Expert Opinion on Drug Delivery

Article	Citations
Metallic nanoparticles as drug delivery system for the treatment of cancer	68
Microneedle arrays for the treatment of chronic wounds	67
Multifunctional and stimuli-responsive nanocarriers for targeted therapeutic delivery	66
Poly(beta-amino ester)s as gene delivery vehicles: challenges and opportunities	61
Platinum-based chemotherapy in combination with PD-1/PD-L1 inhibitors: preclinical and clinical studies and mechanism of action	60
Co-amorphous systems for the delivery of poorly water-soluble drugs: recent advances and an update	54
Release mechanisms and applications of drug delivery systems for extended-release	50
Advances in lyotropic liquid crystal systems for skin drug delivery	50
The latest advances of cisplatin liposomal formulations: essentials for preparation and analysis	49
Nicotine forms: why and how do they matter in nicotine delivery from electronic cigarettes?	47
Wound dressings as growth factor delivery platforms for chronic wound healing	44
A review of recent advances in nanodiamond-mediated drug delivery in cancer	41
Doxorubicin-loaded graphene oxide nanocomposites in cancer medicine: stimuli-responsive carriers, co-delivery and suppressing resistance	40
Manipulative magnetic nanomedicine: the future of COVID-19 pandemic/endemic therapy	40
Surface-modified polymeric nanoparticles for drug delivery to cancer cells	38
Trends in nanotechnology-based delivery systems for dermal targeting of drugs: an enticing approach to offset psoriasis	38
Transient Permeation Enhancer® (TPE®) technology for oral delivery of octreotide: a technological evaluation	38
Electrospun nanofiber-based drug delivery platform: advances in diabetic foot ulcer management	37
Advances in pulmonary drug delivery devices for the treatment of chronic obstructive pulmonary disease	37
Emerging potential of niosomes in ocular delivery	37
Co-delivery of a RanGTP inhibitory peptide and doxorubicin using dual-loaded liposomal carriers to combat chemotherapeutic resistance in breast cancer cells	36
Nose-to-brain delivery of antipsychotics using nanotechnology: a review	36
Penetratin-modified lutein nanoemulsion in-situ gel for the treatment of age-related macular degeneration	35
Drug delivery to macrophages: a review of nano-therapeutics targeted approach for inflammatory disorders and cancer	35
Microneedles for drug delivery: recent advances in materials and geometry for preclinical and clinical studies	35

Intestinal permeation enhancers to improve oral bioavailability of macromolecules: reasons for low efficacy in humans	35
Liposomes as vehicles for topical ophthalmic drug delivery and ocular surface protection	34
Enhancing nanoparticle penetration through airway mucus to improve drug delivery efficacy in the lung	34
Targeted drug nanocrystals for pulmonary delivery: a potential strategy for lung cancer therapy	33
Current status of the development of intravesical drug delivery systems for the treatment of bladder cancer	33
Clay nanoparticles as pharmaceutical carriers in drug delivery systems	33
Orally administered self-emulsifying drug delivery system in disease management: advancement and patents	33
The perspectives of intra-articular therapy in the management of osteoarthritis	33
Commercialization challenges for drug eluting contact lenses	32
Circumventing antimicrobial-resistance and preventing its development in novel, bacterial infection-control strategies	32
Advancing of titanium medical implants by surface engineering: recent progress and challenges	31
Alginate-based drug oral targeting using bio-micro/nano encapsulation technologies	29
Long-acting approaches for delivery of antiretroviral drugs for prevention and treatment of HIV: a review of recent research	29
Biomechanics of suprachoroidal drug delivery: From benchtop to clinical investigation in ocular therapies	29
Extruded filaments derived 3D printed medicated skin patch to mitigate destructive pulmonary tuberculosis: design to delivery	29
Factors affecting the dynamics and heterogeneity of the EPR effect: pathophysiological and pathoanatomic features, drug formulations and physicochemical factors	28
Mechanistic view of skin electroporation – models and dosimetry for successful applications: an expert review	28
Intraperitoneal chemotherapy for peritoneal metastases: an expert opinion	28
Applications of Fourier transform infrared spectroscopy to pharmaceutical preparations	28
Self-assembled non-covalent protein-drug nanoparticles: an emerging delivery platform for anti-cancer drugs	27
Novel formulations of metal-organic frameworks for controlled drug delivery	26
Management of epileptic disorders using nanotechnology-based strategies for nose-to-brain drug delivery	26
Lipid-based nano delivery of Tat-peptide conjugated drug or vaccine–promising therapeutic strategy for SARS-CoV-2 treatment	26
Oral co-delivery nanoemulsion of 5-fluorouracil and curcumin for synergistic effects against liver cancer	26
An update on the applications and characteristics of magnetic iron oxide nanoparticles for drug delivery	26
Drug-eluting embolic microspheres: State-of-the-art and emerging clinical applications	25
Biphasic drug release from electrospun structures	25
Polysaccharide nanoparticles for oral controlled drug delivery: the role of drug–polymer and interpolymer interactions	25
Nanofibers as drug-delivery systems for infection control in dentistry	24
Trends in nanoformulations for atopic dermatitis treatment	24
Mesenchymal stem/stromal cells as next-generation drug delivery vehicles for cancer therapeutics	24
Targeting the undruggable: emerging technologies in antibody delivery against intracellular targets	24
Ultra-small-size Astragaloside-IV loaded lipid nanocapsules eye drops for the effective management of dry age-related macular degeneration	23
Analytical tools and evaluation strategies for nanostructured lipid carrier-based topical delivery systems	23
Polymeric nanostructure vaccines: applications and challenges	23
Can 3D printing of oral drugs help fight the current COVID-19 pandemic (and similar crisis in the future)?	23
Green nanomedicine: the path to the next generation of nanomaterials for diagnosing brain tumors and therapeutics?	23
Peptides, proteins and nanotechnology: a promising synergy for breast cancer targeting and treatment	22
Delivery of genome editing tools: A promising strategy for HPV-related cervical malignancy therapy	22
Nano Antiviral Photodynamic Therapy: a Probable Biophysicochemical Management Modality in SARS-CoV-2	22
An update on cell-penetrating peptides with intracellular organelle targeting	21
Recent advances in herbal combination nanomedicine for cancer: delivery technology and therapeutic outcomes	21
Recent trends in praziquantel nanoformulations for helminthiasis treatment	21
Current trends in PLGA based long-acting injectable products: The industry perspective	21
A versatile nanoplatform for synergistic chemo-photothermal therapy and multimodal imaging against breast cancer	20
Preparation and characterization of cyclodextrin nanosponges for bortezomib delivery	20
Biomimetic cancer cell membrane-coated nanosystems as next-generation cancer therapies	20
Fabrication of versatile targeted lipopolymersomes for improved camptothecin efficacy against colon adenocarcinoma in vitro and in vivo	20
The use of cyclodextrin inclusion complexes to improve anticancer drug profiles: a systematic review	20
The sustainability of emerging technologies for use in pharmaceutical manufacturing	20

Recent advances in intraocular and novel drug delivery systems for the treatment of diabetic retinopathy	20
A clinical review of the t:slim X2 insulin pump	19
Nucleic acid-loaded lipid-polymer nanohybrids as novel nanotherapeutics in anticancer therapy	18
Port delivery system: a novel drug delivery platform to treat retinal diseases	18
Advancing human in vitro pulmonary disease models in preclinical research: opportunities for lung-on-chips	18
Overcoming challenges for development of amorphous powders for inhalation	18
Application of chloroquine as an endosomal escape enhancing agent: new frontiers for an old drug	18
Drug eluting implants in pharmaceutical development and clinical practice	17
PROMOTING SAFE AND EFFECTIVE USE OF AEROSOL DEVICES IN COVID-19:RISKS AND SUGGESTIONS FOR VIRAL TRANSMISSION	17
Nanoemulsion-based dosage forms for the transdermal drug delivery applications: A review of recent advances	17
Application of PLGA nano/microparticle delivery systems for immunomodulation and prevention of allotransplant rejection	17
Manufacturing of hybrid drug delivery systems by utilizing the fused filament fabrication (FFF) technology	17
Electrospun fibers: an innovative delivery method for the treatment of bone diseases	17
Magnetoliposomes: recent advances in the field of controlled drug delivery	17
Revisiting techniques to evaluate drug permeation through skin	17
Development of syringes and vials for delivery of biologics: current challenges and innovative solutions	17
CD44 receptor-targeted novel drug delivery strategies for rheumatoid arthritis therapy	16
Current trends on cannabidiol delivery systems: where are we and where are we going?	16
Layer-by-Layer technique as a versatile tool for gene delivery applications	16
Bergamot oil as an integral component of nanostructured lipid carriers and a photosensitizer for photodynamic treatment of vitiligo: Characterization and clinical experimentation	16
Novel drug delivery methods for improving efficacy of endometriosis treatments	16
Edible plant-derived nanotherapeutics and nanocarriers: recent progress and future directions	16
Recent advances in iron oxide nanoparticles for brain cancer theranostics: from in vitro to clinical applications	16
Coenzyme Q10 phospholipidic vesicular formulations for treatment of androgenic alopecia:ex vivopermeation and clinical appraisal	16
Treatment challenges and delivery systems in immunomodulation and probiotic therapies for periodontitis	16
Current status and future directions of hepatocellular carcinoma-targeted nanoparticles and nanomedicine	16
Inhaled cytotoxic chemotherapy: clinical challenges, recent developments, and future prospects	16
Self-assembled block polymer aggregates in selective solution: controllable morphology transitions and their applications in drug delivery	16
Polysaccharide-based hydrogels for drug delivery and wound management: a review	15
Real-time quantitative monitoring of in vitro nasal drug delivery by a nasal epithelial mucosa-on-a-chip model	15
Current trends in the use of human serum albumin for drug delivery in cancer	15
The ins and outs of drug-releasing vaginal rings: a literature review of expulsions and removals	15
Research Progress in Bioinspired Drug Delivery Systems	15
Nanoparticle-mediated therapeutic compounds delivery to glioblastoma	15
Microfluidic production of mRNA-loaded lipid nanoparticles for vaccine applications	15
Thermosensitive liposomes: a promising step toward localised chemotherapy	15
Recent advances in graphene-family nanomaterials for effective drug delivery and phototherapy	15
Nanoparticles as phytochemical carriers for cancer treatment: News of the last decade	15
3D-printed porous tantalum: recent application in various drug delivery systems to repair hard tissue defects	14
Microneedles for transdermal drug delivery using clay-based composites	14
Vascular and extracellular matrix remodeling by physical approaches to improve drug delivery at the tumor site	14
Unleashing the potential of cell membrane-based nanoparticles for COVID-19 treatment and vaccination	14
Targeted drug therapy in non-small cell lung cancer: Clinical significance and possible solutions-Part I	13
Progress of delivery methods for CRISPR-Cas9	13
Harnessing CD47 mimicry to inhibit phagocytic clearance and enhance anti-tumor efficacy of nanoliposomal doxorubicin	13
Polyaminoacid-based nanocarriers: a review of the latest candidates for oral drug delivery	13
Topical preservative-free ophthalmic treatments: an unmet clinical need	13
Emerging trends in microneedle-based drug delivery strategies for the treatment of rheumatoid arthritis	13
Macrophage targeted nanocarrier delivery systems in HIV therapeutics	13
Emerging skin-targeted drug delivery strategies to engineer immunity: A focus on infectious diseases	13
Targeted drug therapy in nonsmall cell lung cancer: clinical significance and possible solutions-part II (role of nanocarriers)	13
Long-acting HIV pre-exposure prophylaxis (PrEP) approaches: recent advances, emerging technologies, and development challenges	13
Advances in the use of cell penetrating peptides for respiratory drug delivery	13
Oral controlled release dosage forms: dissolution versus diffusion	13
Orally delivered targeted nanotherapeutics for the treatment of colorectal cancer	13
Topical drug delivery to the retina: obstacles and routes to success	12
Nanocrystals for controlled delivery: state of the art and approved drug products	12
Biomedical applications of PLGA nanoparticles in nanomedicine: advances in drug delivery systems and cancer therapy	12
Preclinical evaluations of Norcantharidin liposome and emulsion hybrid delivery system with improved encapsulation efficiency and enhanced antitumor activity	12
Transferrin receptor-mediated liposomal drug delivery: recent trends in targeted therapy of cancer	12
Nose-to-brain drug delivery for the treatment of Alzheimer’s disease: current advancements and challenges	12
Orodispersible tablets for pediatric drug delivery: current challenges and recent advances	12
Triumph against cancer: invading colorectal cancer with nanotechnology	12
Safety of recombinant human hyaluronidase PH20 for subcutaneous drug delivery	12
Polymer-based thermoresponsive hydrogels for controlled drug delivery	11
Are inhaled mRNA vaccines safe and effective? A review of preclinical studies	11
Tumor microenvironment-responsive size-switchable drug delivery nanosystems	11
Preparation and characterization of a novel thermosensitive and bioadhesive cephalexin nanohydrogel: a promising platform for topical antibacterial delivery	11
Preclinical developments of enzyme-loaded red blood cells	11
Sacubitril-valsartan cocrystal revisited: role of polymer excipients in the formulation	11
Long-acting injectable formulation technologies: challenges and opportunities for the delivery of fragile molecules	11
Intratumorally anchored cytokine therapy	11
Research progress in tumor targeted immunotherapy	11
Transarterial drug delivery for liver cancer: numerical simulations and experimental validation of particle distribution in patient-specific livers	11
Profiling of drug crystallization in the skin	11
Oleuropein as a novel topical antipsoriatic nutraceutical: formulation in microemulsion nanocarrier and exploratory clinical appraisal	11
Inhaled fixed-dose combination powders for the treatment of respiratory infections	11
Smart design of patient-centric long-acting products: from preclinical to marketed pipeline trends and opportunities	11
Atropine in topical formulations for the management of anterior and posterior segment ocular diseases	11
Loco-regional drug delivery in oncology: current clinical applications and future translational opportunities	10

Novel drug delivery systems of β2 adrenoreceptor agonists to suppress SNCA gene expression and mitochondrial oxidative stress in Parkinson’s disease management	10
The development of peptide-drug conjugates (PDCs) strategies for paclitaxel	10
Consequences of not-shaking and shake-fire delays on the emitted dose of some commercial solution and suspension pressurized metered dose inhalers	10
Drug-eluting stents for the treatment of coronary artery disease: A review of recent advances	10
Dermato-pharmacokinetic: assessment tools for topically applied dosage forms	10
Protein corona: challenges and opportunities for targeted delivery of nanomedicines	10
Targeting efficiency of nanoliposomes on atherosclerotic foam cells: polyethylene glycol-to-ligand ratio effects	10
Phage in cancer treatment – Biology of therapeutic phage and screening of tumor targeting peptide	10
Carbohydrates based stimulus responsive nanocarriers for cancer-targeted chemotherapy: a review of current practices	10
Towards precision nanomedicine for cerebrovascular diseases with emphasis on Cerebral Cavernous Malformation (CCM)	10
Exploring the transformability of polymer-lipid hybrid nanoparticles and nanomaterial-biology interplay to facilitate tumor penetration, cellular uptake and intracellular targeting of anticancer drugs	10
An observational study demonstrating the adherence and ease of use of the injector device, RebiSmart®	9
New insight into brain disease therapy: nanomedicines-crossing blood–brain barrier and extracellular space for drug delivery	9
State-of-the-art of ultrasound-triggered drug delivery from ultrasound-responsive drug carriers	9
Simultaneous pulmonary administration of celecoxib and naringin using a nebulization-friendly nanoemulsion: A device-targeted delivery for treatment of lung cancer	9
Co-delivery system of chemotherapy drugs and active ingredients from natural plants: a brief overview of preclinical research for cancer treatment	9
Nanocarriers-loaded with natural actives as newer therapeutic interventions for treatment of hepatocellular carcinoma	9
Development and characterization of nano-emulsions and nano-emulgels for transdermal delivery of statins	9
Co-processing of small molecule excipients with polymers to improve functionality	9
Current progress of miRNA-derivative nucleotide drugs: modifications, delivery systems, applications	9
Progress and limitations of oral peptide delivery as a potentially transformative therapy	9
Recent advancements in cellulose-based biomaterials for management of infected wounds	9
Cell-laden alginate hydrogels for the treatment of diabetes	9
Liposomes as multifaceted delivery system in the treatment of osteoporosis	9
Molecular targeted nanotheranostics for future individualized cancer treatment	9
Advances in chlorin-based photodynamic therapy with nanoparticle delivery system for cancer treatment	8
An in-depth analysis of novel combinatorial drug therapy via nanocarriers against HIV/AIDS infection and their clinical perspectives: a systematic review	8
Recent progress in therapeutic strategies and biomimetic nanomedicines for rheumatoid arthritis treatment	8
Effect of excipients on oral absorption process according to the different gastrointestinal segments	8
Peptide-based supramolecular assembly drugs toward cancer theranostics	8
A pilot study examining patient preference and satisfaction for ava®, a reusable electronic injection device to administer certolizumab pegol	8
Oral delivery of solid lipid nanoparticles: underlining the physicochemical characteristics and physiological condition affecting the lipolysis rate	8
Combining experimental and computational techniques to understand and improve dry powder inhalers	8
The role of cells and their products in respiratory drug delivery: the past, present, and future	8
Physical transfection technologies for macrophages and dendritic cells in immunotherapy	8
Design and evaluation of chrysin-loaded nanoemulsion against lithium/pilocarpine-induced status epilepticus in rats; emphasis on formulation, neuronal excitotoxicity, oxidative stress, microglia polar	8
Needle-free jet injection of insulin glargine improves glycemic control in patients with type 2 diabetes mellitus: a study based on the flash glucose monitoring system	8
Self-preserving gelatin emulgel containing whole cell probiotic for topical use: preclinical safety, efficacy, and germination studies	8
Prediction of the physical stability of amorphous solid dispersions: relationship of aging and phase separation with the thermodynamic and kinetic models along with characterization techniques	8
Current and novel therapeutic strategies for the management of cystic fibrosis	8
Opportunities in combinational chemo-immunotherapy for breast cancer using nanotechnology: an emerging landscape	8
Pharmacokinetic/pharmacodynamic approaches to drug delivery design for inhalation drugs	7
Designing orodispersible films containing everolimus for enhanced compliance and bioavailability	7
Bioactive molecule carrier systems in endodontics	7
Antibacterial drugs and cyclodextrin inclusion complexes: a patent review	7
A technology evaluation of CVT-301 (Inbrija): an inhalable therapy for treatment of Parkinson’s disease	7
Nanotechnology-based formulations toward the improved topical delivery of anti-acne active ingredients	7
Current strategies for oral delivery of BCS IV drug nanocrystals: challenges, solutions and future trends	7
Design and application of DNA nanostructures for organelle-targeted delivery of anticancer drugs	7
Biodegradable and removable implants for controlled drug delivery and release application	7
Synthesis of a targeted, dual pH and redox-responsive nanoscale coordination polymer theranostic against metastatic breast cancer in vitro and in vivo	7
Nanotechnology: revolutionizing the delivery of drugs to treat age-related macular degeneration	7
Co-delivery of isotretinoin and clindamycin by phospholipid-based mixed micellar system confers synergistic effect for treatment of acne vulgaris	7
All-trans retinoic acid in anticancer therapy: how nanotechnology can enhance its efficacy and resolve its drawbacks	7
A multicenter, open-label study to evaluate the safe and effective use of a new electromechanical auto-injection device for self-injection of certolizumab pegol	7
Drug delivery options and therapeutic advances in the management of erectile dysfunction	6
Recent advances in the development of asenapine formulations	6
Paclitaxel-eluting silicone airway stent for preventing granulation tissue growth and lung cancer relapse in central airway pathologies	6
Advances in soft mist inhalers	6
Baicalin lipid nanocapsules for treatment of glioma: characterization, mechanistic cytotoxicity, and pharmacokinetic evaluation	6
Long-acting ocular drug delivery technologies with clinical precedent	6
Current advances in cell therapeutics: a biomacromolecules application perspective	6
3D printing of bioactive materials for drug delivery applications	6
Interdependency of influential parameters in therapeutic nanomedicine	6
Diabetic eye: associated diseases, drugs in clinic, and role of self-assembled carriers in topical treatment	6
Recent advances in erythrocyte membrane-camouflaged nanoparticles for the delivery of anti-cancer therapeutics	6
Opening eyes to therapeutic perspectives of bioactive polyphenols and their nanoformulations against diabetic neuropathy and related complications	6
The challenges of drug delivery to the esophagus and how to overcome them	6
Emerging local immunomodulatory strategies to circumvent systemic immunosuppression in cell transplantation	6
Bacteria and cells as alternative nano-carriers for biomedical applications	6
Laser microporation facilitates topical drug delivery: a comprehensive review about preclinical development and clinical application	6
Overcoming hydrolytic degradation challenges in topical delivery: non-aqueous nano-emulsions	6
Magnetic nanoparticles: multifunctional tool for cancer therapy	6
Localized, on-demand, sustained drug delivery from biopolymer-based materials	6
Antibiotic uptake through porins located in the outer membrane of Gram-negative bacteria	6
Nanoparticle-based drug delivery for the treatment of traumatic brain injury	6