Journal of Genetics and Genomics

Article	Citations
EVenn: Easy to create repeatable and editable Venn diagrams and Venn networks online	223
Evidence for a mouse origin of the SARS-CoV-2 Omicron variant	214
TaxonKit: A practical and efficient NCBI taxonomy toolkit	171
Nitrogen assimilation in plants: current status and future prospects	130
Single-cell transcriptome atlas of the leaf and root of rice seedlings	108
Mitochondrial sirtuins, metabolism, and aging	103
COVID-19 mRNA vaccines	65
Plants response to light stress	49
Gut microbiota, inflammation, and molecular signatures of host response to infection	48
Insights into plant salt stress signaling and tolerance	48
Why is oocyte aneuploidy increased with maternal aging?	44
Spatially resolved transcriptomics: a comprehensive review of their technological advances, applications, and challenges	44
Plant pan-genomics: recent advances, new challenges, and roads ahead	42
Natural variations in grain length 10 (GL10) regulate rice grain size	38
From plant immunity to crop disease resistance	38
OsbZIP60-mediated unfolded protein response regulates grain chalkiness in rice	37
The molecular mechanism of plasma membrane H+-ATPases in plant responses to abiotic stress	34
Tumor necrosis factor-α signaling in nonalcoholic steatohepatitis and targeted therapies	34
The CRISPR/Cas9 revolution continues: From base editing to prime editing in plant science	32
Progressive deterioration of the upper respiratory tract and the gut microbiomes in children during the early infection stages of COVID-19	31
Genome editing in plants with MAD7 nuclease	31
Disruption of the autism-related gene Pak1 causes stereocilia disorganization, hair cell loss, and deafness in mice	31
Understanding the mechanistic regulation of ferroptosis in cancer: the gene matters	29
Hd1, Ghd7, and DTH8 synergistically determine the rice heading date and yield-related agronomic traits	28
EphA2: A promising therapeutic target in breast cancer	28

Altered gut microbiome in FUT2 loss-of-function mutants in support of personalized medicine for inflammatory bowel diseases	27
Regulation and integration of plant jasmonate signaling: a comparative view of monocot and dicot	27
Nitric oxide negatively regulates gibberellin signaling to coordinate growth and salt tolerance in Arabidopsis	27
Microbiota-gut-brain axis in autism spectrum disorder	27
Large-scale pharmacogenomic studies and drug response prediction for personalized cancer medicine	26
Characteristic dysbiosis in gout and the impact of a uric acid-lowering treatment, febuxostat on the gut microbiota	26
Arabidopsis RPD3-like histone deacetylases form multiple complexes involved in stress response	26
The HuaBiao project: whole-exome sequencing of 5000 Han Chinese individuals	26
Single-cell brain atlas of Parkinson's disease mouse model	25
Understanding the genetic and molecular constitutions of heterosis for developing hybrid rice	25
Variants in the Wnt co-receptor LRP6 are associated with familial exudative vitreoretinopathy	24
Abiotic stress-triggered oxidative challenges: Where does H2S act?	23
PI3K/Akt/mTOR signaling orchestrates the phenotypic transition and chemo-resistance of small cell lung cancer	22
OsMPK4 promotes phosphorylation and degradation of IPA1 in response to salt stress to confer salt tolerance in rice	22
Exome sequencing reveals genetic architecture in patients with isolated or syndromic short stature	22
CircRNA: a rising star in plant biology	22
Genomic insight into the divergence and adaptive potential of a forgotten landrace G. hirsutum L. purpurascens	21
Modulating the C-terminus of DEP1 synergistically enhances grain quality and yield in rice	20
Newborn screening with targeted sequencing: a multicenter investigation and a pilot clinical study in China	20
Comparative study of gut microbiota from captive and confiscated-rescued wild pangolins	20
Polycomb-group proteins in the initiation and progression of cancer	20
The challenge of emerging SARS-CoV-2 mutants to vaccine development	19
The oral microbiome of pregnant women facilitates gestational diabetes discrimination	19
Functional characterization of powdery mildew resistance gene MlIW172, a new Pm60 allele and its allelic variation in wild emmer wheat	19
Sporophytic control of anther development and male fertility by glucose-6-phosphate/phosphate translocator 1 (OsGPT1) in rice	19
Circular RNA ubiquitin-associated protein 2 enhances autophagy and promotes colorectal cancer progression and metastasis via miR-582-5p/FOXO1 signaling	19
GenomeSyn: a bioinformatics tool for visualizing genome synteny and structural variations	19
Fructose and fructose kinase in cancer and other pathologies	19
A high-resolution cell atlas of the domestic pig lung and an online platform for exploring lung single-cell data	19
Nucleolar histone deacetylases HDT1, HDT2, and HDT3 regulate plant reproductive development	18
Brassinosteroid signaling and molecular crosstalk with nutrients in plants	18
Mitotic inheritance of DNA methylation: more than just copy and paste	18
Phase separation in RNA biology	17
A hypothetical model of trans-acting R-loops-mediated promoter-enhancer interactions by Alu elements	17
Genetic manipulations of TaARE1 boost nitrogen utilization and grain yield in wheat	17
CRISPR-mediated host genomic DNA damage is efficiently repaired through microhomology-mediated end joining in Zymomonas mobilis	17
The Melastoma dodecandrum genome and the evolution of Myrtales	17
Phosphorylation of an ethylene response factor by MPK3/MPK6 mediates negative feedback regulation of pathogen-induced ethylene biosynthesis in Arabidopsis	17
Inducible CRISPRa screen identifies putative enhancers	17
Current status and perspectives of regulatory T cell-based therapy	17
Molecular insights into the transgenerational inheritance of stress memory	17
Genomic analyses reveal distinct genetic architectures and selective pressures in Chinese donkeys	16
GGVD: A goat genome variation database for tracking the dynamic evolutionary process of selective signatures and ancient introgressions	16
Function of hydroxycinnamoyl transferases for the biosynthesis of phenolamides in rice resistance to Magnaporthe oryzae	16
Molecular epigenetic mechanisms for the memory of temperature stresses in plants	16
Identifying a melanogenesis-related candidate gene by a high-quality genome assembly and population diversity analysis in Hypsizygus marmoreus	16
Suppressed mitochondrial respiration via NOX5-mediated redox imbalance contributes to the antitumor activity of anlotinib in oral squamous cell carcinoma	15
RNA-binding motif protein RBM47 promotes tumorigenesis in nasopharyngeal carcinoma through multiple pathways	15
KDM2B promotes cell viability by enhancing DNA damage response in canine hemangiosarcoma	15
Fecal microbiota transplantation from young donor mice improves ovarian function in aged mice	14

The gut microbiome and microbial metabolites in acute myocardial infarction	14
Quantitative proteomics reveals key pathways in the symbiotic interface and the likely extracellular property of soybean symbiosome	14
Phylogeny and sex chromosome evolution of Palaeognathae	14
Maternal genetic structure of a neolithic population of the Yangshao culture	14
Highly Regional Genes: graph-based gene selection for single-cell RNA-seq data	14
Chromosome organization and gene expansion in the highly fragmented genome of the ciliate Strombidium stylifer	14
Carrageenan oligosaccharides and associated carrageenan-degrading bacteria induce intestinal inflammation in germ-free mice	13
Single-cell RNA-seq analysis of testicular somatic cell development in pigs	13
Polyamine oxidase 3 is involved in salt tolerance at the germination stage in rice	13
Addition of the T5 exonuclease increases the prime editing efficiency in plants	13
The quantitative proteome atlas of a model cyanobacterium	13
Sox9+ cells are required for salivary gland regeneration after radiation damage via the Wnt/β-catenin pathway	13
Deciphering spike architecture formation towards yield improvement in wheat	13
Regulation of nitrogen starvation responses by the alarmone (p)ppGpp in rice	13
Cervicovaginal microbiome dynamics after taking oral probiotics	13
VSOLassoBag: a variable-selection oriented LASSO bagging algorithm for biomarker discovery in omic-based translational research	12
Genomic surveillance of Nevada patients revealed prevalence of unique SARS-CoV-2 variants bearing mutations in the RdRp gene	12
TaBZR1 enhances wheat salt tolerance via promoting ABA biosynthesis and ROS scavenging	12
Chemical screening reveals Ronidazole is a superior prodrug to Metronidazole for nitroreductase-induced cell ablation system in zebrafish larvae	12
GAEP: a comprehensive genome assembly evaluating pipeline	12
OsLTP47 may function in a lipid transfer relay essential for pollen wall development in rice	12
Ether phospholipids govern ferroptosis	12
Ufl1 deficiency causes kidney atrophy associated with disruption of endoplasmic reticulum homeostasis	12
Two plant NLR proteins confer strain-specific resistance conditioned by an effector from Pseudomonas syringae pv. actinidiae	12
eQTL studies: from bulk tissues to single cells	12
Comprehensive understanding to the public health risk of environmental microbes via a microbiome-based index	12
Genome sequence and transcriptome of Sorbus pohuashanensis provide insights into population evolution and leaf sunburn response	12
The chromatin remodeling complex imitation of switch controls stamen filament elongation by promoting jasmonic acid biosynthesis in Arabidopsis	11
Von Hippel-Lindau tumor suppressor pathways & corresponding therapeutics in kidney cancer	11
Two zinc-finger proteins control the initiation and elongation of long stalk trichomes in tomato	11
Planar cell polarity regulators in asymmetric organogenesis during development and disease	11
The mechanisms of nucleotide actions in insulin resistance	11
Emerging functions of tRNA modifications in mRNA translation and diseases	11
MIT1, encoding a 15-cis-ζ-carotene isomerase, regulates tiller number and stature in rice	11
Leptin gene-targeted editing in ob/ob mouse adipose tissue based on the CRISPR/Cas9 system	10
A REF6-dependent H3K27me3-depleted state facilitates gene activation during germination in Arabidopsis	10
The advancements, challenges, and future implications of the CRISPR/Cas9 system in swine research	10
Nitric oxide-mediated S-nitrosylation of IAA17 protein in intrinsically disordered region represses auxin signaling	10
GenOrigin: A comprehensive protein-coding gene origination database on the evolutionary timescale of life	10
The rice histone methylation regulates hub species of the root microbiota	10
Targeted sequencing and integrative analysis of 3,195 Chinese patients with neurodevelopmental disorders prioritized 26 novel candidate genes	10
Active DNA demethylation regulates MAMP-triggered immune priming in Arabidopsis	10
Derlin-1 and TER94/VCP/p97 are required for intestinal homeostasis	10
Long-term correction of hemophilia B through CRISPR/Cas9 induced homology-independent targeted integration	10
The camphor tree genome enhances the understanding of magnoliid evolution	10
Human HAND1 inhibits the conversion of cholesterol to steroids in trophoblasts	9
Genomes of 12 fig wasps provide insights into the adaptation of pollinators to fig syconia	9
A heavy metal transporter gene ZmHMA3a promises safe agricultural production on cadmium-polluted arable land	9
Ancient DNA reveals the maternal genetic history of East Asian domestic pigs	9
Translation machinery: the basis of translational control	9
The composition, function, and regulation of adipose stem and progenitor cells	9
Reproductive aging: biological pathways and potential interventive strategies	9
A p53/CPEB2 negative feedback loop regulates renal cancer cell proliferation and migration	9
Mechanisms underlying key agronomic traits and implications for molecular breeding in soybean	9
Deciphering the evolution and complexity of wheat germplasm from a genomic perspective	9
OsMLH1 interacts with OsMLH3 to regulate synapsis and interference-sensitive crossover formation during meiosis in rice	9
A genome-wide association study of facial morphology identifies novel genetic loci in Han Chinese	9
Caenorhabditis elegans homologue of Fam210 is required for oogenesis and reproduction	9
Genetics of anorexia nervosa: An overview of genome-wide association studies and emerging biological links	8
Epigenome-Metabolome-Epigenome signaling cascade in cell biological processes	8
Conditional gene expression in invertebrate animal models	8
Sequence motifs and prediction model of GBE editing outcomes based on target library analysis and machine learning	8
CRISPR-mediated acceleration of wheat improvement: advances and perspectives	8
scEpiTools: a database to comprehensively interrogate analytic tools for single-cell epigenomic data	8
Aberrant nuclear lamina contributes to the malignancy of human gliomas	8
The S100 calcium binding protein A11 promotes liver fibrogenesis by targeting TGF-β signaling	8
Peripheral and central control of obesity by primary cilia	8
Protein post-translational modifications in auxin signaling	8
Loss-of-function of KMT5B leads to neurodevelopmental disorder and impairs neuronal development and neurogenesis	8
Pathway analysis for genome-wide genetic variation data: Analytic principles, latest developments, and new opportunities	8
HPDL deficiency causes a neuromuscular disease by impairing the mitochondrial respiration	8
Delineating the longitudinal tumor evolution using organoid models	8
Tn5-FISH, a novel cytogenetic method to image chromatin interactions with sub-kilobase resolution	8
Single-cell transcriptomic profiling of the hypothalamic median eminence during aging	8
Building a cattle pan-genome using more de novo assemblies	8
Maternal genetic history of southern East Asians over the past 12,000 years	8
Nuclear encoded elongation factor EF-Tu is required for chloroplast development in rice grown under low-temperature conditions	8
Improved in situ sequencing for high-resolution targeted spatial transcriptomic analysis in tissue sections	8
The evolution of sex chromosome dosage compensation in animals	8
The sex determination gene doublesex is required during adulthood to maintain sexual orientation	8

Alteration of the respiratory microbiome in COVID-19 patients with different severities	8
Novel compound heterozygous variants in dynein axonemal heavy chain 17 cause asthenoteratospermia with sperm flagellar defects	8
Interplay between genome organization and epigenomic alterations of pericentromeric DNA in cancer	8
Smyd1 is essential for myosin expression and sarcomere organization in craniofacial, extraocular, and cardiac muscles	8
Maternal genetic history of ancient Tibetans over the past 4000 years	8
Multiomics metabolic and epigenetics regulatory network in cancer: A systems biology perspective	8
Loss of Wtap results in cerebellar ataxia and degeneration of Purkinje cells	7
LHCGR and ALMS1 defects likely cooperate in the development of polycystic ovary syndrome indicated by double-mutant mice	7
Correlation of DNA methylation patterns to the phenotypic features of Tibetan elite alpinists in extreme hypoxia	7
O-GlcNAcylation regulates phagocytosis by promoting Ezrin localization at the cell cortex	7
3D genome organization in the central nervous system, implications for neuropsychological disorders	7
Cryo-EM structure of R-loop monoclonal antibody S9.6 in recognizing RNA:DNA hybrids	7
Geranylgeranyl pyrophosphate-mediated protein geranylgeranylation regulates endothelial cell proliferation and apoptosis during vasculogenesis in mouse embryo	7
TEAseq-based identification of 35,696 Dissociation insertional mutations facilitates functional genomic studies in maize	7
Molecular basis for the selective recognition and ubiquitination of centromeric histone H3 by yeast E3 ligase Psh1	7
Kilobase-scale genomic deletion of DOTFL1 in Dendrobium orchids	7
Integrating multi-modal information to detect spatial domains of spatial transcriptomics by graph attention network	7
Genome-wide selection and introgression of Chinese rice varieties during breeding	7
Correction of a CADASIL point mutation using adenine base editors in hiPSCs and blood vessel organoids	7
Allele-specific expression and splicing provide insight into the phenotypic differences between thin- and fat-tailed sheep breeds	7
Cyclin A2/cyclin-dependent kinase 1-dependent phosphorylation of Top2a is required for S phase entry during retinal development in zebrafish	7
G-quadruplexes in genomes of viruses infecting eukaryotes or prokaryotes are under different selection pressures from hosts	7
PIFs interact with SWI2/SNF2-related 1 complex subunit 6 to regulate H2A.Z deposition and photomorphogenesis in Arabidopsis	6
OsASHL1 and OsASHL2, two members of the COMPASS-like complex, control floral transition and plant development in rice	6
New insights into the dispersion history and adaptive evolution of taxon Aegilops tauschii in China	6
Transcriptional control of pancreatic β-cell identity and plasticity during the pathogenesis of type 2 diabetes	6
TabHLH95-TaNF-YB1 module promotes grain starch synthesis in bread wheat	6
Genetic and lipidomic analyses reveal the key role of lipid metabolism for cold tolerance in maize	6
The shikimate pathway regulates programmed cell death	6
Systematic annotation of conservation states provides insights into regulatory regions in rice	6
Genetic structure and domestication footprints of the tusk, coat color, and ear morphology in East Chinese pigs	6
Cochlear hair cells of echolocating bats are immune to intense noise	6
Infection of SARS-CoV-2 causes severe pathological changes in mouse testis	6
Adrb1 and Adrb2b are the major β-adrenergic receptors regulating body axis straightening in zebrafish	6
FISH-based “pan” and “core” karyotypes reveal genetic diversification of Roegneria ciliaris	6
GRB10 regulates β-cell mass by inhibiting β-cell proliferation and stimulating β-cell dedifferentiation	6
Natural variation in the SVP contributes to the pleiotropic adaption of Arabidopsis thaliana across contrasted habitats	6
Deletion of CHD8 in cerebellar granule neuron progenitors leads to severe cerebellar hypoplasia, ataxia, and psychiatric behavior in mice	6
Laser capture microdissection for biomedical research: towards high-throughput, multi-omics, and single-cell resolution	6
Developmental regulation of neuronal gene expression by Elongator complex protein 1 dosage	6
Ancient Y-DNA with reconstructed phylogeny provides insights into the demographic history of paternal haplogroup N1a2-F1360	6
The role of genotype and diet in shaping gut microbiome in a genetic vitamin A deficient mouse model	6
Genomic and transcriptomic analyses enable the identification of important genes associated with subcutaneous fat deposition in Holstein cows	6
A novel PCYT2 mutation identified in a Chinese consanguineous family with hereditary spastic paraplegia	6
Whole-genome sequences shed light on the demographic history and contemporary genetic erosion of free-ranging jaguar (Panthera onca) populations	6
The transcription factor Sox30 is involved in Nile tilapia spermatogenesis	6
Distinguished biological adaptation architecture aggravated population differentiation of Tibeto-Burman-speaking people	6
Alanine aminotransferase (OsAlaAT1) modulates nitrogen utilization, grain yield, and quality in rice	6
Emerging roles of phosphoinositide-associated membrane trafficking in plant stress responses	6
Phosphorylation of Ago2 is required for its role in DNA double-strand break repair	6
A Bama miniature pig model of monoallelic TSC1 mutation for human tuberous sclerosis complex	6
Gene therapy for monogenic disorders: challenges, strategies, and perspectives	6
A recurrent mutation in TBPL2 causes diminished ovarian reserve and female infertility	6
Cdx1b protects intestinal cell fate by repressing signaling networks for liver specification	6
VT3D: a visualization toolbox for 3D transcriptomic data	6
Nucleolus-localized Def-CAPN3 protein degradation pathway and its role in cell cycle control and ribosome biogenesis	6
SeqCor: correct the effect of guide RNA sequences in clustered regularly interspaced short palindromic repeats/Cas9 screening by machine learning algorithm	6
Molecular cytogenetic map visualizes the heterozygotic genome and identifies translocation chromosomes in Citrus sinensis	6
An instantaneous coalescent method insensitive to population structure	5
Reconstructing cell lineage trees with genomic barcoding: approaches and applications	5
Regulation of chloroplast protein degradation	5
Juvenile hormone receptor Met regulates sleep and neuronal morphology via glial-neuronal crosstalk	5
Deciphering the regulatory code of histone modifications in plants	5
Reproductive tissue-specific translatome of a rice thermo-sensitive genic male sterile line	5
Two diversities meet in the rhizosphere: root specialized metabolites and microbiome	5
Functional analysis of the emerging roles for the KISS1/KISS1R signaling pathway in cancer metastasis	5
Humoral and cellular immunity against diverse SARS-CoV-2 variants	5
Emerging roles and therapeutic potentials of sphingolipids in pathophysiology: emphasis on fatty acyl heterogeneity	5
Noninvasive preimplantation genetic testing in assisted reproductive technology: current state and future perspectives	5
Heterotrimeric G protein γ subunit DEP1 synergistically regulates grain quality and yield by modulating the TTP (TON1-TRM-PP2A) complex in rice	5
Creating future crops: a revolution for sustainable agriculture	5
Lung stem cells in regeneration and tumorigenesis	5
The ZFP541-KCTD19 complex is essential for pachytene progression by activating meiotic genes during mouse spermatogenesis	5
CRISPR-detector: fast and accurate detection, visualization, and annotation of genome-wide mutations induced by genome editing events	5
GTPase-activating protein TBC1D5 coordinates with retromer to constrain synaptic growth by inhibiting BMP signaling	5
Homozygous nonsense variants of KCTD19 cause male infertility in humans and mice	5
Characterization of heavy-chain antibody gene repertoires in Bactrian camels	5
Microbiota-mediated shaping of mouse spleen structure and immune function characterized by scRNA-seq and Stereo-seq	5
Current therapies for osteoarthritis and prospects of CRISPR-based genome, epigenome, and RNA editing in osteoarthritis treatment	5
Arabidopsis CAP1 mediates ammonium-regulated root hair growth by influencing vesicle trafficking and the cytoskeletal arrangement in root hair cells	5
Micro-coevolution of host genetics with gut microbiome in three Chinese ethnic groups	5
Improving the Cpf1-mediated base editing system by combining dCas9/dead sgRNA with human APOBEC3A variants	5
Key regulators of intestinal stem cells: diet, microbiota, and microbial metabolites	5
The archaeogenomic validation of Saint Ladislaus' relic provides insights into the Árpád dynasty's genealogy	4
PARK16 locus: Differential effects of the non-coding rs823114 on Parkinson’s disease risk, RNA expression, and DNA methylation	4
Single-cell transcriptomics reveals cell type diversity of human prostate	4
LIMK2 is required for membrane cytoskeleton reorganization of contracting airway smooth muscle	4
Targeted lipidomics reveals plasmalogen phosphatidylethanolamines and storage triacylglycerols as the major systemic lipid aberrations in Bietti crystalline corneoretinal dystrophy	4
Phosphatidylcholine deficiency increases ferroptosis susceptibility in the Caenorhabditis elegans germline	4
Hsa_Circ_0000826 inhibits the proliferation of colorectal cancer by targeting AUF1	4
Mesenteric lymph system constitutes the second route in gut–liver axis and transports metabolism-modulating gut microbial metabolites	4
A single-cell atlas of mouse olfactory bulb chromatin accessibility	4
AtPQT11, a P450 enzyme, detoxifies paraquat via N-demethylation	4
ROS is essential for initiation of energy deprivation-induced autophagy	4
Independent variations in genome-wide expression, alternative splicing, and DNA methylation in brain tissues among castes of the buff-tailed bumblebee, Bombus terrestris	4