Basic & Clinical Pharmacology & Toxicology

Papers
(The TQCC of Basic & Clinical Pharmacology & Toxicology is 5. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-09-01 to 2025-09-01.)
ArticleCitations
Issue Information204
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Clinical predictors of nephrotoxicity associated with teicoplanin: Meta‐analysis and meta‐regression106
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Antibiotic treatment of community‐acquired pneumonia: A questionnaire survey in Danish general practice64
Incidence in pharmacoepidemiology—Basic definitions and types of misclassification53
Copper fabric improves the metabolic profile of obese mice: Potential role of the gut microbiota43
Register‐based study on prescription renewal without the prescriber meeting the patient41
Assessment of drug–drug interactions between moxonidine and antiepileptic drugs in the maximal electroshock seizure test in mice36
Triangulation of pharmacoepidemiology and laboratory science to tackle otic quinolone safety23
Involvement of the effect of renal hypoperfusion medications on vancomycin trough concentration: A secondary analysis using a retrospective observational data23
Efficacy of fibroblast growth factor 21 in non‐alcoholic fatty liver disease in guinea pigs22
Lithium and the risk of chronic kidney disease: A population‐based case–control study22
Matrix metalloproteinases are associated with severity of disease among COVID‐19 patients: A possible pharmacological target19
Targeting of cancer cell death mechanisms by curcumin: Implications to cancer therapy19
Issue Information19
Artesunate alleviates intracerebral haemorrhage secondary injury by inducing ferroptosis in M1‐polarized microglia and suppressing inflammation through AMPK/mTORC1/GPX4 pathway18
Barriers and Facilitators to Pharmacist‐Led Deprescribing of Antihypertensives in Long‐Term Care: A Survey‐Based Study18
How does deprescribing (not) reduce mortality? A review of a meta‐analysis in community‐dwelling older adults casts uncertainty over claimed benefits17
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Role of Inflammatory and Proresolving Mediators in Endothelial Dysfunction16
A two‐decade review of butane toxicity as a substance of abuse16
Antioxidant, Antiinflammatory and Antiapoptotic Effects of Lycopene in Rats With Vancomycin‐Induced Nephrotoxicity16
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Methadone pharmacokinetics in opioid agonist treatment: Influencing factors and clinical implications15
The alleviatory effects of koumine on MSU‐induced gouty arthritis via the TLR4/NF‐κB/NLRP3 pathway15
Cytotoxicity, genotoxicity and mutagenicity of mixed ternary mononuclear Mg complex based on valproic acid with 1,10‐phenanthroline in Saccharomyces cerevisiae and V79 cells14
Possible opioid‐saving effect of cannabis‐based medicine using individual‐based data from the Norwegian Prescription Database14
Sapanisertib attenuates pulmonary fibrosis by modulating Wnt5a/mTOR signalling14
The Patient Typology about deprescribing and medication‐related decisions: A quantitative exploration14
A characterization of patients with low soluble urokinase plasminogen activator receptor who died within 90 days of hospital discharge13
Vitamin D and SARS‐CoV‐213
Preclinical safety and biodistribution assessment of Ad‐KCNH2‐G628S administered via atrial painting in New Zealand white rabbits13
Pregnane X receptor activation induces liver enlargement and regeneration and simultaneously promotes the metabolic activity of CYP3A1/2 and CYP2C6/11 in rats13
Medication use among the oldest old in the Faroe Islands—A national cross‐sectional study13
Decreased blood pressure with acute administration of quercetin in L‐NAME‐induced hypertensive rats12
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Drugs targeting APOE4 that regulate beta‐amyloid aggregation in the brain: Therapeutic potential for Alzheimer's disease12
Issue Information12
Effects of organic chemicals from diesel exhaust particles on adipocytes differentiated from human mesenchymal stem cells12
Role of cytochrome P450 2C8 genetic polymorphism and epoxygenase uncoupling in periodontal remodelling affecting orthodontic treatment12
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Drug metabolism and drug transport of the 100 most prescribed oral drugs12
Risk of kidney injury in patients on concomitant oral vancomycin and piperacillin‐tazobactam: Analysis of the pharmacovigilance database in Japan12
Translational aspects of cytochrome P450‐mediated drug–drug interactions: A case study with clopidogrel11
Liquiritigenin‐Rich Hydroalcoholic Extract of Brazilian Red Propolis Reduces Dyskinesia Induced by 3,4‐ Dihydroxyphenylalanine in Hemiparkinsonian Rats11
New Monitoring Recommendations for Digoxin During the Last Decade Are Associated With Decreased Serum Digoxin Concentrations in Patient Samples11
Issue Information11
Prescribing and deprescribing trends in schizophrenia: An overview of inpatients in Belgium and in the Canadian province of Québec11
Copper: From enigma to therapeutic target for neurological disorder11
Fluvoxamine Inhibited NLRP3 and NF‐κB Inflammatory Pathways and Maintained Genital Functions by Ameliorating CD‐MPR, KISS‐1, AQP4 and Claudin‐1 Expressions11
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Leaky lessons learned: Efflux prone dopamine transporter variant reveals sex and circuit specific contributions of D2 receptor signalling to neuropsychiatric disease11
Increased Mitochondrial Superoxide Level Is Partially Associated With Vemurafenib‐Induced Renal Tubular Toxicity11
Metabolism studies of 4′Cl‐CUMYL‐PINACA, 4′F‐CUMYL‐5F‐PINACA and 4′F‐CUMYL‐5F‐PICA using human hepatocytes and LC‐QTOF‐MS analysis11
Chronic mercury exposure induces oxidative stress in female rats by endothelial nitric oxide synthase uncoupling and cyclooxygenase‐2 activation, without affecting oestrogen receptor function11
Further perspectives on statin use in patients with chronic kidney disease10
The stimulant cathine from Khat causes tachycardia indirectly in the rat10
Effects of Zuojin Pill (Rhizoma CoptidisandFructus Evodiaepreparation) on the pharmacokinetics and side effects of venlafaxine in humans10
Potential drug‐drug interactions in acute poisonings managed in the intensive care unit: Occurrence, risk factors and relationship to patient severity on admission10
A novel flowchart to predict mortality and analyse effectiveness of routinely used pharmacological regimens in paraquat poisoning10
ChatGPT: First glance from a perspective of clinical pharmacology10
Exosomal lncRNA HOTAIR promotes osteoclast differentiation by targeting TGF‐β/PTHrP/RANKL pathway10
Review of the Delay of Chronic Kidney Disease Progression by Wuling San on Improving Renal Fibrosis9
Effects of quercetin on ovarian function and regulation of the ovarian PI3K/Akt/FoxO3a signalling pathway and oxidative stress in a rat model of cyclophosphamide‐induced premature ovarian failure9
Optimizing autophagy modulation for enhanced TRAIL‐mediated therapy: Unveiling the superiority of late‐stage inhibition over early‐stage inhibition to overcome therapy resistance in cancer9
Pro‐inflammatory cytokines/chemokines, TNF‐α, IL‐6 and MCP‐1, as biomarkers for the nephro‐ and pneumoprotective effect of silibinin after hepatic ischemia/reperfusion: Confirmation by immunohistochem9
Issue Information9
The Role of Hydroxychloroquine in the Management of Rheumatic Disorders: A Comprehensive Review9
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Effects of GLP‐1 Receptor Agonists in Alcohol Use Disorder9
Letter from the editor9
Issue Information9
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Ameliorative Role of β‐Caryophyllene on Antioxidant Biomarkers in a Paroxetine‐Induced Model of Male Sexual Dysfunction9
BCPT 2024 Prizes and Awards9
The state of deprescribing research: How did we get here?8
Correction to Involvement of H2S, NO and BDNF‐TrkB signalling pathway in the protective effects of simvastatin against pentylenetetrazole‐induced kindling and cognitive impairments in mice8
Inappropriate polypharmacy management versus deprescribing: A review on their relationship8
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Effect of dexmedetomidine on oxytocin‐induced uterine contraction during optimal caesarean section anaesthesia8
Mechanistic insights into the pathogenesis of microtubule‐targeting agent‐induced peripheral neuropathy from pharmacogenetic and functional studies8
Issue Information8
Deprescribing in primary care without deterioration of health‐related outcomes: A real‐life, quality improvement project8
First‐in‐human study with ACT‐1014‐6470, a novel oral complement factor 5a receptor 1 (C5aR1) antagonist, supported by pharmacokinetic predictions from animals to patients8
Dose safety and pharmacodynamics of subcutaneous bupivacaine in a novel extended‐release microparticle formulation: A phase 1, dose‐ascending study in male volunteers8
Advancing deprescribing: Learnings from the first international conference on deprescribing8
Issue Information8
In vitro effect of hyoscine‐N‐butyl bromide and diclofenac sodium in human tuba uterina8
Assessment of Rivaroxaban Plasma Concentration Using Chromogenic Anti‐Xa Assays and UHPLC–MS/MS in Chinese Patients With Atrial Fibrillation8
Role of bradykinin and prostaglandin EP4 receptors in regulating TRPV1 channel sensitization in rat dorsal root ganglion neurons8
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Four weeks SGLT2 inhibition improves beta cell function and glucose tolerance without affecting muscle free fatty acid or glucose uptake in subjects with type 2 diabetes8
Somatostatin receptor ligands suppressed proliferation and lipogenesis in 3T3‐L1 preadipocytes8
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Erratum7
Persistence to statin treatment: A cohort study in Lithuania7
Issue Information7
Making it happen: Development of an interprofessional deprescribing education programme7
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Efficacy of weekly versus daily cholecalciferol for repleting serum vitamin D (25(OH)D) deficiency: A systematic review and meta‐analysis of randomized controlled trials7
Disease activity and therapeutic drug monitoring of polyglutamates of methotrexate after daily or weekly administration of low‐dose methotrexate in patients recently diagnosed with rheumatoid arthriti7
‘This Is My Decision’: A Qualitative Study of Individuals' Perspectives on Use of Semaglutide for Weight Loss7
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Effects of rifampicin on porphyrin metabolism in healthy volunteers7
Changes in oral corticosteroid use in asthma treatment—A 20‐year Danish nationwide drug utilisation study7
Individual susceptibility has a major impact on strong association between oxidative stress, defence systems and Parkinson's disease7
The Molecular and Clinical Impact of Atorvastatin Exposure on Paclitaxel Neurotoxicity in Sensory Neurons and Cancer Patients7
Issue Information7
Berberine regulates pulmonary inflammatory microenvironment and decreases collagen deposition in response to bleomycin‐induced pulmonary fibrosis in mice6
Downregulation of GPR160 inhibits the progression of glioma through suppressing epithelial to mesenchymal transition (EMT) biomarkers6
Multiple regulation and targeting effects of borneol in the neurovascular unit in neurodegenerative diseases6
Gentiopicroside Attenuated Dopaminergic Neurodegeneration via Inhibiting Neuroinflammatory Responses and Ferroptosis in Experimental Models of Parkinson's Disease6
The effectiveness and safety of botulinum toxin injections for managing motor disorders of patients with Parkinson's disease: A meta‐analysis of randomized controlled trials6
Application of Artificial Intelligence in the Development of Traditional Chinese Medicine6
Toxicity and therapy outcome associations in LIG3, SLCO1B3, ABCB1, OPRM1 and GSTP1 in high‐grade serous ovarian cancer6
Development of a Deprescribing Intervention for Proton Pump Inhibitors in Primary Care: A Co‐Design Approach With General Practitioners and Patients6
Methylophiopogonanone A is a naturally occurring broad‐spectrum inhibitor against human UDP‐glucuronosyltransferases: Inhibition behaviours and implication in herb‐drug interactions6
Dementia and neurodegenerative diseases: What is known and what is promising at the cellular and molecular level6
Studies on the mode of action of synthetic diindolylmethane derivatives against triple negative breast cancer cells6
Healthcare Providers' Perspectives on Antidepressant Discontinuation: A Focus Group Study6
Growth differentiation factor 15 is dispensable for acetaminophen‐induced liver injury in mice6
Corrigendum6
Special Collection: Mechanisms of Vasodilatation Endothelium‐Dependent Hyperpolarization (MOVD/EDH2024)6
Paroxetine alleviates ulcerative colitis in mice via restoring intestinal microbiota homeostasis and metabolism6
Effect of stearyl alcohol on imiquimod‐induced psoriasis‐like skin inflammation in mice6
Issue Information6
High Throughput Pharmacovigilance Screening for Roflumilast Adverse Effects in Real‐World Settings: A Sequence Symmetry Analysis6
Plasma NGAL, suPAR, KIM‐1 and GDF‐15 for Improving Glomerular Filtration Rate Estimation in Older Hospitalized Patients6
Pharmacokinetics of free and total mycophenolic acid in paediatric and adult renal transplant recipients: Exploratory analysis of the effects of clinical factors and gene variants6
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Correction to ‘Β‐LAPachone Ameliorates Doxorubicin‐Induced Cardiotoxicity via Regulating Autophagy and Nrf2 Signalling Pathways in Mice’5
The Pathobiology of Cerebrovascular Lesions in CADASIL Small Vessel Disease5
Traditional Chinese Medicine for Inhibiting Ferroptosis in Ischemic‐Related Diseases5
Therapeutic benefit of melatonin in 5‐fluorouracil‐induced renal and hepatic injury5
Eugenol Alleviates Cerebral Ischemia–Reperfusion Injury in Mice by Promoting the Phagocytosis of Microglia via Up‐Regulating Tripartite Motif Protein 595
α‐Lipoic acid up‐regulates gene expression but reduces protein levels of fibroblast growth factor 21 in HepG2 cells5
Bruceine A Inhibits Cell Proliferation by Targeting the USP13/PARP1 Signalling Pathway in Multiple Myeloma5
Issue Information5
Multi‐Target Renal Protection of Wine‐Processed Polygonatum sibiricum Against Cisplatin‐Induced Nephrotoxicity: Integrated Phytochemistry, Network Pharmacology and Experimental Valid5
Study of the mechanism underlying the role of PINK1/Parkin in the formic acid‐induced autophagy of PC12 cells5
Issue Information5
Issue Information5
A review on the new age methodologies for early detection of Alzheimer's and Parkinson's disease5
Ten deprescribing articles you should know about: A guide for newcomers to the field5
Foetal Exposure to Phthalates and Endocrine Effects on the Leydig Cell5
Biomarkers of Parkinson's disease in perspective of early diagnosis and translation of neurotrophic therapies5
Vancomycin audit in the paediatric population: Patterns of use and appropriateness of therapeutic drug monitoring5
CYP3A4*22 and bleeding risk in ticagrelor users5
Antitumour effect of odoroside A and its derivative on human leukaemia cells through the ROS/JNK pathway5
The role of decision tree and machine learning models for outcome prediction of bupropion exposure: A nationwide analysis of more than 14 000 patients in the United States5
LW‐AFC Protects Against Neurological and Neuropsychiatric Effects of SARS‐CoV‐2 Spike Protein in Mice5
Emergency Department Visits due to Medication Overdose in a Finnish University Hospital5
Exploratory pharmacovigilance with machine learning in big patient data: A focused scoping review5
Welcome to Basic & Clinical Pharmacology & Toxicology 20245
Deaths caused by medication in persons not using illicit narcotic drugs: An autopsy study from Western Denmark5
Atenolol and mortality events in patients with chronic kidney disease: Analysis of data from the Japanese Adverse Drug Event Report database5
Association between patient attitudes towards deprescribing and subsequent prescription changes5
Gastroprotective effect of sumatriptan against indomethacin‐, stress‐ and ethanol‐induced gastric damage in male rats: Possible modulatory role of 5‐hydroxytryptamine 1B/1D receptors and pro‐inflammat5
Investigating the P53‐dependent anti‐cancer effect of ibutamoren in human cancer cell lines5
Initiation of Anticoagulants During the COVID‐19 Pandemic in Sweden: An Interrupted Time Series Analysis5
Triptolide alleviates collagen‐induced arthritis in mice by modulating Treg/Th17 imbalance through the JAK/PTEN‐STAT3 pathway5
Categorization of deprescribing communication tools: A scoping review5
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