OOIR: Observatory of International Research

Papers

(The H4-Index of Acta Biomaterialia is 74. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-11-01 to 2024-11-01.)

Article	Citations
Exosomes from TNF-α-treated human gingiva-derived MSCs enhance M2 macrophage polarization and inhibit periodontal bone loss	260
Sprayable hydrogel dressing accelerates wound healing with combined reactive oxygen species-scavenging and antibacterial abilities	244
Antibacterial adhesive self-healing hydrogels to promote diabetic wound healing	212
3D and 4D printing in dentistry and maxillofacial surgery: Printing techniques, materials, and applications	208
Macrophage phenotypes in tissue repair and the foreign body response: Implications for biomaterial-based regenerative medicine strategies	202
Recent advances in PLGA-based biomaterials for bone tissue regeneration	181
A composite hydrogel with co-delivery of antimicrobial peptides and platelet-rich plasma to enhance healing of infected wounds in diabetes	168
PEG-based thermosensitive and biodegradable hydrogels	165
From influenza to COVID-19: Lipid nanoparticle mRNA vaccines at the frontiers of infectious diseases	163
The multifaceted roles of macrophages in bone regeneration: A story of polarization, activation and time	161
The immune microenvironment in cartilage injury and repair	160
A 3D-printed PRP-GelMA hydrogel promotes osteochondral regeneration through M2 macrophage polarization in a rabbit model	155
Biological properties of copper-doped biomaterials for orthopedic applications: A review of antibacterial, angiogenic and osteogenic aspects	144
An injectable hydrogel using an immunomodulating gelator for amplified tumor immunotherapy by blocking the arginase pathway	136
Berberine-loaded M2 macrophage-derived exosomes for spinal cord injury therapy	133
Graphene and graphene oxide for bio-sensing: General properties and the effects of graphene ripples	129
Strategies to use fibrinogen as bioink for 3D bioprinting fibrin-based soft and hard tissues	129
The protein corona and its effects on nanoparticle-based drug delivery systems	128
3D bioprinting of mechanically tuned bioinks derived from cardiac decellularized extracellular matrix	125
Microneedle-mediated transdermal drug delivery for treating diverse skin diseases	124
Dual stimuli-responsive metal-organic framework-based nanosystem for synergistic photothermal/pharmacological antibacterial therapy	121
Glucose-responsive multifunctional metal–organic drug-loaded hydrogel for diabetic wound healing	121
VH298-loaded extracellular vesicles released from gelatin methacryloyl hydrogel facilitate diabetic wound healing by HIF-1α-mediated enhancement of angiogenesis	120
3D bioprinting of graphene oxide-incorporated cell-laden bone mimicking scaffolds for promoting scaffold fidelity, osteogenic differentiation and mineralization	118
Engineered exosome-like nanovesicles suppress tumor growth by reprogramming tumor microenvironment and promoting tumor ferroptosis	117

Scaffolds with controlled release of pro-mineralization exosomes to promote craniofacial bone healing without cell transplantation	113
Control of innate immune response by biomaterial surface topography, energy, and stiffness	111
Injectable adaptive self-healing hyaluronic acid/poly (γ-glutamic acid) hydrogel for cutaneous wound healing	110
Chitosan-based multifunctional flexible hemostatic bio-hydrogel	107
Biodegradable Zn–Cu alloys show antibacterial activity against MRSA bone infection by inhibiting pathogen adhesion and biofilm formation	107
The tissue origin effect of extracellular vesicles on cartilage and bone regeneration	106
Chemical design of nanozymes for biomedical applications	104
Treatment of inflammatory bone loss in periodontitis by stem cell-derived exosomes	104
Immunomodulatory bioactive glasses for tissue regeneration	103
ZIF-8 modified multifunctional injectable photopolymerizable GelMA hydrogel for the treatment of periodontitis	103
Orchestrating soft tissue integration at the transmucosal region of titanium implants	102
Calcium phosphate cements: Optimization toward biodegradability	101
Multi-functional silica-based mesoporous materials for simultaneous delivery of biologically active ions and therapeutic biomolecules	101
Processing, mechanical properties and bio-applications of silk fibroin-based high-strength hydrogels	97
Sulfated chitosan rescues dysfunctional macrophages and accelerates wound healing in diabetic mice	96
Hyaluronic acid-based glucose-responsive antioxidant hydrogel platform for enhanced diabetic wound repair	94
Polyphenols as a versatile component in tissue engineering	93
A photo-crosslinkable cartilage-derived extracellular matrix bioink for auricular cartilage tissue engineering	93
An injectable, self-healing phenol-functionalized chitosan hydrogel with fast gelling property and visible light-crosslinking capability for 3D printing	93
Understanding and optimizing the antibacterial functions of anodized nano-engineered titanium implants	93
4D Printing of shape-memory polymeric scaffolds for adaptive biomedical implantation	91
Hydrogel-based colorectal cancer organoid co-culture models	90
3D bioprinting of prevascularised implants for the repair of critically-sized bone defects	90
Quaternized carbon quantum dots with broad-spectrum antibacterial activity for the treatment of wounds infected with mixed bacteria	89
Modification of polyetheretherketone implants: From enhancing bone integration to enabling multi-modal therapeutics	88
Recent developments in natural and synthetic polymeric drug delivery systems used for the treatment of osteoarthritis	88
2D Ti3C2TxMXene couples electrical stimulation to promote proliferation and neural differentiation of neural stem cells	87
Personalized 3D printed bone scaffolds: A review	87
Peptide-guided resiquimod-loaded lignin nanoparticles convert tumor-associated macrophages from M2 to M1 phenotype for enhanced chemotherapy	86
Advances in bioactive glass-containing injectable hydrogel biomaterials for tissue regeneration	86
Advanced materials for drug delivery across mucosal barriers	85
Electrically conductive 3D printed Ti3C2T MXene-PEG composite constructs for cardiac tissue engineering	85
3D printed hydrogel/PCL core/shell fiber scaffolds with NIR-triggered drug release for cancer therapy and wound healing	85
Hypoxia-pretreated ADSC-derived exosome-embedded hydrogels promote angiogenesis and accelerate diabetic wound healing	84
Biomimetic nanoengineered scaffold for enhanced full-thickness cutaneous wound healing	84
A review of the physiological impact of rare earth elements and their uses in biomedical Mg alloys	83
Biomineralization process in hard tissues: The interaction complexity within protein and inorganic counterparts	83
Multifunctional ultrasmall AgNP hydrogel accelerates healing of S. aureus infected wounds	82
Preparation of NIR-responsive, ROS-generating and antibacterial black phosphorus quantum dots for promoting the MRSA-infected wound healing in diabetic rats	81
Three-dimensional bioprinting of a full-thickness functional skin model using acellular dermal matrix and gelatin methacrylamide bioink	81
Self-healing, stretchable, and highly adhesive hydrogels for epidermal patch electrodes	80
Conductive biomaterials for cardiac repair: A review	80
Integrating biomaterials and food biopolymers for cultured meat production	80
Titanium carbide MXene-based hybrid hydrogel for chemo-photothermal combinational treatment of localized bacterial infection	80
Biological and mechanical performance and degradation characteristics of calcium phosphate cements in large animals and humans	78
Bone marrow stromal cells stimulated by strontium-substituted calcium silicate ceramics: release of exosomal miR-146a regulates osteogenesis and angiogenesis	77
Immunomodulatory biomaterials and their application in therapies for chronic inflammation-related diseases	77
Bio-inspired flexible electronics for smart E-skin	75
Photo-crosslinkable amniotic membrane hydrogel for skin defect healing	75
Functional fillers for dental resin composites	74

Exosome detection via surface-enhanced Raman spectroscopy for cancer diagnosis	74
A double-crosslinked self-healing antibacterial hydrogel with enhanced mechanical performance for wound treatment	74