Immunity & Ageing

Papers
(The TQCC of Immunity & Ageing is 14. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-12-01 to 2025-12-01.)
ArticleCitations
Natural IgG antibodies to β amyloid are decreased in patients with Parkinson’s disease242
Review of evidence linking exposure to environmental stressors and associated alterations in the dynamics of immunosenescence (ISC) with the global increase in multiple sclerosis (MS)107
Influenza virus infection exacerbates gene expression related to neurocognitive dysfunction in brains of old mice64
Pentraxin-3 and C-reactive protein plasma levels predict survival in older adults with or without metabolic syndrome – results of the PolSenior2 substudy59
The effects of high plasma levels of Aβ1-42 on mononuclear macrophage in mouse models of Alzheimer’s disease58
Cumulative physiological stress is associated with age-related changes to peripheral T lymphocyte subsets in healthy humans55
Different peripheral expression patterns of the nicotinic acetylcholine receptor in dementia with Lewy bodies and Alzheimer’s disease54
Compositional analysis of lymphocytes and their relationship with health outcomes: findings from the health and retirement study54
Fundamental and frontier research of immune responses to influenza vaccines in human aging: from cross-sectional and longitudinal studies to clinical trials and the geroscience perspective52
Aging, inflammaging and immunosenescence as risk factors of severe COVID-1950
Exploring the link between fat-soluble vitamins and aging-associated immune system status: a literature review41
Vascular Cell Adhesion Molecule-1 (VCAM-1) contributes to macular fibrosis in neovascular age-related macular degeneration through modulating macrophage functions40
Differential associations of anti-cytomegalovirus antibodies and soluble CD14 levels with immunosenescence in people living with HIV on long term antiretroviral therapy38
Old hematopoietic stem cells retain competence to reconstitute a youthful B cell system that is highly responsive to protein-based vaccination37
TAOK3 limits age-associated inflammation by negatively modulating macrophage differentiation and their production of TNFα36
Immune cell phenotypes and mortality in the Framingham Heart Study35
Aging and the impact of global DNA methylation, telomere shortening, and total oxidative status on sarcopenia and frailty syndrome34
Deciphering the impact of aging on splenic endothelial cell heterogeneity and immunosenescence through single-cell RNA sequencing analysis34
Systemic immune response in young and elderly patients after traumatic brain injury33
Age-dependent immune profile in healthy individuals: an original study, systematic review and meta-analysis32
The neutrophil to lymphocyte ratio associates with markers of Alzheimer’s disease pathology in cognitively unimpaired elderly people31
Association of adipose tissue inflammation and physical fitness in older adults31
Inhibition of the MEK/ERK pathway suppresses immune overactivation and mitigates TDP-43 toxicity in a Drosophila model of ALS31
MicroRNA-425-5p modulates osteoporosis by targeting annexin A229
The aging immune system and all-cause mortality in older americans: differences across sex and race/ethnicity29
The immunosenescence-related factor DOCK11 is involved in secondary immune responses of B cells28
Several areas of overlap between obesity and aging indicate obesity as a biomarker of accelerated aging of human B cell function and antibody responses26
Targeting aging pathways with natural compounds: a review of curcumin, epigallocatechin gallate, thymoquinone, and resveratrol26
Chitosan alleviates ovarian aging by enhancing macrophage phagocyte-mediated tissue homeostasis25
High SARS-CoV-2 antibody levels after three consecutive BNT162b2 booster vaccine doses in nursing home residents25
Characterisation of specific responses to three models of viral antigens in immunocompetent older adults24
The role of blood related inflammatory factors on age-related macular degeneration (AMD)24
Changes in the innate immune response to SARS-CoV-2 with advancing age in humans24
Disrupted mitochondrial morphology and function exacerbate inflammation in elderly-onset ulcerative colitis23
The use of alpha 1 thymosin as an immunomodulator of the response against SARS-Cov223
Correction: Salutary effects of moderate but not high intensity aerobic exercise training on the frequency of peripheral T-cells associated with immunosenescence in older women at high risk of breast 23
Advanced biological age is associated with improved antibody responses in older high-dose influenza vaccine recipients over four consecutive seasons23
Ageing results in an exacerbated inflammatory response to LPS by resident lung cells22
Systemic inflammation as a central player in the initiation and development of Alzheimer’s disease20
Temporal trends, sex differences, and age-related disease influence in Neutrophil, Lymphocyte count and Neutrophil to Lymphocyte-ratio: results from InCHIANTI follow-up study20
Thymic function and survival at advance ages in nursing home residents from Southern Italy20
Different phenotypes of microglia in animal models of Alzheimer disease20
Correction: Neo-epitopes emerging in the degenerative hippocampal granules of aged mice can be recognized by natural IgM auto-antibodies19
Obesity accelerates age defects in B cells, and weight loss improves B cell function19
Inflammatory markers and physical frailty: towards clinical application19
Evidence of telomere attrition and a potential role for DNA damage in systemic sclerosis19
Blood RNA-Seq profiling reveals a set of circular RNAs differentially expressed in frail individuals19
Evaluation of T-cell aging-related immune phenotypes in the context of biological aging and multimorbidity in the Health and Retirement Study18
Sex-specific innate immunity and ageing in long-lived fresh water turtles (Kinosternon flavescens: Kinosternidae)18
Correction: The oldest unvaccinated Covid-19 survivors in South America18
Melatonin enhances NK cell function in aged mice by increasing T-bet expression via the JAK3-STAT5 signaling pathway18
Adiponectin deficiency accelerates brain aging via mitochondria-associated neuroinflammation18
Toll-like receptor 4 (TLR4): new insight immune and aging18
Exercise improves cognitive dysfunction and neuroinflammation in mice through Histone H3 lactylation in microglia18
Crosstalk between adipogenesis and aging: role of polyphenols in combating adipogenic-associated aging16
Attenuation of OX40 signaling suppression by age disrupts peripheral deletion of CD4+ T cells specific for the epidermal autoantigen desmoglein 316
IL-17A promotes the progression of Alzheimer’s disease in APP/PS1 mice16
Aging and chronic inflammation: highlights from a multidisciplinary workshop16
Targeting immunosenesence promotes clearance of senescent cells16
Algorithms for appropriate patient stratification in the face of a new SARS-CoV-2 pandemic16
Senescence-associated secretory phenotypes in mesenchymal cells contribute to cytotoxic immune response in oral lichen planus16
Secreted IgM deficiency alters the retinal landscape enhancing neurodegeneration associated with aging16
The reference ranges and characteristics of lymphocyte parameters and the correlation between lymphocyte parameters and routine health indicators in adults from China16
A subset of gut leukocytes has telomerase-dependent “hyper-long” telomeres and require telomerase for function in zebrafish15
An aging-related immune landscape in the hematopoietic immune system15
MicroRNAs: a crossroad that connects obesity to immunity and aging15
Longitudinal profiling of clonal hematopoiesis provides insight into clonal dynamics15
Heat-killed probiotic Levilactobacillus brevis MKAK9 and its exopolysaccharide promote longevity by modulating aging hallmarks and enhancing immune responses in Caenorhabditis elegans15
Ascorbic acid attenuates immunosenescence and cognitive decline via MYH9-Mediated CD8⁺ T cell differentiation15
Immunogenicity of adjuvanted versus high-dose inactivated influenza vaccines in older adults: a randomized clinical trial15
Correction: A genomic perspective of the aging human and mouse lung with a focus on immune response and cellular senescence14
Impact of NAD+ metabolism on ovarian aging14
Age-stratified circulating immune signatures reveal non-invasive biomarkers for colorectal cancer detection14
Elicitation of protective immune responses against influenza a viruses in elderly ferrets by adjuvanted recombinant universal influenza hemagglutinin vaccines14
Micro nutrients as immunomodulators in the ageing population: a focus on inflammation and autoimmunity14
High sensitivity C-reactive protein and glycated hemoglobin levels as dominant predictors of all-cause dementia: a nationwide population-based cohort study14
The influence of structured physical activity on vaccination response from adults to older individuals: a systematic review on the Immunoinflammatory crosstalk of COVID-1914
The inter-link of ageing, cancer and immunity: findings from real-world retrospective study14
Excessive IL-15 promotes cytotoxic CD4 + CD28− T cell-mediated renal injury in lupus nephritis14
Ageing with HIV-1: immunological challenges for effective vaccination14
Extreme MetaboHealth scores in three cohort studies associate with plasma protein markers for inflammation and cholesterol transport14
C-reactive protein and white blood cell are associated with frailty progression: a longitudinal study14
Shorter telomere length is associated with COVID-19 hospitalization and with persistence of radiographic lung abnormalities14
Potential determinants of antibody responses after vaccination against SARS-CoV-2 in older persons: the Doetinchem Cohort Study14
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