OOIR: Observatory of International Research

Papers

(The median citation count of Nanotoxicology is 3. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-05-01 to 2025-05-01.)

Article	Citations
Impact of polyethylene nanoplastics on human intestinal cells	73
The effect of natural biomolecules on yttrium oxide nanoparticles from a Daphnia magna survival rate perspective	56
In vivo assessment of topically applied silver nanoparticles on entire cornea: comprehensive FTIR study	47
Probing the effects of dextran-coated CeO ₂ nanoparticles on lung fibroblasts using multivariate single-cell Raman spectroscopy	36
In vivo impact assessment of orally administered polystyrene nanoplastics: biodistribution, toxicity, and inflammatory response in mice	35
Size effect and mucus role on the intestinal toxicity of the E551 food additive and engineered silica nanoparticles	31
8-Hydroxy-2′-deoxyguanosine (8-OHdG) as a biomarker of oxidative DNA damage induced by occupational exposure to nanomaterials: a systematic review	26
Cabazitaxel-loaded poly(alkyl cyanoacrylate) nanoparticles: Toxicity and changes in the proteome of breast, colon and prostate cancer cells	25
Comparative study of the transcriptomes of Caco-2 cells cultured under dynamic vs. static conditions following exposure to titanium dioxide and zinc oxide nanomaterials	22
Effects of titanium oxide nanoparticles on growth, biochemical composition, and photosystem mechanism of marine microalgae Isochrysis galbana COR-A3	19
Intercellular transfer of mitochondria via tunneling nanotubes protects against cobalt nanoparticle-induced neurotoxicity and mitochondrial damage	18
Biokinetics of carbon black, multi-walled carbon nanotubes, cerium oxide, silica, and titanium dioxide nanoparticles after inhalation: a review	18
Study on myocardial toxicity induced by lead halide perovskites nanoparticles	18
Food-grade titanium dioxide (E171) and zinc oxide nanoparticles induce mitochondrial permeability and cardiac damage after oral exposure in rats	18
Unswerving modeling of hepatotoxicity of cadmium containing quantum dots using amalgamation of quasiSMILES, index of ideality of correlation, and consensus modeling	17
The influence of exposure approaches to in vitro lung epithelial barrier models to assess engineered nanomaterial hazard	17
Analysis of carbon nanotube levels in organic matter: an inter-laboratory comparison to determine best practice	16
NiONPs-induced alteration in calcium signaling and mitochondrial function in pulmonary artery endothelial cells involves oxidative stress and TRPV4 channels disruption	16
Nickel nanoparticles induce epithelial-mesenchymal transition in human bronchial epithelial cells via the HIF-1α/HDAC3 pathway	15
Bioaccumulation of BDE47 in testes by TiO₂ nanoparticles aggravates the reproductive impairment of male zebrafish by disrupting intercellular junctions	15
Evaluation of cytotoxicity and biodistribution of mesoporous carbon nanotubes (pristine/-OH/-COOH) to HepG2 cells in vitro and healthy mice in vivo	14
Statement of Retraction: Contribution of nano-copper particles to in vivo liver dysfunction and cellular damage: Role of IκBα/NF-κB, MAPKs and mitochondrial signal	14
On how titanium dioxide nanoparticles attenuate the toxicity of mercuric chloride to Artemia salina : investigation of fatty acid composition, oxidative stress, and lipi	14
Correction	13
Assessment of primary and inflammation-driven genotoxicity of carbon black nanoparticles in vitro and in vivo	12

CoCrMo nanoparticle induces neurotoxicity mediated via mitochondrial dysfunction: a study model for implant derived nanoparticle effects	12
In vitro effects of combustion generated carbon dots on cellular parameters in healthy and cancerous breast cells	12
Assessing regulated cell death modalities as an efficient tool for in vitro nanotoxicity screening: a review	12
Role of physicochemical properties in silica nanoparticle-mediated immunostimulation	12
Recent trends and advancement in metal oxide nanoparticles for the degradation of dyes: synthesis, mechanism, types and its application	11
Multi-walled carbon nanotubes induce arachidonate 5-lipoxygenase expression and enhance the polarization and function of M1 macrophages in vitro	11
Toxicity study of pro-angiogenic casein manganese oxide nanoparticles: an in vitro and in vivo approach	11
Issues currently complicating the risk assessment of synthetic amorphous silica (SAS) nanoparticles after oral exposure	10
Predicting the toxicity of nanoparticles using artificial intelligence tools: a systematic review	10
Silver nanoparticles suppress forskolin-induced syncytialization in BeWo cells	10
Potent lung tumor promotion by inhaled MWCNT	10
Algal extracellular polymeric substances (algal-EPS) for mitigating the combined toxic effects of polystyrene nanoplastics and nano-TiO₂ in Chlorella sp.	10
Treatment of copper nanoparticles (CuNPs) for two spermatogenic cycles impairs testicular activity via down-regulating steroid receptors and inhibition of germ cell proliferation in a mice model	9
Modulating exosomal communication between macrophages and melanoma cancer cells via cyclodextrin-based nanosponges loaded with doxorubicin	9
Transgenic zebrafish larvae as a non-rodent alternative model to assess pro-inflammatory (neutrophil) responses to nanomaterials	9
Biomarkers of oxidative stress in urine and plasma of operators at six Singapore printing centers and their association with several metrics of printer-emitted nanoparticle exposures	9
Preclinical evaluation of early multi-organ toxicity induced by liposomal doxorubicin using ⁶⁷Ga-citrate	9
Ferritinophagy was involved in long-term SiNPs exposure induced ferroptosis and liver fibrosis	8
Lung toxicity, deposition, and clearance of thermal spray coating particles with different metal profiles after inhalation in rats	8
Acute hazard assessment of silver nanoparticles following intratracheal instillation, oral and intravenous injection exposures	8
Harmonizing nanomaterial exposure methodologies in ecotoxicology: the effects of two innovative nanoclays in the freshwater microalgae Raphidocelis subcapitata	8
Modeling and mechanistic understanding of cytotoxicity of metal oxide nanoparticles (MeOxNPs) to Escherichia coli: categorization and data gap filling for untested metal oxides	7
Systematic review of mechanistic evidence for TiO ₂ nanoparticle-induced lung carcinogenicity	7
Developmental neurotoxicity of silver nanoparticles: the current state of knowledge and future directions	7
Use of single particle ICP-MS to estimate silver nanoparticle penetration through baby porcine mucosa	7
Correction	7
Multiple pathways of alveolar macrophage death contribute to pulmonary inflammation induced by silica nanoparticles	7
Artificial augmented dataset for the enhancement of nano-QSARs models. A methodology based on topological projections	6
Interaction between polydopamine-based IONPs and human serum albumin (HSA): a spectroscopic analysis with cytotoxicity impact	6
Needlelike, short and thin multi-walled carbon nanotubes: comparison of effects on wild type and p53^+/− rat lungs	6
Application of carbon nanostructures in biomedicine: realities, difficulties, prospects	6
Biokinetics of inhaled silver, gold, copper oxide, and zinc oxide nanoparticles: a review	6
Quantitative adverse outcome pathway (qAOP) using bayesian network model on comparative toxicity of multi-walled carbon nanotubes (MWCNTs): safe-by-design approach	6
Enhanced antioxidant capacity prevents epitranscriptomic and cardiac alterations in adult offspring gestationally-exposed to ENM	6
A methodology for the automatic evaluation of data quality and completeness of nanomaterials for risk assessment purposes	6
An analysis on control banding-based methods used for occupational risk assessment of nanomaterials	6
Genotoxicity assessment of titanium dioxide nanoparticles using a standard battery of in vivo assays	5
Effect of titanium dioxide nanoparticles on histone modifications and histone modifying enzymes expression in human cell lines	5
Protein interaction, monocyte toxicity and immunogenic properties of cerium oxide crystals with 5% or 14% gadolinium, cobalt oxide and iron oxide nanoparticles – an interdisciplinary approach	5
Investigation of the effects of nanoplastic polyethylene terephthalate on environmental toxicology using model Drosophila melanogaster	5
Iron oxide nanoparticles aggravate hepatic steatosis and liver injury in nonalcoholic fatty liver disease through BMP-SMAD-mediated hepatic iron overload	5
Assessment of genotoxicity induced by subchronic exposure to graphene in HaCaT human skin cell line	5
MiR-939-5p suppresses PM_2.5-induced endothelial injury via targeting HIF-1α in HAECs	5
HMGB1 derived from lung epithelial cells after cobalt nanoparticle exposure promotes the activation of lung fibroblasts	5
Bioinspired silk fibroin nano-delivery systems protect against 5-FU induced gastrointestinal mucositis in a mouse model and display antitumor effects on HT-29 colorectal cancer cells in vitro	4
Protective effects of quercetin on intestinal barrier and cellular viability against silver nanoparticle exposure: insights from an intestinal co-culture model	4
Photocatalytic activity of nanoparticles: the development of the standardized measurement for physiological conditions	4
Chitosan functionalization of metal- and carbon-based nanomaterials as an approach toward sustainability tomorrow	4
Polyethyleneimine/polyethylene glycol–conjugated gold nanoparticles as nanoscale positive/negative controls in nanotoxicology: testing in frog embryo teratogenesis assay–Xenopusand mammalian ti	4
Developing Integrated Approaches for Testing and Assessment (IATAs) in order to support nanomaterial safety	4

A harmonized protocol for an international multicenter prospective study of nanotechnology workers: the NanoExplore cohort	4
Role of necroptosis of alveolar macrophages in acute lung inflammation of mice exposed to titanium dioxide nanoparticles	4
Immunological properties of silica nanoparticles: a structure–activity relationship study	4
Cytotoxic evaluation of pure and doped iron oxide nanoparticles on cancer cells: a magnetic fluid hyperthermia perspective	4
Nano-read-across predictions of toxicity of metal oxide engineered nanoparticles (MeOx ENPS) used in nanopesticides to BEAS-2B and RAW 264.7 cells	4
Overview of potential adverse health effects of oral exposure to nanocellulose	4
Intraperitoneal hepatorenal toxicity of zinc oxide and nickel oxide nanoparticles in rats: a systematic review	4
Creating sets of similar nanoforms with the ECETOC NanoApp: real-life case studies	3
Development and evaluation of cell membrane-based biomimetic nanoparticles loaded by Clostridium perfringens epsilon toxin: a novel vaccine delivery platform for	3
Quantifying uncertainty in dose–response screenings of nanoparticles: a Bayesian data analysis	3
The nanotoxicity assessment of cube-like iron nitride magnetic nanoparticles at the organismal level of nematode Caenorhabditis elegans	3
MiR-5622-3p inhibits ZCWPW1 to induce apoptosis in silica-exposed mice and spermatocyte cells	3
Exploring graphene-based materials’ genotoxicity: inputs of a screening method	3
Comparison of uptake and elimination kinetics of metallic oxide nanomaterials on the freshwater microcrustacean Daphnia magna	3
Deducing the cellular mechanisms associated with the potential genotoxic impact of gold and silver engineered nanoparticles upon different lung epithelial cell lines in vitro	3
Evaluating the antibacterial efficacy of a silver nanocomposite surface coating against nosocomial pathogens as an antibiofilm strategy to prevent hospital infections	3
Food-grade titanium dioxide translocates across the buccal mucosa in pigs and induces genotoxicity in an in vitro model of human oral epithelium	3
Comparative assessments of the biodistribution and toxicity of oxidized single-walled carbon nanotubes dispersed with two different reagents after intravenous injection	3
Predicting the cytotoxicity of nanomaterials through explainable, extreme gradient boosting	3
Separating toxicity and shading in algal growth inhibition tests of nanomaterials and colored substances	3
Ambient PM2.5 exposure causes cellular senescence via DNA damage, micronuclei formation, and cGAS activation	3
Dependence of diamond nanoparticle cytotoxicity on physicochemical parameters: comparative studies of glioblastoma, breast cancer, and hepatocellular carcinoma cell lines	3