Expert Opinion on Drug Delivery

Article	Citations
Metallic nanoparticles as drug delivery system for the treatment of cancer	95
Wound dressings as growth factor delivery platforms for chronic wound healing	57
Enhancing nanoparticle penetration through airway mucus to improve drug delivery efficacy in the lung	50
Doxorubicin-loaded graphene oxide nanocomposites in cancer medicine: stimuli-responsive carriers, co-delivery and suppressing resistance	50
Transient Permeation Enhancer® (TPE®) technology for oral delivery of octreotide: a technological evaluation	48
Liposomes as vehicles for topical ophthalmic drug delivery and ocular surface protection	46
Clay nanoparticles as pharmaceutical carriers in drug delivery systems	45
Microneedles for drug delivery: recent advances in materials and geometry for preclinical and clinical studies	44
Factors affecting the dynamics and heterogeneity of the EPR effect: pathophysiological and pathoanatomic features, drug formulations and physicochemical factors	42
An update on the applications and characteristics of magnetic iron oxide nanoparticles for drug delivery	42
Manipulative magnetic nanomedicine: the future of COVID-19 pandemic/endemic therapy	41
Advancing of titanium medical implants by surface engineering: recent progress and challenges	40
Extruded filaments derived 3D printed medicated skin patch to mitigate destructive pulmonary tuberculosis: design to delivery	39
Biomechanics of suprachoroidal drug delivery: From benchtop to clinical investigation in ocular therapies	39
Biomedical applications of PLGA nanoparticles in nanomedicine: advances in drug delivery systems and cancer therapy	37
Drug-eluting embolic microspheres: State-of-the-art and emerging clinical applications	36
Orally administered self-emulsifying drug delivery system in disease management: advancement and patents	36
Current trends in PLGA based long-acting injectable products: The industry perspective	32
The sustainability of emerging technologies for use in pharmaceutical manufacturing	32
Nanoemulsion-based dosage forms for the transdermal drug delivery applications: A review of recent advances	32
Novel formulations of metal-organic frameworks for controlled drug delivery	31
Biphasic drug release from electrospun structures	31
Mesenchymal stem/stromal cells as next-generation drug delivery vehicles for cancer therapeutics	30
Progress of delivery methods for CRISPR-Cas9	27
An update on cell-penetrating peptides with intracellular organelle targeting	27

Recent advances in herbal combination nanomedicine for cancer: delivery technology and therapeutic outcomes	26
Preparation and characterization of cyclodextrin nanosponges for bortezomib delivery	25
Recent trends in praziquantel nanoformulations for helminthiasis treatment	25
Microfluidic production of mRNA-loaded lipid nanoparticles for vaccine applications	25
CD44 receptor-targeted novel drug delivery strategies for rheumatoid arthritis therapy	24
Drug eluting implants in pharmaceutical development and clinical practice	24
Topical drug delivery to the retina: obstacles and routes to success	24
Edible plant-derived nanotherapeutics and nanocarriers: recent progress and future directions	24
Emerging trends in microneedle-based drug delivery strategies for the treatment of rheumatoid arthritis	23
Green nanomedicine: the path to the next generation of nanomaterials for diagnosing brain tumors and therapeutics?	23
Polymer-based thermoresponsive hydrogels for controlled drug delivery	23
Fabrication of versatile targeted lipopolymersomes for improved camptothecin efficacy against colon adenocarcinoma in vitro and in vivo	23
Recent advances in intraocular and novel drug delivery systems for the treatment of diabetic retinopathy	23
Treatment challenges and delivery systems in immunomodulation and probiotic therapies for periodontitis	23
Transferrin receptor-mediated liposomal drug delivery: recent trends in targeted therapy of cancer	23
Application of chloroquine as an endosomal escape enhancing agent: new frontiers for an old drug	23
Current trends in the use of human serum albumin for drug delivery in cancer	22
Long-acting HIV pre-exposure prophylaxis (PrEP) approaches: recent advances, emerging technologies, and development challenges	22
Thermosensitive liposomes: a promising step toward localised chemotherapy	21
Unleashing the potential of cell membrane-based nanoparticles for COVID-19 treatment and vaccination	21
Nose-to-brain drug delivery for the treatment of Alzheimer’s disease: current advancements and challenges	21
Development of syringes and vials for delivery of biologics: current challenges and innovative solutions	21
Revisiting techniques to evaluate drug permeation through skin	21
Nanoparticles as phytochemical carriers for cancer treatment: News of the last decade	20
Current trends on cannabidiol delivery systems: where are we and where are we going?	20
Polysaccharide-based hydrogels for drug delivery and wound management: a review	20
Current status and future directions of hepatocellular carcinoma-targeted nanoparticles and nanomedicine	20
Nanocrystals for controlled delivery: state of the art and approved drug products	19
Magnetoliposomes: recent advances in the field of controlled drug delivery	19
Port delivery system: a novel drug delivery platform to treat retinal diseases	19
Layer-by-Layer technique as a versatile tool for gene delivery applications	19
Recent advances in iron oxide nanoparticles for brain cancer theranostics: from in vitro to clinical applications	19
Safety of recombinant human hyaluronidase PH20 for subcutaneous drug delivery	19
Topical preservative-free ophthalmic treatments: an unmet clinical need	18
Coenzyme Q10 phospholipidic vesicular formulations for treatment of androgenic alopecia:ex vivopermeation and clinical appraisal	18
Smart design of patient-centric long-acting products: from preclinical to marketed pipeline trends and opportunities	18
Long-acting injectable formulation technologies: challenges and opportunities for the delivery of fragile molecules	17
Real-time quantitative monitoring of in vitro nasal drug delivery by a nasal epithelial mucosa-on-a-chip model	17
Orodispersible tablets for pediatric drug delivery: current challenges and recent advances	17
Triumph against cancer: invading colorectal cancer with nanotechnology	17
Recent advances in graphene-family nanomaterials for effective drug delivery and phototherapy	17
3D-printed porous tantalum: recent application in various drug delivery systems to repair hard tissue defects	17
Simultaneous pulmonary administration of celecoxib and naringin using a nebulization-friendly nanoemulsion: A device-targeted delivery for treatment of lung cancer	16
Bergamot oil as an integral component of nanostructured lipid carriers and a photosensitizer for photodynamic treatment of vitiligo: Characterization and clinical experimentation	16
Advances in soft mist inhalers	16
Atropine in topical formulations for the management of anterior and posterior segment ocular diseases	16
Preclinical evaluations of Norcantharidin liposome and emulsion hybrid delivery system with improved encapsulation efficiency and enhanced antitumor activity	15
Baicalin lipid nanocapsules for treatment of glioma: characterization, mechanistic cytotoxicity, and pharmacokinetic evaluation	15
Sacubitril-valsartan cocrystal revisited: role of polymer excipients in the formulation	15
Tumor microenvironment-responsive size-switchable drug delivery nanosystems	15

Microneedles for transdermal drug delivery using clay-based composites	15
Protein corona: challenges and opportunities for targeted delivery of nanomedicines	15
Magnetic nanoparticles: multifunctional tool for cancer therapy	14
New insight into brain disease therapy: nanomedicines-crossing blood–brain barrier and extracellular space for drug delivery	14
Carbohydrates based stimulus responsive nanocarriers for cancer-targeted chemotherapy: a review of current practices	14
Dermato-pharmacokinetic: assessment tools for topically applied dosage forms	14
Design and evaluation of chrysin-loaded nanoemulsion against lithium/pilocarpine-induced status epilepticus in rats; emphasis on formulation, neuronal excitotoxicity, oxidative stress, microglia polar	14
Inhaled fixed-dose combination powders for the treatment of respiratory infections	14
Intratumorally anchored cytokine therapy	14
Phage in cancer treatment – Biology of therapeutic phage and screening of tumor targeting peptide	13
Are inhaled mRNA vaccines safe and effective? A review of preclinical studies	13
Current strategies for oral delivery of BCS IV drug nanocrystals: challenges, solutions and future trends	13
The impact of common pharmaceutical excipients on the gut microbiota	13
Loco-regional drug delivery in oncology: current clinical applications and future translational opportunities	13
Co-processing of small molecule excipients with polymers to improve functionality	13
Recent progress in therapeutic strategies and biomimetic nanomedicines for rheumatoid arthritis treatment	13
Preclinical developments of enzyme-loaded red blood cells	13
Influence factors on and potential strategies to amplify receptor-mediated nanodrug delivery across the blood–brain barrier	13
State-of-the-art of ultrasound-triggered drug delivery from ultrasound-responsive drug carriers	13
Transarterial drug delivery for liver cancer: numerical simulations and experimental validation of particle distribution in patient-specific livers	13
Drug-eluting stents for the treatment of coronary artery disease: A review of recent advances	12
Localized, on-demand, sustained drug delivery from biopolymer-based materials	12
Research progress in tumor targeted immunotherapy	12
Recent advances in the application of clay-containing hydrogels for hemostasis and wound healing	12
Oleuropein as a novel topical antipsoriatic nutraceutical: formulation in microemulsion nanocarrier and exploratory clinical appraisal	12
Nanocarriers-loaded with natural actives as newer therapeutic interventions for treatment of hepatocellular carcinoma	12
Development and characterization of nano-emulsions and nano-emulgels for transdermal delivery of statins	12
Antibacterial drugs and cyclodextrin inclusion complexes: a patent review	12
Current progress of miRNA-derivative nucleotide drugs: modifications, delivery systems, applications	12
The development of peptide-drug conjugates (PDCs) strategies for paclitaxel	12
Exploring the transformability of polymer-lipid hybrid nanoparticles and nanomaterial-biology interplay to facilitate tumor penetration, cellular uptake and intracellular targeting of anticancer drugs	12
Lidocaine-loaded dissolving microneedle for safe local anesthesia on oral mucosa for dental procedure	11
Self-preserving gelatin emulgel containing whole cell probiotic for topical use: preclinical safety, efficacy, and germination studies	11
Solid lipid nanoparticles and nanostructured lipid carrier-based nanotherapeutics for the treatment of psoriasis	11
The challenges of drug delivery to the esophagus and how to overcome them	11
Nanoparticle-based drug delivery for the treatment of traumatic brain injury	11
Microneedle technology for potential SARS-CoV-2 vaccine delivery	11
Nanotechnology-based formulations toward the improved topical delivery of anti-acne active ingredients	11
Towards precision nanomedicine for cerebrovascular diseases with emphasis on Cerebral Cavernous Malformation (CCM)	11
Updated insight into the characterization of nano-emulsions	11
Progress and limitations of oral peptide delivery as a potentially transformative therapy	11
Re-envisioning the design of nanomedicines: harnessing automation and artificial intelligence	11
Targeting the gut microbiome to control drug pharmacomicrobiomics: the next frontier in oral drug delivery	11
All-trans retinoic acid in anticancer therapy: how nanotechnology can enhance its efficacy and resolve its drawbacks	11
Combining experimental and computational techniques to understand and improve dry powder inhalers	10
Drug delivery in glioblastoma therapy: a review on nanoparticles targeting MGMT-mediated resistance	10
Pharmacokinetic/pharmacodynamic approaches to drug delivery design for inhalation drugs	10
Development and evaluation of a drug-in-adhesive transdermal delivery system for delivery of olanzapine	10
Advances in chlorin-based photodynamic therapy with nanoparticle delivery system for cancer treatment	10
Programmable intratumoral drug delivery to breast cancer using wireless bioelectronic device with electrochemical actuation	10
Enhanced skin drug delivery using dissolving microneedles: a potential approach for the management of skin disorders	10
Synthesis of a targeted, dual pH and redox-responsive nanoscale coordination polymer theranostic against metastatic breast cancer in vitro and in vivo	9
Recent advancements in cellulose-based biomaterials for management of infected wounds	9
Design and application of DNA nanostructures for organelle-targeted delivery of anticancer drugs	9
Emerging local immunomodulatory strategies to circumvent systemic immunosuppression in cell transplantation	9
Oral delivery of solid lipid nanoparticles: underlining the physicochemical characteristics and physiological condition affecting the lipolysis rate	9
3D printing of bioactive materials for drug delivery applications	9
Laser microporation facilitates topical drug delivery: a comprehensive review about preclinical development and clinical application	9
Nanotechnology: revolutionizing the delivery of drugs to treat age-related macular degeneration	9
Effect of excipients on oral absorption process according to the different gastrointestinal segments	9
Bridging the gap between fundamental research and product development of long acting injectable PLGA microspheres	9
Peptide-based supramolecular assembly drugs toward cancer theranostics	9
An in-depth analysis of novel combinatorial drug therapy via nanocarriers against HIV/AIDS infection and their clinical perspectives: a systematic review	9
Needle-free jet injection of insulin glargine improves glycemic control in patients with type 2 diabetes mellitus: a study based on the flash glucose monitoring system	9
Interdependency of influential parameters in therapeutic nanomedicine	9
Enabling faster subcutaneous delivery of larger volume, high viscosity fluids	9
Prediction of the physical stability of amorphous solid dispersions: relationship of aging and phase separation with the thermodynamic and kinetic models along with characterization techniques	9
Opportunities in combinational chemo-immunotherapy for breast cancer using nanotechnology: an emerging landscape	9
Biodegradable and removable implants for controlled drug delivery and release application	9
Liposomes as multifaceted delivery system in the treatment of osteoporosis	9
Colorectal cancer management: strategies in drug delivery	9
Anticancer nanomedicines harnessing tumor microenvironmental components	8
Customized 3D printed multi-drug systems: an effective and efficient approach to polypharmacy	8
Synthetic biodegradable polyesters for implantable controlled-release devices	8
Co-delivery of isotretinoin and clindamycin by phospholipid-based mixed micellar system confers synergistic effect for treatment of acne vulgaris	8
Alginate-based matrix tablets for drug delivery	8
Critical design parameters to develop biomimetic organ-on-a-chip models for the evaluation of the safety and efficacy of nanoparticles	8
Antibiotic uptake through porins located in the outer membrane of Gram-negative bacteria	8
Bacteria and cells as alternative nano-carriers for biomedical applications	8
A technology evaluation of CVT-301 (Inbrija): an inhalable therapy for treatment of Parkinson’s disease	8

Oral delivery of biomacromolecules by overcoming biological barriers in the gastrointestinal tract: an update	8
Diabetic eye: associated diseases, drugs in clinic, and role of self-assembled carriers in topical treatment	8
Recent advances in erythrocyte membrane-camouflaged nanoparticles for the delivery of anti-cancer therapeutics	8
Therapeutic nanocarriers comprising extracellular matrix-inspired peptides and polysaccharides	8
A tale of nucleic acid–ionizable lipid nanoparticles: Design and manufacturing technology and advancement	8
Delivery of mitochondria-containing extracellular vesicles to the BBB for ischemic stroke therapy	8
Nano-sized drug delivery systems to potentiate the immune checkpoint blockade therapy	8
Why mRNA-ionizable LNPs formulations are so short-lived: causes and way-out	8
Sustained release ocular drug delivery systems for glaucoma therapy	8
Recent advances in nanoformulation development of Ritonavir, a key protease inhibitor used in the treatment of HIV-AIDS	8
Current and novel therapeutic strategies for the management of cystic fibrosis	8
An evolving perspective on novel modified release drug delivery systems for inhalational therapy	7
Demystifying particle-based oral vaccines	7
3D-printed solid oral dosage forms for mental and neurological disorders: recent advances and future perspectives	7
Inhaled antifungal therapy: benefits, challenges, and clinical applications	7
Long-acting ocular drug delivery technologies with clinical precedent	7
Current advances in cell therapeutics: a biomacromolecules application perspective	7
Lipoplexes and polyplexes as nucleic acids delivery nanosystems: The current state and future considerations	7
Research progress on detachable microneedles for advanced applications	7
Lipid-based solubilization technology via hot melt extrusion: promises and challenges	7
Drug loaded implantable devices to treat cardiovascular disease	7
Opportunities for enteral drug delivery for neonates, infants, and toddlers: a critical exploration	7
Fluorinated vectors for gene delivery	7
Potential factors affecting free base nicotine yield in electronic cigarette aerosols	7
Formative and Validation Human Factors studies of a new disposable autoinjector for subcutaneous delivery of chronic disease therapies	7
Stimuli-responsive image-guided nanocarriers as smart drug delivery platforms	7
Combinations of chemo-, immuno-, and gene therapies using nanocarriers as a multifunctional drug platform	7
Preparation, thermal response mechanisms and biomedical applications of thermosensitive hydrogels for drug delivery	6
Biomedical Applications of polymeric micelles in the treatment of diabetes mellitus: Current success and future approaches	6
Hydrophobic ion pairing-based self-emulsifying drug delivery systems: a new strategy for improving the therapeutic efficacy of water-soluble drugs	6
Opening eyes to therapeutic perspectives of bioactive polyphenols and their nanoformulations against diabetic neuropathy and related complications	6
Delivery of anti-cancer drugs using microbubble-assisted ultrasound in digestive oncology: from preclinical to clinical studies	6
Pediatric inhalation therapy and the aerodynamic rationale for age-based aerosol sizes	6
Potential applications of drug delivery technologies against radiation enteritis	6
Biomaterials-assisted construction of neoantigen vaccines for personalized cancer immunotherapy	6
Nanocarriers in topical photodynamic therapy	6
Nuclear medicine imaging methods as novel tools in the assessment of pulmonary drug disposition	6
Advances and challenges in nintedanib drug delivery	6
Overcoming hydrolytic degradation challenges in topical delivery: non-aqueous nano-emulsions	6
Solid lipid nanoparticles: a promising tool for insulin delivery	6
Transdermal delivery via medical device technologies	6
The industrial design, translation, and development strategies for long-acting peptide delivery	6
siRNA therapeutics: insights, challenges, remedies and future prospects	5
Platelets for advanced drug delivery in cancer	5
Mucoadhesive drug delivery systems: a promising noninvasive approach to bioavailability enhancement. Part II: formulation considerations	5
Biopredictive tools for the development of injectable drug products	5
Mucoadhesive drug delivery systems: a promising non-invasive approach to bioavailability enhancement. Part I: biophysical considerations	5
Novel formulations for topical delivery of tranexamic acid: assessing the need of epidermal targeting for hyperpigmentation disorders	5
The treatment of hepatocellular carcinoma with SP94 modified asymmetrical bilayer lipid-encapsulated Cu(DDC)2 nanoparticles facilitating Cu accumulation in the tumor	5
Engineered exosomes derived from stem cells: a new brain-targeted strategy	5
Delivering monoclonal antibodies via inhalation: a systematic review of clinical trials in asthma and COPD	5
Study of FA12 peptide-modified PEGylated liposomal doxorubicin (PLD) as an effective ligand to target Muc1 in mice bearing C26 colon carcinoma: in silico, in vitro, and in vivo study	5
Accelerating the development of vaccine microarray patches for epidemic response and equitable immunization coverage requires investment in microarray patch manufacturing facilities	5
Exploring new frontiers in drug delivery with minimally invasive microneedles: fabrication techniques, biomedical applications, and regulatory aspects	5
Nose to brain delivery of naringin-loaded chitosan nanoparticles for potential use in oxaliplatin-induced chemobrain in rats: impact on oxidative stress, cGAS/STING and HMGB1/RAGE/TLR2/MYD88 inflammat	5
Recent progress in antibody-based therapeutics for triple-negative breast cancer	5
Oral nanoparticulate drug delivery systems for the treatment of intestinal bowel disease and colorectal cancer	5
Nanotechnology-enabled gene delivery for cancer and other genetic diseases	5
Ferulic acid’s therapeutic odyssey: nano formulations, pre-clinical investigations, and patent perspective	5
Shaping the future from the small scale: dry powder inhalation of CRISPR-Cas9 lipid nanoparticles for the treatment of lung diseases	5
Nasal delivery as a strategy for the prevention and treatment of COVID-19	5
The engineering challenges and opportunities when designing potent ionizable materials for the delivery of ribonucleic acids	5