OOIR: Observatory of International Research

Papers

(The TQCC of Protein & Cell is 8. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-05-01 to 2025-05-01.)

Article	Citations
“Always learn today, stand ready to act tomorrow”—Po Tien: A pioneer of Virology in China	156
Gut microbial methionine impacts circadian clock gene expression and reactive oxygen species level in host gastrointestinal tract	112
An improved method for the detection of double-stranded RNA suitable for quality control of mRNA vaccines	109
DCK confers sensitivity of DCTD-positive cancer cells to oxidized methylcytidines	83
Pan Shuh: the founding figure of modern Chinese psychology	77
Anthrax lethal toxin and tumor necrosis factor-α synergize on intestinal epithelia to induce mouse death	62
Unfolding HBx for an epigenetic switch of HBV cccDNA minichromosome	52
Architecture of severe fever with thrombocytopenia syndrome virus	51
Gene print-based cell subtypes annotation of human disease across heterogeneous datasets with gPRINT	51
Remembering the Scholar Ding Ying: The Father of Chinese Rice-Farming Science	45
Single-nucleus transcriptomics reveals a gatekeeper role for FOXP1 in primate cardiac aging	44
ARID1A IDR targets EWS-FLI1 condensates and finetunes chromatin remodeling	41
Spatially-resolved expression landscape and gene-regulatory network of human gastric corpus epithelium	40
Endoplasmic reticulum membrane remodeling by targeting reticulon-4 induces pyroptosis to facilitate antitumor immune	39
JMJD1C forms condensate to facilitate a RUNX1-dependent gene expression program shared by multiple types of AML cells	37
Cancer biology deciphered by single-cell transcriptomic sequencing	35
Microbiome research outlook: past, present, and future	33
Dynamin 1-mediated endocytic recycling of glycosylated N-cadherin sustains the plastic mesenchymal state to promote ovarian cancer metastasis	31
An ultrapotent pan-β-coronavirus lineage B (β-CoV-B) neutralizing antibody locks the receptor-binding domain in closed conformation by targeting its conserved epitope	27
Cryo-EM structures of Nipah virus polymerase complex reveal highly varied interactions between L and P proteins among paramyxoviruses	27
Strategies for generating mouse model resources of human disease	25
Immune rebalancing at the maternal-fetal interface of maternal SARS-CoV-2 infection during early pregnancy	23
A hnRNPA2B1 agonist effectively inhibits HBV and SARS-CoV-2 omicronin vivo	23
Mutations in the SARS-CoV-2 spike receptor binding domain and their delicate balance between ACE2 affinity and antibody evasion	23
A long non-coding RNA LncSync regulates mouse cardiomyocyte homeostasis and cardiac hypertrophy through coordination of miRNA actions	22

Pasteurized Akkermansia muciniphila promotes GP2 expression in microfold cells and facilitates Salmonella infection	22
An orally-available monovalent SMAC mimetic compound as a broad-spectrum antiviral	22
Correction to: SIRT7 antagonizes human stem cell aging as a heterochromatin stabilizer	21
A tribute to Professor Yong Zhao	21
High-throughput screening of SARS-CoV-2 main and papain-like protease inhibitors	21
Oxidative phosphorylation safeguards pluripotency via UDP-N-acetylglucosamine	21
RNA m6A meets transposable elements and chromatin	18
Long-term in vivo chimeric cells tracking in non-human primate	18
Radiation injury and gut microbiota-based treatment	17
Advances in gene and cellular therapeutic approaches for Huntington’s disease	16
Adenosine-to-inosine RNA editing in cancer: molecular mechanisms and downstream targets	16
Endosomal catabolism of phosphatidylinositol 4,5-bisphosphate is fundamental in building resilience against pathogens	15
Proteomic analysis of ferroptosis pathways reveals a role of CEPT1 in suppressing ferroptosis	15
Microbial sensing in the intestine	15
Hunting out the repeat expansion in Huntington’s pigs	14
Modeling hepatoblastoma development with human fetal liver organoids reveals YAP1 activation is sufficient for tumorigenesis	14
Systematicidentification of CRISPR off-target effects by CROss-seq	13
Correction to: Adenosine-to-inosine RNA editing in cancer: molecular mechanisms and downstream targets	13
Secreted proteins in treating metabolic-dysfunction associated steatotic liver disease: from bench towards bedside	13
SMURF1: a promising target for colon cancer therapy	13
Boundless love: a German Professor Uli Schwarz in China	12
The microbiota–gut–brain axis and neurodevelopmental disorders	12
Single transmembrane GPCR modulating proteins: neither single nor simple	12
Degeneration Directory: a multi-omics web resource for degenerative diseases	11
Sung Shu Chien: The founder of modern Chinese botany	11
Syn3, a newly developed cyclic peptide and BDNF signaling enhancer, ameliorates retinal ganglion cell degeneration in diabetic retinopathy	11
Correction to: The nucleocapsid protein of rice stripe virus in cell nuclei of vector insect regulates viral replication	11
Aberrant outputs of cerebellar nuclei and targeted rescue of social deficits in an autism mouse model	11
Tanjun Tong: a pioneer of cellular senescence and aging mechanism research in China	11
Single-cell profiling reveals a potent role of quercetin in promoting hair regeneration	11
mTORC2/RICTOR exerts differential levels of metabolic control in human embryonic, mesenchymal and neural stem cells	10
Single-nucleus transcriptomics uncovers a geroprotective role of YAP in primate gingival aging	10
Epigenetic integrity of paternal imprints enhances the developmental potential of androgenetic haploid embryonic stem cells	10
A molecular brake that modulates spliceosome pausing at detained introns contributes to neurodegeneration	10
The chordata olfactory receptor database	9
Virological research history in China: a century of profiling virologists’ contributions and virological innovations	9
Human ESC-derived vascular cells promote vascular regeneration in a HIF-1α dependent manner	9
Join the club: ORP8 is a lipophagy receptor	9
PINK1 kinase dysfunction triggers neurodegeneration in the primate brain without impacting mitochondrial homeostasis	8
Governing glutaminolysis by regulation of glutaminase succinylation	8
RNA helicase MTR4 drives tumorigenesis of nasopharyngeal carcinoma by regulating the expression of key cell cycle genes	8
Cryo-EM structure of human κ-opioid receptor-Gi complex bound to an endogenous agonist dynorphin A	8
Gut dysbiosis impairs intestinal renewal and lipid absorption in Scarb2 deficiency-associated neurodegeneration	8
The role of parkin in monkey	8
Whole-exome sequencing identifies ECPAS as a novel potentially pathogenic gene in multiple hereditary families with nonsyndromic orofacial cleft	8
Structural basis of INTAC-regulated transcription	8