OOIR: Observatory of International Research

Papers

(The TQCC of Molecular & Cellular Toxicology is 2. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-04-01 to 2024-04-01.)

Article	Citations
Modifications of mRNA vaccine structural elements for improving mRNA stability and translation efficiency	71
Polystyrene microplastics induce mortality through acute cell stress and inhibition of cholinergic activity in a brine shrimp	46
Biochemical and physiological responses of the water flea Moina macrocopa to microplastics: a multigenerational study	21
Graviola leaves extract enhances the anticancer effect of cisplatin on various cancer cell lines	18
Ferulic acid exhibits anti-inflammatory effects by inducing autophagy and blocking NLRP3 inflammasome activation	18
The pine wood nematode Bursaphelenchus xylophilus and molecular diagnostic methods	16
Evaluation of cytotoxicity, genotoxicity, and zebrafish embryo toxicity of mixtures containing Hyssopus officinalis, Morus alba, Engraulis japonicus, and 27 other extracts for cosmetic safety assessme	13
Screening of cytotoxic and genotoxic potency of two pesticides (malathion and cypermethrin) on Allium cepa L.	12
Paclitaxel inhibits proliferation and promotes apoptosis through regulation ROS and endoplasmic reticulum stress in osteosarcoma cell	12
Antioxidant and apoptotic activity of cocoa bean husk extract on prostate cancer cells	10
The importance of multi-omics approaches for the health assessment of freshwater ecosystems	10
The first association study of single-nucleotide polymorphisms (SNPs) of the IFITM1 gene with influenza H1N1 2009 pandemic virus infection	9
Aqueous extract of Phragmites communis rhizomes attenuates phototoxicity in skin cells	9
Effect of combined therapy with camel milk-derived exosomes, tamoxifen, and hesperidin on breast cancer	9
Genetic association between the rs12252 SNP of the interferon-induced transmembrane protein gene and influenza A virus infection in the Korean population	9
Dual role of reactive oxygen species in autophagy and apoptosis induced by compound PN in prostate cancer cells	8
Cardiac biomarkers and detection methods for myocardial infarction	8
Effects of Agarum clathratum extract on cell death and calcium ion levels of ovarian cancer cell	8
Naringenin alleviates bone cancer pain in rats via down-regulating spinal P2X7R /PI3K/AKT signaling: involving suppression in spinal inflammation	7
Antigrowth effects of Kaempferia parviflora extract enriched in anthocyanidins on human ovarian cancer cells through Ca2+-ROS overload and mitochondrial dysfunction	7
Aptamer-linked immobilized sorbent assay for detecting GMO marker, phosphinothricin acetyltransferase (PAT)	7
Curcumin suppresses oxidative stress via regulation of ROS/NF-κB signaling pathway to protect retinal vascular endothelial cell in diabetic retinopathy	7
Dehydroabietic acid inhibits the gastric cancer cell growth via induced apoptosis and cell cycle arrest	7
Gum arabic-encapsulated gold nanoparticles modulate hypoxamiRs expression in tongue squamous cell carcinoma	7
Exposure to mercury induced early apoptotic signals in human placental BeWo cells through alteration of cell cycle regulation	6

Misoprostol alleviates paclitaxel-induced liver damage through its antioxidant and anti-apoptotic effects	6
Classification of dog skin diseases using deep learning with images captured from multispectral imaging device	6
Decreased plasma α-synuclein in idiopathic Parkinson’s disease patients after adjusting hemolysis factor	6
Acetaldehyde induces tau phosphorylation via activation of p38 MAPK/JNK and ROS production	6
Glycosidic flavonoids and their potential applications in cancer research: a review	6
Importance of GWAS in finding un-targeted genetic association of sporadic Alzheimer’s disease	6
Indole-6-carboxaldehyde prevents oxidative stress-induced mitochondrial dysfunction, DNA damage and apoptosis in C2C12 skeletal myoblasts by regulating the ROS-AMPK signaling pathway	5
Core fucosylation of maternal milk N-glycan prevents intestinal inflammation by regulating Treg/Th17 balance in infant gut microbiota	5
Hydrochloric acid-treated Bacillus subtilis ghosts induce IL-1 beta, IL-6, and TNF-alpha in murine macrophage	5
Application of the adverse outcome pathway framework to predict the toxicity of chemicals in the semiconductor manufacturing industry	5
Additional diagnostic testing of the 2019 novel coronavirus (SARS-CoV-2)	5
Physical and biomimetic treatment methods to reduce microplastic waste accumulation	5
Capture and toxicity assessment of Ag citrate nanoparticles using jellyfish extract	5
Transcriptome dynamics in benzo[a]pyrene exposed Hydra	4
Dapk1 promoted inflammation of infantile pneumonia by p38MAPK/NF-κB signaling pathway	4
Hosta longipes inhibits melanogenesis by reducing expression of the melanocortin 1 receptor	4
Madecassic acid protects human periodontal ligament fibroblasts against hydrogen peroxide-induced cell damage by maintaining mitochondrial membrane potential	4
Toxic effect of titanium dioxide nanoparticles on human mesenchymal stem cells	4
Sevoflurane induces neuronal apoptosis via enhancing DNMT3L expression and promoting methylation of PSD95 promoter in postoperative cognitive dysfunction	4
HS-1793 protects C2C12 cells from oxidative stress via mitochondrial function regulation	4
Screening of phytochemicals effective on relieving cancer cachexia in cisplatin-induced in vitro sarcopenia model	4
The neuroprotective effects of stimulation of NMDA receptors against POX-induced neurotoxicity in hippocampal cultured neurons; a morphometric study	4
Myricetin induces apoptosis mediated by oxidative stress in 4T1 and E0771 mammary cancer cells	4
Integrative comparison of cadmium and iron oxide as yellow pigment in terms of cellular stress and genotoxicity in vitro and in vivo	3
Methylparaben induces cell-cycle arrest and caspase-3-mediated apoptosis in human placental BeWo cells	3
Tissue-specific DNA damage response in Mouse Whole-body irradiation	3
miR-125-5p inhibits thyroid cancer growth and metastasis by suppressing the ERK/PI3K/AKT signal pathway	3
The optimal standard protocols for whole-genome sequencing of antibiotic-resistant pathogenic bacteria using third-generation sequencing platforms	3
Nrf2 suppresses erastin-induced ferroptosis through activating system Xc(-) in ovarian cancer	3
An integrated mRNA–microRNA regulatory network identified INHBA and has-miR-135a-5p as predictors of gastric cancer recurrence	3
The role of miRNA-155 in monocrotaline-induced pulmonary arterial hypertension through c-Fos/NLRP3/caspase-1	3
Autophagy inhibition contributes to epigallocatechin-3-gallate-mediated apoptosis in papillary thyroid cancer cells	3
Angelica dahurica attenuates melanogenesis in B16F0 cells by repressing Wnt/β-catenin signaling	3
Esculentoside A exerts anti-oxidative stress and anti-apoptotic effects in rat experimental membranous nephropathy by regulating MAPK pathway	3
Effects of α-mangostin on embryonic development and liver development in zebrafish	3
Down-regulation of PTTG1 suppresses PDGF-BB-induced proliferation, migration and extracellular matrix production of airway smooth muscle cells (ASMCs) by regulating PI3K/AKT/mTOR signaling pathway	3
Sample management: a primary critical starting point for successful omics studies	3
Prevention of acetaminophen-induced hepatocyte injury: JNK inhibition and GSTA1 involvement	3
The cytotoxic effects of bisphenol A alternatives in human lung fibroblast MRC5 cells	3
Wax-printed well pads and colorimetric LAMP detection of ApxIA toxin gene	3
Binding of silver nanowaste using jellyfish immune reaction extract and an assessment of aquatic toxicity	3
KLF5-trancripted miR-125b-5p is involved in enhancing the radio-sensitivity of breast cancer cells by targeting BRCA1	3
Anti-skin aging activity of eggshell membrane administration and its underlying mechanism	3
KIF11 inhibition decreases cytopathogenesis and replication of influenza A virus	3
N-type Cav channel inhibition by spider venom peptide of Argiope bruennichi	3
Curcumin promotes oxidative stress, apoptosis and autophagy in H9c2 rat cardiomyoblasts	3
Combined treatment of ginsenoside Rg2 and piceatannol mixture reduces the apoptosis and DNA damage induced by UVB in HaCaT cells	3
Oleuropein induces apoptosis in colorectal tumor spheres via mitochondrial fission	3
Isofraxidin exerts anti-diabetic, antilipidemic, and antioxidant effects and protects renal tissues via inhibition of NF-ĸB in Streptozotocin-induced diabetic rats	3
microRNA-184 enhances the sensitivity of pheochromocytoma-12 cells to doxorubicin by targeting ADAM22	2

Sodium aescinate alleviates bone cancer pain in rats by suppressing microglial activation via p38 MAPK/c-Fos signaling	2
Kaempferol attenuates spinal cord injury by interfering inflammatory and oxidative stress by targeting the p53 protein: a molecular docking analysis	2
Extracellular polysaccharides purified (Polycan) from Aureobasidium pullulans SM‑2001 improves pathophysiology of dystrophin-deficient mdx mice	2
Liver kinase B1 (LKB1) reduced inflammation and oxidative stress by regulating the AMPK/NLRP3 signaling pathway in LPS-induced lung injury	2
Network analysis to understand side effects of UVB on skin through transcriptomic approach	2
Trichloroethylene injures rat liver and elevates the level of peroxisomal bifunctional enzyme (Ehhadh)	2
Mitochondrial dysfunction is underlying fluoroquinolone toxicity: an integrated mitochondrial toxicity assessment	2
In vitro evaluation of antioxidant activity and biocompatibility of caffeic acid phenethyl ester loaded in polymeric micelles	2
S-ketamine promotes autophagy and alleviates neuropathic pain by inhibiting PI3K/Akt/mTOR signaling pathway	2
FXYD3 promotes the proliferation, migration, and invasion of pancreatic cancer cells by regulating the cGMP-PKG signaling pathway	2
Therapeutic potential of snake venom, l-amino oxidase and sorafenib in hepatocellular carcinoma	2
Occupational exposure to mixtures and toxic pathways prediction for workers’ health	2
Correction to: Network analysis to understand side effects of UVB on skin through transcriptomic approach	2
Pirfenidone ameliorated AGE-induced EMT and attenuated peritoneal fibrosis in peritoneal mesothelial cells	2
Blockade of stromal cell-derived factor-1 signaling disturbs the invasiveness of human extravillous trophoblast cells	2
CTCF-mediated H3K27me3 enrichment on the LncRNA MALAT1 promoter regulates the cardiomyocytes from I/R-induced apoptosis through targeting miR-26b-5p	2
miR-29 family inhibited the proliferation and migration of lung cancer cells by targeting SREBP-1	2
Anti-proliferation and pro-apoptosis effects of miR-582-5p in chronic lymphocytic leukemia via targeting HNRNPA1 and suppression of NF-κB	2
Transcriptional responses in Ecklonia cava to short-term exposure to polycyclic aromatic hydrocarbons	2
Pulmonary inflammation caused by silica dioxide nanoparticles in mice via TXNIP/NLRP3 signaling pathway	2
S-Adenosylmethionine enhances the inhibitory effect of gemcitabine against pancreatic cancer cells via suppression of the EGFR/AKT pathways	2
Classification of advanced methods for evaluating neurotoxicity	2
MiR-193b enhanced proliferation and migration and inhibits apoptosis through targeting RAB7A in osteosarcoma cell	2
Lipopolysaccharide alters VEGF-A secretion of mesenchymal stem cells via the integrin β3-PI3K-AKT pathway	2
Comparison of the cytotoxicity of bisphenol A and its analogs on human placental BeWo cells	2
Momordica charantia extracts obtained by ultrasound-assisted extraction inhibit the inflammatory pathways	2
Subcutaneous toxicity of melittin-dKLA in ICR mice	2
Comparative toxicity of polyhexamethylene guanidine phosphate in three strains of rats	2