OOIR: Observatory of International Research

Papers

(The TQCC of Protein & Cell is 9. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-08-01 to 2025-08-01.)

Article	Citations
“Always learn today, stand ready to act tomorrow”—Po Tien: A pioneer of Virology in China	164
Pan Shuh: the founding figure of modern Chinese psychology	157
Anthrax lethal toxin and tumor necrosis factor-α synergize on intestinal epithelia to induce mouse death	87
ARID1A IDR targets EWS-FLI1 condensates and finetunes chromatin remodeling	74
JMJD1C forms condensate to facilitate a RUNX1-dependent gene expression program shared by multiple types of AML cells	71
An improved method for the detection of double-stranded RNA suitable for quality control of mRNA vaccines	61
Architecture of severe fever with thrombocytopenia syndrome virus	61
Cancer biology deciphered by single-cell transcriptomic sequencing	60
Microbiome research outlook: past, present, and future	58
Endoplasmic reticulum membrane remodeling by targeting reticulon-4 induces pyroptosis to facilitate antitumor immune	52
DCK confers sensitivity of DCTD-positive cancer cells to oxidized methylcytidines	47
One step, two functions: the mechanism of the ABCH class of transporter serving barrier construction and detoxification in insects	46
Spatially-resolved expression landscape and gene-regulatory network of human gastric corpus epithelium	46
Gene print-based cell subtypes annotation of human disease across heterogeneous datasets with gPRINT	42
Gut microbial methionine impacts circadian clock gene expression and reactive oxygen species level in host gastrointestinal tract	38
Withdrawn as Duplicate: Remembering the Scholar Ding Ying: The Father of Chinese Rice-Farming Science	37
Single-nucleus transcriptomics reveals a gatekeeper role for FOXP1 in primate cardiac aging	37
Unfolding HBx for an epigenetic switch of HBV cccDNA minichromosome	32
Strategies for generating mouse model resources of human disease	31
An ultrapotent pan-β-coronavirus lineage B (β-CoV-B) neutralizing antibody locks the receptor-binding domain in closed conformation by targeting its conserved epitope	31
Cryo-EM structures of Nipah virus polymerase complex reveal highly varied interactions between L and P proteins among paramyxoviruses	30
Dynamin 1-mediated endocytic recycling of glycosylated N-cadherin sustains the plastic mesenchymal state to promote ovarian cancer metastasis	30
Mutations in the SARS-CoV-2 spike receptor binding domain and their delicate balance between ACE2 affinity and antibody evasion	28
Inheritance and advancement in biochemistry: the pioneering research of Szu-Chih Liu	28
An orally-available monovalent SMAC mimetic compound as a broad-spectrum antiviral	27

Immune rebalancing at the maternal-fetal interface of maternal SARS-CoV-2 infection during early pregnancy	26
A hnRNPA2B1 agonist effectively inhibits HBV and SARS-CoV-2 omicronin vivo	24
A long non-coding RNA LncSync regulates mouse cardiomyocyte homeostasis and cardiac hypertrophy through coordination of miRNA actions	23
Pasteurized Akkermansia muciniphila promotes GP2 expression in microfold cells and facilitates Salmonella infection	23
Correction to: Genome-wide CRISPR screen identifies synthetic lethality between DOCK1 inhibition and metformin in liver cancer	22
Correction to: SIRT7 antagonizes human stem cell aging as a heterochromatin stabilizer	22
A tribute to Professor Yong Zhao	22
Long-term in vivo chimeric cells tracking in non-human primate	21
Oxidative phosphorylation safeguards pluripotency via UDP-N-acetylglucosamine	20
High-throughput screening of SARS-CoV-2 main and papain-like protease inhibitors	20
Adenosine-to-inosine RNA editing in cancer: molecular mechanisms and downstream targets	19
Radiation injury and gut microbiota-based treatment	17
Advances in gene and cellular therapeutic approaches for Huntington’s disease	17
Hunting out the repeat expansion in Huntington’s pigs	16
Modeling hepatoblastoma development with human fetal liver organoids reveals YAP1 activation is sufficient for tumorigenesis	16
Microbial sensing in the intestine	16
SMURF1: a promising target for colon cancer therapy	16
Proteomic analysis of ferroptosis pathways reveals a role of CEPT1 in suppressing ferroptosis	16
Endosomal catabolism of phosphatidylinositol 4,5-bisphosphate is fundamental in building resilience against pathogens	15
Correction to: Adenosine-to-inosine RNA editing in cancer: molecular mechanisms and downstream targets	15
Single transmembrane GPCR modulating proteins: neither single nor simple	15
Systematicidentification of CRISPR off-target effects by CROss-seq	14
Glutamine signaling specifically activates c-Myc and Mcl-1 to Facilitate cancer cell proliferation and survival	14
Secreted proteins in treating metabolic dysfunction-associated steatotic liver disease: from bench towards bedside	14
The microbiota–gut–brain axis and neurodevelopmental disorders	13
Aberrant outputs of cerebellar nuclei and targeted rescue of social deficits in an autism mouse model	12
Synergistic innovation in organ-on-a-chip and organoid technologies: Reshaping the future of disease modeling, drug development and precision medicine	12
Correction to: The nucleocapsid protein of rice stripe virus in cell nuclei of vector insect regulates viral replication	12
Single-cell profiling reveals a potent role of quercetin in promoting hair regeneration	12
Boundless love: a German Professor Uli Schwarz in China	12
Sung Shu Chien: The founder of modern Chinese botany	11
Systematic characterization of full-length RNA isoforms in human colorectal cancer at single-cell resolution	11
Tanjun Tong: a pioneer of cellular senescence and aging mechanism research in China	11
Structural studies promote vaccine development: lessons from African swine fever virus	11
Syn3, a newly developed cyclic peptide and BDNF signaling enhancer, ameliorates retinal ganglion cell degeneration in diabetic retinopathy	11
Single-nucleus transcriptomics uncovers a geroprotective role of YAP in primate gingival aging	11
Degeneration Directory: a multi-omics web resource for degenerative diseases	11
PINK1 kinase dysfunction triggers neurodegeneration in the primate brain without impacting mitochondrial homeostasis	10
Join the club: ORP8 is a lipophagy receptor	10
The chordata olfactory receptor database	10
Virological research history in China: a century of profiling virologists’ contributions and virological innovations	10
Governing glutaminolysis by regulation of glutaminase succinylation	10
Epigenetic integrity of paternal imprints enhances the developmental potential of androgenetic haploid embryonic stem cells	10
Human ESC-derived vascular cells promote vascular regeneration in a HIF-1α dependent manner	9
Single-nucleus profiling unveils a geroprotective role of the FOXO3 in primate skeletal muscle aging	9
A molecular brake that modulates spliceosome pausing at detained introns contributes to neurodegeneration	9
mTORC2/RICTOR exerts differential levels of metabolic control in human embryonic, mesenchymal and neural stem cells	9