BMC Biology

Article	Citations
An intelligent workflow for sub-nanoscale 3D reconstruction of intact synapses from serial section electron tomography	134
CD4+ and CD8+ regulatory T cell characterization in the rat using a unique transgenic Foxp3-EGFP model	124
Histone modifications and DNA methylation act cooperatively in regulating symbiosis genes in the sea anemone Aiptasia	109
YHSeqY3000 panel captures all founding lineages in the Chinese paternal genomic diversity database	87
The genome of the pygmy right whale illuminates the evolution of rorquals	82
Skin-penetrating nematodes exhibit life-stage-specific interactions with host-associated and environmental bacteria	78
Attention to visual motion suppresses neuronal and behavioral sensitivity in nearby feature space	64
The HSP40 family chaperone isoform DNAJB6b prevents neuronal cells from tau aggregation	57
Multidimensional associations between nutrient intake and healthy ageing in humans	57
Global analysis of neuropeptide receptor conservation across phylum Nematoda	56
Long-term live imaging and multiscale analysis identify heterogeneity and core principles of epithelial organoid morphogenesis	53
Modality-specific sensory and decisional carryover effects in duration perception	52
Functional analysis of the mating type genes in Verticillium dahliae	51
Expression profiles of the autism-related SHANK proteins in the human brain	49
The dorsoanterior brain of adult amphioxus shares similarities in expression profile and neuronal composition with the vertebrate telencephalon	48
Hearing loss genes reveal patterns of adaptive evolution at the coding and non-coding levels in mammals	48
Imputation strategies for genomic prediction using nanopore sequencing	48
Age-related susceptibility to insulin resistance arises from a combination of CPT1B decline and lipid overload	46
Nuclear receptor RXRα binds the precursor of miR-103 to inhibit its maturation	44
Phylotranscriptomics points to multiple independent origins of multicellularity and cellular differentiation in the volvocine algae	43
Leveraging the predictive power of 3D organoids in dogs to develop new treatments for man and man’s best friend	43
A network of transcription factors in complex with a regulating cell cycle cyclin orchestrates fungal oxidative stress responses	43
Modality-specific effects of threat on self-motion perception	42
Epigenetic regulation of human-specific gene expression in the prefrontal cortex	42
Spatio-temporal characterization of phenotypic resistance in malaria vector species	40

Transcriptomic underpinnings of high and low mirror aggression zebrafish behaviours	39
Vimentin-mediated buffering of internal integrin β1 pool increases survival of cells from anoikis	38
Comparative gene retention analysis in barley, wild emmer, and bread wheat pangenome lines reveals factors affecting gene retention following gene duplication	37
Polycomb contraction differentially regulates terminal human hematopoietic differentiation programs	36
A cornucopia of research resources for the fourth rodent malaria parasite species	35
Contrasting outcomes of genome reduction in mikrocytids and microsporidians	35
Gut microbe Lactiplantibacillus plantarum undergoes different evolutionary trajectories between insects and mammals	33
APOBEC3 mutational signatures are associated with extensive and diverse genomic instability across multiple tumour types	33
A brain cyst load-associated antigen is a Toxoplasma gondii biomarker for serodetection of persistent parasites and chronic infection	32
The meaning of ubiquitylation of the DSL ligand Delta for the development of Drosophila	30
Structure modeling hints at a granular organization of the Golgi ribbon	30
Changing turn-over rates regulate abundance of tryptophan, GS biosynthesis, IAA transport and photosynthesis proteins in Arabidopsis growth defense transitions	29
GRK2 regulates GLP-1R-mediated early phase insulin secretion in vivo	29
Apomixis and genetic background affect distinct traits in Hieracium pilosella L. grown under competition	29
Single-cell RNA sequencing integrated with bulk RNA sequencing analysis identifies a tumor immune microenvironment-related lncRNA signature in lung adenocarcinoma	29
Adaptive learning and recall of motor-sensory sequences in adult echolocating bats	29
Independent, but still observant—dog breeds selected for functional independence learn better from a conspecific demonstrator than cooperative breeds in a detour task	28
A muscle exercise research revolution powered by -omics at single cell and nucleus resolution	28
Cdk5-mediated JIP1 phosphorylation regulates axonal outgrowth through Notch1 inhibition	28
Assessing the role of Piscine orthoreovirus in disease and the associated risk for wild Pacific salmon	28
Identification of cell subpopulations associated with disease phenotypes from scRNA-seq data using PACSI	28
A unique effector secreted by Pseudozyma flocculosa mediates its biocontrol activity	28
Reduced intestinal lipid absorption improves glucose metabolism in aged G2-Terc knockout mice	27
Fragmentation in mitochondrial genomes in relation to elevated sequence divergence and extreme rearrangements	27
Muscle miRNAs are influenced by sex at baseline and in response to exercise	27
Differential functions of RhoGDIβ in malignant transformation and progression of urothelial cell following N-butyl-N-(4-hydmoxybutyl) nitrosamine exposure	27
Directional selection coupled with kin selection favors the establishment of senescence	26
Population genomics of an icefish reveals mechanisms of glacier-driven adaptive radiation in Antarctic notothenioids	26
Integration of large and diverse angiosperm DNA fragments into Asian Gnetum mitogenomes	26
The BAF chromatin remodeling complex licenses planarian stem cells access to ectodermal and mesodermal cell fates	26
SMYD3 associates with the NuRD (MTA1/2) complex to regulate transcription and promote proliferation and invasiveness in hepatocellular carcinoma cells	26
Stress decreases spermatozoa quality and induces molecular alterations in zebrafish progeny	25
Dynamics and structural changes of calmodulin upon interaction with the antagonist calmidazolium	25
JNK signaling provides a novel therapeutic target for Rett syndrome	25
TBX3 is dynamically expressed in pancreatic organogenesis and fine-tunes regeneration	25
Reconstruction of gene innovation associated with major evolutionary transitions in the kingdom Fungi	25
Assessment of assumptions underlying models of prokaryotic pangenome evolution	24
A gene deriving from the ancestral sex chromosomes was lost from the X and retained on the Y chromosome in eutherian mammals	24
Assessing optimal: inequalities in codon optimization algorithms	24
Stage-specific expression of an odorant receptor underlies olfactory behavioral plasticity in Spodoptera littoralis larvae	24
Deviations from temporal scaling support a stage-specific regulation for C. elegans postembryonic development	24
Recognition of nonself is necessary to activate Drosophila’s immune response against an insect parasite	24
Enhanced transcriptome-wide RNA G-quadruplex sequencing for low RNA input samples with rG4-seq 2.0	24
Chronic high-sugar diet in adulthood protects Caenorhabditis elegans from 6-OHDA-induced dopaminergic neurodegeneration	24
Evolutionary conserved relocation of chromatin remodeling complexes to the mitotic apparatus	24
Regulatory and evolutionary impact of DNA methylation in two songbird species and their naturally occurring F1 hybrids	24
Predicting intercellular communication based on metabolite-related ligand-receptor interactions with MRCLinkdb	24
Time of day as a critical variable in biology	24
OLIG2 regulates lncRNAs and its own expression during oligodendrocyte lineage formation	24
Establishment and characterization of canine mammary tumoroids for translational research	23

Non-human peptides revealed in blood reflect the composition of intestinal microbiota	23
Casein kinase 1α mediates estradiol secretion via CYP19A1 expression in mouse ovarian granulosa cells	23
Single-cell RNA sequencing of the retina in a model of retinitis pigmentosa reveals early responses to degeneration in rods and cones	23
Ancestral reconstruction reveals catalytic inactivation of activation-induced cytidine deaminase concomitant with cold water adaption in the Gadiformes bony fish	23
Integrative single-cell RNA-seq and ATAC-seq analysis of myogenic differentiation in pig	23
The stem rust fungus Puccinia graminis f. sp. tritici induces centromeric small RNAs during late infection that are associated with genome-wide DNA methylation	23
Optimization of the antimicrobial peptide Bac7 by deep mutational scanning	23
Anaerobic derivates of mitochondria and peroxisomes in the free-living amoeba Pelomyxa schiedti revealed by single-cell genomics	23
The influence of immune challenges on the mean and variance in reproductive investment: a meta-analysis of the terminal investment hypothesis	23
Neuromolecular responses in disrupted mutualistic cleaning interactions under future environmental conditions	22
Author Correction: Novel function of single-target regulator NorR involved in swarming motility and biofilm formation revealed in Vibrio alginolyticus	22
Comparative whole-genome transcriptome analysis in renal cell populations reveals high tissue specificity of MAPK/ERK targets in embryonic kidney	22
A new lineage of non-photosynthetic green algae with extreme organellar genomes	22
Chronic sleep deprivation disturbs energy balance modulated by suprachiasmatic nucleus efferents in mice	22
Insights into the structure-function relationship of the NorQ/NorD chaperones from Paracoccus denitrificans reveal shared principles of interacting MoxR AAA+/VWA domain proteins	22
Microbial diversity and ecological complexity emerging from environmental variation and horizontal gene transfer in a simple mathematical model	22
Natural abundance isotope ratios to differentiate sources of carbon used during tumor growth in vivo	21
Functional characterization of the second feedback loop in the circadian clock of the Antarctic krill Euphausia superba	21
Regulatory changes associated with the head to trunk developmental transition	21
High-resolution structure of the amino acid transporter AdiC reveals insights into the role of water molecules and networks in oligomerization and substrate binding	21
Spatial biology of Ising-like synthetic genetic networks	21
The cytoskeleton adaptor protein Sorbs1 controls the development of lymphatic and venous vessels in zebrafish	21
Fruit bats adjust their foraging strategies to urban environments to diversify their diet	21
α2β1 integrins spatially restrict Cdc42 activity to stabilise adherens junctions	21
Personalised modelling of clinical heterogeneity between medium-chain acyl-CoA dehydrogenase patients	21
A mucus layer derived from porcine intestinal organoid air–liquid interface monolayer attenuates swine enteric coronavirus infection by antiviral activity of Muc2	21
Conservation and trans-regulation of histone modification in the A and B subgenomes of polyploid wheat during domestication and ploidy transition	21
Uncovering the history of recombination and population structure in western Canadian stripe rust populations through mating type alleles	21
Large-scale data analysis for robotic yeast one-hybrid platforms and multi-disciplinary studies using GateMultiplex	20
The fly liquid-food electroshock assay (FLEA) suggests opposite roles for neuropeptide F in avoidance of bitterness and shock	20
Experimental infection with the hookworm, Necator americanus, is associated with stable gut microbial diversity in human volunteers with relapsing multiple sclerosis	20
Two zinc finger proteins, VdZFP1 and VdZFP2, interact with VdCmr1 to promote melanized microsclerotia development and stress tolerance in Verticillium dahliae	20
Notch signaling is a critical initiator of roof plate formation as revealed by the use of RNA profiling of the dorsal neural tube	20
Early inhibition of BRD4 facilitates iPSC reprogramming via accelerating rDNA dynamic expression	20
Co-option of the limb patterning program in cephalopod eye development	20
Global phylogenomic assessment of Leptoseris and Agaricia reveals substantial undescribed diversity at mesophotic depths	20
Receptor deorphanization in an echinoderm reveals kisspeptin evolution and relationship with SALMFamide neuropeptides	20
Dissection of a sensorimotor circuit underlying pathogen aversion in C. elegans	20
Investigating the characteristics of genes and variants associated with self-reported hearing difficulty in older adults in the UK Biobank	20
Distribution and diversity of ROS-generating enzymes across the animal kingdom, with a focus on sponges (Porifera)	20
Olfactory sensitivity differentiates morphologically distinct worker castes in Camponotus floridanus	19
Stomatal conductance limited the CO2 response of grassland in the last century	19
Taxonomy-aware, sequence similarity ranking reliably predicts phage–host relationships	19
Identification of herbal teas and their compounds eliciting antiviral activity against SARS-CoV-2 in vitro	19
Dopamine D1- and D2-like receptors oppositely regulate lifespan via a dietary restriction mechanism in Caenorhabditis elegans	19
Differentiated adaptative genetic architecture and language-related demographical history in South China inferred from 619 genomes from 56 populations	19
Irisin mediates beiging of adipose-derived mesenchymal stem cells through binding to TRPC3	19
Flexible and stretchable polymer optical fibers for chronic brain and vagus nerve optogenetic stimulations in free-behaving animals	19
Parental energy-sensing pathways control intergenerational offspring sex determination in the nematode Auanema freiburgensis	19
Competition-based screening helps to secure the evolutionary stability of a defensive microbiome	19
Cyclic stretch enhances neutrophil extracellular trap formation	19
Ileum tissue single-cell mRNA sequencing elucidates the cellular architecture of pathophysiological changes associated with weaning in piglets	19
The Sapria himalayana genome provides new insights into the lifestyle of endoparasitic plants	19
Asynchronous embryonic germ cell development leads to a heterogeneity of postnatal ovarian follicle activation and may influence the timing of puberty onset in mice	19
Diversely evolved xibalbin variants from remipede venom inhibit potassium channels and activate PKA-II and Erk1/2 signaling	19
Functional characterization of NBS-LRR genes reveals an NBS-LRR gene that mediates resistance against Fusarium wilt	19
Dissecting thrombus-directed chemotaxis and random movement in neutrophil near-thrombus motion in flow chambers	18
Hibernation reduces GABA signaling in the brainstem to enhance motor activity of breathing at cool temperatures	18
Asymmetric and parallel subgenome selection co-shape common carp domestication	18
Isolation and characterisation of novel Methanocorpusculum species indicates the genus is ancestrally host-associated	18
Integrative single-cell RNA-seq analysis of vascularized cerebral organoids	18
Associations between DNA methylation and gene regulation depend on chromatin accessibility during transgenerational plasticity	18
Reconstructing the ancestral gene pool to uncover the origins and genetic links of Hmong–Mien speakers	18
A high-performance computational workflow to accelerate GATK SNP detection across a 25-genome dataset	18
Back to the roots, desiccation and radiation resistances are ancestral characters in bdelloid rotifers	18
The subcellular distribution of miRNA isoforms, tRNA-derived fragments, and rRNA-derived fragments depends on nucleotide sequence and cell type	18
Mycobacterium leprae diversity and population dynamics in medieval Europe from novel ancient genomes	18
Uncovering bacterial-mammalian cell interactions via single-cell tracking	18
Guanine crystal formation by bacteria	18
Pangenome analysis reveals transposon-driven genome evolution in cotton	18
Molecular mechanisms underlying the neural correlates of working memory	18
Fossil-calibrated molecular clock data enable reconstruction of steps leading to differentiated multicellularity and anisogamy in the Volvocine algae	18
Deficient DNA base-excision repair in the forebrain leads to a sex-specific anxiety-like phenotype in mice	17
Evolution of loss of heterozygosity patterns in hybrid genomes of Candida yeast pathogens	17
Human thirst behavior requires transformation of sensory inputs by intrinsic brain networks	17
An alternating active-dormitive strategy enables disadvantaged prey to outcompete the perennially active prey through Parrondo’s paradox	17
A hyperspectral open-source imager (HOSI)	17
Comparative 3D genome architecture in vertebrates	17
Snakes on a plain: biotic and abiotic factors determine venom compositional variation in a wide-ranging generalist rattlesnake	17
Experimental demonstration of tethered gene drive systems for confined population modification or suppression	17

The visual pathway in sea spiders (Pycnogonida) displays a simple serial layout with similarities to the median eye pathway in horseshoe crabs	17
PharmRL: pharmacophore elucidation with deep geometric reinforcement learning	17
mtIF3 is locally translated in axons and regulates mitochondrial translation for axonal growth	17
Cuticular competing endogenous RNAs regulate insecticide penetration and resistance in a major agricultural pest	17
Genome-wide screening reveals the genetic basis of mammalian embryonic eye development	17
A unique self-truncation of bacterial GH5 endoglucanases leads to enhanced activity and thermostability	17
The effect of calorie intake, fasting, and dietary composition on metabolic health and gut microbiota in mice	17
Highly flexible metabolism of the marine euglenozoan protist Diplonema papillatum	16
Chronic temperature stress inhibits reproduction and disrupts endocytosis via chaperone titration in Caenorhabditis elegans	16
Life on a leaf: the epiphyte to pathogen continuum and interplay in the phyllosphere	16
Correction to: Resilin matrix distribution, variability and function in Drosophila	16
Transposable element expansion and low-level piRNA silencing in grasshoppers may cause genome gigantism	16
Circadian rhythms in the plant host influence rhythmicity of rhizosphere microbiota	16
A primary cell wall cellulose-dependent defense mechanism against vascular pathogens revealed by time-resolved dual transcriptomics	16
Increased interaction between endoplasmic reticulum and mitochondria following sleep deprivation	16
Loss of splicing factor IK impairs normal skeletal muscle development	16
Author Correction: Unique sperm haplotypes are associated with phenotypically different sperm subpopulations in Astyanax fish	16
The gut symbiont Sphingomonas mediates imidacloprid resistance in the important agricultural insect pest Aphis gossypii Glover	16
The adaptive benefit of evolved increases in hemoglobin-O2 affinity is contingent on tissue O2 diffusing capacity in high-altitude deer mice	16
CmNAC25 targets CmMYB6 to positively regulate anthocyanin biosynthesis during the post-flowering stage in chrysanthemum	16
Author Correction: Diurnal and circadian rhythmicity of the human blood transcriptome overlaps with organ- and tissue-specific expression of a non-human primate	16
Plasma membrane integrity: implications for health and disease	16
Author Correction: Genomic characterization of the world’s longest selection experiment in mouse reveals the complexity of polygenic traits	15
Ancient genomes from the Tang Dynasty capital reveal the genetic legacy of trans-Eurasian communication at the eastern end of Silk Road	15
Comparative genomics of the primary endosymbiont Buchnera aphidicola in aphid hosts and their coevolutionary relationships	15
Eurasian spruce bark beetle detects lanierone using a highly expressed specialist odorant receptor, present in several functional sensillum types	15
Author Correction: Satellitome comparison of two oedipodine grasshoppers highlights the contingent nature of satellite DNA evolution	15
Introgression drives adaptation to the plateau environment in a subterranean rodent	15
Endosomal protein DENND10/FAM45A integrates extracellular vesicle release with cancer cell migration	15
Hidden genomic features of an invasive malaria vector, Anopheles stephensi, revealed by a chromosome-level genome assembly	15
Author Correction: Activation function 1 of progesterone receptor is required for progesterone antagonism of oestrogen action in the uterus	15
The golden genome annotation of Ganoderma lingzhi reveals a more complex scenario of eukaryotic gene structure and transcription activity	15
Wolbachia incompatible insect technique program optimization over large spatial scales using a process-based model of mosquito metapopulation dynamics	15
An economical and highly adaptable optogenetics system for individual and population-level manipulation of Caenorhabditis elegans	15
Construction and characterization of a genome-scale ordered mutant collection of Bacteroides thetaiotaomicron	14
TORC1 regulates the transcriptional response to glucose and developmental cycle via the Tap42-Sit4-Rrd1/2 pathway in Saccharomyces cerevisiae	14
Fast vocal-motor tracking of escaping prey in echolocating bats	14
Telomerase subunit Est2 marks internal sites that are prone to accumulate DNA damage	14
A conformational change of C-reactive protein drives neutrophil extracellular trap formation in inflammation	14
Toxic stress-specific cytoprotective responses regulate learned behavioral decisions in C. elegans	14
Quantifying the proportion of different cell types in the human cortex using DNA methylation profiles	14
Pathogen-derived mechanical cues potentiate the spatio-temporal implementation of plant defense	14
You talkin’ to me? Functional breed selection may have fundamentally influenced dogs’ sensitivity to human verbal communicative cues	14
Evolutionary dynamics of mitochondrial genomes and intracellular transfers among diploid and allopolyploid cotton species	14
Insights into the demographic history of Asia from common ancestry and admixture in the genomic landscape of present-day Austroasiatic speakers	14
Hematopoietic differentiation is characterized by a transient peak of entropy at a single-cell level	14
GATA3 functions downstream of BRCA1 to promote DNA damage repair and suppress dedifferentiation in breast cancer	14
Insights into the formation and diversification of a novel chiropteran wing membrane from embryonic development	14
De novo genome assembly of white clover (Trifolium repens L.) reveals the role of copy number variation in rapid environmental adaptation	14
Unveiling cell-type-specific microRNA networks through alternative polyadenylation in glioblastoma	14
Publisher Correction: Female behavior drives the formation of distinct social structures in C57BL/6J versus wild-derived outbred mice in field enclosures	14
G-quadruplexes as pivotal components of cis-regulatory elements in the human genome	14
Acute cannabinoids impair association learning via selectively enhancing synaptic transmission in striatonigral neurons	14
Exonuclease editor promotes precision of gene editing in mammalian cells	14
The genome and sex-dependent responses to temperature in the common yellow butterfly, Eurema hecabe	13
Systematic prediction of degrons and E3 ubiquitin ligase binding via deep learning	13
Genome-wide association mapping reveals genes underlying population-level metabolome diversity in a fungal crop pathogen	13
Rotating culture regulates the formation of HepaRG-derived liver organoids via YAP translocation	13
The evolution of ectomycorrhizal symbiosis and host-plant switches are the main drivers for diversification of Amanitaceae (Agaricales, Basidiomycota)	13
A novel plant-fungal association reveals fundamental sRNA and gene expression reprogramming at the onset of symbiosis	13
The steroid hormone estriol (E3) regulates epigenetic programming of fetal mouse brain and reproductive tract	13
Intricate response dynamics enhances stimulus discrimination in the resource-limited C. elegans chemosensory system	13
Cytological, transcriptome and miRNome temporal landscapes decode enhancement of rice grain size	13
Single-cell genomics unveils a canonical origin of the diverse mitochondrial genomes of euglenozoans	13
Differentiation is accompanied by a progressive loss in transcriptional memory	13
Rapid evolution of mitochondrion-related genes in haplodiploid arthropods	13
An epilepsy-causing mutation leads to co-translational misfolding of the Kv7.2 channel	13
Nanoscale characterization of drug-induced microtubule filament dysfunction using super-resolution microscopy	13
Lentiviral in situ targeting of stem cells in unperturbed intestinal epithelium	13
Contaminants from dredged sediments alter the transcriptome of Manila clam and induce shifts in microbiota composition	13
Phylogenomics resolves the higher-level phylogeny of herbivorous eriophyoid mites (Acariformes: Eriophyoidea)	13
Light sampling behaviour regulates circadian entrainment in mice	13
Phylogenomic approaches untangle early divergences and complex diversifications of the olive plant family	13
Intra-colony venom diversity contributes to maintaining eusociality in a cooperatively breeding ant	13
Epigenetic regulation of 5α reductase-1 underlies adaptive plasticity of reproductive function and pubertal timing	12
Integrated transcriptomic analysis reveals evolutionary and developmental characteristics of tendon ossification in teleost	12
Chromatin architecture reveals cell type-specific target genes for kidney disease risk variants	12
A systematic review of the development and application of home cage monitoring in laboratory mice and rats	12
DNA methylation of exercise-responsive genes differs between trained and untrained men	12
Selection on the promoter regions plays an important role in complex traits during duck domestication	12
Distinct hybridization modes in wide- and narrow-ranged lineages of Causonis (Vitaceae)	12
Population transcriptogenomics highlights impaired metabolism and small population sizes in tree frogs living in the Chernobyl Exclusion Zone	12
Synthetic Micrographs of Bacteria (SyMBac) allows accurate segmentation of bacterial cells using deep neural networks	12
Chromosome-level assemblies from diverse clades reveal limited structural and gene content variation in the genome of Candida glabrata	12
Large-scale genomic analysis reveals the genetic cost of chicken domestication	12
1,6-Hexanediol regulates angiogenesis via suppression of cyclin A1-mediated endothelial function	12
Formation and characterization of BMP2/GDF5 and BMP4/GDF5 heterodimers	12
Regulation of Miwi-mediated mRNA stabilization by Ck137956/Tssa is essential for male fertility	12
Holistic description of new deep sea megafauna (Cephalopoda: Cirrata) using a minimally invasive approach	12
GnRH-driven FTO-mediated RNA m6A modification promotes gonadotropin synthesis and secretion	12
The chromosome-scale genome assembly for the West Nile vector Culex quinquefasciatus uncovers patterns of genome evolution in mosquitoes	12
Genome-wide comparative methylation analysis reveals the fate of germ stem cells after surrogate production in teleost	12
Lactoferrin deficiency during lactation increases the risk of depressive-like behavior in adult mice	12
MAPK-dependent control of mitotic progression in S. pombe	12
Sexually dimorphic methylation patterns characterize the placenta and blood from extremely preterm newborns	12