Journal of Neuroinflammation

Article	Citations
The semantics of microglia activation: neuroinflammation, homeostasis, and stress	314
Inflammation after spinal cord injury: a review of the critical timeline of signaling cues and cellular infiltration	261
Edaravone ameliorates depressive and anxiety-like behaviors via Sirt1/Nrf2/HO-1/Gpx4 pathway	210
Microglia in depression: an overview of microglia in the pathogenesis and treatment of depression	207
The association of neutrophil to lymphocyte ratio, platelet to lymphocyte ratio, and lymphocyte to monocyte ratio with post-thrombolysis early neurological outcomes in patients with acute ischemic str	185
Mer regulates microglial/macrophage M1/M2 polarization and alleviates neuroinflammation following traumatic brain injury	167
The good, the bad, and the opportunities of the complement system in neurodegenerative disease	160
Cellular infiltration in traumatic brain injury	160
Isoliquiritin ameliorates depression by suppressing NLRP3-mediated pyroptosis via miRNA-27a/SYK/NF-κB axis	160
Astrocytic and microglial cells as the modulators of neuroinflammation in Alzheimer’s disease	158
Neuromyelitis optica spectrum disorders: from pathophysiology to therapeutic strategies	134
NAD+ improves cognitive function and reduces neuroinflammation by ameliorating mitochondrial damage and decreasing ROS production in chronic cerebral hypoperfusion models through Sirt1/PGC-1α pathway	132
Rifaximin-mediated gut microbiota regulation modulates the function of microglia and protects against CUMS-induced depression-like behaviors in adolescent rat	121
Uncovering sex differences of rodent microglia	118
Rutin prevents tau pathology and neuroinflammation in a mouse model of Alzheimer’s disease	117
On inflammatory hypothesis of depression: what is the role of IL-6 in the middle of the chaos?	115
Intermittent theta-burst stimulation improves motor function by inhibiting neuronal pyroptosis and regulating microglial polarization via TLR4/NFκB/NLRP3 signaling pathway in cerebral ischemic mice	114
Low-density lipoprotein receptor (LDLR) regulates NLRP3-mediated neuronal pyroptosis following cerebral ischemia/reperfusion injury	111
The role of Toll-like receptors and neuroinflammation in Parkinson’s disease	109
Annexin A1 protects against cerebral ischemia–reperfusion injury by modulating microglia/macrophage polarization via FPR2/ALX-dependent AMPK-mTOR pathway	108
Tryptophan-kynurenine metabolism: a link between the gut and brain for depression in inflammatory bowel disease	105
Early glycolytic reprogramming controls microglial inflammatory activation	104
Microglia and macrophage exhibit attenuated inflammatory response and ferroptosis resistance after RSL3 stimulation via increasing Nrf2 expression	103
Sirtuin 3 protects against anesthesia/surgery-induced cognitive decline in aged mice by suppressing hippocampal neuroinflammation	102
Cerebrospinal fluid findings in COVID-19: a multicenter study of 150 lumbar punctures in 127 patients	101

Exosomes derived from bone-marrow mesenchymal stem cells alleviate cognitive decline in AD-like mice by improving BDNF-related neuropathology	100
Stroke-induced immunosuppression: implications for the prevention and prediction of post-stroke infections	99
Crosstalk between astrocytes and microglia results in increased degradation of α-synuclein and amyloid-β aggregates	97
Microglial activation contributes to cognitive impairments in rotenone-induced mouse Parkinson’s disease model	97
Activating cGAS–STING axis contributes to neuroinflammation in CVST mouse model and induces inflammasome activation and microglia pyroptosis	92
Emerging role of STING signalling in CNS injury: inflammation, autophagy, necroptosis, ferroptosis and pyroptosis	80
Cellular senescence in the aging retina and developments of senotherapies for age-related macular degeneration	79
Irisin ameliorates neuroinflammation and neuronal apoptosis through integrin αVβ5/AMPK signaling pathway after intracerebral hemorrhage in mice	74
Central nervous system macrophages in progressive multiple sclerosis: relationship to neurodegeneration and therapeutics	71
TAK1 mediates neuronal pyroptosis in early brain injury after subarachnoid hemorrhage	70
Chronic colitis exacerbates NLRP3-dependent neuroinflammation and cognitive impairment in middle-aged brain	69
Mitophagy in neurological disorders	68
Tau and neuroinflammation in Alzheimer’s disease: interplay mechanisms and clinical translation	68
Fluoxetine regulates eEF2 activity (phosphorylation) via HDAC1 inhibitory mechanism in an LPS-induced mouse model of depression	67
The NLRP3 inflammasome: an emerging therapeutic target for chronic pain	66
Relevant mediators involved in and therapies targeting the inflammatory response induced by activation of the NLRP3 inflammasome in ischemic stroke	66
Macrophage to myofibroblast transition contributes to subretinal fibrosis secondary to neovascular age-related macular degeneration	65
CD4+ effector T cells accelerate Alzheimer’s disease in mice	64
Microglial deletion and inhibition alleviate behavior of post-traumatic stress disorder in mice	64
Dysregulated phosphoinositide 3-kinase signaling in microglia: shaping chronic neuroinflammation	63
Microglial amyloid beta clearance is driven by PIEZO1 channels	62
Mechanisms underlying antidepressant effect of transcutaneous auricular vagus nerve stimulation on CUMS model rats based on hippocampal α7nAchR/NF-κB signal pathway	61
Microglia as target for anti-inflammatory approaches to prevent secondary brain injury after subarachnoid hemorrhage (SAH)	61
The role of the adaptive immune system and T cell dysfunction in neurodegenerative diseases	60
Engagement of TREM2 by a novel monoclonal antibody induces activation of microglia and improves cognitive function in Alzheimer’s disease models	59
MicroRNA-155-5p promotes neuroinflammation and central sensitization via inhibiting SIRT1 in a nitroglycerin-induced chronic migraine mouse model	59
Ceria nanoparticles ameliorate white matter injury after intracerebral hemorrhage: microglia-astrocyte involvement in remyelination	58
High-fat diet exacerbates cognitive decline in mouse models of Alzheimer's disease and mixed dementia in a sex-dependent manner	58
Neuroinflammation as an etiological trigger for depression comorbid with inflammatory bowel disease	57
Sestrin2 regulates microglia polarization through mTOR-mediated autophagic flux to attenuate inflammation during experimental brain ischemia	57
SARS-CoV-2 productively infects human brain microvascular endothelial cells	57
miR-19a/b-3p promotes inflammation during cerebral ischemia/reperfusion injury via SIRT1/FoxO3/SPHK1 pathway	57
Mitochondrial dysfunction in microglia: a novel perspective for pathogenesis of Alzheimer’s disease	56
The function of gut microbiota in immune-related neurological disorders: a review	55
Sepsis-associated brain injury: underlying mechanisms and potential therapeutic strategies for acute and long-term cognitive impairments	55
Cordycepin confers long-term neuroprotection via inhibiting neutrophil infiltration and neuroinflammation after traumatic brain injury	55
COVID-19 and cognitive impairment: neuroinvasive and blood‒brain barrier dysfunction	54
Single-cell transcriptomic analysis of the immune cell landscape in the aged mouse brain after ischemic stroke	54
Specific depletion of resident microglia in the early stage of stroke reduces cerebral ischemic damage	54
ALS monocyte-derived microglia-like cells reveal cytoplasmic TDP-43 accumulation, DNA damage, and cell-specific impairment of phagocytosis associated with disease progression	53
Astrocytic A1/A2 paradigm participates in glycogen mobilization mediated neuroprotection on reperfusion injury after ischemic stroke	53
Acute inflammatory profiles differ with sex and age after spinal cord injury	52
DKK3 ameliorates neuropathic pain via inhibiting ASK-1/JNK/p-38-mediated microglia polarization and neuroinflammation	52
Microbial BMAA elicits mitochondrial dysfunction, innate immunity activation, and Alzheimer’s disease features in cortical neurons	52
Intermittent fasting reduces neuroinflammation in intracerebral hemorrhage through the Sirt3/Nrf2/HO-1 pathway	52
Hyperphosphorylated tau mediates neuronal death by inducing necroptosis and inflammation in Alzheimer’s disease	52
Traumatic brain injury results in unique microglial and astrocyte transcriptomes enriched for type I interferon response	52
Potential caveats of putative microglia-specific markers for assessment of age-related cerebrovascular neuroinflammation	51
Oral P. gingivalis impairs gut permeability and mediates immune responses associated with neurodegeneration in LRRK2 R1441G mice	51
Independent risk factors for myasthenic crisis and disease exacerbation in a retrospective cohort of myasthenia gravis patients	51

Spotlight on pyroptosis: role in pathogenesis and therapeutic potential of ocular diseases	51
Neuroinflammation represents a common theme amongst genetic and environmental risk factors for Alzheimer and Parkinson diseases	51
Serum GFAP and NfL as disease severity and prognostic biomarkers in patients with aquaporin-4 antibody-positive neuromyelitis optica spectrum disorder	51
Inflammatory resolution and vascular barrier restoration after retinal ischemia reperfusion injury	50
Sodium para-aminosalicylic acid inhibits manganese-induced NLRP3 inflammasome-dependent pyroptosis by inhibiting NF-κB pathway activation and oxidative stress	50
NLRP3 inhibition attenuates early brain injury and delayed cerebral vasospasm after subarachnoid hemorrhage	50
Long-term running exercise improves cognitive function and promotes microglial glucose metabolism and morphological plasticity in the hippocampus of APP/PS1 mice	50
Gut microbiota is causally associated with poststroke cognitive impairment through lipopolysaccharide and butyrate	50
Neurotransmitter and neuropeptide regulation of mast cell function: a systematic review	49
Metabolic reprogramming mediates hippocampal microglial M1 polarization in response to surgical trauma causing perioperative neurocognitive disorders	48
DSS-induced inflammation in the colon drives a proinflammatory signature in the brain that is ameliorated by prophylactic treatment with the S100A9 inhibitor paquinimod	48
Photobiomodulation inhibits the activation of neurotoxic microglia and astrocytes by inhibiting Lcn2/JAK2-STAT3 crosstalk after spinal cord injury in male rats	48
TRPV4-induced Müller cell gliosis and TNF-α elevation-mediated retinal ganglion cell apoptosis in glaucomatous rats via JAK2/STAT3/NF-κB pathway	48
Small extracellular vesicles encapsulating CCL2 from activated astrocytes induce microglial activation and neuronal apoptosis after traumatic spinal cord injury	47
CCL3 contributes to secondary damage after spinal cord injury	47
Mechanistic insights into the role of the chemokine CCL2/CCR2 axis in dorsal root ganglia to peripheral inflammation and pain hypersensitivity	47
Association of inflammatory markers with cerebral small vessel disease in community-based population	47
Interleukin-1β mediates alterations in mitochondrial fusion/fission proteins and memory impairment induced by amyloid-β oligomers	46
P2X7R-mediated autophagic impairment contributes to central sensitization in a chronic migraine model with recurrent nitroglycerin stimulation in mice	46
Microglia and astrocyte involvement in neurodegeneration and brain cancer	46
Inhibition of CCR2 attenuates neuroinflammation and neuronal apoptosis after subarachnoid hemorrhage through the PI3K/Akt pathway	45
The circadian clock protein Rev-erbα provides neuroprotection and attenuates neuroinflammation against Parkinson’s disease via the microglial NLRP3 inflammasome	45
Expression of SARS-CoV-2-related receptors in cells of the neurovascular unit: implications for HIV-1 infection	44
Epigenetic regulation of innate immune memory in microglia	44
Divanillyl sulfone suppresses NLRP3 inflammasome activation via inducing mitophagy to ameliorate chronic neuropathic pain in mice	44
CXCR5 down-regulation alleviates cognitive dysfunction in a mouse model of sepsis-associated encephalopathy: potential role of microglial autophagy and the p38MAPK/NF-κB/STAT3 signaling pathway	44
GSK872 and necrostatin-1 protect retinal ganglion cells against necroptosis through inhibition of RIP1/RIP3/MLKL pathway in glutamate-induced retinal excitotoxic model of glaucoma	44
The macrophage: a key player in the pathophysiology of peripheral neuropathies	44
Molecular mimicry of NMDA receptors may contribute to neuropsychiatric symptoms in severe COVID-19 cases	44
Tauroursodeoxycholic acid alleviates secondary injury in spinal cord injury mice by reducing oxidative stress, apoptosis, and inflammatory response	43
Pinocembrin ameliorates intermittent hypoxia-induced neuroinflammation through BNIP3-dependent mitophagy in a murine model of sleep apnea	43
p38-TFEB pathways promote microglia activation through inhibiting CMA-mediated NLRP3 degradation in Parkinson's disease	43
Microglia dynamics in aging-related neurobehavioral and neuroinflammatory diseases	43
Interplay between Müller cells and microglia aggravates retinal inflammatory response in experimental glaucoma	43
TREM2 activation alleviates neural damage via Akt/CREB/BDNF signalling after traumatic brain injury in mice	42
Attenuating vascular stenosis-induced astrogliosis preserves white matter integrity and cognitive function	42
Dopamine signaling modulates microglial NLRP3 inflammasome activation: implications for Parkinson’s disease	42
Microglial responses to peripheral type 1 interferon	42
Metabotropic glutamate receptor 5 inhibits α-synuclein-induced microglia inflammation to protect from neurotoxicity in Parkinson’s disease	42
Transcriptome profiling of long noncoding RNAs and mRNAs in spinal cord of a rat model of paclitaxel-induced peripheral neuropathy identifies potential mechanisms mediating neuroinflammation and pain	41
Spermidine reduces neuroinflammation and soluble amyloid beta in an Alzheimer’s disease mouse model	41
Social isolation induces neuroinflammation and microglia overactivation, while dihydromyricetin prevents and improves them	41
Microglial inflammation after chronic spinal cord injury is enhanced by reactive astrocytes via the fibronectin/β1 integrin pathway	41
Celastrol exerts a neuroprotective effect by directly binding to HMGB1 protein in cerebral ischemia–reperfusion	41
Comparisons of neuroinflammation, microglial activation, and degeneration of the locus coeruleus-norepinephrine system in APP/PS1 and aging mice	40
Fluoxetine inhibited the activation of A1 reactive astrocyte in a mouse model of major depressive disorder through astrocytic 5-HT2BR/β-arrestin2 pathway	40
Biologic TNF-α inhibitors reduce microgliosis, neuronal loss, and tau phosphorylation in a transgenic mouse model of tauopathy	40
Anti-inflammatory role of GM1 and other gangliosides on microglia	40
CCL2 is associated with microglia and macrophage recruitment in chronic traumatic encephalopathy	40
A crosstalk between gut and brain in sepsis-induced cognitive decline	40
Aging triggers an upregulation of a multitude of cytokines in the male and especially the female rodent hippocampus but more discrete changes in other brain regions	40
Neuroprotective epi-drugs quench the inflammatory response and microglial/macrophage activation in a mouse model of permanent brain ischemia	40
Maresin 1 promotes nerve regeneration and alleviates neuropathic pain after nerve injury	40
Asperosaponin VI ameliorates the CMS-induced depressive-like behaviors by inducing a neuroprotective microglial phenotype in hippocampus via PPAR-γ pathway	40
5-HT attenuates chronic stress-induced cognitive impairment in mice through intestinal flora disruption	38
Systemic inflammasome activation and pyroptosis associate with the progression of amnestic mild cognitive impairment and Alzheimer’s disease	38
X chromosome escapee genes are involved in ischemic sexual dimorphism through epigenetic modification of inflammatory signals	38
HMGB1 mediates synaptic loss and cognitive impairment in an animal model of sepsis-associated encephalopathy	38
Global, regional, and national burden of Guillain–Barré syndrome and its underlying causes from 1990 to 2019	38
Exercise suppresses neuroinflammation for alleviating Alzheimer’s disease	38
Recombinant CCL17-dependent CCR4 activation alleviates neuroinflammation and neuronal apoptosis through the PI3K/AKT/Foxo1 signaling pathway after ICH in mice	37
Interleukin-6 and YKL-40 predicted recurrent stroke after ischemic stroke or TIA: analysis of 6 inflammation biomarkers in a prospective cohort study	37
T-cell dysregulation is associated with disease severity in Parkinson’s Disease	37
The role of Th17 cells/IL-17A in AD, PD, ALS and the strategic therapy targeting on IL-17A	37
Early effects of LPS-induced neuroinflammation on the rat hippocampal glycolytic pathway	37
Treatment regimens for neuromyelitis optica spectrum disorder attacks: a retrospective cohort study	37
An RNA-sequencing transcriptome of the rodent Schwann cell response to peripheral nerve injury	37
Connexin 43 gap junction-mediated astrocytic network reconstruction attenuates isoflurane-induced cognitive dysfunction in mice	37
The immune response of T cells and therapeutic targets related to regulating the levels of T helper cells after ischaemic stroke	37
The reciprocal interactions between microglia and T cells in Parkinson’s disease: a double-edged sword	36
Acute systemic LPS-exposure impairs perivascular CSF distribution in mice	36
Anti-AQP4 autoantibodies promote ATP release from astrocytes and induce mechanical pain in rats	36
Deficiency of Nrf2 exacerbates white matter damage and microglia/macrophage levels in a mouse model of vascular cognitive impairment	36
Environmental noise stress disturbs commensal microbiota homeostasis and induces oxi-inflammmation and AD-like neuropathology through epithelial barrier disruption in the EOAD mouse model	36
Extracellular vesicles derived from mesenchymal stem cells alleviate neuroinflammation and mechanical allodynia in interstitial cystitis rats by inhibiting NLRP3 inflammasome activation	36
Blockade of the NLRP3/caspase-1 axis attenuates ketamine-induced hippocampus pyroptosis and cognitive impairment in neonatal rats	36
Hippocampal glucose uptake as a surrogate of metabolic change of microglia in Alzheimer’s disease	36
Minocycline reduces inflammatory response and cell death in a S100B retina degeneration model	36
Lysosomal acidification dysfunction in microglia: an emerging pathogenic mechanism of neuroinflammation and neurodegeneration	35
Glyphosate infiltrates the brain and increases pro-inflammatory cytokine TNFα: implications for neurodegenerative disorders	35

TGF-β1 signalling in Alzheimer’s pathology and cytoskeletal reorganization: a specialized Tau perspective	35
MicroRNA-22-3p ameliorates Alzheimer’s disease by targeting SOX9 through the NF-κB signaling pathway in the hippocampus	34
Chronic stress-induced depression requires the recruitment of peripheral Th17 cells into the brain	34
The cytokines interleukin-6 and interferon-α induce distinct microglia phenotypes	34
TRPV4 contributes to ER stress and inflammation: implications for Parkinson’s disease	34
Homer1 promotes the conversion of A1 astrocytes to A2 astrocytes and improves the recovery of transgenic mice after intracerebral hemorrhage	34
Increasing toll-like receptor 2 on astrocytes induced by Schwann cell-derived exosomes promotes recovery by inhibiting CSPGs deposition after spinal cord injury	34
Neuroinflammation, memory, and depression: new approaches to hippocampal neurogenesis	33
Pharmacological ablation of astrocytes reduces Aβ degradation and synaptic connectivity in an ex vivo model of Alzheimer’s disease	33
High-fat diet-induced diabetes leads to vascular alterations, pericyte reduction, and perivascular depletion of microglia in a 6-OHDA toxin model of Parkinson disease	33
Adenosine A3 receptor as a novel therapeutic target to reduce secondary events and improve neurocognitive functions following traumatic brain injury	33
Activated STAT3 signaling pathway by ligature-induced periodontitis could contribute to neuroinflammation and cognitive impairment in rats	33
IL-1β and TNF-α play an important role in modulating the risk of periodontitis and Alzheimer’s disease	33
Interleukin-6 actions in the hypothalamus protects against obesity and is involved in the regulation of neurogenesis	33
Plasma inflammatory cytokines and treatment-resistant depression with comorbid pain: improvement by ketamine	33
Functional characteristics of Th1, Th17, and ex-Th17 cells in EAE revealed by intravital two-photon microscopy	33
Can quantifying morphology and TMEM119 expression distinguish between microglia and infiltrating macrophages after ischemic stroke and reperfusion in male and female mice?	33
Ginsenoside Rb1 induces a pro-neurogenic microglial phenotype via PPARγ activation in male mice exposed to chronic mild stress	33
Phloretin suppresses neuroinflammation by autophagy-mediated Nrf2 activation in macrophages	33
Acute colitis during chronic experimental traumatic brain injury in mice induces dysautonomia and persistent extraintestinal, systemic, and CNS inflammation with exacerbated neurological deficits	33
Interactions of neuroimmune signaling and glutamate plasticity in addiction	32
Erbin protects against sepsis-associated encephalopathy by attenuating microglia pyroptosis via IRE1α/Xbp1s-Ca2+ axis	32
Brain injury, endothelial injury and inflammatory markers are elevated and express sex-specific alterations after COVID-19	32
Inhibition of heat shock protein family A member 8 attenuates spinal cord ischemia–reperfusion injury via astrocyte NF-κB/NLRP3 inflammasome pathway	32
Gut microbiota depletion by antibiotics ameliorates somatic neuropathic pain induced by nerve injury, chemotherapy, and diabetes in mice	32
Complement peptide C3a receptor 1 promotes optic nerve degeneration in DBA/2J mice	31
High-fat diet impairs duodenal barrier function and elicits glia-dependent changes along the gut-brain axis that are required for anxiogenic and depressive-like behaviors	31
Brain microglia activation and peripheral adaptive immunity in Parkinson’s disease: a multimodal PET study	31
Interleukin-10 deficiency exacerbates inflammation-induced tau pathology	31
Inflammatory neuronal loss in the substantia nigra induced by systemic lipopolysaccharide is prevented by knockout of the P2Y6 receptor in mice	31
Air pollution as a contributor to the inflammatory activity of multiple sclerosis	31
Interleukin-10 improves stroke outcome by controlling the detrimental Interleukin-17A response	31
Activation of GPR39 with TC-G 1008 attenuates neuroinflammation via SIRT1/PGC-1α/Nrf2 pathway post-neonatal hypoxic–ischemic injury in rats	31
A breakdown in microglial metabolic reprogramming causes internalization dysfunction of α-synuclein in a mouse model of Parkinson’s disease	31
The potential roles of m6A modification in regulating the inflammatory response in microglia	31
A selective inhibitor of the NLRP3 inflammasome as a potential therapeutic approach for neuroprotection in a transgenic mouse model of Huntington’s disease	31
TNF-α acutely enhances acid-sensing ion channel currents in rat dorsal root ganglion neurons via a p38 MAPK pathway	31
NOX2-mediated reactive oxygen species are double-edged swords in focal cerebral ischemia in mice	30
Neuroprotective effect of mitochondrial translocator protein ligand in a mouse model of tauopathy	30
Critical roles of sphingosine kinase 1 in the regulation of neuroinflammation and neuronal injury after spinal cord injury	30
Oxidative stress induced by NOX2 contributes to neuropathic pain via plasma membrane translocation of PKCε in rat dorsal root ganglion neurons	30
Glial activation is moderated by sex in response to amyloidosis but not to tau pathology in mouse models of neurodegenerative diseases	30
Macrophage elastase (MMP12) critically contributes to the development of subretinal fibrosis	30
Interleukin 13 promotes long-term recovery after ischemic stroke by inhibiting the activation of STAT3	30
EETs/sEHi alleviates nociception by blocking the crosslink between endoplasmic reticulum stress and neuroinflammation in a central poststroke pain model	30
Downregulating expression of OPTN elevates neuroinflammation via AIM2 inflammasome- and RIPK1-activating mechanisms in APP/PS1 transgenic mice	30
Recruitment of γδ T cells to the lesion via the CCL2/CCR2 signaling after spinal cord injury	30
A tale of two transmitters: serotonin and histamine as in vivo biomarkers of chronic stress in mice	29
Effects of diabetes on microglial physiology: a systematic review of in vitro, preclinical and clinical studies	29
Rapid morphologic changes to microglial cells and upregulation of mixed microglial activation state markers induced by P2X7 receptor stimulation and increased intraocular pressure	29
Gut microbiota, circulating cytokines and dementia: a Mendelian randomization study	29
Beyond the lesion site: minocycline augments inflammation and anxiety-like behavior following SCI in rats through action on the gut microbiota	29
Pyruvate kinase isoform M2 impairs cognition in systemic lupus erythematosus by promoting microglial synaptic pruning via the β-catenin signaling pathway	29
HMGB1 mediates cognitive impairment caused by the NLRP3 inflammasome in the late stage of traumatic brain injury	29
Administration of Maresin-1 ameliorates the physiopathology of experimental autoimmune encephalomyelitis	29
Berberine ameliorates depression-like behaviors in mice via inhibiting NLRP3 inflammasome-mediated neuroinflammation and preventing neuroplasticity disruption	29
Capsazepine decreases corneal pain syndrome in severe dry eye disease	29
PD-L1 signaling in reactive astrocytes counteracts neuroinflammation and ameliorates neuronal damage after traumatic brain injury	28
Calcitonin gene-related peptide regulates spinal microglial activation through the histone H3 lysine 27 trimethylation via enhancer of zeste homolog-2 in rats with neuropathic pain	28
The role of S100B/RAGE-enhanced ADAM17 activation in endothelial glycocalyx shedding after traumatic brain injury	28
TGR5 activation attenuates neuroinflammation via Pellino3 inhibition of caspase-8/NLRP3 after middle cerebral artery occlusion in rats	28
Suppression of TLR4-MyD88 signaling pathway attenuated chronic mechanical pain in a rat model of endometriosis	28
Macrophages in close proximity to the vitreoretinal interface are potential biomarkers of inflammation during retinal vascular disease	28
Interleukin-1 blockade attenuates white matter inflammation and oligodendrocyte loss after progressive systemic lipopolysaccharide exposure in near-term fetal sheep	28
Alzheimer’s disease-related transcriptional sex differences in myeloid cells	28
Nilotinib modulates LPS-induced cognitive impairment and neuroinflammatory responses by regulating P38/STAT3 signaling	28
Systemic administration of β-glucan induces immune training in microglia	28
Activation of locus coeruleus-spinal cord noradrenergic neurons alleviates neuropathic pain in mice via reducing neuroinflammation from astrocytes and microglia in spinal dorsal horn	28
Complete spatial characterisation of N-glycosylation upon striatal neuroinflammation in the rodent brain	27
miR-142 downregulation alleviates rat PTSD-like behaviors, reduces the level of inflammatory cytokine expression and apoptosis in hippocampus, and upregulates the expression of fragile X mental retard	27
Anti-NMDAR encephalitis induced in mice by active immunization with a peptide from the amino-terminal domain of the GluN1 subunit	27
Astrocytic Nrf2 expression protects spinal cord from oxidative stress following spinal cord injury in a male mouse model	27
Tissue-resident M2 macrophages directly contact primary sensory neurons in the sensory ganglia after nerve injury	27
Chronic exposure to IL-6 induces a desensitized phenotype of the microglia	27
Human umbilical cord-derived mesenchymal stem cell transplantation supplemented with curcumin improves the outcomes of ischemic stroke via AKT/GSK-3β/β-TrCP/Nrf2 axis	27
Autoantibody screening in Guillain–Barré syndrome	27
Fundamentally different roles of neuronal TNF receptors in CNS pathology: TNFR1 and IKKβ promote microglial responses and tissue injury in demyelination while TNFR2 protects against excitotoxicity in	27
Headache and immunological/autoimmune disorders: a comprehensive review of available epidemiological evidence with insights on potential underlying mechanisms	27
H3K18 lactylation of senescent microglia potentiates brain aging and Alzheimer's disease through the NFκB signaling pathway	27
Altered substrate metabolism in neurodegenerative disease: new insights from metabolic imaging	27
Aicardi-Goutières syndrome-associated mutation at ADAR1 gene locus activates innate immune response in mouse brain	27
Lipocalin-2-mediated astrocyte pyroptosis promotes neuroinflammatory injury via NLRP3 inflammasome activation in cerebral ischemia/reperfusion injury	26
Activation of MC1R with BMS-470539 attenuates neuroinflammation via cAMP/PKA/Nurr1 pathway after neonatal hypoxic-ischemic brain injury in rats	26
Fatty acids role in multiple sclerosis as “metabokines”	26
Inhibition of microglia overactivation restores neuronal survival in a mouse model of CDKL5 deficiency disorder	26
Acute IL-1RA treatment suppresses the peripheral and central inflammatory response to spinal cord injury	26
Human Huntington’s disease pluripotent stem cell-derived microglia develop normally but are abnormally hyper-reactive and release elevated levels of reactive oxygen species	26
Indole-3-carbinol regulates microglia homeostasis and protects the retina from degeneration	25
Age-dependent favorable visual recovery despite significant retinal atrophy in pediatric MOGAD: how much retina do you really need to see well?	25
Endothelial glycocalyx in traumatic brain injury associated coagulopathy: potential mechanisms and impact	25
Gas6 induces inflammation and reduces plaque burden but worsens behavior in a sex-dependent manner in the APP/PS1 model of Alzheimer’s disease	25
Deficiency of microglial Hv1 channel is associated with activation of autophagic pathway and ROS production in LPC-induced demyelination mouse model	25
LncRNA HOXA-AS2 regulates microglial polarization via recruitment of PRC2 and epigenetic modification of PGC-1α expression	25
Patchouli alcohol attenuates the cognitive deficits in a transgenic mouse model of Alzheimer’s disease via modulating neuropathology and gut microbiota through suppressing C/EBPβ/AEP pathway	25
Ultrastructural characterization of dark microglia during aging in a mouse model of Alzheimer’s disease pathology and in human post-mortem brain samples	25