OOIR: Observatory of International Research

Papers

(The TQCC of Protein & Cell is 8. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-11-01 to 2025-11-01.)

Article	Citations
Withdrawn as Duplicate: Remembering the Scholar Ding Ying: The Father of Chinese Rice-Farming Science	204
Gene print-based cell subtypes annotation of human disease across heterogeneous datasets with gPRINT	99
Pan Shuh: the founding figure of modern Chinese psychology	96
Unfolding HBx for an epigenetic switch of HBV cccDNA minichromosome	91
Single-nucleus transcriptomics reveals a gatekeeper role for FOXP1 in primate cardiac aging	84
JMJD1C forms condensate to facilitate a RUNX1-dependent gene expression program shared by multiple types of AML cells	74
An improved method for the detection of double-stranded RNA suitable for quality control of mRNA vaccines	53
DCK confers sensitivity of DCTD-positive cancer cells to oxidized methylcytidines	51
Spatially-resolved expression landscape and gene-regulatory network of human gastric corpus epithelium	49
Anthrax lethal toxin and tumor necrosis factor-α synergize on intestinal epithelia to induce mouse death	46
Endoplasmic reticulum membrane remodeling by targeting reticulon-4 induces pyroptosis to facilitate antitumor immune	41
Gut microbial methionine impacts circadian clock gene expression and reactive oxygen species level in host gastrointestinal tract	40
ARID1A IDR targets EWS-FLI1 condensates and finetunes chromatin remodeling	37
Architecture of severe fever with thrombocytopenia syndrome virus	37
DHA, a potentially therapeutic lipid for myocardial infarction	36
Microbiome research outlook: past, present, and future	33
One step, two functions: the mechanism of the ABCH class of transporter serving barrier construction and detoxification in insects	33
Inheritance and advancement in biochemistry: the pioneering research of Szu-Chih Liu	29
Dynamin 1-mediated endocytic recycling of glycosylated N-cadherin sustains the plastic mesenchymal state to promote ovarian cancer metastasis	28
Efficient CRISPR-based gene activation using combinatorial human transcription activation domains	27
Strategies for generating mouse model resources of human disease	26
3D chromatin dynamics in cellular neuroendocrine transformation	25
Cryo-EM structures of Nipah virus polymerase complex reveal highly varied interactions between L and P proteins among paramyxoviruses	24
A single-cell transcriptomic landscape characterizes the endocrine system aging in the mouse	23
Correction to: Genome-wide CRISPR screen identifies synthetic lethality between DOCK1 inhibition and metformin in liver cancer	22

A long non-coding RNA LncSync regulates mouse cardiomyocyte homeostasis and cardiac hypertrophy through coordination of miRNA actions	22
Mutations in the SARS-CoV-2 spike receptor binding domain and their delicate balance between ACE2 affinity and antibody evasion	22
Immune rebalancing at the maternal-fetal interface of maternal SARS-CoV-2 infection during early pregnancy	20
An orally-available monovalent SMAC mimetic compound as a broad-spectrum antiviral	20
Pasteurized Akkermansia muciniphila promotes GP2 expression in microfold cells and facilitates Salmonella infection	20
A hnRNPA2B1 agonist effectively inhibits HBV and SARS-CoV-2 omicronin vivo	20
Correction to: SIRT7 antagonizes human stem cell aging as a heterochromatin stabilizer	19
High-throughput screening of SARS-CoV-2 main and papain-like protease inhibitors	18
Proteomic analysis of ferroptosis pathways reveals a role of CEPT1 in suppressing ferroptosis	18
Long-term in vivo chimeric cells tracking in non-human primate	18
Tuning the Hsp70 chaperone cycle: emerging roles of GrpE-like NEFs in proteostasis and organelle function	18
Oxidative phosphorylation safeguards pluripotency via UDP-N-acetylglucosamine	18
Advances in gene and cellular therapeutic approaches for Huntington’s disease	18
Radiation injury and gut microbiota-based treatment	17
Accumulation of newly synthesized docosahexaenoic acid plays an essential role in heart regeneration	17
Microbial sensing in the intestine	16
Adenosine-to-inosine RNA editing in cancer: molecular mechanisms and downstream targets	16
Hunting out the repeat expansion in Huntington’s pigs	16
Secreted proteins in treating metabolic dysfunction-associated steatotic liver disease: from bench towards bedside	15
SMURF1: a promising target for colon cancer therapy	15
Correction to: Adenosine-to-inosine RNA editing in cancer: molecular mechanisms and downstream targets	14
Modeling hepatoblastoma development with human fetal liver organoids reveals YAP1 activation is sufficient for tumorigenesis	14
Systematicidentification of CRISPR off-target effects by CROss-seq	14
Endosomal catabolism of phosphatidylinositol 4,5-bisphosphate is fundamental in building resilience against pathogens	14
Glutamine signaling specifically activates c-Myc and Mcl-1 to facilitate cancer cell proliferation and survival	13
Single transmembrane GPCR modulating proteins: neither single nor simple	13
Oncogenic role of the SLC7A13-SLC3A1 cystine transporter in human luminal breast cancer and its cryo-EM structure	12
Boundless love: a German Professor Uli Schwarz in China	12
Synergistic innovation in organ-on-a-chip and organoid technologies: reshaping the future of disease modeling, drug development, and precision medicine	12
The microbiota–gut–brain axis and neurodevelopmental disorders	12
Single-cell profiling reveals a potent role of quercetin in promoting hair regeneration	11
Systematic characterization of full-length RNA isoforms in human colorectal cancer at single-cell resolution	11
Single-nucleus transcriptomics uncovers a geroprotective role of YAP in primate gingival aging	10
Tanjun Tong: a pioneer of cellular senescence and aging mechanism research in China	10
Correction to: Endothelial-to-Osteoblast Conversion maintains bone homeostasis through Kindlin-2/Piezo1/TGFβ/Runx2 axis	10
Structural studies promote vaccine development: lessons from African swine fever virus	10
Sung Shu Chien: The founder of modern Chinese botany	10
Aberrant outputs of cerebellar nuclei and targeted rescue of social deficits in an autism mouse model	10
Degeneration Directory: a multi-omics web resource for degenerative diseases	10
Syn3, a newly developed cyclic peptide and BDNF signaling enhancer, ameliorates retinal ganglion cell degeneration in diabetic retinopathy	10
Virological research history in China: a century of profiling virologists’ contributions and virological innovations	9
Governing glutaminolysis by regulation of glutaminase succinylation	9
Epigenetic integrity of paternal imprints enhances the developmental potential of androgenetic haploid embryonic stem cells	9
The chordata olfactory receptor database	8
PINK1 kinase dysfunction triggers neurodegeneration in the primate brain without impacting mitochondrial homeostasis	8
mTORC2/RICTOR exerts differential levels of metabolic control in human embryonic, mesenchymal and neural stem cells	8
Human ESC-derived vascular cells promote vascular regeneration in a HIF-1α dependent manner	8
Cryo-EM structure of human κ-opioid receptor-Gi complex bound to an endogenous agonist dynorphin A	8
Join the club: ORP8 is a lipophagy receptor	8
Bardoxolone methyl blocks the efflux of Zn2+ by targeting hZnT1 to inhibit the proliferation and metastasis of cervical cancer	8

A molecular brake that modulates spliceosome pausing at detained introns contributes to neurodegeneration