Nutrition & Metabolism

Article	Citations
Milk consumption and multiple health outcomes: umbrella review of systematic reviews and meta-analyses in humans	105
Browning of the white adipose tissue regulation: new insights into nutritional and metabolic relevance in health and diseases	83
Time-restricted feeding improves blood glucose and insulin sensitivity in overweight patients with type 2 diabetes: a randomised controlled trial	70
The potential mechanisms of lactate in mediating exercise-enhanced cognitive function: a dual role as an energy supply substrate and a signaling molecule	50
Novel and traditional anthropometric indices for identifying metabolic syndrome in non-overweight/obese adults	44
STAT3 phosphorylation in central leptin resistance	44
Metabolomic signatures for liver tissue and cecum contents in high-fat diet-induced obese mice based on UHPLC-Q-TOF/MS	34
A comprehensive review of long non-coding RNAs in the pathogenesis and development of non-alcoholic fatty liver disease	33
Fat-soluble vitamins: updated review of their role and orchestration in human nutrition throughout life cycle with sex differences	32
The impact of gut microbiota metabolites on cellular bioenergetics and cardiometabolic health	29
Ferulic acid alleviates lipotoxicity-induced hepatocellular death through the SIRT1-regulated autophagy pathway and independently of AMPK and Akt in AML-12 hepatocytes	29
The anti-diabetic effects of betanin in streptozotocin-induced diabetic rats through modulating AMPK/SIRT1/NF-κB signaling pathway	28
The dysregulation of the hypothalamic–pituitary–adrenal axis in diet-induced prediabetic male Sprague Dawley rats	27
Prevalence and risk factors of metabolic associated fatty liver disease in the contemporary South China population	27
Dihydromyricetin ameliorates liver fibrosis via inhibition of hepatic stellate cells by inducing autophagy and natural killer cell-mediated killing effect	27
Hawthorn fruit extract reduced trimethylamine-N-oxide (TMAO)-exacerbated atherogenesis in mice via anti-inflammation and anti-oxidation	27
Gut microbiota modulation as a possible mediating mechanism for fasting-induced alleviation of metabolic complications: a systematic review	26
The role of protein hydrolysates for exercise-induced skeletal muscle recovery and adaptation: a current perspective	25
Sialylated human milk oligosaccharides prevent intestinal inflammation by inhibiting toll like receptor 4/NLRP3 inflammasome pathway in necrotizing enterocolitis rats	24
Metabolic reprogramming in cervical cancer and metabolomics perspectives	24
Validation of Dietary Antioxidant Index (DAI) and investigating the relationship between DAI and the odds of gastric cancer	23
Effects of NAD+ precursor supplementation on glucose and lipid metabolism in humans: a meta-analysis	22
Effects of exercise on high-fat diet–induced non-alcoholic fatty liver disease and lipid metabolism in ApoE knockout mice	22
Estradiol regulates intestinal ABCG2 to promote urate excretion via the PI3K/Akt pathway	22
Combined Lycium barbarum polysaccharides and C-phycocyanin increase gastric Bifidobacterium relative abundance and protect against gastric ulcer caused by aspirin in rats	21

Pineapple consumption reduced cardiac oxidative stress and inflammation in high cholesterol diet-fed rats	21
Aerobic exercise promotes the functions of brown adipose tissue in obese mice via a mechanism involving COX2 in the VEGF signaling pathway	21
Association between frequency of spicy food consumption and hypertension: a cross-sectional study in Zhejiang Province, China	19
Metabolic and hormonal effects of melatonin and/or magnesium supplementation in women with polycystic ovary syndrome: a randomized, double-blind, placebo-controlled trial	19
Menopausal status, age at natural menopause and risk of diabetes in China: a 10-year prospective study of 300,000 women	18
A combination of herbal compound (SPTC) along with exercise or metformin more efficiently alleviated diabetic complications through down-regulation of stress oxidative pathway upon activating Nrf2-Kea	18
The effect of high-fat diet and exercise on KISS-1/GPR54 expression in testis of growing rats	17
Independent and joint associations of body mass index, waist circumference, waist-height ratio and their changes with risks of hyperuricemia in middle-aged and older Chinese individuals: a population-	17
L-carnitine ameliorates the muscle wasting of cancer cachexia through the AKT/FOXO3a/MaFbx axis	17
The relation between low carbohydrate diet score and psychological disorders among Iranian adults	17
Extracellular water to total body water ratio predicts survival in cancer patients with sarcopenia: a multi-center cohort study	17
The long noncoding RNA MALAT1 modulates adipose loss in cancer-associated cachexia by suppressing adipogenesis through PPAR-γ	17
Fat mass to fat-free mass ratio and the risk of non-alcoholic fatty liver disease and fibrosis in non-obese and obese individuals	17
The effect of conjugated linoleic acids on inflammation, oxidative stress, body composition and physical performance: a comprehensive review of putative molecular mechanisms	16
Combined effect of vitamin C and vitamin D3 on intestinal epithelial barrier by regulating Notch signaling pathway	16
Metabolic adaptation is associated with less weight and fat mass loss in response to low-energy diets	16
Comparisons of the effects of different flaxseed products consumption on lipid profiles, inflammatory cytokines and anthropometric indices in patients with dyslipidemia related diseases: systematic re	16
Gut microbiome and stages of diabetes in middle-aged adults: CARDIA microbiome study	15
Beneficial effect of time-restricted eating on blood pressure: a systematic meta-analysis and meta-regression analysis	15
Visceral adiposity index outperforms conventional anthropometric assessments as predictor of diabetes mellitus in elderly Chinese: a population-based study	15
Sex- and body mass index-specific reference intervals for serum leptin: a population based study in China	15
Mulberry leaf extract improves glycaemic response and insulaemic response to sucrose in healthy subjects: results of a randomized, double blind, placebo-controlled study	14
Discovery of metabolic biomarkers for gestational diabetes mellitus in a Chinese population	14
Supplementation of quinoa regulates glycolipid metabolism and endoplasmic reticulum stress in the high-fat diet-induced female obese mice	14
Gastrodin ameliorates atherosclerosis by inhibiting foam cells formation and inflammation through down-regulating NF-κB pathway	13
Serum uric acid and risk of incident chronic kidney disease: a national cohort study and updated meta-analysis	12
Improvements in HOMA indices and pancreatic endocrinal tissues in type 2-diabetic rats by DPP-4 inhibition and antioxidant potential of an ethanol fruit extract of Withania coagulans	12
Inulin reduces visceral adipose tissue mass and improves glucose tolerance through altering gut metabolites	12
A comprehensive insight into the molecular and cellular mechanisms of the effects of Propolis on preserving renal function: a systematic review	12
Dihydromyricetin attenuates palmitic acid-induced oxidative stress by promoting autophagy via SIRT3-ATG4B signaling in hepatocytes	12
Combined treatment with glucosamine and chondroitin sulfate improves rheumatoid arthritis in rats by regulating the gut microbiota	12
Prevalence and prognostic significance of malnutrition in diabetic patients with coronary artery disease: a cohort study	12
Protective effect of homogeneous polysaccharides of Wuguchong (HPW) on intestinal mucositis induced by 5-fluorouracil in mice	12
L-theanine prevents progression of nonalcoholic hepatic steatosis by regulating hepatocyte lipid metabolic pathways via the CaMKKβ-AMPK signaling pathway	12
Differential ketogenic diet-induced shift in CSF lipid/carbohydrate metabolome of pediatric epilepsy patients with optimal vs. no anticonvulsant response: a pilot study	11
Association of daytime napping in relation to risk of diabetes: evidence from a prospective study in Zhejiang, China	11
1,25-Dihydroxyvitamin D3 modulates adipogenesis of human adipose-derived mesenchymal stem cells dose-dependently	11
Curcumin improves insulin sensitivity in high-fat diet-fed mice through gut microbiota	11
Alpha-linolenic acid inhibits hepatocellular carcinoma cell growth through Farnesoid X receptor/β-catenin signaling pathway	11
Sanziguben polysaccharides inhibit diabetic nephropathy through NF-κB-mediated anti-inflammation	11
Protective effects of calorie restriction on insulin resistance and islet function in STZ-induced type 2 diabetes rats	10
Effects of hawthorn seed oil on plasma cholesterol and gut microbiota	10
Integrative proteomic and lipidomic analysis of Kaili Sour Soup-mediated attenuation of high-fat diet-induced nonalcoholic fatty liver disease in a rat model	10
A nonlinear association of total cholesterol with all-cause and cause-specific mortality	10
Association between baseline and changes in high-sensitive C-reactive protein and metabolic syndrome: a nationwide cohort study and meta-analysis	10
Dietary curcumin supplementation promotes browning and energy expenditure in postnatal overfed rats	10
Association between baseline and changes in serum uric acid and incident metabolic syndrome: a nation-wide cohort study and updated meta-analysis	10
Sex differences in the relationships between body composition, fat distribution, and mitochondrial energy metabolism: a pilot study	10
Disease-associated metabolic alterations that impact satellite cells and muscle regeneration: perspectives and therapeutic outlook	10
Obesity and intestinal stem cell susceptibility to carcinogenesis	10

Combined intake of blueberry juice and probiotics ameliorate mitochondrial dysfunction by activating SIRT1 in alcoholic fatty liver disease	10
Dietary inflammatory index and metabolic syndrome in US children and adolescents: evidence from NHANES 2001–2018	10
Trends in prevalence of gestational diabetes mellitus in Zhejiang Province, China, 2016–2018	10
Anti-obesity effects of heat-transformed green tea extract through the activation of adipose tissue thermogenesis	9
A fifty percent leucine-restricted diet reduces fat mass and improves glucose regulation	9
Nerve growth factor is closely related to glucose metabolism, insulin sensitivity and insulin secretion in the second trimester: a case–control study in Chinese	9
Hyperuricemia as a prognostic marker for long-term outcomes in patients with myocardial infarction with nonobstructive coronary arteries	9
Association between dietary saturated fat with cardiovascular disease risk markers and body composition in healthy adults: findings from the cross-sectional BODYCON study	9
Association of whole blood copper, magnesium and zinc levels with metabolic syndrome components in 6–12-year-old rural Chinese children: 2010–2012 China National Nutrition and Health Survey	9
Impact of mixed meal tolerance test composition on measures of beta-cell function in type 2 diabetes	9
Metabolomic signatures for visceral adiposity and dysglycaemia in Asian Chinese and Caucasian European adults: the cross-sectional TOFI_Asia study	9
Protective and therapeutic effectiveness of taurine supplementation plus low calorie diet on metabolic parameters and endothelial markers in patients with diabetes mellitus: a randomized, clinical tri	9
High fat diet and PCSK9 knockout modulates lipid profile of the liver and changes the expression of lipid homeostasis related genes	9
Neck circumference as an independent predictor for NAFLD among postmenopausal women with normal body mass index	9
The deletion of glucagon-like peptide-1 receptors expressing neurons in the dorsomedial hypothalamic nucleus disrupts the diurnal feeding pattern and induces hyperphagia and obesity	9
Progression of atherosclerosis with carnitine supplementation: a randomized controlled trial in the metabolic syndrome	9
Association between iron metabolism and non-alcoholic fatty liver disease: results from the National Health and Nutrition Examination Survey (NHANES 2017–2018) and a controlled animal study	9
Longitudinal association between an overall diet quality index and latent profiles of cardiovascular risk factors: results from a population based 13-year follow up cohort study	9
The relationship of different levels of high iodine and goiter in school children: a meta-analysis	8
Modulation and bioinformatics screening of hepatic mRNA-lncRNAs (HML) network associated with insulin resistance in prediabetic and exercised mice	8
Edible red seaweed Campylaephora hypnaeoides J. Agardh alleviates obesity and related metabolic disorders in mice by suppressing oxidative stress and inflammatory response	8
Metabolomics and physiological analysis of the effect of calcium supplements on reducing bone loss in ovariectomized rats by increasing estradiol levels	8
The effect of DASH diet on glycemic response, meta-inflammation and serum LPS in obese patients with NAFLD: a double-blind controlled randomized clinical trial	8
Dietary nutrient intake related to higher grade cervical intraepithelial neoplasia risk: a Chinese population-based study	8
Caffeine improves biochemical and specific performance after judo training: a double-blind crossover study in a real judo training situation	8
Association of serum methionine metabolites with non-alcoholic fatty liver disease: a cross-sectional study	8
Changes in hepatic triglyceride content with the activation of ER stress and increased FGF21 secretion during pregnancy	8
Visceral adiposity index is associated with arterial stiffness in hypertensive adults with normal-weight: the china H-type hypertension registry study	8
Associations of starchy and non-starchy vegetables with risk of metabolic syndrome: evidence from the NHANES 1999–2018	8
Association between surrogate indicators of insulin resistance and risk of type 2 diabetes combined with hypertension among Chinese adults: two independent cohort studies	8
Food-specific serum IgG and symptom reduction with a personalized, unrestricted-calorie diet of six weeks in Irritable Bowel Syndrome (IBS)	8
The high dose of vitamin D supplementation combined with yoga training improve the leukocytes cell survival-related gene expression in breast cancer survivors	8
Alleviating the effect of quinoa and the underlying mechanism on hepatic steatosis in high-fat diet-fed rats	8
The combination of endurance exercise and SGTC (Salvia–Ginseng–Trigonella–Cinnamon) ameliorate mitochondrial markers’ overexpression with sufficient ATP production in the skeletal muscle of mice fed A	8
Antimicrobial treatment improves tryptophan metabolism and mood of patients with small intestinal bacterial overgrowth	7
TCF7L2 polymorphisms, nut consumption, and the risk of metabolic syndrome: a prospective population based study	7
Copper-catalyzed dicarbonyl stress in NAFLD mice: protective effects of Oleuropein treatment on liver damage	7
Serum biomarkers of the calcium-deficient rats identified by metabolomics based on UPLC/Q-TOF MS/MS	7
The association between dietary fats and the incidence risk of cardiovascular outcomes: Tehran Lipid and Glucose Study	7
The comparison of water intake patterns and hydration biomarkers among young adults with different hydration statuses in Hebei, China	7
Association between hypertension and coffee drinking based on CYP1A2 rs762551 single nucleotide polymorphism in Taiwanese	7
Magnesium isoglycyrrhizinate attenuates acute alcohol-induced hepatic steatosis in a zebrafish model by regulating lipid metabolism and ER stress	7
Association between breakfast skipping and metabolic outcomes by sex, age, and work status stratification	7
Association of serum choline levels and all-cause mortality risk in adults with hypertension: a nested case–control study	7
Diet-induced prediabetes: effects of exercise treatment on risk factors for cardiovascular complications	7
Anti-inflammatory and -apoptotic effects of a long-term herbal extract treatment on DSS-induced colitis in mice fed with high AGEs-fat diet	7
Exogenous L-carnitine ameliorates burn-induced cellular and mitochondrial injury of hepatocytes by restoring CPT1 activity	7
Ginger supplement significantly reduced length of hospital stay in individuals with COVID-19	7
Association between metabolically healthy overweight/obesity and gallstones in Chinese adults	7
METTL3 exacerbates insulin resistance in hepatocytes by regulating m6A modification of cytochrome P450 2B6	6
Pharmacotherapies of NAFLD: updated opportunities based on metabolic intervention	6
Effect of hydroalcoholic seed extract of Nigella sativa on hepatic and pancreatic factors of Nrf2 and FGF21 in the regulation of insulin transcription factors of MafA and PDX-1 in streptozotocin-treat	6
Influence of HFD-induced precocious puberty on neurodevelopment in mice	6
Androgen receptor regulates the proliferation of myoblasts under appropriate or excessive stretch through IGF-1 receptor mediated p38 and ERK1/2 pathways	6
Long-chain saturated fatty acid species are not toxic to human pancreatic β-cells and may offer protection against pro-inflammatory cytokine induced β-cell death	6
Prenatal inflammation causes obesity and abnormal lipid metabolism via impaired energy expenditure in male offspring	6
Association of serum calcium levels with renal impairment and all-cause death in Chinese patients with newly diagnosed multiple myeloma: a cross-sectional, longitudinal study	6
Effectiveness of companion-intensive multi-aspect weight management in Chinese adults with obesity: a 6-month multicenter randomized clinical trial	6
Chondroitin sulfate alleviates osteoporosis caused by calcium deficiency by regulating lipid metabolism	6
Proposal of a new equation for estimating resting energy expenditure of acute kidney injury patients on dialysis: a machine learning approach	6
The effect of iron dextran on vitamin D3 metabolism in SD rats	6
Associations of visceral adipose tissue with bone mineral density and fracture: observational and Mendelian randomization studies	6
Association between early-pregnancy serum C-peptide and risk of gestational diabetes mellitus: a nested case–control study among Chinese women	6
Effect of high-fat diet and empagliflozin on cardiac proteins in mice	6
Salvianolic acid B activates chondrocytes autophagy and reduces chondrocyte apoptosis in obese mice via the KCNQ1OT1/miR-128-3p/SIRT1 signaling pathways	6
Comprehensive evaluation of caloric restriction-induced changes in the metabolome profile of mice	5
Tandem Mass Tag-based quantitative proteomics analysis of metabolic associated fatty liver disease induced by high fat diet in mice	5
Two-year changes in body composition and future cardiovascular events: a longitudinal community-based study	5
Cholecalciferol supplementation lowers leptin and TMAO but increases NO and VEGF-A levels in obese vitamin D deficient patients: Is it one of the potential cardioprotective mechanisms of vitamin D?	5
Dihydromyricetin ameliorates diet-induced obesity and promotes browning of white adipose tissue by upregulating IRF4/PGC-1α	5
Lipidomic analysis of brain and hippocampus from mice fed with high-fat diet and treated with fecal microbiota transplantation	5
Angiotensin(1–7) attenuates visceral adipose tissue expansion and lipogenesis by suppression of endoplasmic reticulum stress via Mas receptor	5
Asiatic acid alleviates Ang-II induced cardiac hypertrophy and fibrosis via miR-126/PIK3R2 signaling	5
Coenzyme Q10 supplementation improves adipokine profile in dyslipidemic individuals: a randomized controlled trial	5
Vascular lipidomics analysis reveales increased levels of phosphocholine and lysophosphocholine in atherosclerotic mice	5
Is the urinary iodine/creatinine ratio applicable to assess short term individual iodine status in Chinese adults? Comparison of iodine estimates from 24-h urine and timed-spot urine samples in differ	5
Excessive fat expenditure in cachexia is associated with dysregulated circadian rhythm: a review	5
The role and possible mechanism of the long noncoding RNA LINC01260 in nonalcoholic fatty liver disease	4
Lotus leaf extract inhibits ER− breast cancer cell migration and metastasis	4
Perilipin5 protects against non-alcoholic steatohepatitis by increasing 11-Dodecenoic acid and inhibiting the occurrence of ferroptosis	4

A plant-based meal reduces postprandial oxidative and dicarbonyl stress in men with diabetes or obesity compared with an energy- and macronutrient-matched conventional meal in a randomized crossover s	4
Effect of individual- versus collective-based nutritional-lifestyle intervention on the atherogenic index of plasma in children with obesity: a randomized trial	4
The comparative anti-cancer effects of krill oil and oxaliplatin in an orthotopic mouse model of colorectal cancer	4
Unraveling the therapeutic efficacy of resveratrol in Alzheimer’s disease: an umbrella review of systematic evidence	4
The effect of dietary lipid quality in early life on serum LysoPC(18:2) levels and their association with adult blood glucose levels in intrauterine growth restricted rats	4
Dietary protein intake during pregnancy and birth weight among Chinese pregnant women with low intake of protein	4
Human nutritional relevance and suggested nutritional guidelines for vitamin A5/X and provitamin A5/X	4
An optimal glycemic load range is better for reducing obesity and diabetes risk among middle-aged and elderly adults	4
Associations of body shapes with insulin resistance and cardiometabolic risk in middle-aged and elderly Chinese	4
The role of diet and nutrition related indicators in biliary diseases: an umbrella review of systematic review and meta-analysis	4
Absolute quantitative lipidomics reveals lipids profiling in liver of mice with early-stage alcoholic liver disease	4
MicroRNA-302a is involved in folate deficiency-induced apoptosis through the AKT-FOXO1-BIM pathway in mouse embryonic stem cells	4
Weighted gene co-expression network analysis to identify key modules and hub genes related to hyperlipidaemia	3
The association between dietary quality scores with C-reactive protein and novel biomarkers of inflammation platelet-activating factor and lipoprotein-associated phospholipase A2: a cross-sectional st	3
Revisiting the interconnection between lipids and vitamin K metabolism: insights from recent research and potential therapeutic implications: a review	3
New insights into the nutritional genomics of adult-onset riboflavin-responsive diseases	3
Effect of lunch with different calorie and nutrient balances on dinner-induced postprandial glucose variability	3
The effects of a low carbohydrate diet combined with partial meal replacement on obese individuals	3
Effect of the lysosomotropic agent chloroquine on mTORC1 activation and protein synthesis in human skeletal muscle	3
Calcium channel blockers do not protect against saturated fatty acid-induced ER stress and apoptosis in human pancreatic β-cells	3
Maternal DHA-rich n-3 PUFAs supplementation interacts with FADS genotypes to influence the profiles of PUFAs in the colostrum among Chinese Han population: a birth cohort study	3
l-Arabinose improves hypercholesterolemia via regulating bile acid metabolism in high-fat-high-sucrose diet-fed mice	3
Effectiveness of a fortified drink in improving B vitamin biomarkers in older adults: a controlled intervention trial	3
Fluctuations in waist circumference increase diabetes risk: a 4-year cohort study in 61,587 older adults	3
Effects of increasing intake of soybean oil on synthesis of testosterone in Leydig cells	3
Snack consumption patterns and their associations with risk of incident metabolic syndrome: Tehran lipid and glucose study	3
Exploring the association of physical activity with the plasma and urine metabolome in adolescents and young adults	3
Development and validation of dietary and lifestyle insulinemic indices among Iranian adult population	3
Association between dietary antioxidant capacity and type 2 diabetes mellitus in Chinese adults: a population-based cross-sectional study	3
Dietary oxalate-calcium balance and the incidence of hypertension and chronic kidney disease: a prospective study among an Asian population	3
Amelioration of Atherosclerosis by lycopene is linked to the modulation of gut microbiota dysbiosis and related gut-heart axis activation in high-fat diet-fed ApoE−/− mice	3
High fructose induces dysfunctional vasodilatation via PP2A-mediated eNOS Ser1177 dephosphorylation	3
PA and OA induce abnormal glucose metabolism by inhibiting KLF15 in adipocytes	3
Ability of dietary factors to affect homocysteine levels in mice: a review	3