Journal of Neuroinflammation

Papers
(The TQCC of Journal of Neuroinflammation is 22. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-08-01 to 2025-08-01.)
ArticleCitations
Correction: Smek1 deficiency exacerbates experimental autoimmune encephalomyelitis by activating proinflammatory microglia and suppressing the IDO1-AhR pathway480
Correction to: Vagus nerve stimulation modulates hippocampal inflammation caused by continuous stress in rats366
Intrauterine inflammation and postnatal intravenous dopamine alter the neurovascular unit in preterm newborn lambs332
Extracellular vesicles produced by HIV-1 Nef-expressing cells induce myelin impairment and oligodendrocyte damage in the mouse central nervous system315
Correction to: Pharmacologic activation of cholinergic alpha7 nicotinic receptors mitigates depressive-like behavior in a mouse model of chronic stress288
Zika virus infection of mature neurons from immunocompetent mice generates a disease-associated microglia and a tauopathy-like phenotype in link with a delayed interferon beta response218
Selective neuronal expression of progranulin is sufficient to provide neuroprotective and anti-inflammatory effects after traumatic brain injury212
Citrobacter rodentium infection impairs dopamine metabolism and exacerbates the pathology of Parkinson’s disease in mice200
Gut microbiota and their influence in brain cancer milieu192
Fractalkine isoforms differentially regulate microglia-mediated inflammation and enhance visual function in the diabetic retina172
Integrin Mac1 mediates paraquat and maneb-induced learning and memory impairments in mice through NADPH oxidase–NLRP3 inflammasome axis-dependent microglial activation169
The associations between plasma soluble Trem1 and neurological diseases: a Mendelian randomization study165
Inhibition of neutrophil extracellular traps alleviates blood–brain barrier disruption and cognitive dysfunction via Wnt3/β-catenin/TCF4 signaling in sepsis-associated encephalopathy148
Regulation of the p75 neurotrophin receptor attenuates neuroinflammation and stimulates hippocampal neurogenesis in experimental Streptococcus pneumoniae meningitis142
Phosphatidate phosphatase Lipin1 alters mitochondria-associated endoplasmic reticulum membranes (MAMs) homeostasis: effects which contribute to the development of diabetic encephalopathy135
Carotid artery vascular stenosis causes the blood-CSF barrier damage and neuroinflammation127
Protein kinase B (AKT) upregulation and Thy-1-αvβ3 integrin-induced phosphorylation of Connexin43 by activated AKT in astrogliosis123
IL-7Rα on CD4+ T cells is required for their survival and the pathogenesis of experimental autoimmune encephalomyelitis114
HIF1α-dependent hypoxia response in myeloid cells requires IRE1α105
How the gut microbiota impacts neurodegenerative diseases by modulating CNS immune cells99
Argonaute-2 protects the neurovascular unit from damage caused by systemic inflammation99
Flow cytometry identifies changes in peripheral and intrathecal lymphocyte patterns in CNS autoimmune disorders and primary CNS malignancies99
HMGB1 mediates synaptic loss and cognitive impairment in an animal model of sepsis-associated encephalopathy98
TPM1 mediates inflammation downstream of TREM2 via the PKA/CREB signaling pathway97
Maternal immunoglobulin G affects brain development of mouse offspring97
The deficient CLEC5A ameliorates the behavioral and pathological deficits via the microglial Aβ clearance in Alzheimer’s disease mouse model97
Macrophage elastase (MMP12) critically contributes to the development of subretinal fibrosis96
Microglia-derived exosomes modulate myelin regeneration via miR-615-5p/MYRF axis95
Marine fungal metabolite butyrolactone I prevents cognitive deficits by relieving inflammation and intestinal microbiota imbalance on aluminum trichloride-injured zebrafish91
Exercise suppresses neuroinflammation for alleviating Alzheimer’s disease87
Preoperative gut microbiota of POCD patients induces pre- and postoperative cognitive impairment and systemic inflammation in rats85
LXR agonism for CNS diseases: promises and challenges85
Therapeutic intervention in neuroinflammation for neovascular ocular diseases through targeting the cGAS-STING-necroptosis pathway84
Elucidating the specific mechanisms of the gut-brain axis: the short-chain fatty acids-microglia pathway84
Inhibition of histone deacetylase 6 alleviates neuropathic pain via direct regulating post-translation of spinal STAT3 and decreasing downstream C-C Motif Chemokine Ligand 7 synthesis83
Hypochlorous acid derived from microglial myeloperoxidase could mediate high-mobility group box 1 release from neurons to amplify brain damage in cerebral ischemia–reperfusion injury83
Tregs dysfunction aggravates postoperative cognitive impairment in aged mice83
Profiling the neuroimmune cascade in 3xTg-AD mice exposed to successive mild traumatic brain injuries82
Macrophage exosomal miR-30c-2-3p in atherosclerotic plaques aggravates microglial neuroinflammation during large-artery atherosclerotic stroke via TGF-β/SMAD2 pathway81
Role of lipocalin-2 in surgery-induced cognitive decline in mice: a signal from neuron to microglia81
Chronic rapid eye movement sleep deprivation aggravates the pathogenesis of Alzheimer’s disease by decreasing brain O-GlcNAc cycling in mice80
Inflammasomes at the crossroads of traumatic brain injury and post-traumatic epilepsy79
Immunotherapy with an antibody against CD1d modulates neuroinflammation in an α-synuclein transgenic model of Lewy body like disease79
Diffuse traumatic brain injury induced stimulator of interferons (STING) signaling in microglia drives cortical neuroinflammation, neuronal dysfunction, and impaired cognition79
H3K27me3 of Rnf19a promotes neuroinflammatory response during Japanese encephalitis virus infection79
Correction: Hydrogen sulfide-releasing cyclooxygenase inhibitor ATB-346 enhances motor function and reduces cortical lesion volume following traumatic brain injury in mice77
IDO1 modulates pain sensitivity and comorbid anxiety in chronic migraine through microglial activation and synaptic pruning77
Ubiquitination-mediated upregulation of glycolytic enzyme MCT4 in promoting astrocyte reactivity during neuroinflammation76
Deterioration of neuroimmune homeostasis in Alzheimer’s Disease patients who survive a COVID-19 infection74
Supporting the differential diagnosis of connective tissue diseases with neurological involvement by blood and cerebrospinal fluid flow cytometry74
Innate immune sensors and regulators at the blood brain barrier: focus on toll-like receptors and inflammasomes as mediators of neuro-immune crosstalk and inflammation73
Exogenous monocyte myeloid-derived suppressor cells ameliorate immune imbalance, neuroinflammation and cognitive impairment in 5xFAD mice infected with Porphyromonas gingivalis72
A systematic review of the causes and consequences of spreading depolarization in neuroinflammation; implications for neurovascular disorders72
NLRX1 limits inflammatory neurodegeneration in the anterior visual pathway71
Nanoparticulate MgH2 ameliorates anxiety/depression-like behaviors in a mouse model of multiple sclerosis by regulating microglial polarization and oxidative stress70
MicroRNA-155-5p promotes neuroinflammation and central sensitization via inhibiting SIRT1 in a nitroglycerin-induced chronic migraine mouse model70
Single-cell RNA sequencing reveals peripheral blood leukocyte responses to spinal cord injury in mice with humanised immune systems69
TLR4-dependent neuroinflammation mediates LPS-driven food-reward alterations during high-fat exposure69
Injection of amyloid-β to lateral ventricle induces gut microbiota dysbiosis in association with inhibition of cholinergic anti-inflammatory pathways in Alzheimer’s disease68
Remibrutinib (LOU064) inhibits neuroinflammation driven by B cells and myeloid cells in preclinical models of multiple sclerosis68
Nisin a probiotic bacteriocin mitigates brain microbiome dysbiosis and Alzheimer’s disease-like neuroinflammation triggered by periodontal disease68
Distinguishing the effects of systemic CSF1R inhibition by PLX3397 on microglia and peripheral immune cells67
Long-term running exercise improves cognitive function and promotes microglial glucose metabolism and morphological plasticity in the hippocampus of APP/PS1 mice66
Decoding Behcet’s Uveitis: an In-depth review of pathogenesis and therapeutic advances66
Compromised endothelial Wnt/β-catenin signaling mediates the blood-brain barrier disruption and leads to neuroinflammation in endotoxemia64
Immune response and pathogen invasion at the choroid plexus in the onset of cerebral toxoplasmosis64
Sequential treatment with a TNFR2 agonist and a TNFR1 antagonist improves outcomes in a humanized mouse model for MS64
AIBP controls TLR4 inflammarafts and mitochondrial dysfunction in a mouse model of Alzheimer’s disease63
The interaction between central and peripheral immune systems in methamphetamine use disorder: current status and future directions63
α7 Nicotinic acetylcholine receptor: a key receptor in the cholinergic anti-inflammatory pathway exerting an antidepressant effect63
Nanozymes in neuropathic pain: strategies bridging oxidative stress, mitochondrial repair, and neuroimmune modulation for targeted therapy62
Interleukin-3 is associated with sTREM2 and mediates the correlation between amyloid-β and tau pathology in Alzheimer’s disease62
Febrile temperature-regulated TRPV1 in CD4+ T cells mediates neuroinflammation in complex febrile seizures61
GAS6 as a potential target to alleviate neuroinflammation during Japanese encephalitis in mouse models60
Cladribine treatment improves cortical network functionality in a mouse model of autoimmune encephalomyelitis60
Pericytes are protective in experimental pneumococcal meningitis through regulating leukocyte infiltration and blood–brain barrier function60
Brain transcriptome analysis of a CLN2 mouse model as a function of disease progression59
Repurposing of epalrestat for neuroprotection in parkinson’s disease via activation of the KEAP1/Nrf2 pathway59
Appearance of claudin-5+ leukocyte subtypes in the blood and CNS during progression of EAE59
Absence of the lectin-like domain of thrombomodulin reduces HSV-1 lethality of mice with increased microglia responses58
Exploratory analysis of a Novel RACK1 mutation and its potential role in epileptic seizures via Microglia activation58
Brd4 expression in CD4 T cells and in microglia promotes neuroinflammation in experimental autoimmune encephalomyelitis57
APOEε4 alters ApoE and Fabp7 in frontal cortex white matter in prodromal Alzheimer's disease57
Inhibition of UTX/KDM6A improves recovery of spinal cord injury by attenuating BSCB permeability and macrophage infiltration through the MLCK/p-MLC pathway57
Satellite microglia: marker of traumatic brain injury and regulator of neuronal excitability57
Integration of National Health Insurance claims data and animal models reveals fexofenadine as a promising repurposed drug for Parkinson’s disease55
Prolactin deficiency drives diabetes-associated cognitive dysfunction by inducing microglia-mediated synaptic loss55
CSF sTREM2 in neurological diseases: a two-sample Mendelian randomization study55
Spatiotemporal dynamic changes of meningeal microenvironment influence meningeal lymphatic function following subarachnoid hemorrhage: from inflammatory response to tissue remodeling55
Morinda officinalis oligosaccharides mitigate depression-like behaviors in hypertension rats by regulating Mfn2-mediated mitophagy54
The multifaceted role of vitreous hyalocytes: Orchestrating inflammation, angiomodulation and erythrophagocytosis in proliferative diabetic retinopathy54
High-fat diet-induced diabetes leads to vascular alterations, pericyte reduction, and perivascular depletion of microglia in a 6-OHDA toxin model of Parkinson disease53
Dimethyl fumarate improves cognitive impairment and neuroinflammation in mice with Alzheimer’s disease53
TRPV4 contributes to ER stress and inflammation: implications for Parkinson’s disease53
The BET PROTAC inhibitor dBET6 protects against retinal degeneration and inhibits the cGAS-STING in response to light damage53
Hepcidin deficiency impairs hippocampal neurogenesis and mediates brain atrophy and memory decline in mice53
Mitochondrial DNA leakage: underlying mechanisms and therapeutic implications in neurological disorders52
TYROBP/DAP12 knockout in Huntington’s disease Q175 mice cell-autonomously decreases microglial expression of disease-associated genes and non-cell-autonomously mitigates astrogliosis and motor deterio52
Biologic TNF-α inhibitors reduce microgliosis, neuronal loss, and tau phosphorylation in a transgenic mouse model of tauopathy51
Rifaximin-mediated gut microbiota regulation modulates the function of microglia and protects against CUMS-induced depression-like behaviors in adolescent rat51
Extracellular vesicles from mesenchymal stem cells reduce neuroinflammation in hippocampus and restore cognitive function in hyperammonemic rats51
Traumatic brain injury alters the effects of class II invariant peptide (CLIP) antagonism on chronic meningeal CLIP + B cells, neuropathology, and neurobehavioral impairment in 5xFAD mice51
Complement inhibition targets a rich-club within the neuroinflammatory network after stroke to improve radiographic and functional outcomes51
Inflammatory monocytes and microglia play independent roles in inflammatory ictogenesis50
CXCR5 down-regulation alleviates cognitive dysfunction in a mouse model of sepsis-associated encephalopathy: potential role of microglial autophagy and the p38MAPK/NF-κB/STAT3 signaling pathway50
Tryptophan-rich diet and its effects on Htr7+ Tregs in alleviating neuroinflammation and cognitive impairment induced by lipopolysaccharide50
Prostaglandin EP2 receptor antagonist ameliorates neuroinflammation in a two-hit mouse model of Alzheimer’s disease49
Single-cell RNA sequencing reveals a landscape and targeted treatment of ferroptosis in retinal ischemia/reperfusion injury49
Retraction Note to: Regulation of autophagy by the nuclear factor κB signaling pathway in the hippocampus of rats with sepsis49
Proteomic profiling identifies novel inflammation-related plasma proteins associated with ischemic stroke outcome49
Human PMSCs-derived small extracellular vesicles alleviate neuropathic pain through miR-26a-5p/Wnt5a in SNI mice model49
Therapeutic reduction of neurocan in murine intracerebral hemorrhage lesions promotes oligodendrogenesis and functional recovery49
Neuroinflammatory transcriptional programs induced in rhesus pre-frontal cortex white matter during acute SHIV infection48
Elevated lipoprotein(a) and lipoprotein-associated phospholipase A2 are associated with unfavorable functional outcomes in patients with ischemic stroke48
Astrocytic stress response is induced by exposure to astrocyte-binding antibodies expressed by plasmablasts from pediatric patients with acute transverse myelitis48
The glucocorticoid receptor as a master regulator of the Müller cell response to diabetic conditions in mice48
Asrij/OCIAD1 depletion reduces inflammatory microglial activation and ameliorates Aβ pathology in an Alzheimer’s disease mouse model48
Noninvasive ultrasound stimulation to treat myocarditis through splenic neuro-immune regulation48
Upregulation of TRPC5 in hippocampal excitatory synapses improves memory impairment associated with neuroinflammation in microglia knockout IL-10 mice47
The insular cortex is not insular in thyroid eye disease: neuroimaging revelations of central–peripheral system interaction47
Soluble CD27 is an intrathecal biomarker of T-cell-mediated lesion activity in multiple sclerosis46
Sex differences and similarities in the neuroimmune response to central administration of poly I:C46
Mild-to-severe traumatic brain injury in children: altered cytokines reflect severity46
Microglial–oligodendrocyte interactions in myelination and neurological function recovery after traumatic brain injury46
Ogt-mediated O-GlcNAcylation inhibits astrocytes activation through modulating NF-κB signaling pathway46
25-Hydroxycholesterol modulates microglial function and exacerbates Alzheimer’s disease pathology: mechanistic insights and therapeutic potential of cholesterol esterification inhibition45
Impact of disease-modifying therapy on dendritic cells and exploring their immunotherapeutic potential in multiple sclerosis45
An AGS-associated mutation in ADAR1 catalytic domain results in early-onset and MDA5-dependent encephalopathy with IFN pathway activation in the brain45
Hydroxychloroquine attenuates neuroinflammation following traumatic brain injury by regulating the TLR4/NF-κB signaling pathway44
Extended interval dosing of ocrelizumab modifies the repopulation of B cells without altering the clinical efficacy in multiple sclerosis44
[18F]F-DED PET imaging of reactive astrogliosis in neurodegenerative diseases: preclinical proof of concept and first-in-human data44
Transfer of patient’s peripheral blood mononuclear cells (PBMCs) disrupts blood–brain barrier and induces anti-NMDAR encephalitis: a study of novel humanized PBMC mouse model44
Inflammasome inhibition protects dopaminergic neurons from α-synuclein pathology in a model of progressive Parkinson’s disease44
Fenebrutinib, a Bruton’s tyrosine kinase inhibitor, blocks distinct human microglial signaling pathways44
Cinnamaldehyde and its combination with deferoxamine ameliorate inflammation, ferroptosis and hematoma expansion after intracerebral hemorrhage in mice44
Neuroprotective effects of GSK-343 in an in vivo model of MPTP-induced nigrostriatal degeneration43
Transient post-operative overexpression of CXCR2 on monocytes of traumatic brain injury patients drives monocyte chemotaxis toward cerebrospinal fluid and enhances monocyte-mediated immunogenic cell d43
SRGN amplifies microglia-mediated neuroinflammation and exacerbates ischemic brain injury43
Type I/type III IFN and related factors regulate JEV infection and BBB endothelial integrity42
Interleukin-6 actions in the hypothalamus protects against obesity and is involved in the regulation of neurogenesis42
Reduced microglia activation following metformin administration or microglia ablation is sufficient to prevent functional deficits in a mouse model of neonatal stroke42
Fidgetin-like 2 knockdown increases acute neuroinflammation and improves recovery in a rat model of spinal cord injury42
TAK1 mediates neuronal pyroptosis in early brain injury after subarachnoid hemorrhage42
Supraphysiologic doses of 17β-estradiol aggravate depression-like behaviors in ovariectomized mice possibly via regulating microglial responses and brain glycerophospholipid metabolism42
Temporal changes in regulatory T cell subsets defined by the transcription factor Helios in stroke and their potential role in stroke-associated infection: a prospective case–control study41
Neuroimmune multi-hit perspective of coronaviral infection40
Soluble TREM2 is associated with death and cardiovascular events after acute ischemic stroke: an observational study from CATIS40
The contribution of the meningeal immune interface to neuroinflammation in traumatic brain injury40
Impaired response of blood neutrophils to cell-death stimulus differentiates AQP4-IgG-seropositive NMOSD from MOGAD40
PARP9 exacerbates apoptosis and neuroinflammation via the PI3K pathway in the thalamus and hippocampus and cognitive decline after cortical infarction40
Lowering blood cholesterol does not affect neuroinflammation in experimental autoimmune encephalomyelitis40
Impairment of neuronal tyrosine phosphatase STEP worsens post-ischemic inflammation and brain injury under hypertensive condition40
Central activation of the fatty acid sensor GPR120 suppresses microglia reactivity and alleviates sickness- and anxiety-like behaviors39
Transcriptomic analysis unveils bona fide molecular signatures of microglia under conditions of homeostasis and viral encephalitis39
IL-10 production by granulocytes promotes Staphylococcus aureus craniotomy infection39
Temporally resolved single-cell RNA sequencing reveals protective and pathological responses during herpes simplex virus CNS infection39
Impaired membrane lipids in ischemic stroke: a key player in inflammation and thrombosis39
Targeting neuroinflammation as a preventive and therapeutic approach for perioperative neurocognitive disorders39
Inflammation-induced lysosomal dysfunction in human iPSC-derived microglia is exacerbated by APOE 4/4 genotype39
25-hydroxycholesterol promotes brain cytokine production and leukocyte infiltration in a mouse model of lipopolysaccharide-induced neuroinflammation38
Sitagliptin eye drops prevent the impairment of retinal neurovascular unit in the new Trpv2+/− rat model38
RhANP attenuates endotoxin-derived cognitive dysfunction through subdiaphragmatic vagus nerve-mediated gut microbiota–brain axis38
Administration of Maresin-1 ameliorates the physiopathology of experimental autoimmune encephalomyelitis38
Erythrocyte–brain endothelial interactions induce microglial responses and cerebral microhemorrhages in vivo38
MAVS signaling shapes microglia responses to neurotropic virus infection38
Transcriptome alterations in peripheral blood B cells of patients with multiple sclerosis receiving immune reconstitution therapy38
Homer1 promotes the conversion of A1 astrocytes to A2 astrocytes and improves the recovery of transgenic mice after intracerebral hemorrhage37
Effects of diabetes on microglial physiology: a systematic review of in vitro, preclinical and clinical studies37
Ethanol-activated microglial exosomes induce MCP1 signaling mediated death of stress-regulatory proopiomelanocortin neurons in the developing hypothalamus37
Intermittent theta-burst stimulation improves motor function by inhibiting neuronal pyroptosis and regulating microglial polarization via TLR4/NFκB/NLRP3 signaling pathway in cerebral ischemic mice37
Neuroinflammation, memory, and depression: new approaches to hippocampal neurogenesis37
Correction to: Cathepsin C promotes microglia M1 polarization and aggravates neuroinflammation via activation of Ca2+-dependent PKC/p38MAPK/NF-κB pathway37
Cyanidin-3-O-glucoside protects the brain and improves cognitive function in APPswe/PS1ΔE9 transgenic mice model37
TRPV4-induced Müller cell gliosis and TNF-α elevation-mediated retinal ganglion cell apoptosis in glaucomatous rats via JAK2/STAT3/NF-κB pathway37
Ambient RNAs removal of cortex-specific snRNA-seq reveals Apoe+ microglia/macrophage after deeper cerebral hypoperfusion in mice36
Impact of noradrenergic inhibition on neuroinflammation and pathophysiology in mouse models of Alzheimer’s disease36
Up-regulated succinylation modifications induce a senescence phenotype in microglia by altering mitochondrial energy metabolism36
Neuroimmune proteins can differentiate between tauopathies36
Hypothalamic kisspeptin alleviates myasthenia gravis by regulating Th1/Th17/Treg balance through Inhibition of NF-κB signaling pathway36
Perivascular macrophages in high-fat diet-induced hypothalamic inflammation35
Microglia and Immune cells interactions in multiple sclerosis cognitive impairment: a postmortem study35
RiboTag-based RNA profiling uncovers oligodendroglial lineage-specific inflammation in autoimmune encephalomyelitis: implications for pathogenesis35
Global gene expression and chromatin accessibility of the peripheral nervous system in animal models of persistent pain35
N-acetylglucosamine inhibits inflammation and neurodegeneration markers in multiple sclerosis: a mechanistic trial34
Moss-derived human complement factor H modulates retinal immune response and attenuates retinal degeneration34
Role of SPAK–NKCC1 signaling cascade in the choroid plexus blood–CSF barrier damage after stroke34
Deletion of CD47 from Schwann cells and macrophages hastens myelin disruption/dismantling and scavenging in Schwann cells and augments myelin debris phagocytosis in macrophages34
Systemic inflammation alters the neuroinflammatory response: a prospective clinical trial in traumatic brain injury34
Role of myeloid cells in ischemic retinopathies: recent advances and unanswered questions34
Models of microglia depletion and replenishment elicit protective effects to alleviate vascular and neuronal damage in the diabetic murine retina33
Microglia sustain anterior cingulate cortex neuronal hyperactivity in nicotine-induced pain33
Fascin-1 limits myosin activity in microglia to control mechanical characterization of the injured spinal cord33
Inhibition of discoidin domain receptor (DDR)-1 with nilotinib alters CSF miRNAs and is associated with reduced inflammation and vascular fibrosis in Alzheimer’s disease32
Differential contribution of THIK-1 K+ channels and P2X7 receptors to ATP-mediated neuroinflammation by human microglia32
Fatty acids role in multiple sclerosis as “metabokines”32
Neurofilament light: a possible prognostic biomarker for treatment of vascular contributions to cognitive impairment and dementia32
Interleukin-6 deficiency reduces neuroinflammation by inhibiting the STAT3-cGAS-STING pathway in Alzheimer’s disease mice32
The novel HS-mimetic, Tet-29, regulates immune cell trafficking across barriers of the CNS during inflammation32
Repeated LPS induces training and tolerance of microglial responses across brain regions31
HMGB1 mediates cognitive impairment caused by the NLRP3 inflammasome in the late stage of traumatic brain injury31
Integrated single-cell transcriptomics of cerebrospinal fluid cells in treatment-naïve multiple sclerosis31
P2X7 receptor antagonists modulate experimental autoimmune neuritis via regulation of NLRP3 inflammasome activation and Th17 and Th1 cell differentiation31
Interleukin-9 protects from microglia- and TNF-mediated synaptotoxicity in experimental multiple sclerosis31
Longitudinal cerebrospinal fluid measurements show glial hypo- and hyperactivation in predementia Alzheimer’s disease31
Western diet increases brain metabolism and adaptive immune responses in a mouse model of amyloidosis31
NAD+ improves cognitive function and reduces neuroinflammation by ameliorating mitochondrial damage and decreasing ROS production in chronic cerebral hypoperfusion models through Sirt1/PGC-1α pathway31
Morphine-induced microglial immunosuppression via activation of insufficient mitophagy regulated by NLRX131
Japanese encephalitis virus-induced DNA methylation contributes to blood-brain barrier permeability by modulating tight junction protein expression30
The protective PLCγ2-P522R variant mitigates Alzheimer’s disease-associated pathologies by enhancing beneficial microglial functions30
Asperosaponin VI ameliorates the CMS-induced depressive-like behaviors by inducing a neuroprotective microglial phenotype in hippocampus via PPAR-γ pathway30
Mitochondrial protective effects caused by the administration of mefenamic acid in sepsis30
Distinct features of B cell receptors in neuromyelitis optica spectrum disorder among CNS inflammatory demyelinating diseases30
LPA1 signaling drives Schwann cell dedifferentiation in experimental autoimmune neuritis30
AMPK-autophagy-mediated inhibition of microRNA-30a-5p alleviates morphine tolerance via SOCS3-dependent neuroinflammation suppression30
Synaptic loss and progression in mice infected with Angiostrongylus cantonensis in the early stage30
Cholesterol in the CNS: functions, recycling and remyelination30
Astroglial modulation of synaptic function in the non-demyelinated cerebellar cortex is dependent on MyD88 signaling in a model of toxic demyelination30
SPOCK2 modulates neuropathic pain by interacting with MT1-MMP to regulate astrocytic MMP-2 activation in rats with chronic constriction injury30
Single cell RNA sequencing after moderate traumatic brain injury: effects of therapeutic hypothermia30
Extracellular vesicles derived from mesenchymal stem cells alleviate neuroinflammation and mechanical allodynia in interstitial cystitis rats by inhibiting NLRP3 inflammasome activation30
Fucoidan reduces NET accumulation and alleviates chemotherapy-induced peripheral neuropathy via the gut–blood–DRG axis30
Growth differentiation factor 15 aggravates sepsis-induced cognitive and memory impairments by promoting microglial inflammatory responses and phagocytosis30
Biomass smoke inhalation promotes neuroinflammatory and metabolomic temporal changes in the hippocampus of female mice29
Hippocampal microRNA-26a-3p deficit contributes to neuroinflammation and behavioral disorders via p38 MAPK signaling pathway in rats29
Acute postnatal inflammation alters adult microglial responses to LPS that are sex-, region- and timing of postnatal inflammation-dependent29
The role of CD56bright NK cells in neurodegenerative disorders29
Innate immune stimulation by monophosphoryl lipid A prevents chronic social defeat stress-induced anxiety-like behaviors in mice29
Systemic inflammatory markers of persistent cerebral edema after aneurysmal subarachnoid hemorrhage29
Connexin 43 gap junction-mediated astrocytic network reconstruction attenuates isoflurane-induced cognitive dysfunction in mice29
Using zebrafish to understand reciprocal interactions between the nervous and immune systems and the microbial world29
The interaction of tPA with NMDAR1 drives neuroinflammation and neurodegeneration in α-synuclein-mediated neurotoxicity29
Autophagy protein NRBF2 attenuates endoplasmic reticulum stress-associated neuroinflammation and oxidative stress via promoting autophagosome maturation by interacting with Rab7 after SAH29
Tumor necrosis factor regulates leukocyte recruitment but not bacterial persistence during Staphylococcus aureus craniotomy infection29
Neuroimmune modulation in liver pathophysiology28
H3K18 lactylation-mediated nucleotide-binding oligomerization domain-2 (NOD2) expression promotes bilirubin-induced pyroptosis of astrocytes28
Mas receptor activation facilitates innate hematoma resolution and neurological recovery after hemorrhagic stroke in mice28
Infiltrating myeloid cell-derived properdin markedly promotes microglia-mediated neuroinflammation after ischemic stroke28
Synergistic effects of repeated transcranial magnetic stimulation and mesenchymal stem cells transplantation on alleviating neuroinflammation and PANoptosis in cerebral ischemia28
Aberrant copper metabolism and hepatic inflammation cause neurological manifestations in a mouse model of Wilson’s disease28
Astrocytic CXCL5 hinders microglial phagocytosis of myelin debris and aggravates white matter injury in chronic cerebral ischemia28
1α,25-dihydroxyvitamin D3 protects retinal ganglion cells in glaucomatous mice28
Anti-inflammatory role of GM1 and other gangliosides on microglia28
Molecular mimicry of NMDA receptors may contribute to neuropsychiatric symptoms in severe COVID-19 cases28
Gastrointestinal microbiome of ARDS patients induces neuroinflammation and cognitive impairment in mice27
Activation of locus coeruleus-spinal cord noradrenergic neurons alleviates neuropathic pain in mice via reducing neuroinflammation from astrocytes and microglia in spinal dorsal horn27
Semaglultide targets Spp1+ microglia/macrophage to attenuate neuroinflammation following perioperative stroke27
Early administration of umbilical cord blood cells following brief high tidal volume ventilation in preterm sheep: a cautionary tale27
CD22 blockade exacerbates neuroinflammation in Neuromyelitis optica spectrum disorder27
A molecular brain atlas reveals cellular shifts during the repair phase of stroke27
Inhibition of tumour necrosis factor alpha by Etanercept attenuates Shiga toxin-induced brain pathology27
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