Journal of Genetics and Genomics

Article	Citations
Evidence for a mouse origin of the SARS-CoV-2 Omicron variant	193
EVenn: Easy to create repeatable and editable Venn diagrams and Venn networks online	167
TaxonKit: A practical and efficient NCBI taxonomy toolkit	135
Single-cell transcriptome atlas of the leaf and root of rice seedlings	80
Nitrogen assimilation in plants: current status and future prospects	74
Single-cell RNA sequencing identifies novel cell types in Drosophila blood	72
Mitochondrial sirtuins, metabolism, and aging	72
COVID-19 mRNA vaccines	59
CRISPR/Cas9-mediated disruption of TaNP1 genes results in complete male sterility in bread wheat	53
Gut microbiota, inflammation, and molecular signatures of host response to infection	47
HPV-CCDC106 integration alters local chromosome architecture and hijacks an enhancer by three-dimensional genome structure remodeling in cervical cancer	44
CRISPR/Cas9 editing of wheat TaQ genes alters spike morphogenesis and grain threshability	40
CTP synthase forms cytoophidia in archaea	39
Plants response to light stress	35
Longitudinal epitranscriptome profiling reveals the crucial role of N6-methyladenosine methylation in porcine prenatal skeletal muscle development	34
Why is oocyte aneuploidy increased with maternal aging?	33
DNA methyltransferases in hematological malignancies	32
The CRISPR/Cas9 revolution continues: From base editing to prime editing in plant science	30
The atlas of cytoophidia in Drosophila larvae	29
Disruption of the autism-related gene Pak1 causes stereocilia disorganization, hair cell loss, and deafness in mice	29
Investigation of CRISPR/Cas9-induced SD1 rice mutants highlights the importance of molecular characterization in plant molecular breeding	29
The molecular mechanism of plasma membrane H+-ATPases in plant responses to abiotic stress	28
OsbZIP60-mediated unfolded protein response regulates grain chalkiness in rice	28
Natural variations in grain length 10 (GL10) regulate rice grain size	27
Dynamics of severe acute respiratory syndrome coronavirus 2 genome variants in the feces during convalescence	26

Progressive deterioration of the upper respiratory tract and the gut microbiomes in children during the early infection stages of COVID-19	26
Nitric oxide negatively regulates gibberellin signaling to coordinate growth and salt tolerance in Arabidopsis	26
Genome editing in plants with MAD7 nuclease	25
Plant pan-genomics: recent advances, new challenges, and roads ahead	25
Tumor necrosis factor-α signaling in nonalcoholic steatohepatitis and targeted therapies	24
From plant immunity to crop disease resistance	24
The proline synthesis enzyme P5CS forms cytoophidia in Drosophila	23
Characteristic dysbiosis in gout and the impact of a uric acid-lowering treatment, febuxostat on the gut microbiota	22
EphA2: A promising therapeutic target in breast cancer	22
Understanding the genetic and molecular constitutions of heterosis for developing hybrid rice	21
Microbiota-gut-brain axis in autism spectrum disorder	21
Two homologous INDOLE-3-ACETAMIDE (IAM) HYDROLASE genes are required for the auxin effects of IAM in Arabidopsis	21
The HuaBiao project: whole-exome sequencing of 5000 Han Chinese individuals	21
Single-cell brain atlas of Parkinson's disease mouse model	20
The dichotomous role of TGF-β in controlling liver cancer cell survival and proliferation	20
Regulation and integration of plant jasmonate signaling: a comparative view of monocot and dicot	20
Exome sequencing reveals genetic architecture in patients with isolated or syndromic short stature	20
Large-scale pharmacogenomic studies and drug response prediction for personalized cancer medicine	19
Altered gut microbiome in FUT2 loss-of-function mutants in support of personalized medicine for inflammatory bowel diseases	19
Hd1, Ghd7, and DTH8 synergistically determine the rice heading date and yield-related agronomic traits	19
PI3K/Akt/mTOR signaling orchestrates the phenotypic transition and chemo-resistance of small cell lung cancer	19
Genomic insight into the divergence and adaptive potential of a forgotten landrace G. hirsutum L. purpurascens	19
Abiotic stress-triggered oxidative challenges: Where does H2S act?	19
The challenge of emerging SARS-CoV-2 mutants to vaccine development	19
Comparative study of gut microbiota from captive and confiscated-rescued wild pangolins	19
Arabidopsis RPD3-like histone deacetylases form multiple complexes involved in stress response	18
A high-resolution cell atlas of the domestic pig lung and an online platform for exploring lung single-cell data	18
Many facades of CTCF unified by its coding for three-dimensional genome architecture	18
CircRNA: a rising star in plant biology	18
Fructose and fructose kinase in cancer and other pathologies	17
Newborn screening with targeted sequencing: a multicenter investigation and a pilot clinical study in China	16
The oral microbiome of pregnant women facilitates gestational diabetes discrimination	16
Polycomb-group proteins in the initiation and progression of cancer	16
Genetic manipulations of TaARE1 boost nitrogen utilization and grain yield in wheat	16
OsMPK4 promotes phosphorylation and degradation of IPA1 in response to salt stress to confer salt tolerance in rice	16
Insights into plant salt stress signaling and tolerance	15
Generation of rat blood vasculature and hematopoietic cells in rat-mouse chimeras by blastocyst complementation	15
The Melastoma dodecandrum genome and the evolution of Myrtales	14
Genomic analyses reveal distinct genetic architectures and selective pressures in Chinese donkeys	14
Variants in the Wnt co-receptor LRP6 are associated with familial exudative vitreoretinopathy	14
CRISPR-mediated host genomic DNA damage is efficiently repaired through microhomology-mediated end joining in Zymomonas mobilis	14
Understanding the mechanistic regulation of ferroptosis in cancer: the gene matters	14
Genomic atlases of introgression and differentiation reveal breeding footprints in Chinese cultivated rice	14
Phase separation in RNA biology	14
Mutation of DELAYED GREENING1 impairs chloroplast RNA editing at elevated ambient temperature in Arabidopsis	14
Spatially resolved transcriptomics: a comprehensive review of their technological advances, applications, and challenges	14
Analyses of functional conservation and divergence reveal requirement of bHLH010/089/091 for pollen development at elevated temperature in Arabidopsis	13
Lessons from expanded potential of embryonic stem cells: Moving toward totipotency	13
Nucleolar histone deacetylases HDT1, HDT2, and HDT3 regulate plant reproductive development	13
Sporophytic control of anther development and male fertility by glucose-6-phosphate/phosphate translocator 1 (OsGPT1) in rice	13

Circular RNA ubiquitin-associated protein 2 enhances autophagy and promotes colorectal cancer progression and metastasis via miR-582-5p/FOXO1 signaling	13
Quantitative proteomics reveals key pathways in the symbiotic interface and the likely extracellular property of soybean symbiosome	13
Genomic surveillance of Nevada patients revealed prevalence of unique SARS-CoV-2 variants bearing mutations in the RdRp gene	13
Molecular insights into the transgenerational inheritance of stress memory	13
GGVD: A goat genome variation database for tracking the dynamic evolutionary process of selective signatures and ancient introgressions	12
KDM2B promotes cell viability by enhancing DNA damage response in canine hemangiosarcoma	12
Modulating the C-terminus of DEP1 synergistically enhances grain quality and yield in rice	12
Suppressed mitochondrial respiration via NOX5-mediated redox imbalance contributes to the antitumor activity of anlotinib in oral squamous cell carcinoma	12
Identifying a melanogenesis-related candidate gene by a high-quality genome assembly and population diversity analysis in Hypsizygus marmoreus	12
Inducible CRISPRa screen identifies putative enhancers	12
Regulation of nitrogen starvation responses by the alarmone (p)ppGpp in rice	12
Molecular epigenetic mechanisms for the memory of temperature stresses in plants	12
Functional characterization of powdery mildew resistance gene MlIW172, a new Pm60 allele and its allelic variation in wild emmer wheat	12
Chromosome organization and gene expansion in the highly fragmented genome of the ciliate Strombidium stylifer	12
GenomeSyn: a bioinformatics tool for visualizing genome synteny and structural variations	12
A hypothetical model of trans-acting R-loops-mediated promoter-enhancer interactions by Alu elements	12
Ufl1 deficiency causes kidney atrophy associated with disruption of endoplasmic reticulum homeostasis	11
Ether phospholipids govern ferroptosis	11
Mitotic inheritance of DNA methylation: more than just copy and paste	11
Phylogeny and sex chromosome evolution of Palaeognathae	11
Polyamine oxidase 3 is involved in salt tolerance at the germination stage in rice	11
Carrageenan oligosaccharides and associated carrageenan-degrading bacteria induce intestinal inflammation in germ-free mice	11
Targeted sequencing and integrative analysis of 3,195 Chinese patients with neurodevelopmental disorders prioritized 26 novel candidate genes	11
Chemical screening reveals Ronidazole is a superior prodrug to Metronidazole for nitroreductase-induced cell ablation system in zebrafish larvae	11
The novel male meiosis recombination regulator coordinates the progression of meiosis prophase I	11
Phosphorylation of an ethylene response factor by MPK3/MPK6 mediates negative feedback regulation of pathogen-induced ethylene biosynthesis in Arabidopsis	11
RNA-binding motif protein RBM47 promotes tumorigenesis in nasopharyngeal carcinoma through multiple pathways	11
The chromatin remodeling complex imitation of switch controls stamen filament elongation by promoting jasmonic acid biosynthesis in Arabidopsis	10
A functional missense variant in ITIH3 affects protein expression and neurodevelopment and confers schizophrenia risk in the Han Chinese population	10
Function of hydroxycinnamoyl transferases for the biosynthesis of phenolamides in rice resistance to Magnaporthe oryzae	10
MIT1, encoding a 15-cis-ζ-carotene isomerase, regulates tiller number and stature in rice	10
Highly Regional Genes: graph-based gene selection for single-cell RNA-seq data	10
Current status and perspectives of regulatory T cell-based therapy	10
Landscape of transcript isoforms in single T cells infiltrating in non-small-cell lung cancer	10
A critical role of foxp3a-positive regulatory T cells in maintaining immune homeostasis in zebrafish testis development	10
Deciphering spike architecture formation towards yield improvement in wheat	10
Active DNA demethylation regulates MAMP-triggered immune priming in Arabidopsis	10
Comprehensive understanding to the public health risk of environmental microbes via a microbiome-based index	9
Leptin gene-targeted editing in ob/ob mouse adipose tissue based on the CRISPR/Cas9 system	9
Two plant NLR proteins confer strain-specific resistance conditioned by an effector from Pseudomonas syringae pv. actinidiae	9
Genome transfer for the prevention of female infertility caused by maternal gene mutation	9
A genome-wide association study of facial morphology identifies novel genetic loci in Han Chinese	9
Fecal microbiota transplantation from young donor mice improves ovarian function in aged mice	9
GenOrigin: A comprehensive protein-coding gene origination database on the evolutionary timescale of life	9
Derlin-1 and TER94/VCP/p97 are required for intestinal homeostasis	9
OsLTP47 may function in a lipid transfer relay essential for pollen wall development in rice	9
Asthma-associated polymorphisms in 17q12-21 locus modulate methylation and gene expression of GSDMA in naïve CD4+ T cells	9
The quantitative proteome atlas of a model cyanobacterium	9
Genome sequence and transcriptome of Sorbus pohuashanensis provide insights into population evolution and leaf sunburn response	9
The rice histone methylation regulates hub species of the root microbiota	9
Caenorhabditis elegans homologue of Fam210 is required for oogenesis and reproduction	8
Cervicovaginal microbiome dynamics after taking oral probiotics	8
Tn5-FISH, a novel cytogenetic method to image chromatin interactions with sub-kilobase resolution	8
The gut microbiome and microbial metabolites in acute myocardial infarction	8
Single-cell RNA-seq analysis of testicular somatic cell development in pigs	8
Decoding the plant genome: From epigenome to 3D organization	8
The advancements, challenges, and future implications of the CRISPR/Cas9 system in swine research	8
Smyd1 is essential for myosin expression and sarcomere organization in craniofacial, extraocular, and cardiac muscles	8
Von Hippel-Lindau tumor suppressor pathways & corresponding therapeutics in kidney cancer	8
Two zinc-finger proteins control the initiation and elongation of long stalk trichomes in tomato	8
VSOLassoBag: a variable-selection oriented LASSO bagging algorithm for biomarker discovery in omic-based translational research	8
Phosphatidylinositol 4-kinase β is required for the ciliogenesis of zebrafish otic vesicle	8
Loss of Rbm24a causes defective hair cell development in the zebrafish inner ear and neuromasts	8
Single-cell transcriptomic profiling of the hypothalamic median eminence during aging	7
The S100 calcium binding protein A11 promotes liver fibrogenesis by targeting TGF-β signaling	7
Maternal genetic structure of a neolithic population of the Yangshao culture	7
The mechanisms of nucleotide actions in insulin resistance	7
Conditional gene expression in invertebrate animal models	7
Allele-specific expression and splicing provide insight into the phenotypic differences between thin- and fat-tailed sheep breeds	7
Delineating the longitudinal tumor evolution using organoid models	7
Building a cattle pan-genome using more de novo assemblies	7
Planar cell polarity regulators in asymmetric organogenesis during development and disease	7
The camphor tree genome enhances the understanding of magnoliid evolution	7
Clinical utility of whole genome sequencing for the detection of mitochondrial genome mutations	7
The sex determination gene doublesex is required during adulthood to maintain sexual orientation	7
Alteration of the respiratory microbiome in COVID-19 patients with different severities	7
Molecular basis for the selective recognition and ubiquitination of centromeric histone H3 by yeast E3 ligase Psh1	7
A heavy metal transporter gene ZmHMA3a promises safe agricultural production on cadmium-polluted arable land	7
Addition of the T5 exonuclease increases the prime editing efficiency in plants	7
Intestinal stem cells and intestinal organoids	7

A p53/CPEB2 negative feedback loop regulates renal cancer cell proliferation and migration	7
Brassinosteroid signaling and molecular crosstalk with nutrients in plants	7
Human HAND1 inhibits the conversion of cholesterol to steroids in trophoblasts	7
TEAseq-based identification of 35,696 Dissociation insertional mutations facilitates functional genomic studies in maize	7
O-GlcNAcylation regulates phagocytosis by promoting Ezrin localization at the cell cortex	6
Correlation of DNA methylation patterns to the phenotypic features of Tibetan elite alpinists in extreme hypoxia	6
DVL mutations identified from human neural tube defects and Dandy-Walker malformation obstruct the Wnt signaling pathway	6
SeqCor: correct the effect of guide RNA sequences in clustered regularly interspaced short palindromic repeats/Cas9 screening by machine learning algorithm	6
Loss-of-function of KMT5B leads to neurodevelopmental disorder and impairs neuronal development and neurogenesis	6
Interplay between genome organization and epigenomic alterations of pericentromeric DNA in cancer	6
Transcriptional control of pancreatic β-cell identity and plasticity during the pathogenesis of type 2 diabetes	6
Kilobase-scale genomic deletion of DOTFL1 in Dendrobium orchids	6
A REF6-dependent H3K27me3-depleted state facilitates gene activation during germination in Arabidopsis	6
Multiomics metabolic and epigenetics regulatory network in cancer: A systems biology perspective	6
A Bama miniature pig model of monoallelic TSC1 mutation for human tuberous sclerosis complex	6
Comprehensive lipidomics in apoM mice reveals an overall state of metabolic distress and attenuated hepatic lipid secretion into the circulation	6
Cyclin A2/cyclin-dependent kinase 1-dependent phosphorylation of Top2a is required for S phase entry during retinal development in zebrafish	6
Drosophila P75 safeguards oogenesis by preventing H3K9me2 spreading	6
Sox9+ cells are required for salivary gland regeneration after radiation damage via the Wnt/β-catenin pathway	6
Epigenome-Metabolome-Epigenome signaling cascade in cell biological processes	6
3D genome organization in the central nervous system, implications for neuropsychological disorders	6
Phosphorylation of Ago2 is required for its role in DNA double-strand break repair	6
Novel compound heterozygous variants in dynein axonemal heavy chain 17 cause asthenoteratospermia with sperm flagellar defects	6
Sequence motifs and prediction model of GBE editing outcomes based on target library analysis and machine learning	6
The synergistic role of Pu.1 and Fms in zebrafish osteoclast-reducing osteopetrosis and possible therapeutic strategies	6
Genomes of 12 fig wasps provide insights into the adaptation of pollinators to fig syconia	6
Genetic structure and domestication footprints of the tusk, coat color, and ear morphology in East Chinese pigs	6
Aberrant nuclear lamina contributes to the malignancy of human gliomas	6
Genetics of anorexia nervosa: An overview of genome-wide association studies and emerging biological links	6
G-quadruplexes in genomes of viruses infecting eukaryotes or prokaryotes are under different selection pressures from hosts	6
Genome-wide selection and introgression of Chinese rice varieties during breeding	6
Adrb1 and Adrb2b are the major β-adrenergic receptors regulating body axis straightening in zebrafish	6
LHCGR and ALMS1 defects likely cooperate in the development of polycystic ovary syndrome indicated by double-mutant mice	6
Peripheral and central control of obesity by primary cilia	6
The role of genotype and diet in shaping gut microbiome in a genetic vitamin A deficient mouse model	6
Molecular cytogenetic map visualizes the heterozygotic genome and identifies translocation chromosomes in Citrus sinensis	5
Functional analysis of the emerging roles for the KISS1/KISS1R signaling pathway in cancer metastasis	5
Untangling a complex web: Computational analyses of tumor molecular profiles to decode driver mechanisms	5
An instantaneous coalescent method insensitive to population structure	5
Alanine aminotransferase (OsAlaAT1) modulates nitrogen utilization, grain yield, and quality in rice	5
Defective arginine metabolism impairs mitochondrial homeostasis in Caenorhabditis elegans	5
Developmental regulation of neuronal gene expression by Elongator complex protein 1 dosage	5
Ancient Y-DNA with reconstructed phylogeny provides insights into the demographic history of paternal haplogroup N1a2-F1360	5
Long-term correction of hemophilia B through CRISPR/Cas9 induced homology-independent targeted integration	5
Juvenile hormone receptor Met regulates sleep and neuronal morphology via glial-neuronal crosstalk	5
The composition, function, and regulation of adipose stem and progenitor cells	5
Resident endothelial cells generate hepatocytes through cell fusion in adult mouse liver	5
Nuclear encoded elongation factor EF-Tu is required for chloroplast development in rice grown under low-temperature conditions	5
FISH-based “pan” and “core” karyotypes reveal genetic diversification of Roegneria ciliaris	5
Pathway analysis for genome-wide genetic variation data: Analytic principles, latest developments, and new opportunities	5
Loss of Wtap results in cerebellar ataxia and degeneration of Purkinje cells	5
Cdx1b protects intestinal cell fate by repressing signaling networks for liver specification	5
HPDL deficiency causes a neuromuscular disease by impairing the mitochondrial respiration	5
Deciphering the regulatory code of histone modifications in plants	5
Reproductive aging: biological pathways and potential interventive strategies	5
The transcription factor Sox30 is involved in Nile tilapia spermatogenesis	5
Maternal genetic history of southern East Asians over the past 12,000 years	5
Receptor-like kinase OsCR4 controls leaf morphogenesis and embryogenesis by fixing the distribution of auxin in rice	5
OsASHL1 and OsASHL2, two members of the COMPASS-like complex, control floral transition and plant development in rice	5
The evolution of sex chromosome dosage compensation in animals	5
Geranylgeranyl pyrophosphate-mediated protein geranylgeranylation regulates endothelial cell proliferation and apoptosis during vasculogenesis in mouse embryo	5
A recurrent mutation in TBPL2 causes diminished ovarian reserve and female infertility	5
The shikimate pathway regulates programmed cell death	5
Deciphering the evolution and complexity of wheat germplasm from a genomic perspective	5
Hsa_Circ_0000826 inhibits the proliferation of colorectal cancer by targeting AUF1	4
Reproductive tissue-specific translatome of a rice thermo-sensitive genic male sterile line	4
LIMK2 is required for membrane cytoskeleton reorganization of contracting airway smooth muscle	4
Nitric oxide-mediated S-nitrosylation of IAA17 protein in intrinsically disordered region represses auxin signaling	4
GRB10 regulates β-cell mass by inhibiting β-cell proliferation and stimulating β-cell dedifferentiation	4
Deletion of CHD8 in cerebellar granule neuron progenitors leads to severe cerebellar hypoplasia, ataxia, and psychiatric behavior in mice	4
Regulation of chloroplast protein degradation	4
FGF8-mediated signaling regulates tooth developmental pace during odontogenesis	4
Creating future crops: a revolution for sustainable agriculture	4
Lung stem cells in regeneration and tumorigenesis	4
OsMLH1 interacts with OsMLH3 to regulate synapsis and interference-sensitive crossover formation during meiosis in rice	4
Arabidopsis CAP1 mediates ammonium-regulated root hair growth by influencing vesicle trafficking and the cytoskeletal arrangement in root hair cells	4
The ZFP541-KCTD19 complex is essential for pachytene progression by activating meiotic genes during mouse spermatogenesis	4
Emerging roles of phosphoinositide-associated membrane trafficking in plant stress responses	4
Ancient DNA reveals the maternal genetic history of East Asian domestic pigs	4
Noninvasive preimplantation genetic testing in assisted reproductive technology: current state and future perspectives	4
A facile and sensitive method of quantifying glutaminase binding to its inhibitor CB-839 in tissues	4
Infection of SARS-CoV-2 causes severe pathological changes in mouse testis	4
Whole-genome sequences shed light on the demographic history and contemporary genetic erosion of free-ranging jaguar (Panthera onca) populations	4
Nucleolus-localized Def-CAPN3 protein degradation pathway and its role in cell cycle control and ribosome biogenesis	4
Maternal genetic history of ancient Tibetans over the past 4000 years	4
Improving the Cpf1-mediated base editing system by combining dCas9/dead sgRNA with human APOBEC3A variants	4
Deciphering the chromatin spatial organization landscapes during BMMSC differentiation	4
Phosphatidylinositol 4-kinase β mutations cause nonsyndromic sensorineural deafness and inner ear malformation	4
Antibody upstream sequence diversity and its biological implications revealed by repertoire sequencing	4
Genomic and transcriptomic analyses enable the identification of important genes associated with subcutaneous fat deposition in Holstein cows	4
Key regulators of intestinal stem cells: diet, microbiota, and microbial metabolites	3
Mycobacterium Lrp/AsnC family transcriptional factor modulates the arginase pathway as both a sensor and a transcriptional repressor	3
Targeted lipidomics reveals plasmalogen phosphatidylethanolamines and storage triacylglycerols as the major systemic lipid aberrations in Bietti crystalline corneoretinal dystrophy	3
Identification of CHMP4C as a new risk gene for inherited dilated cardiomyopathy	3
Adenocarcinoma transformed into squamous cell carcinoma in non-small cell lung cancer	3