Immunity & Ageing

Papers
(The TQCC of Immunity & Ageing is 18. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-06-01 to 2026-06-01.)
ArticleCitations
Natural IgG antibodies to β amyloid are decreased in patients with Parkinson’s disease365
Cumulative physiological stress is associated with age-related changes to peripheral T lymphocyte subsets in healthy humans126
Review of evidence linking exposure to environmental stressors and associated alterations in the dynamics of immunosenescence (ISC) with the global increase in multiple sclerosis (MS)85
Pentraxin-3 and C-reactive protein plasma levels predict survival in older adults with or without metabolic syndrome – results of the PolSenior2 substudy81
The effects of high plasma levels of Aβ1-42 on mononuclear macrophage in mouse models of Alzheimer’s disease72
Transient immunostimulation with LPS promotes tissue repair in aged skin71
Influenza virus infection exacerbates gene expression related to neurocognitive dysfunction in brains of old mice69
Aging, inflammaging and immunosenescence as risk factors of severe COVID-1961
Fundamental and frontier research of immune responses to influenza vaccines in human aging: from cross-sectional and longitudinal studies to clinical trials and the geroscience perspective59
Different peripheral expression patterns of the nicotinic acetylcholine receptor in dementia with Lewy bodies and Alzheimer’s disease56
Vascular Cell Adhesion Molecule-1 (VCAM-1) contributes to macular fibrosis in neovascular age-related macular degeneration through modulating macrophage functions53
Differential associations of anti-cytomegalovirus antibodies and soluble CD14 levels with immunosenescence in people living with HIV on long term antiretroviral therapy48
Compositional analysis of lymphocytes and their relationship with health outcomes: findings from the health and retirement study46
Exploring the link between fat-soluble vitamins and aging-associated immune system status: a literature review45
Old hematopoietic stem cells retain competence to reconstitute a youthful B cell system that is highly responsive to protein-based vaccination45
Deciphering the impact of aging on splenic endothelial cell heterogeneity and immunosenescence through single-cell RNA sequencing analysis44
Obese plasma transfer accelerates cellular aging in the C57BL/6 mouse model44
TAOK3 limits age-associated inflammation by negatively modulating macrophage differentiation and their production of TNFα44
Immune cell phenotypes and mortality in the Framingham Heart Study42
Aging and the impact of global DNA methylation, telomere shortening, and total oxidative status on sarcopenia and frailty syndrome38
Association of adipose tissue inflammation and physical fitness in older adults36
Several areas of overlap between obesity and aging indicate obesity as a biomarker of accelerated aging of human B cell function and antibody responses36
Inhibition of the MEK/ERK pathway suppresses immune overactivation and mitigates TDP-43 toxicity in a Drosophila model of ALS35
The neutrophil to lymphocyte ratio associates with markers of Alzheimer’s disease pathology in cognitively unimpaired elderly people35
Chitosan alleviates ovarian aging by enhancing macrophage phagocyte-mediated tissue homeostasis34
The aging immune system and all-cause mortality in older americans: differences across sex and race/ethnicity33
Age-dependent immune profile in healthy individuals: an original study, systematic review and meta-analysis32
Systemic immune response in young and elderly patients after traumatic brain injury31
The use of alpha 1 thymosin as an immunomodulator of the response against SARS-Cov230
Targeting aging pathways with natural compounds: a review of curcumin, epigallocatechin gallate, thymoquinone, and resveratrol30
Characterisation of specific responses to three models of viral antigens in immunocompetent older adults29
The role of blood related inflammatory factors on age-related macular degeneration (AMD)29
Disrupted mitochondrial morphology and function exacerbate inflammation in elderly-onset ulcerative colitis28
High SARS-CoV-2 antibody levels after three consecutive BNT162b2 booster vaccine doses in nursing home residents28
Changes in the innate immune response to SARS-CoV-2 with advancing age in humans27
Advanced biological age is associated with improved antibody responses in older high-dose influenza vaccine recipients over four consecutive seasons26
Thymic function and survival at advance ages in nursing home residents from Southern Italy26
Respiratory virus immune response in the aged host26
Correction: Salutary effects of moderate but not high intensity aerobic exercise training on the frequency of peripheral T-cells associated with immunosenescence in older women at high risk of breast 26
Blood RNA-Seq profiling reveals a set of circular RNAs differentially expressed in frail individuals25
Temporal trends, sex differences, and age-related disease influence in Neutrophil, Lymphocyte count and Neutrophil to Lymphocyte-ratio: results from InCHIANTI follow-up study25
Ageing results in an exacerbated inflammatory response to LPS by resident lung cells25
Different phenotypes of microglia in animal models of Alzheimer disease24
Impaired function of Vγ9Vδ2 T cells in frail elderly23
Inflammatory markers and physical frailty: towards clinical application23
Exercise improves cognitive dysfunction and neuroinflammation in mice through Histone H3 lactylation in microglia23
Systemic inflammation as a central player in the initiation and development of Alzheimer’s disease23
Correction: Neo-epitopes emerging in the degenerative hippocampal granules of aged mice can be recognized by natural IgM auto-antibodies22
Adiponectin deficiency accelerates brain aging via mitochondria-associated neuroinflammation22
Obesity accelerates age defects in B cells, and weight loss improves B cell function22
Correction: The oldest unvaccinated Covid-19 survivors in South America22
Sex-specific innate immunity and ageing in long-lived fresh water turtles (Kinosternon flavescens: Kinosternidae)21
Melatonin enhances NK cell function in aged mice by increasing T-bet expression via the JAK3-STAT5 signaling pathway21
Immune cell signature in non-ischemic heart failure indicates chronic systemic immune activation with features of immunosenescence21
Crosstalk between adipogenesis and aging: role of polyphenols in combating adipogenic-associated aging21
Senescence-associated secretory phenotypes in mesenchymal cells contribute to cytotoxic immune response in oral lichen planus21
Attenuation of OX40 signaling suppression by age disrupts peripheral deletion of CD4+ T cells specific for the epidermal autoantigen desmoglein 320
Evaluation of T-cell aging-related immune phenotypes in the context of biological aging and multimorbidity in the Health and Retirement Study20
Toll-like receptor 4 (TLR4): new insight immune and aging20
Algorithms for appropriate patient stratification in the face of a new SARS-CoV-2 pandemic20
Aging and chronic inflammation: highlights from a multidisciplinary workshop20
A subset of gut leukocytes has telomerase-dependent “hyper-long” telomeres and require telomerase for function in zebrafish19
Secreted IgM deficiency alters the retinal landscape enhancing neurodegeneration associated with aging19
The reference ranges and characteristics of lymphocyte parameters and the correlation between lymphocyte parameters and routine health indicators in adults from China19
Ascorbic acid attenuates immunosenescence and cognitive decline via MYH9-Mediated CD8⁺ T cell differentiation19
Immune reconstitution efficacy and the risk factors of immune non-responsiveness after combined antiretroviral therapy in HIV-1 positive MSM and heterosexual population – a prospective cohort study19
Physical frailty in relation to immunosenescence involving pDC function in the Japanese elderly: a cross-sectional survey study19
Multiparity exacerbates Aβ accumulation and promotes cellular senescence in a mouse model of amyloidosis18
MicroRNAs: a crossroad that connects obesity to immunity and aging18
Immunogenicity of adjuvanted versus high-dose inactivated influenza vaccines in older adults: a randomized clinical trial18
Neutrophil-to-lymphocyte ratio as a sex-specific predictor of short-term mortality in hospitalised older adults with COVID-19: a pragmatic biomarker of inflammaging in acute vulnerability18
Targeting immunosenesence promotes clearance of senescent cells18
Heat-killed probiotic Levilactobacillus brevis MKAK9 and its exopolysaccharide promote longevity by modulating aging hallmarks and enhancing immune responses in Caenorhabditis elegans18
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