Basic & Clinical Pharmacology & Toxicology

Papers
(The TQCC of Basic & Clinical Pharmacology & Toxicology is 6. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-08-01 to 2026-08-01.)
ArticleCitations
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Patients' Attitudes Towards Deprescribing Differ Across Specific Cardiovascular and Diabetes Medication: A Survey Study Assessing Within‐Patient Differences45
Register‐based study on prescription renewal without the prescriber meeting the patient43
Antioxidant, Antiinflammatory and Antiapoptotic Effects of Lycopene in Rats With Vancomycin‐Induced Nephrotoxicity36
Copper fabric improves the metabolic profile of obese mice: Potential role of the gut microbiota31
Matrix metalloproteinases are associated with severity of disease among COVID‐19 patients: A possible pharmacological target31
How does deprescribing (not) reduce mortality? A review of a meta‐analysis in community‐dwelling older adults casts uncertainty over claimed benefits30
Barriers and Facilitators to Pharmacist‐Led Deprescribing of Antihypertensives in Long‐Term Care: A Survey‐Based Study30
The Pharmacokinetics, Pharmacological Mechanisms and Clinical Application of Zhenwu Decoction29
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Nintedanib Lacks Efficacy in a Spirometry‐Confirmed and Bleomycin‐Induced Mouse Model of Idiopathic Pulmonary Fibrosis25
Patients' Attitudes Towards Deprescribing and Associations With Patient‐Related Factors Across Two Hospital Settings25
Role of Inflammatory and Proresolving Mediators in Endothelial Dysfunction24
Artesunate alleviates intracerebral haemorrhage secondary injury by inducing ferroptosis in M1‐polarized microglia and suppressing inflammation through AMPK/mTORC1/GPX4 pathway24
Electrochemical Point‐of‐Care Test for Assessing Serum Paracetamol Concentration: Comparison With Traditional Methods and Detection of Concomitant Drugs23
The Imperative of Involving Nurses When Reviewing Psychiatric Medication: a Qualitative Study of Implementing Physician‐Led Medication Reviews for Psychiatric Outpatients With Diabetes23
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Association Between Urinary Heavy Metals and Developmental Disorders in Children Aged 6–15 Years: A Study Based on the NHANES Database22
A characterization of patients with low soluble urokinase plasminogen activator receptor who died within 90 days of hospital discharge21
Vitamin D and SARS‐CoV‐220
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Cytotoxicity, genotoxicity and mutagenicity of mixed ternary mononuclear Mg complex based on valproic acid with 1,10‐phenanthroline in Saccharomyces cerevisiae and V79 cells20
Impact of Tacrolimus Intra‐Patient Variability on Toxicity Development Among Lung Transplant Recipients19
Sapanisertib attenuates pulmonary fibrosis by modulating Wnt5a/mTOR signalling19
Preclinical safety and biodistribution assessment of Ad‐KCNH2‐G628S administered via atrial painting in New Zealand white rabbits19
Drug metabolism and drug transport of the 100 most prescribed oral drugs19
Medication use among the oldest old in the Faroe Islands—A national cross‐sectional study18
Methadone pharmacokinetics in opioid agonist treatment: Influencing factors and clinical implications18
The alleviatory effects of koumine on MSU‐induced gouty arthritis via the TLR4/NF‐κB/NLRP3 pathway18
Pregnane X receptor activation induces liver enlargement and regeneration and simultaneously promotes the metabolic activity of CYP3A1/2 and CYP2C6/11 in rats18
Decreased blood pressure with acute administration of quercetin in L‐NAME‐induced hypertensive rats17
Sp1‐Mettl14 Feedback Loop Promotes Ferroptosis in Mycobacterium tuberculosis –Infected Microglia b17
The Incidence of Benzodiazepine and Benzodiazepine‐Related Drug Use in People With and Without Parkinson's Disease—A Nationwide Cohort Study17
The Patient Typology about deprescribing and medication‐related decisions: A quantitative exploration16
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Prescribing and deprescribing trends in schizophrenia: An overview of inpatients in Belgium and in the Canadian province of Québec15
Chemokines in Alzheimer's Disease: Early Defence, Late Damage and the Impact of Sex and Infection15
Increased Mitochondrial Superoxide Level Is Partially Associated With Vemurafenib‐Induced Renal Tubular Toxicity15
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Liquiritigenin‐Rich Hydroalcoholic Extract of Brazilian Red Propolis Reduces Dyskinesia Induced by 3,4‐ Dihydroxyphenylalanine in Hemiparkinsonian Rats14
Leaky lessons learned: Efflux prone dopamine transporter variant reveals sex and circuit specific contributions of D2 receptor signalling to neuropsychiatric disease14
Significant Antispastic Effect of Combined Fasudil and Isosorbide Dinitrate on Internal Mammary Artery in Coronary Artery Bypass Grafting14
Drugs targeting APOE4 that regulate beta‐amyloid aggregation in the brain: Therapeutic potential for Alzheimer's disease14
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In Vitro Antitrypanosomal and Antibacterial Activity of Aqueous, Hydroethanolic and Ethanolic Extracts of Rumex obtusifolius 14
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Fluvoxamine Inhibited NLRP3 and NF‐κB Inflammatory Pathways and Maintained Genital Functions by Ameliorating CD‐MPR, KISS‐1, AQP4 and Claudin‐1 Expressions13
Copper: From enigma to therapeutic target for neurological disorder13
New Monitoring Recommendations for Digoxin During the Last Decade Are Associated With Decreased Serum Digoxin Concentrations in Patient Samples13
Effects of organic chemicals from diesel exhaust particles on adipocytes differentiated from human mesenchymal stem cells13
Maternal Dyslipidaemia Aggravates Offspring Metabolic Dysfunction–Associated Steatotic Liver Disease13
Metabolism studies of 4′Cl‐CUMYL‐PINACA, 4′F‐CUMYL‐5F‐PINACA and 4′F‐CUMYL‐5F‐PICA using human hepatocytes and LC‐QTOF‐MS analysis13
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Bergaptol Alleviates Oxidative Stress and Inflammation in Intracerebral Haemorrhage Mice via JAK2/STAT3 and NF‐κB Pathways, Improving Neurological Function13
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Further perspectives on statin use in patients with chronic kidney disease12
CYP2D6 Copy Number Variations Identified by KASP PCR12
ChatGPT: First glance from a perspective of clinical pharmacology12
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Review of the Delay of Chronic Kidney Disease Progression by Wuling San on Improving Renal Fibrosis12
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Hyperfiltration and Metabolism Before and After a Low‐Calorie, Pre‐Gastric Bypass Surgery Diet: Significance for Concentrations of Hydrophilic and Lipophilic Drugs12
S1PR3 Inactivation Aggravates Cerebrovascular Endothelial Cell Permeability Mediated by cPLA 2 and STAT3 Phosphorylation Under Oxidative Stress12
The Role of Hydroxychloroquine in the Management of Rheumatic Disorders: A Comprehensive Review11
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Deprescribing in primary care without deterioration of health‐related outcomes: A real‐life, quality improvement project11
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Exosomal lncRNA HOTAIR promotes osteoclast differentiation by targeting TGF‐β/PTHrP/RANKL pathway11
BCPT 2024 Prizes and Awards11
Development of an Artificial Intelligence Powered Medication Risk Score Calculator Application11
The state of deprescribing research: How did we get here?11
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The stimulant cathine from Khat causes tachycardia indirectly in the rat11
Advancing deprescribing: Learnings from the first international conference on deprescribing11
Assessment of Rivaroxaban Plasma Concentration Using Chromogenic Anti‐Xa Assays and UHPLC–MS/MS in Chinese Patients With Atrial Fibrillation11
Antagonism of Kinin Receptors B1 and B2 Attenuates Folic Acid‐Induced Tubulointerstitial Fibrosis in Mice10
BCPT 2025 Prizes and Awards10
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Persistence to statin treatment: A cohort study in Lithuania10
Ameliorative Role of β‐Caryophyllene on Antioxidant Biomarkers in a Paroxetine‐Induced Model of Male Sexual Dysfunction10
Role of bradykinin and prostaglandin EP4 receptors in regulating TRPV1 channel sensitization in rat dorsal root ganglion neurons10
A Scoping Review of Dehydrozingerone in Preclinical Pharmacology: Activities, Dose Ranges and Toxicity10
Inappropriate polypharmacy management versus deprescribing: A review on their relationship10
Correction to Involvement of H 2 S, NO and BDNF‐TrkB signalling pathway in the protective effects of simvastatin against pentylenetetrazole‐induced k10
Medication Burden: Beyond Counts to Recognize Polypharmacy as an Inherent Part of Living With Chronic Kidney Disease10
Effects of GLP‐1 Receptor Agonists in Alcohol Use Disorder10
Optimizing autophagy modulation for enhanced TRAIL‐mediated therapy: Unveiling the superiority of late‐stage inhibition over early‐stage inhibition to overcome therapy resistance in cancer10
In vitro effect of hyoscine‐N‐butyl bromide and diclofenac sodium in human tuba uterina10
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Efficacy of weekly versus daily cholecalciferol for repleting serum vitamin D (25(OH)D) deficiency: A systematic review and meta‐analysis of randomized controlled trials9
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Four weeks SGLT2 inhibition improves beta cell function and glucose tolerance without affecting muscle free fatty acid or glucose uptake in subjects with type 2 diabetes9
Modulation of Respiratory Diseases by the Endocannabinoid System: A Therapeutic Perspective9
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‘This Is My Decision’: A Qualitative Study of Individuals' Perspectives on Use of Semaglutide for Weight Loss9
Trends in Antithrombotic Therapy Initiation Among Patients With Stroke Pre‐ and Post–COVID‐19 in Sweden—An Interrupted Time Series Study9
Questions in Healthcare Specifically Related to the Discipline of Pharmacy: A Descriptive Analysis of Queries to Drug Information Centres in Sweden9
Making it happen: Development of an interprofessional deprescribing education programme9
Curcumin Alleviates Myocardial Ischaemia–Reperfusion Injury by Inhibiting NLRP3 Inflammasome Activation and Pyroptosis via the Nrf2/HO‐1 Pathway: An Integrated Network Pharmacology and Experimental St9
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The Molecular and Clinical Impact of Atorvastatin Exposure on Paclitaxel Neurotoxicity in Sensory Neurons and Cancer Patients9
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Levothyroxine Treatment During Pregnancy: A Metabolomics Study9
Dose safety and pharmacodynamics of subcutaneous bupivacaine in a novel extended‐release microparticle formulation: A phase 1, dose‐ascending study in male volunteers9
Special Collection: Mechanisms of Vasodilatation Endothelium‐Dependent Hyperpolarization (MOVD/EDH2024)8
From Hospital to Home: Patient Experiences With Medication Counselling for Colorectal Cancer8
Gadoteric Acid Induces Dose‐Dependent DNA Damage and Enzyme Binding in Fibroblast Cells8
Paroxetine alleviates ulcerative colitis in mice via restoring intestinal microbiota homeostasis and metabolism8
Berberine regulates pulmonary inflammatory microenvironment and decreases collagen deposition in response to bleomycin‐induced pulmonary fibrosis in mice8
Evidence for a Two‐Step Model for Activation of GPR25 by the Chemoattractant CXCL178
Effect of stearyl alcohol on imiquimod‐induced psoriasis‐like skin inflammation in mice8
Dementia and neurodegenerative diseases: What is known and what is promising at the cellular and molecular level8
Technology‐Driven Decision Support for Opioid Tapering: A Scoping Review8
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Development of a Deprescribing Intervention for Proton Pump Inhibitors in Primary Care: A Co‐Design Approach With General Practitioners and Patients8
Gentiopicroside Attenuated Dopaminergic Neurodegeneration via Inhibiting Neuroinflammatory Responses and Ferroptosis in Experimental Models of Parkinson's Disease8
Facilitating the Implementation of Physician‐Led Medication Reviews for Patients With Severe Mental Disorder and Diabetes: A Cost‐Minimization Analysis8
Effects of rifampicin on porphyrin metabolism in healthy volunteers8
Welcome to Basic & Clinical Pharmacology & Toxicology 20248
Toxicity and therapy outcome associations in LIG3, SLCO1B3, ABCB1, OPRM1 and GSTP1 in high‐grade serous ovarian cancer7
Traditional Chinese Medicine for Inhibiting Ferroptosis in Ischemic‐Related Diseases7
Growth differentiation factor 15 is dispensable for acetaminophen‐induced liver injury in mice7
The Effects of Drugs on CYP3A Enzyme Activity and Protein Expression Through Ubiquitination Modification Regulation7
Correction to ‘β‐LAPachone Ameliorates Doxorubicin‐Induced Cardiotoxicity via Regulating Autophagy and Nrf2 Signalling Pathways in Mice’7
Learnings From a Knowledge Mobilization Strategy to Integrate a Deprescribing Educational Curriculum Into Health Professional Programmes7
Deaths caused by medication in persons not using illicit narcotic drugs: An autopsy study from Western Denmark7
The Pathobiology of Cerebrovascular Lesions in CADASIL Small Vessel Disease7
The effectiveness and safety of botulinum toxin injections for managing motor disorders of patients with Parkinson's disease: A meta‐analysis of randomized controlled trials7
Application of Artificial Intelligence in the Development of Traditional Chinese Medicine7
Exploratory pharmacovigilance with machine learning in big patient data: A focused scoping review7
High Throughput Pharmacovigilance Screening for Roflumilast Adverse Effects in Real‐World Settings: A Sequence Symmetry Analysis7
Foetal Exposure to Phthalates and Endocrine Effects on the Leydig Cell7
Making Transparency and Reproducibility a Hallmark of Nordic Real‐World Evidence7
Therapeutic benefit of melatonin in 5‐fluorouracil‐induced renal and hepatic injury7
Ten deprescribing articles you should know about: A guide for newcomers to the field7
Prescribing Patterns in Fatal Intoxications Involving Zopiclone and Alprazolam: An Observational Register‐Based Study7
Plasma NGAL, suPAR, KIM‐1 and GDF‐15 for Improving Glomerular Filtration Rate Estimation in Older Hospitalized Patients7
Healthcare Providers' Perspectives on Antidepressant Discontinuation: A Focus Group Study7
Study of the mechanism underlying the role of PINK1/Parkin in the formic acid‐induced autophagy of PC12 cells6
Multi‐Target Renal Protection of Wine‐Processed Polygonatum sibiricum Against Cisplatin‐Induced Nephrotoxicity: Integrated Phytochemistry, Network Pharmacology and Experimental Valid6
Initiation of Anticoagulants During the COVID‐19 Pandemic in Sweden: An Interrupted Time Series Analysis6
Association Between Levels of the Acute Phase Proteins Alpha‐1‐Acid Glycoprotein and C‐Reactive Protein and Serum Concentrations of Clozapine: A Study of 1106 Therapeutic Drug Monitoring Samples6
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Limited sampling approach for model‐informed precision dosing of daptomycin to rapidly achieving the target area under the concentration‐time curve: A simulation study6
Insights Into Gut Barrier Dysfunction and Metabolic Alterations in Mycophenolate‐Induced Enteropathy6
Categorization of deprescribing communication tools: A scoping review6
Understanding Medication Errors Through Patient Complaints in a Danish University Hospital6
Neuroprotective Effects of Esketamine in Central Nervous System Disorders: Mechanisms and Cellular Targets6
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The role of decision tree and machine learning models for outcome prediction of bupropion exposure: A nationwide analysis of more than 14 000 patients in the United States6
Biomarkers of Parkinson's disease in perspective of early diagnosis and translation of neurotrophic therapies6
Phase I clinical trial evaluating the safety, tolerance, pharmacokinetics and pharmacodynamics of HSK21542 injection in healthy volunteers6
Should high‐dose N‐acetylcysteine be given in cases of massive paracetamol overdoses: A narrative review6
Optimal dosing of gliclazide—A model‐based approach6
Investigating the P53‐dependent anti‐cancer effect of ibutamoren in human cancer cell lines6
Triptolide alleviates collagen‐induced arthritis in mice by modulating Treg/Th17 imbalance through the JAK/PTEN‐STAT3 pathway6
Eugenol Alleviates Cerebral Ischemia–Reperfusion Injury in Mice by Promoting the Phagocytosis of Microglia via Up‐Regulating Tripartite Motif Protein 596
Association between patient attitudes towards deprescribing and subsequent prescription changes6
Association Between Furosemide and Risk of Parkinson's Disease in a Nested Case–Control Study6
Emergency Department Visits due to Medication Overdose in a Finnish University Hospital6
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Vancomycin audit in the paediatric population: Patterns of use and appropriateness of therapeutic drug monitoring6
Gastroprotective effect of sumatriptan against indomethacin‐, stress‐ and ethanol‐induced gastric damage in male rats: Possible modulatory role of 5‐hydroxytryptamine 1B/1D receptors and pro‐inflammat6
Behavioural interaction of pyrazoloquinolinone positive allosteric modulators at α6GABAA receptors and diazepam in rats: Anti‐diazepam‐induced ataxia action as a structure‐dependent feature6
CYP3A4*22 and bleeding risk in ticagrelor users6
A review on the new age methodologies for early detection of Alzheimer's and Parkinson's disease6
LW‐AFC Protects Against Neurological and Neuropsychiatric Effects of SARS‐CoV‐2 Spike Protein in Mice6
Bruceine A Inhibits Cell Proliferation by Targeting the USP13/PARP1 Signalling Pathway in Multiple Myeloma6
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