OOIR: Observatory of International Research

Papers

(The median citation count of Protein Engineering Design & Selection is 3. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-11-01 to 2024-11-01.)

Article	Citations
Protein-based lateral flow assays for COVID-19 detection	55
Evolution of β-lactamases and enzyme promiscuity	26
Engineering stable carbonic anhydrases for CO2 capture: a critical review	20
Masked inverse folding with sequence transfer for protein representation learning	17
The evolution and engineering of enzyme activity through tuning conformational landscapes	16
Design and engineering of artificial metalloproteins: from de novo metal coordination to catalysis	16
Engineering enzyme activity using an expanded amino acid alphabet	15
Linking thermodynamics and measurements of protein stability	15
Optimization of multi-site nicking mutagenesis for generation of large, user-defined combinatorial libraries	13
The stability and dynamics of computationally designed proteins	12
Generation of a nanobody against HER2 tyrosine kinase using phage display library screening for HER2-positive breast cancer therapy development	11
A fragment-based protein interface design algorithm for symmetric assemblies	11
Breakthroughs in computational design methods open up new frontiers for de novo protein engineering	10
The design and evolution of fluorescent protein-based sensors for monoatomic ions in biology	10
Non-canonical amino acids as a tool for the thermal stabilization of enzymes	9
Improved thermostability of proteinase K and recognizing the synergistic effect of Rosetta and FoldX approaches	9
Stabilization of the SARS-CoV-2 receptor binding domain by protein core redesign and deep mutational scanning	9
Molecular flexibility in computational protein design: an algorithmic perspective	8
Generation of a 100-billion cyclic peptide phage display library having a high skeletal diversity	8
Data-driven enzyme engineering to identify function-enhancing enzymes	7
Comprehensive mapping of SARS-CoV-2 peptide epitopes for development of a highly sensitive serological test for total and neutralizing antibodies	7
Computational design and experimental optimization of protein binders with prospects for biomedical applications	7
Protein engineering for natural product biosynthesis and synthetic biology applications	7
Structure-guided protein engineering of human cathepsin L for efficient collagenolytic activity	7
Engineering cellulases for conversion of lignocellulosic biomass	6

Recent developments in engineering protein–protein interactions using phage display	6
High-efficacy, high-manufacturability human VH domain antibody therapeutics from transgenic sources	6
Extended yeast surface display linkers enhance the enrichment of ligands in direct mammalian cell selections	6
Integrating dynamics into enzyme engineering	6
OUP accepted manuscript	6
DE-STRESS: a user-friendly web application for the evaluation of protein designs	5
Construction, characterization and crystal structure of a fluorescent single-chain Fv chimera	5
Physics-based approach to extend a de novo TIM barrel with rationally designed helix-loop-helix motifs	5
Thermostable D-amino acid decarboxylases derived from Thermotoga maritima diaminopimelate decarboxylase	4
Modifying pH-sensitive PCSK9/LDLR interactions as a strategy to enhance hepatic cell uptake of low-density lipoprotein cholesterol (LDL-C)	4
Design of functional intrinsically disordered proteins	3
Reducing substrate inhibition of malate dehydrogenase from Geobacillus stearothermophilus by C-terminal truncation	3
Enzyme redesign and genetic code expansion	3
The shortest path method (SPM) webserver for computational enzyme design	3
Improvement of Moloney murine leukemia virus reverse transcriptase thermostability by introducing a disulfide bridge in the ribonuclease H region	3
Rational engineering of an erythropoietin fusion protein to treat hypoxia	3
Cyan fluorescent proteins derived from mNeonGreen	3
Immortalization and functional screening of natively paired human T cell receptor repertoires	3
Engineering Candida boidinii formate dehydrogenase for activity with the non-canonical cofactor 3′-NADP(H)	3
Protein engineering approach to enhance activity assays of mono-ADP-ribosyltransferases through proximity	3
Antibody-mediated delivery of CRISPR-Cas9 ribonucleoproteins in human cells	3
Strategies for enriching and characterizing proteins with inhibitory properties on the yeast surface	3