OOIR: Observatory of International Research

Papers

(The TQCC of Protein & Cell is 10. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-08-01 to 2026-08-01.)

Article	Citations
Withdrawn as Duplicate: Remembering the Scholar Ding Ying: The Father of Chinese Rice-Farming Science	335
Gene print-based cell subtypes annotation of human disease across heterogeneous datasets with gPRINT	326
Pan Shuh: the founding figure of modern Chinese psychology	189
JMJD1C forms condensate to facilitate a RUNX1-dependent gene expression program shared by multiple types of AML cells	172
Spatially-resolved expression landscape and gene-regulatory network of human gastric corpus epithelium	131
DHA, a potentially therapeutic lipid for myocardial infarction	124
Unfolding HBx for an epigenetic switch of HBV cccDNA minichromosome	97
Anthrax lethal toxin and tumor necrosis factor-α synergize on intestinal epithelia to induce mouse death	81
ARID1A IDR targets EWS-FLI1 condensates and finetunes chromatin remodeling	76
An improved method for the detection of double-stranded RNA suitable for quality control of mRNA vaccines	74
Single-nucleus transcriptomics reveals a gatekeeper role for FOXP1 in primate cardiac aging	66
Recent progresses in cancer multidrug resistance and therapeutic options associated with protein damage response	66
Microbiome research outlook: past, present, and future	58
Topology-Driven Activation of the GLP-1 Receptor Promotes Adipose Tissue Browning	57
Correction to: Metformin inhibits pancreatic cancer metastasis caused by SMAD4 deficiency and consequent HNF4G upregulation	55
Architecture of severe fever with thrombocytopenia syndrome virus	54
Endoplasmic reticulum membrane remodeling by targeting reticulon-4 induces pyroptosis to facilitate antitumor immune	51
Astragalus membranaceus ameliorates endometrial aging and restores receptivity by enhancing mitochondrial function in stromal and epithelial cells	50
One step, two functions: the mechanism of the ABCH class of transporter serving barrier construction and detoxification in insects	41
Inheritance and advancement in biochemistry: the pioneering research of Szu-Chih Liu	40
Efficient clustered, regularly interspaced short palindromic repeats-based gene activation using combinatorial human transcription activation domains	39
Dynamin 1-mediated endocytic recycling of glycosylated N-cadherin sustains the plastic mesenchymal state to promote ovarian cancer metastasis	38
Strategies for generating mouse model resources of human disease	37
A single-cell transcriptomic landscape characterizes the endocrine system aging in the mouse	36
3D chromatin dynamics in cellular neuroendocrine transformation	35

NSUN2‑mediated epitranscriptomic and ubiquitin modulation of Nipah virus matrix protein reveals a dual-targeting antiviral strategy	34
Cryo-EM structures of Nipah virus polymerase complex reveal highly varied interactions between L and P proteins among paramyxoviruses	34
Shared CRISPR arrays underpin type I-A/I-B coexistence	33
Pasteurized Akkermansia muciniphila promotes GP2 expression in microfold cells and facilitates Salmonella infection	32
Mutations in the SARS-CoV-2 spike receptor binding domain and their delicate balance between ACE2 affinity and antibody evasion	32
Restoring the FOXO1 geroprotective pathway via seno-resistant mesenchymal progenitor cells alleviates primate epididymal aging	31
Correction to: Genome-wide CRISPR screen identifies synthetic lethality between DOCK1 inhibition and metformin in liver cancer	31
Immune rebalancing at the maternal-fetal interface of maternal SARS-CoV-2 infection during early pregnancy	30
An orally-available monovalent SMAC mimetic compound as a broad-spectrum antiviral	30
Tuning the Hsp70 chaperone cycle: emerging roles of GrpE-like nucleotide exchange factors in proteostasis and organelle function	29
Long-term in vivo chimeric cells tracking in non-human primate	29
Correction to: SIRT7 antagonizes human stem cell aging as a heterochromatin stabilizer	29
High-throughput screening of SARS-CoV-2 main and papain-like protease inhibitors	29
Primate abnormal spindle-like microcephaly-associated knockout causes severe microcephaly and oligodendrocyte loss in the brain	28
Oxidative phosphorylation safeguards pluripotency via UDP-N-acetylglucosamine	27
Tumor cell GPX4 dictates triacylglycerol metabolism for ferroptosis susceptibility and immune evasion of NSCLC	27
Accumulation of newly synthesized docosahexaenoic acid plays an essential role in heart regeneration	26
What we can learn from hibernators and other adapted animals about organ transplantation: mechanisms of cold resistance and enhanced regeneration	25
Advances in gene and cellular therapeutic approaches for Huntington’s disease	24
Adenosine-to-inosine RNA editing in cancer: molecular mechanisms and downstream targets	24
Microbial sensing in the intestine	23
Radiation injury and gut microbiota-based treatment	22
Proteomic analysis of ferroptosis pathways reveals a role of CEPT1 in suppressing ferroptosis	22
Endosomal catabolism of phosphatidylinositol 4,5-bisphosphate is fundamental in building resilience against pathogens	21
SMURF1: a promising target for colon cancer therapy	21
Single transmembrane GPCR modulating proteins: neither single nor simple	20
Secreted proteins in treating metabolic dysfunction-associated steatotic liver disease: from bench towards bedside	19
Correction to: Adenosine-to-inosine RNA editing in cancer: molecular mechanisms and downstream targets	19
Hunting out the repeat expansion in Huntington’s pigs	19
The microbiota–gut–brain axis and neurodevelopmental disorders	18
Glutamine signaling specifically activates c-Myc and Mcl-1 to facilitate cancer cell proliferation and survival	18
MANF is essential for astrocyte survival in the monkey brain	18
Systematic characterization of full-length RNA isoforms in human colorectal cancer at single-cell resolution	17
Aberrant outputs of cerebellar nuclei and targeted rescue of social deficits in an autism mouse model	17
Boundless love: a German Professor Uli Schwarz in China	17
Single-cell profiling reveals a potent role of quercetin in promoting hair regeneration	17
Oncogenic role of the SLC7A13-SLC3A1 cystine transporter in human luminal breast cancer and its cryo-EM structure	16
Correction to: DHA, a potentially therapeutic lipid for myocardial infarction	16
Synergistic innovation in organ-on-a-chip and organoid technologies: reshaping the future of disease modeling, drug development, and precision medicine	16
Degeneration Directory: a multi-omics web resource for degenerative diseases	15
Sung Shu Chien: The founder of modern Chinese botany	15
Syn3, a newly developed cyclic peptide and BDNF signaling enhancer, ameliorates retinal ganglion cell degeneration in diabetic retinopathy	14
Correction to: Endothelial-to-Osteoblast Conversion maintains bone homeostasis through Kindlin-2/Piezo1/TGFβ/Runx2 axis	14
Single-nucleus transcriptomics uncovers a geroprotective role of YAP in primate gingival aging	13
The chordata olfactory receptor database	13
Tanjun Tong: a pioneer of cellular senescence and aging mechanism research in China	13
Structural studies promote vaccine development: lessons from African swine fever virus	13
Virological research history in China: a century of profiling virologists’ contributions and virological innovations	13
Join the club: ORP8 is a lipophagy receptor	12
Human ESC-derived vascular cells promote vascular regeneration in a HIF-1α dependent manner	12

Cryo-EM structure of human κ-opioid receptor-Gi complex bound to an endogenous agonist dynorphin A	11
MMP-9 regulates disulphide isomerase activity of TGM2 to enhance fusion glycoprotein-mediated syncytium formation of respiratory syncytial virus	11
The role of parkin in monkey	11
RNA helicase MTR4 drives tumorigenesis of nasopharyngeal carcinoma by regulating the expression of key cell cycle genes	11
A molecular brake that modulates spliceosome pausing at detained introns contributes to neurodegeneration	11
Whole-exome sequencing identifies ECPAS as a novel potentially pathogenic gene in multiple hereditary families with nonsyndromic orofacial cleft	11
Platelet RNA signature independently predicts ovarian cancer prognosis by deep learning neural network model	10
Kechun Lin: a pioneer of biophysics explorations in China	10
Single-nucleus profiling unveils a geroprotective role of the FOXO3 in primate skeletal muscle aging	10
Ergothioneine and its congeners: anti-ageing mechanisms and pharmacophore biosynthesis	10
Bardoxolone methyl blocks the efflux of Zn2+ by targeting hZnT1 to inhibit the proliferation and metastasis of cervical cancer	10
Platelet RNA enables accurate detection of ovarian cancer: an intercontinental, biomarker identification study	10
A yolk sac-derived hepatic γδ T cell subpopulation develops in a hematopoietic stem cell- and thymus-independent manner	10
Structural basis of INTAC-regulated transcription	10
Gut dysbiosis impairs intestinal renewal and lipid absorption in Scarb2 deficiency-associated neurodegeneration	10