Tissue Engineering and Regenerative Medicine

Article	Citations
Therapeutic Effect of IL1β Priming Tonsil Derived-Mesenchymal Stem Cells in Osteoporosis	127
Reduction of Low-Density Lipoprotein Cholesterol by Mesenchymal Stem Cells in a Mouse Model of Exogenous Cushing’s Syndrome	69
Intra-Articular Injection of miR-29a-3p of BMSCs Promotes Cartilage Self-Repairing and Alleviates Pain in the Rat Osteoarthritis	52
Acoustic and Magnetic Stimuli-Based Three-Dimensional Cell Culture Platform for Tissue Engineering	51
α-Gal Nanoparticles in CNS Trauma: II. Immunomodulation Following Spinal Cord Injury (SCI) Improves Functional Outcomes	50
IL-33 Promotes ST2-Dependent Fibroblast Maturation via P38 and TGF-β in a Mouse Model of Epidural Fibrosis	49
A Novel Hypothesis and Characterization to Isolate Microvascular Endothelial Cells Simultaneously with Adipose-Derived Stem Cells from the Human Adipose-Derived Stromal Vascular Fraction	46
The Osteogenic Role of Biomaterials Combined with Human-Derived Dental Stem Cells in Bone Tissue Regeneration	38
Deep Learning Model for Predicting Airway Organoid Differentiation	32
The Biocompatibility of Multi-Source Stem Cells and Gelatin-Carboxymethyl Chitosan-Sodium Alginate Hybrid Biomaterials	30
Using Pre-Clinical Studies to Explore the Potential Clinical Uses of Exosomes Secreted from Induced Pluripotent Stem Cell-Derived Mesenchymal Stem cells	30
Asymmetric Contribution of Blastomere Lineages of First Division of the Zygote to Entire Human Body Using Post-Zygotic Variants	30
Multiple Injections of Adipose-Derived Stem Cells Improve Graft Survival in Human-to-Rat Skin Xenotransplantation through Immune Modulation	26
Isolation of High Purity Mouse Mesenchymal Stem Cells through Depleting Macrophages Using Liposomal Clodronate	26
Current Modalities for Fracture Healing Enhancement	25
Mesenchymal Stem Cell Transplantation for Ischemic Diseases: Mechanisms and Challenges	23
Fat Graft with Allograft Adipose Matrix and Magnesium Hydroxide-Incorporated PLGA Microspheres for Effective Soft Tissue Reconstruction	22
Development of a Novel Perfusion Rotating Wall Vessel Bioreactor with Ultrasound Stimulation for Mass-Production of Mineralized Tissue Constructs	22
Human Fetal Cartilage-Derived Progenitor Cells Exhibit Anti-Inflammatory Effect on IL-1β-Mediated Osteoarthritis Phenotypes In Vitro	22
Mucosal Vaccine Delivery Using Mucoadhesive Polymer Particulate Systems	22
Efficacy and Safety Evaluation of Tacrolimus-Eluting Stent in a Porcine Coronary Artery Model	21
Motion-Accommodating Dual-Layer Hydrogel Dressing to Deliver Adipose-Derived Stem Cells to Wounds	21
Vessel-Derived Decellularized Extracellular Matrices (VdECM): Novel Bio-Engineered Materials for the Wound Healing	18
Heparin Immobilization of Tissue Engineered Xenogeneic Small Diameter Arterial Scaffold Improve Endothelialization	18
MiRNA320a Inhibitor-Loaded PLGA-PLL-PEG Nanoparticles Contribute to Bone Regeneration in Trauma-Induced Osteonecrosis Model of the Femoral Head	16

pH/Temperature Responsive Curcumin-Loaded Micelle Nanoparticles Promote Functional Repair after Spinal Cord Injury in Rats via Modulation of Inflammation	16
Extracellular Vesicles Carrying RUNX3 Promote Differentiation of Dental Pulp Stem Cells	16
Extracorporeal Shock Wave Combined with Teriparatide-Loaded Hydrogel Injection Promotes Segmental Bone Defects Healing in Osteoporosis	15
Platelet-Derived Growth Factor-BB Priming Enhances Vasculogenic Capacity of Bone Marrow-Derived Endothelial Precursor Like Cells	15
rhBMP-2-Conjugated Three-Dimensional-Printed Poly(l-lactide) Scaffold is an Effective Bone Substitute	15
Unlocking the Potential of Extracellular Vesicles as the Next Generation Therapy: Challenges and Opportunities	14
Hypoxic Stress Induces Complement-Mediated Lysis of Mesenchymal Stem Cells by Downregulating Factor H and CD59	14
The Concept of Early Osteoarthritis and Its Significance in Regenerative Medicine	14
Modulation of 3D Bioprintability in Polysaccharide Bioink by Bioglass Nanoparticles and Multiple Metal Ions for Tissue Engineering	14
Immunomodulation for Tissue Repair and Regeneration	13
Chitosan Nerve Grafts Incorporated with SKP-SC-EVs Induce Peripheral Nerve Regeneration	13
Tissue Engineering and Regenerative Medicine in the Field of Otorhinolaryngology	13
Acellular Scaffolds as Innovative Biomaterial Platforms for the Management of Diabetic Wounds	13
Immunomodulation Effects of Porcine Cartilage Acellularized Matrix (pCAM) for Osteoarthritis Treatment	13
Multifunctional Microneedle Patch with Diphlorethohydroxycarmalol for Potential Wound Dressing	13
A Comparative Study of an Anti-Thrombotic Small-Diameter Vascular Graft with Commercially Available e-PTFE Graft in a Porcine Carotid Model	13
The Application of L-Serine-Incorporated Gelatin Sponge into the Calvarial Defect of the Ovariectomized Rats	13
Atorvastatin Pretreatment Ameliorates Mesenchymal Stem Cell Migration through miR-146a/CXCR4 Signaling	12
Transplantation of PSA-NCAM-Positive Neural Precursors from Human Embryonic Stem Cells Promotes Functional Recovery in an Animal Model of Spinal Cord Injury	12
Optimizing Decellularization Strategies for the Efficient Production of Whole Rat Kidney Scaffolds	12
Macrophage Polarization: A Novel Target and Strategy for Pathological Scarring	12
Mesenchymal Stem Cell-Derived Extracellular Vesicles Carrying Circ-Tulp4 Attenuate Diabetes Mellitus with Nonalcoholic Fatty Liver Disease by Inhibiting Cell Pyroptosis through the HNRNPC/ABHD6 Axis	11
Surface Creasing-Induced Micropatterned GelMA Using Heating-Hydration Fabrication for Effective Vascularization	11
Demineralized Dentin Matrix for Dental and Alveolar Bone Tissues Regeneration: An Innovative Scope Review	11
The Therapeutic Effects of Exosomes Derived from Human Umbilical Cord Mesenchymal Stem Cells on Scleroderma	10
Engineering of Cell Derived-Nanovesicle as an Alternative to Exosome Therapy	10
Bone Regeneration with 3D-Printed Hybrid Bone Scaffolds in a Canine Radial Bone Defect Model	10
Silicate Ions Derived from Calcium Silicate Extract Decelerate Ang II-Induced Cardiac Remodeling	10
Tissue Engineered Mini-Cornea Model for Eye Irritation Test	10
Long and Short-Term Effect of mTOR Regulation on Cerebral Organoid Growth and Differentiations	10
A Comprehensive Cancer-Associated MicroRNA Expression Profiling and Proteomic Analysis of Human Umbilical Cord Mesenchymal Stem Cell-Derived Exosomes	10
Graded-Three-Dimensional Cell-Encapsulating Hydrogel as a Potential Biologic Scaffold for Disc Tissue Engineering	10
Effect of TNF-α and IL-6 on Compact Bone-Derived Cells	10
AuNP-Loaded Electrospinning Membrane Cooperated with CDs for Periodontal Tissue Engineering	10
Exosomes Derived from Rejuvenated Stem Cells Inactivate NLRP3 Inflammasome and Pyroptosis of Nucleus Pulposus Cells via the Transfer of Antioxidants	10
Mesenchymal Stem Cell Secreted-Extracellular Vesicles are Involved in Chondrocyte Production and Reduce Adipogenesis during Stem Cell Differentiation	10
Effects of Cetrorelix on Ovary and Endometrium Prior to Anti-PD-L1 Antibody in Murine Model	9
CA1 Modulates the Osteogenic Differentiation of Dental Follicle Stem Cells by Activating the BMP Signaling Pathway In Vitro	9
Generation of Connective Tissue-Free Microvascular Fragment Isolates from Subcutaneous Fat Tissue of Obese Mice	9
Advanced In Vitro Three-Dimensional Skin Models of Atopic Dermatitis	9
Adipose Tissue-Derived Mesenchymal Stem Cell Inhibits Osteoclast Differentiation through Tumor Necrosis Factor Stimulated Gene-6	9
Fabricating Composite Cell Sheets for Wound Healing: Cell Sheets Based on the Communication Between BMSCs and HFSCs Facilitate Full-Thickness Cutaneous Wound Healing	9
Therapeutic Effect of HDAC5 Binding and Cell Penetrating Peptide for the Treatment of Inflammatory Bowel Disease	9
Define of Optimal Addition Period of Osteogenic Peptide to Accelerate the Osteogenic Differentiation of Human Pluripotent Stem Cells	9
Intestinal Peyer’s Patches: Structure, Function, and In Vitro Modeling	9
Bone Morphogenic Protein-2-Conjugated Three-Dimensional-Printed Poly (L-Lactic Acid) (PLLA) Scaffold is likely Promising as an Effective Bone Substitute	9
Protection of the Vascular System by Polyethylene Glycol Reduces Secondary Injury Following Spinal Cord Injury in Rats	8
LGR5 Modulates Differentiated Phenotypes of Chondrocytes Through PI3K/AKT Signaling Pathway	8
M2 Macrophage-Derived Concentrated Conditioned Media Significantly Improves Skin Wound Healing	8
Establishment of an In Vitro Embryo-Endometrium Model Using Alginate-Embedded Mouse Embryos and Human Embryoid Body	8

Gingival Mesenchymal Stem Cells: A Periodontal Regenerative Substitute	8
Reducing Nogo-B Improves Hepatic Fibrosis by Inhibiting BACe1-Mediated Autophagy	8
circ_SPEF2 Regulates the Balance of Treg Cells by Regulating miR-16-5p/BACH2 in Lymphoma and Participates in the Immune Response	8
Implantation of Bone Marrow Mesenchymal Stem Cells into Small Intestinal Submucosa Improves Bile Duct Injury in Rabbits	8
Relationship between Tissue Regeneration and Immune Modulation	8
Lung Organoids: Systematic Review of Recent Advancements and its Future Perspectives	8
Regenerative Functions of Regulatory T Cells and Current Strategies Utilizing Mesenchymal Stem Cells in Immunomodulatory Tissue Regeneration	8
Unlocking Therapeutic Potential: Camphorquinone’s Role in Alleviating Non-Alcoholic Fatty Liver Disease via SIRT1/LKB1/AMPK Pathway Activation	8
Regenerative Strategies in Treatment of Peripheral Nerve Injuries in Different Animal Models	8
Kartogenin Promotes the BMSCs Chondrogenic Differentiation in Osteoarthritis by Down-Regulation of miR-145-5p Targeting Smad4 Pathway	7
Exosomes Derived from Mouse Breast Carcinoma Cells Facilitate Diabetic Wound Healing	7
Fabrication and Characterization of Graphene Oxide-Coated Plate for Efficient Culture of Stem Cells	7
Three-Dimensional Bioprinting Scaffolding for Nasal Cartilage Defects: A Systematic Review	7
Decellularized Human Adipose Tissue as an Alternative Graft Material for Bone Regeneration	7
Cyclic Stretching Induces Maturation of Human-Induced Pluripotent Stem Cell-Derived Cardiomyocytes through Nuclear-Mechanotransduction	7
Selective Serotonin Reuptake Inhibitor Promotes Bone-Tendon Interface Healing in a Rotator Cuff Tear Rat Model	7
Electrospinning Fabrication Methods to Incorporate Laminin in Polycaprolactone for Kidney Tissue Engineering	7
Exosomal microRNAs from Mesenchymal Stem Cells: Novel Therapeutic Effect in Wound Healing	7
Comparison of Autogenous Tooth Materials and Other Bone Grafts	7
Cross-Linking Methods of the Silk Protein Hydrogel in Oral and Craniomaxillofacial Tissue Regeneration	7
Proliferation-Related Features of the Human Mesenchymal Stem Cells Derived from Palatine Tonsils, Adipose Tissues, and Bone Marrow	7
Matrix Metalloproteinase 1 as a Marker of Tonsil-Derived Mesenchymal Stem Cells to Assess Bone Marrow Cell Migration	7
Cassia Angustifolia Primed ASCs Accelerate Burn Wound Healing by Modulation of Inflammatory Response	7
Generation of Hepatic Progenitor Cells from the Primary Hepatocytes of Nonhuman Primates Using Small Molecules	6
Tissue-Engineered Hydroxyapatite Bone Scaffold Impregnated with Osteoprogenitor Cells Promotes Bone Regeneration in Sheep Model	6
Advancements in Human Embryonic Stem Cell Research: Clinical Applications and Ethical Issues	6
Correction to: Polydeoxyribonucleotide and Polynucleotide Improve Tendon Healing and Decrease Fatty Degeneration in a Rat Cuff Repair Model	6
Exosomes-Shuttled lncRNA SNHG7 by Bone Marrow Mesenchymal Stem Cells Alleviates Osteoarthritis Through Targeting miR-485-5p/FSP1 Axis-Mediated Chondrocytes Ferroptosis and Inflammation	6
The Intrinsic Relation between the Hydrogel Structure and In Vivo Performance of Hyaluronic Acid Dermal Fillers: A Comparative Study of Four Typical Dermal Fillers	6
Effectiveness of Mesenchymal Stem Cell Secretome on Wound Healing: A Systematic Review and Meta-analysis	6
Development of an In Vitro Model for Inflammation Mediated Renal Toxicity Using 3D Renal Tubules and Co-Cultured Human Immune Cells	6
Biodistribution of Exosomes and Engineering Strategies for Targeted Delivery of Therapeutic Exosomes	6
Correction to: Hsp20 Promotes Endothelial Progenitor Cell Angiogenesis via Activation of PI3K/Akt Signaling Pathway Under Hypoxia	6
Effects of Late-Passage Small Umbilical Cord–Derived Fast Proliferating Cells on Tenocytes from Degenerative Rotator Cuff Tears under an Interleukin 1β-Induced Tendinopathic Environment	6
Engineering of Extracellular Vesicles Based on Payload Changes for Tissue Regeneration	6
Development of Matrix Metalloproteinases-Mediated Extracellular Matrix Remodeling in Regenerative Medicine: A Mini Review	6
Remodeling and Restraining Lung Tissue Damage Through the Regulation of Respiratory Immune Responses	6
Correction to: Three-Dimensional Cell Culture System for Tendon Tissue Engineering	6
Liver Organoids: Formation Strategies and Biomedical Applications	6
Correction to: Biomimetic Biphasic Electrospun Scaffold for Anterior Cruciate Ligament Tissue Engineering	6
Reconstructed Human Skin with Hypodermis Shows Essential Role of Adipose Tissue in Skin Metabolism	5
Human Endometrium Derived Induced Pluripotent Stem Cells Are Amenable to Directed Erythroid Differentiation	5
Extraction and Characterization of Human Adipose Tissue-Derived Collagen: Toward Xeno-Free Tissue Engineering	5
Improvement of IgA Nephropathy and Kidney Regeneration by Functionalized Hyaluronic Acid and Gelatin Hydrogel	5
Synergistic Effect of Whitlockite Scaffolds Combined with Alendronate to Promote Bone Regeneration	5
Role of Klotho and N-acetylcysteine in Oxidative Stress Associated with the Vitrification of Ovarian Tissue Cytoprotective Function of Klotho in Cryopreservation	5
Bulk Modification with Inorganic Particles and Immobilization of Extracellular Vesicles onto PDO Composite for Facial Rejuvenation	5
Injectable and Cell-Laden Hydrogel in the Contained Bone Defect Animal Model: A Systematic Review	5
Towards Full Thickness Small Intestinal Models: Incorporation of Stromal Cells	5
Pathological Characteristics of Monosodium Iodoacetate-Induced Osteoarthritis in Rats	5
Schisandrin B Improves the Hypothermic Preservation of Celsior Solution in Human Umbilical Cord Mesenchymal Stem Cells	5
The Neuropeptide Spexin Promotes the Osteoblast Differentiation of MC3T3-E1 Cells via the MEK/ERK Pathway and Bone Regeneration in a Mouse Calvarial Defect Model	5
Comparison of the Angiogenic Ability between SHED and DPSC in a Mice Model with Critical Limb Ischemic	5
Stabilization of Lipid Lamellar Bilayer Structure of Stratum Corneum Modulated by Poly (2-methacryloyloxyethyl phosphorylcholine) in Relation to Skin Hydration and Skin Protection	5
Reduced Cell Migration in Human Chondrocyte Sheets Increases Tissue Stiffness and Cartilage Protein Production	5
The Role of Low-Frequency Electromagnetic Fields on Mesenchymal Stem Cells Differentiation: A Systematic Review	5
Laser-Structured Si and PLGA Inhibit the Neuro2a Differentiation in Mono- and Co-Culture with Glia	5
Near-infrared Transillumination and Photodynamic Therapy Using Hypericin in Animal Laryngeal Tumors	5
Enhancing Skin Regeneration Efficacy of Human Dermal Fibroblasts Using Carboxymethyl Cellulose-Coated Biodegradable Polymer	5
Glycinamide Facilitates Nanocomplex Formation and Functions Synergistically with Bone Morphogenetic Protein 2 to Promote Osteoblast Differentiation In Vitro and Bone Regeneration in a Mouse Calvarial	5
Exploring the Cocktail Factor Approach to Generate Salivary Gland Progenitors through Co-Culture Techniques	5
High-Speed Clearing and High-Resolution Staining for Analysis of Various Markers for Neurons and Vessels	5
Growth and Differentiation of Circulating Stem Cells After Extensive Ex Vivo Expansion	5
Adipose-Derived Mesenchymal Stem Cells and Their Derived Epidermal Progenitor Cells Conditioned Media Ameliorate Skin Aging in Rats	4
An Organotypic Human Lymph Node Model Reveals the Importance of Fibroblastic Reticular Cells for Dendritic Cell Function	4
Enhancement of Immune Responses Elicited by Nanovaccines through a Cross-Presentation Pathway	4
Application of Cartilage Extracellular Matrix to Enhance Therapeutic Efficacy of Methotrexate	4
Three Dimensional Bioprinting for Hepatic Tissue Engineering: From In Vitro Models to Clinical Applications	4
TGFβ1-Induced Transglutaminase-2 Triggers Catabolic Response in Osteoarthritic Chondrocytes by Modulating MMP-13	4
Validation of the Osteomyelitis Induced by Methicillin-Resistant Staphylococcus aureus (MRSA) on Rat Model with Calvaria Defect	4
Use of Human Gingival Fibroblasts for Pre-Vascularization Strategies in Oral Tissue Engineering	4
Intra-Articular Atelocollagen Injection for the Treatment of Articular Cartilage Defects in Rabbit Model	4
Atelocollagen Scaffold Enhances Cartilage Regeneration in Osteochondral Defects: A Study in Rabbits	4
Breast Tissue Reconstruction Using Polycaprolactone Ball Scaffolds in a Partial Mastectomy Pig Model	4
Bioactive Bone Substitute in a Rabbit Ulna Model: Preclinical Study	4
Modulation of Inflammatory Responses to Enhance Nerve Recovery after Spinal Cord Injury	4
Biomimetic Biphasic Electrospun Scaffold for Anterior Cruciate Ligament Tissue Engineering	4
Correction to: TGFβ1-Induced Transglutaminase-2 Triggers Catabolic Response in Osteoarthritic Chondrocytes by Modulating MMP-13	4
Polydeoxyribonucleotide and Polynucleotide Improve Tendon Healing and Decrease Fatty Degeneration in a Rat Cuff Repair Model	4
Comparison of Biological Characteristics of Human Umbilical Cord Wharton’s Jelly-Derived Mesenchymal Stem Cells from Extremely Preterm and Term Infants	4

Hyaluronic Acid Based Adipose Tissue-Derived Extracellular Matrix Scaffold in Wound Healing: Histological and Immunohistochemical Study	4
Combining Diced Cartilage with Chondrocyte Spheroids in GelMA Hydrogel: An Animal Study in Diced Cartilage Grafting Technique	4
Comparative Study of Two Common In Vitro Models for the Pancreatic Islet with MIN6	4
Thermosensitive Hydrogel Loaded with Primary Chondrocyte-Derived Exosomes Promotes Cartilage Repair by Regulating Macrophage Polarization in Osteoarthritis	4
An Insight of Nanomaterials in Tissue Engineering from Fabrication to Applications	4
Effect of Urolithin A on Bone Repair in Mice with Bone Defects	4
Signal Transducer and Activator of Transcription 4-Induced Up-Regulated LINC01278 Enhances Proliferation and Invasion of Non-Small Cell Lung Cancer Cells via the MicroRNA-877-5p/Activating Transcripti	4
In Situ-Forming Collagen/poly-γ-glutamic Acid Hydrogel System with Mesenchymal Stem Cells and Bone Morphogenetic Protein-2 for Bone Tissue Regeneration in a Mouse Calvarial Bone Defect Model	4
Minimal Cube Explant Provides Optimal Isolation Condition of Mesenchymal Stem Cells from Umbilical Cord	4
Preparation and In Vitro Characterization of Gelatin Methacrylate for Corneal Tissue Engineering	3
Mesenchymal Stem Cell-Derived Extracellular Vesicles in the Management of COVID19-Associated Lung Injury: A Review on Publications, Clinical Trials and Patent Landscape	3
Comparison of the Infant and Adult Adipose-Derived Mesenchymal Stem Cells in Proliferation, Senescence, Anti-oxidative Ability and Differentiation Potential	3
Engineered Extracellular Vesicles as a Targeted Delivery Platform for Precision Therapy	3
PLGA Microspheres Containing Hydrophobically Modified Magnesium Hydroxide Particles for Acid Neutralization-Mediated Anti-Inflammation	3
Exosomes and Exosome-Mimetics for Atopic Dermatitis Therapy	3
IL-10 Deficiency Aggravates Renal Inflammation, Fibrosis and Functional Failure in High-Fat Dieted Obese Mice	3
Nanoparticle-Based Chimeric Antigen Receptor Therapy for Cancer Immunotherapy	3
Adipose-Derived Stem Cell Exosomes Promoted Hair Regeneration	3
Delivery of SAV-siRNA via Exosomes from Adipose-Derived Stem Cells for the Treatment of Myocardial Infarction	3
The Progress of Stem Cell Therapy in Myocardial-Infarcted Heart Regeneration: Cell Sheet Technology	3
Restoration of Immune Privilege in Human Dermal Papillae Controlling Epithelial-Mesenchymal Interactions in Hair Formation	3
Enhancing Cardiomyocyte Purity through Lactate-Based Metabolic Selection	3
Bone Marrow Aspiration Concentrate in the Treatment of Osteoarthritis: A Review of its Current Clinical Application	3
Three-Dimensional Modeling of the Structural Microenvironment in Post-Traumatic War Wounds	3
The Therapeutic Potential of Amniotic Fluid-Derived Stem Cells on Busulfan-Induced Azoospermia in Adult Rats	3
The Combination of Platelet Rich Plasma Gel, Human Umbilical Mesenchymal Stem Cells and Nanohydroxyapatite/polyamide 66 Promotes Angiogenesis and Bone Regeneration in Large Bone Defect	3
Photobiomodulation Facilitates Rat Cutaneous Wound Healing by Promoting Epidermal Stem Cells and Hair Follicle Stem Cells Proliferation	3
Development and Application of Three-Dimensional Bioprinting Scaffold in the Repair of Spinal Cord Injury	3
Lipid Priming of Adipose Mesenchymal Stromal Cells with Docosahexaenoic Acid: Impact on Cell Differentiation, Senescence and the Secretome Neuroregulatory Profile	3