OOIR: Observatory of International Research

Papers

(The TQCC of Protein Engineering Design & Selection is 7. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-11-01 to 2024-11-01.)

Article	Citations
Protein-based lateral flow assays for COVID-19 detection	55
Evolution of β-lactamases and enzyme promiscuity	26
Engineering stable carbonic anhydrases for CO2 capture: a critical review	20
Masked inverse folding with sequence transfer for protein representation learning	17
The evolution and engineering of enzyme activity through tuning conformational landscapes	16
Design and engineering of artificial metalloproteins: from de novo metal coordination to catalysis	16
Engineering enzyme activity using an expanded amino acid alphabet	15
Linking thermodynamics and measurements of protein stability	15
Optimization of multi-site nicking mutagenesis for generation of large, user-defined combinatorial libraries	13
The stability and dynamics of computationally designed proteins	12
Generation of a nanobody against HER2 tyrosine kinase using phage display library screening for HER2-positive breast cancer therapy development	11
A fragment-based protein interface design algorithm for symmetric assemblies	11
The design and evolution of fluorescent protein-based sensors for monoatomic ions in biology	10
Breakthroughs in computational design methods open up new frontiers for de novo protein engineering	10
Non-canonical amino acids as a tool for the thermal stabilization of enzymes	9
Improved thermostability of proteinase K and recognizing the synergistic effect of Rosetta and FoldX approaches	9
Stabilization of the SARS-CoV-2 receptor binding domain by protein core redesign and deep mutational scanning	9
Molecular flexibility in computational protein design: an algorithmic perspective	8
Generation of a 100-billion cyclic peptide phage display library having a high skeletal diversity	8
Data-driven enzyme engineering to identify function-enhancing enzymes	7
Comprehensive mapping of SARS-CoV-2 peptide epitopes for development of a highly sensitive serological test for total and neutralizing antibodies	7
Computational design and experimental optimization of protein binders with prospects for biomedical applications	7
Protein engineering for natural product biosynthesis and synthetic biology applications	7
Structure-guided protein engineering of human cathepsin L for efficient collagenolytic activity	7