OOIR: Observatory of International Research

Papers

(The H4-Index of Protein & Cell is 40. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-04-01 to 2024-04-01.)

Article	Citations
Cystine transporter SLC7A11/xCT in cancer: ferroptosis, nutrient dependency, and cancer therapy	819
A practical guide to amplicon and metagenomic analysis of microbiome data	368
Recapitulation of SARS-CoV-2 infection and cholangiocyte damage with human liver ductal organoids	281
Mapping the epigenetic modifications of DNA and RNA	174
The role of the gut microbiome and its metabolites in metabolic diseases	174
A human circulating immune cell landscape in aging and COVID-19	170
Ferroptosis, radiotherapy, and combination therapeutic strategies	167
Targeting the alternative bile acid synthetic pathway for metabolic diseases	143
The microbiome in inflammatory bowel diseases: from pathogenesis to therapy	131
Crystal structure of SARS-CoV-2 main protease in complex with protease inhibitor PF-07321332	123
Novel and potent inhibitors targeting DHODH are broad-spectrum antivirals against RNA viruses including newly-emerged coronavirus SARS-CoV-2	115
Unexpected guests in the tumor microenvironment: microbiome in cancer	103
Insights into epigenetic patterns in mammalian early embryos	98
High-throughput screening identifies established drugs as SARS-CoV-2 PLpro inhibitors	92
The potential of using blood circular RNA as liquid biopsy biomarker for human diseases	92
Mesenchymal stem cell therapy for acute respiratory distress syndrome: from basic to clinics	91
Nuclear m6A reader YTHDC1 regulates the scaffold function of LINE1 RNA in mouse ESCs and early embryos	82
SIRT7 antagonizes human stem cell aging as a heterochromatin stabilizer	82
New avenues for systematically inferring cell-cell communication: through single-cell transcriptomics data	80
Pioneer of prostate cancer: past, present and the future of FOXA1	78
Mouse-adapted SARS-CoV-2 replicates efficiently in the upper and lower respiratory tract of BALB/c and C57BL/6J mice	74
RIP1-dependent linear and nonlinear recruitments of caspase-8 and RIP3 respectively to necrosome specify distinct cell death outcomes	73
Single-cell analysis reveals bronchoalveolar epithelial dysfunction in COVID-19 patients	70
Role of gut microbiota in identification of novel TCM-derived active metabolites	68
KIF2C: a novel link between Wnt/β-catenin and mTORC1 signaling in the pathogenesis of hepatocellular carcinoma	66

Host metabolism dysregulation and cell tropism identification in human airway and alveolar organoids upon SARS-CoV-2 infection	65
Gut microbes in cardiovascular diseases and their potential therapeutic applications	61
Metformin activates chaperone-mediated autophagy and improves disease pathologies in an Alzheimer disease mouse model	61
BMAL1 regulates mitochondrial fission and mitophagy through mitochondrial protein BNIP3 and is critical in the development of dilated cardiomyopathy	58
The mini player with diverse functions: extracellular vesicles in cell biology, disease, and therapeutics	57
Potentiating CD8+ T cell antitumor activity by inhibiting PCSK9 to promote LDLR-mediated TCR recycling and signaling	57
TRIM35 mediates protection against influenza infection by activating TRAF3 and degrading viral PB2	52
Architecture of the herpesvirus genome-packaging complex and implications for DNA translocation	51
The function and regulation of TET2 in innate immunity and inflammation	49
Gut microbiota alterations are distinct for primary colorectal cancer and hepatocellular carcinoma	48
Lipids and membrane-associated proteins in autophagy	46
Non-enzymatic covalent modifications: a new link between metabolism and epigenetics	45
Single-nucleus transcriptomic landscape of primate hippocampal aging	44
Generation of a Hutchinson–Gilford progeria syndrome monkey model by base editing	43
Live cell imaging and proteomic profiling of endogenous NEAT1 lncRNA by CRISPR/Cas9-mediated knock-in	40
Sirt1 regulates testosterone biosynthesis in Leydig cells via modulating autophagy	40
Dynamic cell transition and immune response landscapes of axolotl limb regeneration revealed by single-cell analysis	40
Biallelic mutations in CDC20 cause female infertility characterized by abnormalities in oocyte maturation and early embryonic development	40