BMC Medicine

Article	Citations
Neutrophil to lymphocyte ratio and cancer prognosis: an umbrella review of systematic reviews and meta-analyses of observational studies	295
The impact of non-pharmaceutical interventions on SARS-CoV-2 transmission across 130 countries and territories	254
Association between gut microbiota and preeclampsia-eclampsia: a two-sample Mendelian randomization study	230
Mendelian randomization study of inflammatory bowel disease and bone mineral density	201
Effectiveness of COVID-19 vaccines against SARS-CoV-2 variants of concern: a systematic review and meta-analysis	185
Long-term perturbation of the peripheral immune system months after SARS-CoV-2 infection	177
Ketone bodies: from enemy to friend and guardian angel	160
Evaluation of the safety profile of COVID-19 vaccines: a rapid review	160
The triglyceride glucose index is a simple and low-cost marker associated with atherosclerotic cardiovascular disease: a population-based study	156
Causal relationship between gut microbiota and cancers: a two-sample Mendelian randomisation study	145
At what times during infection is SARS-CoV-2 detectable and no longer detectable using RT-PCR-based tests? A systematic review of individual participant data	136
Comparing the effects of HIV self-testing to standard HIV testing for key populations: a systematic review and meta-analysis	119
Consolidated Health Economic Evaluation Reporting Standards 2022 (CHEERS 2022) statement: updated reporting guidance for health economic evaluations	117
Pre-existing health conditions and severe COVID-19 outcomes: an umbrella review approach and meta-analysis of global evidence	115
Perspectives of tumor-infiltrating lymphocyte treatment in solid tumors	114
Sequelae, persistent symptomatology and outcomes after COVID-19 hospitalization: the ANCOHVID multicentre 6-month follow-up study	111
Evidence for treatment with estradiol for women with SARS-CoV-2 infection	110
Causal role of high body mass index in multiple chronic diseases: a systematic review and meta-analysis of Mendelian randomization studies	109
Transmission event of SARS-CoV-2 delta variant reveals multiple vaccine breakthrough infections	108
Estimating the effectiveness of routine asymptomatic PCR testing at different frequencies for the detection of SARS-CoV-2 infections	104
Gut microbiome alterations and gut barrier dysfunction are associated with host immune homeostasis in COVID-19 patients	100
Vegetarian and vegan diets and risks of total and site-specific fractures: results from the prospective EPIC-Oxford study	99
Dietary fruit and vegetable intake, gut microbiota, and type 2 diabetes: results from two large human cohort studies	91
Meat consumption and risk of 25 common conditions: outcome-wide analyses in 475,000 men and women in the UK Biobank study	90
Duration of palliative care before death in international routine practice: a systematic review and meta-analysis	89

Adiposity, metabolites, and colorectal cancer risk: Mendelian randomization study	88
Accurate diagnosis of colorectal cancer based on histopathology images using artificial intelligence	86
Role of circulating polyunsaturated fatty acids on cardiovascular diseases risk: analysis using Mendelian randomization and fatty acid genetic association data from over 114,000 UK Biobank participant	85
Deep learning-based six-type classifier for lung cancer and mimics from histopathological whole slide images: a retrospective study	85
Excess mortality for care home residents during the first 23 weeks of the COVID-19 pandemic in England: a national cohort study	82
Preventable medication harm across health care settings: a systematic review and meta-analysis	82
Evolving phenotypes of non-hospitalized patients that indicate long COVID	81
Association of the American Heart Association’s new “Life’s Essential 8” with all-cause and cardiovascular disease-specific mortality: prospective cohort study	79
Mortality and other adverse outcomes in patients with type 2 diabetes mellitus admitted for COVID-19 in association with glucose-lowering drugs: a nationwide cohort study	78
The global, regional, and national burden of pancreatitis in 195 countries and territories, 1990–2017: a systematic analysis for the Global Burden of Disease Study 2017	78
Studying the post-COVID-19 condition: research challenges, strategies, and importance of Core Outcome Set development	77
COVID-19 pandemic and violence: rising risks and decreasing urgent care-seeking for sexual assault and domestic violence survivors	77
The impact of local and national restrictions in response to COVID-19 on social contacts in England: a longitudinal natural experiment	77
Mapping subnational HIV mortality in six Latin American countries with incomplete vital registration systems	76
Multiple lifestyle factors and depressed mood: a cross-sectional and longitudinal analysis of the UK Biobank (N = 84,860)	75
Risk for newly diagnosed diabetes after COVID-19: a systematic review and meta-analysis	75
Optimizing COVID-19 surveillance in long-term care facilities: a modelling study	74
Circulating inflammatory cytokines and risk of five cancers: a Mendelian randomization analysis	73
Disability, psychological distress and quality of life in relation to cancer diagnosis and cancer type: population-based Australian study of 22,505 cancer survivors and 244,000 people without cancer	73
Relationship between diet quality scores and the risk of frailty and mortality in adults across a wide age spectrum	72
Evaluation and improvement of the National Early Warning Score (NEWS2) for COVID-19: a multi-hospital study	72
Homocysteine, B vitamins, and cardiovascular disease: a Mendelian randomization study	72
HER2 expression, copy number variation and survival outcomes in HER2-low non-metastatic breast cancer: an international multicentre cohort study and TCGA-METABRIC analysis	71
Automated detection of lung nodules and coronary artery calcium using artificial intelligence on low-dose CT scans for lung cancer screening: accuracy and prognostic value	71
Coding long COVID: characterizing a new disease through an ICD-10 lens	70
The gut microbiome: a key player in the complexity of amyotrophic lateral sclerosis (ALS)	69
Distinct clinical and somatic mutational features of breast tumors with high-, low-, or non-expressing human epidermal growth factor receptor 2 status	68
Biological aging mediates the associations between urinary metals and osteoarthritis among U.S. adults	68
There is no such thing as a validated prediction model	67
Ketone body β-hydroxybutyrate ameliorates colitis by promoting M2 macrophage polarization through the STAT6-dependent signaling pathway	67
Obese visceral fat tissue inflammation: from protective to detrimental?	65
Impact of Covid-19 in pregnancy on mother’s psychological status and infant’s neurobehavioral development: a longitudinal cohort study in China	65
Body mass index and waist circumference in relation to the risk of 26 types of cancer: a prospective cohort study of 3.5 million adults in Spain	64
rs1990622 variant associates with Alzheimer’s disease and regulates TMEM106B expression in human brain tissues	64
Systematic review and meta-analysis of the diagnostic accuracy of prostate-specific antigen (PSA) for the detection of prostate cancer in symptomatic patients	64
Risk/benefit tradeoff of habitual physical activity and air pollution on chronic pulmonary obstructive disease: findings from a large prospective cohort study	62
Effects of personalized diets by prediction of glycemic responses on glycemic control and metabolic health in newly diagnosed T2DM: a randomized dietary intervention pilot trial	61
Medical cannabinoids: a pharmacology-based systematic review and meta-analysis for all relevant medical indications	61
The prevalence of onchocerciasis in Africa and Yemen, 2000–2018: a geospatial analysis	61
Human serum from SARS-CoV-2-vaccinated and COVID-19 patients shows reduced binding to the RBD of SARS-CoV-2 Omicron variant	61
Oxidative stress gene expression, DNA methylation, and gut microbiota interaction trigger Crohn’s disease: a multi-omics Mendelian randomization study	60
Clinical outcomes in patients with atrial fibrillation and frailty: insights from the ENGAGE AF-TIMI 48 trial	60
Relationship of body mass index with frailty and all-cause mortality among middle-aged and older adults	60
Targeted therapies for cancer	60
The COVID-19 pandemic in the African continent	59
Gestational diabetes mellitus is associated with the neonatal gut microbiota and metabolome	59
Sex differences in the association between major cardiovascular risk factors in midlife and dementia: a cohort study using data from the UK Biobank	59
Revisiting the seven pillars of RDoC	58
Risk of cancer in regular and low meat-eaters, fish-eaters, and vegetarians: a prospective analysis of UK Biobank participants	58
Comparison of two different frailty measurements and risk of hospitalisation or death from COVID-19: findings from UK Biobank	58

Associations between dietary patterns and the incidence of total and fatal cardiovascular disease and all-cause mortality in 116,806 individuals from the UK Biobank: a prospective cohort study	57
Impact of COVID-19 lockdown on the incidence and mortality of acute exacerbations of chronic obstructive pulmonary disease: national interrupted time series analyses for Scotland and Wales	57
Effectiveness of inactivated and Ad5-nCoV COVID-19 vaccines against SARS-CoV-2 Omicron BA. 2 variant infection, severe illness, and death	57
One-year follow-up of chest CT findings in patients after SARS-CoV-2 infection	56
Pattern and trend of five major musculoskeletal disorders in China from 1990 to 2017: findings from the Global Burden of Disease Study 2017	56
The accuracy of pulse oximetry in measuring oxygen saturation by levels of skin pigmentation: a systematic review and meta-analysis	55
Dietary fibre in hypertension and cardiovascular disease management: systematic review and meta-analyses	55
Who should be prioritized for COVID-19 vaccination in China? A descriptive study	53
5mC regulator-mediated molecular subtypes depict the hallmarks of the tumor microenvironment and guide precision medicine in bladder cancer	53
Humoral immune responses during SARS-CoV-2 mRNA vaccine administration in seropositive and seronegative individuals	53
Association between patterns of alcohol consumption (beverage type, frequency and consumption with food) and risk of adverse health outcomes: a prospective cohort study	53
Sleep disturbances and the speed of multimorbidity development in old age: results from a longitudinal population-based study	52
Case study research for better evaluations of complex interventions: rationale and challenges	52
Humoral immune response after different SARS-CoV-2 vaccination regimens	51
Comparative kinetics of SARS-CoV-2 anti-spike protein RBD IgGs and neutralizing antibodies in convalescent and naïve recipients of the BNT162b2 mRNA vaccine versus COVID-19 patients	51
Modelling upper respiratory viral load dynamics of SARS-CoV-2	51
Predictive value of circulating NMR metabolic biomarkers for type 2 diabetes risk in the UK Biobank study	50
Prevalence and risk factors of post-COVID-19 condition in adults and children at 6 and 12 months after hospital discharge: a prospective, cohort study in Moscow (StopCOVID)	50
C-reactive protein and cancer risk: a pan-cancer study of prospective cohort and Mendelian randomization analysis	50
Development and validation of an artificial intelligence system for grading colposcopic impressions and guiding biopsies	50
Association between thyroid dysfunction and type 2 diabetes: a meta-analysis of prospective observational studies	49
Cardiovascular implications of COVID-19 versus influenza infection: a review	48
Development and validation of a lifestyle-based model for colorectal cancer risk prediction: the LiFeCRC score	48
The impact of race and ethnicity in breast cancer—disparities and implications for precision oncology	48
Costs of multimorbidity: a systematic review and meta-analyses	48
Breast cancer risk factors and their effects on survival: a Mendelian randomisation study	48
SOCRATES-CoMix: a platform for timely and open-source contact mixing data during and in between COVID-19 surges and interventions in over 20 European countries	47
Circulating vitamin C concentration and risk of cancers: a Mendelian randomization study	47
Mediterranean diet adherence is associated with lower dementia risk, independent of genetic predisposition: findings from the UK Biobank prospective cohort study	47
Updated adolescent diagnostic criteria for polycystic ovary syndrome: impact on prevalence and longitudinal body mass index trajectories from birth to adulthood	47
SARS-CoV-2 exposure in Malawian blood donors: an analysis of seroprevalence and variant dynamics between January 2020 and July 2021	46
Exploring health in the UK Biobank: associations with sociodemographic characteristics, psychosocial factors, lifestyle and environmental exposures	46
Insulin resistance, diabetic kidney disease, and all-cause mortality in individuals with type 2 diabetes: a prospective cohort study	46
Associations between grip strength, brain structure, and mental health in > 40,000 participants from the UK Biobank	46
Bacterial vaginosis: drivers of recurrence and challenges and opportunities in partner treatment	46
Ambient air pollution associated with incidence and dynamic progression of type 2 diabetes: a trajectory analysis of a population-based cohort	46
Development of the reproduction number from coronavirus SARS-CoV-2 case data in Germany and implications for political measures	46
ROB-MEN: a tool to assess risk of bias due to missing evidence in network meta-analysis	45
Research priorities for Long Covid: refined through an international multi-stakeholder forum	45
Adding flexibility to clinical trial designs: an example-based guide to the practical use of adaptive designs	45
Impact of replacing sedentary behaviour with other movement behaviours on depression and anxiety symptoms: a prospective cohort study in the UK Biobank	44
Evaluating the next generation of RSV intervention strategies: a mathematical modelling study and cost-effectiveness analysis	44
Contribution of cystatin C- and creatinine-based definitions of chronic kidney disease to cardiovascular risk assessment in 20 population-based and 3 disease cohorts: the BiomarCaRE project	43
Single-cell analysis of menstrual endometrial tissues defines phenotypes associated with endometriosis	43
New strategies to improve clinical outcomes for diabetic kidney disease	41
Global, regional, and national burden of cardiovascular diseases in youths and young adults aged 15–39 years in 204 countries/territories, 1990–2019: a systematic analysis of Global Burden of Disease	41
Reducing travel-related SARS-CoV-2 transmission with layered mitigation measures: symptom monitoring, quarantine, and testing	41
Following the science? Comparison of methodological and reporting quality of covid-19 and other research from the first wave of the pandemic	41
Changes in evidence for studies assessing interventions for COVID-19 reported in preprints: meta-research study	41
Frailty in individuals with depression, bipolar disorder and anxiety disorders: longitudinal analyses of all-cause mortality	41
When a pandemic and an epidemic collide: COVID-19, gut microbiota, and the double burden of malnutrition	40
Multiplex immunohistochemistry defines the tumor immune microenvironment and immunotherapeutic outcome in CLDN18.2-positive gastric cancer	40
Machine learning for subtype definition and risk prediction in heart failure, acute coronary syndromes and atrial fibrillation: systematic review of validity and clinical utility	39
The dynamic wound microbiome	39
Clinical translation of stem cell therapy for spinal cord injury still premature: results from a single-arm meta-analysis based on 62 clinical trials	39
Cisplatin and carboplatin result in similar gonadotoxicity in immature human testis with implications for fertility preservation in childhood cancer	39
Mutations of PI3K-AKT-mTOR pathway as predictors for immune cell infiltration and immunotherapy efficacy in dMMR/MSI-H gastric adenocarcinoma	39
Tuberculosis related disability: a systematic review and meta-analysis	39
Relation of severe COVID-19 to polypharmacy and prescribing of psychotropic drugs: the REACT-SCOT case-control study	39
Ezetimibe combination therapy with statin for non-alcoholic fatty liver disease: an open-label randomized controlled trial (ESSENTIAL study)	39
A single-oral bolus of 100,000 IU of cholecalciferol at hospital admission did not improve outcomes in the COVID-19 disease: the COVID-VIT-D—a randomised multicentre international clinical trial	38
Long COVID 12 months after discharge: persistent symptoms in patients hospitalised due to COVID-19 and patients hospitalised due to other causes—a multicentre cohort study	38
Understanding the role of the paramedic in primary care: a realist review	38
Asthma and the risk of gastrointestinal disorders: a Mendelian randomization study	37
Systematic analysis of IL-6 as a predictive biomarker and desensitizer of immunotherapy responses in patients with non-small cell lung cancer	37
Sex differences in systemic metabolites at four life stages: cohort study with repeated metabolomics	37
Cooking oil/fat consumption and deaths from cardiometabolic diseases and other causes: prospective analysis of 521,120 individuals	37
Quantifying the potential value of antigen-detection rapid diagnostic tests for COVID-19: a modelling analysis	37
Individual and combined associations between cardiorespiratory fitness and grip strength with common mental disorders: a prospective cohort study in the UK Biobank	37
Association of alcohol consumption with morbidity and mortality in patients with cardiovascular disease: original data and meta-analysis of 48,423 men and women	37
Cross-talks between gut microbiota and tobacco smoking: a two-sample Mendelian randomization study	37
Identification of NOTCH4 mutation as a response biomarker for immune checkpoint inhibitor therapy	36
High intake of vegetables is linked to lower white blood cell profile and the effect is mediated by the gut microbiome	36
Breastfeeding and the risk of childhood cancer: a systematic review and dose-response meta-analysis	36
Short-chain fatty acid concentrations in the incidence and risk-stratification of colorectal cancer: a systematic review and meta-analysis	36
Maternal dietary quality, inflammatory potential and childhood adiposity: an individual participant data pooled analysis of seven European cohorts in the ALPHABET consortium	36
Ethnic differences in cardiovascular risk: examining differential exposure and susceptibility to risk factors	35
Persistence and baseline determinants of seropositivity and reinfection rates in health care workers up to 12.5 months after COVID-19	35
Effects of maternal folic acid supplementation during the second and third trimesters of pregnancy on neurocognitive development in the child: an 11-year follow-up from a randomised controlled trial	35
The role of cortisol in ischemic heart disease, ischemic stroke, type 2 diabetes, and cardiovascular disease risk factors: a bi-directional Mendelian randomization study	35

Individual social contact data and population mobility data as early markers of SARS-CoV-2 transmission dynamics during the first wave in Germany—an analysis based on the COVIMOD study	35
Association between cardiometabolic disease multimorbidity and all-cause mortality in 2 million women and men registered in UK general practices	35
Is transcranial direct current stimulation, alone or in combination with antidepressant medications or psychotherapies, effective in treating major depressive disorder? A systematic review and meta-an	35
Circulating levels of micronutrients and risk of infections: a Mendelian randomization study	35
Prolonged anesthesia induces neuroinflammation and complement-mediated microglial synaptic elimination involved in neurocognitive dysfunction and anxiety-like behaviors	34
Associations of handgrip strength with morbidity and all-cause mortality of cardiometabolic multimorbidity	34
The need for screening, early diagnosis, and prediction of chronic kidney disease in people with diabetes in low- and middle-income countries—a review of the current literature	34
L-shaped association of serum 25-hydroxyvitamin D concentrations with cardiovascular and all-cause mortality in individuals with osteoarthritis: results from the NHANES database prospective cohort stu	34
Reproductive issues in carriers of germline pathogenic variants in the BRCA1/2 genes: an expert meeting	34
HBeAg mediates inflammatory functions of macrophages by TLR2 contributing to hepatic fibrosis	33
Silent cerebral infarcts in patients with sickle cell disease: a systematic review and meta-analysis	33
Genome-wide analysis of blood lipid metabolites in over 5000 South Asians reveals biological insights at cardiometabolic disease loci	33
Identifying molecular mediators of the relationship between body mass index and endometrial cancer risk: a Mendelian randomization analysis	33
Understanding the impact of exposure to adverse socioeconomic conditions on chronic stress from a complexity science perspective	33
Association of meat, vegetarian, pescatarian and fish-poultry diets with risk of 19 cancer sites and all cancer: findings from the UK Biobank prospective cohort study and meta-analysis	33
Chromosomally normal miscarriage is associated with vaginal dysbiosis and local inflammation	32
Vaccination strategies for measles control and elimination: time to strengthen local initiatives	32
Models of COVID-19 vaccine prioritisation: a systematic literature search and narrative review	32
What are the inpatient and day case costs following primary total hip replacement of patients treated for prosthetic joint infection: a matched cohort study using linked data from the National Joint R	32
Determinants of pre-vaccination antibody responses to SARS-CoV-2: a population-based longitudinal study (COVIDENCE UK)	32
Metagenome-wide association study of gut microbiome revealed potential microbial marker set for diagnosis of pediatric myasthenia gravis	31
Serum neurofilament light and tau as prognostic markers for all-cause mortality in the elderly general population—an analysis from the MEMO study	31
Associations between types and sources of dietary carbohydrates and cardiovascular disease risk: a prospective cohort study of UK Biobank participants	31
Non-genetic risk and protective factors and biomarkers for neurological disorders: a meta-umbrella systematic review of umbrella reviews	31
SGLT-2 inhibitors and in-stent restenosis-related events after acute myocardial infarction: an observational study in patients with type 2 diabetes	31
Risk factors for human papillomavirus infection, cervical intraepithelial neoplasia and cervical cancer: an umbrella review and follow-up Mendelian randomisation studies	31
Efficacy and safety of pyrotinib in advanced lung adenocarcinoma with HER2 mutations: a multicenter, single-arm, phase II trial	31
Association between HIV infection and hypertension: a global systematic review and meta-analysis of cross-sectional studies	31
Genome-wide genetic links between amyotrophic lateral sclerosis and autoimmune diseases	31
Systematic review of Mendelian randomization studies on risk of cancer	30
Real-world effectiveness of primary screening with high-risk human papillomavirus testing in the cervical cancer screening programme in China: a nationwide, population-based study	30
Ending malnutrition in all its forms requires scaling up proven nutrition interventions and much more: a 129-country analysis	30
Associations of the circulating levels of cytokines with risk of amyotrophic lateral sclerosis: a Mendelian randomization study	30
Plasma metabolomic profiles of dementia: a prospective study of 110,655 participants in the UK Biobank	30
Association between circulating vitamin E and ten common cancers: evidence from large-scale Mendelian randomization analysis and a longitudinal cohort study	30
Using person-specific networks in psychotherapy: challenges, limitations, and how we could use them anyway	29
Multimodal non-invasive non-pharmacological therapies for chronic pain: mechanisms and progress	29
Global diversity of policy, coverage, and demand of COVID-19 vaccines: a descriptive study	29
In utero Zika virus exposure and neurodevelopment at 24 months in toddlers normocephalic at birth: a cohort study	29
Metabolic signatures of greater body size and their associations with risk of colorectal and endometrial cancers in the European Prospective Investigation into Cancer and Nutrition	29
The effects of dietary and lifestyle interventions among pregnant women with overweight or obesity on early childhood outcomes: an individual participant data meta-analysis from randomised trials	29
Reducing youth suicide: systems modelling and simulation to guide targeted investments across the determinants	29
Ultra-processed food and incident type 2 diabetes: studying the underlying consumption patterns to unravel the health effects of this heterogeneous food category in the prospective Lifelines cohort	29
Exit strategies: optimising feasible surveillance for detection, elimination, and ongoing prevention of COVID-19 community transmission	29
Clinical complexity and impact of the ABC (Atrial fibrillation Better Care) pathway in patients with atrial fibrillation: a report from the ESC-EHRA EURObservational Research Programme in AF General L	29
Physical activity enhances the improvement of body mass index and metabolism by inulin: a multicenter randomized placebo-controlled trial performed in obese individuals	28
Functional connectivity changes in cerebral small vessel disease - a systematic review of the resting-state MRI literature	28
Cell-free DNA methylation markers for differential diagnosis of hepatocellular carcinoma	28
Associations between an inflammatory diet index and severe non-alcoholic fatty liver disease: a prospective study of 171,544 UK Biobank participants	28
Long-term impact of a conditional cash transfer programme on maternal mortality: a nationwide analysis of Brazilian longitudinal data	28
The potential impact of Anopheles stephensi establishment on the transmission of Plasmodium falciparum in Ethiopia and prospective control measures	28
Genomic correlation, shared loci, and causal relationship between obesity and polycystic ovary syndrome: a large-scale genome-wide cross-trait analysis	28
Understanding personalized dynamics to inform precision medicine: a dynamic time warp analysis of 255 depressed inpatients	28
m6A regulator expression profile predicts the prognosis, benefit of adjuvant chemotherapy, and response to anti-PD-1 immunotherapy in patients with small-cell lung cancer	28
Patient factors influencing acute gluten reactions and cytokine release in treated coeliac disease	28
Gut microbiota signatures of long-term and short-term plant-based dietary pattern and cardiometabolic health: a prospective cohort study	28
Durations of asymptomatic, symptomatic, and care-seeking phases of tuberculosis disease with a Bayesian analysis of prevalence survey and notification data	27
Deep learning radiomics based on contrast-enhanced ultrasound images for assisted diagnosis of pancreatic ductal adenocarcinoma and chronic pancreatitis	27
Computer-assisted quantification of tumor-associated collagen signatures to improve the prognosis prediction of breast cancer	27
The association between mechanical ventilator compatible bed occupancy and mortality risk in intensive care patients with COVID-19: a national retrospective cohort study	27
EPHA7 mutation as a predictive biomarker for immune checkpoint inhibitors in multiple cancers	27
Comparison of submucosal and subserosal approaches toward optimized indocyanine green tracer-guided laparoscopic lymphadenectomy for patients with gastric cancer (FUGES-019): a randomized controlled t	27
A healthy lifestyle is positively associated with mental health and well-being and core markers in ageing	27
Age and product dependent vaccine effectiveness against SARS-CoV-2 infection and hospitalisation among adults in Norway: a national cohort study, July–November 2021	27
Maternal factors during pregnancy influencing maternal, fetal, and childhood outcomes	27
The epidemiologic impact and cost-effectiveness of new tuberculosis vaccines on multidrug-resistant tuberculosis in India and China	27
Risk of bias in observational studies using routinely collected data of comparative effectiveness research: a meta-research study	26
The effect of high-polyphenol Mediterranean diet on visceral adiposity: the DIRECT PLUS randomized controlled trial	26
The dose-response relationship between socioeconomic deprivation and alcohol-attributable mortality risk—a systematic review and meta-analysis	26
SARS-CoV-2 infection, vaccination, and antibody response trajectories in adults: a cohort study in Catalonia	26
Dietary intake of trans fatty acids and breast cancer risk in 9 European countries	26
A phenome-wide association study of ABO blood groups	26
Association of statin use in older people primary prevention group with risk of cardiovascular events and mortality: a systematic review and meta-analysis of observational studies	26
Associations of genetically predicted IL-6 signaling with cardiovascular disease risk across population subgroups	26
Variability of multi-omics profiles in a population-based child cohort	26
Do nuclear magnetic resonance (NMR)-based metabolomics improve the prediction of pregnancy-related disorders? Findings from a UK birth cohort with independent validation	25
Glycolysis-associated lncRNAs identify a subgroup of cancer patients with poor prognoses and a high-infiltration immune microenvironment	25
Effects of ketogenic diet on health outcomes: an umbrella review of meta-analyses of randomized clinical trials	25
Patient and health provider costs of integrated HIV, diabetes and hypertension ambulatory health services in low-income settings — an empirical socio-economic cohort study in Tanzania and Uganda	25
Incidence of immune-mediated inflammatory diseases following COVID-19: a matched cohort study in UK primary care	25
Neoadjuvant pyrotinib, trastuzumab, and docetaxel for HER2-positive breast cancer (PHEDRA): a double-blind, randomized phase 3 trial	25
Psoriasis and cardiovascular disease risk in European and East Asian populations: evidence from meta-analysis and Mendelian randomization analysis	25
Shaping a data-driven era in dementia care pathway through computational neurology approaches	25
Impact of clinical phenotypes on management and outcomes in European atrial fibrillation patients: a report from the ESC-EHRA EURObservational Research Programme in AF (EORP-AF) General Long-Term Regi	25
Effectiveness and cost-effectiveness of eliminating cervical cancer through a tailored optimal pathway: a modeling study	25
Identification of novel proteins for lacunar stroke by integrating genome-wide association data and human brain proteomes	25
Retinal age gap as a predictive biomarker of stroke risk	25
Sleep in disorders of consciousness: behavioral and polysomnographic recording	24
Relation of severe COVID-19 in Scotland to transmission-related factors and risk conditions eligible for shielding support: REACT-SCOT case-control study	24
Methylmalonic acid, vitamin B12, renal function, and risk of all-cause mortality in the general population: results from the prospective Lifelines-MINUTHE study	24
Alcohol drinking and risks of liver cancer and non-neoplastic chronic liver diseases in China: a 10-year prospective study of 0.5 million adults	24
Evaluation of glycemic traits in susceptibility to COVID-19 risk: a Mendelian randomization study	24
A comprehensive gene-centric pleiotropic association analysis for 14 psychiatric disorders with GWAS summary statistics	24
Different hypertension thresholds and cognitive decline: a pooled analysis of three ageing cohorts	24
Psychopathological symptom network structure in transgender and gender queer youth reporting parental psychological abuse: a network analysis	24