Journal of Neuroinflammation

Papers
(The TQCC of Journal of Neuroinflammation is 21. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-05-01 to 2025-05-01.)
ArticleCitations
Correction: Smek1 deficiency exacerbates experimental autoimmune encephalomyelitis by activating proinflammatory microglia and suppressing the IDO1-AhR pathway425
Fractalkine isoforms differentially regulate microglia-mediated inflammation and enhance visual function in the diabetic retina319
Regulation of the p75 neurotrophin receptor attenuates neuroinflammation and stimulates hippocampal neurogenesis in experimental Streptococcus pneumoniae meningitis296
Correction to: Vagus nerve stimulation modulates hippocampal inflammation caused by continuous stress in rats279
Intrauterine inflammation and postnatal intravenous dopamine alter the neurovascular unit in preterm newborn lambs239
Extracellular vesicles produced by HIV-1 Nef-expressing cells induce myelin impairment and oligodendrocyte damage in the mouse central nervous system196
Argonaute-2 protects the neurovascular unit from damage caused by systemic inflammation176
Inhibition of neutrophil extracellular traps alleviates blood–brain barrier disruption and cognitive dysfunction via Wnt3/β-catenin/TCF4 signaling in sepsis-associated encephalopathy166
HIF1α-dependent hypoxia response in myeloid cells requires IRE1α154
Zika virus infection of mature neurons from immunocompetent mice generates a disease-associated microglia and a tauopathy-like phenotype in link with a delayed interferon beta response153
Correction to: Pharmacologic activation of cholinergic alpha7 nicotinic receptors mitigates depressive-like behavior in a mouse model of chronic stress153
Carotid artery vascular stenosis causes the blood-CSF barrier damage and neuroinflammation149
IL-7Rα on CD4+ T cells is required for their survival and the pathogenesis of experimental autoimmune encephalomyelitis147
The deficient CLEC5A ameliorates the behavioral and pathological deficits via the microglial Aβ clearance in Alzheimer’s disease mouse model141
Preoperative gut microbiota of POCD patients induces pre- and postoperative cognitive impairment and systemic inflammation in rats137
Macrophage elastase (MMP12) critically contributes to the development of subretinal fibrosis128
The associations between plasma soluble Trem1 and neurological diseases: a Mendelian randomization study126
Maternal immunoglobulin G affects brain development of mouse offspring125
Integrin Mac1 mediates paraquat and maneb-induced learning and memory impairments in mice through NADPH oxidase–NLRP3 inflammasome axis-dependent microglial activation123
TPM1 mediates inflammation downstream of TREM2 via the PKA/CREB signaling pathway120
Flow cytometry identifies changes in peripheral and intrathecal lymphocyte patterns in CNS autoimmune disorders and primary CNS malignancies119
Brain gray matter astroglia-specific connexin 43 ablation attenuates spinal cord inflammatory demyelination117
Phosphatidate phosphatase Lipin1 alters mitochondria-associated endoplasmic reticulum membranes (MAMs) homeostasis: effects which contribute to the development of diabetic encephalopathy102
Citrobacter rodentium infection impairs dopamine metabolism and exacerbates the pathology of Parkinson’s disease in mice100
Therapeutic intervention in neuroinflammation for neovascular ocular diseases through targeting the cGAS-STING-necroptosis pathway91
Inhibition of histone deacetylase 6 alleviates neuropathic pain via direct regulating post-translation of spinal STAT3 and decreasing downstream C-C Motif Chemokine Ligand 7 synthesis90
Microglia-derived exosomes modulate myelin regeneration via miR-615-5p/MYRF axis89
Red nucleus IL-33 facilitates the early development of mononeuropathic pain in male rats by inducing TNF-α through activating ERK, p38 MAPK, and JAK2/STAT387
How the gut microbiota impacts neurodegenerative diseases by modulating CNS immune cells87
LXR agonism for CNS diseases: promises and challenges83
Selective neuronal expression of progranulin is sufficient to provide neuroprotective and anti-inflammatory effects after traumatic brain injury83
Stroke-induced immunosuppression: implications for the prevention and prediction of post-stroke infections80
Tregs dysfunction aggravates postoperative cognitive impairment in aged mice80
HMGB1 mediates synaptic loss and cognitive impairment in an animal model of sepsis-associated encephalopathy79
Exercise suppresses neuroinflammation for alleviating Alzheimer’s disease78
Marine fungal metabolite butyrolactone I prevents cognitive deficits by relieving inflammation and intestinal microbiota imbalance on aluminum trichloride-injured zebrafish78
Traumatic brain injury results in unique microglial and astrocyte transcriptomes enriched for type I interferon response77
Tryptophan-kynurenine metabolism: a link between the gut and brain for depression in inflammatory bowel disease76
Protein kinase B (AKT) upregulation and Thy-1-αvβ3 integrin-induced phosphorylation of Connexin43 by activated AKT in astrogliosis75
Exogenous monocyte myeloid-derived suppressor cells ameliorate immune imbalance, neuroinflammation and cognitive impairment in 5xFAD mice infected with Porphyromonas gingivalis75
α7 Nicotinic acetylcholine receptor: a key receptor in the cholinergic anti-inflammatory pathway exerting an antidepressant effect74
Injection of amyloid-β to lateral ventricle induces gut microbiota dysbiosis in association with inhibition of cholinergic anti-inflammatory pathways in Alzheimer’s disease74
Macrophage exosomal miR-30c-2-3p in atherosclerotic plaques aggravates microglial neuroinflammation during large-artery atherosclerotic stroke via TGF-β/SMAD2 pathway73
Intracranial VCAM1 at time of mechanical thrombectomy predicts ischemic stroke severity73
Immune response and pathogen invasion at the choroid plexus in the onset of cerebral toxoplasmosis73
Remibrutinib (LOU064) inhibits neuroinflammation driven by B cells and myeloid cells in preclinical models of multiple sclerosis72
Innate immune sensors and regulators at the blood brain barrier: focus on toll-like receptors and inflammasomes as mediators of neuro-immune crosstalk and inflammation72
MicroRNA-155-5p promotes neuroinflammation and central sensitization via inhibiting SIRT1 in a nitroglycerin-induced chronic migraine mouse model72
AIBP controls TLR4 inflammarafts and mitochondrial dysfunction in a mouse model of Alzheimer’s disease72
TLR4-dependent neuroinflammation mediates LPS-driven food-reward alterations during high-fat exposure71
Supporting the differential diagnosis of connective tissue diseases with neurological involvement by blood and cerebrospinal fluid flow cytometry70
Profiling the neuroimmune cascade in 3xTg-AD mice exposed to successive mild traumatic brain injuries70
H3K27me3 of Rnf19a promotes neuroinflammatory response during Japanese encephalitis virus infection70
Immunotherapy with an antibody against CD1d modulates neuroinflammation in an α-synuclein transgenic model of Lewy body like disease69
Single-cell RNA sequencing reveals peripheral blood leukocyte responses to spinal cord injury in mice with humanised immune systems69
Sequential treatment with a TNFR2 agonist and a TNFR1 antagonist improves outcomes in a humanized mouse model for MS69
Chronic rapid eye movement sleep deprivation aggravates the pathogenesis of Alzheimer’s disease by decreasing brain O-GlcNAc cycling in mice68
Deterioration of neuroimmune homeostasis in Alzheimer’s Disease patients who survive a COVID-19 infection68
NLRX1 limits inflammatory neurodegeneration in the anterior visual pathway67
Correction: Hydrogen sulfide-releasing cyclooxygenase inhibitor ATB-346 enhances motor function and reduces cortical lesion volume following traumatic brain injury in mice66
Inflammasomes at the crossroads of traumatic brain injury and post-traumatic epilepsy66
IDO1 modulates pain sensitivity and comorbid anxiety in chronic migraine through microglial activation and synaptic pruning66
Decoding Behcet’s Uveitis: an In-depth review of pathogenesis and therapeutic advances65
miR-19a/b-3p promotes inflammation during cerebral ischemia/reperfusion injury via SIRT1/FoxO3/SPHK1 pathway64
Compromised endothelial Wnt/β-catenin signaling mediates the blood-brain barrier disruption and leads to neuroinflammation in endotoxemia64
Nanoparticulate MgH2 ameliorates anxiety/depression-like behaviors in a mouse model of multiple sclerosis by regulating microglial polarization and oxidative stress63
Role of lipocalin-2 in surgery-induced cognitive decline in mice: a signal from neuron to microglia62
Long-term running exercise improves cognitive function and promotes microglial glucose metabolism and morphological plasticity in the hippocampus of APP/PS1 mice61
Hypochlorous acid derived from microglial myeloperoxidase could mediate high-mobility group box 1 release from neurons to amplify brain damage in cerebral ischemia–reperfusion injury60
Ubiquitination-mediated upregulation of glycolytic enzyme MCT4 in promoting astrocyte reactivity during neuroinflammation60
Distinguishing the effects of systemic CSF1R inhibition by PLX3397 on microglia and peripheral immune cells60
Nisin a probiotic bacteriocin mitigates brain microbiome dysbiosis and Alzheimer’s disease-like neuroinflammation triggered by periodontal disease60
Febrile temperature-regulated TRPV1 in CD4+ T cells mediates neuroinflammation in complex febrile seizures60
CSF sTREM2 in neurological diseases: a two-sample Mendelian randomization study59
The multifaceted role of vitreous hyalocytes: Orchestrating inflammation, angiomodulation and erythrophagocytosis in proliferative diabetic retinopathy59
The interaction between central and peripheral immune systems in methamphetamine use disorder: current status and future directions59
Complement inhibition targets a rich-club within the neuroinflammatory network after stroke to improve radiographic and functional outcomes59
Cladribine treatment improves cortical network functionality in a mouse model of autoimmune encephalomyelitis58
Human PMSCs-derived small extracellular vesicles alleviate neuropathic pain through miR-26a-5p/Wnt5a in SNI mice model58
Crosstalk between astrocytes and microglia results in increased degradation of α-synuclein and amyloid-β aggregates57
Interleukin-3 is associated with sTREM2 and mediates the correlation between amyloid-β and tau pathology in Alzheimer’s disease57
CXCR5 down-regulation alleviates cognitive dysfunction in a mouse model of sepsis-associated encephalopathy: potential role of microglial autophagy and the p38MAPK/NF-κB/STAT3 signaling pathway56
Extracellular vesicles from mesenchymal stem cells reduce neuroinflammation in hippocampus and restore cognitive function in hyperammonemic rats56
Dimethyl fumarate improves cognitive impairment and neuroinflammation in mice with Alzheimer’s disease55
GAS6 as a potential target to alleviate neuroinflammation during Japanese encephalitis in mouse models55
TRPV4 contributes to ER stress and inflammation: implications for Parkinson’s disease55
Mitochondrial DNA leakage: underlying mechanisms and therapeutic implications in neurological disorders55
Biologic TNF-α inhibitors reduce microgliosis, neuronal loss, and tau phosphorylation in a transgenic mouse model of tauopathy55
Hepcidin deficiency impairs hippocampal neurogenesis and mediates brain atrophy and memory decline in mice54
Inhibition of UTX/KDM6A improves recovery of spinal cord injury by attenuating BSCB permeability and macrophage infiltration through the MLCK/p-MLC pathway54
Tryptophan-rich diet and its effects on Htr7+ Tregs in alleviating neuroinflammation and cognitive impairment induced by lipopolysaccharide54
Brain transcriptome analysis of a CLN2 mouse model as a function of disease progression54
Prolactin deficiency drives diabetes-associated cognitive dysfunction by inducing microglia-mediated synaptic loss53
4-Ethylguaiacol modulates neuroinflammation and Th1/Th17 differentiation to ameliorate disease severity in experimental autoimmune encephalomyelitis53
Inflammatory monocytes and microglia play independent roles in inflammatory ictogenesis52
Appearance of claudin-5+ leukocyte subtypes in the blood and CNS during progression of EAE52
Absence of the lectin-like domain of thrombomodulin reduces HSV-1 lethality of mice with increased microglia responses52
Traumatic brain injury alters the effects of class II invariant peptide (CLIP) antagonism on chronic meningeal CLIP + B cells, neuropathology, and neurobehavioral impairment in 5xFAD mice52
Exploratory analysis of a Novel RACK1 mutation and its potential role in epileptic seizures via Microglia activation50
APOEε4 alters ApoE and Fabp7 in frontal cortex white matter in prodromal Alzheimer's disease50
Integration of National Health Insurance claims data and animal models reveals fexofenadine as a promising repurposed drug for Parkinson’s disease50
Satellite microglia: marker of traumatic brain injury and regulator of neuronal excitability50
Pericytes are protective in experimental pneumococcal meningitis through regulating leukocyte infiltration and blood–brain barrier function49
High-fat diet-induced diabetes leads to vascular alterations, pericyte reduction, and perivascular depletion of microglia in a 6-OHDA toxin model of Parkinson disease49
TYROBP/DAP12 knockout in Huntington’s disease Q175 mice cell-autonomously decreases microglial expression of disease-associated genes and non-cell-autonomously mitigates astrogliosis and motor deterio49
The BET PROTAC inhibitor dBET6 protects against retinal degeneration and inhibits the cGAS-STING in response to light damage48
Repurposing of epalrestat for neuroprotection in parkinson’s disease via activation of the KEAP1/Nrf2 pathway48
Annexin A1 protects against cerebral ischemia–reperfusion injury by modulating microglia/macrophage polarization via FPR2/ALX-dependent AMPK-mTOR pathway48
Rifaximin-mediated gut microbiota regulation modulates the function of microglia and protects against CUMS-induced depression-like behaviors in adolescent rat48
Morinda officinalis oligosaccharides mitigate depression-like behaviors in hypertension rats by regulating Mfn2-mediated mitophagy48
Fenebrutinib, a Bruton’s tyrosine kinase inhibitor, blocks distinct human microglial signaling pathways47
Astrocytic stress response is induced by exposure to astrocyte-binding antibodies expressed by plasmablasts from pediatric patients with acute transverse myelitis47
Soluble CD27 is an intrathecal biomarker of T-cell-mediated lesion activity in multiple sclerosis47
The insular cortex is not insular in thyroid eye disease: neuroimaging revelations of central–peripheral system interaction47
Sex differences and similarities in the neuroimmune response to central administration of poly I:C46
Microglial–oligodendrocyte interactions in myelination and neurological function recovery after traumatic brain injury46
Asrij/OCIAD1 depletion reduces inflammatory microglial activation and ameliorates Aβ pathology in an Alzheimer’s disease mouse model46
Prostaglandin EP2 receptor antagonist ameliorates neuroinflammation in a two-hit mouse model of Alzheimer’s disease46
Therapeutic reduction of neurocan in murine intracerebral hemorrhage lesions promotes oligodendrogenesis and functional recovery46
Transient post-operative overexpression of CXCR2 on monocytes of traumatic brain injury patients drives monocyte chemotaxis toward cerebrospinal fluid and enhances monocyte-mediated immunogenic cell d46
Retraction Note to: Regulation of autophagy by the nuclear factor κB signaling pathway in the hippocampus of rats with sepsis45
Neuroprotective effects of GSK-343 in an in vivo model of MPTP-induced nigrostriatal degeneration45
Cinnamaldehyde and its combination with deferoxamine ameliorate inflammation, ferroptosis and hematoma expansion after intracerebral hemorrhage in mice44
Neuroinflammatory transcriptional programs induced in rhesus pre-frontal cortex white matter during acute SHIV infection44
Calcitonin gene-related peptide regulates spinal microglial activation through the histone H3 lysine 27 trimethylation via enhancer of zeste homolog-2 in rats with neuropathic pain44
25-Hydroxycholesterol modulates microglial function and exacerbates Alzheimer’s disease pathology: mechanistic insights and therapeutic potential of cholesterol esterification inhibition44
Proteomic profiling identifies novel inflammation-related plasma proteins associated with ischemic stroke outcome44
Impact of disease-modifying therapy on dendritic cells and exploring their immunotherapeutic potential in multiple sclerosis43
Transfer of patient’s peripheral blood mononuclear cells (PBMCs) disrupts blood–brain barrier and induces anti-NMDAR encephalitis: a study of novel humanized PBMC mouse model43
Upregulation of TRPC5 in hippocampal excitatory synapses improves memory impairment associated with neuroinflammation in microglia knockout IL-10 mice42
Inflammasome inhibition protects dopaminergic neurons from α-synuclein pathology in a model of progressive Parkinson’s disease42
SRGN amplifies microglia-mediated neuroinflammation and exacerbates ischemic brain injury41
Mild-to-severe traumatic brain injury in children: altered cytokines reflect severity41
Ogt-mediated O-GlcNAcylation inhibits astrocytes activation through modulating NF-κB signaling pathway41
Extended interval dosing of ocrelizumab modifies the repopulation of B cells without altering the clinical efficacy in multiple sclerosis40
Noninvasive ultrasound stimulation to treat myocarditis through splenic neuro-immune regulation40
The glucocorticoid receptor as a master regulator of the Müller cell response to diabetic conditions in mice40
Single-cell RNA sequencing reveals a landscape and targeted treatment of ferroptosis in retinal ischemia/reperfusion injury40
An AGS-associated mutation in ADAR1 catalytic domain results in early-onset and MDA5-dependent encephalopathy with IFN pathway activation in the brain40
Elevated lipoprotein(a) and lipoprotein-associated phospholipase A2 are associated with unfavorable functional outcomes in patients with ischemic stroke40
Hydroxychloroquine attenuates neuroinflammation following traumatic brain injury by regulating the TLR4/NF-κB signaling pathway40
[18F]F-DED PET imaging of reactive astrogliosis in neurodegenerative diseases: preclinical proof of concept and first-in-human data40
Targeting neuroinflammation as a preventive and therapeutic approach for perioperative neurocognitive disorders39
Group 2 innate lymphoid cells are numerically and functionally deficient in the triple transgenic mouse model of Alzheimer’s disease39
Serum GFAP and NfL as disease severity and prognostic biomarkers in patients with aquaporin-4 antibody-positive neuromyelitis optica spectrum disorder39
Ethanol-activated microglial exosomes induce MCP1 signaling mediated death of stress-regulatory proopiomelanocortin neurons in the developing hypothalamus39
25-hydroxycholesterol promotes brain cytokine production and leukocyte infiltration in a mouse model of lipopolysaccharide-induced neuroinflammation38
Sitagliptin eye drops prevent the impairment of retinal neurovascular unit in the new Trpv2+/− rat model38
Transcriptomic analysis unveils bona fide molecular signatures of microglia under conditions of homeostasis and viral encephalitis38
Central activation of the fatty acid sensor GPR120 suppresses microglia reactivity and alleviates sickness- and anxiety-like behaviors38
Fidgetin-like 2 knockdown increases acute neuroinflammation and improves recovery in a rat model of spinal cord injury38
Supraphysiologic doses of 17β-estradiol aggravate depression-like behaviors in ovariectomized mice possibly via regulating microglial responses and brain glycerophospholipid metabolism38
Impairment of neuronal tyrosine phosphatase STEP worsens post-ischemic inflammation and brain injury under hypertensive condition38
Temporal changes in regulatory T cell subsets defined by the transcription factor Helios in stroke and their potential role in stroke-associated infection: a prospective case–control study38
PARP9 exacerbates apoptosis and neuroinflammation via the PI3K pathway in the thalamus and hippocampus and cognitive decline after cortical infarction38
MAVS signaling shapes microglia responses to neurotropic virus infection38
The contribution of the meningeal immune interface to neuroinflammation in traumatic brain injury38
Lowering blood cholesterol does not affect neuroinflammation in experimental autoimmune encephalomyelitis38
Effects of diabetes on microglial physiology: a systematic review of in vitro, preclinical and clinical studies38
RhANP attenuates endotoxin-derived cognitive dysfunction through subdiaphragmatic vagus nerve-mediated gut microbiota–brain axis38
Aicardi-Goutières syndrome-associated mutation at ADAR1 gene locus activates innate immune response in mouse brain37
Erythrocyte–brain endothelial interactions induce microglial responses and cerebral microhemorrhages in vivo37
Soluble TREM2 is associated with death and cardiovascular events after acute ischemic stroke: an observational study from CATIS37
Impaired response of blood neutrophils to cell-death stimulus differentiates AQP4-IgG-seropositive NMOSD from MOGAD37
Administration of Maresin-1 ameliorates the physiopathology of experimental autoimmune encephalomyelitis37
IL-10 production by granulocytes promotes Staphylococcus aureus craniotomy infection37
Transcriptome alterations in peripheral blood B cells of patients with multiple sclerosis receiving immune reconstitution therapy37
Neuroimmune multi-hit perspective of coronaviral infection37
Type I/type III IFN and related factors regulate JEV infection and BBB endothelial integrity37
Interleukin-6 actions in the hypothalamus protects against obesity and is involved in the regulation of neurogenesis36
Intermittent theta-burst stimulation improves motor function by inhibiting neuronal pyroptosis and regulating microglial polarization via TLR4/NFκB/NLRP3 signaling pathway in cerebral ischemic mice36
Neuroinflammation, memory, and depression: new approaches to hippocampal neurogenesis36
Cyanidin-3-O-glucoside protects the brain and improves cognitive function in APPswe/PS1ΔE9 transgenic mice model36
Homer1 promotes the conversion of A1 astrocytes to A2 astrocytes and improves the recovery of transgenic mice after intracerebral hemorrhage36
Reduced microglia activation following metformin administration or microglia ablation is sufficient to prevent functional deficits in a mouse model of neonatal stroke36
TAK1 mediates neuronal pyroptosis in early brain injury after subarachnoid hemorrhage35
High-parameter cytometry unmasks microglial cell spatio-temporal response kinetics in severe neuroinflammatory disease35
TRPV4-induced Müller cell gliosis and TNF-α elevation-mediated retinal ganglion cell apoptosis in glaucomatous rats via JAK2/STAT3/NF-κB pathway35
Role of SPAK–NKCC1 signaling cascade in the choroid plexus blood–CSF barrier damage after stroke35
Inhibition of discoidin domain receptor (DDR)-1 with nilotinib alters CSF miRNAs and is associated with reduced inflammation and vascular fibrosis in Alzheimer’s disease34
Impact of noradrenergic inhibition on neuroinflammation and pathophysiology in mouse models of Alzheimer’s disease34
Microglia sustain anterior cingulate cortex neuronal hyperactivity in nicotine-induced pain34
Deletion of CD47 from Schwann cells and macrophages hastens myelin disruption/dismantling and scavenging in Schwann cells and augments myelin debris phagocytosis in macrophages34
Neuroimmune proteins can differentiate between tauopathies34
Morphine-induced microglial immunosuppression via activation of insufficient mitophagy regulated by NLRX134
The novel HS-mimetic, Tet-29, regulates immune cell trafficking across barriers of the CNS during inflammation34
Correction to: Cathepsin C promotes microglia M1 polarization and aggravates neuroinflammation via activation of Ca2+-dependent PKC/p38MAPK/NF-κB pathway34
Microglia and Immune cells interactions in multiple sclerosis cognitive impairment: a postmortem study34
Role of myeloid cells in ischemic retinopathies: recent advances and unanswered questions34
P2X7 receptor antagonists modulate experimental autoimmune neuritis via regulation of NLRP3 inflammasome activation and Th17 and Th1 cell differentiation33
Global gene expression and chromatin accessibility of the peripheral nervous system in animal models of persistent pain33
Moss-derived human complement factor H modulates retinal immune response and attenuates retinal degeneration33
Integrated single-cell transcriptomics of cerebrospinal fluid cells in treatment-naïve multiple sclerosis33
Longitudinal cerebrospinal fluid measurements show glial hypo- and hyperactivation in predementia Alzheimer’s disease33
Western diet increases brain metabolism and adaptive immune responses in a mouse model of amyloidosis33
Interleukin-6 deficiency reduces neuroinflammation by inhibiting the STAT3-cGAS-STING pathway in Alzheimer’s disease mice32
Interleukin-9 protects from microglia- and TNF-mediated synaptotoxicity in experimental multiple sclerosis32
Systemic inflammation alters the neuroinflammatory response: a prospective clinical trial in traumatic brain injury32
Repeated LPS induces training and tolerance of microglial responses across brain regions32
Ambient RNAs removal of cortex-specific snRNA-seq reveals Apoe+ microglia/macrophage after deeper cerebral hypoperfusion in mice32
Phthalide derivative CD21 attenuates tissue plasminogen activator-induced hemorrhagic transformation in ischemic stroke by enhancing macrophage scavenger receptor 1-mediated DAMP (peroxiredoxin 1) cle32
Neurofilament light: a possible prognostic biomarker for treatment of vascular contributions to cognitive impairment and dementia32
Fatty acids role in multiple sclerosis as “metabokines”32
Models of microglia depletion and replenishment elicit protective effects to alleviate vascular and neuronal damage in the diabetic murine retina32
N-acetylglucosamine inhibits inflammation and neurodegeneration markers in multiple sclerosis: a mechanistic trial32
HMGB1 mediates cognitive impairment caused by the NLRP3 inflammasome in the late stage of traumatic brain injury32
Fascin-1 limits myosin activity in microglia to control mechanical characterization of the injured spinal cord32
NAD+ improves cognitive function and reduces neuroinflammation by ameliorating mitochondrial damage and decreasing ROS production in chronic cerebral hypoperfusion models through Sirt1/PGC-1α pathway31
Acute postnatal inflammation alters adult microglial responses to LPS that are sex-, region- and timing of postnatal inflammation-dependent31
Activation of GPR40 attenuates neuroinflammation and improves neurological function via PAK4/CREB/KDM6B pathway in an experimental GMH rat model31
Divanillyl sulfone suppresses NLRP3 inflammasome activation via inducing mitophagy to ameliorate chronic neuropathic pain in mice31
Inhibition of NADPH oxidase 2 enhances resistance to viral neuroinflammation by facilitating M1-polarization of macrophages at the extraneural tissues31
Up-regulated succinylation modifications induce a senescence phenotype in microglia by altering mitochondrial energy metabolism31
Differential contribution of THIK-1 K+ channels and P2X7 receptors to ATP-mediated neuroinflammation by human microglia31
Perivascular macrophages in high-fat diet-induced hypothalamic inflammation31
Hippocampal microRNA-26a-3p deficit contributes to neuroinflammation and behavioral disorders via p38 MAPK signaling pathway in rats30
Synergistic effects of repeated transcranial magnetic stimulation and mesenchymal stem cells transplantation on alleviating neuroinflammation and PANoptosis in cerebral ischemia30
Innate immune stimulation by monophosphoryl lipid A prevents chronic social defeat stress-induced anxiety-like behaviors in mice30
SPOCK2 modulates neuropathic pain by interacting with MT1-MMP to regulate astrocytic MMP-2 activation in rats with chronic constriction injury30
Aberrant copper metabolism and hepatic inflammation cause neurological manifestations in a mouse model of Wilson’s disease30
1α,25-dihydroxyvitamin D3 protects retinal ganglion cells in glaucomatous mice30
Distinct features of B cell receptors in neuromyelitis optica spectrum disorder among CNS inflammatory demyelinating diseases29
Glyceryl triacetate promotes blood–brain barrier recovery after ischemic stroke through lipogenesis-mediated IL-33 in mice29
Astroglial modulation of synaptic function in the non-demyelinated cerebellar cortex is dependent on MyD88 signaling in a model of toxic demyelination29
The interaction of tPA with NMDAR1 drives neuroinflammation and neurodegeneration in α-synuclein-mediated neurotoxicity29
Biomass smoke inhalation promotes neuroinflammatory and metabolomic temporal changes in the hippocampus of female mice29
H3K18 lactylation-mediated nucleotide-binding oligomerization domain-2 (NOD2) expression promotes bilirubin-induced pyroptosis of astrocytes29
Growth differentiation factor 15 aggravates sepsis-induced cognitive and memory impairments by promoting microglial inflammatory responses and phagocytosis29
Japanese encephalitis virus-induced DNA methylation contributes to blood-brain barrier permeability by modulating tight junction protein expression28
Endothelial glycocalyx in traumatic brain injury associated coagulopathy: potential mechanisms and impact28
Autophagy protein NRBF2 attenuates endoplasmic reticulum stress-associated neuroinflammation and oxidative stress via promoting autophagosome maturation by interacting with Rab7 after SAH28
Neuroimmune modulation in liver pathophysiology28
Mitochondrial protective effects caused by the administration of mefenamic acid in sepsis28
Mas receptor activation facilitates innate hematoma resolution and neurological recovery after hemorrhagic stroke in mice28
Extracellular vesicles derived from mesenchymal stem cells alleviate neuroinflammation and mechanical allodynia in interstitial cystitis rats by inhibiting NLRP3 inflammasome activation28
Molecular mimicry of NMDA receptors may contribute to neuropsychiatric symptoms in severe COVID-19 cases28
Oxygen therapy attenuates neuroinflammation after spinal cord injury28
The role of CD56bright NK cells in neurodegenerative disorders28
Anti-inflammatory role of GM1 and other gangliosides on microglia28
Systemic inflammatory markers of persistent cerebral edema after aneurysmal subarachnoid hemorrhage28
Fucoidan reduces NET accumulation and alleviates chemotherapy-induced peripheral neuropathy via the gut–blood–DRG axis27
Astrocytic CXCL5 hinders microglial phagocytosis of myelin debris and aggravates white matter injury in chronic cerebral ischemia27
Connexin 43 gap junction-mediated astrocytic network reconstruction attenuates isoflurane-induced cognitive dysfunction in mice27
Single cell RNA sequencing after moderate traumatic brain injury: effects of therapeutic hypothermia27
Using zebrafish to understand reciprocal interactions between the nervous and immune systems and the microbial world27
Interleukin-2 improves insulin sensitivity through hypothalamic sympathetic activation in obese mice27
Synaptic loss and progression in mice infected with Angiostrongylus cantonensis in the early stage27
High-fat diet exacerbates cognitive decline in mouse models of Alzheimer's disease and mixed dementia in a sex-dependent manner27
The protective PLCγ2-P522R variant mitigates Alzheimer’s disease-associated pathologies by enhancing beneficial microglial functions27
AMPK-autophagy-mediated inhibition of microRNA-30a-5p alleviates morphine tolerance via SOCS3-dependent neuroinflammation suppression27
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