Immunity & Ageing

Papers
(The TQCC of Immunity & Ageing is 14. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-11-01 to 2025-11-01.)
ArticleCitations
The effects of high plasma levels of Aβ1-42 on mononuclear macrophage in mouse models of Alzheimer’s disease223
Influenza virus infection exacerbates gene expression related to neurocognitive dysfunction in brains of old mice99
Pentraxin-3 and C-reactive protein plasma levels predict survival in older adults with or without metabolic syndrome – results of the PolSenior2 substudy63
Natural IgG antibodies to β amyloid are decreased in patients with Parkinson’s disease55
Cumulative physiological stress is associated with age-related changes to peripheral T lymphocyte subsets in healthy humans55
Review of evidence linking exposure to environmental stressors and associated alterations in the dynamics of immunosenescence (ISC) with the global increase in multiple sclerosis (MS)54
Different peripheral expression patterns of the nicotinic acetylcholine receptor in dementia with Lewy bodies and Alzheimer’s disease53
Aging, inflammaging and immunosenescence as risk factors of severe COVID-1952
Differential associations of anti-cytomegalovirus antibodies and soluble CD14 levels with immunosenescence in people living with HIV on long term antiretroviral therapy52
Compositional analysis of lymphocytes and their relationship with health outcomes: findings from the health and retirement study43
Vascular Cell Adhesion Molecule-1 (VCAM-1) contributes to macular fibrosis in neovascular age-related macular degeneration through modulating macrophage functions39
Exploring the link between fat-soluble vitamins and aging-associated immune system status: a literature review37
Fundamental and frontier research of immune responses to influenza vaccines in human aging: from cross-sectional and longitudinal studies to clinical trials and the geroscience perspective37
Old hematopoietic stem cells retain competence to reconstitute a youthful B cell system that is highly responsive to protein-based vaccination36
TAOK3 limits age-associated inflammation by negatively modulating macrophage differentiation and their production of TNFα34
Immune cell phenotypes and mortality in the Framingham Heart Study34
Deciphering the impact of aging on splenic endothelial cell heterogeneity and immunosenescence through single-cell RNA sequencing analysis32
Aging and the impact of global DNA methylation, telomere shortening, and total oxidative status on sarcopenia and frailty syndrome32
The aging immune system and all-cause mortality in older americans: differences across sex and race/ethnicity31
Several areas of overlap between obesity and aging indicate obesity as a biomarker of accelerated aging of human B cell function and antibody responses30
Inhibition of the MEK/ERK pathway suppresses immune overactivation and mitigates TDP-43 toxicity in a Drosophila model of ALS30
Chitosan alleviates ovarian aging by enhancing macrophage phagocyte-mediated tissue homeostasis30
Systemic immune response in young and elderly patients after traumatic brain injury29
MicroRNA-425-5p modulates osteoporosis by targeting annexin A228
The neutrophil to lymphocyte ratio associates with markers of Alzheimer’s disease pathology in cognitively unimpaired elderly people28
Association of adipose tissue inflammation and physical fitness in older adults28
Targeting aging pathways with natural compounds: a review of curcumin, epigallocatechin gallate, thymoquinone, and resveratrol24
Characterisation of specific responses to three models of viral antigens in immunocompetent older adults23
The immunosenescence-related factor DOCK11 is involved in secondary immune responses of B cells23
High SARS-CoV-2 antibody levels after three consecutive BNT162b2 booster vaccine doses in nursing home residents23
Age-dependent immune profile in healthy individuals: an original study, systematic review and meta-analysis23
Disrupted mitochondrial morphology and function exacerbate inflammation in elderly-onset ulcerative colitis23
The role of blood related inflammatory factors on age-related macular degeneration (AMD)22
Advanced biological age is associated with improved antibody responses in older high-dose influenza vaccine recipients over four consecutive seasons22
The use of alpha 1 thymosin as an immunomodulator of the response against SARS-Cov222
Changes in the innate immune response to SARS-CoV-2 with advancing age in humans22
Multiple thymi and no thymic involution in naked mole rats?21
Correction: Salutary effects of moderate but not high intensity aerobic exercise training on the frequency of peripheral T-cells associated with immunosenescence in older women at high risk of breast 20
Ageing results in an exacerbated inflammatory response to LPS by resident lung cells20
Blood RNA-Seq profiling reveals a set of circular RNAs differentially expressed in frail individuals20
Thymic function and survival at advance ages in nursing home residents from Southern Italy19
Different phenotypes of microglia in animal models of Alzheimer disease19
Inflammatory markers and physical frailty: towards clinical application19
Temporal trends, sex differences, and age-related disease influence in Neutrophil, Lymphocyte count and Neutrophil to Lymphocyte-ratio: results from InCHIANTI follow-up study19
Evidence of telomere attrition and a potential role for DNA damage in systemic sclerosis18
Correction: Neo-epitopes emerging in the degenerative hippocampal granules of aged mice can be recognized by natural IgM auto-antibodies18
Obesity accelerates age defects in B cells, and weight loss improves B cell function18
Systemic inflammation as a central player in the initiation and development of Alzheimer’s disease18
Exercise improves cognitive dysfunction and neuroinflammation in mice through Histone H3 lactylation in microglia17
Evaluation of T-cell aging-related immune phenotypes in the context of biological aging and multimorbidity in the Health and Retirement Study17
Crosstalk between adipogenesis and aging: role of polyphenols in combating adipogenic-associated aging17
Correction: The oldest unvaccinated Covid-19 survivors in South America17
Senescence-associated secretory phenotypes in mesenchymal cells contribute to cytotoxic immune response in oral lichen planus17
Aging and chronic inflammation: highlights from a multidisciplinary workshop16
Adiponectin deficiency accelerates brain aging via mitochondria-associated neuroinflammation16
Melatonin enhances NK cell function in aged mice by increasing T-bet expression via the JAK3-STAT5 signaling pathway16
Sex-specific innate immunity and ageing in long-lived fresh water turtles (Kinosternon flavescens: Kinosternidae)16
Toll-like receptor 4 (TLR4): new insight immune and aging15
Immunogenicity of adjuvanted versus high-dose inactivated influenza vaccines in older adults: a randomized clinical trial15
Impact of NAD+ metabolism on ovarian aging15
IL-17A promotes the progression of Alzheimer’s disease in APP/PS1 mice15
Secreted IgM deficiency alters the retinal landscape enhancing neurodegeneration associated with aging15
The reference ranges and characteristics of lymphocyte parameters and the correlation between lymphocyte parameters and routine health indicators in adults from China15
Heat-killed probiotic Levilactobacillus brevis MKAK9 and its exopolysaccharide promote longevity by modulating aging hallmarks and enhancing immune responses in Caenorhabditis elegans15
Attenuation of OX40 signaling suppression by age disrupts peripheral deletion of CD4+ T cells specific for the epidermal autoantigen desmoglein 315
MicroRNAs: a crossroad that connects obesity to immunity and aging15
Targeting immunosenesence promotes clearance of senescent cells15
Algorithms for appropriate patient stratification in the face of a new SARS-CoV-2 pandemic14
Extreme MetaboHealth scores in three cohort studies associate with plasma protein markers for inflammation and cholesterol transport14
An aging-related immune landscape in the hematopoietic immune system14
C-reactive protein and white blood cell are associated with frailty progression: a longitudinal study14
A subset of gut leukocytes has telomerase-dependent “hyper-long” telomeres and require telomerase for function in zebrafish14
Longitudinal profiling of clonal hematopoiesis provides insight into clonal dynamics14
Correction: A genomic perspective of the aging human and mouse lung with a focus on immune response and cellular senescence14
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