OOIR: Observatory of International Research

Papers

(The median citation count of Journal of Applied Oral Science is 2. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-05-01 to 2026-05-01.)

Article	Citations
Longitudinal bond strength of a universal adhesive and chemical dentin characterization under different acid etching protocols	28
Single local injection of 3S-HMGB1 enhances early bone healing and titanium implant osseointegration in type 2 diabetic mice	22
Relation between the risk factors for the severity of denture stomatitis and quality of life of complete edentulous individuals: a cross-sectional study	22
1,25(OH)2D3 increase osteogenic potential of human periodontal ligament cells with low osteoblast potential*	22
Apical delta filling with calcium silicate and epoxy resin sealers using different obturation techniques by microcomputed tomography	21
Maqui berry cystatin inhibits cathepsin k activity and stimulates osteogenic differentiation of human dental pulp cells	19
Immunomodulatory effects of apical papilla cells on periodontal ligament fibroblasts stimulated with Escherichia coli lipopolysaccharide: an in vitro study	19
Microbial signatures in head and neck squamous cell carcinoma: an in silico study	16
Immunoexpression profile of hypoxia-inducible factor (HIF) targets in potentially malignant and malignant oral lesions: a pilot study	14
Does radiation therapy affect adhesion of tricalcium silicate cements to root dentin?	13
Association between the Mediterranean Diet Index and self-reported Gingival Health Status Indicators in a population of Chilean adults: a cross-sectional study	13
Influence of molar incisor hypomineralisation severity on dental hypersensitivity, anxiety/fear, and aesthetic self-perception: a cross-sectional study	13
Investigating the association between dental age and polymorphisms in genes encoding estrogen receptors	12
Novel approach to soft tissue regeneration: in vitro study of compound hyaluronic acid and horizontal platelet-rich fibrin combination	12
Notch2 is involved in regulating apical tissue repair following severe intrusive luxation	12
DNA methyltransferases expressions in mice tongue exposed to waterpipe smoke	12
Colonization dynamics of subgingival microbiota in recently installed dental implants compared to healthy teeth in the same individual: a 6-month prospective observational study	12
Injectable platelet rich fibrin effect on laser depigmented gingiva: a clinical randomized controlled split mouth trial with histological assessment	12
Monocytes and Macrophage-derived mediators influence the behavior of squamous cell carcinoma cell lines	11
Periodontal disease severity is associated to pathogenic consortia comprising putative and candidate periodontal pathogens	10
Biocompatibility and bioactivity of bioceramic endodontic sealer: NeoSealer Flo	10
Comprehensive analysis of transcriptome and pathway interactions in periodontitis	10
Rinsing solutions containing natural extracts and fluoride prevent enamel erosion in vitro	10
Effects of systemic Anatolian propolis administration on a rat-irradiated osteoradionecrosis model	10
Synergistic antimicrobial potential of EGCG and fosfomycin against biofilms associated with endodontic infections	10

The action of microbial collagenases in dentinal matrix degradation in root caries and potential strategies for its management: a comprehensive state-of-the-art review	10
Outcomes of permanent canines on the cleft side after secondary alveolar grafting using different materials in complete unilateral cleft lip and palate	9
Biomimetic Restorative Dentistry: an evidence-based discussion of common myths	9
Comparison of TiF4, CPP-ACP, and NaF in preventing demineralization in irradiated bovine enamel and dentin in vitro	9
Synergistic effect of Maquiberry cystatin, sodium fluoride and stannous chloride for the prevention of initial dental erosion in vitro	9
The simultaneous miR-155-5p overexpression and miR-223-3p inhibition can activate pEMT in oral squamous cell carcinoma	9
Evaluation of radiation therapy on grafted and non-grafted defects: an experimental rat model	9
Healing effect of curcumin on tooth extraction sockets in diabetic rats	8
Influence of impacted mandibular third molars on pathological changes on themselves and adjacent tissues across different age groups: a cross-sectional study	8
Saliva liquid biopsy: MMP2, MMP9, and TIMP2 as potential diagnostic biomarkers in oral squamous cell carcinoma. An observational case-control study	8
Different concentrations of fetal bovine serum affect cytokine modulation in Lipopolysaccharide-activated apical papilla cells in vitro	8
Influence of the combined effect of desensitizing dentifrices and universal adhesives on dentin bond strength under erosive conditions	8
The impact of surface pre-reacted glass-ionomer nanoparticles on ion dynamics and the physio-mechanical properties of denture base resin	8
Assessment of obstructive sleep apnea risk in different types of cleft lip and palate	8
Impact of radiotherapy in chemical composition and mechanical properties of human cervical dentin: an in vitro study	8
Interleukin-17 plays a role in dental pulp inflammation mediated by zoledronic acid: a mechanism unrelated to the Th17 immune response?	8
Metabolic effect of low fluoride levels in the islets of NOD mice: integrative morphological, immunohistochemical, and proteomic analyses	8
Effect of genetic polymorphisms rs2301113 and rs2057482 in the expression of HIF-1α protein in periodontal ligament fibroblasts subjected to compressive force	7
Influence of repositioning guides’ color and usage on precision in tooth color measurement with a clinical spectrophotometer	7
Antimicrobial photocatalysis using bio-hydrothermally synthesized Zinc oxide nanoparticles in the management of periodontitis: a prospective split-mouth, double-blind, randomized, controlled clinical	7
Evaluation of the effect of Matricaria recutita monotherapy or in combination with photodynamic therapy on tissue repair in the dorsum of the tongue of rats*	7
Nasopalatine duct cyst: a multicenter retrospective study of 63 cases and an integrative review of the clinical, imaginological and histopathological aspects	7
Trueness comparison of various intraoral scanners and hybrid workflow for ceramic restoration	6
The effect of calcium hydroxide and double antibiotic paste on radiographic outcomes and periapical MMP-8 levels in regenerative endodontic procedures: a randomized clinical trial	6
Integrated correlation analysis of the thickness of buccal bone and gingiva of maxillary incisors	6
Oral microbiome patterns of dental caries in Kazakhstani adolescents	6
Panax notoginseng saponins alleviate alveolar bone loss and reprogram macrophages in diabetic periodontitis rats	6
Evaluation of surface roughness, wettability and adhesion of multispecies biofilm on 3D-printed resins for the base and teeth of complete dentures	6
Phyllanthus emblica fruit extract alleviates halitosis and reduces the inflammatory response to oral bacteria	6
Diversity of Streptococcus mutans serotypes isolated from dental plaque of Brazilian patients with a history of acute myocardial infarction	5
An engineering perspective of ceramics applied in dental reconstructions	5
Chitosan nanoparticles suspension can minimize enamel loss after in vitro erosive challenge	5
Histological evaluation of the surgical margins of oral soft tissue incisions using a dual-wavelength diode laser and an Er, Cr:YSGG laser; an ex vivo study	5
Human umbilical cord mesenchymal stem cells accelerate and increase implant osseointegration in diabetic rats	5
Can the combination of proanthocyanidin and vitamin E or palm oil effectively protect enamel against in vitro erosive and abrasive challenges?	5
Evaluation of volumetric wear loss and pain scores of the digitally and conventionally manufactured occlusal splints for individuals with sleep bruxism	5
Sleep recovery ameliorates submandibular salivary gland inflammation associated with paradoxical sleep deprivation in male Wistar rats	5
Suppressing STAT3 activation impairs bone formation during maxillary expansion and relapse	5
Effects of Thai propolis mixed in mineral trioxide aggregate on matrix metalloproteinase-2 expression and activity in inflamed human dental pulp cells	5
The effect of Stage I-II periodontitis on the mechanical, structural, and biological properties of leukocyte and platelet-rich fibrin	5
Analysis of peri-implant bone tissue between hydrophilic and rough implant surfaces in spontaneously hypertensive rats treated with losartan	5
Stem cell-derived exosomes from human exfoliated deciduous teeth promote angiogenesis in hyperglycemic-induced human umbilical vein endothelial cells	5
Evaluation of the impact of alveolar bone graft surgery on the nasal cavity of individuals with cleft lip and palate	5
The effect of injectable platelet-rich fibrin and platelet-rich fibrin in regenerative endodontics: a comparative in vitro study	4
ERRATUM	4
Acquired pellicle engineering: a fascinating approach to prevent demineralization	4
Survival rate of the Hall technique compared with resin composite restoration in multi-surface cavities in primary teeth: a 1-year randomized clinical trial	4
Vagus nerve stimulation alleviates alveolar bone loss and inflammation in ligature-induced periodontitis rat model	4
Classification success of salivary interleukin-1β in periodontitis grading with artificial intelligence models: a cross-sectional observational study	4
Comparative analysis of connective tissue graft versus ozone-enriched platelet-rich fibrin in the treatment of Cairo class I gingival recessions: a randomized, double-blind, controlled clinical trial	4

Bleaching as a complement to fluoride-enhanced remineralization or resin infiltration in masking white spot lesions	4
Determination of sexual dimorphism with CBCT images of the frontal sinus using a predictive formula and an artificial neural network	4
Cognitive and Orofacial Intersections: prevalence of temporomandibular disorders and bruxism in individuals with symptoms of attention deficit hyperactivity disorder	4
Association between dental fracture and amalgam restoration: a case-control study	4
Can composite packaging and selective enamel etching affect the clinical behavior of bulk-fill composite resin in posterior restorations? 24-month results of a randomized clinical trial	4
Salivary protein candidates for biomarkers of oral disorders in people with a crack cocaine use disorder	4
Accuracy of two methods to detect the presence of halitosis: the volatile sulfur compounds concentration in the mouth air and the information from a close person	4
Association of rs142548867 (EEFSEC) and periodontitis Grade C in a young Brazilian population	4
The effects of Stemregen® host modulation therapy on experimentally induced apical periodontitis in rats*	4
M1 and M2 macrophages markers are alternately expressed during periapical lesion development	4
Implications of the health information pollution for society, health professionals, and science	3
Diagnostic potential of Type VII Collagen during oral carcinogenesis	3
Cytotoxicity of dilutions of bioceramic materials in stem cells of human exfoliated deciduous teeth	3
Factors influencing the response to periodontal therapy in patients with diabetes: post hoc analysis of a randomized clinical trial using machine learning	3
Degradable hydrogel fibers encapsulate and deliver metformin and periodontal ligament stem cells for dental and periodontal regeneration	3
Association between circulating inflammatory proteins and temporomandibular disorders: insight from a two-sample Mendelian randomization analysis	3
Parkinson's disease and Porphyromonas gingivalis levels: a case-control study	3
The impact of the COVID-19 pandemic on dental trauma attendance: a systematic review and meta-analysis	3
Effect of anaerobic or/and microaerophilic atmosphere on microcosm biofilm formation and tooth demineralization	3
Performance of obturation techniques in anatomical irregularities located at different thirds of the root canal system	3
Effects of adding electro-massage to manual therapy for the treatment of individuals with myofascial temporomandibular pain: a randomized controlled trial	3
A randomized prospective clinical study evaluating the effectiveness of the Beautibond Xtreme adhesive system using different bonding techniques in class I and II restorations: one-year results	3
Standardized Centella asiatica extract ECa 233 alleviates pain hypersensitivity by modulating P2X3 in trigeminal neuropathic pain	3
Impact of non surgical periodontal therapy on glycemic control in individuals with type 2 diabetes mellitus and periodontitis	3
Genetic variants of EBI3, tumor Epstein-Barr virus, and human cytomegalovirus status in HPV-negative oral cancer	3
Estrogen versus bone marrow mesenchymal stromal cells in the regeneration of the parotid gland in ovariectomized rats	3
Effects of a low-dose combination therapy of zoledronate and dexamethasone on post-tooth extraction socket healing: a pre-clinical study in mice	3
Synergistic anti-cancer effects of metformin and cisplatin on YD-9 oral squamous carcinoma cells via AMPK pathway	3
Survival of severely compromised endodontically treated teeth restored with or without a fiber glass post	3
TIPE2 regulates periodontal inflammation by inhibiting NF-κB p65 phosphorylation	3
Effect of ozone oil and non-surgical periodontal treatment in patients with type 2 diabetes. In-vivo and in-vitro studies with fibroblasts and Candida albicans	3
ERRATUM	3
Exploring polymorphisms in genes encoding growth factors associated with non-syndromic cleft lip with or without cleft palate and tooth agenesis	3
Is there an association between molar-incisor hypomineralization and carious lesions in seven to ten-year-old Brazilian schoolchildren? A cross-sectional study	3
Influence of manufacturing methods and use of CoCr-based abutments on vertical and horizontal marginal fit and torque loss in implant-supported prostheses	2
Three-dimensional soft tissue comparison in non-growing patients treated for skeletal Class II Division I malocclusion: mandibular advancement surgery vs. Herbst Appliance	2
PI3K/AKT signaling mediate collagen type 1-induced osteogenic differentiation of dental pulp stem cells via focal adhesion mechanism	2
Antioxidant potential of wine polyphenols on hematological indices and apical periodontitis in male rats	2
Assessment of chitosan addition to at-home bleaching gel with and without calcium on the physical properties of tooth enamel	2
Titanium micro-nano textured surface with strontium incorporation improves osseointegration: an in vivo and in vitro study*	2
Intra-familial phenotype variant in hypoplastic amelogenesis imperfecta under a complex genetic component: a family report, whole-exome sequencing, and literature review	2
Can angiotensin II affect the inflammatory response of human dental pulp cells in vitro?	2
Can high pain intensity and catastrophizing interfere with the cognitive performance of women with chronic pain related TMD? A cross-sectional study	2
A comparative study of three liquid platelet concentrates on human primary osteoblast activity: an in vitro study	2
Lipid nanocarrier containing eugenol for denture hygiene: evaluation of efficacy against Candida biofilms	2
Physicochemical properties of flowable composites using isobornyl methacrylate as diluent monomer	2
DNMT3A transcriptionally downregulated by KLF5 alleviates LPS-induced inflammatory response and promotes osteogenic differentiation in hPDLSCs	2
Effects of bromelain, melatonin, and thymoquinone on neutrophil extracellular trap formation and macrophage polarization in experimental periodontitis	2
Bleaching gel volume influences hydrogen peroxide diffusion, inflammation, and the presence of nitric oxide in the pulp tissue: in vitro and in vivo model	2
Chitosan microparticles loaded with essential oils inhibit duo-biofilms of Candida albicans and Streptococcus mutans	2
ERRATUM	2
The dynamin inhibitor, dynasore, prevents zoledronate-induced viability loss in human gingival fibroblasts by partially blocking zoledronate uptake and inhibiting endosomal acidification	2
Fish: a new xenograft source for maxillary sinus lifting	2
Biofilm dysbiosis and caries activity: a surface or an individual issue?	2
Effect of submucosal cryotherapy compared with steroids and NSAIDs injections on Substance P and Interleukin 6 pulpal release in experimentally induced pulpal inflammation in rabbits	2
Chronic exposure to lipopolysaccharides as an in vitro model to simulate the impaired odontogenic potential of dental pulp cells under pulpitis conditions	2
ERRATUM	2
ERRATUM	2
Influence of daily usage times on patients’ compliance during at-home bleaching: a randomized clinical trial	2
The effect of dexmedetomidine-ketamine combination versus dexmedetomidine on behavior of uncooperative pediatric dental patients: a randomized controlled clinical trial	2
Test-retest reliability of the isometric contraction test (IC test) of the masticatory muscles in subjects with and without temporomandibular muscle disorders	2