OOIR: Observatory of International Research

Papers

(The median citation count of Particle and Fibre Toxicology is 8. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-11-01 to 2024-11-01.)

Article	Citations
Immunotoxicity and intestinal effects of nano- and microplastics: a review of the literature	355
Underestimated health risks: polystyrene micro- and nanoplastics jointly induce intestinal barrier dysfunction by ROS-mediated epithelial cell apoptosis	235
Cardiovascular health impacts of wildfire smoke exposure	125
Chronic exposure to polystyrene microplastics induced male reproductive toxicity and decreased testosterone levels via the LH-mediated LHR/cAMP/PKA/StAR pathway	122
The critical role of endothelial function in fine particulate matter-induced atherosclerosis	86
Translocation of (ultra)fine particles and nanoparticles across the placenta; a systematic review on the evidence of in vitro, ex vivo, and in vivo studies	77
Consequences of nano and microplastic exposure in rodent models: the known and unknown	71
The mechanism of cell death induced by silver nanoparticles is distinct from silver cations	68
Coronas of micro/nano plastics: a key determinant in their risk assessments	67
A comprehensive understanding of ambient particulate matter and its components on the adverse health effects based from epidemiological and laboratory evidence	62
Ultrasmall iron oxide nanoparticles cause significant toxicity by specifically inducing acute oxidative stress to multiple organs	59
Airborne particulate matter (PM2.5) triggers ocular hypertension and glaucoma through pyroptosis	59
Polypropylene nanoplastic exposure leads to lung inflammation through p38-mediated NF-κB pathway due to mitochondrial damage	57
Prospects on the nano-plastic particles internalization and induction of cellular response in human keratinocytes	49
Skin damage induced by zinc oxide nanoparticles combined with UVB is mediated by activating cell pyroptosis via the NLRP3 inflammasome–autophagy–exosomal pathway	49
Size and surface modification of silica nanoparticles affect the severity of lung toxicity by modulating endosomal ROS generation in macrophages	48
In vitro-in vivo correlations of pulmonary inflammogenicity and genotoxicity of MWCNT	41
Copper oxide nanoparticles trigger macrophage cell death with misfolding of Cu/Zn superoxide dismutase 1 (SOD1)	41
Exposure to diesel exhaust particles results in altered lung microbial profiles, associated with increased reactive oxygen species/reactive nitrogen species and inflammation, in C57Bl/6 wildtype mice	40
Physicochemical characterization and genotoxicity of the broad class of carbon nanotubes and nanofibers used or produced in U.S. facilities	38
Nitrogen-doped graphene quantum dots induce ferroptosis through disrupting calcium homeostasis in microglia	32
Short- and long-term polystyrene nano- and microplastic exposure promotes oxidative stress and divergently affects skin cell architecture and Wnt/beta-catenin signaling	31
Retained particle surface area dose drives inflammation in rat lungs following acute, subacute, and subchronic inhalation of nanomaterials	30
Upregulation of ACE2 and TMPRSS2 by particulate matter and idiopathic pulmonary fibrosis: a potential role in severe COVID-19	30
Development of a multi-route physiologically based pharmacokinetic (PBPK) model for nanomaterials: a comparison between a traditional versus a new route-specific approach using gold nanoparticles in r	29

Repeated oral administration of low doses of silver in mice: tissue distribution and effects on central nervous system	29
Controlled human exposure to diesel exhaust: results illuminate health effects of traffic-related air pollution and inform future directions	28
Low levels of fine particulate matter increase vascular damage and reduce pulmonary function in young healthy adults	27
Effects of metal nanoparticles on tight junction-associated proteins via HIF-1α/miR-29b/MMPs pathway in human epidermal keratinocytes	26
Omega-3 fatty acids attenuate cardiovascular effects of short-term exposure to ambient air pollution	25
Single inhalation exposure to polyamide micro and nanoplastic particles impairs vascular dilation without generating pulmonary inflammation in virgin female Sprague Dawley rats	25
The combined effect of food additive titanium dioxide and lipopolysaccharide on mouse intestinal barrier function after chronic exposure of titanium dioxide-contained feedstuffs	24
Titanium dioxide particles from the diet: involvement in the genesis of inflammatory bowel diseases and colorectal cancer	24
Chemistry, lung toxicity and mutagenicity of burn pit smoke-related particulate matter	24
Amine-modified nanoplastics promote the procoagulant activation of isolated human red blood cells and thrombus formation in rats	24
Chronic exposure to PM2.5 aggravates SLE manifestations in lupus-prone mice	23
Polystyrene nanoplastic exposure induces excessive mitophagy by activating AMPK/ULK1 pathway in differentiated SH-SY5Y cells and dopaminergic neurons in vivo	23
Titanium dioxide nanoparticles enhance thrombosis through triggering the phosphatidylserine exposure and procoagulant activation of red blood cells	23
Combined exposure to fine particulate matter and high glucose aggravates endothelial damage by increasing inflammation and mitophagy: the involvement of vitamin D	23
Lung retention and particokinetics of silver and gold nanoparticles in rats following subacute inhalation co-exposure	22
Putative adverse outcome pathways for silver nanoparticle toxicity on mammalian male reproductive system: a literature review	21
Two-year intermittent exposure of a multiwalled carbon nanotube by intratracheal instillation induces lung tumors and pleural mesotheliomas in F344 rats	21
Exposure to environmentally relevant concentrations of ambient fine particulate matter (PM2.5) depletes the ovarian follicle reserve and causes sex-dependent cardiovascular changes in apolipoprotein E	21
Neuropathology changed by 3- and 6-months low-level PM2.5 inhalation exposure in spontaneously hypertensive rats	20
Silica-coated magnetic nanoparticles activate microglia and induce neurotoxic d-serine secretion	20
Long-term exposure to polystyrene microplastics triggers premature testicular aging	20
Nanomaterial- and shape-dependency of TLR2 and TLR4 mediated signaling following pulmonary exposure to carbonaceous nanomaterials in mice	20
Oxidative stress generated by polycyclic aromatic hydrocarbons from ambient particulate matter enhance vascular smooth muscle cell migration through MMP upregulation and actin reorganization	19
Diesel exhaust particles alter the profile and function of the gut microbiota upon subchronic oral administration in mice	19
Biotransformation of rare earth oxide nanoparticles eliciting microbiota imbalance	19
Differential effects of intense exercise and pollution on the airways in a murine model	19
The potential involvement of inhaled iron (Fe) in the neurotoxic effects of ultrafine particulate matter air pollution exposure on brain development in mice	18
Digital research data: from analysis of existing standards to a scientific foundation for a modular metadata schema in nanosafety	18
Changes of physico-chemical properties of nano-biomaterials by digestion fluids affect the physiological properties of epithelial intestinal cells and barrier models	18
Pulmonary dust foci as rat pneumoconiosis lesion induced by titanium dioxide nanoparticles in 13-week inhalation study	18
Gut microbiome and plasma metabolome changes in rats after oral gavage of nanoparticles: sensitive indicators of possible adverse health effects	18
Use of an in silico knowledge discovery approach to determine mechanistic studies of silver nanoparticles-induced toxicity from in vitro to in vivo	17
The pulmonary toxicity of carboxylated or aminated multi-walled carbon nanotubes in mice is determined by the prior purification method	17
The pro-inflammatory effects of combined exposure to diesel exhaust particles and mineral particles in human bronchial epithelial cells	17
Respirable stone particles differ in their ability to induce cytotoxicity and pro-inflammatory responses in cell models of the human airways	17
Dimethylarginine dimethylaminohydrolase 1 protects PM2.5 exposure-induced lung injury in mice by repressing inflammation and oxidative stress	16
Lung recovery from DNA damage induced by graphene oxide is dependent on size, dose and inflammation profile	16
Coal dust exposure triggers heterogeneity of transcriptional profiles in mouse pneumoconiosis and Vitamin D remedies	16
Acute phase response following pulmonary exposure to soluble and insoluble metal oxide nanomaterials in mice	15
Compositional and structural analysis of engineered stones and inorganic particles in silicotic nodules of exposed workers	15
Cobalt oxide nanoparticles induce oxidative stress and alter electromechanical function in rat ventricular myocytes	15
Time course of pulmonary inflammation and trace element biodistribution during and after sub-acute inhalation exposure to copper oxide nanoparticles in a murine model	15
Lung-gut axis of microbiome alterations following co-exposure to ultrafine carbon black and ozone	15
Surface functionalization and size modulate the formation of reactive oxygen species and genotoxic effects of cellulose nanofibrils	15
Aryl hydrocarbon receptor activation-mediated vascular toxicity of ambient fine particulate matter: contribution of polycyclic aromatic hydrocarbons and osteopontin as a biomarker	15
Airborne particulate matters induce thrombopoiesis from megakaryocytes through regulating mitochondrial oxidative phosphorylation	14
Titanium dioxide nanoparticles impair the inner blood-retinal barrier and retinal electrophysiology through rapid ADAM17 activation and claudin-5 degradation	14
Assessment of the toxicity and carcinogenicity of double-walled carbon nanotubes in the rat lung after intratracheal instillation: a two-year study	14
Landscape of lipidomic metabolites in gut-liver axis of Sprague–Dawley rats after oral exposure to titanium dioxide nanoparticles	14
Inflammogenic effect of polyacrylic acid in rat lung following intratracheal instillation	14

Acute cardiovascular effects of controlled exposure to dilute Petrodiesel and biodiesel exhaust in healthy volunteers: a crossover study	13
Prolonged exposure to traffic-related particulate matter and gaseous pollutants implicate distinct molecular mechanisms of lung injury in rats	13
Chronic exposure to diesel exhaust may cause small airway wall thickening without lumen narrowing: a quantitative computerized tomography study in Chinese diesel engine testers	13
Single-cell transcriptomics reveals immune dysregulation mediated by IL-17A in initiation of chronic lung injuries upon real-ambient particulate matter exposure	13
Surface charge-dependent mitochondrial response to similar intracellular nanoparticle contents at sublethal dosages	12
Pro-thrombotic changes associated with exposure to ambient ultrafine particles in patients with chronic obstructive pulmonary disease: roles of lipid peroxidation and systemic inflammation	12
Silica-coated magnetic-nanoparticle-induced cytotoxicity is reduced in microglia by glutathione and citrate identified using integrated omics	11
Dose–response relationship of pulmonary disorders by inhalation exposure to cross-linked water-soluble acrylic acid polymers in F344 rats	11
Exposure to high dose of polystyrene nanoplastics causes trophoblast cell apoptosis and induces miscarriage	11
Silica encapsulation of ZnO nanoparticles reduces their toxicity for cumulus cell-oocyte-complex expansion	11
The in vitro gastrointestinal digestion-associated protein corona of polystyrene nano- and microplastics increases their uptake by human THP-1-derived macrophages	11
Respiratory and systemic impacts following MWCNT inhalation in B6C3F1/N mice	10
Aluminium oxide nanoparticles compromise spatial memory performance and proBDNF-mediated neuronal function in the hippocampus of rats	10
Multi-dimensional evaluation of cardiotoxicity in mice following respiratory exposure to polystyrene nanoplastics	10
Malondialdehyde and anion patterns in exhaled breath condensate among subway workers	10
Transcriptomics of single dose and repeated carbon black and ozone inhalation co-exposure highlight progressive pulmonary mitochondrial dysfunction	10
Impact of in vitro digested zinc oxide nanoparticles on intestinal model systems	10
Macrophage autophagy protects mice from cerium oxide nanoparticle-induced lung fibrosis	10
Nano-titanium dioxide inhalation exposure during gestation drives redox dysregulation and vascular dysfunction across generations	9
Prenatal PM2.5 exposure impairs spatial learning and memory in male mice offspring: from transcriptional regulation to neuronal morphogenesis	9
Label-free detection and quantification of ultrafine particulate matter in lung and heart of mouse and evaluation of tissue injury	9
Exposure to combustion derived particulate matter exacerbates influenza infection in neonatal mice by inhibiting IL22 production	9
Polycyclic aromatic hydrocarbons in urban particle matter exacerbate movement disorder after ischemic stroke via potentiation of neuroinflammation	9
Enhanced silver nanoparticle-induced pulmonary inflammation in a metabolic syndrome mouse model and resolvin D1 treatment	9
Grouping MWCNTs based on their similar potential to cause pulmonary hazard after inhalation: a case-study	9
Attenuation of PM2.5-induced alveolar epithelial cells and lung injury through regulation of mitochondrial fission and fusion	9
Safe by design (SbD) and nanotechnology: a much-discussed topic with a prudence?	9
Inhaled diesel exhaust particles result in microbiome-related systemic inflammation and altered cardiovascular disease biomarkers in C57Bl/6 male mice	9
Polystyrene nanobeads exacerbate chronic colitis in mice involving in oxidative stress and hepatic lipid metabolism	8
Circulatory metabolites trigger ex vivo arterial endothelial cell dysfunction in population chronically exposed to diesel exhaust	8
White matter pathology in alzheimer’s transgenic mice with chronic exposure to low-level ambient fine particulate matter	8
Histopathology of the broad class of carbon nanotubes and nanofibers used or produced in U.S. facilities in a murine model	8
Exposure to silicates and systemic autoimmune-related outcomes in rodents: a systematic review	8
Road tunnel-derived coarse, fine and ultrafine particulate matter: physical and chemical characterization and pro-inflammatory responses in human bronchial epithelial cells	8
A systematic quality evaluation and review of nanomaterial genotoxicity studies: a regulatory perspective	8