BMC Biology

Article	Citations
An updated tribal classification of Lamiaceae based on plastome phylogenomics	143
Plastid phylogenomic insights into relationships of all flowering plant families	128
Plasma membrane integrity: implications for health and disease	112
ONTbarcoder and MinION barcodes aid biodiversity discovery and identification by everyone, for everyone	97
Hidden genomic features of an invasive malaria vector, Anopheles stephensi, revealed by a chromosome-level genome assembly	87
Winter is coming: the future of cryopreservation	78
Comparison of 15 dinoflagellate genomes reveals extensive sequence and structural divergence in family Symbiodiniaceae and genus Symbiodinium	75
FGF-2 promotes angiogenesis through a SRSF1/SRSF3/SRPK1-dependent axis that controls VEGFR1 splicing in endothelial cells	64
Prokaryotic virus host predictor: a Gaussian model for host prediction of prokaryotic viruses in metagenomics	62
Genome sequencing sheds light on the contribution of structural variants to Brassica oleracea diversification	57
Putative ligand binding sites of two functionally characterized bark beetle odorant receptors	56
Long-term live imaging and multiscale analysis identify heterogeneity and core principles of epithelial organoid morphogenesis	56
The hard clam genome reveals massive expansion and diversification of inhibitors of apoptosis in Bivalvia	54
Global population genetic structure and demographic trajectories of the black soldier fly, Hermetia illucens	53
Fluid shear stress enhances T cell activation through Piezo1	52
Reorganization of the 3D chromatin architecture of rice genomes during heat stress	51
Long-term persistence of crAss-like phage crAss001 is associated with phase variation in Bacteroides intestinalis	50
Autochthonous faecal viral transfer (FVT) impacts the murine microbiome after antibiotic perturbation	50
Characterization of a novel type of carbonic anhydrase that acts without metal cofactors	49
Evolutionary analyses of the gasdermin family suggest conserved roles in infection response despite loss of pore-forming functionality	48
Conventional laboratory housing increases morbidity and mortality in research rodents: results of a meta-analysis	48
Sphenodontian phylogeny and the impact of model choice in Bayesian morphological clock estimates of divergence times and evolutionary rates	47
The genome of a wild Medicago species provides insights into the tolerant mechanisms of legume forage to environmental stress	46
Paxillin mediates ATP-induced activation of P2X7 receptor and NLRP3 inflammasome	43
Transposon-induced epigenetic silencing in the X chromosome as a novel form of dmrt1 expression regulation during sex determination in the fighting fish	43

Characterizing RNA stability genome-wide through combined analysis of PRO-seq and RNA-seq data	42
The transposable element-rich genome of the cereal pest Sitophilus oryzae	42
Comprehensive transcriptome and methylome analysis delineates the biological basis of hair follicle development and wool-related traits in Merino sheep	40
Sorting and packaging of RNA into extracellular vesicles shape intracellular transcript levels	40
Phylogenomic approaches untangle early divergences and complex diversifications of the olive plant family	40
Towards open, reliable, and transparent ecology and evolutionary biology	39
Development of an efficient and precise adenine base editor (ABE) with expanded target range in allotetraploid cotton (Gossypium hirsutum)	39
m5U-SVM: identification of RNA 5-methyluridine modification sites based on multi-view features of physicochemical features and distributed representation	38
Measuring and modeling energy and power consumption in living microbial cells with a synthetic ATP reporter	38
Rapid protein evolution, organellar reductions, and invasive intronic elements in the marine aerobic parasite dinoflagellate Amoebophrya spp	38
Native-like membrane models of E. coli polar lipid extract shed light on the importance of lipid composition complexity	37
DNA methyltransferase 3a mediates developmental thermal plasticity	36
Comparative analysis of morabine grasshopper genomes reveals highly abundant transposable elements and rapidly proliferating satellite DNA repeats	34
Modelling the Wolbachia incompatible insect technique: strategies for effective mosquito population elimination	34
A versatile contribution of both aminopeptidases N and ABC transporters to Bt Cry1Ac toxicity in the diamondback moth	33
Deconvolution of cellular subsets in human tissue based on targeted DNA methylation analysis at individual CpG sites	33
Articulating the “stem cell niche” paradigm through the lens of non-model aquatic invertebrates	33
Segmentation, tracking and cell cycle analysis of live-cell imaging data with Cell-ACDC	32
Comparative 3D genome architecture in vertebrates	32
A primary cell wall cellulose-dependent defense mechanism against vascular pathogens revealed by time-resolved dual transcriptomics	32
Gregarine single-cell transcriptomics reveals differential mitochondrial remodeling and adaptation in apicomplexans	31
Oxidative stress mediates thalidomide-induced pain by targeting peripheral TRPA1 and central TRPV4	31
Engineered sex ratio distortion by X-shredding in the global agricultural pest Ceratitis capitata	30
Satellitome comparison of two oedipodine grasshoppers highlights the contingent nature of satellite DNA evolution	30
Large-scale genomic analysis reveals the genetic cost of chicken domestication	29
Genomic analysis of field pennycress (Thlaspi arvense) provides insights into mechanisms of adaptation to high elevation	29
A unified evolutionary origin for the ubiquitous protein transporters SecY and YidC	29
Dynamic and reversible DNA methylation changes induced by genome separation and merger of polyploid wheat	28
LocalZProjector and DeProj: a toolbox for local 2D projection and accurate morphometrics of large 3D microscopy images	28
Single-cell RNA-seq reveals a concomitant delay in differentiation and cell cycle of aged hematopoietic stem cells	28
Prediction of protein solubility based on sequence physicochemical patterns and distributed representation information with DeepSoluE	28
DHA alleviates diet-induced skeletal muscle fiber remodeling via FTO/m6A/DDIT4/PGC1α signaling	28
MATISSE: a method for improved single cell segmentation in imaging mass cytometry	28
Monophyletic blowflies revealed by phylogenomics	28
Single-cell resolution landscape of equine peripheral blood mononuclear cells reveals diverse cell types including T-bet+ B cells	27
The mitochondrially-localized nucleoside diphosphate kinase D (NME4) is a novel metastasis suppressor	27
Aerodynamics and motor control of ultrasonic vocalizations for social communication in mice and rats	27
Divergent camptothecin biosynthetic pathway in Ophiorrhiza pumila	27
Verticillium dahliae CFEM proteins manipulate host immunity and differentially contribute to virulence	27
Symbiont transmission in marine sponges: reproduction, development, and metamorphosis	27
An essential vesicular-trafficking phospholipase mediates neutral lipid synthesis and contributes to hemozoin formation in Plasmodium falciparum	26
TORC1 regulates the transcriptional response to glucose and developmental cycle via the Tap42-Sit4-Rrd1/2 pathway in Saccharomyces cerevisiae	26
Spatial and temporal heterogeneity in the lineage progression of fine oligodendrocyte subtypes	26
The gut symbiont Sphingomonas mediates imidacloprid resistance in the important agricultural insect pest Aphis gossypii Glover	26
Resilin matrix distribution, variability and function in Drosophila	25
Regenerating zebrafish scales express a subset of evolutionary conserved genes involved in human skeletal disease	25
Genome-scale CRISPR screening at high sensitivity with an empirically designed sgRNA library	25
Stomatal conductance limited the CO2 response of grassland in the last century	25
Crystal structure of the yeast heterodimeric ADAT2/3 deaminase	25
Mangroves are an overlooked hotspot of insect diversity despite low plant diversity	25

LEA motifs promote desiccation tolerance in vivo	24
Neuronal cell-based high-throughput screen for enhancers of mitochondrial function reveals luteolin as a modulator of mitochondria-endoplasmic reticulum coupling	24
Pathologic tau conformer ensembles induce dynamic, liquid-liquid phase separation events at the nuclear envelope	24
Large-scale transcriptomics to dissect 2 years of the life of a fungal phytopathogen interacting with its host plant	24
The genome of the zoonotic malaria parasite Plasmodium simium reveals adaptations to host switching	24
The effect of calorie intake, fasting, and dietary composition on metabolic health and gut microbiota in mice	24
Both Conifer II and Gnetales are characterized by a high frequency of ancient mitochondrial gene transfer to the nuclear genome	24
Deep learning-based behavioral profiling of rodent stroke recovery	24
Identifying disease-related microbes based on multi-scale variational graph autoencoder embedding Wasserstein distance	24
The pangenome of the wheat pathogen Pyrenophora tritici-repentis reveals novel transposons associated with necrotrophic effectors ToxA and ToxB	24
Large-scale genomic analysis of antimicrobial resistance in the zoonotic pathogen Streptococcus suis	24
Single-cell spatial transcriptomic analysis reveals common and divergent features of developing postnatal granule cerebellar cells and medulloblastoma	24
Epistasis and evolution: recent advances and an outlook for prediction	24
Waking experience modulates sleep need in mice	23
Time of day as a critical variable in biology	23
Boundaries potentiate polycomb response element-mediated silencing	23
H3K27 modifiers regulate lifespan in C. elegans in a context-dependent manner	23
Phylogenomic analysis of Syngnathidae reveals novel relationships, origins of endemic diversity and variable diversification rates	23
Beyond Drosophila: resolving the rapid radiation of schizophoran flies with phylotranscriptomics	23
Dynamic genetic differentiation drives the widespread structural and functional convergent evolution of snake venom proteinaceous toxins	22
miR-31-5p regulates cold acclimation of the wood-boring beetle Monochamus alternatus via ascaroside signaling	22
Mapping the past, present and future research landscape of paternal effects	22
Molecular action of larvicidal flavonoids on ecdysteroidogenic glutathione S-transferase Noppera-bo in Aedes aegypti	22
Ultrastructural and molecular analysis of the origin and differentiation of cells mediating brittle star skeletal regeneration	22
Sexual conflict drives micro- and macroevolution of sexual dimorphism in immunity	22
Short single-stranded DNAs with putative non-canonical structures comprise a new class of plasma cell-free DNA	22
Predicting the hosts of prokaryotic viruses using GCN-based semi-supervised learning	22
Differing effects of size and lifestyle on bone structure in mammals	21
Genome of the pincer wasp Gonatopus flavifemur reveals unique venom evolution and a dual adaptation to parasitism and predation	21
ERF49 mediates brassinosteroid regulation of heat stress tolerance in Arabidopsis thaliana	21
20E-mediated regulation of BmKr-h1 by BmKRP promotes oocyte maturation	21
A phenomics approach for antiviral drug discovery	21
Self-organising human gonads generated by a Matrigel-based gradient system	21
Rearrangement and domestication as drivers of Rosaceae mitogenome plasticity	21
The genome of the stable fly, Stomoxys calcitrans, reveals potential mechanisms underlying reproduction, host interactions, and novel targets for pest control	21
Highly flexible metabolism of the marine euglenozoan protist Diplonema papillatum	21
Natural food intake patterns have little synchronizing effect on peripheral circadian clocks	21
Sensory adaptations reshaped intrinsic factors underlying morphological diversification in bats	21
Cotton D genome assemblies built with long-read data unveil mechanisms of centromere evolution and stress tolerance divergence	21
Cell culture-based production and in vivo characterization of purely clonal defective interfering influenza virus particles	21
Mutagenesis of the odorant receptor co-receptor (Orco) reveals severe olfactory defects in the crop pest moth Helicoverpa armigera	20
Enhancer-promoter interaction maps provide insights into skeletal muscle-related traits in pig genome	20
Publication bias impacts on effect size, statistical power, and magnitude (Type M) and sign (Type S) errors in ecology and evolutionary biology	20
The ESCRT-III isoforms CHMP2A and CHMP2B display different effects on membranes upon polymerization	20
Impact of male trait exaggeration on sex-biased gene expression and genome architecture in a water strider	20
Mycobacterium leprae diversity and population dynamics in medieval Europe from novel ancient genomes	20
Engineered Cas12a-Plus nuclease enables gene editing with enhanced activity and specificity	20
A plastid phylogenomic framework for the palm family (Arecaceae)	20
The relationship between sternum variation and mode of locomotion in birds	20
MIEF1/2 orchestrate mitochondrial dynamics through direct engagement with both the fission and fusion machineries	20
Functional analyses of phosphatidylserine/PI(4)P exchangers with diverse lipid species and membrane contexts reveal unanticipated rules on lipid transfer	20
Protein kinase A controls yeast growth in visible light	20
Invasive snails, parasite spillback, and potential parasite spillover drive parasitic diseases of Hippopotamus amphibius in artificial lakes of Zimbabwe	20
Circulating miRNA repertoire as a biomarker of metabolic and reproductive states in rainbow trout	20
Developing long-term conservation priority planning for medicinal plants in China by combining conservation status with diversity hotspot analyses and climate change prediction	20
Indoleacrylic acid produced by Parabacteroides distasonis alleviates type 2 diabetes via activation of AhR to repair intestinal barrier	20
Chromosome-level genome assemblies of four wild peach species provide insights into genome evolution and genetic basis of stress resistance	20
Circadian rhythms in the plant host influence rhythmicity of rhizosphere microbiota	20
The H3K27M mutation alters stem cell growth, epigenetic regulation, and differentiation potential	19
Attractive and repulsive effects of sensory history concurrently shape visual perception	19
A neuromechanical model for Drosophila larval crawling based on physical measurements	19
Single-cell morphological characterization of CRH neurons throughout the whole mouse brain	19
A comparative methylome analysis reveals conservation and divergence of DNA methylation patterns and functions in vertebrates	19
Innate antiviral defense demonstrates high energetic efficiency in a bony fish	19
DNA methylation atlas and machinery in the developing and regenerating annelid Platynereis dumerilii	19
Mutant resources for functional genomics in Dictyostelium discoideum using REMI-seq technology	19
Visualizing extracellular vesicle biogenesis in gram-positive bacteria using super-resolution microscopy	19
Experimental demonstration of tethered gene drive systems for confined population modification or suppression	19
Adipoclast: a multinucleated fat-eating macrophage	19
The Venturia inaequalis effector repertoire is dominated by expanded families with predicted structural similarity, but unrelated sequence, to avirulence proteins from other plant-pathogenic fungi	19
Genetic dissection of the mitochondrial lipoylation pathway in yeast	19
Genomics and transcriptomics yields a system-level view of the biology of the pathogen Naegleria fowleri	19
Improved biomarker discovery through a plot twist in transcriptomic data analysis	19
The dorsoanterior brain of adult amphioxus shares similarities in expression profile and neuronal composition with the vertebrate telencephalon	19
The amygdala modulates prepulse inhibition of the auditory startle reflex through excitatory inputs to the caudal pontine reticular nucleus	19
Ionotropic receptors in the turnip moth Agrotis segetum respond to repellent medium-chain fatty acids	19
A cell-to-patient machine learning transfer approach uncovers novel basal-like breast cancer prognostic markers amongst alternative splice variants	18
Sea urchin larvae utilize light for regulating the pyloric opening	18
To kill or to be killed: pangenome analysis of Escherichia coli strains reveals a tailocin specific for pandemic ST131	18
Molecular drivers of insecticide resistance in the Sahelo-Sudanian populations of a major malaria vector Anopheles coluzzii	18

Apoptosis is not conserved in plants as revealed by critical examination of a model for plant apoptosis-like cell death	18
Transcriptional atlas analysis from multiple tissues reveals the expression specificity patterns in beef cattle	18
Input from torus longitudinalis drives binocularity and spatial summation in zebrafish optic tectum	18
Fruit bats adjust their foraging strategies to urban environments to diversify their diet	18
Single-cell DNA and RNA sequencing reveals the dynamics of intra-tumor heterogeneity in a colorectal cancer model	18
The Wnt-specific astacin proteinase HAS-7 restricts head organizer formation in Hydra	18
Genome plasticity in Paramecium bursaria revealed by population genomics	18
Zinc antagonizes iron-regulation of tyrosine hydroxylase activity and dopamine production in Drosophila melanogaster	18
Asymmetric expansions of FT and TFL1 lineages characterize differential evolution of the EuPEBP family in the major angiosperm lineages	18
Inherent constraints on a polyfunctional tissue lead to a reproduction-immunity tradeoff	18
Experimental infection with the hookworm, Necator americanus, is associated with stable gut microbial diversity in human volunteers with relapsing multiple sclerosis	18
Transposable element expansion and low-level piRNA silencing in grasshoppers may cause genome gigantism	18
Nutritional control regulates symbiont proliferation and life history in coral-dinoflagellate symbiosis	18
Feedback inhibition of AMT1 NH4+-transporters mediated by CIPK15 kinase	18
Analysis of urinary exosomal metabolites identifies cardiovascular risk signatures with added value to urine analysis	18
The role of the odorant receptors in the formation of the sensory map	18
Bulk and single-cell characterisation of the immune heterogeneity of atherosclerosis identifies novel targets for immunotherapy	18
Complete representation of a tapeworm genome reveals chromosomes capped by centromeres, necessitating a dual role in segregation and protection	18
Hematopoietic differentiation is characterized by a transient peak of entropy at a single-cell level	18
The stem rust fungus Puccinia graminis f. sp. tritici induces centromeric small RNAs during late infection that are associated with genome-wide DNA methylation	18
Novel high-resolution targeted sequencing of the cervicovaginal microbiome	17
Characterization of the dynamics and variability of neuronal subtype responses during growth, degrowth, and regeneration of Nematostella vectensis	17
Combined protein and transcript single-cell RNA sequencing in human peripheral blood mononuclear cells	17
Genome-wide annotation of protein-coding genes in pig	17
Anaerobic derivates of mitochondria and peroxisomes in the free-living amoeba Pelomyxa schiedti revealed by single-cell genomics	17
APOBEC3 mutational signatures are associated with extensive and diverse genomic instability across multiple tumour types	17
Phylotranscriptomics points to multiple independent origins of multicellularity and cellular differentiation in the volvocine algae	17
A universal power law for modelling the growth and form of teeth, claws, horns, thorns, beaks, and shells	17
The interactome of CLUH reveals its association to SPAG5 and its co-translational proximity to mitochondrial proteins	17
Vickermania gen. nov., trypanosomatids that use two joined flagella to resist midgut peristaltic flow within the fly host	17
Divergent CPEB prion-like domains reveal different assembly mechanisms for a generic amyloid-like fold	17
Single-cell RNA sequencing of the retina in a model of retinitis pigmentosa reveals early responses to degeneration in rods and cones	17
The mutational landscape of human olfactory G protein-coupled receptors	17
Rat PRDM9 shapes recombination landscapes, duration of meiosis, gametogenesis, and age of fertility	17
An IGF1-expressing endometrial stromal cell population is associated with human decidualization	17
Intradiol ring cleavage dioxygenases from herbivorous spider mites as a new detoxification enzyme family in animals	17
Deviations from temporal scaling support a stage-specific regulation for C. elegans postembryonic development	17
Snakes on a plain: biotic and abiotic factors determine venom compositional variation in a wide-ranging generalist rattlesnake	16
Current cancer driver variant predictors learn to recognize driver genes instead of functional variants	16
Long-term dynamics of the human oral microbiome during clinical disease progression	16
A polyketide synthase from Verticillium dahliae modulates melanin biosynthesis and hyphal growth to promote virulence	16
Unprecedented organelle genomic variations in morning glories reveal independent evolutionary scenarios of parasitic plants and the diversification of plant mitochondrial complexes	16
Taxonomy-aware, sequence similarity ranking reliably predicts phage–host relationships	16
Practical real-time MEG-based neural interfacing with optically pumped magnetometers	16
Modular evolution of secretion systems and virulence plasmids in a bacterial species complex	16
Monkeying around with venom: an increased resistance to α-neurotoxins supports an evolutionary arms race between Afro-Asian primates and sympatric cobras	16
Disruption of left-right axis specification in Ciona induces molecular, cellular, and functional defects in asymmetric brain structures	16
Flexible and stretchable polymer optical fibers for chronic brain and vagus nerve optogenetic stimulations in free-behaving animals	16
Krüppel-homolog 1 exerts anti-metamorphic and vitellogenic functions in insects via phosphorylation-mediated recruitment of specific cofactors	16
An optimized base editor with efficient C-to-T base editing in zebrafish	16
Microfluidic guillotine reveals multiple timescales and mechanical modes of wound response in Stentor coeruleus	16
The broad use of the Pm8 resistance gene in wheat resulted in hypermutation of the AvrPm8 gene in the powdery mildew pathogen	16
The evolution of pelvic canal shape and rotational birth in humans	15
A protocol for adding knowledge to Wikidata: aligning resources on human coronaviruses	15
A phylogenomic analysis of Limosilactobacillus reuteri reveals ancient and stable evolutionary relationships with rodents and birds and zoonotic transmission to humans	15
Combined pangenomics and transcriptomics reveals core and redundant virulence processes in a rapidly evolving fungal plant pathogen	15
Dynamics and structural changes of calmodulin upon interaction with the antagonist calmidazolium	15
The ATPase SRCAP is associated with the mitotic apparatus, uncovering novel molecular aspects of Floating-Harbor syndrome	15
Very long intergenic non-coding (vlinc) RNAs directly regulate multiple genes in cis and trans	15
Mixotrophic chemosynthesis in a deep-sea anemone from hydrothermal vents in the Pescadero Basin, Gulf of California	15
Conservation and trans-regulation of histone modification in the A and B subgenomes of polyploid wheat during domestication and ploidy transition	15
Age-related susceptibility to insulin resistance arises from a combination of CPT1B decline and lipid overload	15
Single-cell transcriptomics reveals the effect of PD-L1/TGF-β blockade on the tumor microenvironment	15
Lack of drug-induced post-retrieval amnesia for auditory fear memories in rats	15
A high-quality Buxus austro-yunnanensis (Buxales) genome provides new insights into karyotype evolution in early eudicots	15
Assessing optimal: inequalities in codon optimization algorithms	15
Transcription-dependent confined diffusion of enzymes within subcellular spaces of the bacterial cytoplasm	14
Inheritance of the reduced mitochondria of Giardia intestinalis is coupled to the flagellar maturation cycle	14
A pair of long intergenic non-coding RNA LINC00887 variants act antagonistically to control Carbonic Anhydrase IX transcription upon hypoxia in tongue squamous carcinoma progression	14
Modelling spatiotemporal trends in the frequency of genetic mutations conferring insecticide target-site resistance in African mosquito malaria vector species	14
Gene losses may contribute to subterranean adaptations in naked mole-rat and blind mole-rat	14
BG-flow, a new flow cytometry tool for G-quadruplex quantification in fixed cells	14
Long non-coding RNA Tug1 modulates mitochondrial and myogenic responses to exercise in skeletal muscle	14
PACmn for improved optogenetic control of intracellular cAMP	14
Omission responses in local field potentials in rat auditory cortex	14
Screens in fly and beetle reveal vastly divergent gene sets required for developmental processes	14
CRISPR/Cas9-mediated gene knockout and interallelic gene conversion in human induced pluripotent stem cells using non-integrative bacteriophage-chimeric retrovirus-like particles	14
Channel nuclear pore protein 54 directs sexual differentiation and neuronal wiring of female reproductive behaviors in Drosophila	14
Genome-wide association reveals host-specific genomic traits in Escherichia coli	14
Co-option of the limb patterning program in cephalopod eye development	14
Caenorhabditis elegans exhibits positive gravitaxis	14
RNAlysis: analyze your RNA sequencing data without writing a single line of code	14
The testis-specific E3 ubiquitin ligase RNF133 is required for fecundity in mice	14
Selection shapes the landscape of functional variation in wild house mice	14
Do all mice smell the same? Chemosensory cues from inbred and wild mouse strains elicit stereotypic sensory representations in the accessory olfactory bulb	13
Chromosome-level assemblies from diverse clades reveal limited structural and gene content variation in the genome of Candida glabrata	13
Parental energy-sensing pathways control intergenerational offspring sex determination in the nematode Auanema freiburgensis	13
OLIG2 regulates lncRNAs and its own expression during oligodendrocyte lineage formation	13
Generation of multicellular spatiotemporal models of population dynamics from ordinary differential equations, with applications in viral infection	13
Systematic prediction of degrons and E3 ubiquitin ligase binding via deep learning	13
The adaptive benefit of evolved increases in hemoglobin-O2 affinity is contingent on tissue O2 diffusing capacity in high-altitude deer mice	13
CloneSifter: enrichment of rare clones from heterogeneous cell populations	13
Chromatin architecture reveals cell type-specific target genes for kidney disease risk variants	13
Colored visual stimuli evoke spectrally tuned neuronal responses across the central nervous system of zebrafish larvae	13
Integrative single-cell RNA-seq and ATAC-seq analysis of myogenic differentiation in pig	13