OOIR: Observatory of International Research

Papers

(The H4-Index of Journal of Neuroinflammation is 64. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-05-01 to 2025-05-01.)

Article	Citations
Correction: Smek1 deficiency exacerbates experimental autoimmune encephalomyelitis by activating proinflammatory microglia and suppressing the IDO1-AhR pathway	425
Fractalkine isoforms differentially regulate microglia-mediated inflammation and enhance visual function in the diabetic retina	319
Regulation of the p75 neurotrophin receptor attenuates neuroinflammation and stimulates hippocampal neurogenesis in experimental Streptococcus pneumoniae meningitis	296
Correction to: Vagus nerve stimulation modulates hippocampal inflammation caused by continuous stress in rats	279
Intrauterine inflammation and postnatal intravenous dopamine alter the neurovascular unit in preterm newborn lambs	239
Extracellular vesicles produced by HIV-1 Nef-expressing cells induce myelin impairment and oligodendrocyte damage in the mouse central nervous system	196
Argonaute-2 protects the neurovascular unit from damage caused by systemic inflammation	176
Inhibition of neutrophil extracellular traps alleviates blood–brain barrier disruption and cognitive dysfunction via Wnt3/β-catenin/TCF4 signaling in sepsis-associated encephalopathy	166
HIF1α-dependent hypoxia response in myeloid cells requires IRE1α	154
Zika virus infection of mature neurons from immunocompetent mice generates a disease-associated microglia and a tauopathy-like phenotype in link with a delayed interferon beta response	153
Correction to: Pharmacologic activation of cholinergic alpha7 nicotinic receptors mitigates depressive-like behavior in a mouse model of chronic stress	153
Carotid artery vascular stenosis causes the blood-CSF barrier damage and neuroinflammation	149
IL-7Rα on CD4+ T cells is required for their survival and the pathogenesis of experimental autoimmune encephalomyelitis	147
The deficient CLEC5A ameliorates the behavioral and pathological deficits via the microglial Aβ clearance in Alzheimer’s disease mouse model	141
Preoperative gut microbiota of POCD patients induces pre- and postoperative cognitive impairment and systemic inflammation in rats	137
Macrophage elastase (MMP12) critically contributes to the development of subretinal fibrosis	128
The associations between plasma soluble Trem1 and neurological diseases: a Mendelian randomization study	126
Maternal immunoglobulin G affects brain development of mouse offspring	125
Integrin Mac1 mediates paraquat and maneb-induced learning and memory impairments in mice through NADPH oxidase–NLRP3 inflammasome axis-dependent microglial activation	123
TPM1 mediates inflammation downstream of TREM2 via the PKA/CREB signaling pathway	120
Flow cytometry identifies changes in peripheral and intrathecal lymphocyte patterns in CNS autoimmune disorders and primary CNS malignancies	119
Brain gray matter astroglia-specific connexin 43 ablation attenuates spinal cord inflammatory demyelination	117
Phosphatidate phosphatase Lipin1 alters mitochondria-associated endoplasmic reticulum membranes (MAMs) homeostasis: effects which contribute to the development of diabetic encephalopathy	102
Citrobacter rodentium infection impairs dopamine metabolism and exacerbates the pathology of Parkinson’s disease in mice	100
Therapeutic intervention in neuroinflammation for neovascular ocular diseases through targeting the cGAS-STING-necroptosis pathway	91

Inhibition of histone deacetylase 6 alleviates neuropathic pain via direct regulating post-translation of spinal STAT3 and decreasing downstream C-C Motif Chemokine Ligand 7 synthesis	90
Microglia-derived exosomes modulate myelin regeneration via miR-615-5p/MYRF axis	89
How the gut microbiota impacts neurodegenerative diseases by modulating CNS immune cells	87
Red nucleus IL-33 facilitates the early development of mononeuropathic pain in male rats by inducing TNF-α through activating ERK, p38 MAPK, and JAK2/STAT3	87
Selective neuronal expression of progranulin is sufficient to provide neuroprotective and anti-inflammatory effects after traumatic brain injury	83
LXR agonism for CNS diseases: promises and challenges	83
Stroke-induced immunosuppression: implications for the prevention and prediction of post-stroke infections	80
Tregs dysfunction aggravates postoperative cognitive impairment in aged mice	80
HMGB1 mediates synaptic loss and cognitive impairment in an animal model of sepsis-associated encephalopathy	79
Exercise suppresses neuroinflammation for alleviating Alzheimer’s disease	78
Marine fungal metabolite butyrolactone I prevents cognitive deficits by relieving inflammation and intestinal microbiota imbalance on aluminum trichloride-injured zebrafish	78
Traumatic brain injury results in unique microglial and astrocyte transcriptomes enriched for type I interferon response	77
Tryptophan-kynurenine metabolism: a link between the gut and brain for depression in inflammatory bowel disease	76
Protein kinase B (AKT) upregulation and Thy-1-αvβ3 integrin-induced phosphorylation of Connexin43 by activated AKT in astrogliosis	75
Exogenous monocyte myeloid-derived suppressor cells ameliorate immune imbalance, neuroinflammation and cognitive impairment in 5xFAD mice infected with Porphyromonas gingivalis	75
α7 Nicotinic acetylcholine receptor: a key receptor in the cholinergic anti-inflammatory pathway exerting an antidepressant effect	74
Injection of amyloid-β to lateral ventricle induces gut microbiota dysbiosis in association with inhibition of cholinergic anti-inflammatory pathways in Alzheimer’s disease	74
Macrophage exosomal miR-30c-2-3p in atherosclerotic plaques aggravates microglial neuroinflammation during large-artery atherosclerotic stroke via TGF-β/SMAD2 pathway	73
Intracranial VCAM1 at time of mechanical thrombectomy predicts ischemic stroke severity	73
Immune response and pathogen invasion at the choroid plexus in the onset of cerebral toxoplasmosis	73
Remibrutinib (LOU064) inhibits neuroinflammation driven by B cells and myeloid cells in preclinical models of multiple sclerosis	72
Innate immune sensors and regulators at the blood brain barrier: focus on toll-like receptors and inflammasomes as mediators of neuro-immune crosstalk and inflammation	72
MicroRNA-155-5p promotes neuroinflammation and central sensitization via inhibiting SIRT1 in a nitroglycerin-induced chronic migraine mouse model	72
AIBP controls TLR4 inflammarafts and mitochondrial dysfunction in a mouse model of Alzheimer’s disease	72
TLR4-dependent neuroinflammation mediates LPS-driven food-reward alterations during high-fat exposure	71
Supporting the differential diagnosis of connective tissue diseases with neurological involvement by blood and cerebrospinal fluid flow cytometry	70
Profiling the neuroimmune cascade in 3xTg-AD mice exposed to successive mild traumatic brain injuries	70
H3K27me3 of Rnf19a promotes neuroinflammatory response during Japanese encephalitis virus infection	70
Sequential treatment with a TNFR2 agonist and a TNFR1 antagonist improves outcomes in a humanized mouse model for MS	69
Immunotherapy with an antibody against CD1d modulates neuroinflammation in an α-synuclein transgenic model of Lewy body like disease	69
Single-cell RNA sequencing reveals peripheral blood leukocyte responses to spinal cord injury in mice with humanised immune systems	69
Deterioration of neuroimmune homeostasis in Alzheimer’s Disease patients who survive a COVID-19 infection	68
Chronic rapid eye movement sleep deprivation aggravates the pathogenesis of Alzheimer’s disease by decreasing brain O-GlcNAc cycling in mice	68
NLRX1 limits inflammatory neurodegeneration in the anterior visual pathway	67
IDO1 modulates pain sensitivity and comorbid anxiety in chronic migraine through microglial activation and synaptic pruning	66
Correction: Hydrogen sulfide-releasing cyclooxygenase inhibitor ATB-346 enhances motor function and reduces cortical lesion volume following traumatic brain injury in mice	66
Inflammasomes at the crossroads of traumatic brain injury and post-traumatic epilepsy	66
Decoding Behcet’s Uveitis: an In-depth review of pathogenesis and therapeutic advances	65
miR-19a/b-3p promotes inflammation during cerebral ischemia/reperfusion injury via SIRT1/FoxO3/SPHK1 pathway	64
Compromised endothelial Wnt/β-catenin signaling mediates the blood-brain barrier disruption and leads to neuroinflammation in endotoxemia	64