Basic & Clinical Pharmacology & Toxicology

Article	Citations
Register‐based study on prescription renewal without the prescriber meeting the patient	165
Involvement of the effect of renal hypoperfusion medications on vancomycin trough concentration: A secondary analysis using a retrospective observational data	161
Triangulation of pharmacoepidemiology and laboratory science to tackle otic quinolone safety	93
Copper fabric improves the metabolic profile of obese mice: Potential role of the gut microbiota	59
Issue Information	48
Incidence in pharmacoepidemiology—Basic definitions and types of misclassification	45
Assessment of drug–drug interactions between moxonidine and antiepileptic drugs in the maximal electroshock seizure test in mice	38
A two‐decade review of butane toxicity as a substance of abuse	37
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Pharmacogenetic testing to guide therapeutic decision‐making and improve outcomes for children undergoing anthracycline‐based chemotherapy	29
Antibiotic treatment of community‐acquired pneumonia: A questionnaire survey in Danish general practice	27
How does deprescribing (not) reduce mortality? A review of a meta‐analysis in community‐dwelling older adults casts uncertainty over claimed benefits	22
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Lithium and the risk of chronic kidney disease: A population‐based case–control study	20
Efficacy of fibroblast growth factor 21 in non‐alcoholic fatty liver disease in guinea pigs	18
Clinical predictors of nephrotoxicity associated with teicoplanin: Meta‐analysis and meta‐regression	17
Matrix metalloproteinases are associated with severity of disease among COVID‐19 patients: A possible pharmacological target	17
Role of Inflammatory and Proresolving Mediators in Endothelial Dysfunction	16
Targeting of cancer cell death mechanisms by curcumin: Implications to cancer therapy	16
Issue Information	15
Artesunate alleviates intracerebral haemorrhage secondary injury by inducing ferroptosis in M1‐polarized microglia and suppressing inflammation through AMPK/mTORC1/GPX4 pathway	15
Methadone pharmacokinetics in opioid agonist treatment: Influencing factors and clinical implications	14
Risk of muscle toxicity events for daptomycin with and without statins: Analysis of the Japanese Adverse Event Report database	14
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Vitamin D and SARS‐CoV‐2	13
The Patient Typology about deprescribing and medication‐related decisions: A quantitative exploration	13
Pregnane X receptor activation induces liver enlargement and regeneration and simultaneously promotes the metabolic activity of CYP3A1/2 and CYP2C6/11 in rats	13
Preclinical safety and biodistribution assessment of Ad‐KCNH2‐G628S administered via atrial painting in New Zealand white rabbits	13
A characterization of patients with low soluble urokinase plasminogen activator receptor who died within 90 days of hospital discharge	12
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Decreased blood pressure with acute administration of quercetin in L‐NAME‐induced hypertensive rats	12
The alleviatory effects of koumine on MSU‐induced gouty arthritis via the TLR4/NF‐κB/NLRP3 pathway	12
Medication use among the oldest old in the Faroe Islands—A national cross‐sectional study	12
Drug metabolism and drug transport of the 100 most prescribed oral drugs	11
Chronic mercury exposure induces oxidative stress in female rats by endothelial nitric oxide synthase uncoupling and cyclooxygenase‐2 activation, without affecting oestrogen receptor function	11
Increased Mitochondrial Superoxide Level Is Partially Associated With Vemurafenib‐Induced Renal Tubular Toxicity	11
Cytotoxicity, genotoxicity and mutagenicity of mixed ternary mononuclear Mg complex based on valproic acid with 1,10‐phenanthroline in Saccharomyces cerevisiae and V79 cells	11
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Leaky lessons learned: Efflux prone dopamine transporter variant reveals sex and circuit specific contributions of D2 receptor signalling to neuropsychiatric disease	11
Sapanisertib attenuates pulmonary fibrosis by modulating Wnt5a/mTOR signalling	11
Role of cytochrome P450 2C8 genetic polymorphism and epoxygenase uncoupling in periodontal remodelling affecting orthodontic treatment	11
Issue Information	11
Possible opioid‐saving effect of cannabis‐based medicine using individual‐based data from the Norwegian Prescription Database	11
Prescribing and deprescribing trends in schizophrenia: An overview of inpatients in Belgium and in the Canadian province of Québec	10
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Effects of organic chemicals from diesel exhaust particles on adipocytes differentiated from human mesenchymal stem cells	10
Metabolism studies of 4′Cl‐CUMYL‐PINACA, 4′F‐CUMYL‐5F‐PINACA and 4′F‐CUMYL‐5F‐PICA using human hepatocytes and LC‐QTOF‐MS analysis	10
Fluvoxamine Inhibited NLRP3 and NF‐κB Inflammatory Pathways and Maintained Genital Functions by Ameliorating CD‐MPR, KISS‐1, AQP4 and Claudin‐1 Expressions	10
Copper: From enigma to therapeutic target for neurological disorder	10
Drugs targeting APOE4 that regulate beta‐amyloid aggregation in the brain: Therapeutic potential for Alzheimer's disease	10
Risk of kidney injury in patients on concomitant oral vancomycin and piperacillin‐tazobactam: Analysis of the pharmacovigilance database in Japan	10
Issue Information	9
Corrigendum	9
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ChatGPT: First glance from a perspective of clinical pharmacology	9
A novel flowchart to predict mortality and analyse effectiveness of routinely used pharmacological regimens in paraquat poisoning	9
Translational aspects of cytochrome P450‐mediated drug–drug interactions: A case study with clopidogrel	9
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Further perspectives on statin use in patients with chronic kidney disease	9
Potential drug‐drug interactions in acute poisonings managed in the intensive care unit: Occurrence, risk factors and relationship to patient severity on admission	9
Effects of quercetin on ovarian function and regulation of the ovarian PI3K/Akt/FoxO3a signalling pathway and oxidative stress in a rat model of cyclophosphamide‐induced premature ovarian failure	9
Effects of Zuojin Pill (Rhizoma CoptidisandFructus Evodiaepreparation) on the pharmacokinetics and side effects of venlafaxine in humans	9
The stimulant cathine from Khat causes tachycardia indirectly in the rat	9
Effect of Roux‐en‐Y gastric bypass on the pharmacokinetic‐pharmacodynamic relationships of liquid and controlled‐release formulations of oxycodone	9
Issue Information	9
Exosomal lncRNA HOTAIR promotes osteoclast differentiation by targeting TGF‐β/PTHrP/RANKL pathway	9
Effect of dexmedetomidine on oxytocin‐induced uterine contraction during optimal caesarean section anaesthesia	8
Effects of GLP‐1 Receptor Agonists in Alcohol Use Disorder	8
Issue Information	8
Letter from the editor	8
BCPT 2024 Prizes and Awards	8
Ameliorative Role of β‐Caryophyllene on Antioxidant Biomarkers in a Paroxetine‐Induced Model of Male Sexual Dysfunction	8
Role of bradykinin and prostaglandin EP4 receptors in regulating TRPV1 channel sensitization in rat dorsal root ganglion neurons	8
The state of deprescribing research: How did we get here?	8

Optimizing autophagy modulation for enhanced TRAIL‐mediated therapy: Unveiling the superiority of late‐stage inhibition over early‐stage inhibition to overcome therapy resistance in cancer	8
Advancing deprescribing: Learnings from the first international conference on deprescribing	8
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Changes in oral corticosteroid use in asthma treatment—A 20‐year Danish nationwide drug utilisation study	7
In vitro effect of hyoscine‐N‐butyl bromide and diclofenac sodium in human tuba uterina	7
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Making it happen: Development of an interprofessional deprescribing education programme	7
Inappropriate polypharmacy management versus deprescribing: A review on their relationship	7
Correction to Involvement of H2S, NO and BDNF‐TrkB signalling pathway in the protective effects of simvastatin against pentylenetetrazole‐induced kindling and cognitive impairments in mice	7
Issue Information	7
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First‐in‐human study with ACT‐1014‐6470, a novel oral complement factor 5a receptor 1 (C5aR1) antagonist, supported by pharmacokinetic predictions from animals to patients	7
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Deprescribing in primary care without deterioration of health‐related outcomes: A real‐life, quality improvement project	7
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Individual susceptibility has a major impact on strong association between oxidative stress, defence systems and Parkinson's disease	7
Pro‐inflammatory cytokines/chemokines, TNF‐α, IL‐6 and MCP‐1, as biomarkers for the nephro‐ and pneumoprotective effect of silibinin after hepatic ischemia/reperfusion: Confirmation by immunohistochem	7
Four weeks SGLT2 inhibition improves beta cell function and glucose tolerance without affecting muscle free fatty acid or glucose uptake in subjects with type 2 diabetes	6
Dose safety and pharmacodynamics of subcutaneous bupivacaine in a novel extended‐release microparticle formulation: A phase 1, dose‐ascending study in male volunteers	6
Disease activity and therapeutic drug monitoring of polyglutamates of methotrexate after daily or weekly administration of low‐dose methotrexate in patients recently diagnosed with rheumatoid arthriti	6
The Molecular and Clinical Impact of Atorvastatin Exposure on Paclitaxel Neurotoxicity in Sensory Neurons and Cancer Patients	6
Erratum	6
Issue Information	6
Persistence to statin treatment: A cohort study in Lithuania	6
Issue Information	6
Methylophiopogonanone A is a naturally occurring broad‐spectrum inhibitor against human UDP‐glucuronosyltransferases: Inhibition behaviours and implication in herb‐drug interactions	6
Issue Information	6
Somatostatin receptor ligands suppressed proliferation and lipogenesis in 3T3‐L1 preadipocytes	6
Issue Information	6
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Effects of rifampicin on porphyrin metabolism in healthy volunteers	6
Mechanistic insights into the pathogenesis of microtubule‐targeting agent‐induced peripheral neuropathy from pharmacogenetic and functional studies	6
Atenolol and mortality events in patients with chronic kidney disease: Analysis of data from the Japanese Adverse Drug Event Report database	5
The Pathobiology of Cerebrovascular Lesions in CADASIL Small Vessel Disease	5
Therapeutic benefit of melatonin in 5‐fluorouracil‐induced renal and hepatic injury	5
Gentiopicroside Attenuated Dopaminergic Neurodegeneration via Inhibiting Neuroinflammatory Responses and Ferroptosis in Experimental Models of Parkinson's Disease	5
Welcome to Basic & Clinical Pharmacology & Toxicology 2024	5
Ten deprescribing articles you should know about: A guide for newcomers to the field	5
Multiple regulation and targeting effects of borneol in the neurovascular unit in neurodegenerative diseases	5
Efficacy of weekly versus daily cholecalciferol for repleting serum vitamin D (25(OH)D) deficiency: A systematic review and meta‐analysis of randomized controlled trials	5
Berberine regulates pulmonary inflammatory microenvironment and decreases collagen deposition in response to bleomycin‐induced pulmonary fibrosis in mice	5
Downregulation of GPR160 inhibits the progression of glioma through suppressing epithelial to mesenchymal transition (EMT) biomarkers	5
The effectiveness and safety of botulinum toxin injections for managing motor disorders of patients with Parkinson's disease: A meta‐analysis of randomized controlled trials	5
Categorization of deprescribing communication tools: A scoping review	5
Growth differentiation factor 15 is dispensable for acetaminophen‐induced liver injury in mice	5
Issue Information	5
A review on the new age methodologies for early detection of Alzheimer's and Parkinson's disease	5
Toxicity and therapy outcome associations in LIG3, SLCO1B3, ABCB1, OPRM1 and GSTP1 in high‐grade serous ovarian cancer	5
Corrigendum	5
Deaths caused by medication in persons not using illicit narcotic drugs: An autopsy study from Western Denmark	5
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Dementia and neurodegenerative diseases: What is known and what is promising at the cellular and molecular level	5
Issue Information	5
Exploratory pharmacovigilance with machine learning in big patient data: A focused scoping review	5
Studies on the mode of action of synthetic diindolylmethane derivatives against triple negative breast cancer cells	5
Biomarkers of Parkinson's disease in perspective of early diagnosis and translation of neurotrophic therapies	5
Traditional Chinese Medicine for Inhibiting Ferroptosis in Ischemic‐Related Diseases	5
Foetal Exposure to Phthalates and Endocrine Effects on the Leydig Cell	5
Association between patient attitudes towards deprescribing and subsequent prescription changes	5
Pharmacokinetics of free and total mycophenolic acid in paediatric and adult renal transplant recipients: Exploratory analysis of the effects of clinical factors and gene variants	5
High Throughput Pharmacovigilance Screening for Roflumilast Adverse Effects in Real‐World Settings: A Sequence Symmetry Analysis	5
Effect of stearyl alcohol on imiquimod‐induced psoriasis‐like skin inflammation in mice	5
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Paroxetine alleviates ulcerative colitis in mice via restoring intestinal microbiota homeostasis and metabolism	5
Plasma NGAL, suPAR, KIM‐1 and GDF‐15 for Improving Glomerular Filtration Rate Estimation in Older Hospitalized Patients	5
Issue Information	5
Rapid‐acting antidepressants and the regulation of TrkB neurotrophic signalling—Insights from ketamine, nitrous oxide, seizures and anaesthesia	5
The BCPT young researcher Nordic Prize 2022 goes to Associate Professor Tore Bjerregaard Stage	4
Disease‐modifying therapies in multiple sclerosis: A focused review of rituximab	4
Initiation of Anticoagulants During the COVID‐19 Pandemic in Sweden: An Interrupted Time Series Analysis	4
Antitumour effect of odoroside A and its derivative on human leukaemia cells through the ROS/JNK pathway	4
Triptolide alleviates collagen‐induced arthritis in mice by modulating Treg/Th17 imbalance through the JAK/PTEN‐STAT3 pathway	4
CYP3A4*22 and bleeding risk in ticagrelor users	4
Issue Information	4
Study of the mechanism underlying the role of PINK1/Parkin in the formic acid‐induced autophagy of PC12 cells	4
Adverse effects of an aldosterone synthase (CYP11B2) inhibitor, fadrozole (FAD286), on inflamed rat colon	4
Behavioural interaction of pyrazoloquinolinone positive allosteric modulators at α6GABAA receptors and diazepam in rats: Anti‐diazepam‐induced ataxia action as a structure‐dependent feature	4
Comparing different postoperative sedation strategies for patients in the intensive care unit after cardiac surgery: A systematic review of randomized controlled trials and network meta‐analysis	4
The role of peroxisome proliferator‐activated receptors in the regulation of bile acid metabolism	4
3D human liver spheroids for translational pharmacology and toxicology	4

Issue Information	4
Direct oral anticoagulant concentrations and adherence in stroke patients	4
Optimal dosing of gliclazide—A model‐based approach	4
Bruceine A Inhibits Cell Proliferation by Targeting the USP13/PARP1 Signalling Pathway in Multiple Myeloma	4
The role of decision tree and machine learning models for outcome prediction of bupropion exposure: A nationwide analysis of more than 14 000 patients in the United States	4
Gastroprotective effect of sumatriptan against indomethacin‐, stress‐ and ethanol‐induced gastric damage in male rats: Possible modulatory role of 5‐hydroxytryptamine 1B/1D receptors and pro‐inflammat	4
Investigating the P53‐dependent anti‐cancer effect of ibutamoren in human cancer cell lines	4
DPYD genotyping and dihydropyrimidine dehydrogenase (DPD) phenotyping in clinical oncology. A clinically focused minireview	4
Structure–activity relationship of GPR15L peptide analogues and investigation of their interaction with the GPR15 receptor	4
The protective effect of solidagenone from Solidago chilensis Meyen in a mouse model of airway inflammation	4
Should high‐dose N‐acetylcysteine be given in cases of massive paracetamol overdoses: A narrative review	4
Ribavirin inhibits cell proliferation and metastasis and prolongs survival in soft tissue sarcomas by downregulating both protein arginine methyltransferases 1 and 5	4
Limited sampling approach for model‐informed precision dosing of daptomycin to rapidly achieving the target area under the concentration‐time curve: A simulation study	4
Vancomycin audit in the paediatric population: Patterns of use and appropriateness of therapeutic drug monitoring	4
The effects of cannabidiol against Methotrexate‐induced lung damage	4
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α‐Lipoic acid up‐regulates gene expression but reduces protein levels of fibroblast growth factor 21 in HepG2 cells	4
Phase I clinical trial evaluating the safety, tolerance, pharmacokinetics and pharmacodynamics of HSK21542 injection in healthy volunteers	4
Eugenol delays the onset of ouabain‐induced ventricular cardiac arrhythmias in guinea pigs	4