OOIR: Observatory of International Research

Papers

(The H4-Index of Molecular Systems Biology is 31. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-06-01 to 2026-06-01.)

Article	Citations
Exogenous prion-like proteins and their potential to trigger cognitive dysfunction	265
State of the interactomes: an evaluation of molecular networks for generating biological insights	245
Methylation reprogramming associated with aggressive prostate cancer and ancestral disparities	139
Development and validation of AI/ML derived splice-switching oligonucleotides	104
Cross-species insights from ART-D to uncover evolutionarily conserved oncogenic mechanisms	87
Dissecting and steering cell dynamics using spatially-informed RNA velocity with veloAgent	80
A split intein and split luciferase-coupled system for detecting protein-protein interactions	79
Stress‐sensitive dynamics of miRNAs and Elba1 in Drosophila embryogenesis	67
Leveraging prior knowledge to infer gene regulatory networks from single-cell RNA-sequencing data	64
Systematic identification of 20S proteasome substrates	60
Toward trustworthy healthcare AI: designing academic research for translation readiness	58
Enhancing nutritional niche and host defenses by modifying the gut microbiome	57
Dimensionality reduction methods for extracting functional networks from large‐scale CRISPR screens	55
Host inflammatory dynamics reveal placental immune modulation by Group B Streptococcus during pregnancy	53
Progress and new challenges in image-based profiling	53
Molecular Systems Biology at 20: reflecting on the past, envisioning the future	50
Author Correction: Spatial proteomics of ovarian cancer precursors delineates early disease changes and drug targets	48
Unlocking CRISPR-Cas9 editing for widely diverse Dictyostelid species	48
Chromosome length is constrained by spindle scaling to ensure faithful mitosis in mammals	45
Author Correction: Systematic protein-protein interaction mapping for clinically relevant human GPCRs	44
A transient mutational burst occurs during yeast colony development	42
A proximity proteomics pipeline with improved reproducibility and throughput	39
Deep learning for protein structure prediction and design—progress and applications	37
Predicting cellular responses to complex perturbations in high‐throughput screens	37
Epigenomic landscape of single vascular cells reflects developmental origin and disease risk loci	37

Author Correction: From coarse to fine: the absolute Escherichia coli proteome under diverse growth conditions	35
What we can learn from deep space communication for reproducible bioimaging and data analysis	35
Comprehensive quantitative modeling of translation efficiency in a genome‐reduced bacterium	34
A novel combination therapy for ER+ breast cancer suppresses drug resistance via an evolutionary double-bind	34
Detection of PatIent-Level distances from single cell genomics and pathomics data with Optimal Transport (PILOT)	34
Metabolic mutations reduce antibiotic susceptibility of E. coli by pathway-specific bottlenecks	34