Basic & Clinical Pharmacology & Toxicology

Article	Citations
Issue Information	301
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Barriers and Facilitators to Pharmacist‐Led Deprescribing of Antihypertensives in Long‐Term Care: A Survey‐Based Study	71
Patients' Attitudes Towards Deprescribing Differ Across Specific Cardiovascular and Diabetes Medication: A Survey Study Assessing Within‐Patient Differences	70
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Matrix metalloproteinases are associated with severity of disease among COVID‐19 patients: A possible pharmacological target	36
Role of Inflammatory and Proresolving Mediators in Endothelial Dysfunction	31
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Copper fabric improves the metabolic profile of obese mice: Potential role of the gut microbiota	27
Lithium and the risk of chronic kidney disease: A population‐based case–control study	26
Register‐based study on prescription renewal without the prescriber meeting the patient	26
A two‐decade review of butane toxicity as a substance of abuse	24
Artesunate alleviates intracerebral haemorrhage secondary injury by inducing ferroptosis in M1‐polarized microglia and suppressing inflammation through AMPK/mTORC1/GPX4 pathway	23
Nintedanib Lacks Efficacy in a Spirometry‐Confirmed and Bleomycin‐Induced Mouse Model of Idiopathic Pulmonary Fibrosis	22
Antioxidant, Antiinflammatory and Antiapoptotic Effects of Lycopene in Rats With Vancomycin‐Induced Nephrotoxicity	21
Patients' Attitudes Towards Deprescribing and Associations With Patient‐Related Factors Across Two Hospital Settings	21
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The Pharmacokinetics, Pharmacological Mechanisms and Clinical Application of Zhenwu Decoction	20
How does deprescribing (not) reduce mortality? A review of a meta‐analysis in community‐dwelling older adults casts uncertainty over claimed benefits	20
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Electrochemical Point‐of‐Care Test for Assessing Serum Paracetamol Concentration: Comparison With Traditional Methods and Detection of Concomitant Drugs	20
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A characterization of patients with low soluble urokinase plasminogen activator receptor who died within 90 days of hospital discharge	19
The alleviatory effects of koumine on MSU‐induced gouty arthritis via the TLR4/NF‐κB/NLRP3 pathway	19

Cytotoxicity, genotoxicity and mutagenicity of mixed ternary mononuclear Mg complex based on valproic acid with 1,10‐phenanthroline in Saccharomyces cerevisiae and V79 cells	19
Pregnane X receptor activation induces liver enlargement and regeneration and simultaneously promotes the metabolic activity of CYP3A1/2 and CYP2C6/11 in rats	19
Decreased blood pressure with acute administration of quercetin in L‐NAME‐induced hypertensive rats	18
Vitamin D and SARS‐CoV‐2	17
Preclinical safety and biodistribution assessment of Ad‐KCNH2‐G628S administered via atrial painting in New Zealand white rabbits	17
Methadone pharmacokinetics in opioid agonist treatment: Influencing factors and clinical implications	17
Medication use among the oldest old in the Faroe Islands—A national cross‐sectional study	17
The Patient Typology about deprescribing and medication‐related decisions: A quantitative exploration	16
Drug metabolism and drug transport of the 100 most prescribed oral drugs	16
Impact of Tacrolimus Intra‐Patient Variability on Toxicity Development Among Lung Transplant Recipients	15
The Incidence of Benzodiazepine and Benzodiazepine‐Related Drug Use in People With and Without Parkinson's Disease—A Nationwide Cohort Study	15
Sapanisertib attenuates pulmonary fibrosis by modulating Wnt5a/mTOR signalling	15
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Sp1‐Mettl14 Feedback Loop Promotes Ferroptosis in Mycobacterium tuberculosis –Infected Microglia b	15
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Increased Mitochondrial Superoxide Level Is Partially Associated With Vemurafenib‐Induced Renal Tubular Toxicity	14
Drugs targeting APOE4 that regulate beta‐amyloid aggregation in the brain: Therapeutic potential for Alzheimer's disease	14
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New Monitoring Recommendations for Digoxin During the Last Decade Are Associated With Decreased Serum Digoxin Concentrations in Patient Samples	14
Prescribing and deprescribing trends in schizophrenia: An overview of inpatients in Belgium and in the Canadian province of Québec	14
Liquiritigenin‐Rich Hydroalcoholic Extract of Brazilian Red Propolis Reduces Dyskinesia Induced by 3,4‐ Dihydroxyphenylalanine in Hemiparkinsonian Rats	14
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Effects of organic chemicals from diesel exhaust particles on adipocytes differentiated from human mesenchymal stem cells	13
Bergaptol Alleviates Oxidative Stress and Inflammation in Intracerebral Haemorrhage Mice via JAK2/STAT3 and NF‐κB Pathways, Improving Neurological Function	13
Metabolism studies of 4′Cl‐CUMYL‐PINACA, 4′F‐CUMYL‐5F‐PINACA and 4′F‐CUMYL‐5F‐PICA using human hepatocytes and LC‐QTOF‐MS analysis	13
Significant Antispastic Effect of Combined Fasudil and Isosorbide Dinitrate on Internal Mammary Artery in Coronary Artery Bypass Grafting	13
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In Vitro Antitrypanosomal and Antibacterial Activity of Aqueous, Hydroethanolic and Ethanolic Extracts of Rumex obtusifolius	12
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Hyperfiltration and Metabolism Before and After a Low‐Calorie, Pre‐Gastric Bypass Surgery Diet: Significance for Concentrations of Hydrophilic and Lipophilic Drugs	12
Fluvoxamine Inhibited NLRP3 and NF‐κB Inflammatory Pathways and Maintained Genital Functions by Ameliorating CD‐MPR, KISS‐1, AQP4 and Claudin‐1 Expressions	12
Copper: From enigma to therapeutic target for neurological disorder	12
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Exosomal lncRNA HOTAIR promotes osteoclast differentiation by targeting TGF‐β/PTHrP/RANKL pathway	12
Leaky lessons learned: Efflux prone dopamine transporter variant reveals sex and circuit specific contributions of D2 receptor signalling to neuropsychiatric disease	12
Further perspectives on statin use in patients with chronic kidney disease	12
CYP2D6 Copy Number Variations Identified by KASP PCR	12
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The stimulant cathine from Khat causes tachycardia indirectly in the rat	11
ChatGPT: First glance from a perspective of clinical pharmacology	11
The Role of Hydroxychloroquine in the Management of Rheumatic Disorders: A Comprehensive Review	11
BCPT 2024 Prizes and Awards	11
S1PR3 Inactivation Aggravates Cerebrovascular Endothelial Cell Permeability Mediated by cPLA 2 and STAT3 Phosphorylation Under Oxidative Stress	11
Review of the Delay of Chronic Kidney Disease Progression by Wuling San on Improving Renal Fibrosis	11
Effect of dexmedetomidine on oxytocin‐induced uterine contraction during optimal caesarean section anaesthesia	11
Development of an Artificial Intelligence Powered Medication Risk Score Calculator Application	10
Inappropriate polypharmacy management versus deprescribing: A review on their relationship	10
The state of deprescribing research: How did we get here?	10

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First‐in‐human study with ACT‐1014‐6470, a novel oral complement factor 5a receptor 1 (C5aR1) antagonist, supported by pharmacokinetic predictions from animals to patients	10
Role of bradykinin and prostaglandin EP4 receptors in regulating TRPV1 channel sensitization in rat dorsal root ganglion neurons	10
BCPT 2025 Prizes and Awards	10
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Deprescribing in primary care without deterioration of health‐related outcomes: A real‐life, quality improvement project	10
Assessment of Rivaroxaban Plasma Concentration Using Chromogenic Anti‐Xa Assays and UHPLC–MS/MS in Chinese Patients With Atrial Fibrillation	10
Advancing deprescribing: Learnings from the first international conference on deprescribing	9
Effects of GLP‐1 Receptor Agonists in Alcohol Use Disorder	9
Trends in Antithrombotic Therapy Initiation Among Patients With Stroke Pre‐ and Post–COVID‐19 in Sweden—An Interrupted Time Series Study	9
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Ameliorative Role of β‐Caryophyllene on Antioxidant Biomarkers in a Paroxetine‐Induced Model of Male Sexual Dysfunction	9
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Antagonism of Kinin Receptors B1 and B2 Attenuates Folic Acid‐Induced Tubulointerstitial Fibrosis in Mice	9
The Molecular and Clinical Impact of Atorvastatin Exposure on Paclitaxel Neurotoxicity in Sensory Neurons and Cancer Patients	9
Optimizing autophagy modulation for enhanced TRAIL‐mediated therapy: Unveiling the superiority of late‐stage inhibition over early‐stage inhibition to overcome therapy resistance in cancer	9
Questions in Healthcare Specifically Related to the Discipline of Pharmacy: A Descriptive Analysis of Queries to Drug Information Centres in Sweden	9
In vitro effect of hyoscine‐N‐butyl bromide and diclofenac sodium in human tuba uterina	9
Persistence to statin treatment: A cohort study in Lithuania	9
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Paroxetine alleviates ulcerative colitis in mice via restoring intestinal microbiota homeostasis and metabolism	8
Making it happen: Development of an interprofessional deprescribing education programme	8
Dose safety and pharmacodynamics of subcutaneous bupivacaine in a novel extended‐release microparticle formulation: A phase 1, dose‐ascending study in male volunteers	8
‘This Is My Decision’: A Qualitative Study of Individuals' Perspectives on Use of Semaglutide for Weight Loss	8
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Special Collection: Mechanisms of Vasodilatation Endothelium‐Dependent Hyperpolarization (MOVD/EDH2024)	8
Curcumin Alleviates Myocardial Ischaemia–Reperfusion Injury by Inhibiting NLRP3 Inflammasome Activation and Pyroptosis via the Nrf2/HO‐1 Pathway: An Integrated Network Pharmacology and Experimental St	8
Somatostatin receptor ligands suppressed proliferation and lipogenesis in 3T3‐L1 preadipocytes	8
Four weeks SGLT2 inhibition improves beta cell function and glucose tolerance without affecting muscle free fatty acid or glucose uptake in subjects with type 2 diabetes	8
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Efficacy of weekly versus daily cholecalciferol for repleting serum vitamin D (25(OH)D) deficiency: A systematic review and meta‐analysis of randomized controlled trials	8
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Correction to Involvement of H 2 S, NO and BDNF‐TrkB signalling pathway in the protective effects of simvastatin against pentylenetetrazole‐induced k	8
Effect of stearyl alcohol on imiquimod‐induced psoriasis‐like skin inflammation in mice	7
Downregulation of GPR160 inhibits the progression of glioma through suppressing epithelial to mesenchymal transition (EMT) biomarkers	7
Facilitating the Implementation of Physician‐Led Medication Reviews for Patients With Severe Mental Disorder and Diabetes: A Cost‐Minimization Analysis	7
Studies on the mode of action of synthetic diindolylmethane derivatives against triple negative breast cancer cells	7
Welcome to Basic & Clinical Pharmacology & Toxicology 2024	7
Correction to ‘β‐LAPachone Ameliorates Doxorubicin‐Induced Cardiotoxicity via Regulating Autophagy and Nrf2 Signalling Pathways in Mice’	7
The effectiveness and safety of botulinum toxin injections for managing motor disorders of patients with Parkinson's disease: A meta‐analysis of randomized controlled trials	7
Ten deprescribing articles you should know about: A guide for newcomers to the field	7
Gentiopicroside Attenuated Dopaminergic Neurodegeneration via Inhibiting Neuroinflammatory Responses and Ferroptosis in Experimental Models of Parkinson's Disease	7
Effects of rifampicin on porphyrin metabolism in healthy volunteers	7
From Hospital to Home: Patient Experiences With Medication Counselling for Colorectal Cancer	7
Dementia and neurodegenerative diseases: What is known and what is promising at the cellular and molecular level	7
Association between patient attitudes towards deprescribing and subsequent prescription changes	7
The Effects of Drugs on CYP3A Enzyme Activity and Protein Expression Through Ubiquitination Modification Regulation	7
A review on the new age methodologies for early detection of Alzheimer's and Parkinson's disease	7
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Development of a Deprescribing Intervention for Proton Pump Inhibitors in Primary Care: A Co‐Design Approach With General Practitioners and Patients	7
Gadoteric Acid Induces Dose‐Dependent DNA Damage and Enzyme Binding in Fibroblast Cells	7
Berberine regulates pulmonary inflammatory microenvironment and decreases collagen deposition in response to bleomycin‐induced pulmonary fibrosis in mice	7
Therapeutic benefit of melatonin in 5‐fluorouracil‐induced renal and hepatic injury	7
Exploratory pharmacovigilance with machine learning in big patient data: A focused scoping review	7
Pharmacokinetics of free and total mycophenolic acid in paediatric and adult renal transplant recipients: Exploratory analysis of the effects of clinical factors and gene variants	7
Growth differentiation factor 15 is dispensable for acetaminophen‐induced liver injury in mice	7
Emergency Department Visits due to Medication Overdose in a Finnish University Hospital	6
Triptolide alleviates collagen‐induced arthritis in mice by modulating Treg/Th17 imbalance through the JAK/PTEN‐STAT3 pathway	6
Foetal Exposure to Phthalates and Endocrine Effects on the Leydig Cell	6
Toxicity and therapy outcome associations in LIG3, SLCO1B3, ABCB1, OPRM1 and GSTP1 in high‐grade serous ovarian cancer	6
The Pathobiology of Cerebrovascular Lesions in CADASIL Small Vessel Disease	6
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LW‐AFC Protects Against Neurological and Neuropsychiatric Effects of SARS‐CoV‐2 Spike Protein in Mice	6
Eugenol Alleviates Cerebral Ischemia–Reperfusion Injury in Mice by Promoting the Phagocytosis of Microglia via Up‐Regulating Tripartite Motif Protein 59	6
Biomarkers of Parkinson's disease in perspective of early diagnosis and translation of neurotrophic therapies	6
Insights Into Gut Barrier Dysfunction and Metabolic Alterations in Mycophenolate‐Induced Enteropathy	6
Application of Artificial Intelligence in the Development of Traditional Chinese Medicine	6
Deaths caused by medication in persons not using illicit narcotic drugs: An autopsy study from Western Denmark	6
High Throughput Pharmacovigilance Screening for Roflumilast Adverse Effects in Real‐World Settings: A Sequence Symmetry Analysis	6
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Categorization of deprescribing communication tools: A scoping review	6
Multi‐Target Renal Protection of Wine‐Processed Polygonatum sibiricum Against Cisplatin‐Induced Nephrotoxicity: Integrated Phytochemistry, Network Pharmacology and Experimental Valid	6
Bruceine A Inhibits Cell Proliferation by Targeting the USP13/PARP1 Signalling Pathway in Multiple Myeloma	6
The role of decision tree and machine learning models for outcome prediction of bupropion exposure: A nationwide analysis of more than 14 000 patients in the United States	6
Plasma NGAL, suPAR, KIM‐1 and GDF‐15 for Improving Glomerular Filtration Rate Estimation in Older Hospitalized Patients	6
Healthcare Providers' Perspectives on Antidepressant Discontinuation: A Focus Group Study	6
Traditional Chinese Medicine for Inhibiting Ferroptosis in Ischemic‐Related Diseases	6

Learnings From a Knowledge Mobilization Strategy to Integrate a Deprescribing Educational Curriculum Into Health Professional Programmes	6
Study of the mechanism underlying the role of PINK1/Parkin in the formic acid‐induced autophagy of PC12 cells	6
Neuroprotective Effects of Esketamine in Central Nervous System Disorders: Mechanisms and Cellular Targets	6
α‐Lipoic acid up‐regulates gene expression but reduces protein levels of fibroblast growth factor 21 in HepG2 cells	5
Effect of Acute Exposure of Swiss Mice to Chlorogenic Acid	5
Ribavirin inhibits cell proliferation and metastasis and prolongs survival in soft tissue sarcomas by downregulating both protein arginine methyltransferases 1 and 5	5
Cyclopeptide mushroom poisoning: A retrospective series of 204 patients	5
Disease‐modifying therapies in multiple sclerosis: A focused review of rituximab	5
Carnosol attenuated atrophy of C2C12 myotubes induced by tumour‐derived exosomal miR‐183‐5p through inhibiting Smad3 pathway activation and keeping mitochondrial respiration	5
The role of peroxisome proliferator‐activated receptors in the regulation of bile acid metabolism	5
CYP3A4*22 and bleeding risk in ticagrelor users	5
Comparing different postoperative sedation strategies for patients in the intensive care unit after cardiac surgery: A systematic review of randomized controlled trials and network meta‐analysis	5
Adverse effects of an aldosterone synthase (CYP11B2) inhibitor, fadrozole (FAD286), on inflamed rat colon	5
Limited sampling approach for model‐informed precision dosing of daptomycin to rapidly achieving the target area under the concentration‐time curve: A simulation study	5
Investigating the P53‐dependent anti‐cancer effect of ibutamoren in human cancer cell lines	5
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The effects of cannabidiol against Methotrexate‐induced lung damage	5
Behavioural interaction of pyrazoloquinolinone positive allosteric modulators at α6GABAA receptors and diazepam in rats: Anti‐diazepam‐induced ataxia action as a structure‐dependent feature	5
Retraction	5
Should high‐dose N‐acetylcysteine be given in cases of massive paracetamol overdoses: A narrative review	5
Coumarins and Their Derivatives in Animal Models of Asthma: A Systematic Review	5
Long‐Term Safety and Efficacy of AAV9 Vectors Expressing Human SMN1 Gene: A Preclinical Study	5
Gastroprotective effect of sumatriptan against indomethacin‐, stress‐ and ethanol‐induced gastric damage in male rats: Possible modulatory role of 5‐hydroxytryptamine 1B/1D receptors and pro‐inflammat	5
Structure–activity relationship of GPR15L peptide analogues and investigation of their interaction with the GPR15 receptor	5
Phase I clinical trial evaluating the safety, tolerance, pharmacokinetics and pharmacodynamics of HSK21542 injection in healthy volunteers	5
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Blood Pressure–Lowering Effects of Aldosterone Synthase Inhibitors—A Systematic Review	5
Models of Endocrine‐Disrupting Effects: Human Placental Steroidogenesis	5
Parental cigarette smoking before and during pregnancy in a cohort of 21 472 pregnancies	5
Vancomycin audit in the paediatric population: Patterns of use and appropriateness of therapeutic drug monitoring	5
Review of clinical pharmacokinetics and pharmacodynamics of clonidine as an adjunct to opioids in palliative care	5
Initiation of Anticoagulants During the COVID‐19 Pandemic in Sweden: An Interrupted Time Series Analysis	5
DPYD genotyping and dihydropyrimidine dehydrogenase (DPD) phenotyping in clinical oncology. A clinically focused minireview	5
Eugenol delays the onset of ouabain‐induced ventricular cardiac arrhythmias in guinea pigs	5
Direct oral anticoagulant concentrations and adherence in stroke patients	5
Dimetindene—Is the minimum toxic dose for children too strict?	5
Optimal dosing of gliclazide—A model‐based approach	5
Association Between Levels of the Acute Phase Proteins Alpha‐1‐Acid Glycoprotein and C‐Reactive Protein and Serum Concentrations of Clozapine: A Study of 1106 Therapeutic Drug Monitoring Samples	5
Understanding Medication Errors Through Patient Complaints in a Danish University Hospital	5
The BCPT young researcher Nordic Prize 2022 goes to Associate Professor Tore Bjerregaard Stage	5
Efficacy and Safety of Clopidogrel With and Without a Proton Pump Inhibitor: A Systematic Review and Meta‐Analysis	5