OOIR: Observatory of International Research

Papers

(The median citation count of Protein Engineering Design & Selection is 2. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-03-01 to 2024-03-01.)

Article	Citations
Protein-based lateral flow assays for COVID-19 detection	49
Evolution of β-lactamases and enzyme promiscuity	20
Engineering stable carbonic anhydrases for CO2 capture: a critical review	14
Design and engineering of artificial metalloproteins: from de novo metal coordination to catalysis	13
Linking thermodynamics and measurements of protein stability	12
Generation of a nanobody against HER2 tyrosine kinase using phage display library screening for HER2-positive breast cancer therapy development	10
A fragment-based protein interface design algorithm for symmetric assemblies	10
Breakthroughs in computational design methods open up new frontiers for de novo protein engineering	9
Optimization of multi-site nicking mutagenesis for generation of large, user-defined combinatorial libraries	9
The design and evolution of fluorescent protein-based sensors for monoatomic ions in biology	9
The evolution and engineering of enzyme activity through tuning conformational landscapes	8
Stabilization of the SARS-CoV-2 receptor binding domain by protein core redesign and deep mutational scanning	8
Molecular flexibility in computational protein design: an algorithmic perspective	8
The stability and dynamics of computationally designed proteins	8
Generation of a 100-billion cyclic peptide phage display library having a high skeletal diversity	7
Computational design and experimental optimization of protein binders with prospects for biomedical applications	7
Comprehensive mapping of SARS-CoV-2 peptide epitopes for development of a highly sensitive serological test for total and neutralizing antibodies	7
Protein engineering for natural product biosynthesis and synthetic biology applications	6
Data-driven enzyme engineering to identify function-enhancing enzymes	6
Engineering enzyme activity using an expanded amino acid alphabet	6
Improved thermostability of proteinase K and recognizing the synergistic effect of Rosetta and FoldX approaches	6
Recent developments in engineering protein–protein interactions using phage display	5
Structure-guided protein engineering of human cathepsin L for efficient collagenolytic activity	5
DE-STRESS: a user-friendly web application for the evaluation of protein designs	4
OUP accepted manuscript	4

Engineering cellulases for conversion of lignocellulosic biomass	4
Modifying pH-sensitive PCSK9/LDLR interactions as a strategy to enhance hepatic cell uptake of low-density lipoprotein cholesterol (LDL-C)	3
Antibody-mediated delivery of CRISPR-Cas9 ribonucleoproteins in human cells	3
Construction, characterization and crystal structure of a fluorescent single-chain Fv chimera	3
High-efficacy, high-manufacturability human VH domain antibody therapeutics from transgenic sources	3
Integrating dynamics into enzyme engineering	3
Cyan fluorescent proteins derived from mNeonGreen	3
Masked inverse folding with sequence transfer for protein representation learning	3
Rational engineering of an erythropoietin fusion protein to treat hypoxia	3
Protein engineering approach to enhance activity assays of mono-ADP-ribosyltransferases through proximity	3
Extended yeast surface display linkers enhance the enrichment of ligands in direct mammalian cell selections	3
Increasing loop flexibility affords low-temperature adaptation of a moderate thermophilic malate dehydrogenase from Geobacillus stearothermophilus	2
Bispecific antibodies—effects of point mutations on CH3-CH3 interface stability	2
Improvement of Moloney murine leukemia virus reverse transcriptase thermostability by introducing a disulfide bridge in the ribonuclease H region	2
Immortalization and functional screening of natively paired human T cell receptor repertoires	2
Thermostable D-amino acid decarboxylases derived from Thermotoga maritima diaminopimelate decarboxylase	2
Substitution of distal and active site residues reduces product inhibition of E1 from Acidothermus Cellulolyticus	2