Journal of Neuroinflammation

Article	Citations
The semantics of microglia activation: neuroinflammation, homeostasis, and stress	197
Central nervous system complications associated with SARS-CoV-2 infection: integrative concepts of pathophysiology and case reports	188
Inflammation after spinal cord injury: a review of the critical timeline of signaling cues and cellular infiltration	161
TREM2 activation attenuates neuroinflammation and neuronal apoptosis via PI3K/Akt pathway after intracerebral hemorrhage in mice	150
Edaravone ameliorates depressive and anxiety-like behaviors via Sirt1/Nrf2/HO-1/Gpx4 pathway	143
The good, the bad, and the opportunities of the complement system in neurodegenerative disease	134
The association of neutrophil to lymphocyte ratio, platelet to lymphocyte ratio, and lymphocyte to monocyte ratio with post-thrombolysis early neurological outcomes in patients with acute ischemic str	134
The NLRP3 inflammasome in traumatic brain injury: potential as a biomarker and therapeutic target	129
Isoliquiritin ameliorates depression by suppressing NLRP3-mediated pyroptosis via miRNA-27a/SYK/NF-κB axis	126
Mer regulates microglial/macrophage M1/M2 polarization and alleviates neuroinflammation following traumatic brain injury	122
Microglia in depression: an overview of microglia in the pathogenesis and treatment of depression	122
The relationships between neuroinflammation, beta-amyloid and tau deposition in Alzheimer’s disease: a longitudinal PET study	119
A primary neural cell culture model to study neuron, astrocyte, and microglia interactions in neuroinflammation	117
Cellular infiltration in traumatic brain injury	115
β-Hydroxybutyrate inhibits inflammasome activation to attenuate Alzheimer’s disease pathology	114
Neuromyelitis optica spectrum disorders: from pathophysiology to therapeutic strategies	109
Astrocytes have the capacity to act as antigen-presenting cells in the Parkinson’s disease brain	106
Cottonseed oil alleviates ischemic stroke injury by inhibiting the inflammatory activation of microglia and astrocyte	106
Ingestion of Lactobacillus intestinalis and Lactobacillus reuteri causes depression- and anhedonia-like phenotypes in antibiotic-treated mice via the vagus nerve	106
Microglia induce the transformation of A1/A2 reactive astrocytes via the CXCR7/PI3K/Akt pathway in chronic post-surgical pain	103
Inhibiting HMGB1-RAGE axis prevents pro-inflammatory macrophages/microglia polarization and affords neuroprotection after spinal cord injury	102
NLRP1 inflammasome contributes to chronic stress-induced depressive-like behaviors in mice	101
FGF21 alleviates neuroinflammation following ischemic stroke by modulating the temporal and spatial dynamics of microglia/macrophages	96
Aucubin alleviates oxidative stress and inflammation via Nrf2-mediated signaling activity in experimental traumatic brain injury	96
Transcriptomic profiling of microglia and astrocytes throughout aging	96

NAD+ improves cognitive function and reduces neuroinflammation by ameliorating mitochondrial damage and decreasing ROS production in chronic cerebral hypoperfusion models through Sirt1/PGC-1α pathway	94
Associations between gut microbiota and Alzheimer’s disease, major depressive disorder, and schizophrenia	93
Low-density lipoprotein receptor (LDLR) regulates NLRP3-mediated neuronal pyroptosis following cerebral ischemia/reperfusion injury	92
Uncovering sex differences of rodent microglia	91
Cerebrospinal fluid findings in COVID-19: a multicenter study of 150 lumbar punctures in 127 patients	86
Rifaximin-mediated gut microbiota regulation modulates the function of microglia and protects against CUMS-induced depression-like behaviors in adolescent rat	84
On inflammatory hypothesis of depression: what is the role of IL-6 in the middle of the chaos?	82
CD36-mediated uptake of myelin debris by macrophages and microglia reduces neuroinflammation	82
Rutin prevents tau pathology and neuroinflammation in a mouse model of Alzheimer’s disease	82
Astrocytic and microglial cells as the modulators of neuroinflammation in Alzheimer’s disease	82
The relationship between inflammation and neurocognitive dysfunction in obstructive sleep apnea syndrome	82
Annexin A1 protects against cerebral ischemia–reperfusion injury by modulating microglia/macrophage polarization via FPR2/ALX-dependent AMPK-mTOR pathway	81
Crosstalk between astrocytes and microglia results in increased degradation of α-synuclein and amyloid-β aggregates	80
High-frequency repetitive transcranial magnetic stimulation improves functional recovery by inhibiting neurotoxic polarization of astrocytes in ischemic rats	79
A1 astrocytes contribute to murine depression-like behavior and cognitive dysfunction, which can be alleviated by IL-10 or fluorocitrate treatment	78
Tanshinone IIA attenuates neuroinflammation via inhibiting RAGE/NF-κB signaling pathway in vivo and in vitro	77
Sirtuin 3 protects against anesthesia/surgery-induced cognitive decline in aged mice by suppressing hippocampal neuroinflammation	76
Tryptophan-kynurenine metabolism: a link between the gut and brain for depression in inflammatory bowel disease	76
BDNF reverses aging-related microglial activation	76
NK cell-derived exosomes carry miR-207 and alleviate depression-like symptoms in mice	75
Stroke-induced immunosuppression: implications for the prevention and prediction of post-stroke infections	74
Microglia and macrophage exhibit attenuated inflammatory response and ferroptosis resistance after RSL3 stimulation via increasing Nrf2 expression	74
Anti-inflammatory protein TSG-6 secreted by bone marrow mesenchymal stem cells attenuates neuropathic pain by inhibiting the TLR2/MyD88/NF-κB signaling pathway in spinal microglia	74
Cerebrospinal fluid findings in patients with myelin oligodendrocyte glycoprotein (MOG) antibodies. Part 1: Results from 163 lumbar punctures in 100 adult patients	73
Early glycolytic reprogramming controls microglial inflammatory activation	72
Glioblastoma hijacks microglial gene expression to support tumor growth	72
Exosomes derived from bone-marrow mesenchymal stem cells alleviate cognitive decline in AD-like mice by improving BDNF-related neuropathology	71
Microglial activation contributes to cognitive impairments in rotenone-induced mouse Parkinson’s disease model	70
Stimulator of IFN genes mediates neuroinflammatory injury by suppressing AMPK signal in experimental subarachnoid hemorrhage	69
The role of Toll-like receptors and neuroinflammation in Parkinson’s disease	68
Neurological consequences of COVID-19: what have we learned and where do we go from here?	67
Iron overload contributes to general anaesthesia-induced neurotoxicity and cognitive deficits	66
Microglial physiological properties and interactions with synapses are altered at presymptomatic stages in a mouse model of Huntington’s disease pathology	66
The peri-menopause in a woman’s life: a systemic inflammatory phase that enables later neurodegenerative disease	65
Stress-induced NLRP3 inflammasome activation negatively regulates fear memory in mice	64
Cellular senescence in the aging retina and developments of senotherapies for age-related macular degeneration	63
Astragaloside IV inhibits astrocyte senescence: implication in Parkinson’s disease	63
MAPK signaling determines lysophosphatidic acid (LPA)-induced inflammation in microglia	63
Intermittent theta-burst stimulation improves motor function by inhibiting neuronal pyroptosis and regulating microglial polarization via TLR4/NFκB/NLRP3 signaling pathway in cerebral ischemic mice	61
Dihydrolipoic acid protects against lipopolysaccharide-induced behavioral deficits and neuroinflammation via regulation of Nrf2/HO-1/NLRP3 signaling in rat	61
Therapeutic Trem2 activation ameliorates amyloid-beta deposition and improves cognition in the 5XFAD model of amyloid deposition	59
The NLRP3 inflammasome: an emerging therapeutic target for chronic pain	58
Activating cGAS–STING axis contributes to neuroinflammation in CVST mouse model and induces inflammasome activation and microglia pyroptosis	58
25-Hydroxycholesterol amplifies microglial IL-1β production in an apoE isoform-dependent manner	57
TAK1 mediates neuronal pyroptosis in early brain injury after subarachnoid hemorrhage	56
Role of inflammasomes in multiple sclerosis and their potential as therapeutic targets	56
Dimethyl itaconate, an itaconate derivative, exhibits immunomodulatory effects on neuroinflammation in experimental autoimmune encephalomyelitis	56
Microglial deletion and inhibition alleviate behavior of post-traumatic stress disorder in mice	55
Meta-analysis of mouse transcriptomic studies supports a context-dependent astrocyte reaction in acute CNS injury versus neurodegeneration	55
TREM2 ectodomain and its soluble form in Alzheimer’s disease	54

Hippocampal microglial activation triggers a neurotoxic-specific astrocyte response and mediates etomidate-induced long-term synaptic inhibition	54
Macrophage to myofibroblast transition contributes to subretinal fibrosis secondary to neovascular age-related macular degeneration	53
LncGBP9/miR-34a axis drives macrophages toward a phenotype conducive for spinal cord injury repair via STAT1/STAT6 and SOCS3	53
NLRP3 inflammasome-mediated microglial pyroptosis is critically involved in the development of post-cardiac arrest brain injury	53
T cell infiltration and upregulation of MHCII in microglia leads to accelerated neuronal loss in an α-synuclein rat model of Parkinson’s disease	53
Central nervous system macrophages in progressive multiple sclerosis: relationship to neurodegeneration and therapeutics	53
Anti-inflammatory IL-10 administration rescues depression-associated learning and memory deficits in mice	52
27-Hydroxycholesterol contributes to cognitive deficits in APP/PS1 transgenic mice through microbiota dysbiosis and intestinal barrier dysfunction	52
Relevant mediators involved in and therapies targeting the inflammatory response induced by activation of the NLRP3 inflammasome in ischemic stroke	51
Glycine, the smallest amino acid, confers neuroprotection against d-galactose-induced neurodegeneration and memory impairment by regulating c-Jun N-terminal kinase in the mouse brain	51
Sestrin2 regulates microglia polarization through mTOR-mediated autophagic flux to attenuate inflammation during experimental brain ischemia	51
Microglia as target for anti-inflammatory approaches to prevent secondary brain injury after subarachnoid hemorrhage (SAH)	51
Chronic colitis exacerbates NLRP3-dependent neuroinflammation and cognitive impairment in middle-aged brain	50
Ceria nanoparticles ameliorate white matter injury after intracerebral hemorrhage: microglia-astrocyte involvement in remyelination	50
Engagement of TREM2 by a novel monoclonal antibody induces activation of microglia and improves cognitive function in Alzheimer’s disease models	50
Neuroinflammation is associated with infiltration of T cells in Lewy body disease and α-synuclein transgenic models	49
The effect of insomnia on development of Alzheimer’s disease	48
Exogenous activation of cannabinoid-2 receptor modulates TLR4/MMP9 expression in a spinal cord ischemia reperfusion rat model	48
Neuroinflammatory mechanisms of post-traumatic epilepsy	48
CD4+ effector T cells accelerate Alzheimer’s disease in mice	48
SARS-CoV-2 productively infects human brain microvascular endothelial cells	47
Effects of advanced age upon astrocyte-specific responses to acute traumatic brain injury in mice	47
Fluoxetine regulates eEF2 activity (phosphorylation) via HDAC1 inhibitory mechanism in an LPS-induced mouse model of depression	47
Sodium para-aminosalicylic acid inhibits manganese-induced NLRP3 inflammasome-dependent pyroptosis by inhibiting NF-κB pathway activation and oxidative stress	46
CX3CL1/CX3CR1 axis attenuates early brain injury via promoting the delivery of exosomal microRNA-124 from neuron to microglia after subarachnoid hemorrhage	46
Role of sex and high-fat diet in metabolic and hypothalamic disturbances in the 3xTg-AD mouse model of Alzheimer’s disease	46
Specific depletion of resident microglia in the early stage of stroke reduces cerebral ischemic damage	46
Lipocalin 2 induces neuroinflammation and blood-brain barrier dysfunction through liver-brain axis in murine model of nonalcoholic steatohepatitis	45
Microglial amyloid beta clearance is driven by PIEZO1 channels	45
Irisin ameliorates neuroinflammation and neuronal apoptosis through integrin αVβ5/AMPK signaling pathway after intracerebral hemorrhage in mice	45
CCL3 contributes to secondary damage after spinal cord injury	44
Potential caveats of putative microglia-specific markers for assessment of age-related cerebrovascular neuroinflammation	44
Serum GFAP and NfL as disease severity and prognostic biomarkers in patients with aquaporin-4 antibody-positive neuromyelitis optica spectrum disorder	44
miR-19a/b-3p promotes inflammation during cerebral ischemia/reperfusion injury via SIRT1/FoxO3/SPHK1 pathway	44
Single-cell transcriptomic analysis of the immune cell landscape in the aged mouse brain after ischemic stroke	44
MicroRNA-195 prevents hippocampal microglial/macrophage polarization towards the M1 phenotype induced by chronic brain hypoperfusion through regulating CX3CL1/CX3CR1 signaling	44
Activation of the executioner caspases-3 and -7 promotes microglial pyroptosis in models of multiple sclerosis	43
Long-term running exercise improves cognitive function and promotes microglial glucose metabolism and morphological plasticity in the hippocampus of APP/PS1 mice	43
Forsythoside B attenuates memory impairment and neuroinflammation via inhibition on NF-κB signaling in Alzheimer’s disease	43
Microglial and peripheral immune priming is partially sexually dimorphic in adolescent mouse offspring exposed to maternal high-fat diet	43
Expression of SARS-CoV-2-related receptors in cells of the neurovascular unit: implications for HIV-1 infection	42
ALS monocyte-derived microglia-like cells reveal cytoplasmic TDP-43 accumulation, DNA damage, and cell-specific impairment of phagocytosis associated with disease progression	42
Cordycepin confers long-term neuroprotection via inhibiting neutrophil infiltration and neuroinflammation after traumatic brain injury	42
Resveratrol mediates mechanical allodynia through modulating inflammatory response via the TREM2-autophagy axis in SNI rat model	42
Microglia depletion fails to abrogate inflammation-induced sickness in mice and rats	42
Kynurenine pathway modulation reverses the experimental autoimmune encephalomyelitis mouse disease progression	41
Microbial BMAA elicits mitochondrial dysfunction, innate immunity activation, and Alzheimer’s disease features in cortical neurons	41
P2X7R-mediated autophagic impairment contributes to central sensitization in a chronic migraine model with recurrent nitroglycerin stimulation in mice	41
IC100: a novel anti-ASC monoclonal antibody improves functional outcomes in an animal model of multiple sclerosis	41
Mechanistic insights into the role of the chemokine CCL2/CCR2 axis in dorsal root ganglia to peripheral inflammation and pain hypersensitivity	41
Astrocytic A1/A2 paradigm participates in glycogen mobilization mediated neuroprotection on reperfusion injury after ischemic stroke	41
Three-dimensional morphometric analysis reveals time-dependent structural changes in microglia and astrocytes in the central amygdala and hypothalamic paraventricular nucleus of heart failure rats	41
Deficiency of the microglial Hv1 proton channel attenuates neuronal pyroptosis and inhibits inflammatory reaction after spinal cord injury	41
Traumatic brain injury results in unique microglial and astrocyte transcriptomes enriched for type I interferon response	41
Oral P. gingivalis impairs gut permeability and mediates immune responses associated with neurodegeneration in LRRK2 R1441G mice	41
Targeting connexin 43 provides anti-inflammatory effects after intracerebral hemorrhage injury by regulating YAP signaling	41
Neurotransmitter and neuropeptide regulation of mast cell function: a systematic review	41
Molecular mimicry of NMDA receptors may contribute to neuropsychiatric symptoms in severe COVID-19 cases	41
The immune system on the TRAIL of Alzheimer’s disease	41
Cerebrospinal fluid findings in patients with myelin oligodendrocyte glycoprotein (MOG) antibodies. Part 2: Results from 108 lumbar punctures in 80 pediatric patients	40
High-fat diet exacerbates cognitive decline in mouse models of Alzheimer's disease and mixed dementia in a sex-dependent manner	40
NLRP3 inhibition attenuates early brain injury and delayed cerebral vasospasm after subarachnoid hemorrhage	40
Astrocyte remodeling in the beneficial effects of long-term voluntary exercise in Alzheimer’s disease	40
The overexpression of TDP-43 in astrocytes causes neurodegeneration via a PTP1B-mediated inflammatory response	40
Emerging role of STING signalling in CNS injury: inflammation, autophagy, necroptosis, ferroptosis and pyroptosis	39
The CD200/CD200R signaling pathway contributes to spontaneous functional recovery by enhancing synaptic plasticity after stroke	38
Interleukin-9 regulates macrophage activation in the progressive multiple sclerosis brain	38
Age-dependent involvement of gut mast cells and histamine in post-stroke inflammation	38
Dysregulated phosphoinositide 3-kinase signaling in microglia: shaping chronic neuroinflammation	38
Metabotropic glutamate receptor 5 inhibits α-synuclein-induced microglia inflammation to protect from neurotoxicity in Parkinson’s disease	38
Microglial inflammation after chronic spinal cord injury is enhanced by reactive astrocytes via the fibronectin/β1 integrin pathway	38
Interleukin-1β mediates alterations in mitochondrial fusion/fission proteins and memory impairment induced by amyloid-β oligomers	38
Functions of resolvin D1-ALX/FPR2 receptor interaction in the hemoglobin-induced microglial inflammatory response and neuronal injury	38
Acute inflammatory profiles differ with sex and age after spinal cord injury	37
Exploration of anti-inflammatory mechanism of forsythiaside A and forsythiaside B in CuSO4-induced inflammation in zebrafish by metabolomic and proteomic analyses	37
Pinocembrin ameliorates intermittent hypoxia-induced neuroinflammation through BNIP3-dependent mitophagy in a murine model of sleep apnea	37
p38-TFEB pathways promote microglia activation through inhibiting CMA-mediated NLRP3 degradation in Parkinson's disease	36
Transgenic inhibition of astroglial NF-κB restrains the neuroinflammatory and neurodegenerative outcomes of experimental mouse glaucoma	36
Photobiomodulation inhibits the activation of neurotoxic microglia and astrocytes by inhibiting Lcn2/JAK2-STAT3 crosstalk after spinal cord injury in male rats	36
NF-κB p65-dependent transcriptional regulation of histone deacetylase 2 contributes to the chronic constriction injury-induced neuropathic pain via the microRNA-183/TXNIP/NLRP3 axis	36

Inflammatory resolution and vascular barrier restoration after retinal ischemia reperfusion injury	36
Neuroinflammation as an etiological trigger for depression comorbid with inflammatory bowel disease	36
COVID-19 and cognitive impairment: neuroinvasive and blood‒brain barrier dysfunction	36
Attenuating vascular stenosis-induced astrogliosis preserves white matter integrity and cognitive function	36
Mechanisms underlying antidepressant effect of transcutaneous auricular vagus nerve stimulation on CUMS model rats based on hippocampal α7nAchR/NF-κB signal pathway	36
Transcriptome profiling of long noncoding RNAs and mRNAs in spinal cord of a rat model of paclitaxel-induced peripheral neuropathy identifies potential mechanisms mediating neuroinflammation and pain	36
Aggravated brain injury after neonatal hypoxic ischemia in microglia-depleted mice	36
IL-33 and its decoy sST2 in patients with Alzheimer’s disease and mild cognitive impairment	36
Mitophagy in neurological disorders	35
Microglial responses to peripheral type 1 interferon	35
CCL2 is associated with microglia and macrophage recruitment in chronic traumatic encephalopathy	35
TRPV4-induced Müller cell gliosis and TNF-α elevation-mediated retinal ganglion cell apoptosis in glaucomatous rats via JAK2/STAT3/NF-κB pathway	35
A1 reactive astrocytes and a loss of TREM2 are associated with an early stage of pathology in a mouse model of cerebral amyloid angiopathy	35
Independent risk factors for myasthenic crisis and disease exacerbation in a retrospective cohort of myasthenia gravis patients	35
X chromosome escapee genes are involved in ischemic sexual dimorphism through epigenetic modification of inflammatory signals	35
Extrasynaptic CaMKIIα is involved in the antidepressant effects of ketamine by downregulating GluN2B receptors in an LPS-induced depression model	35
MicroRNA-155-5p promotes neuroinflammation and central sensitization via inhibiting SIRT1 in a nitroglycerin-induced chronic migraine mouse model	35
Aging triggers an upregulation of a multitude of cytokines in the male and especially the female rodent hippocampus but more discrete changes in other brain regions	35
Neuroprotective epi-drugs quench the inflammatory response and microglial/macrophage activation in a mouse model of permanent brain ischemia	35
Interplay between Müller cells and microglia aggravates retinal inflammatory response in experimental glaucoma	35
IRE1α inhibition attenuates neuronal pyroptosis via miR-125/NLRP1 pathway in a neonatal hypoxic-ischemic encephalopathy rat model	34
Hyperphosphorylated tau mediates neuronal death by inducing necroptosis and inflammation in Alzheimer’s disease	34
ProBDNF promotes sepsis-associated encephalopathy in mice by dampening the immune activity of meningeal CD4+ T cells	34
CXCR5 down-regulation alleviates cognitive dysfunction in a mouse model of sepsis-associated encephalopathy: potential role of microglial autophagy and the p38MAPK/NF-κB/STAT3 signaling pathway	34
Neuroprotective effects of verbascoside against Alzheimer’s disease via the relief of endoplasmic reticulum stress in Aβ-exposed U251 cells and APP/PS1 mice	34
Comparisons of neuroinflammation, microglial activation, and degeneration of the locus coeruleus-norepinephrine system in APP/PS1 and aging mice	34
GM-CSF induces noninflammatory proliferation of microglia and disturbs electrical neuronal network rhythms in situ	34
Mitigation of helium irradiation-induced brain injury by microglia depletion	34
The prenatal challenge with lipopolysaccharide and polyinosinic:polycytidylic acid disrupts CX3CL1-CX3CR1 and CD200-CD200R signalling in the brains of male rat offspring: a link to schizophrenia-like	34
Neuroprotective effect of astrocyte-derived IL-33 in neonatal hypoxic-ischemic brain injury	33
DKK3 ameliorates neuropathic pain via inhibiting ASK-1/JNK/p-38-mediated microglia polarization and neuroinflammation	33
Microglia knockdown reduces inflammation and preserves cognition in diabetic animals after experimental stroke	33
Divanillyl sulfone suppresses NLRP3 inflammasome activation via inducing mitophagy to ameliorate chronic neuropathic pain in mice	33
Tauroursodeoxycholic acid alleviates secondary injury in spinal cord injury mice by reducing oxidative stress, apoptosis, and inflammatory response	33
The function of gut microbiota in immune-related neurological disorders: a review	33
Repopulation of T, B, and NK cells following alemtuzumab treatment in relapsing-remitting multiple sclerosis	33
Gut microbiota is causally associated with poststroke cognitive impairment through lipopolysaccharide and butyrate	33
Caspase-1 has a critical role in blood-brain barrier injury and its inhibition contributes to multifaceted repair	33
PET measurement of cyclooxygenase-2 using a novel radioligand: upregulation in primate neuroinflammation and first-in-human study	33
The cerebrovascular and neurological impact of chronic smoking on post-traumatic brain injury outcome and recovery: an in vivo study	33
Social isolation induces neuroinflammation and microglia overactivation, while dihydromyricetin prevents and improves them	33
Neuroinflammation represents a common theme amongst genetic and environmental risk factors for Alzheimer and Parkinson diseases	33
Suppression of histone deacetylases by SAHA relieves bone cancer pain in rats via inhibiting activation of glial cells in spinal dorsal horn and dorsal root ganglia	33
Microglia and astrocyte involvement in neurodegeneration and brain cancer	33
TDP-43 mediated blood-brain barrier permeability and leukocyte infiltration promote neurodegeneration in a low-grade systemic inflammation mouse model	32
Celastrol exerts a neuroprotective effect by directly binding to HMGB1 protein in cerebral ischemia–reperfusion	32
Systemic inflammasome activation and pyroptosis associate with the progression of amnestic mild cognitive impairment and Alzheimer’s disease	32
DSS-induced inflammation in the colon drives a proinflammatory signature in the brain that is ameliorated by prophylactic treatment with the S100A9 inhibitor paquinimod	32
Recombinant CCL17-dependent CCR4 activation alleviates neuroinflammation and neuronal apoptosis through the PI3K/AKT/Foxo1 signaling pathway after ICH in mice	32
Two forms of CX3CL1 display differential activity and rescue cognitive deficits in CX3CL1 knockout mice	32
Sepsis-associated brain injury: underlying mechanisms and potential therapeutic strategies for acute and long-term cognitive impairments	32
Small extracellular vesicles encapsulating CCL2 from activated astrocytes induce microglial activation and neuronal apoptosis after traumatic spinal cord injury	32
Spotlight on pyroptosis: role in pathogenesis and therapeutic potential of ocular diseases	32
Adenosine A3 receptor as a novel therapeutic target to reduce secondary events and improve neurocognitive functions following traumatic brain injury	32
Anti-inflammatory role of GM1 and other gangliosides on microglia	32
Chronic alcohol-induced neuroinflammation involves CCR2/5-dependent peripheral macrophage infiltration and microglia alterations	31
Thrombomodulin facilitates peripheral nerve regeneration through regulating M1/M2 switching	31
Intermittent fasting reduces neuroinflammation in intracerebral hemorrhage through the Sirt3/Nrf2/HO-1 pathway	31
Minocycline reduces inflammatory response and cell death in a S100B retina degeneration model	31
Treatment regimens for neuromyelitis optica spectrum disorder attacks: a retrospective cohort study	31
Metabolic reprogramming mediates hippocampal microglial M1 polarization in response to surgical trauma causing perioperative neurocognitive disorders	31
Nuclear factor kappa B activation appears weaker in schizophrenia patients with high brain cytokines than in non-schizophrenic controls with high brain cytokines	31
MCC950, a selective NLPR3 inflammasome inhibitor, improves neurologic function and survival after cardiac arrest and resuscitation	31
Spermidine reduces neuroinflammation and soluble amyloid beta in an Alzheimer’s disease mouse model	31
Association of inflammatory markers with cerebral small vessel disease in community-based population	31
The role of the adaptive immune system and T cell dysfunction in neurodegenerative diseases	31
Microglia dynamics in adolescent traumatic brain injury	31
Environmental noise stress disturbs commensal microbiota homeostasis and induces oxi-inflammmation and AD-like neuropathology through epithelial barrier disruption in the EOAD mouse model	30
GSK872 and necrostatin-1 protect retinal ganglion cells against necroptosis through inhibition of RIP1/RIP3/MLKL pathway in glutamate-induced retinal excitotoxic model of glaucoma	30
Epigenetic regulation of innate immune memory in microglia	30
Hippocampal glucose uptake as a surrogate of metabolic change of microglia in Alzheimer’s disease	30
Blockade of the NLRP3/caspase-1 axis attenuates ketamine-induced hippocampus pyroptosis and cognitive impairment in neonatal rats	30
Effects of long-term and brain-wide colonization of peripheral bone marrow-derived myeloid cells in the CNS	30
Acute systemic LPS-exposure impairs perivascular CSF distribution in mice	30
Knockdown of long non-coding RNA SOX2OT downregulates SOX2 to improve hippocampal neurogenesis and cognitive function in a mouse model of sepsis-associated encephalopathy	30
TREM2 activation alleviates neural damage via Akt/CREB/BDNF signalling after traumatic brain injury in mice	30
Can quantifying morphology and TMEM119 expression distinguish between microglia and infiltrating macrophages after ischemic stroke and reperfusion in male and female mice?	29
Deficiency of Nrf2 exacerbates white matter damage and microglia/macrophage levels in a mouse model of vascular cognitive impairment	29
Interleukin-6 and YKL-40 predicted recurrent stroke after ischemic stroke or TIA: analysis of 6 inflammation biomarkers in a prospective cohort study	29
The macrophage: a key player in the pathophysiology of peripheral neuropathies	29
High-fat diet-induced diabetes leads to vascular alterations, pericyte reduction, and perivascular depletion of microglia in a 6-OHDA toxin model of Parkinson disease	29
Extracellular vesicles derived from mesenchymal stem cells alleviate neuroinflammation and mechanical allodynia in interstitial cystitis rats by inhibiting NLRP3 inflammasome activation	29
Microglial burden, activation and dystrophy patterns in frontotemporal lobar degeneration	29
Acute colitis during chronic experimental traumatic brain injury in mice induces dysautonomia and persistent extraintestinal, systemic, and CNS inflammation with exacerbated neurological deficits	29
Functional characteristics of Th1, Th17, and ex-Th17 cells in EAE revealed by intravital two-photon microscopy	29
Phloretin suppresses neuroinflammation by autophagy-mediated Nrf2 activation in macrophages	28
The circadian clock protein Rev-erbα provides neuroprotection and attenuates neuroinflammation against Parkinson’s disease via the microglial NLRP3 inflammasome	28
Systemic administration of β-glucan induces immune training in microglia	28
A selective inhibitor of the NLRP3 inflammasome as a potential therapeutic approach for neuroprotection in a transgenic mouse model of Huntington’s disease	28
Biologic TNF-α inhibitors reduce microgliosis, neuronal loss, and tau phosphorylation in a transgenic mouse model of tauopathy	28
TNF-α acutely enhances acid-sensing ion channel currents in rat dorsal root ganglion neurons via a p38 MAPK pathway	28
A crosstalk between gut and brain in sepsis-induced cognitive decline	28
TRPV4 contributes to ER stress and inflammation: implications for Parkinson’s disease	28
The role of Th17 cells/IL-17A in AD, PD, ALS and the strategic therapy targeting on IL-17A	28
Evaluation of M2-like macrophage enrichment after diffuse traumatic brain injury through transient interleukin-4 expression from engineered mesenchymal stromal cells	28