OOIR: Observatory of International Research

Papers

(The H4-Index of Molecular Systems Biology is 35. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-05-01 to 2025-05-01.)

Article	Citations
Stress‐sensitive dynamics of miRNAs and Elba1 in Drosophila embryogenesis	379
Leveraging prior knowledge to infer gene regulatory networks from single-cell RNA-sequencing data	206
Cell‐to‐cell and type‐to‐type heterogeneity of signaling networks: insights from the crowd	150
A split intein and split luciferase-coupled system for detecting protein-protein interactions	116
Systematic identification of 20S proteasome substrates	116
Dynamic human liver proteome atlas reveals functional insights into disease pathways	113
State of the interactomes: an evaluation of molecular networks for generating biological insights	100
SARS‐CoV‐2–host proteome interactions for antiviral drug discovery	95
Development and validation of AI/ML derived splice-switching oligonucleotides	83
Ultra‐high sensitivity mass spectrometry quantifies single‐cell proteome changes upon perturbation	80
Host inflammatory dynamics reveal placental immune modulation by Group B Streptococcus during pregnancy	77
Author Correction: Systematic protein-protein interaction mapping for clinically relevant human GPCRs	73
Enhancing nutritional niche and host defenses by modifying the gut microbiome	65
Adaptive laboratory evolution of microbial co‐cultures for improved metabolite secretion	64
Suboptimal resource allocation in changing environments constrains response and growth in bacteria	64
Dimensionality reduction methods for extracting functional networks from large‐scaleCRISPRscreens	62
A proximity proteomics pipeline with improved reproducibility and throughput	61
Evaluating the Arrhenius equation for developmental processes	57
High‐efficiency delivery of CRISPR‐Cas9 by engineered probiotics enables precise microbiome editing	56
Predicting cellular responses to complex perturbations in high‐throughput screens	55
Time‐series transcriptomics and proteomics reveal alternative modes to decode p53 oscillations	53
Yeast9: a consensus genome-scale metabolic model for S. cerevisiae curated by the community	52
Deep learning for protein structure prediction and design—progress and applications	48
The genotype‐phenotype landscape of an allosteric protein	47
Machine learning identifies molecular regulators and therapeutics for targeting SARS‐CoV2‐induced cytokine release	47

Systematic identification of structure-specific protein–protein interactions	46
Detection of PatIent-Level distances from single cell genomics and pathomics data with Optimal Transport (PILOT)	43
Quantifying persistence in the T‐cell signaling network using an optically controllable antigen receptor	40
Author Correction: From coarse to fine: the absolute Escherichia coli proteome under diverse growth conditions	39
What we can learn from deep space communication for reproducible bioimaging and data analysis	37
Characterizing chemical signaling between engineered “microbial sentinels” in porous microplates	35
Metabolic mutations reduce antibiotic susceptibility of E. coli by pathway-specific bottlenecks	35
Comprehensive quantitative modeling of translation efficiency in a genome‐reduced bacterium	35
Tensor‐structured decomposition improves systems serology analysis	35
Author Correction: Predictive evolution of metabolic phenotypes using model-designed environments	35