OOIR: Observatory of International Research

Papers

(The median citation count of Virologica Sinica is 7. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-03-01 to 2024-03-01.)

Article	Citations
Understanding SARS-CoV-2-Mediated Inflammatory Responses: From Mechanisms to Potential Therapeutic Tools	512
On the Calculation of TCID50 for Quantitation of Virus Infectivity	156
SARS-Coronavirus-2 Nsp13 Possesses NTPase and RNA Helicase Activities That Can Be Inhibited by Bismuth Salts	137
Development of a Novel Reverse Transcription Loop-Mediated Isothermal Amplification Method for Rapid Detection of SARS-CoV-2	103
A Unique Protease Cleavage Site Predicted in the Spike Protein of the Novel Pneumonia Coronavirus (2019-nCoV) Potentially Related to Viral Transmissibility	94
A DNA Aptamer Based Method for Detection of SARS-CoV-2 Nucleocapsid Protein	94
Current Status and Challenge of Pseudorabies Virus Infection in China	72
Porcine Coronaviruses: Overview of the State of the Art	68
Bacteriophages and Lysins in Biofilm Control	63
African Swine Fever Virus MGF360-12L Inhibits Type I Interferon Production by Blocking the Interaction of Importin α and NF-κB Signaling Pathway	57
Clinical Characteristics of Hospitalized Patients with SARS-CoV-2 and Hepatitis B Virus Co-infection	57
A Comprehensive Review of Animal Models for Coronaviruses: SARS-CoV-2, SARS-CoV, and MERS-CoV	53
Viral and Antibody Kinetics of COVID-19 Patients with Different Disease Severities in Acute and Convalescent Phases: A 6-Month Follow-Up Study	51
African Swine Fever Virus MGF-110-9L-deficient Mutant Has Attenuated Virulence in Pigs	48
Clinical Manifestation and Laboratory Characteristics of SARS-CoV-2 Infection in Pregnant Women	46
Computational Identification of Small Interfering RNA Targets in SARS-CoV-2	41
Mild Cytokine Elevation, Moderate CD4+ T Cell Response and Abundant Antibody Production in Children with COVID-19	41
Griffithsin with A Broad-Spectrum Antiviral Activity by Binding Glycans in Viral Glycoprotein Exhibits Strong Synergistic Effect in Combination with A Pan-Coronavirus Fusion Inhibitor Targeting SARS-C	39
A Comprehensive Review on Human Aichi Virus	38
A Small-Scale Medication of Leflunomide as a Treatment of COVID-19 in an Open-Label Blank-Controlled Clinical Trial	37
The Rapid Assessment and Early Warning Models for COVID-19	32
Long Term Culture of Human Kidney Proximal Tubule Epithelial Cells Maintains Lineage Functions and Serves as an Ex vivo Model for Coronavirus Associated Kidney Injury	31
Serologic Response to SARS-CoV-2 in COVID-19 Patients with Different Severity	30
Metagenomic Profiling of Viruses Associated with Rhipicephalus microplus Ticks in Yunnan Province, China	30
Influenza A Virus (H1N1) Infection Induces Glycolysis to Facilitate Viral Replication	29

Broad Cell Tropism of SADS-CoV In Vitro Implies Its Potential Cross-Species Infection Risk	28
Discrimination of False Negative Results in RT-PCR Detection of SARS-CoV-2 RNAs in Clinical Specimens by Using an Internal Reference	25
Dynamic Changes of Antibodies to SARS-CoV-2 in COVID-19 Patients at Early Stage of Outbreak	25
The Novel PRRSV Strain HBap4-2018 with a Unique Recombinant Pattern Is Highly Pathogenic to Piglets	25
Structure and Function of N-Terminal Zinc Finger Domain of SARS-CoV-2 NSP2	25
A Convenient and Biosafe Replicon with Accessory Genes of SARS-CoV-2 and Its Potential Application in Antiviral Drug Discovery	24
Comparative Antiviral Efficacy of Viral Protease Inhibitors against the Novel SARS-CoV-2 In Vitro	24
Summary of the Detection Kits for SARS-CoV-2 Approved by the National Medical Products Administration of China and Their Application for Diagnosis of COVID-19	23
Long-Term Existence of SARS-CoV-2 in COVID-19 Patients: Host Immunity, Viral Virulence, and Transmissibility	22
Enriched Opportunistic Pathogens Revealed by Metagenomic Sequencing Hint Potential Linkages between Pharyngeal Microbiota and COVID-19	22
Inhibitory Activity of Honeysuckle Extracts against Influenza A Virus In Vitro and In Vivo	22
From Monovalent to Multivalent Vaccines, the Exploration for Potential Preventive Strategies Against Hand, Foot, and Mouth Disease (HFMD)	21
Stability of SARS-CoV-2 on the Surfaces of Three Meats in the Setting That Simulates the Cold Chain Transportation	21
Coping with COVID-19 in Sub-Saharan Africa: What Might the Future Hold?	20
SARS-CoV-2 Serological Survey of Cats in China before and after the Pandemic	20
African Swine Fever Virus Protein E199L Promotes Cell Autophagy through the Interaction of PYCR2	19
Comparison of Clinical and Epidemiological Characteristics of Asymptomatic and Symptomatic SARS-CoV-2 Infection in Children	18
Beta- and Novel Delta-Coronaviruses Are Identified from Wild Animals in the Qinghai-Tibetan Plateau, China	18
COVID-19: Antiviral Agents, Antibody Development and Traditional Chinese Medicine	18
Accelerated Evolution of H7N9 Subtype Influenza Virus under Vaccination Pressure	18
mRNA Vaccines: Possible Tools to Combat SARS-CoV-2	17
Patterns of Gustatory Recovery in Patients Affected by the COVID-19 Outbreak	17
Current Status of Human Papillomavirus-Related Head and Neck Cancer: From Viral Genome to Patient Care	17
Rearrangement of Actin Cytoskeleton by Zika Virus Infection Facilitates Blood–Testis Barrier Hyperpermeability	16
Early Serum HBsAg Kinetics as Predictor of HBsAg Loss in Patients with HBeAg-Negative Chronic Hepatitis B after Treatment with Pegylated Interferonα-2a	16
Immune Responses to Varicella-Zoster Virus Glycoprotein E Formulated with Poly(Lactic-co-Glycolic Acid) Nanoparticles and Nucleic Acid Adjuvants in Mice	16
Human Endogenous Retrovirus Type W Envelope from Multiple Sclerosis Demyelinating Lesions Shows Unique Solubility and Antigenic Characteristics	16
Rapid Acquisition of High-Quality SARS-CoV-2 Genome via Amplicon-Oxford Nanopore Sequencing	16
The Restrictome of Flaviviruses	15
Porcine Immunoglobulin Fc Fused P30/P54 Protein of African Swine Fever Virus Displaying on Surface of S. cerevisiae Elicit Strong Antibody Production in Swine	15
Protective Efficacy of Inactivated Vaccine against SARS-CoV-2 Infection in Mice and Non-Human Primates	15
Comparison of Viromes in Ticks from Different Domestic Animals in China	15
Human PRV Infection in China: An Alarm to Accelerate Eradication of PRV in Domestic Pigs	14
Transcriptome Analyses Implicate Endogenous Retroviruses Involved in the Host Antiviral Immune System through the Interferon Pathway	14
Herpesviruses and the Type III Interferon System	14
The Multifaceted Roles of TAM Receptors during Viral Infection	14
Chimeric Newcastle Disease Virus-like Particles Containing DC-Binding Peptide-Fused Haemagglutinin Protect Chickens from Virulent Newcastle Disease Virus and H9N2 Avian Influenza Virus Challenge	14
Epidemiology and Genotypic Diversity of Eurasian Avian-Like H1N1 Swine Influenza Viruses in China	14
Construction of Non-infectious SARS-CoV-2 Replicons and Their Application in Drug Evaluation	14
Flu Universal Vaccines: New Tricks on an Old Virus	14
Conditionally Reprogrammed Human Normal Airway Epithelial Cells at ALI: A Physiological Model for Emerging Viruses	14
A Crowned Killer’s Résumé: Genome, Structure, Receptors, and Origin of SARS-CoV-2	13
A Virulent PEDV Strain FJzz1 with Genomic Mutations and Deletions at the High Passage Level Was Attenuated in Piglets via Serial Passage In Vitro	13
Identifying the Risk of SARS-CoV-2 Infection and Environmental Monitoring in Airborne Infectious Isolation Rooms (AIIRs)	13
Baculovirus Surface Display of Zika Virus Envelope Protein Protects against Virus Challenge in Mouse Model	13
Monocyte/Macrophage-Mediated Innate Immunity in HIV-1 Infection: From Early Response to Late Dysregulation and Links to Cardiovascular Diseases Onset	13
Correction to: Development of a Novel Reverse Transcription Loop-Mediated Isothermal Amplification Method for Rapid Detection of SARS-CoV-2	13
A Novel Vibriophage vB_VcaS_HC Containing Lysogeny-Related Gene Has Strong Lytic Ability against Pathogenic Bacteria	12
Foot-and-Mouth Disease Virus Inhibits RIP2 Protein Expression to Promote Viral Replication	12
A multi-center study on Molecular Epidemiology of Human Respiratory Syncytial Virus from Children with Acute Lower Respiratory Tract Infections in the Mainland of China between 2015 and 2019	12

Construction and Characterization of a Novel Recombinant Attenuated and Replication-Deficient Candidate Human Adenovirus Type 3 Vaccine: “Adenovirus Vaccine Within an Adenovirus Vector”	12
C19orf66 Inhibits Japanese Encephalitis Virus Replication by Targeting -1 PRF and the NS3 Protein	12
Development of A Super-Sensitive Diagnostic Method for African Swine Fever Using CRISPR Techniques	12
α-Lipoic Acid Exerts Its Antiviral Effect against Viral Hemorrhagic Septicemia Virus (VHSV) by Promoting Upregulation of Antiviral Genes and Suppressing VHSV-Induced Oxidative Stress	12
A Multicenter Study of Viral Aetiology of Community-Acquired Pneumonia in Hospitalized Children in Chinese Mainland	12
Isolation and Growth Characteristics of SARS-CoV-2 in Vero Cell	12
Anti-SARS-CoV-2 IgY Isolated from Egg Yolks of Hens Immunized with Inactivated SARS-CoV-2 for Immunoprophylaxis of COVID-19	12
Effects of N-Linked Glycan on Lassa Virus Envelope Glycoprotein Cleavage, Infectivity, and Immune Response	12
Seroprevalence of Neutralizing Antibodies against Six Human Adenovirus Types Indicates the Low Level of Herd Immunity in Young Children from Guangzhou, China	11
Detection of SARS-CoV-2 RNA in Medical Wastewater in Wuhan During the COVID-19 Outbreak	11
A Self-Biomineralized Novel Adenovirus Vectored COVID-19 Vaccine for Boosting Immunization of Mice	11
The Establishment of Infectious Clone and Single Round Infectious Particles for Coxsackievirus A10	11
Freeze-Drying Formulations Increased the Adenovirus and Poxvirus Vaccine Storage Times and Antigen Stabilities	11
SARS-CoV-2 Does Not Replicate in Aedes Mosquito Cells nor Present in Field-Caught Mosquitoes from Wuhan	11
Antibody Cocktail Exhibits Broad Neutralization Activity Against SARS-CoV-2 and SARS-CoV-2 Variants	10
Prediction of the Receptorome for the Human-Infecting Virome	10
Novel SFTSV Phylogeny Reveals New Reassortment Events and Migration Routes	10
Non-Structural Protein 5 of Zika Virus Interacts with p53 in Human Neural Progenitor Cells and Induces p53-Mediated Apoptosis	10
Generation of A Stable GFP-reporter Zika Virus System for High-throughput Screening of Zika Virus Inhibitors	10
Inefficiency of Sera from Mice Treated with Pseudotyped SARS-CoV to Neutralize 2019-nCoV Infection	10
Host Interferon-Stimulated Gene 20 Inhibits Pseudorabies Virus Proliferation	10
Alterations in Phenotypes and Responses of T Cells Within 6 Months of Recovery from COVID-19: A Cohort Study	10
CRISPR/Cas12a Technology Combined with RT-ERA for Rapid and Portable SARS-CoV-2 Detection	10
Phylogenetic Analysis of the Dengue Virus Strains Causing the 2019 Dengue Fever Outbreak in Hainan, China	10
Consecutive Monitoring of Interleukin-6 Is Needed for COVID-19 Patients	9
Genetic Variation of Multiple Serotypes of Enteroviruses Associated with Hand, Foot and Mouth Disease in Southern China	9
Genetic Analysis of Human Adenovirus Type 7 Strains Circulating in Different Parts of China	9
Desmoglein 2 (DSG2) Is A Receptor of Human Adenovirus Type 55 Causing Adult Severe Community-Acquired Pneumonia	9
Conferring Resistance to Plant RNA Viruses with the CRISPR/CasRx System	9
Depletion but Activation of CD56dimCD16+ NK Cells in Acute Infection with Severe Fever with Thrombocytopenia Syndrome Virus	9
Significant Inhibition of Porcine Epidemic Diarrhea Virus In Vitro by Remdesivir, Its Parent Nucleoside and β-d-N4-hydroxycytidine	9
Japanese Encephalitis Virus NS2B-3 Protein Complex Promotes Cell Apoptosis and Viral Particle Release by Down-Regulating the Expression of AXL	9
Ectopic Expression of TRIM25 Restores RIG-I Expression and IFN Production Reduced by Multiple Enteroviruses 3Cpro	9
PTEN Lipid Phosphatase Activity Enhances Dengue Virus Production through Akt/FoxO1/Maf1 Signaling	9
Recombination of T4-like Phages and Its Activity against Pathogenic Escherichia coli in Planktonic and Biofilm Forms	9
Longitudinal Characteristics of T Cell Responses in Asymptomatic SARS-CoV-2 Infection	9
Hantavirus Infection during Pregnancy	8
mTOR Signaling: The Interface Linking Cellular Metabolism and Hepatitis B Virus Replication	8
Monitoring Neutralization Property Change of Evolving Hantaan and Seoul Viruses with a Novel Pseudovirus-Based Assay	8
Emergence of Zika Virus in Culex tritaeniorhynchus and Anopheles sinensis Mosquitoes in China	8
Human Cytomegalovirus Influences Host circRNA Transcriptions during Productive Infection	8
Human Monoclonal Antibodies: On the Menu of Targeted Therapeutics Against COVID-19	8
Characterizing the Lassa Virus Envelope Glycoprotein Membrane Proximal External Region for Its Role in Fusogenicity	8
GTPase Activity of MxB Contributes to Its Nuclear Location, Interaction with Nucleoporins and Anti-HIV-1 Activity	8
Tumor Necrosis Factor α Reduces SNAP29 Dependent Autolysosome Formation to Increase Prion Protein Level and Promote Tumor Cell Migration	8
Human Endogenous Retroviruses as Biomedicine Markers	8
Sustainability of SARS-CoV-2 Induced Humoral Immune Responses in COVID-19 Patients from Hospitalization to Convalescence Over Six Months	8
PML Suppresses Influenza Virus Replication by Promoting FBXW7 Expression	8
Porcine Picornavirus 3C Protease Degrades PRDX6 to Impair PRDX6-mediated Antiviral Function	7
Identification of Aristolactam Derivatives That Act as Inhibitors of Human Immunodeficiency Virus Type 1 Infection and Replication by Targeting Tat-Mediated Viral Transcription	7
IP10, KC and M-CSF Are Remarkably Increased in the Brains from the Various Strains of Experimental Mice Infected with Different Scrapie Agents	7
SOX5 Regulates Cell Proliferation, Apoptosis, Migration and Invasion in KSHV-Infected Cells	7
Clinical Characteristics of Human Adenovirus Plastic Bronchitis in 10 Pediatric Cases: A Retrospective Study of Seven Years	7
Integrated Metabolomics and Transcriptomics Analyses Reveal Metabolic Landscape in Neuronal Cells during JEV Infection	7
Genomic Characterization of a New Coronavirus from Migratory Birds in Jiangxi Province of China	7
Patients with Prolonged Positivity of SARS-CoV-2 RNA Benefit from Convalescent Plasma Therapy: A Retrospective Study	7
Porcine Bocavirus: A 10-Year History since Its Discovery	7
3H-31, A Non-structural Protein of Heliothis virescens ascovirus 3h, Inhibits the Host Larval Cathepsin and Chitinase Activities	7
Systematic Analysis of 42 Autographa Californica Multiple Nucleopolyhedrovirus Genes Identifies An Additional Six Genes Involved in the Production of Infectious Budded Virus	7
Development of A Neonatal Mouse Model for Coxsackievirus B1 Antiviral Evaluation	7
Differential CircRNA Expression Profiles in PK-15 Cells Infected with Pseudorabies Virus Type II	7
The CREB Regulated Transcription Coactivator 2 Suppresses HIV-1 Transcription by Preventing RNA Pol II from Binding to HIV-1 LTR	7
Establishment of a Reverse Genetic System of Severe Fever with Thrombocytopenia Syndrome Virus Based on a C4 Strain	7