Journal of Neuroinflammation

Papers
(The TQCC of Journal of Neuroinflammation is 24. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-12-01 to 2025-12-01.)
ArticleCitations
Intrauterine inflammation and postnatal intravenous dopamine alter the neurovascular unit in preterm newborn lambs437
Correction: Smek1 deficiency exacerbates experimental autoimmune encephalomyelitis by activating proinflammatory microglia and suppressing the IDO1-AhR pathway403
Correction to: Vagus nerve stimulation modulates hippocampal inflammation caused by continuous stress in rats390
Correction to: Pharmacologic activation of cholinergic alpha7 nicotinic receptors mitigates depressive-like behavior in a mouse model of chronic stress379
SARS-CoV-2 spike triggers TLR7-dependent endolysosome dysfunction and senescence in human astrocytes291
Inflammation in Neuronal Intranuclear Inclusion Disease (NIID): mechanisms, biomarkers, and therapeutic implications240
Maternal immunoglobulin G affects brain development of mouse offspring204
Extracellular vesicles produced by HIV-1 Nef-expressing cells induce myelin impairment and oligodendrocyte damage in the mouse central nervous system197
Argonaute-2 protects the neurovascular unit from damage caused by systemic inflammation183
Protein kinase B (AKT) upregulation and Thy-1-αvβ3 integrin-induced phosphorylation of Connexin43 by activated AKT in astrogliosis157
Flow cytometry identifies changes in peripheral and intrathecal lymphocyte patterns in CNS autoimmune disorders and primary CNS malignancies157
Marine fungal metabolite butyrolactone I prevents cognitive deficits by relieving inflammation and intestinal microbiota imbalance on aluminum trichloride-injured zebrafish151
Phosphatidate phosphatase Lipin1 alters mitochondria-associated endoplasmic reticulum membranes (MAMs) homeostasis: effects which contribute to the development of diabetic encephalopathy148
IL-7Rα on CD4+ T cells is required for their survival and the pathogenesis of experimental autoimmune encephalomyelitis144
Therapeutic intervention in neuroinflammation for neovascular ocular diseases through targeting the cGAS-STING-necroptosis pathway133
Inhibition of histone deacetylase 6 alleviates neuropathic pain via direct regulating post-translation of spinal STAT3 and decreasing downstream C-C Motif Chemokine Ligand 7 synthesis127
The deficient CLEC5A ameliorates the behavioral and pathological deficits via the microglial Aβ clearance in Alzheimer’s disease mouse model119
HIF1α-dependent hypoxia response in myeloid cells requires IRE1α113
Integrin Mac1 mediates paraquat and maneb-induced learning and memory impairments in mice through NADPH oxidase–NLRP3 inflammasome axis-dependent microglial activation110
Carotid artery vascular stenosis causes the blood-CSF barrier damage and neuroinflammation108
Zika virus infection of mature neurons from immunocompetent mice generates a disease-associated microglia and a tauopathy-like phenotype in link with a delayed interferon beta response108
Citrobacter rodentium infection impairs dopamine metabolism and exacerbates the pathology of Parkinson’s disease in mice107
Microglia-derived exosomes modulate myelin regeneration via miR-615-5p/MYRF axis100
Selective neuronal expression of progranulin is sufficient to provide neuroprotective and anti-inflammatory effects after traumatic brain injury100
Macrophage elastase (MMP12) critically contributes to the development of subretinal fibrosis99
TPM1 mediates inflammation downstream of TREM2 via the PKA/CREB signaling pathway99
Gut microbiota and their influence in brain cancer milieu98
The associations between plasma soluble Trem1 and neurological diseases: a Mendelian randomization study97
Fractalkine isoforms differentially regulate microglia-mediated inflammation and enhance visual function in the diabetic retina97
How the gut microbiota impacts neurodegenerative diseases by modulating CNS immune cells95
Preoperative gut microbiota of POCD patients induces pre- and postoperative cognitive impairment and systemic inflammation in rats95
Tregs dysfunction aggravates postoperative cognitive impairment in aged mice94
LXR agonism for CNS diseases: promises and challenges94
HMGB1 mediates synaptic loss and cognitive impairment in an animal model of sepsis-associated encephalopathy93
Exercise suppresses neuroinflammation for alleviating Alzheimer’s disease93
Elucidating the specific mechanisms of the gut-brain axis: the short-chain fatty acids-microglia pathway93
Inhibition of neutrophil extracellular traps alleviates blood–brain barrier disruption and cognitive dysfunction via Wnt3/β-catenin/TCF4 signaling in sepsis-associated encephalopathy92
Ubiquitination-mediated upregulation of glycolytic enzyme MCT4 in promoting astrocyte reactivity during neuroinflammation91
Biomarkers of progressive multiple sclerosis decrease following autologous hematopoietic stem cell transplantation90
Supporting the differential diagnosis of connective tissue diseases with neurological involvement by blood and cerebrospinal fluid flow cytometry88
NLRX1 limits inflammatory neurodegeneration in the anterior visual pathway88
Immunotherapy with an antibody against CD1d modulates neuroinflammation in an α-synuclein transgenic model of Lewy body like disease87
Profiling the neuroimmune cascade in 3xTg-AD mice exposed to successive mild traumatic brain injuries86
Inflammasomes at the crossroads of traumatic brain injury and post-traumatic epilepsy85
Correction: Hydrogen sulfide-releasing cyclooxygenase inhibitor ATB-346 enhances motor function and reduces cortical lesion volume following traumatic brain injury in mice85
CRTH2 is critical for IL-1β-producing B cells during experimental autoimmune encephalomyelitis in mice via p38 signaling84
Cardiac arrest triggers IL-17-mediated neuroinflammation and astrocyte polarization: insights into pathogenesis and intervention82
Single-cell RNA sequencing reveals peripheral blood leukocyte responses to spinal cord injury in mice with humanised immune systems82
Exogenous monocyte myeloid-derived suppressor cells ameliorate immune imbalance, neuroinflammation and cognitive impairment in 5xFAD mice infected with Porphyromonas gingivalis80
α7 Nicotinic acetylcholine receptor: a key receptor in the cholinergic anti-inflammatory pathway exerting an antidepressant effect79
Role of lipocalin-2 in surgery-induced cognitive decline in mice: a signal from neuron to microglia78
Macrophage exosomal miR-30c-2-3p in atherosclerotic plaques aggravates microglial neuroinflammation during large-artery atherosclerotic stroke via TGF-β/SMAD2 pathway77
Sequential treatment with a TNFR2 agonist and a TNFR1 antagonist improves outcomes in a humanized mouse model for MS76
Compromised endothelial Wnt/β-catenin signaling mediates the blood-brain barrier disruption and leads to neuroinflammation in endotoxemia76
Innate immune sensors and regulators at the blood brain barrier: focus on toll-like receptors and inflammasomes as mediators of neuro-immune crosstalk and inflammation76
Deterioration of neuroimmune homeostasis in Alzheimer’s Disease patients who survive a COVID-19 infection75
Single−cell transcriptomic landscape of sciatic nerve after transection injury75
Immune response and pathogen invasion at the choroid plexus in the onset of cerebral toxoplasmosis75
H3K27me3 of Rnf19a promotes neuroinflammatory response during Japanese encephalitis virus infection74
Injection of amyloid-β to lateral ventricle induces gut microbiota dysbiosis in association with inhibition of cholinergic anti-inflammatory pathways in Alzheimer’s disease73
Distinguishing the effects of systemic CSF1R inhibition by PLX3397 on microglia and peripheral immune cells73
A systematic review of the causes and consequences of spreading depolarization in neuroinflammation; implications for neurovascular disorders71
MicroRNA-155-5p promotes neuroinflammation and central sensitization via inhibiting SIRT1 in a nitroglycerin-induced chronic migraine mouse model70
Long-term running exercise improves cognitive function and promotes microglial glucose metabolism and morphological plasticity in the hippocampus of APP/PS1 mice69
Remibrutinib (LOU064) inhibits neuroinflammation driven by B cells and myeloid cells in preclinical models of multiple sclerosis69
AIBP controls TLR4 inflammarafts and mitochondrial dysfunction in a mouse model of Alzheimer’s disease68
Nanoparticulate MgH2 ameliorates anxiety/depression-like behaviors in a mouse model of multiple sclerosis by regulating microglial polarization and oxidative stress67
Diffuse traumatic brain injury induced stimulator of interferons (STING) signaling in microglia drives cortical neuroinflammation, neuronal dysfunction, and impaired cognition67
IDO1 modulates pain sensitivity and comorbid anxiety in chronic migraine through microglial activation and synaptic pruning66
Chronic rapid eye movement sleep deprivation aggravates the pathogenesis of Alzheimer’s disease by decreasing brain O-GlcNAc cycling in mice64
Decoding Behcet’s Uveitis: an In-depth review of pathogenesis and therapeutic advances64
TLR4-dependent neuroinflammation mediates LPS-driven food-reward alterations during high-fat exposure64
Salt-sensitive hypertension promotes neuronal mitochondrial stress and neurodegenerative alterations via neuro-vascular metabolic reprogramming and local RAS signaling63
Sex differences on laser-induced choroidal neovascularization and short-chain fatty acid treatment in a mouse model63
Neuro-immune regulation of sepsis-associated delirium via the PBN-CeA-spleen axis63
Hypochlorous acid derived from microglial myeloperoxidase could mediate high-mobility group box 1 release from neurons to amplify brain damage in cerebral ischemia–reperfusion injury63
Traumatic brain injury alters the effects of class II invariant peptide (CLIP) antagonism on chronic meningeal CLIP + B cells, neuropathology, and neurobehavioral impairment in 5xFAD mice63
Nisin a probiotic bacteriocin mitigates brain microbiome dysbiosis and Alzheimer’s disease-like neuroinflammation triggered by periodontal disease63
Exploratory analysis of a Novel RACK1 mutation and its potential role in epileptic seizures via Microglia activation62
GAS6 as a potential target to alleviate neuroinflammation during Japanese encephalitis in mouse models62
Spatiotemporal dynamic changes of meningeal microenvironment influence meningeal lymphatic function following subarachnoid hemorrhage: from inflammatory response to tissue remodeling60
Cladribine treatment improves cortical network functionality in a mouse model of autoimmune encephalomyelitis60
Absence of the lectin-like domain of thrombomodulin reduces HSV-1 lethality of mice with increased microglia responses60
The BET PROTAC inhibitor dBET6 protects against retinal degeneration and inhibits the cGAS-STING in response to light damage59
TRPV4 contributes to ER stress and inflammation: implications for Parkinson’s disease59
APOEε4 alters ApoE and Fabp7 in frontal cortex white matter in prodromal Alzheimer's disease58
Repurposing of epalrestat for neuroprotection in parkinson’s disease via activation of the KEAP1/Nrf2 pathway58
Interleukin-3 is associated with sTREM2 and mediates the correlation between amyloid-β and tau pathology in Alzheimer’s disease58
Tryptophan-rich diet and its effects on Htr7+ Tregs in alleviating neuroinflammation and cognitive impairment induced by lipopolysaccharide58
Complement inhibition targets a rich-club within the neuroinflammatory network after stroke to improve radiographic and functional outcomes58
Biologic TNF-α inhibitors reduce microgliosis, neuronal loss, and tau phosphorylation in a transgenic mouse model of tauopathy57
Inhibition of UTX/KDM6A improves recovery of spinal cord injury by attenuating BSCB permeability and macrophage infiltration through the MLCK/p-MLC pathway57
Human PMSCs-derived small extracellular vesicles alleviate neuropathic pain through miR-26a-5p/Wnt5a in SNI mice model56
Integration of National Health Insurance claims data and animal models reveals fexofenadine as a promising repurposed drug for Parkinson’s disease56
Pericytes are protective in experimental pneumococcal meningitis through regulating leukocyte infiltration and blood–brain barrier function55
Febrile temperature-regulated TRPV1 in CD4+ T cells mediates neuroinflammation in complex febrile seizures55
Extracellular vesicles from mesenchymal stem cells reduce neuroinflammation in hippocampus and restore cognitive function in hyperammonemic rats55
Sex-associated and disease state-dependent monocyte polarization and CNS-trafficking phenotypes in pediatric acute-onset neuropsychiatric syndrome (PANS)55
Satellite microglia: marker of traumatic brain injury and regulator of neuronal excitability54
Prolactin deficiency drives diabetes-associated cognitive dysfunction by inducing microglia-mediated synaptic loss54
TYROBP/DAP12 knockout in Huntington’s disease Q175 mice cell-autonomously decreases microglial expression of disease-associated genes and non-cell-autonomously mitigates astrogliosis and motor deterio54
Appearance of claudin-5+ leukocyte subtypes in the blood and CNS during progression of EAE54
Hepcidin deficiency impairs hippocampal neurogenesis and mediates brain atrophy and memory decline in mice53
Brd4 expression in CD4 T cells and in microglia promotes neuroinflammation in experimental autoimmune encephalomyelitis53
The interaction between central and peripheral immune systems in methamphetamine use disorder: current status and future directions52
The multifaceted role of vitreous hyalocytes: Orchestrating inflammation, angiomodulation and erythrophagocytosis in proliferative diabetic retinopathy52
Inflammatory monocytes and microglia play independent roles in inflammatory ictogenesis52
CSF sTREM2 in neurological diseases: a two-sample Mendelian randomization study52
Nanozymes in neuropathic pain: strategies bridging oxidative stress, mitochondrial repair, and neuroimmune modulation for targeted therapy51
Mitochondrial DNA leakage: underlying mechanisms and therapeutic implications in neurological disorders50
Morinda officinalis oligosaccharides mitigate depression-like behaviors in hypertension rats by regulating Mfn2-mediated mitophagy50
Astrocytic stress response is induced by exposure to astrocyte-binding antibodies expressed by plasmablasts from pediatric patients with acute transverse myelitis49
Retraction Note to: Regulation of autophagy by the nuclear factor κB signaling pathway in the hippocampus of rats with sepsis49
Dimethyl fumarate improves cognitive impairment and neuroinflammation in mice with Alzheimer’s disease49
Ogt-mediated O-GlcNAcylation inhibits astrocytes activation through modulating NF-κB signaling pathway48
[18F]F-DED PET imaging of reactive astrogliosis in neurodegenerative diseases: preclinical proof of concept and first-in-human data47
Microglial–oligodendrocyte interactions in myelination and neurological function recovery after traumatic brain injury47
The glucocorticoid receptor as a master regulator of the Müller cell response to diabetic conditions in mice46
Mild-to-severe traumatic brain injury in children: altered cytokines reflect severity46
The insular cortex is not insular in thyroid eye disease: neuroimaging revelations of central–peripheral system interaction46
Fenebrutinib, a Bruton’s tyrosine kinase inhibitor, blocks distinct human microglial signaling pathways46
25-Hydroxycholesterol modulates microglial function and exacerbates Alzheimer’s disease pathology: mechanistic insights and therapeutic potential of cholesterol esterification inhibition46
Single-cell RNA sequencing reveals a landscape and targeted treatment of ferroptosis in retinal ischemia/reperfusion injury45
Proteomic profiling identifies novel inflammation-related plasma proteins associated with ischemic stroke outcome45
SRGN amplifies microglia-mediated neuroinflammation and exacerbates ischemic brain injury45
An AGS-associated mutation in ADAR1 catalytic domain results in early-onset and MDA5-dependent encephalopathy with IFN pathway activation in the brain45
Retraction Note: Stimulator of IFN genes mediates neuroinflammatory injury by suppressing AMPK signal in experimental subarachnoid hemorrhage44
Transfer of patient’s peripheral blood mononuclear cells (PBMCs) disrupts blood–brain barrier and induces anti-NMDAR encephalitis: a study of novel humanized PBMC mouse model44
Elevated lipoprotein(a) and lipoprotein-associated phospholipase A2 are associated with unfavorable functional outcomes in patients with ischemic stroke44
Neuroprotective effects of GSK-343 in an in vivo model of MPTP-induced nigrostriatal degeneration44
Therapeutic reduction of neurocan in murine intracerebral hemorrhage lesions promotes oligodendrogenesis and functional recovery44
Extended interval dosing of ocrelizumab modifies the repopulation of B cells without altering the clinical efficacy in multiple sclerosis43
Impact of disease-modifying therapy on dendritic cells and exploring their immunotherapeutic potential in multiple sclerosis43
Neuroinflammatory transcriptional programs induced in rhesus pre-frontal cortex white matter during acute SHIV infection43
Soluble CD27 is an intrathecal biomarker of T-cell-mediated lesion activity in multiple sclerosis42
Cinnamaldehyde and its combination with deferoxamine ameliorate inflammation, ferroptosis and hematoma expansion after intracerebral hemorrhage in mice42
Noninvasive ultrasound stimulation to treat myocarditis through splenic neuro-immune regulation42
Inflammasome inhibition protects dopaminergic neurons from α-synuclein pathology in a model of progressive Parkinson’s disease42
Temporal changes in regulatory T cell subsets defined by the transcription factor Helios in stroke and their potential role in stroke-associated infection: a prospective case–control study41
Modular inflammation network discovery from large-scale phenotypic screening in genetically heterogeneous mouse brains41
Fidgetin-like 2 knockdown increases acute neuroinflammation and improves recovery in a rat model of spinal cord injury41
Asrij/OCIAD1 depletion reduces inflammatory microglial activation and ameliorates Aβ pathology in an Alzheimer’s disease mouse model41
Transient post-operative overexpression of CXCR2 on monocytes of traumatic brain injury patients drives monocyte chemotaxis toward cerebrospinal fluid and enhances monocyte-mediated immunogenic cell d41
IL-10 production by granulocytes promotes Staphylococcus aureus craniotomy infection41
Hydroxychloroquine attenuates neuroinflammation following traumatic brain injury by regulating the TLR4/NF-κB signaling pathway41
Soluble TREM2 is associated with death and cardiovascular events after acute ischemic stroke: an observational study from CATIS41
Lowering blood cholesterol does not affect neuroinflammation in experimental autoimmune encephalomyelitis40
Interferon-induced GTP-binding protein MX1 drives hyperexcitability in peripheral nerves: a novel mechanism in small fiber neuropathy40
Temporally resolved single-cell RNA sequencing reveals protective and pathological responses during herpes simplex virus CNS infection40
25-hydroxycholesterol promotes brain cytokine production and leukocyte infiltration in a mouse model of lipopolysaccharide-induced neuroinflammation40
Ethanol-activated microglial exosomes induce MCP1 signaling mediated death of stress-regulatory proopiomelanocortin neurons in the developing hypothalamus40
Transcriptomic analysis unveils bona fide molecular signatures of microglia under conditions of homeostasis and viral encephalitis39
Reduced microglia activation following metformin administration or microglia ablation is sufficient to prevent functional deficits in a mouse model of neonatal stroke39
Circulatory extracellular vesicles transport complement C1q for promoting neuronal amyloid-β production in Alzheimer’s disease39
Impaired response of blood neutrophils to cell-death stimulus differentiates AQP4-IgG-seropositive NMOSD from MOGAD39
RhANP attenuates endotoxin-derived cognitive dysfunction through subdiaphragmatic vagus nerve-mediated gut microbiota–brain axis38
Bone marrow–derived emergency monopoiesis drives brain–lung axis injury after traumatic brain injury via IL-138
Sitagliptin eye drops prevent the impairment of retinal neurovascular unit in the new Trpv2+/− rat model38
Soluble CSF1R promotes microglial activation and amyloid clearance in alzheimer’s disease38
Erythrocyte–brain endothelial interactions induce microglial responses and cerebral microhemorrhages in vivo37
Transcriptome alterations in peripheral blood B cells of patients with multiple sclerosis receiving immune reconstitution therapy37
Targeting neuroinflammation as a preventive and therapeutic approach for perioperative neurocognitive disorders37
MAVS signaling shapes microglia responses to neurotropic virus infection37
Central activation of the fatty acid sensor GPR120 suppresses microglia reactivity and alleviates sickness- and anxiety-like behaviors37
Impaired membrane lipids in ischemic stroke: a key player in inflammation and thrombosis37
Type I/type III IFN and related factors regulate JEV infection and BBB endothelial integrity37
PARP9 exacerbates apoptosis and neuroinflammation via the PI3K pathway in the thalamus and hippocampus and cognitive decline after cortical infarction36
The contribution of the meningeal immune interface to neuroinflammation in traumatic brain injury36
Inflammation-induced lysosomal dysfunction in human iPSC-derived microglia is exacerbated by APOE 4/4 genotype36
Supraphysiologic doses of 17β-estradiol aggravate depression-like behaviors in ovariectomized mice possibly via regulating microglial responses and brain glycerophospholipid metabolism35
Effects of diabetes on microglial physiology: a systematic review of in vitro, preclinical and clinical studies35
P2X7-CaMKII drives 5-LOX nuclear translocation to impair microglial function after subarachnoid hemorrhage35
Intermittent theta-burst stimulation improves motor function by inhibiting neuronal pyroptosis and regulating microglial polarization via TLR4/NFκB/NLRP3 signaling pathway in cerebral ischemic mice35
Homer1 promotes the conversion of A1 astrocytes to A2 astrocytes and improves the recovery of transgenic mice after intracerebral hemorrhage35
Transcriptional and neuroprotective effects of hexokinase-2 inhibitors administered after stroke35
Administration of Maresin-1 ameliorates the physiopathology of experimental autoimmune encephalomyelitis35
Impairment of neuronal tyrosine phosphatase STEP worsens post-ischemic inflammation and brain injury under hypertensive condition35
Cyanidin-3-O-glucoside protects the brain and improves cognitive function in APPswe/PS1ΔE9 transgenic mice model35
RiboTag-based RNA profiling uncovers oligodendroglial lineage-specific inflammation in autoimmune encephalomyelitis: implications for pathogenesis35
Neuroinflammation, memory, and depression: new approaches to hippocampal neurogenesis35
Microglia and Immune cells interactions in multiple sclerosis cognitive impairment: a postmortem study34
Longitudinal cerebrospinal fluid measurements show glial hypo- and hyperactivation in predementia Alzheimer’s disease34
AAV-mediated delivery of a proliferation inducing ligand (APRIL) to cortical neurons limits inflammation and demyelination in the corpus callosum of the cuprizone mouse model34
Hypothalamic kisspeptin alleviates myasthenia gravis by regulating Th1/Th17/Treg balance through Inhibition of NF-κB signaling pathway34
Immune subversion by Leishmania infantum parasites suppresses NLRP3-driven inflammatory responses in amyloid-β-activated microglia34
Correction to: Cathepsin C promotes microglia M1 polarization and aggravates neuroinflammation via activation of Ca2+-dependent PKC/p38MAPK/NF-κB pathway34
Ambient RNAs removal of cortex-specific snRNA-seq reveals Apoe+ microglia/macrophage after deeper cerebral hypoperfusion in mice34
Neuroimmune proteins can differentiate between tauopathies34
Interleukin-9 protects from microglia- and TNF-mediated synaptotoxicity in experimental multiple sclerosis34
Moss-derived human complement factor H modulates retinal immune response and attenuates retinal degeneration34
Morphine-induced microglial immunosuppression via activation of insufficient mitophagy regulated by NLRX133
Role of SPAK–NKCC1 signaling cascade in the choroid plexus blood–CSF barrier damage after stroke33
Perivascular macrophages in high-fat diet-induced hypothalamic inflammation33
Microglia sustain anterior cingulate cortex neuronal hyperactivity in nicotine-induced pain33
Fascin-1 limits myosin activity in microglia to control mechanical characterization of the injured spinal cord33
Inhibition of discoidin domain receptor (DDR)-1 with nilotinib alters CSF miRNAs and is associated with reduced inflammation and vascular fibrosis in Alzheimer’s disease32
Deletion of CD47 from Schwann cells and macrophages hastens myelin disruption/dismantling and scavenging in Schwann cells and augments myelin debris phagocytosis in macrophages32
Role of myeloid cells in ischemic retinopathies: recent advances and unanswered questions32
Differential contribution of THIK-1 K+ channels and P2X7 receptors to ATP-mediated neuroinflammation by human microglia32
P2X7 receptor antagonists modulate experimental autoimmune neuritis via regulation of NLRP3 inflammasome activation and Th17 and Th1 cell differentiation32
Western diet increases brain metabolism and adaptive immune responses in a mouse model of amyloidosis32
Models of microglia depletion and replenishment elicit protective effects to alleviate vascular and neuronal damage in the diabetic murine retina32
Integrated single-cell transcriptomics of cerebrospinal fluid cells in treatment-naïve multiple sclerosis32
The novel HS-mimetic, Tet-29, regulates immune cell trafficking across barriers of the CNS during inflammation32
Fatty acids role in multiple sclerosis as “metabokines”32
Impact of noradrenergic inhibition on neuroinflammation and pathophysiology in mouse models of Alzheimer’s disease32
Upregulated astrocytic HDAC7 induces depression-like disorders via deacetylating PINK1 and inhibiting mitophagy32
Up-regulated succinylation modifications induce a senescence phenotype in microglia by altering mitochondrial energy metabolism32
Interleukin-6 deficiency reduces neuroinflammation by inhibiting the STAT3-cGAS-STING pathway in Alzheimer’s disease mice31
Tumor necrosis factor regulates leukocyte recruitment but not bacterial persistence during Staphylococcus aureus craniotomy infection31
Anti-inflammatory role of GM1 and other gangliosides on microglia31
Repeated LPS induces training and tolerance of microglial responses across brain regions31
Astroglial modulation of synaptic function in the non-demyelinated cerebellar cortex is dependent on MyD88 signaling in a model of toxic demyelination31
Acute postnatal inflammation alters adult microglial responses to LPS that are sex-, region- and timing of postnatal inflammation-dependent31
N-acetylglucosamine inhibits inflammation and neurodegeneration markers in multiple sclerosis: a mechanistic trial31
LncBADR promotes T cell-mediated autoimmunity by binding Mccc1 and Pcca to regulate BCAAs degradation31
LPA1 signaling drives Schwann cell dedifferentiation in experimental autoimmune neuritis31
Systemic inflammatory markers of persistent cerebral edema after aneurysmal subarachnoid hemorrhage30
Astrocytic CXCL5 hinders microglial phagocytosis of myelin debris and aggravates white matter injury in chronic cerebral ischemia30
Synaptic loss and progression in mice infected with Angiostrongylus cantonensis in the early stage30
Single cell RNA sequencing after moderate traumatic brain injury: effects of therapeutic hypothermia30
Glyceryl triacetate promotes blood–brain barrier recovery after ischemic stroke through lipogenesis-mediated IL-33 in mice30
Connexin 43 gap junction-mediated astrocytic network reconstruction attenuates isoflurane-induced cognitive dysfunction in mice30
Innate immune stimulation by monophosphoryl lipid A prevents chronic social defeat stress-induced anxiety-like behaviors in mice30
The interaction of tPA with NMDAR1 drives neuroinflammation and neurodegeneration in α-synuclein-mediated neurotoxicity30
AMPK-autophagy-mediated inhibition of microRNA-30a-5p alleviates morphine tolerance via SOCS3-dependent neuroinflammation suppression30
SPOCK2 modulates neuropathic pain by interacting with MT1-MMP to regulate astrocytic MMP-2 activation in rats with chronic constriction injury30
Fucoidan reduces NET accumulation and alleviates chemotherapy-induced peripheral neuropathy via the gut–blood–DRG axis29
Cholesterol in the CNS: functions, recycling and remyelination29
Inhibition of NADPH oxidase 2 enhances resistance to viral neuroinflammation by facilitating M1-polarization of macrophages at the extraneural tissues29
Asperosaponin VI ameliorates the CMS-induced depressive-like behaviors by inducing a neuroprotective microglial phenotype in hippocampus via PPAR-γ pathway29
Distinct features of B cell receptors in neuromyelitis optica spectrum disorder among CNS inflammatory demyelinating diseases29
Japanese encephalitis virus-induced DNA methylation contributes to blood-brain barrier permeability by modulating tight junction protein expression29
Using zebrafish to understand reciprocal interactions between the nervous and immune systems and the microbial world29
Growth differentiation factor 15 aggravates sepsis-induced cognitive and memory impairments by promoting microglial inflammatory responses and phagocytosis28
Infiltrating myeloid cell-derived properdin markedly promotes microglia-mediated neuroinflammation after ischemic stroke28
Aberrant copper metabolism and hepatic inflammation cause neurological manifestations in a mouse model of Wilson’s disease28
Hippocampal microRNA-26a-3p deficit contributes to neuroinflammation and behavioral disorders via p38 MAPK signaling pathway in rats28
The protective PLCγ2-P522R variant mitigates Alzheimer’s disease-associated pathologies by enhancing beneficial microglial functions28
Synergistic effects of repeated transcranial magnetic stimulation and mesenchymal stem cells transplantation on alleviating neuroinflammation and PANoptosis in cerebral ischemia28
Interleukin-2 improves insulin sensitivity through hypothalamic sympathetic activation in obese mice28
Mitochondrial protective effects caused by the administration of mefenamic acid in sepsis28
Neuroimmune modulation in liver pathophysiology28
The brain washing system in sepsis-associated encephalopathy28
The role of CD56bright NK cells in neurodegenerative disorders28
Biomass smoke inhalation promotes neuroinflammatory and metabolomic temporal changes in the hippocampus of female mice28
H3K18 lactylation-mediated nucleotide-binding oligomerization domain-2 (NOD2) expression promotes bilirubin-induced pyroptosis of astrocytes28
Extracellular vesicles derived from mesenchymal stem cells alleviate neuroinflammation and mechanical allodynia in interstitial cystitis rats by inhibiting NLRP3 inflammasome activation28
Macrophage expression of P2X7 controls autoimmune uveitis27
Long-term impact of maternal obesity on the gliovascular unit and ephrin signaling in the hippocampus of adult offspring27
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