OOIR: Observatory of International Research

Papers

(The TQCC of Molecular & Cellular Toxicology is 2. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-04-01 to 2025-04-01.)

Article	Citations
Relationship between the levels of cord blood resistin, adiponectin, CD4 and CD8 and their influence on early neonatal outcomes	142
LncRNA SNHG12/miR-494-3p/CBX3 axis in diffuse large B-cell lymphoma	46
miR-29 family inhibited the proliferation and migration of lung cancer cells by targeting SREBP-1	27
Circ_0074027 regulates the progression of non-small cell lung cancer via miR-1304-5p/GJB2 axis	26
Omentin-1 ameliorates oxidative stress in model of diabetic ophthalmopathy via the promotion of AMPK function	26
Korean red ginseng extract exploits NF-κB to promote wound repair and protein expression in keratinocytes	17
The importance of multi-omics approaches for the health assessment of freshwater ecosystems	17
Pratensein glycoside attenuates respiratory syncytial virus infection-induced oxidative and inflammatory injury via TGF-β signaling pathway	15
S-ketamine promotes autophagy and alleviates neuropathic pain by inhibiting PI3K/Akt/mTOR signaling pathway	15
Immunoredox model for interpretation and prediction of human diseases	12
Influences of environmentally hazardous substances on atopic dermatitis: a review	10
HOXA11-AS/miR-208-3p/ETS1 axis modulates osteogenic differentiation in bone marrow-derived mesenchymal stem cells	9
Induction of glioblastoma invasion triggered by system Xc−-mediated glutamate release	9
Long non-coding RNA DIRC3 suppresses trophoblast invasion in preeclampsia via upregulating HOXD10	9
Dexmedetomidine repairs behavioral deficits through miR-365a-3p/G3BP2 axis and Nrf2/Keap1 signaling pathway in traumatic brain injury	9
Efficacy of urinary trypsin inhibitor in the treatment of rats with severe sepsis and its effects on coagulation and immunity	8
The effects of dantrolene and 2-aminoethoxydiphenyl borate (2-APB) on arsenic-induced osteoporosis	8
Correction: Cardiac biomarkers and detection methods for myocardial infarction	7
No association of prion protein gene (PRNP) polymorphisms with susceptibility to the pandemic 2009 swine flu	7
KLF4 overexpression facilitates proliferation and represses apoptosis of granulosa cells in polycystic ovary syndrome	6
Ethyl acetate layer of a methanol extract from Aquilaria crassna promotes oxidative stress-mediated apoptosis in non-small-cell lung cancer cells	6
Dexmedetomidine promotes autophagy and apoptosis of colon cancer cells by activating endoplasmic reticulum (ER) stress-mediated PERK/eIF2α/ATF4 signaling pathway	6
GPD1 relieves the proliferation, migration and invasion abilities of oral cancer cells by inhibiting mitochondrial function	6
Tolylfluanid induces developmental toxicity via liver dysfunction in zebrafish embryos	6
Nuclear translocation of β-catenin and migration of arecoline-induced oral cancer cells reduced by Taiwanin E via p-GSK3β downregulation	6

Oleamide–PDMS copolymer for coating urinary catheters with anti-adhesive and anti-biofilm properties	6
New insight of exercise on dementia; combinatory effects of physical and cognitive exercise	6
Anti-melanogenic effects of porcine placenta peptides through inhibition of tyrosinase expression and activity	6
Long non-coding RNA NONHSAT217600.1 is involved in the regulation of neodymium oxide-induced cytotoxicity in 16HBE cells	6
The efficacy of Plantago asiatica L. water extract on lipid metabolism in a high-fat diet-induced obese C57BL/6 mice	6
Long noncoding RNA MAFG-AS1 enhances proliferation, invasion, and epithelial–mesenchymal transition of melanoma cells through promoting KIT expression by competitively binding to miR-331-3p	6
CircNFIX promotes stemness and evasion of phagocytosis in glioma stem cells by sponging miR-449a to upregulate the expression of CD47	5
Oleuropein induces apoptosis in colorectal tumor spheres via mitochondrial fission	5
Beta-naphthoflavone increases the differentiation of osteoblasts and suppresses adipogenesis in human adipose derived stem cells involving STAT3 pathway	5
Comparative RNA-seq analysis and ceRNA network of genistein-treated GT1-7 neurons	5
Zearalenone activates GnRH neurons related to central precocious puberty by regulating microRNA-384/GPER signaling	5
Investigation on arrhythmogenic potential of phenanthrene using human induced pluripotent stem cell-derived cardiomyocytes	5
Core fucosylation of maternal milk N-glycan prevents intestinal inflammation by regulating Treg/Th17 balance in infant gut microbiota	4
Anti-proliferation and pro-apoptosis effects of miR-582-5p in chronic lymphocytic leukemia via targeting HNRNPA1 and suppression of NF-κB	4
Polyphyllin I combined with doxorubicin shows chemosensitization effect in vivo and reduces immunotoxicity of doxorubicin	4
Protective effects of Dioscorea polystachya ethanol extracts against lead acetate-induced oxidative DNA damage in MRC-5 cells	4
Comparative toxicity of polyhexamethylene guanidine phosphate in three strains of rats	4
Subcutaneous toxicity of melittin-dKLA in ICR mice	4
Transcriptome dynamics in benzo[a]pyrene exposed Hydra	4
MiR-214 inhibits apoptosis in thyroid epithelial follicular cells induced by amiodarone through the FASL/MAPK pathway	4
TRIM65 regulates prostate cancer cell growth and stemness through the WNT/β-catenin axis	4
Sensitive-stage embryo irradiation affects embryonic neuroblasts and adult motor function	4
In vitro evaluation of antioxidant activity and biocompatibility of caffeic acid phenethyl ester loaded in polymeric micelles	4
iTRAQ-based proteomics analysis of diethylstilbestrol induced dysfunction of testicular gubernaculum development in mouse	4
Knockdown of hsa_circ_0001964 inhibits hepatocellular carcinoma cell proliferation by inactivating PI3K/AKT signaling pathway	3
E2F1-induced PROX1-AS1 contributes to cell growth by regulating miR-424-5p/CPEB2 pathway in endometrial carcinoma	3
Screening of serum exosome markers for colorectal cancer based on Boruta and multi-cluster feature selection algorithms	3
Cytotoxicity-reducing and anti-inflammatory effects of a natural herb mixture extract	3
Correction to: Binding of silver nanowaste using jellyfish immune reaction extract and an assessment of aquatic toxicity	3
Anti-tumor effect of novel amino acid Schiff base nickel (II) complexes on oral squamous cell carcinoma cells (CAL-27) in vitro	3
Transcriptional responses in Ecklonia cava to short-term exposure to polycyclic aromatic hydrocarbons	3
MiR-370-3p aggravates blood–brain barrier injury and neuron apoptosis by targeting SMURF1 to activate the TLR4/MyD88/NF-κB signaling in sepsis-associated encephalopathy	3
HDAC3 deacetylates H3K27ac and H3K9ac on the TrkC promoter to exacerbate sevoflurane-induced neurotoxicity	3
Protective effect of Acer palmatum Thunb. leaf extract on mice with steroid-induced ocular hypertension	3
Ubiquitin ligase CHIP regulates neurological functional recovery after intracerebral hemorrhage through ubiquitination modification of FOXO1	3
The antitumor effect of natural killer cells against hepatocellular carcinoma through CXCL9	3
Curcumin suppresses oxidative stress via regulation of ROS/NF-κB signaling pathway to protect retinal vascular endothelial cell in diabetic retinopathy	3
Hyaluronic acid suppresses the effect of di-(2-ethylhexyl) phthalate in HaCaT keratinocytes	3
Correction to: Nitric oxide-caused rabbit chondrocyte apoptosis is linked to cytoskeletal protein proteolysis anomaly through intracellular JNK and ERK signal pathways	3
Anticancer activity of herbal formula Jisilhaebaekgyeji-Tang against human breast cancer cells and its mechanism	3
Mitochondrial dysfunction is underlying fluoroquinolone toxicity: an integrated mitochondrial toxicity assessment	3
Silibinin alleviates DNA damage, mitochondrial dysfunction, and apoptosis caused by oxidative stress in human retinal pigment epithelial cells	3
Association of expression of GADD family genes and apoptosis in human kidney proximal tubular (HK-2) cells exposed to nephrotoxic drugs	3
Comparison of the cytotoxicity of bisphenol A and its analogs on human placental BeWo cells	3
Transmembrane protein 106C accelerates the progression of breast cancer through the activation of PI3K/AKT/mTOR signaling	3
Environmental antibiotic emissions and their residual impact on livestock farming	3
Up-regulation of PKCα and δ during beating cardiomyocyte differentiation of P19CL6 cells with suppressed apoptotic cell populations	3
Iridin abrogates LPS-induced inflammation in L6 skeletal muscle cells by inhibiting NF-κB and MAPK signaling pathway	3
Osteopontin promotes microglia activation and aggravates neuromyelitis optica via interferon-gamma/nuclear factor kappa B/interleukin-12 signaling	3
FGD5-AS1 promotes growth and mobility of trophoblast cells by regulating IGF2 via sponging miR-16-5p in pre-eclampsia	3

Study the effect of crocin on the expression of PAX2 and WT1 genes in renal tissues and serum levels of NGAL and cystatin C in cadmium-treated rats	3
Madecassic acid protects human periodontal ligament fibroblasts against hydrogen peroxide-induced cell damage by maintaining mitochondrial membrane potential	3
Combined treatment of ginsenoside Rg2 and piceatannol mixture reduces the apoptosis and DNA damage induced by UVB in HaCaT cells	2
Ursolic acid inhibits autophagy-dependent neuronal cell death by reducing oxidative stress levels in an in vitro model of Parkinson’s disease	2
Integrated analysis of miRNA and mRNA expression profiles in diabetic mouse kidney treated to Korean Red Ginseng	2
Terrestrosin D inhibits invasion and induces apoptosis through inhibition of STAT3 in anaplastic thyroid carcinoma	2
Novel data archival system for multi-omics data of human exposure to harmful substances	2
Molecular targets of histone deacetylase inhibitors in neurodegeneration and neuroprotection	2
The cytotoxic effects of bisphenol A alternatives in human lung fibroblast MRC5 cells	2
Relationship between Th17 cell proportion and IL-17/-18 levels and disease progression in patients with multiple myeloma	2
A cell model for evaluating mitochondrial damage in cardiomyocytes	2
Dihydrotanshinone I ameliorated angiotensin II-induced mitochondrial damage and oxidative stress in vascular smooth muscle cells	2
Circ_0003204 downregulation protected vascular smooth muscle cells from ox-LDL-induced injury by acting on miR-637/FOSL2 axis	2
CircSLCO3A1 depletion ameliorates lipopolysaccharide-induced inflammation and apoptosis of human pulmonary alveolar epithelial cells through the miR-424-5p/HMGB3 pathway	2
CircKLHL2 mitigates septic lung injury via circKLHL2-miR-338-3p-ATF6 ceRNA pathway	2
A method to measure the receptor-mediated Ca2+ transients in non-adherent THP-1 monocytes using gelatin methacryloyl for immobilization in a bath perfusion system	2
The role of pulmonary ORCC and CLC-2 channels in the response to oxidative stress	2
Dietary flavonoids protect human brain microvascular endothelial cell from oxidative stress-induced dysfunction	2
CircBLNK regulates tumor proliferation and apoptosis by miR-578/ING5 axis in non-small cell lung cancer	2
3D structural analysis of aptamer and diagnostic platforms for detecting hepatocellular carcinoma	2
Network-based toxicogenomic approach to explore oral benzo(a)pyrene exposure effect on respiratory system	2
Phenotypic and functional alterations of bone marrow MSCs exposed to multiple myeloma cells	2
USP13 promotes proliferation and angiogenesis of diffuse large B-cell lymphoma cells by promoting MCL-1 expression	2
Combining use of phillyrin and autophagy blocker exerts suppressive effect on nasopharyngeal carcinoma cell malignancy and autophagy via AMPK/mTOR/p70s6k signaling pathway	2
Gene expression related to lung cancer altered by PHMG-p treatment in PBTE cells	2
Long intergenic non-protein coding RNA 1436 accelerates cell proliferation, migration and adhesion properties of the MUM-2B cell line via microRNA-513a-5p/CUG Triplet repeat-binding protein 1 axis to	2
Liquiritin inhibits TGF-β1-induced epithelial mesenchymal transition and extracellular matrix deposition in human renal proximal tubular epithelial cells by suppressing the MAPK signaling	2
STAMP2 alleviates microglial neurotoxicity by inhibiting LPS-induced NF-κB activation	2
Antigrowth effects of Kaempferia parviflora extract enriched in anthocyanidins on human ovarian cancer cells through Ca2+-ROS overload and mitochondrial dysfunction	2
Long non-coding RNA DLX6-AS1 accelerates lipopolysaccharides-induced human AC16 cardiomyocytes apoptosis by regulating miR-497/CaSR axis	2
Nrf2 suppresses erastin-induced ferroptosis through activating system Xc(-) in ovarian cancer	2
Effects of rifampicin on hepatic antioxidant enzymes in PXR and CAR double humanized mice	2
Anti-inflammatory activity of Akebia quinata D. extracts by inhibiting MAPK and NF-κB signaling pathways in LPS-induced RAW 264.7 cells according to extraction solvents	2
NEAT1 promotes keratinocyte migration and proliferation during wound healing by regulating miR-26a-5p/LGR4 axis	2
LINC00174 targeting miR-486-5p/EIF5A2 is an oncogenic driver in oral squamous cell carcinoma	2
Knockdown of UHRF1 ameliorates high glucose-induced podocyte injury by activating SIRT4	2
Salvia microphylla essential oil reduces cell viability in cisplatin-resistant clear cell type ovarian cancer cells caused by mitochondrial dysfunction	2
Coal dust exposure induces proliferation and migration of human bronchial epithelial cells	2
Anti-inflammatory and relaxation effects of Ulmus pumilla L. on EGF-inflamed bronchial epithelial and asthmatic bronchial smooth muscle cells	2
Review of synergistic anticancer effects of natural compounds combined with conventional therapeutics against chemoresistance and progression of pancreatic cancer	2
MicroRNA-29b-3p reduces cisplatin resistance in non-small cell lung cancer by targeting myeloid cell leukemia-1	2
Identification of chromosomal type II toxin–antitoxin system from plant pathogenic Pseudomonas cichorii JBC 1	2
WTAP accelerates keloids formation by mediating m6A modification of HOXA5 to suppress p53 pathway	2
Inhibiting poly (ADP-ribose) polymerase 1 activation alleviates acetaminophen-induced acute liver injury in mice	2