OOIR: Observatory of International Research

Papers

(The median citation count of Nanotoxicology is 4. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-11-01 to 2024-11-01.)

Article	Citations
8-Hydroxy-2′-deoxyguanosine (8-OHdG) as a biomarker of oxidative DNA damage induced by occupational exposure to nanomaterials: a systematic review	60
Interaction of nanoparticles with biological macromolecules: a review of molecular docking studies	54
Organ-specific toxicity of magnetic iron oxide-based nanoparticles	51
Nanoparticle-protein corona complex: understanding multiple interactions between environmental factors, corona formation, and biological activity	45
In vivo impact assessment of orally administered polystyrene nanoplastics: biodistribution, toxicity, and inflammatory response in mice	41
Toxicity of nanoplastics during the embryogenesis of the ascidian Ciona robusta (Phylum Chordata)	31
Efficient predictions of cytotoxicity of TiO₂-based multi-component nanoparticles using a machine learning-based q-RASAR approach	28
Multi-walled carbon nanotubes trigger lysosome-dependent cell death (pyroptosis) in macrophages but not in neutrophils	28
A methodology for developing key events to advance nanomaterial-relevant adverse outcome pathways to inform risk assessment	28
Microplastics and nanoplastics science: collecting and characterizing airborne microplastics in fine particulate matter	27
Biomedical nanomaterials: applications, toxicological concerns, and regulatory needs	25
Metallic-nanoparticle release systems for biomedical implant surfaces: effectiveness and safety	24
Occupational exposure to graphene and silica nanoparticles. Part II: pilot study to identify a panel of sensitive biomarkers of genotoxic, oxidative and inflammatory effects on suitable biological mat	24
Reactive oxygen species production, genotoxicity and telomere length in FE1-Muta™Mouse lung epithelial cells exposed to carbon nanotubes	23
Pulmonary toxicity of synthetic amorphous silica – effects of porosity and copper oxide doping	21
Intercellular transfer of mitochondria via tunneling nanotubes protects against cobalt nanoparticle-induced neurotoxicity and mitochondrial damage	21
Overview of potential adverse health effects of oral exposure to nanocellulose	20
Iron oxide nanoparticles aggravate hepatic steatosis and liver injury in nonalcoholic fatty liver disease through BMP-SMAD-mediated hepatic iron overload	20
Rationale and decision rules behind the ECETOC NanoApp to support registration of sets of similar nanoforms within REACH	20
In vivo percutaneous permeation of gold nanomaterials in consumer cosmetics: implication in dermal safety assessment of consumer nanoproducts	20
Time-course effect of ultrasmall superparamagnetic iron oxide nanoparticles on intracellular iron metabolism and ferroptosis activation	20
Antibacterial application and toxicity of metal–organic frameworks	19
Interaction of nanoparticles with endotoxin Importance in nanosafety testing and exploitation for endotoxin binding	19
Neutrophil activation by nanomaterials in vitro: comparing strengths and limitations of primary human cells with those of an immortalized (HL-60) cell line	19
Impact of copper oxide particle dissolution on lung epithelial cell toxicity: response characterization using global transcriptional analysis	18

Ecotoxicological assessment of commercial boron nitride nanotubes toward Xenopus laevis tadpoles and host-associated gut microbiota	17
Inhaled multi-walled carbon nanotubes differently modulate global gene and protein expression in rat lungs	16
Toxicity assessment of industrial engineered and airborne process-generated nanoparticles in a 3D human airway epithelial in vitro model	16
Carbon nanotubes promote alveolar macrophages toward M2 polarization mediated epithelial-mesenchymal transition and fibroblast-to-myofibroblast transdifferentiation	15
Surface atomic arrangement of nanomaterials affects nanotoxicity	15
Polystyrene nanoplastics exposure caused defective neural tube morphogenesis through caveolae-mediated endocytosis and faulty apoptosis	15
Polystyrene nanoparticles: the mechanism of their genotoxicity in human peripheral blood mononuclear cells	15
Stabilization of Nrf2 leading to HO-1 activation protects against zinc oxide nanoparticles-induced endothelial cell death	15
MMP-3 activation is involved in copper oxide nanoparticle-induced epithelial-mesenchymal transition in human lung epithelial cells	15
Unswerving modeling of hepatotoxicity of cadmium containing quantum dots using amalgamation of quasiSMILES, index of ideality of correlation, and consensus modeling	14
MiR-939-5p suppresses PM_2.5-induced endothelial injury via targeting HIF-1α in HAECs	14
Ambient PM2.5 exposure causes cellular senescence via DNA damage, micronuclei formation, and cGAS activation	14
Multiple pathways of alveolar macrophage death contribute to pulmonary inflammation induced by silica nanoparticles	14
Immunotoxic effects of metal-based nanoparticles in fish and bivalves	14
Amorphous silica nanoparticles caused lung injury through the induction of epithelial apoptosis via ROS/Ca ²⁺ /DRP1-mediated mitochondrial fission signaling	12
Machine learning predictions of concentration-specific aggregate hazard scores of inorganic nanomaterials in embryonic zebrafish	12
Toxicological effects of zinc oxide nanoparticle exposure: an in vitro comparison between dry aerosol air-liquid interface and submerged exposure systems	12
Role of necroptosis of alveolar macrophages in acute lung inflammation of mice exposed to titanium dioxide nanoparticles	12
Assessment of primary and inflammation-driven genotoxicity of carbon black nanoparticles in vitro and in vivo	12
Creating sets of similar nanoforms with the ECETOC NanoApp: real-life case studies	12
Manganese dioxide nanosheets induce mitochondrial toxicity in fish gill epithelial cells	12
Lipid peroxidation metabolites associated with biomarkers of inflammation and oxidation stress in workers handling carbon nanotubes and metal oxide nanoparticles	11
Combination effect of nanoparticles on the acute pulmonary inflammogenic potential: additive effect and antagonistic effect	10
Distribution of gold nanoparticles into the brain: a systematic review and meta-analysis	10
A harmonized protocol for an international multicenter prospective study of nanotechnology workers: the NanoExplore cohort	10
Broiler welfare is preserved by long-term low-dose oral exposure to zinc oxide nanoparticles: preliminary study	10
Integrated approaches to testing and assessment for grouping nanomaterials following dermal exposure	10
Use of single particle ICP-MS to estimate silver nanoparticle penetration through baby porcine mucosa	10
The influence of exposure approaches to in vitro lung epithelial barrier models to assess engineered nanomaterial hazard	10
PM_2.5 induce the defective efferocytosis and promote atherosclerosis via HIF-1α activation in macrophage	10
Perinatal exposure to silver nanoparticles reprograms immunometabolism and promotes pancreatic beta-cell death and kidney damage in mice	10
Metabolomics screening of serum biomarkers for occupational exposure of titanium dioxide nanoparticles	9
Enhanced antioxidant capacity prevents epitranscriptomic and cardiac alterations in adult offspring gestationally-exposed to ENM	8
NiONPs-induced alteration in calcium signaling and mitochondrial function in pulmonary artery endothelial cells involves oxidative stress and TRPV4 channels disruption	8
Assessing regulated cell death modalities as an efficient tool for in vitro nanotoxicity screening: a review	8
Acute exposure to C60 fullerene damages pulmonary mitochondrial function and mechanics	8
Ferritinophagy was involved in long-term SiNPs exposure induced ferroptosis and liver fibrosis	8
A methodology for the automatic evaluation of data quality and completeness of nanomaterials for risk assessment purposes	8
Amino-nanopolystyrene exposures of oyster (Crassostrea gigas) embryos induced no apparent intergenerational effects	8
Algal extracellular polymeric substances (algal-EPS) for mitigating the combined toxic effects of polystyrene nanoplastics and nano-TiO₂ in Chlorella sp.	8
Modeling and mechanistic understanding of cytotoxicity of metal oxide nanoparticles (MeOxNPs) to Escherichia coli: categorization and data gap filling for untested metal oxides	7
In vitro effects of cobalt and chromium nanoparticles on human platelet function	7
Engineered aluminum nanoparticle induces mitochondrial deformation and is predicated on cell phenotype	7
Nano-read-across predictions of toxicity of metal oxide engineered nanoparticles (MeOx ENPS) used in nanopesticides to BEAS-2B and RAW 264.7 cells	7
Food-grade titanium dioxide translocates across the buccal mucosa in pigs and induces genotoxicity in an in vitro model of human oral epithelium	7
Treatment of copper nanoparticles (CuNPs) for two spermatogenic cycles impairs testicular activity via down-regulating steroid receptors and inhibition of germ cell proliferation in a mice model	7
Comparative assessments of the biodistribution and toxicity of oxidized single-walled carbon nanotubes dispersed with two different reagents after intravenous injection	6
‘Trojan-Horse’ stress-granule formation mediated by manganese oxide nanoparticles	6
Transgenic zebrafish larvae as a non-rodent alternative model to assess pro-inflammatory (neutrophil) responses to nanomaterials	6
Nickel nanoparticles induce epithelial-mesenchymal transition in human bronchial epithelial cells via the HIF-1α/HDAC3 pathway	6

Graphene oxide influence in soil bacteria is dose dependent and changes at osmotic stress: growth variation, oxidative damage, antioxidant response, and plant growth promotion traits of a	6
Predicting the toxicity of nanoparticles using artificial intelligence tools: a systematic review	6
Silver nanoparticles suppress forskolin-induced syncytialization in BeWo cells	6
Some data on the comparative and combined toxic activity of nanoparticles containing lead and cadmium with special attention to their vasotoxicity	6
Comparative study of the transcriptomes of Caco-2 cells cultured under dynamic vs. static conditions following exposure to titanium dioxide and zinc oxide nanomaterials	6
Bioinspired silk fibroin nano-delivery systems protect against 5-FU induced gastrointestinal mucositis in a mouse model and display antitumor effects on HT-29 colorectal cancer cells in vitro	6
In vitro and in silico study of mixtures cytotoxicity of metal oxide nanoparticles to Escherichia coli : a mechanistic	5
Determination of the LD₅₀ with the chick embryo chorioallantoic membrane (CAM) assay as a promising alternative in nanotoxicological evaluation	5
Size effect and mucus role on the intestinal toxicity of the E551 food additive and engineered silica nanoparticles	5
Separating toxicity and shading in algal growth inhibition tests of nanomaterials and colored substances	5
Proteome-wide analysis reveals molecular pathways affected by AgNP in a ROS-dependent manner	5
The effect of natural biomolecules on yttrium oxide nanoparticles from a Daphnia magna survival rate perspective	5
Evaluation of graphene-derived bone scaffold exposure to the calvarial bone_in-vitro and in-vivo studies	5
Genotoxic hazard assessment of cerium oxide and magnesium oxide nanoparticles in Drosophila	5
Genotoxicity assessment of titanium dioxide nanoparticles using a standard battery of in vivo assays	4
Needlelike, short and thin multi-walled carbon nanotubes: comparison of effects on wild type and p53^+/− rat lungs	4
Exploring graphene-based materials’ genotoxicity: inputs of a screening method	4
Iron oxide nanoparticles cause surface coating- and core chemistry-dependent endothelial cell ferroptosis	4
Preclinical evaluation of early multi-organ toxicity induced by liposomal doxorubicin using ⁶⁷Ga-citrate	4
Deducing the cellular mechanisms associated with the potential genotoxic impact of gold and silver engineered nanoparticles upon different lung epithelial cell lines in vitro	4
Biodynamics and adverse effects of CuO nanoparticles and CuCl₂ in the oligochaete T. tubifex: Cu form influence biodynamics in water, but not sediment	4
Dependence of diamond nanoparticle cytotoxicity on physicochemical parameters: comparative studies of glioblastoma, breast cancer, and hepatocellular carcinoma cell lines	4
Developing Integrated Approaches for Testing and Assessment (IATAs) in order to support nanomaterial safety	4
Mutagenicity of silver nanoparticles evaluated using whole-genome sequencing in mouse lymphoma cells	4
Effects of dietary exposure to the engineered nanomaterials CeO₂, SiO₂, Ag, and TiO₂ on the murine gut microbiome	4
Predicting the cytotoxicity of nanomaterials through explainable, extreme gradient boosting	4
Developmental neurotoxicity of silver nanoparticles: the current state of knowledge and future directions	4
Impacts of ingested MWCNT-Embedded nanocomposites in Japanese medaka (Oryzias latipes)	4
Gestational exposure to silver nanoparticles enhances immune adaptation and protection against streptozotocin-induced diabetic nephropathy in mice offspring	4
Issues currently complicating the risk assessment of synthetic amorphous silica (SAS) nanoparticles after oral exposure	4