OOIR: Observatory of International Research

Papers

(The TQCC of Molecular & Cellular Toxicology is 3. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-06-01 to 2026-06-01.)

Article	Citations
Anti-tumor effect of novel amino acid Schiff base nickel (II) complexes on oral squamous cell carcinoma cells (CAL-27) in vitro	50
Long non-coding RNA DIRC3 suppresses trophoblast invasion in preeclampsia via upregulating HOXD10	38
Oleamide–PDMS copolymer for coating urinary catheters with anti-adhesive and anti-biofilm properties	20
STAT3/NAV2 signaling promotes the progression of pulmonary fibrosis	19
Silibinin alleviates DNA damage, mitochondrial dysfunction, and apoptosis caused by oxidative stress in human retinal pigment epithelial cells	18
Immunoredox model for interpretation and prediction of human diseases	16
Cognitive and emotional dysregulation in T-cell-deficient mice: the role of hippocampal neurogenesis and synaptic plasticity	16
GPR1 ameliorates intermittent hypoxia-induced neuroinflammation in a mouse model of obstructive sleep apnea by regulating TAFA1-mediated ferroptosis	16
Therapeutic effect of Drynariae rhizoma water extract on DNCB-induced atopic dermatitis in mice	13
USP13 promotes proliferation and angiogenesis of diffuse large B-cell lymphoma cells by promoting MCL-1 expression	13
The importance of multi-omics approaches for the health assessment of freshwater ecosystems	13
A method to measure the receptor-mediated Ca2+ transients in non-adherent THP-1 monocytes using gelatin methacryloyl for immobilization in a bath perfusion system	12
Long intergenic non-protein coding RNA 1436 accelerates cell proliferation, migration and adhesion properties of the MUM-2B cell line via microRNA-513a-5p/CUG Triplet repeat-binding protein 1 axis to	10
CircBLNK regulates tumor proliferation and apoptosis by miR-578/ING5 axis in non-small cell lung cancer	10
YTHDC1 inhibits cell proliferation and angiogenesis in cervical cancer by regulating m6A modification of SOCS4 mRNA	9
Review of synergistic anticancer effects of natural compounds combined with conventional therapeutics against chemoresistance and progression of pancreatic cancer	9
Oncheong-eum alleviated hepatic lipid accumulation and intestinal barrier disruption in nonalcoholic steatohepatitis in vivo model	9
Regulation of PINK1/Parkin signaling pathway by berberine mediates mitochondrial autophagy to intervene in the proliferation and metastasis of thyroid cancer	8
Neuregulin-1 suppresses anti-apoptotic effect of Der p 38 on neutrophils by inhibition of cytokine secretion	8
NEAT1 promotes keratinocyte migration and proliferation during wound healing by regulating miR-26a-5p/LGR4 axis	8
RNA-binding protein SOX2 promotes distal metastasis and cisplatin resistance in non-small cell lung cancer by stabilizing CBLC	8
A novel immune-related LncRNA prognostic signature for cutaneous melanoma	8
Dihydrotanshinone I ameliorated angiotensin II-induced mitochondrial damage and oxidative stress in vascular smooth muscle cells	8
Concurrent upregulation of immune checkpoint molecule genes in colorectal cancer	8
ML385 suppresses the proliferation, migration, and invasion of thyroid carcinoma cells by impairing aerobic glycolysis	7

Nano-TiO2 removal using jellyfish extracts and an assessment of aquatic toxicity	7
Circ_0008351 acts as ceRNA for miR-942-5p to inhibit the progression of gastric cancer depending on the activation of PTGDR2	6
The therapeutic potential of Laggera alata in alleviating inflammation and oxidative stress: insights into the miR-150-5p/TRIM8 axis	6
Lung neoplasm development in a mouse model exposed to fine particulate matter in Korea	6
SQSTM1/p62 confers resistance of intrahepatic cholangiocarcinoma cells to 5-Fluorouracil by promoting Nrf2 nuclear translocation	6
DOS209 enhances metabolic protection: a randomized double-blind placebo-controlled trial	6
circLETM1 upregulates KRT80 via adsorbing miR-143-3p and promotes the progression of colorectal cancer	6
Disulfiram inhibits LPS-induced TLR4/NF-κB signaling in spheroids derived from human colorectal cancer cells	6
Correction to: Network analysis to understand side effects of UVB on skin through transcriptomic approach	5
Integrating RT-RPA/CRISPR system for the end-point visual detection of Mayaro virus	5
Illuminating the hepatotoxic mechanism of norcantharidin in rats using metabolomics analysis	5
Reduced cellular process and developmental process genotoxicity of polystyrene nanoplastics in zebrafish embryogenesis using Aurelia aurita proteins	5
A systematic review of the carcinogenicity of rats and mice by sex due to exposure to phenyl compounds	5
LncRNA PVT1 upregulates FBN1 by sponging miR-30b-5p to aggravate pulpitis	5
Angelica dahurica attenuates melanogenesis in B16F0 cells by repressing Wnt/β-catenin signaling	5
CTCF-mediated H3K27me3 enrichment on the LncRNA MALAT1 promoter regulates the cardiomyocytes from I/R-induced apoptosis through targeting miR-26b-5p	5
VCAN activates JAK/STAT signaling pathway to promote the progression of LPS-induced acute pneumonia	5
Protocatechuic acid alkyl ester derivatives alleviate TNF-α and LPS-induced inflammation in HaCaT cells	5
Protective role of S-carboxymethylcysteine against cyclophosphamide nephrotoxicity: involvement of Nrf2/HO-1 signaling and suppression of oxidative stress, inflammation, and apoptosis	5
Toxicogenomic analyses of ototoxic chemicals for workers’ health: a systematic review	4
Synergistic toxicity of endocrine disruptors and environmental toxicants under climate change	4
Stable expression of human Nav1.5 for high-throughput cardiac safety assessment	4
Flutriafol disrupts trophoblast function: mitochondrial dysfunction mediated cell cycle arrest and apoptosis	4
MiR-192-5p protects hexavalent chromium-induced apoptosis in renal epithelial cells by inhibiting p53 signaling pathway	4
Sodium hydroxide-induced Weissella kimchii ghosts (WKGs) as immunostimulant	4
MicroRNA-5582-3p alleviates the progression of osteosarcoma via targeting FZD4	4
MicroRNA-10a-5p targets SERPINE1 to suppress cell progression and epithelial–mesenchymal transition process in clear cell renal cell carcinoma	4
Scallop-derived plasmalogen attenuates amyloid beta-induced inflammation and apoptosis in SH-SY5Y cells	4
The effect of pesticides on the body of animals in the experiment	4
Mechanistic insight of mitochondrial dysfunctions in cardiovascular diseases with potential biomarkers	4
Efficacy of urinary trypsin inhibitor in the treatment of rats with severe sepsis and its effects on coagulation and immunity	4
Sublethal effects of acetaminophen exposure on benthic aquatic animal (Hydra magnipapillata)	4
Camellia sinensis (L.) mitigates copper oxide nanoparticles-induced lung inflammation and mucus production through suppressing MAPK signaling and MUC5AC	4
Circular RNA circ_0000877 serves as a miR-671-5p sponge to regulate diffuse large B-cell lymphoma development via HK2	4
KLF9 promotes autophagy and apoptosis in T-cell acute lymphoblastic leukemia cells by inhibiting AKT/mTOR signaling pathway	4
Benzo(a)pyrene-loaded gypsum dust-induced apoptosis of human bronchial epithelial cells through the Ahr signaling pathway	4
The effects of dantrolene and 2-aminoethoxydiphenyl borate (2-APB) on arsenic-induced osteoporosis	4
Transmembrane protein 106C accelerates the progression of breast cancer through the activation of PI3K/AKT/mTOR signaling	3
Circ_0000277 promotes the malignant progression of oesophageal squamous cell carcinoma through miR-1294-dependent regulation of DVL3	3
Premature ovarian insufficiency associated with environmental chemical exposure among Korean women: a study based on the Korean National Environmental Health Survey (2009–2012)	3
Aging and the effects of chronic intermittent hypoxia caused by obstructive sleep apnea	3
Screening of serum exosome markers for colorectal cancer based on Boruta and multi-cluster feature selection algorithms	3
Evaluation of the therapeutic efficacy of human skin equivalents manufactured through droplet-based bioprinting/nebulization technology	3
Single-cell transcriptomics to understand the cellular heterogeneity in toxicology	3
CARD9 regulates myocardial inflammation, oxidative stress, and vascular dysfunction in hypertensive rats by activating MAPK/p38 pathway in combination with NOD2	3
GSK621 ameliorates high glucose-induced renal injury by inducing autophagy via AMPK/ULK1 signaling pathway: an in vitro and in vivo study	3
Knockdown of lncRNA EGFR-AS1 promotes autophagy-mediated ferroptosis in cervical cancer via regulating EGFR expression through miR-133b	3
Icariin ameliorates chronic renal failure and fibrotic injury by modulating the STING signaling pathway to promote mitophagy	3
Myricetin alleviates pancreatic microcirculation and inflammation in rats with severe acute pancreatitis through FOXO1 and NF-κB pathways	3
Integrated analysis of miRNA and mRNA expression profiles in diabetic mouse kidney treated to Korean Red Ginseng	3

Physiological impacts of microplastics on the Pacific oyster Crassostrea gigas: The role of particle size and concentration	3
Ubiquitin ligase CHIP regulates neurological functional recovery after intracerebral hemorrhage through ubiquitination modification of FOXO1	3
Unveiling the impact of microplastics: a perspective on size, shape, and composition in human health	3
Influences of environmentally hazardous substances on atopic dermatitis: a review	3
Human exposure to micro- and nanoplastics: routes, accumulation, and health implications	3
Induction of glioblastoma invasion triggered by system Xc−-mediated glutamate release	3
Capparis spinosa inhibits proliferation and fibrosis of myofibroblasts in systemic sclerosis through modulation of MAPK signaling	3
Osthole protects against cartilage damage in knee osteoarthritis rats by attenuating inflammation and endoplasmic reticulum stress through the HMGB1/RAGE/NF-κB pathway	3
Chemically induced bacterial ghosts: a novel approach for advancing biomedical applications	3
The role of circSUCLG2 in mediating inflammatory response and bone remodeling imbalance in diabetic osteoporosis	3
HSP72 is a stimulus for activating toll-like receptor 2 in M2 macrophages leading to IL-6-mediated tumor malignancy	3
Coal dust exposure induces proliferation and migration of human bronchial epithelial cells	3
Valrubicin decreases cell proliferation in gastric cancer through the apoptosis induction	3
The mechanism of 5-aminolevulinic acid-photodynamic therapy pretreatment repressing keloid fibroblast proliferation and invasion by mediating forkhead box protein O6 (FoxO6) antioxidant stress	3
Anti-inflammatory activity of Akebia quinata D. extracts by inhibiting MAPK and NF-κB signaling pathways in LPS-induced RAW 264.7 cells according to extraction solvents	3
Salvia microphylla essential oil reduces cell viability in cisplatin-resistant clear cell type ovarian cancer cells caused by mitochondrial dysfunction	3
The efficacy of Plantago asiatica L. water extract on lipid metabolism in a high-fat diet-induced obese C57BL/6 mice	3
Sulfasalazine induces ferroptosis by regulating the PIAS3/JAK1/STAT3 pathway to prevent brain metastases of hepatocellular carcinoma	3
Up-regulation of PKCα and δ during beating cardiomyocyte differentiation of P19CL6 cells with suppressed apoptotic cell populations	3
Tolylfluanid induces developmental toxicity via liver dysfunction in zebrafish embryos	3
Salidroside attenuates myocardial fibrosis through hindering oxidative stress and inflammation via SIRT1/EZH2 signaling pathway	3
Fucoidan ameliorates amyloid-β 42 oligomer-induced neuronal apoptosis by activating the PI3K/Akt signaling pathway and MAPK cascades in human neuroblastoma SH-SY5Y cells	3
Correction: In vitro evaluation of new psychoactive substances (NPSs), 3,4-dichloromethylphenidate (DCMP), 4-EA-NBOMe, LY-2183240 and AB-CHFUPYCA	3
Bone marrow mesenchymal stem cell transplantation protects rats from myocardial infarction by regulating TXNIP/NLRP3 pathway-mediated inflammation and fibrosis	3
Decreased LTBP2 expression inhibits proliferation and migration of glioma	3
LINC00174 targeting miR-486-5p/EIF5A2 is an oncogenic driver in oral squamous cell carcinoma	3
Matrine promotes trophoblast invasion and reduces inflammation via miR-19a-3p to prevent preeclampsia	3