OOIR: Observatory of International Research

Papers

(The H4-Index of Molecular Systems Biology is 31. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-08-01 to 2026-08-01.)

Article	Citations
Exogenous prion-like proteins and their potential to trigger cognitive dysfunction	282
Development and validation of AI/ML derived splice-switching oligonucleotides	275
Cross-species insights from ART-D to uncover evolutionarily conserved oncogenic mechanisms	142
Stress‐sensitive dynamics of miRNAs and Elba1 in Drosophila embryogenesis	111
To cleave or not to cleave: a systemic evaluation of DSS versus DSSO for cross-linking mass spectrometry analysis	93
Dissecting and steering cell dynamics using spatially-informed RNA velocity with veloAgent	89
Leveraging prior knowledge to infer gene regulatory networks from single-cell RNA-sequencing data	82
A split intein and split luciferase-coupled system for detecting protein-protein interactions	69
Systematic identification of 20S proteasome substrates	66
Methylation reprogramming associated with aggressive prostate cancer and ancestral disparities	66
State of the interactomes: an evaluation of molecular networks for generating biological insights	62
Toward trustworthy healthcare AI: designing academic research for translation readiness	61
Enhancing nutritional niche and host defenses by modifying the gut microbiome	60
Host inflammatory dynamics reveal placental immune modulation by Group B Streptococcus during pregnancy	58
Molecular Systems Biology at 20: reflecting on the past, envisioning the future	58
Author Correction: Spatial proteomics of ovarian cancer precursors delineates early disease changes and drug targets	57
Unlocking CRISPR-Cas9 editing for widely diverse Dictyostelid species	49
Chromosome length is constrained by spindle scaling to ensure faithful mitosis in mammals	49
Author Correction: Systematic protein-protein interaction mapping for clinically relevant human GPCRs	44
A transient mutational burst occurs during yeast colony development	43
Dimensionality reduction methods for extracting functional networks from large‐scale CRISPR screens	41
A proximity proteomics pipeline with improved reproducibility and throughput	39
Progress and new challenges in image-based profiling	38
Predicting cellular responses to complex perturbations in high‐throughput screens	37
Author Correction: From coarse to fine: the absolute Escherichia coli proteome under diverse growth conditions	36

Epigenomic landscape of single vascular cells reflects developmental origin and disease risk loci	36
Metabolic mutations reduce antibiotic susceptibility of E. coli by pathway-specific bottlenecks	36
Systematic identification of structure-specific protein–protein interactions	36
What we can learn from deep space communication for reproducible bioimaging and data analysis	35
Comprehensive quantitative modeling of translation efficiency in a genome‐reduced bacterium	34
A novel combination therapy for ER+ breast cancer suppresses drug resistance via an evolutionary double-bind	33
Yeast9: a consensus genome-scale metabolic model for S. cerevisiae curated by the community	31