extracting functional networks from large‐scaleCRISPRscreens	51
Enhancing nutritional niche and host defenses by modifying the gut microbiome	50
Host inflammatory dynamics reveal placental immune modulation by Group B Streptococcus during pregnancy	45
High‐efficiency delivery of CRISPR‐Cas9 by engineered probiotics enables precise microbiome editing	45
Time‐series transcriptomics and proteomics reveal alternative modes to decode p53 oscillations	43
Predicting cellular responses to complex perturbations in high‐throughput screens	42
Epigenomic landscape of single vascular cells reflects developmental origin and disease risk loci	40
Author Correction: From coarse to fine: the absolute Escherichia coli proteome under diverse growth conditions	40
What we can learn from deep space communication for reproducible bioimaging and data analysis	38
Metabolic mutations reduce antibiotic susceptibility of E. coli by pathway-specific bottlenecks	37

Characterizing chemical signaling between engineered “microbial sentinels” in porous microplates	37
Deep learning for protein structure prediction and design—progress and applications	36
Systematic identification of structure-specific protein–protein interactions	35
Comprehensive quantitative modeling of translation efficiency in a genome‐reduced bacterium	34
The genotype‐phenotype landscape of an allosteric protein	32
Yeast9: a consensus genome-scale metabolic model for S. cerevisiae curated by the community	32
Detection of PatIent-Level distances from single cell genomics and pathomics data with Optimal Transport (PILOT)	31