Immunity & Ageing

Papers
(The TQCC of Immunity & Ageing is 11. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-05-01 to 2025-05-01.)
ArticleCitations
Cumulative physiological stress is associated with age-related changes to peripheral T lymphocyte subsets in healthy humans122
Natural IgG antibodies to β amyloid are decreased in patients with Parkinson’s disease76
Review of evidence linking exposure to environmental stressors and associated alterations in the dynamics of immunosenescence (ISC) with the global increase in multiple sclerosis (MS)67
Influenza virus infection exacerbates gene expression related to neurocognitive dysfunction in brains of old mice57
The effects of high plasma levels of Aβ1-42 on mononuclear macrophage in mouse models of Alzheimer’s disease53
Exploring the link between fat-soluble vitamins and aging-associated immune system status: a literature review50
Aging, inflammaging and immunosenescence as risk factors of severe COVID-1947
Different peripheral expression patterns of the nicotinic acetylcholine receptor in dementia with Lewy bodies and Alzheimer’s disease46
Vascular Cell Adhesion Molecule-1 (VCAM-1) contributes to macular fibrosis in neovascular age-related macular degeneration through modulating macrophage functions41
Fundamental and frontier research of immune responses to influenza vaccines in human aging: from cross-sectional and longitudinal studies to clinical trials and the geroscience perspective41
Differential associations of anti-cytomegalovirus antibodies and soluble CD14 levels with immunosenescence in people living with HIV on long term antiretroviral therapy38
Correction to: A novel murine model of multi-day moderate ethanol exposure reveals increased intestinal dysfunction and liver inflammation with age35
Compositional analysis of lymphocytes and their relationship with health outcomes: findings from the health and retirement study33
Aging and the impact of global DNA methylation, telomere shortening, and total oxidative status on sarcopenia and frailty syndrome32
Old hematopoietic stem cells retain competence to reconstitute a youthful B cell system that is highly responsive to protein-based vaccination29
TAOK3 limits age-associated inflammation by negatively modulating macrophage differentiation and their production of TNFα28
Immune cell phenotypes and mortality in the Framingham Heart Study27
The immunosenescence-related factor DOCK11 is involved in secondary immune responses of B cells26
Deciphering the impact of aging on splenic endothelial cell heterogeneity and immunosenescence through single-cell RNA sequencing analysis26
Association of adipose tissue inflammation and physical fitness in older adults25
The neutrophil to lymphocyte ratio associates with markers of Alzheimer’s disease pathology in cognitively unimpaired elderly people24
Age-dependent immune profile in healthy individuals: an original study, systematic review and meta-analysis23
MicroRNA-425-5p modulates osteoporosis by targeting annexin A223
Correction to: Classical and lectin complement pathways and markers of inflammation for investigation of susceptibility to infections among healthy older adults23
Inhibition of the MEK/ERK pathway suppresses immune overactivation and mitigates TDP-43 toxicity in a Drosophila model of ALS22
Chitosan alleviates ovarian aging by enhancing macrophage phagocyte-mediated tissue homeostasis22
Systemic immune response in young and elderly patients after traumatic brain injury22
Characterisation of specific responses to three models of viral antigens in immunocompetent older adults21
Several areas of overlap between obesity and aging indicate obesity as a biomarker of accelerated aging of human B cell function and antibody responses21
The use of alpha 1 thymosin as an immunomodulator of the response against SARS-Cov220
High SARS-CoV-2 antibody levels after three consecutive BNT162b2 booster vaccine doses in nursing home residents19
Disrupted mitochondrial morphology and function exacerbate inflammation in elderly-onset ulcerative colitis18
Functional conservation in genes and pathways linking ageing and immunity18
Advanced biological age is associated with improved antibody responses in older high-dose influenza vaccine recipients over four consecutive seasons17
The role of blood related inflammatory factors on age-related macular degeneration (AMD)17
Changes in the innate immune response to SARS-CoV-2 with advancing age in humans17
Blood RNA-Seq profiling reveals a set of circular RNAs differentially expressed in frail individuals16
Thymic function and survival at advance ages in nursing home residents from Southern Italy16
Correction: Salutary effects of moderate but not high intensity aerobic exercise training on the frequency of peripheral T-cells associated with immunosenescence in older women at high risk of breast 16
Ageing results in an exacerbated inflammatory response to LPS by resident lung cells16
Multiple thymi and no thymic involution in naked mole rats?16
Inflammatory markers and physical frailty: towards clinical application15
Correction to: High-dimensional single cell mass cytometry analysis of the murine hematopoietic system reveals signatures induced by ageing and physiological pathogen challenges15
Different phenotypes of microglia in animal models of Alzheimer disease15
May critical molecular cross-talk between indoleamine 2,3-dioxygenase (IDO) and arginase during human aging be targets for immunosenescence control?15
Temporal trends, sex differences, and age-related disease influence in Neutrophil, Lymphocyte count and Neutrophil to Lymphocyte-ratio: results from InCHIANTI follow-up study15
Obesity accelerates age defects in B cells, and weight loss improves B cell function14
Differential immunogenicity of BNT162b2 or ChAdOx1 vaccines after extended-interval homologous dual vaccination in older people14
Evidence of telomere attrition and a potential role for DNA damage in systemic sclerosis14
Exercise improves cognitive dysfunction and neuroinflammation in mice through Histone H3 lactylation in microglia14
Correction: Neo-epitopes emerging in the degenerative hippocampal granules of aged mice can be recognized by natural IgM auto-antibodies14
Sex-specific innate immunity and ageing in long-lived fresh water turtles (Kinosternon flavescens: Kinosternidae)14
Evaluation of T-cell aging-related immune phenotypes in the context of biological aging and multimorbidity in the Health and Retirement Study13
Senescence-associated secretory phenotypes in mesenchymal cells contribute to cytotoxic immune response in oral lichen planus13
Correction: The oldest unvaccinated Covid-19 survivors in South America13
Crosstalk between adipogenesis and aging: role of polyphenols in combating adipogenic-associated aging13
Melatonin enhances NK cell function in aged mice by increasing T-bet expression via the JAK3-STAT5 signaling pathway13
miR-181a-regulated pathways in T-cell differentiation and aging13
Immunogenicity of adjuvanted versus high-dose inactivated influenza vaccines in older adults: a randomized clinical trial12
Adiponectin deficiency accelerates brain aging via mitochondria-associated neuroinflammation12
Heat-killed probiotic Levilactobacillus brevis MKAK9 and its exopolysaccharide promote longevity by modulating aging hallmarks and enhancing immune responses in Caenorhabditis elegans12
Toll-like receptor 4 (TLR4): new insight immune and aging12
Attenuation of OX40 signaling suppression by age disrupts peripheral deletion of CD4+ T cells specific for the epidermal autoantigen desmoglein 312
Aging and chronic inflammation: highlights from a multidisciplinary workshop12
A subset of gut leukocytes has telomerase-dependent “hyper-long” telomeres and require telomerase for function in zebrafish11
Impact of NAD+ metabolism on ovarian aging11
Secreted IgM deficiency alters the retinal landscape enhancing neurodegeneration associated with aging11
Longitudinal profiling of clonal hematopoiesis provides insight into clonal dynamics11
Is mechanical loading essential for exercise to preserve the aging immune system?11
An aging-related immune landscape in the hematopoietic immune system11
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