Aging Clinical and Experimental Research

Article	Citations
The role of vitamin D in the prevention of coronavirus disease 2019 infection and mortality	502
COVID-19 and the elderly: insights into pathogenesis and clinical decision-making	244
The potential long-term impact of the COVID-19 outbreak on patients with non-communicable diseases in Europe: consequences for healthy ageing	232
Post-COVID-19 global health strategies: the need for an interdisciplinary approach	132
Internet of things (IoT) applications for elderly care: a reflective review	118
Post-COVID-19 acute sarcopenia: physiopathology and management	112
Urinary incontinence and quality of life: a systematic review and meta-analysis	99
Evidence for possible association of vitamin D status with cytokine storm and unregulated inflammation in COVID-19 patients	98
COVID-19 in older adults	90
Aging tsunami coming: the main finding from China’s seventh national population census	81
Clinical characteristics, laboratory outcome characteristics, comorbidities, and complications of related COVID-19 deceased: a systematic review and meta-analysis	77
Delirium in COVID-19: epidemiology and clinical correlations in a large group of patients admitted to an academic hospital	70
Pathophysiology and treatment of osteoporosis: challenges for clinical practice in older people	64
Alternative and complementary therapies in osteoarthritis and cartilage repair	62
Vitamin D supplementation: upper limit for safety revisited?	56
Approaches to the diagnosis and prevention of frailty	56
A review on the COVID-19-related psychological impact on older adults: vulnerable or not?	53
Severe vitamin D deficiency is not related to SARS-CoV-2 infection but may increase mortality risk in hospitalized adults: a retrospective case–control study in an Arab Gulf country	52
Perioperative Management of Elderly patients (PriME): recommendations from an Italian intersociety consensus	52
Determinants of healthy ageing: a systematic review of contemporary literature	50
COVID-19 and associations with frailty and multimorbidity: a prospective analysis of UK Biobank participants	50
Prevalence of sarcopenia according to EWGSOP1 and EWGSOP2 in older adults and their associations with unfavorable health outcomes: a systematic review	48
Prognostic value of geriatric nutritional risk index in elderly patients with heart failure: a meta-analysis	48
Knee osteoarthritis and time-to all-cause mortality in six community-based cohorts: an international meta-analysis of individual participant-level data	47
Cytokine storm in aged people with CoV-2: possible role of vitamins as therapy or preventive strategy	44

Differences in the clinical characteristics of COVID-19 patients who died in hospital during different phases of the pandemic: national data from Italy	43
The Montreal Cognitive Assessment (MoCA): updated norms and psychometric insights into adaptive testing from healthy individuals in Northern Italy	42
Green space exposure on mortality and cardiovascular outcomes in older adults: a systematic review and meta-analysis of observational studies	40
Update on the ESCEO recommendation for the conduct of clinical trials for drugs aiming at the treatment of sarcopenia in older adults	40
Improving the care of older patients during the COVID-19 pandemic	39
Incidence and associated factors of delirium after orthopedic surgery in elderly patients: a systematic review and meta-analysis	38
Inflammatory biomarkers in older adults with frailty: a systematic review and meta-analysis of cross-sectional studies	37
Defining the characteristics of intermediate care models including transitional care: an international Delphi study	35
Effects of short- and long-term neurostimulation (tDCS) on Alzheimer’s disease patients: two randomized studies	32
Patterns of multimorbidity and risk of disability in community-dwelling older persons	32
Mediterranean diet adherence is associated with better cognitive status and less depressive symptoms in a Greek elderly population	32
Highly purified chondroitin sulfate: a literature review on clinical efficacy and pharmacoeconomic aspects in osteoarthritis treatment	32
Prognostic role of nutritional status in elderly patients hospitalized for COVID-19: a monocentric study	31
The psychological and cognitive impact of Covid-19 on individuals with neurocognitive impairments: research topics and remote intervention proposals	31
The diversity of gut microbiota in type 2 diabetes with or without cognitive impairment	30
Management of patients at very high risk of osteoporotic fractures through sequential treatments	30
Osteosarcopenia, the co-existence of osteoporosis and sarcopenia, is associated with social frailty in older adults	30
Integrated care for the management of ageing-related non-communicable diseases: current gaps and future directions	29
Mitochondrial DNA deletion mutations increase exponentially with age in human skeletal muscle	29
Neurofilament light chain concentration in an aging population	29
Dairy products and bone health	29
The effects of dementia on the prognosis and mortality of hip fracture surgery: a systematic review and meta-analysis	28
Handgrip strength asymmetry is associated with future falls in older Americans	28
From cognitive to motor impairment and from sarcopenia to cognitive impairment: a bidirectional pathway towards frailty and disability	28
Evidence-based recommendations for resistance and power training to prevent frailty in community-dwellers	27
Postoperative delirium after cardiac surgery of elderly patients as an independent risk factor for prolonged length of stay in intensive care unit and in hospital	27
Revisiting the role of vitamin D levels in the prevention of COVID-19 infection and mortality in European countries post infections peak	26
Using the Multidimensional Prognostic Index (MPI) to improve cost-effectiveness of interventions in multimorbid frail older persons: results and final recommendations from the MPI_AGE European Project	26
The role of neurofilament light chain in frontotemporal dementia: a meta-analysis	25
Effectiveness and feasibility of home-based telerehabilitation for community-dwelling elderly people in Southeast Asian countries and regions: a systematic review	25
Vitamin D and coronavirus disease 2019 (COVID-19): rapid evidence review	25
Impact of exercise training on muscle mitochondria modifications in older adults: a systematic review of randomized controlled trials	25
Guidelines on exercise testing and prescription for patients at different stages of Parkinson’s disease	25
The effect of ageing on skeletal muscle as assessed by quantitative MR imaging: an association with frailty and muscle strength	24
Platelet-to-lymphocyte ratio relates to poor prognosis in elderly patients with acute myocardial infarction	24
The impact of COVID-19 on health status of home-dwelling elderly patients with dementia in East Lombardy, Italy: results from COVIDEM network	24
Role of bone-forming agents in the management of osteoporosis	23
Diaphragmatic muscle thickness in older people with and without sarcopenia	23
ICT technologies as new promising tools for the managing of frailty: a systematic review	22
Italian guidelines on management of persons with multimorbidity and polypharmacy	22
The association of marital status with cognitive function and the role of gender in Chinese community-dwelling older adults: a cross-sectional study	22
Role of vitamin D supplementation in the management of musculoskeletal diseases: update from an European Society of Clinical and Economical Aspects of Osteoporosis, Osteoarthritis and Musculoskeletal	22
Video-based learning versus traditional lecture-based learning for osteoporosis education: a randomized controlled trial	21
Clinical assessment of gait and functional mobility in Italian healthy and cognitively impaired older persons using wearable inertial sensors	21
Cognitive dysfunction correlates with physical impairment in frail patients with acute myocardial infarction	21
Association between frailty index, lung function, and major clinical determinants in chronic obstructive pulmonary disease	21
Prevalence and impact of polypharmacy in older patients with type 2 diabetes	20
SARC-F as a case-finding tool for sarcopenia according to the EWGSOP2. National validation and comparison with other diagnostic standards	20
Management of glucocorticoid-induced osteoporosis	20
Physical activity as a determinant of successful aging: a narrative review article	20

Intranasal delivery of BDNF rescues memory deficits in AD11 mice and reduces brain microgliosis	20
Association between alcohol intake, mild cognitive impairment and progression to dementia: a dose–response meta-analysis	20
World Congress on Osteoporosis, Osteoarthritis and Musculoskeletal Diseases (WCO-IOF-ESCEO 2023)	20
Prevalence of COVID-19-related symptoms by age group	19
Sarcopenia, immune-mediated rheumatic diseases, and nutritional interventions	19
Effects of dance therapy on non-motor symptoms in patients with Parkinson’s disease: a systematic review and meta-analysis	19
World Congress on Osteoporosis, Osteoarthritis and Musculoskeletal Diseases (WCO-IOF-ESCEO 2022)	19
Management of hip fracture in the older people: rationale and design of the Italian consensus on the orthogeriatric co-management	19
Frailty, walking ability and self-rated health in predicting institutionalization: an 18-year follow-up study among Finnish community-dwelling older people	19
The prevalence and co-incidence of geriatric syndromes in older patients with early-stage Alzheimer’s disease and dementia with Lewy bodies	19
Unplanned hospital transfers from nursing homes: who is involved in the transfer decision? Results from the HOMERN study	19
Association between anticholinergic burden and oropharyngeal dysphagia among hospitalized older adults	19
Premorbid vulnerability and disease severity impact on Long-COVID cognitive impairment	19
Gender differences in the association between physical activity and health-related quality of life among community-dwelling elders	18
Management of osteoporosis in older men	18
The role of health determinants in the influenza vaccination uptake among older adults (65+): a scope review	18
Oral diadochokinesis is related to decline in swallowing function among community-dwelling Japanese elderly: a cross-sectional study	18
Does vitamin D improve symptomatic and structural outcomes in knee osteoarthritis? A systematic review and meta-analysis	18
Stay fit, don't quit: Geriatric Exercise Prescription in COVID-19 Pandemic	18
Psychometric properties of the STAI-Y scales and normative data in an Italian elderly population	18
Sarcopenia quality-of-life questionnaire (SarQoL)®: translation, cross-cultural adaptation and validation in Turkish	18
The effect of resistance training programs on lean body mass in postmenopausal and elderly women: a meta-analysis of observational studies	18
Static one-leg standing balance test as a screening tool for low muscle mass in healthy elderly women	18
The role of inflammation and metabolic risk factors in the pathogenesis of calcific aortic valve stenosis	18
The effect of combined cognitive intervention and physical exercise on cognitive function in older adults with mild cognitive impairment: a meta-analysis of randomized controlled trials	18
Malnutrition, assessed by the Global Leadership Initiative on Malnutrition (GLIM) criteria but not by the mini nutritional assessment (MNA), predicts the incidence of sarcopenia over a 5-year period i	17
Volunteer-led physical activity interventions to improve health outcomes for community-dwelling older people: a systematic review	17
Simple oral exercise with chewing gum for improving oral function in older adults	17
Uric acid and late-onset Alzheimer’s disease: results from the ReGAl 2.0 project	17
Cardiovascular safety of calcium, magnesium and strontium: what does the evidence say?	17
Norms and equivalences for MoCA-30, MoCA-22, and MMSE in the oldest-old	17
The effectiveness of traditional Chinese medicine-based exercise on physical performance, balance and muscle strength among older adults: a systematic review with meta-analysis	16
Group-based physical activity as a means to reduce social isolation and loneliness among older adults	16
Can cognitive-motor training improve physical functioning and psychosocial wellbeing in nursing home residents? A randomized controlled feasibility study as part of the PROCARE project	16
Dietary inflammatory potential and biological aging among US adults: a population-based study	16
Task specificity impacts dual-task interference in older adults	16
Mortality attributable to COVID-19 in nursing home residents: a retrospective study	16
Frailty prevalence according to the Survey of Health, Ageing and Retirement in Europe-Frailty Instrument (SHARE-FI) definition, and its variables associated, in patients with symptomatic knee osteoart	16
A double-blind randomized controlled trial of the efficacy of cognitive training delivered using two different methods in mild cognitive impairment in Parkinson’s disease: preliminary report of benefi	16
Skeletal muscle weakness in older adults home-restricted due to COVID-19 pandemic: a role for full-body in-bed gym and functional electrical stimulation	16
Rewinding sarcopenia: a narrative review on the renin–angiotensin system	16
Frailty but not sarcopenia nor malnutrition increases the risk of developing COVID-19 in older community-dwelling adults	15
Impact of nutraceuticals and dietary supplements on mitochondria modifications in healthy aging: a systematic review of randomized controlled trials	15
Evaluating the systemic immune-inflammation index for in-hospital and long-term mortality in elderly non-ST-elevation myocardial infarction patients	15
Adverse cardiovascular magnetic resonance phenotypes are associated with greater likelihood of incident coronavirus disease 2019: findings from the UK Biobank	15
Handgrip strength predicts length of hospital stay in an abdominal surgical setting: the role of frailty beyond age	15
Efficacy and efficiency of fracture liaison services to reduce the risk of recurrent osteoporotic fractures	15
Association between low vitamin D and COVID-19: don’t forget the vitamin D binding protein	15
The effect of mind–body exercise on memory in older adults: a systematic review and meta-analysis	15
Associations between hypovitaminosis D and COVID-19: a narrative review	15
Does a lack of vaccine side effects correlate with reduced BNT162b2 mRNA vaccine response among healthcare workers and nursing home residents?	15
LACE index predicts age-specific unplanned readmissions and mortality after hospital discharge	14
Safety and tolerability of 6-month supplementation with a vitamin D, calcium and leucine-enriched whey protein medical nutrition drink in sarcopenic older adults	14
Responsiveness to muscle mass gain following 12 and 24 weeks of resistance training in older women	14
Predictors for functional decline after an injurious fall: a population-based cohort study	14
Attributes and definitions of locomotor capacity in older people: a World Health Organisation (WHO) locomotor capacity working group meeting report	14
Birth cohort differences in cognitive performance in 75- and 80-year-olds: a comparison of two cohorts over 28 years	14
Factors predicting the severity of acute pancreatitis in elderly patients	14
Life satisfaction in late adult span: the contribution of family relationships, health self-perception and physical activity	14
Does the association of therapeutic exercise and supplementation with sucrosomial magnesium improve posture and balance and prevent the risk of new falls?	14
How great is the negative impact of masking and social distancing and how can we enhance communication skills in the elderly people?	14
Multidimensional Prognostic Index (MPI) in elderly patients with acute myocardial infarction	14
Nutritional status mediates the relationship between sarcopenia and cognitive impairment: findings from the WCHAT study	14
Prevalence and incidence of iron deficiency in European community-dwelling older adults: an observational analysis of the DO-HEALTH trial	14
Clinical and demographic parameters predict the progression from mild cognitive impairment to dementia in elderly patients	13
Nordic Walking and Walking in Parkinson’s disease: a randomized single-blind controlled trial	13
The comparison of GNRI and other nutritional indexes on short-term survival in geriatric patients treated for respiratory failure	13
Serum alkaline phosphatase is elevated and inversely correlated with cognitive functions in subjective cognitive decline: results from the ReGAl 2.0 project	13
Ishii test for screening sarcopenia: performance in community-dwelling older adults	13
Electroencephalogram in dementia with Lewy bodies: a systematic review	13
Comorbidity and the association with 1-year mortality in hip fracture patients: can the ASA score and the Charlson Comorbidity Index be used interchangeably?	13
Prevalence, physical characteristics, and fall risk in older adults with and without possible sarcopenia	13
Living alone vs. living with someone as a predictor of mortality after a bone fracture in older age	13
Does skeletal muscle morphology or functional performance better explain variance in fast gait speed in older adults?	13
Ability of radiofrequency echographic multispectrometry to identify osteoporosis status in elderly women with type 2 diabetes	13
The effect of different test protocols and walking distances on gait speed in older persons	13
Aging hampers neutrophil extracellular traps (NETs) efficacy	13
Effect of COVID-19 quarantine on cognitive, functional and neuropsychiatric symptoms in patients with mild cognitive impairment and dementia	12
Trimodal prehabilitation for older surgical patients: a systematic review and meta-analysis	12
Neuropsychology of posteromedial parietal cortex and conversion factors from Mild Cognitive Impairment to Alzheimer’s disease: systematic search and state-of-the-art review	12

The identification of established modifiable mid-life risk factors for cardiovascular disease which contribute to cognitive decline: Korean Longitudinal Study of Aging (KLoSA)	12
Emergency laparotomy in the older patient: factors predictive of 12-month mortality—Salford-POPS-GS. An observational study	12
Older cancer patients receiving radiotherapy: a systematic review for the role of sarcopenia in treatment outcomes	12
Serum testosterone and obesity in prostate cancer biology: a call for health promotion in the ageing male	12
Characteristics of community-based exercise programs for community-dwelling older adults in rural/regional areas: a scoping review	12
2021 revised algorithm for the management of knee osteoarthritis—the Chinese viewpoint	12
Validation and implementation of telephone-administered version of the Multidimensional Prognostic Index (TELE-MPI) for remote monitoring of community-dwelling older adults	12
The effect of ageing on fat infiltration of thigh and paraspinal muscles in men	12
Oral factors and adherence to Mediterranean diet in an older Greek population	12
Clinical trial on the effects of oral magnesium supplementation in stable-phase COPD patients	12
Association of fatigue, inflammation, and physical activity on gait speed: the Long Life Family Study	12
Direct anterior approach versus direct lateral approach in total hip arthroplasty and bipolar hemiarthroplasty for femoral neck fractures: a retrospective comparative study	11
Impact of sarcopenia on daily functioning: a cross-sectional study among older inpatients	11
Prophylactic or therapeutic doses of heparins for COVID-19 infection? A retrospective study	11
Hypoglycaemic therapy in frail older people with type 2 diabetes mellitus—a choice determined by metabolic phenotype	11
Relationship between frailty and drug use among nursing homes residents: results from the SHELTER study	11
Inflammatory markers in postoperative cognitive dysfunction for patients undergoing total hip arthroplasty: a meta-analysis	11
Frailty and long-term survival of patients with colorectal cancer: a meta-analysis	11
Orthogeriatric co-management for the care of older subjects with hip fracture: recommendations from an Italian intersociety consensus	11
Lipopolysaccharide binding protein is associated with CVD risk in older adults	11
Do older patients (> 80 years) also benefit from ERAS after colorectal resection? A safety and feasibility study	11
Estimating COVID-19-induced excess mortality in Lombardy, Italy	11
Sulfonylureas use and fractures risk in elderly patients with type 2 diabetes mellitus: a meta-analysis study	11
Comorbidity status of deceased COVID-19 in-patients in Italy	11
Linear association between grip strength and all-cause mortality among the elderly: results from the SHARE study	11
Charlson Comorbidity Index as a predictor of repeated hospital admission and mortality among older women diagnosed with cardiovascular disease	11
Knee osteoarthritis and adverse health outcomes: an umbrella review of meta-analyses of observational studies	11
A double-blind randomized controlled trial combining cognitive training (CoRe) and neurostimulation (tDCS) in the early stages of cognitive impairment	10
Nutrition and exercise interventions could ameliorate age-related cognitive decline: a meta-analysis of randomized controlled trials	10
Evidence based Latin American Guidelines of clinical practice on prevention, diagnosis, management and treatment of glucocorticoid induced osteoporosis. A 2022 update	10
The impact of physical activity on blood inflammatory cytokines and neuroprotective factors in individuals with mild cognitive impairment: a systematic review and meta-analysis of randomized-controlle	10
Geriatric co-management and interdisciplinary transitional care reduced hospital readmissions in frail older patients in Argentina: results from a randomized controlled trial	10
Cognitive behavioral therapy cannot relieve postoperative pain and improve joint function after total knee arthroplasty in patients aged 70 years and older	10
Neuroimaging markers of chronic fatigue in older people: a narrative review	10
Daytime versus after-hours surgery outcomes in hip fracture patients: a systematic review and meta-analysis	10
Associations between nutritional factors and excessive daytime sleepiness in older patients with chronic kidney disease	10
Muscle strength cutoff values calculated from the young reference population to evaluate sarcopenia in Turkish population	10
Closeness to friends explains age differences in positive emotional experience during the lockdown period of COVID-19 pandemic	10
Association between Healthy Eating Index-2015 and physical frailty among the United States elderly adults: the National Health and Nutrition Examination Survey (NHANES) 2011–2014	10
The relationship between extracellular water-to-body water ratio and sarcopenia according to the newly revised Asian Working Group for Sarcopenia: 2019 Consensus Update	10
Metabolic syndrome predicts incident disability and functional decline among Chinese older adults: results from the China Health and Retirement Longitudinal Study	10
Iron deficiency and biomarkers of inflammation: a 3-year prospective analysis of the DO-HEALTH trial	10
The effects of dietary licorice flavonoid oil supplementation on body balance control in healthy middle-aged and older Japanese women undergoing a physical exercise intervention: a randomized, double-	10
Relationship between self-reported visual impairment and worsening frailty transition states in older people: a longitudinal study	10
Clinical determinants of low handgrip strength and its decline in the oldest old: the Leiden 85-plus Study	10
Raising awareness of the needs of older COVID patients after hospital discharge	10
Improving vaccination rates in older adults and at-risk groups: focus on pertussis	10
The role of collaborative, multistakeholder partnerships in reshaping the health management of patients with noncommunicable diseases during and after the COVID-19 pandemic	10
The Emergency Surgery Frailty Index (EmSFI): development and internal validation of a novel simple bedside risk score for elderly patients undergoing emergency surgery	10
Pharmacokinetic profile and effect on bone markers and muscle strength of two daily dosage regimens of calcifediol in osteopenic/osteoporotic postmenopausal women	9
Advance care planning and advance directives: an overview of the main critical issues	9
Identifying peripheral arterial disease in the elderly patients using machine-learning algorithms	9
The role of sarcopenia questionnaires in hospitalized patients with chronic heart failure	9
Association of preoperative frailty with postoperative delirium in elderly orthopedic trauma patients	9
Migraine and the risk of dementia: a meta-analysis and systematic review	9
Networks of inflammation, depression, and cognition in aging males and females	9
Depressive symptoms predict low physical performance among older Mexican Americans	9
Clustering of patients with end-stage chronic diseases by symptoms: a new approach to identify health needs	9
What does hand motor function tell us about our aging brain in association with WMH?	9
Dietary creatine and cognitive function in U.S. adults aged 60 years and over	9
Verification of the predictive validity for mortality of the SARC-F questionnaire based on a meta-analysis	9
Caring for nursing home residents with COVID-19: a “hospital-at-nursing home” intermediate care intervention	9
Differences in lower limb muscle strength and balance ability between sarcopenia stages depend on sex in community-dwelling older adults	8
Falls and life-space mobility: longitudinal analysis from The International Mobility in Aging Study	8
Italian telephone-based Mini-Mental State Examination (Itel-MMSE): item-level psychometric properties	8
The Mini Sarcopenia Risk Assessment (MSRA) Questionnaire score as a predictor of skeletal muscle mass loss	8
Association between frailty and postoperative delirium: a meta-analysis of cohort study	8
A multifactorial intervention to lower potentially inappropriate medication use in older adults in Argentina	8
A comprehensive review of machine learning algorithms and their application in geriatric medicine: present and future	8
Serum sestrins: potential predictive molecule in human sarcopenia	8
Prevalence of obesity and diabetes in older people with sarcopenia defined according to EWGSOP2 and FNHI criteria	8
Novel formulations of oral bisphosphonates in the treatment of osteoporosis	8
Carotid intima-media thickness in patients with hyperuricemia: a systematic review and meta-analysis	8
Vitamin D status and COVID-19 in older adults	8
What about the caregiver? A journey into Parkinson’s disease following the burden tracks	8
Changes in physical activity levels and relationship to balance performance, gait speed, and self-rated health in older Swedish women: a longitudinal study	8
Cognitive, physical and disability trajectories in community-dwelling elderly people	8
Incidence and risk factors associated with surgical site infection after surgically treated hip fractures in older adults: a retrospective cohort study	8
The association between fear of falling and orthostatic hypotension in older adults	8
TOMM40 and APOE variants synergistically increase the risk of Alzheimer’s disease in a Chinese population	8
2019 revised algorithm for the management of knee osteoarthritis: the Southeast Asian viewpoint	8
Nursing home leaders’ perceptions of a research partnership	8
Sleeping time is associated with functional limitations in a national sample of older Americans	8
Prevalence and management of delirium in community dwelling older people with dementia referred to a memory clinic	8
Influencing factors for the decline of limb muscle strength and the association with all-cause mortality: evidence from a nationwide population-based cohort study	8
The prevalence of undernutrition and associated factors in older obese patients	8
Application of integrated management bundle incorporating with multidisciplinary measures improved in-hospital outcomes and early survival in geriatric hip fracture patients with perioperative heart f	8
Clinical outcomes of geriatric patients with COVID-19: review of one-year data	8
Association of sarcopenia and physical activity with functional outcome in older Asian patients hospitalized for rehabilitation	8
Longitudinal white matter hyperintensity changes and cognitive decline in patients with minor stroke	8
Age-related composition changes in swallowing-related muscles: a Dixon MRI study	8
Multiple domains of functioning in older adults during the pandemic: design and basic characteristics of the Longitudinal Aging Study Amsterdam COVID-19 questionnaire	8
Delirium screening tools in the post-anaesthetic care unit: a systematic review and meta-analysis	8
Are we maximizing the utility of handgrip strength assessments for evaluating muscle function?	8
Barriers and enablers associated with participation in a home-based pragmatic exercise snacking program in older adults delivered and monitored by Amazon Alexa: a qualitative study	8