OOIR: Observatory of International Research

Papers

(The median citation count of Particle and Fibre Toxicology is 6. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-02-01 to 2025-02-01.)

Article	Citations
Chronic effects of two rutile TiO2 nanomaterials in human intestinal and hepatic cell lines	241
Silica encapsulation of ZnO nanoparticles reduces their toxicity for cumulus cell-oocyte-complex expansion	129
Rounded atelectasis after exposure to refractory ceramic fibres (RCF)	81
Femtosecond pulsed laser microscopy: a new tool to assess the in vitro delivered dose of carbon nanotubes in cell culture experiments	71
Worse pulmonary function in association with cumulative exposure to nanomaterials. Hints of a mediation effect via pulmonary inflammation	67
Chronic exposure to diesel exhaust may cause small airway wall thickening without lumen narrowing: a quantitative computerized tomography study in Chinese diesel engine testers	64
Histopathology of the broad class of carbon nanotubes and nanofibers used or produced in U.S. facilities in a murine model	62
Lung function and self-rated symptoms in healthy volunteers after exposure to hydrotreated vegetable oil (HVO) exhaust with and without particles	62
Macrophage-mediated tissue response evoked by subchronic inhalation of lead oxide nanoparticles is associated with the alteration of phospholipases C and cholesterol transporters	59
Addressing the relevance of polystyrene nano- and microplastic particles used to support exposure, toxicity and risk assessment: implications and recommendations	49
Human exposure to diesel exhaust induces CYP1A1 expression and AhR activation without a coordinated antioxidant response	49
Controlled human exposures: a review and comparison of the health effects of diesel exhaust and wood smoke	48
Toxicological inhalation studies in rats to substantiate grouping of zinc oxide nanoforms	41
Concentration-dependent increase in symptoms due to diesel exhaust in a controlled human exposure study	41
Coal dust exposure triggers heterogeneity of transcriptional profiles in mouse pneumoconiosis and Vitamin D remedies	32
Underestimated health risks: polystyrene micro- and nanoplastics jointly induce intestinal barrier dysfunction by ROS-mediated epithelial cell apoptosis	31
Zinc oxide nanoparticles exacerbate skin epithelial cell damage by upregulating pro-inflammatory cytokines and exosome secretion in M1 macrophages following UVB irradiation-induced skin injury	30
MMP-3-mediated cleavage of OPN is involved in copper oxide nanoparticle-induced activation of fibroblasts	30
Long-term PM2.5 exposure disrupts corneal epithelial homeostasis by impairing limbal stem/progenitor cells in humans and rat models	30
Cytotoxicity analysis of biomass combustion particles in human pulmonary alveolar epithelial cells on an air–liquid interface/dynamic culture platform	29
Single-cell transcriptome sequencing–based analysis: probing the mechanisms of glycoprotein NMB regulation of epithelial cells involved in silicosis	29
Exposure to environmentally relevant concentrations of ambient fine particulate matter (PM2.5) depletes the ovarian follicle reserve and causes sex-dependent cardiovascular changes in apolipoprotein E	28
Aryl hydrocarbon receptor activation-mediated vascular toxicity of ambient fine particulate matter: contribution of polycyclic aromatic hydrocarbons and osteopontin as a biomarker	26
Polypropylene nanoplastic exposure leads to lung inflammation through p38-mediated NF-κB pathway due to mitochondrial damage	26
Inhaled diesel exhaust particles result in microbiome-related systemic inflammation and altered cardiovascular disease biomarkers in C57Bl/6 male mice	25

Diesel exhaust particles alter the profile and function of the gut microbiota upon subchronic oral administration in mice	25
Oral intake of titanium dioxide nanoparticles affect the course and prognosis of ulcerative colitis in mice: involvement of the ROS-TXNIP-NLRP3 inflammasome pathway	24
Surface charge-dependent mitochondrial response to similar intracellular nanoparticle contents at sublethal dosages	24
Exposure to combustion derived particulate matter exacerbates influenza infection in neonatal mice by inhibiting IL22 production	24
Impact of in vitro digested zinc oxide nanoparticles on intestinal model systems	24
Circulatory metabolites trigger ex vivo arterial endothelial cell dysfunction in population chronically exposed to diesel exhaust	24
Differential effects of intense exercise and pollution on the airways in a murine model	24
Acute exposure to polystyrene nanoparticles promotes liver injury by inducing mitochondrial ROS-dependent necroptosis and augmenting macrophage-hepatocyte crosstalk	23
Development of a multi-route physiologically based pharmacokinetic (PBPK) model for nanomaterials: a comparison between a traditional versus a new route-specific approach using gold nanoparticles in r	23
Multi-dimensional evaluation of cardiotoxicity in mice following respiratory exposure to polystyrene nanoplastics	21
Dose–response relationship of pulmonary disorders by inhalation exposure to cross-linked water-soluble acrylic acid polymers in F344 rats	20
A systematic quality evaluation and review of nanomaterial genotoxicity studies: a regulatory perspective	20
Deciphering key nano-bio interface descriptors to predict nanoparticle-induced lung fibrosis	20
Landscape of lipidomic metabolites in gut-liver axis of Sprague–Dawley rats after oral exposure to titanium dioxide nanoparticles	19
Reduced bronchoalveolar macrophage phagocytosis and cytotoxic effects after controlled short-term exposure to wood smoke in healthy humans	19
In vitro inflammation and toxicity assessment of pre- and post-incinerated organomodified nanoclays to macrophages using high-throughput screening approaches	19
Biotransformation of rare earth oxide nanoparticles eliciting microbiota imbalance	19
Acute and continuous exposure of airborne fine particulate matter (PM2.5): diverse outer blood–retinal barrier damages and disease susceptibilities	18
A novel in-situ method to determine the respiratory tract deposition of carbonaceous particles reveals dangers of public commuting in highly polluted megacity	18
Repeated oral administration of low doses of silver in mice: tissue distribution and effects on central nervous system	18
Toxicokinetic study following intratracheal instillation or oral gavage of two [7Be]-tagged carbon black samples	18
Pulmonary delivery of the broad-spectrum matrix metalloproteinase inhibitor marimastat diminishes multiwalled carbon nanotube-induced circulating bioactivity without reducing pulmonary inflammation	18
Placental-fetal distribution of carbon particles in a pregnant rabbit model after repeated exposure to diluted diesel engine exhaust	17
Ferroptosis contributing to cardiomyocyte injury induced by silica nanoparticles via miR-125b-2-3p/HO-1 signaling	17
Epithelial MAPK signaling directs endothelial NRF2 signaling and IL-8 secretion in a tri-culture model of the alveolar-microvascular interface following diesel exhaust particulate (DEP) exposure	17
Long-term exposure to polystyrene microplastics triggers premature testicular aging	16
Micro- and nanoplastics concepts for particle and fibre toxicologists	16
An experimental study on lung deposition of inhaled 2 μm particles in relation to lung characteristics and deposition models	16
Amine-modified nanoplastics promote the procoagulant activation of isolated human red blood cells and thrombus formation in rats	16
The discovery of regional neurotoxicity-associated metabolic alterations induced by carbon quantum dots in brain of mice using a spatial metabolomics analysis	15
Pro-thrombotic changes associated with exposure to ambient ultrafine particles in patients with chronic obstructive pulmonary disease: roles of lipid peroxidation and systemic inflammation	15
The potential involvement of inhaled iron (Fe) in the neurotoxic effects of ultrafine particulate matter air pollution exposure on brain development in mice	15
Controlled human exposure to diesel exhaust: results illuminate health effects of traffic-related air pollution and inform future directions	15
Titanium dioxide and carbon black nanoparticles disrupt neuronal homeostasis via excessive activation of cellular prion protein signaling	15
Two-year intermittent exposure of a multiwalled carbon nanotube by intratracheal instillation induces lung tumors and pleural mesotheliomas in F344 rats	15
Road tunnel-derived coarse, fine and ultrafine particulate matter: physical and chemical characterization and pro-inflammatory responses in human bronchial epithelial cells	14
Sex affects the response of Wistar rats to polyvinyl pyrrolidone (PVP)-coated silver nanoparticles in an oral 28 days repeated dose toxicity study	14
Macrophage autophagy protects mice from cerium oxide nanoparticle-induced lung fibrosis	14
Grouping MWCNTs based on their similar potential to cause pulmonary hazard after inhalation: a case-study	13
White matter pathology in alzheimer’s transgenic mice with chronic exposure to low-level ambient fine particulate matter	13
Hazard assessment of nanomaterials: how to meet the requirements for (next generation) risk assessment	13
Type 1 diabetes and diet-induced obesity predispose C57BL/6J mice to PM2.5-induced lung injury: a comparative study	13
Time course of pulmonary inflammation and trace element biodistribution during and after sub-acute inhalation exposure to copper oxide nanoparticles in a murine model	12
Towards a risk assessment framework for micro- and nanoplastic particles for human health	12
The chemical composition of secondary organic aerosols regulates transcriptomic and metabolomic signaling in an epithelial-endothelial in vitro coculture	12
Correction: Perinatal foodborne titanium dioxide exposure-mediated dysbiosis predisposes mice to develop colitis through life	11
Coronas of micro/nano plastics: a key determinant in their risk assessments	11
Gut microbiome and plasma metabolome changes in rats after oral gavage of nanoparticles: sensitive indicators of possible adverse health effects	11
Changes of physico-chemical properties of nano-biomaterials by digestion fluids affect the physiological properties of epithelial intestinal cells and barrier models	11
Malignant peritoneal mesotheliomas of rats induced by multiwalled carbon nanotubes and amosite asbestos: transcriptome and epigenetic profiles	11

Malondialdehyde and anion patterns in exhaled breath condensate among subway workers	11
Particulate matter from car exhaust alters function of human iPSC-derived microglia	10
Enhanced silver nanoparticle-induced pulmonary inflammation in a metabolic syndrome mouse model and resolvin D1 treatment	10
Biokinetics of subacutely co-inhaled same size gold and silver nanoparticles	10
Decidual derived exosomal miR-99a-5p targets Ppp2r5a to inhibit trophoblast invasion in response to CeO2NPs exposure	10
Human dendritic cell maturation induced by amorphous silica nanoparticles is Syk-dependent and triggered by lipid raft aggregation	10
Skin damage induced by zinc oxide nanoparticles combined with UVB is mediated by activating cell pyroptosis via the NLRP3 inflammasome–autophagy–exosomal pathway	10
Effect of sp3/sp2 carbon ratio and hydrodynamic size on the biodistribution kinetics of nanodiamonds in mice via intravenous injection	10
A novel insight into mechanism of derangement of coagulation balance: interactions of quantum dots with coagulation-related proteins	10
Murine in utero exposure to simulated complex urban air pollution disturbs offspring gut maturation and microbiota during intestinal suckling-to-weaning transition in a sex-dependent manner	10
Acute cardiovascular effects of controlled exposure to dilute Petrodiesel and biodiesel exhaust in healthy volunteers: a crossover study	9
Derivation of first-order dissolution rates to estimate particle clearance and burden in the human respiratory tract	9
Polystyrene nanobeads exacerbate chronic colitis in mice involving in oxidative stress and hepatic lipid metabolism	9
Inflammogenic effect of polyacrylic acid in rat lung following intratracheal instillation	9
Systemic immunological responses are dependent on sex and ovarian hormone presence following acute inhaled woodsmoke exposure	9
Single-cell transcriptomics reveals immune dysregulation mediated by IL-17A in initiation of chronic lung injuries upon real-ambient particulate matter exposure	9
Respirable stone particles differ in their ability to induce cytotoxicity and pro-inflammatory responses in cell models of the human airways	8
Investigation of pulmonary inflammatory responses following intratracheal instillation of and inhalation exposure to polypropylene microplastics	8
Titanium dioxide particles from the diet: involvement in the genesis of inflammatory bowel diseases and colorectal cancer	8
Respiratory and systemic impacts following MWCNT inhalation in B6C3F1/N mice	8
Maternal exposure to ultrafine particles enhances influenza infection during pregnancy	8
Uncovering the Fate and Risks of Intravenously Injected Prussian Blue Nanoparticles in mice by an Integrated Methodology of Toxicology, Pharmacokinetics, Proteomics, and Metabolomics	8
Multimodal pulmonary clearance kinetics of carbon black nanoparticles deposited in the lungs of rats: the role of alveolar macrophages	8
Lung versus gut exposure to air pollution particles differentially affect metabolic health in mice	7
Transcriptomics of single dose and repeated carbon black and ozone inhalation co-exposure highlight progressive pulmonary mitochondrial dysfunction	7
Lung recovery from DNA damage induced by graphene oxide is dependent on size, dose and inflammation profile	7
Impact on murine neurodevelopment of early-life exposure to airborne ultrafine carbon nanoparticles	7
Pulmonary dust foci as rat pneumoconiosis lesion induced by titanium dioxide nanoparticles in 13-week inhalation study	7
Cell-nanoparticle stickiness and dose delivery in a multi-model in silico platform: DosiGUI	7
Cellular response of keratinocytes to the entry and accumulation of nanoplastic particles	7
Prenatal PM2.5 exposure impairs spatial learning and memory in male mice offspring: from transcriptional regulation to neuronal morphogenesis	7
Current understanding of the impact of United States military airborne hazards and burn pit exposures on respiratory health	7
Polystyrene nanoplastics with different functional groups and charges have different impacts on type 2 diabetes	6
Safe by design (SbD) and nanotechnology: a much-discussed topic with a prudence?	6
Acute phase response following pulmonary exposure to soluble and insoluble metal oxide nanomaterials in mice	6
Compositional and structural analysis of engineered stones and inorganic particles in silicotic nodules of exposed workers	6
ROS/mtROS promotes TNTs formation via the PI3K/AKT/mTOR pathway to protect against mitochondrial damages in glial cells induced by engineered nanomaterials	6
Label-free detection and quantification of ultrafine particulate matter in lung and heart of mouse and evaluation of tissue injury	6
Genome-wide DNA methylation sequencing reveals the involvement of ferroptosis in hepatotoxicity induced by dietary exposure to food-grade titanium dioxide	6
High glucose enhances the activation of NLRP3 inflammasome by ambient fine particulate matter in alveolar macrophages	6