Pharmacological Reports

Article	Citations
Guanfacine inhibits interictal epileptiform events and sodium currents in prefrontal cortex pyramidal neurons	72
Advanced pharmacological and pharmacokinetic evaluation of 1,3 dimethylpurine-2,6-dione derivative (GR-14) with prominent mood-modulating activity in rats	66
ONC206, an imipridone derivative, demonstrates anti-colorectal cancer activity against stem/progenitor cells in 3D cell cultures and in patient-derived organoids	66
Effects of puerarin on gait disturbance in a 6-hydroxydopamine mouse model of Parkinson’s disease	49
Targeting GABA signaling in type 1 diabetes and its complications- an update on the state of the art	47
The KCNQ channel inhibitor XE991 suppresses nicotinic acetylcholine receptor-mediated responses in rat intracardiac ganglion neurons	46
Use of glucocorticoids and azithromycin in the therapy of COVID-19	45
GLUT inhibitor WZB117 induces cytotoxicity with increased production of amyloid-beta peptide in SH-SY5Y cells preventable by beta-hydroxybutyrate: implications in Alzheimer’s disease	45
Synthetic lipoproteins based on apolipoprotein E coupled to fullerenol have anti-atherosclerotic properties	42
Chloroquine prevents hypoxic accumulation of HIF-1α by inhibiting ATR kinase: implication in chloroquine-mediated chemosensitization of colon carcinoma cells under hypoxia	37
Evaluating human epidermal growth factor receptor 2 roles in the efficacy of Tamoxifen treatment in breast cancer, a systematic review	37
CYX-5, a G-protein biassed MOP receptor agonist, DOP receptor antagonist and KOP receptor agonist, evokes constipation but not respiratory depression relative to morphine in rats	36
Mitragynine inhibits hippocampus neuroplasticity and its molecular mechanism	36
Atypical antipsychotic olanzapine inhibits voltage-dependent K+ channels in coronary arterial smooth muscle cells	35
FNF-12, a novel benzylidene-chromanone derivative, attenuates inflammatory response in in vitro and in vivo asthma models mediated by M2-related Th2 cytokines via MAPK and NF-kB signaling	35
In vitro antiviral activity of piperidine alkaloids from Senna spectabilis flowers on Chikungunya virus infection	34
Network analysis of monoamines involved in anxiety-like behavior in a rat model of osteoarthritis	30
Hypoxia-inducible factors and essential hypertension: narrative review of experimental and clinical data	30
Evaluation of a warfarin dosing algorithm including CYP2C9, VKORC1, and CYP4F2 polymorphisms and non-genetic determinants for the Iranian population	27
Antiviral activity of some benzo[g]quinazolines against coxsackievirus B4: biological screening and docking study	26
Impact of SARS CoV-2 /COVID-19 infection on the course of advanced chronic liver disease and hepatocellular carcinoma	26
Role of the β2-adrenergic receptor in podocyte injury and recovery	25
The impact of excessive maternal weight on the risk of neuropsychiatric disorders in offspring—a narrative review of clinical studies	25
Mediator kinase module proteins, genetic alterations and expression of super-enhancer regulated genes in colorectal cancer	23
Redox homeostasis in human renal cells that had been treated with amphotericin B in combination with selected 1,3,4-thiadiazole derivatives	23

Challenges of current treatment and exploring the future prospects of nanoformulations for treatment of atopic dermatitis	22
Acknowledgments	22
Effect of heme oxygenase-1 on the differentiation of human myoblasts and the regeneration of murine skeletal muscles after acute and chronic injury	22
Alpha-lipoic acid, apocynin or probiotics influence glutathione status and selected inflammatory parameters in C57/BL6 mice when combined with a low-fat diet	21
Chlorogenic acid reduces inflammation in murine model of acute pancreatitis	21
Safety of non-standard regimen of systemic steroid therapy in patients with Graves’ orbitopathy: a single-centre experience	20
The association between the use of ivermectin and mortality in patients with COVID-19: a meta-analysis	19
Migraine and the microbiota. Can probiotics be beneficial in its prevention? - a narrative review	19
MDPV (3,4-methylenedioxypyrovalerone) administered to mice during development of the central nervous system produces persistent learning and memory impairments	19
Antiproliferative pharmacophore azo-hydrazone analogue BT-1F exerts death signalling pathway targeting STAT3 in solid tumour	19
Exposure to chronic stressor upsurges the excitability of serotoninergic neurons and diminishes concentrations of circulating corticosteroids in rats two weeks thereafter	19
Allosteric modulation of dopamine D2L receptor in complex with Gi1 and Gi2 proteins: the effect of subtle structural and stereochemical ligand modifications	19
Transient plasticity response is regulated by histone deacetylase inhibitor in oxygen–glucose deprivation condition	18
Cannabinoids in the treatment of glioblastoma	18
Colonic inflammation induces changes in glucose levels through modulation of incretin system	18
GET73 modulates lipopolysaccharide- and ethanol-induced increase in cytokine/chemokine levels in primary cultures of microglia of rat cerebral cortex	17
The influence of preconditioning with low dose of LPS on paraquat-induced neurotoxicity, microglia activation and expression of α-synuclein and synphilin-1 in the dopaminergic system	17
Research progress of propofol in alleviating cerebral ischemia/reperfusion injury	17
Nanoparticles coated by chloramphenicol in hydrogels as a useful tool to increase the antibiotic release and antibacterial activity in dermal drug delivery	17
Shedding light on the role of CX3CR1 in the pathogenesis of schizophrenia	16
Amphetamine-induced prolonged disturbances in tissue levels of dopamine and serotonin in the rat brain	16
Luteolin for neurodegenerative diseases: a review	16
In vitro biological evaluation of a novel folic acid-targeted receptor quantum dot−β−cyclodextrin carrier for C−2028 unsymmetrical bisacridine in the treatment of human lung and prostate cancers	15
Unraveling the mechanistic interplay of mediators orchestrating the neuroprotective potential of harmine	15
Potential drugs for the treatment of Alzheimer’s disease	15
Advances in the anti-tumor mechanisms of saikosaponin D	15
A derivative of 3-(1,3-diarylallylidene)oxindoles inhibits dextran sulfate sodium-induced colitis in mice	15
Interactions of antidepressants with concomitant medications—safety of complex therapies in multimorbidities	15
Can probiotics be used in the prevention and treatment of bronchial asthma?	15
Nanoformulation of dasatinib cannot overcome therapy resistance of pancreatic cancer cells with low LYN kinase expression	14
Molecular pattern of a decrease in the rewarding effect of cocaine after an escalating-dose drug regimen	14
Presynaptic antiseizure medications - basic mechanisms and clues for their rational combinations	14
A re-consideration of neural/receptor mechanisms in chemotherapy-induced nausea and vomiting: current scenario and future perspective	14
Is metformin neuroprotective against diabetes mellitus-induced neurodegeneration? An updated graphical review of molecular basis	13
The protective effects of statins in traumatic brain injury	13
Simultaneous determination of four antibiotics in human urine and hair samples employing a simple and efficient dispersive micro solid-phase extraction-high performance liquid chromatography	12
Tanshinone IIA targeting cell signaling pathways: a plausible paradigm for cancer therapy	12
Therapeutic implications of phosphorylation- and dephosphorylation-dependent factors of cAMP-response element-binding protein (CREB) in neurodegeneration	12
Therapeutic drug monitoring of mycophenolic acid (MPA) using volumetric absorptive microsampling (VAMS) in pediatric renal transplant recipients: ultra-high-performance liquid chromatography-tandem ma	12
Blockade of fructose transporter protein GLUT5 inhibits proliferation of colon cancer cells: proof of concept for a new class of anti-tumor therapeutics	12
Plant-derived immuno-adjuvants in vaccines formulation: a promising avenue for improving vaccines efficacy against SARS-CoV-2 virus	12
The effect of poly I:C or LPS priming on the therapeutic efficacy of mesenchymal stem cells in an adjuvant-induced arthritis rat model	12
Correction to: The coming together of allosteric and phosphorylation mechanisms in the molecular integration of A2A heteroreceptor complexes in the dorsal and ventral striatal-pallidal GABA neurons	11
Cytotoxic pathways activated by multifunctional thiosemicarbazones targeting sigma-2 receptors in breast and lung carcinoma cells	11
Correction: Real-world experience with molnupiravir during the period of SARS-CoV-2 Omicron variant dominance	11
Anti-inflammatory activity of novel thiosemicarbazone compounds indole-based as COX inhibitors	11
Correction to: The oxidation and hypoglycaemic effect of sorafenib in streptozotocin-induced diabetic rats	11
Reno-protective effect of protocatechuic acid is independent of sex-related differences in murine model of UUO-induced kidney injury	11
Targeting glucocorticoid receptor signaling pathway for treatment of stress-related brain disorders	10
Correction to: The impact of IL-10 and CYP3A5 gene polymorphisms on dose-adjusted trough blood tacrolimus concentrations in early post-renal transplant recipients	10

Synergistic effect of antibiotics, α-linolenic acid and solvent type against Staphylococcus aureus biofilm formation	10
LY354740, an agonist of glutamatergic metabotropic receptor mGlu2/3 increases the cytochrome P450 2D (CYP2D) activity in the frontal cortical area of rat brain	10
Synthetic free fatty acid receptor (FFAR) 2 agonist 4-CMTB and FFAR4 agonist GSK13764 inhibit colon cancer cell growth and migration and regulate FFARs expression in in vitro and in vivo models of col	10
Oral antiviral treatments for COVID-19: opportunities and challenges	10
Novel method of measurement of in vitro drug uptake in OATP1B3 overexpressing cells in the presence of dextran	9
Identification of mitogen-activated protein kinase phosphatase-1 (MKP-1) protein partners using tandem affinity purification and mass spectrometry	9
Alcohol and breast cancer	9
The study of platelet aggregation using a microtiter plate reader ‒ methodological considerations	9
Berberine and its derivatives represent as the promising therapeutic agents for inflammatory disorders	9
Production and therapeutic use of astaxanthin in the nanotechnology era	9
Critical interactions between opioid and cannabinoid receptors during tolerance and physical dependence development to opioids in the murine gastrointestinal tract: proof of concept	9
Effect of metformin on the long non-coding RNA expression levels in type 2 diabetes: an in vitro and clinical trial study	9
Vascular adhesion protein-1 and microvascular diabetic complications	8
The role of brain gaseous neurotransmitters in anxiety	8
Tannic acid enhances cisplatin effect on cell proliferation and apoptosis of human osteosarcoma cell line (U2OS)	8
The effects of Sorafenib and Natural killer cell co-injection in combinational treatment of hepatocellular carcinoma; an in vivo approach	8
Secondary fungal infections in SARS-CoV-2 patients: pathological whereabouts, cautionary measures, and steadfast treatments	8
An update on mode of action of metformin in modulation of meta-inflammation and inflammaging	8
Neuroprotective effect of apelin-13 and other apelin forms—a review	8
Long-term depression-related tau phosphorylation is enhanced by methylene blue in healthy rat hippocampus	8
Recent review of COVID-19 management: diagnosis, treatment and vaccination	7
The impact of the histone deacetylase inhibitor sodium butyrate on microglial polarization after oxygen and glucose deprivation	7
Uncovering the unique characteristics of different groups of 5-HT5AR ligands with reference to their interaction with the target protein	7
Therapeutic effects of S-allyl-L-cysteine in a mouse endometriosis model and its immunomodulatory effects via regulation of T cell subsets and cytokine expression	7
Therapeutic, diagnostic and prognostic values of TRIM proteins in prostate cancer	7
Correction: Protective effect of hygrolansamycin C against corticosterone-induced toxicity and oxidative stress-mediated via autophagy and the MAPK signaling pathway	7
Partial mGlu5 receptor NAM, M-5MPEP, induces rapid and sustained antidepressant-like effects in the BDNF-dependent mechanism and enhances (R)-ketamine action in mice	7
β-Carboline derivatives are potent against Acute Myeloid Leukemia in vitro and in vivo	7
Fast-acting antidepressant-like effects of ketamine in aged male rats	7
Psilocybin in pharmacotherapy of obsessive-compulsive disorder	7
Soluble dipeptidyl peptidase-4 induces epithelial–mesenchymal transition through tumor growth factor-β receptor	7
Anticonvulsant effects of isopimpinellin and its interactions with classic antiseizure medications and borneol in the mouse tonic–clonic seizure model: an isobolographic transformation	7
Correction to: The impact of atorvastatin on cardiometabolic risk factors in brothers of women with polycystic ovary syndrome	7
Real-world experience with direct-acting antiviral therapy in HCV-infected patients with cirrhosis and esophageal varices	7
Padsevonil suppresses seizures without inducing cell death in neonatal rats	7
Assessing the effects of 5-HT2A and 5-HT5A receptor antagonists on DOI-induced head-twitch response in male rats using marker-less deep learning algorithms	6
Chemical chaperones targeted to the endoplasmic reticulum (ER) and lysosome prevented neurodegeneration in a C9orf72 repeat expansion drosophila amyotrophic lateral sclerosis (ALS) model	6
Metabolic and cardiovascular benefits and risks of 4-hydroxy guanabenz hydrochloride: α2-adrenoceptor and trace amine-associated receptor 1 ligand	6
Extracellular acidification reveals the antiarrhythmic properties of amiodarone related to late sodium current-induced atrial arrhythmia	6
The application of in silico experimental model in the assessment of ciprofloxacin and levofloxacin interaction with main SARS-CoV-2 targets: S-, E- and TMPRSS2 proteins, RNA-dependent RNA polymerase	6
The impact of brivaracetam on cognitive processes and anxiety in various experimental models	6
Genotyping NUDT15*3 rs1166855232 reveals higher frequency of potential adverse effects of thiopurines in Natives and Mestizos from Mexico	6
Multiple sclerosis: a narrative overview of current pharmacotherapies and emerging treatment prospects	6
The effect of phencyclidine-mediated blockade of NMDA receptors in the early postnatal period on glutathione and sulfur amino acid levels in the rat brain as a potential causative factor of schizophre	6
Ursolic acid in colorectal cancer: mechanisms, current status, challenges, and future research directions	6
Cannabidiol attenuates generalized tonic–clonic and suppresses limbic seizures in the genetically epilepsy-prone rats (GEPR-3) strain	6
Short-chain fatty acids–microbiota crosstalk in the coronavirus disease (COVID-19)	6
Evaluation of analgesic and anti-inflammatory activity of purine-2,6-dione-based TRPA1 antagonists with PDE4/7 inhibitory activity	6
Note from editors	6
Imperatorin interacts additively with novel antiseizure medications in the mouse maximal electroshock-induced seizure model: an isobolographic transformation	6
To aspirate or not to aspirate? Considerations for the COVID-19 vaccines	6
Exploring the antiviral activities of the FDA-approved drug sulfadoxine and its derivatives against Chikungunya virus	6
A comprehensive update on the potential of curcumin to enhance chemosensitivity in colorectal cancer	6
Evaluation of the effects of the mGlu2/3 antagonist LY341495 on dyskinesia and psychosis-like behaviours in the MPTP-lesioned marmoset	6
The effect of selected aminoglycoside antibiotics on human serum albumin antioxidant activity: a spectroscopic and calorimetric comparative study	6
Amantadine in the prevention of clinical symptoms caused by SARS-CoV-2	6
Psychedelics action and schizophrenia	6
5-HT2A receptor- and M1 muscarinic acetylcholine receptor-mediated activation of Gαq/11 in postmortem dorsolateral prefrontal cortex of opiate addicts	6
The role of glucagon-like peptide-1/GLP-1R and autophagy in diabetic cardiovascular disease	6
Revisiting the antidepressant-like effects of desipramine in male and female adult rats: sex disparities in neurochemical correlates	6
Novel fluorinated cannabinoid analogs modulate cytokine expression in human C20 microglial cells	6
Health-related quality of life in survivors of severe COVID-19 infection	5
Weighted gene co-expression network analysis for hub genes in colorectal cancer	5
Incidence and control of steroid-induced hyperglycaemia in hospitalised patients at a tertiary care centre for lung diseases	5
The role of GPR39 zinc receptor in the modulation of glutamatergic and GABAergic transmission	5
Drugs with glutamate-based mechanisms of action in psychiatry	5
Formyl peptide receptor 2, as an important target for ligands triggering the inflammatory response regulation: a link to brain pathology	5
Jacareubin inhibits TLR4-induced lung inflammatory response caused by the RBD domain of SARS-CoV-2 Spike protein	5
Effect of common OPRM1, COMT, SLC6A4, ABCB1, and CYP2B6 polymorphisms on perioperative analgesic and propofol demands on patients subjected to thyroidectomy surgery	5
Automated machine learning approach for developing a quantitative structure–activity relationship model for cardiac steroid inhibition of Na+/K+-ATPase	5
Polypharmacology: promises and new drugs in 2022	5
Evaluation of nano-curcumin against inhaled paraquat-induced lung injury in rats	5
Correction to: Nebivolol attenuates the anticonvulsant action of carbamazepine and phenobarbital against the maximal electroshock-induced seizures in mice	5
Nuclear BK channels regulate CREB phosphorylation in RAW264.7 macrophages	5
Relationship between thyroid hormones and central nervous system metabolism in physiological and pathological conditions	5
Modulation of allergic contact dermatitis via gut microbiota modified by diet, vitamins, probiotics, prebiotics, and antibiotics	5
Mechanistic interplay of various mediators involved in mediating the neuroprotective effect of daphnetin	5
Design and optimization various formulations of PEGylated niosomal nanoparticles loaded with phytochemical agents: potential anti-cancer effects against human lung cancer cells	5
Personalization of pharmacotherapy with sirolimus based on volumetric absorptive microsampling (VAMS) in pediatric renal transplant recipients—from LC-MS/MS method validation to clinical application	5
Correction to: The role of childhood adversities, FKBP5, BDNF, NRN1, and generalized self-efficacy in suicide attempts in alcohol-dependent patients	5

Proton pump inhibitor on susceptibility to COVID-19 and its severity: a systematic review and meta-analysis	5
Retinoic acid attenuates nuclear factor kappaB mediated induction of NLRP3 inflammasome	5
In-hospital use of statins is associated with a reduced risk of mortality in coronavirus-2019 (COVID-19): systematic review and meta-analysis	5
Lipid-lowering drugs and cancer: an updated perspective	4
Evaluation of effects of chronic nasal steroid use on rhinological symptoms of COVID-19 with SNOT-22 questionnaire	4
Application of magnetic solid-phase extraction for sensitive determination of anticancer drugs in urine by means of diamino benzidine tetrachlorohydrate modified magnetic nanoparticles	4
Fiber photometry in neuroscience research: principles, applications, and future directions	4
Real-world experience with molnupiravir during the period of SARS-CoV-2 Omicron variant dominance	4
Associations between nesting, stereotypy, and working memory in deer mice: response to levetiracetam	4
Cannabinoid-based therapy as a future for joint degeneration. Focus on the role of CB2 receptor in the arthritis progression and pain: an updated review	4
Insulin in combination with pioglitazone prevents advanced cachexia in 256-Walker tumor-bearing rats: effect is greater than treatment alone and is associated with improved insulin sensitivity	4
Alleviating neuropathy of diabetic foot ulcer by co-delivery of venlafaxine and matrix metalloproteinase drug-loaded cellulose nanofiber sheets: production, in vitro characterization and clinical tria	4
Oridonin enhances antitumor effects of doxorubicin in human osteosarcoma cells	4
Understanding the role of ACE-2 receptor in pathogenesis of COVID-19 disease: a potential approach for therapeutic intervention	4
Pten knockout affects drug resistance differently in melanoma and kidney cancer	4
Selected transgenic murine models of human autoimmune liver diseases	4
RETRACTED ARTICLE: Roflumilast and tadalafil improve learning and memory deficits in intracerebroventricular Aβ1–42 rat model of Alzheimer’s disease through modulations of hippocampal cAMP/cGMP/BDNF s	4
Special issue: Glutamate– physiology, pathology, therapy	4
The impact of IL-10 and CYP3A5 gene polymorphisms on dose-adjusted trough blood tacrolimus concentrations in early post-renal transplant recipients	4
Interactions between metabotropic glutamate and CB1 receptors: implications for mood, cognition, and synaptic signaling based on data from mGluR and CB1R-targeting drugs	4
The impact of noradrenergic neurotoxin DSP-4 and noradrenaline transporter knockout (NET-KO) on the activity of liver cytochrome P450 3A (CYP3A) in male and female mice	4
Pharmacogenomics of statins: lipid response and other outcomes in Brazilian cohorts	4
Sigma receptors and neurological disorders	4
N-acetylcysteine in substance use disorder: a lesson from preclinical and clinical research	4
Treatment with dopamine β-hydroxylase (DBH) inhibitors prevents morphine use and relapse-like behavior in rats	4
The effect of sulindac on redox homeostasis and apoptosis-related proteins in melanotic and amelanotic cells	4
Astaxanthin has a beneficial influence on pain-related symptoms and opioid-induced hyperalgesia in mice with diabetic neuropathy-evidence from behavioral studies	4
Antidepressant effects of selective adenosine receptor antagonists targeting the A1 and A2A receptors administered jointly with NMDA receptor ligands: behavioral, biochemical and molecular investigati	4
Access to high-fat diet results in increased sensitivity to the psychostimulant effects of MDPV in mice	4
Obesity-related drug transporter expression alterations in human liver and kidneys	4
Metabotropic glutamate receptors—guardians and gatekeepers in neonatal hypoxic-ischemic brain injury	4
Significant pharmacological activities of benzoquinazolines scaffold	4
Therapeutic implication of Sonic Hedgehog as a potential modulator in ischemic injury	4
HDAC3 inhibition protects against peripheral and central alterations in an animal model of obesity	4
Glycolytic metabolism supports microglia training during age-related neurodegeneration	4
Three novel piperidones exhibit tumor-selective cytotoxicity on leukemia cells via protein degradation and stress-mediated mechanisms	3
Tolerability of N-chlorotaurine in comparison with routinely used antiseptics: an in vitro study on chondrocytes	3
Effect of vitamin D supplementation on OPG/RANKL signalling activities in endothelial tissue damage in diet-induced diabetic rat model	3
L-proline transporter inhibitor (LQFM215) promotes neuroprotection in ischemic stroke	3
Impaired metabolic effects of metformin in men with early-onset androgenic alopecia	3
Remdesivir and SARS-CoV-2 monoclonal antibodies to prevent COVID-19 progression in hematological patients: an observational study	3
Rho-associated kinases contribute to the regulation of tau phosphorylation and amyloid metabolism during neuronal plasticity	3
The differential functional coupling of phosphodiesterase 4 to human DP and EP2 prostanoid receptors stimulated with PGD2 or PGE2	3
Can research on entactogens contribute to a deeper understanding of human sexuality?	3
Comparing efficacy and safety of different doses of dexamethasone in the treatment of COVID-19: a three-arm randomized clinical trial	3
The influence of cyclooxygenase inhibitors on kynurenic acid production in rat kidney: a novel path for kidney protection?	3
Ginsenoside Rg5 as an anticancer drug: a comprehensive review on mechanisms, structure–activity relationship, and prospects for clinical advancement	3
Mitochondrial targeted antioxidants as potential therapy for huntington’s disease	3
Changes in expression of mesothelial BBS genes in 2D and 3D after lithium chloride and ammonium sulphate induction of primary cilium disturbance: a pilot study	3
High-performance liquid chromatography with fluorescence detection for mycophenolic acid determination in saliva samples	3
Effects of chronic fluoxetine treatment on anxiety- and depressive-like behaviors in adolescent rodents – systematic review and meta-analysis	3
Interaction between moxifloxacin and Mcl-1 and MITF proteins: the effect on growth inhibition and apoptosis in MDA-MB-231 human triple-negative breast cancer cells	3
Novel adenosine derivatives against SARS-CoV-2 RNA-dependent RNA polymerase: an in silico perspective	3
Surface-functionalized curcumin-loaded polymeric nanocapsules could block apomorphine-induced behavioral changes in rats	3
Transcriptome analysis of an AKT inhibitor-resistant endometrial cancer cell line	3
The long-term effects of multidrug immunosuppressive protocols based on calcineurin inhibitors and conversion to rapamycin on the morphology, apoptosis, and proliferation of rat salivary glands	3
Effects of long-term infliximab and tocilizumab treatment on anxiety-like behavior and cognitive function in naive rats	3
The effect of valproate on the amino acids, monoamines, and kynurenic acid concentrations in brain structures involved in epileptogenesis in the pentylenetetrazol-kindled rats	3
Efficacy of COVID-19 vaccines: a systematic review and network meta-analysis of phase 3 randomized controlled trials	3
Proton pump inhibitor-induced gut dysbiosis and immunomodulation: current knowledge and potential restoration by probiotics	3
Effects of Gαi2 and Gαz protein knockdown on alpha2A-adrenergic and cannabinoid CB1 receptor regulation of MEK-ERK and FADD pathways in mouse cerebral cortex	3
JNK signaling as a target for anticancer therapy	3
An in vitro evaluation of the antioxidant activities of necroptosis and apoptosis inhibitors: the potential of necrostatin-1 and necrostatin-1i to have radical scavenging activities	3
Hepatic drug-metabolizing enzymes and drug transporters in Wilson’s disease patients with liver failure	3
Acetaminophen treatment evokes anticontractile effects in rat aorta by blocking L-type calcium channels	3
Acknowledgments	3
The possible pathogenesis of liver fibrosis: therapeutic potential of natural polyphenols	3
Integrative opioid-GABAergic neuronal mechanisms regulating dopamine efflux in the nucleus accumbens of freely moving animals	2
Regulatory effects of resveratrol on nitric oxide signaling in cardiovascular diseases	2
Enhanced hippocampal TIAM2S expression alleviates cognitive deficits in Alzheimer’s disease model mice	2
Melatonin and oral diseases: possible therapeutic roles based on cellular mechanisms	2
Recent progress in biologically active indole hybrids: a mini review	2
Gαi-derived peptide binds the µ-opioid receptor	2
Preclinical efficacy of cannabidiol for the treatment of early-life seizures	2
Identification of genes regulated by trait sensitivity to negative feedback and prolonged alcohol consumption in rats	2
Chlorpromazine affects the numbers of Sox-2, Musashi1 and DCX-expressing cells in the rat brain subventricular zone	2
In vivo evaluation of a microtubule PET ligand, [11C]MPC-6827, in mice following chronic alcohol consumption	2
Safety of dapagliflozin and empagliflozin in cases with diabetes mellitus or/and heart failure: a retrospective pharmacovigilance study conducted on the eudravigilance database	2
The future of metronomic chemotherapy: experimental and computational approaches of drug repurposing	2
Modulation of DNA damage response by targeting ATM kinase using newly synthesized di-phenoxy acetamide (DPA) analogs to induce anti-neoplasia	2
Repetitive transcranial direct current stimulation modulates the brain–gut–microbiome axis in obese rodents	2
A role for macrophages under cytokine control in mediating resistance to ADI-PEG20 (pegargiminase) in ASS1-deficient mesothelioma	2
Pharmacologic hyperreactivity of kappa opioid receptors in periaqueductal gray matter during alcohol withdrawal syndrome in rats	2
Nano-antibiotic based on silver nanoparticles functionalized to the vancomycin–cysteamine complex for treating Staphylococcus aureus and Enterococcus faecalis	2
The ixabepilone and vandetanib combination shows synergistic activity in docetaxel-resistant MDA-MB-231 breast cancer cells	2
Special issue “role of G-proteins and GPCR-mediated signaling in the pathophysiology and treatment of psychiatric disorders”	2
Acute anticonvulsant effects of dapsone on PTZ- and MES-induced seizures in mice: NLRP3 inflammasome inhibition and Nrf2/HO-1 pathway preservation	2
Select terpenes from Cannabis sativa are antinociceptive in mouse models of post-operative pain and fibromyalgia via adenosine A2a receptors	2
Inhibition of CHI3L1 decreases N-cadherin and VCAM-1 levels in glioblastoma	2
Therapeutic potential of melatonin in targeting molecular pathways of organ fibrosis	2
Anticancer potential of osthole: targeting gynecological tumors and breast cancer	2
Novel serotonin 5-HT2A receptor antagonists derived from 4-phenylcyclohexane-5-spiro-and 5-methyl-5-phenyl-hydantoin, for use as potential antiplatelet agents	2
The selective cytotoxicity of silver thiosulfate, a silver complex, on MCF-7 breast cancer cells through ROS-induced cell death	2
Drug repositioning: diacerein as a new therapeutic approach in a mice model of sciatic nerve injury	2
Determination of bisphosphonate properties in terms of bioavailability, bone affinity, and cytotoxicity	2