Neural Regeneration Research

Article	Citations
Generating oligodendroglia from adult mesenchymal cells for transplantation: cell reprogramming or direct lineage conversion?	247
Increased retinal venule diameter as a prognostic indicator for recurrent cerebrovascular events: a prospective observational study	169
SCFD1 in amyotrophic lateral sclerosis: reconciling a genetic association with in vivo functional analysis	114
Protocadherin gamma C3: a new player in regulating vascular barrier function	107
Rapamycin as a preventive intervention for Alzheimer’s disease in APOE4 carriers: Targeting brain metabolic and vascular restoration	101
Tropism-shifted AAV-PHP.eB-mediated bFGF gene therapy promotes varied neurorestoration after ischemic stroke in mice	101
Beyond apoptosis: Implications of annexin-V binding to myeloid cells in DARC (Detection of Apoptosing Retinal Cells) imaging	99
Delayed microglial depletion protects against white matter injury following neonatal cerebral hemorrhage in mice	88
Telomere length as a predictive marker for long-term cognitive function in a mouse model of subarachnoid hemorrhage	81
The intrinsic excitability of and autophagy protein expression levels in dentate gyrus ensembles regulate fear generalization	80
FKBP51: A new target for Parkinson’s disease	78
Intriguing role of the Golgi apparatus in astrocyte function: Implications for disorders	74
Decoding molecular mechanisms: brain aging and Alzheimer’s disease	73
Metformin promotes angiogenesis and functional recovery in aged mice after spinal cord injury by adenosine monophosphate-activated protein kinase/endothelial nitric oxide synthase pathway	73
Activity-dependent regulation of cortical cell numbers: Role of neuronal activity in cortical circuit formation	73
Glycine decarboxylase as a novel regulator of N-methyl-D-aspartate receptor function: Implications for pathophysiology of schizophrenia	70
Ethanol changes Nestin-promoter induced neural stem cells to disturb newborn dendritic spine remodeling in the hippocampus of mice	67
Injectable collagen scaffold with human umbilical cord-derived mesenchymal stem cells promotes functional recovery in patients with spontaneous intracerebral hemorrhage: phase I clinical trial	65
Activation of medial septum cholinergic neurons restores cognitive function in temporal lobe epilepsy	65
Functions of nuclear factor Y in nervous system development, function and health	65
Chx10+V2a interneurons in spinal motor regulation and spinal cord injury	61
Astrocyte chloride, excitatory-inhibitory balance and epilepsy	61
Phosphorylation-driven aggregative proteins in neurodegenerative diseases: implications and therapeutics	60
Could inorganic polyphosphate be a valid target against neuronal senescence?	60
Exercise-with-melatonin therapy improves sleep disorder and motor dysfunction in a rat model of ischemic stroke	59

Human endogenous retrovirus type-W and multiple sclerosis–related smoldering neuroinflammation	59
Dual-targeting AAV9P1-mediated neuronal reprogramming in a mouse model of traumatic brain injury	58
Neuropsychiatric symptoms and apolipoprotein E genotypes in neurocognitive disorders	57
Liposomes as versatile agents for the management of traumatic and nontraumatic central nervous system disorders: drug stability, targeting efficiency, and safety	56
Clemastine in remyelination and protection of neurons and skeletal muscle after spinal cord injury	55
Mitochondrial transplantation: a promising strategy for the treatment of retinal degenerative diseases	55
Multiple factors to assist human-derived induced pluripotent stem cells to efficiently differentiate into midbrain dopaminergic neurons	54
Functional near-infrared spectroscopy in non-invasive neuromodulation	54
Stepping up after spinal cord injury: negotiating an obstacle during walking	54
Prolonged intermittent theta burst stimulation restores the balance between A2AR- and A1R-mediated adenosine signaling in the 6-hydroxidopamine model of Parkinson’s disease	54
Eph receptor A4 regulates motor neuron ferroptosis in spinal cord ischemia/reperfusion injury in rats	53
Krüppel-like factor 2 (KLF2), a potential target for neuroregeneration	52
NECAB family of neuronal calcium-binding proteins in health and disease	52
Targeting tau in Alzheimer's disease: from mechanisms to clinical therapy	51
Mesenchymal stem cell–derived small extracellular vesicles promote mitochondrial repair of dopaminergic neurons via Homer protein homolog 3 in Parkinson's disease	51
The circ_0002538/miR-138-5p/plasmolipin axis regulates Schwann cell migration and myelination in diabetic peripheral neuropathy	50
Neuromodulation techniques for modulating cognitive function: Enhancing stimulation precision and intervention effects	50
Autolysosomal acidification impairment as a mediator for TNFR1 induced neuronal necroptosis in Alzheimer's disease	50
Porcine decellularized nerve matrix hydrogel attenuates neuroinflammation after peripheral nerve injury by inhibiting the TLR4/MyD88/NF-κB axis	49
Small extracellular vesicles secreted by induced pluripotent stem cell-derived mesenchymal stem cells improve postoperative cognitive dysfunction in mice with diabetes	49
LL-37 and CsgC exemplify the crosstalk between anti-amyloid, antimicrobial, and anti-biofilm protein activities	49
Mitochondrial dynamics dysfunction and neurodevelopmental disorders: From pathological mechanisms to clinical translation	48
Role of the globus pallidus in motor and non-motor symptoms of Parkinson’s disease	48
Mesenchymal stem cell-derived extracellular vesicles therapy in traumatic central nervous system diseases: a systematic review and meta-analysis	47
Peripheral mitochondrial DNA as a neuroinflammatory biomarker for major depressive disorder	47
Potential common pathogenesis of several neurodegenerative diseases	47
Neuroserpin alleviates cerebral ischemia-reperfusion injury by suppressing ischemia-induced endoplasmic reticulum stress	46
Neurogenesis dynamics in the olfactory bulb: deciphering circuitry organization, function, and adaptive plasticity	46
Role of copper chelating agents: between old applications and new perspectives in neuroscience	46
Rbm8a regulates neurogenesis and reduces Alzheimer’s disease-associated pathology in the dentate gyrus of 5×FAD mice	46
Enhancement of lysosome biogenesis as a potential therapeutic approach for neurodegenerative diseases	45
The complex roles of m6A modifications in neural stem cell proliferation, differentiation, and self-renewal and implications for memory and neurodegenerative diseases	45
Endorepellin downregulation promotes angiogenesis after experimental traumatic brain injury	43
Amyloid-beta and tau protein beyond Alzheimer’s disease	43
Selective deletion of zinc transporter 3 in amacrine cells promotes retinal ganglion cell survival and optic nerve regeneration after injury	43
Premature axon-oligodendrocyte interaction contributes to stalling of experimental axon regeneration after injury to the white matter	42
Dynamic regulation of the developmental establishment of the adult hippocampal neural stem cell pool	42
Interferon regulatory factor 1 enhances T cell differentiation in patients with myasthenia gravis	41
Role of calcium homeostasis in retinal ganglion cell degeneration	41
Regulatory role of neuronal guidance proteins in spinal cord injury	41
The roles of microglia and astrocytes in inflammasomes and neurological disorders	41
Advances in non-invasive imaging of proteinopathies in animal models of neurodegenerative diseases	40
Amyloid degradation mechanisms and potential synergistic effects	40
Utility of droplet digital polymerase chain reaction for studying somatic mosaicism: brain malformations and beyond	40
Blocking postsynaptic density-93 binding to C-X3-C motif chemokine ligand 1 promotes microglial phenotypic transformation during acute ischemic stroke	40
Targeting muscle to treat Charcot-Marie-Tooth disease	39
Insights from an academic endeavor into central nervous system drug discovery	39
Converging assemblies: A putative building block for brain function and for interfacing with the brain	39
On the functions of astrocyte-mediated neuronal slow inward currents	39
Therapeutic effects of low-intensity transcranial focused ultrasound stimulation on ischemic stroke in rats: An in vivo evaluation using electrical impedance tomography	39

Application of artificial intelligence for the prediction of amyloidoses	38
Unraveling the role of ufmylation in the brain	38
Sex modulates the outcome of subthalamic nucleus deep brain stimulation in patients with Parkinson’s disease	38
Multimodal MRI combined with RNA sequencing reveals pathological signatures in the 9-month-old 3×Tg-AD mouse brain	38
Neurodegeneration-induced angioarchitecture remodeling	38
The neuroprotective effects of oxygen therapy in Alzheimer’s disease: a narrative review	38
Exacerbation of neuronal senescence after spinal cord injury: Role of the macrophage-derived transforming growth factor-β1–SMAD2 signaling axis	38
Delta-opioid receptor–mediated neural protection and regeneration	38
Neurodevelopmental defects as a primer of neurodegeneration: lessons from spinal muscular atrophy and Huntington’s disease	38
Treating dysfunctional one-carbon metabolism in glaucoma	38
Small extracellular vesicles derived from cerebral endothelial cells with elevated microRNA 27a promote ischemic stroke recovery	37
Targeting sigma receptors for Alzheimer’s disease treatment	37
New insights on the role of chondroitin sulfate proteoglycans in neural stem cell–mediated repair in spinal cord injury	37
Modulation of the excitation/inhibition balance by astrocytes in a tripartite synapse model of Alzheimer's disease	37
Retraction: Ultrasound guided neural stem cell transplantation through the lateral ventricle for treatment of cerebral palsy in children	37
Exploring the novel role of oligodendrocyte precursor cells in phagocytosis: beyond myelinogenesis	36
Pharmacological interventions targeting the microcirculation following traumatic spinal cord injury	36
Extracellular vesicles: multiple signaling capabilities and translation into promising therapeutic targets to promote neuronal plasticity	36
M2 macrophages mediate fibrotic scar formation in the early stages after cerebral ischemia in rats	36
Exercise training promotes nerve cell repair and regeneration after spinal cord injury	35
Newfound physiological function of FAIM protein offers hope of novel disease-modifying therapy for Alzheimer’s disease	35
Exploration of C-terminal CX3CL1 for reducing age-dependent neurodegeneration	35
Argatroban promotes recovery of spinal cord injury by inhibiting the PAR1/JAK2/STAT3 signaling pathway	35
Artificial intelligence and peripheral neuropathies: Strategies for the development, application, and repair of regenerative biomaterials	35
Biochanin A attenuates spinal cord injury in rats during early stages by inhibiting oxidative stress and inflammasome activation	35
Crosstalk among canonical Wnt and Hippo pathway members in skeletal muscle and at the neuromuscular junction	35
A core scientific problem in the treatment of central nervous system diseases: newborn neurons	35
NLRP3/1-mediated pyroptosis: beneficial clues for the development of novel therapies for Alzheimer’s disease	34
Neuroprotection provided by polyphenols and flavonoids in photoreceptor degenerative diseases	34
Utilizing engineered extracellular vesicles as delivery vectors in the management of ischemic stroke: a special outlook on mitochondrial delivery	34
Inducing prion protein shedding as a neuroprotective and regenerative approach in pathological conditions of the brain: from theory to facts	34
Prediction of cell-cell communication patterns of dorsal root ganglion cells: single-cell RNA sequencing data analysis	34
Amyotrophic lateral sclerosis disease burden: doing better at getting better	34
Cerebral organoids as a platform to model prenatal exposure to drugs of abuse	33
Treatment with β-sitosterol ameliorates the effects of cerebral ischemia/reperfusion injury by suppressing cholesterol overload, endoplasmic reticulum stress, and apoptosis	33
Dysfunction of synaptic endocytic trafficking in Parkinson’s disease	33
Post-acute ischemic stroke hyperglycemia aggravates destruction of the blood-brain barrier	33
Secretase inhibition in Alzheimer’s disease therapeutics reveals functional roles of amyloid-beta42	33
Bidirectional communication between the gut microbiota and the central nervous system	33
Prospect in Alzheimer’s disease integrative therapy targeting both amyloid-beta and tau	33
The secondary injury cascade after spinal cord injury: an analysis of local cytokine/chemokine regulation	33
Inhibition of Raly promotes oligodendrocyte precursor cell differentiation and remyelination after chronic hypoperfusion	33
New aspects of a small GTPase RAB35 in brain development and function	33
Blood-brain barrier pathology in cerebral small vessel disease	33
Advances and unmet needs in fluid and tissue biomarkers in Parkinson’s disease	33
Modulation of p75 neurotrophin receptor mitigates brain damage following ischemic stroke in mice	33
Erythropoietin inhibits ferroptosis and ameliorates neurological function after spinal cord injury	33
New insights into the role of the endoplasmic reticulum in microglia	33
Effects of quercetin and its derivatives in in vivo models of neuroinflammation: A systematic review and meta-analysis	33
A review of the neurotransmitter system associated with cognitive function of the cerebellum in Parkinson’s disease	33
Imaging mass spectrometry: a molecular microscope for studying the role of lipids in Parkinson’s disease	32
Making bridges between preclinical and clinical insights into age-related cognitive decline	32
Basic fibroblast growth factor sustained-release system promotes neurogenesis and tissue repair after spinal cord injury	32
Mechanosensitive Piezo1 channel regulation of microglial cell function and implications to neurodegenerative diseases and neuroinflammation	32
Heterogeneity of mature oligodendrocytes in the central nervous system	32
Neuronal chemokines: new insights into neuronal communication after injury	32
Contribution of glial cells to the neuroprotective effects triggered by repetitive magnetic stimulation	32
Artificial nerve graft constructed by coculture of activated Schwann cells and human hair keratin for repair of peripheral nerve defects	32
Fasudil-modified macrophages reduce inflammation and regulate the immune response in experimental autoimmune encephalomyelitis	32
Bioactive material promotes long-distance regeneration of optic nerve to restore visual functions	32
The critical role of the endolysosomal system in cerebral ischemia	32
Carboplatin restores neuronal toxicity in FUS-linked amyotrophic lateral sclerosis	32
Tau’s function and dysfunction in the brain	31
Data and subject heterogeneity and data sharing: keys to translational success in spinal cord injury research?	31
Transcranial photobiomodulation for the brain: a wide range of clinical applications	31
Two become one: combination of two risk factors in a new glaucoma animal model	31
Potential role of cytosolic PTEN-induced kinase 1 in facilitating proteaphagy	31
Neural and Müller glial adaptation of the retina to photoreceptor degeneration	31
Anti-vascular endothelial growth factor drugs combined with laser photocoagulation maintain retinal ganglion cell integrity in patients with diabetic macular edema: study protocol for a prospective, n	31
Neuronal autosis: the self-destructive side of autophagy involved in hypoxic-ischemic neuronal death	31
Letter from the Editor-in-Chief	31
Implication of gut microbiome in age-related macular degeneration	30
Adipose mesenchymal stem cell-derived extracellular vesicles reduce glutamate-induced excitotoxicity in the retina	30
Genetic and pathway complexity in Alzheimer’s disease: Insights from multi-omic data about the immune response and mitochondrial function	30
Low-intensity transcranial ultrasound neuromodulation promotes neuronal regeneration: A new hope for noninvasive treatment of neurodegenerative diseases	30
Multiple sclerosis drug repurposing for neuroregeneration	30
Targeting the dopaminergic midbrain in Alzheimer’s disease: Therapeutic potential of focusing on specific neural circuits rather than single molecular pathways	30
Adipocytes and macrophages after stroke: Interactions between metabolism and immunity	30
Post-transcriptional mechanisms controlling neurogenesis and direct neuronal reprogramming	30
Clues from a missense mutation of the adenosine A1 receptor gene associated with early-onset Parkinson’s disease	30

Metformin remodels the myelin landscape	29
Insights into the transcriptomic heterogeneity of brain endothelial cells in normal aging and Alzheimer’s disease	29
5-Hydroxytryptamine: a potential therapeutic target in amyotrophic lateral sclerosis	29
Differential distribution of PINK1 and Parkin in the primate brain implies distinct roles	29
Oxidative stress in retinal pigment epithelium degeneration: from pathogenesis to therapeutic targets in dry age-related macular degeneration	29
Interconnections between diabetic corneal neuropathy and diabetic retinopathy: diagnostic and therapeutic implications	29
Magnesium-L-threonate treats Alzheimer’s disease by modulating the microbiota-gut-brain axis	29
Microglial depletion impairs glial scar formation and aggravates inflammation partly by inhibiting STAT3 phosphorylation in astrocytes after spinal cord injury	28
Intranasal therapies for neonatal hypoxic-ischemic encephalopathy	28
Emerging roles of astrocytes in blood-brain barrier disruption upon amyloid-beta insults in Alzheimer’s disease	28
Stiffness-tunable biomaterials provide a good extracellular matrix environment for axon growth and regeneration	28
High-dose biotin neither fosters remyelination nor stimulates malonyl coenzyme A synthesis in the regenerating nerve	28
The effects and potential of microglial polarization and crosstalk with other cells of the central nervous system in the treatment of Alzheimer’s disease	28
Biomaterial-based strategies: a new era in spinal cord injury treatment	28
Targeting autophagy by polyphenols to prevent glycative stress-toxicity in the brain	28
Brain injury after subarachnoid hemorrhage: Glymphatic contributions	27
Taurine: a promising nutraceutic in the prevention of retinal degeneration	27
Stable isotope labeling-mass spectrometry as a new approach to determine remyelination	27
Retraction: Resveratrol inhibits matrix metalloproteinases to attenuate neuronal damage in cerebral ischemia: a molecular docking study exploring possible neuroprotection	27
Magnetic resonance imaging focused on the ferritin heavy chain 1 reporter gene detects neuronal differentiation in stem cells	27
Strategies to treat neurodegeneration in neuronal ceroid lipofuscinosis: a view onto the retina	27
Grafts of hydrogel-embedded electrically stimulated subventricular stem cells into the stroke cavity improves functional recovery of mice	27
Synaptic pathology in multiple sclerosis: a role for Nogo-A signaling in astrocytes?	27
Protein disulfide isomerases in amyotrophic lateral sclerosis: Endoplasmic reticulum proteostasis and neuromuscular function	27
Multifaceted superoxide dismutase 1 expression in amyotrophic lateral sclerosis patients: a rare occurrence?	27
Brain-penetrating neurotrophic factor mimetics: HER-096 as a disease-modifying therapy for Parkinson’s disease	27
In vivo measures of glutamate and the excitation/inhibition imbalance in brain disorders	27
Renin-angiotensin system in the central nervous system: focus on Huntington’s disease	27
Restarting synaptic remodeling and structural network: New treatment strategies for epilepsy	27
Unexpected role of complement component 8 gamma chain in the inflamed brain	27
Iron-handling solute carrier SLC22A17 as a blood–brain barrier target after stroke	26
Detection of white matter microstructural changes in patients with systemic lupus erythematosus based on multiple diffusion models and related diffusion metrics	26
MAPT-isoform 0N3R is essential for human brain development: Loss-of-function for novel TAU-associated disease paradigms	26
C–C motif chemokine ligand 2/C–C motif chemokine receptor 2 pathway as a therapeutic target and regulatory mechanism for spinal cord injury	26
Integrated multi-omics and machine learning identify Casp8 and Pycard as central regulators of pyroptosis and necroptosis in spinal cord injury	26
Remaking a connection: molecular players involved in post-injury synapse formation	26
Alpha-synuclein-induced upregulation of SKI family transcriptional corepressor 1: A new player in aging and Parkinson’s disease?	26
Rethinking microglia from a circadian perspective in neuroimmunology: New insights	26
Transplantation of human neural stem cells repairs neural circuits and restores neurological function in the stroke-injured brain	26
Establishing a role of the insulin receptor in microglia	26
Transcriptomic and morphological characterization reveals distinct regeneration kinetics in immediate versus delayed nerve repair	26
Brain organoids and genome editing: A new era in understanding human brain development and disorders	26
Targeting the NLRP3–NEK7 axis with rebamipide: Drug repurposing in Parkinson’s disease	26
Exosomes in stroke management: A promising paradigm shift in stroke therapy	26
MET receptor tyrosine kinase promotes the generation of functional synapses in adult cortical circuits	26
Fibrinogen’s potential role in connecting cerebrovascular abnormalities with glymphatic dysfunction in Alzheimer’s disease	26
Electroactive hydrogel with human umbilical cord mesenchymal stem cell–derived exosomes remodels the microenvironment of spinal cord lesion sites and rebuilds neural circuits after injury	26
Extracellular vesicles for neural regeneration after spinal cord injury	26
Exploring the synergy of the eye-brain connection: neuromodulation approaches for neurodegenerative disorders through transcorneal electrical stimulation	26
Sex differences in Alzheimer’s disease: an urgent research venue to follow	25
Actin(g) toward a revised understanding of the role of cytoskeletal dynamics in neuronal bioenergetics	25
Retinal glial cells in glaucoma and age-related retinal diseases: Inflammatory responses, disease transitions, and translational perspectives	25
Beyond wrecking a wall: revisiting the concept of blood–brain barrier breakdown in ischemic stroke	25
MicroRNA and Alzheimer’s disease: Diagnostic biomarkers and potential therapeutic targets	25
Gut microbiota dysbiosis contributes to α-synuclein-related pathology associated with C/EBPβ/AEP signaling activation in a mouse model of Parkinson's disease	25
Molecular mechanisms after optic nerve injury: Neurorepair strategies from a transcriptomic perspective	25
Combined cell-based therapy strategies for the treatment of Parkinson’s disease: focus on mesenchymal stromal cells	25
Targeting interleukin-6 trans-signaling to improve post-stroke inflammation: A precision immunotherapy perspective	25
Proteostasis decline and endoplasmic reticulum stress in aging: Implications for cellular senescence and senescence-associated secretory phenotype regulation	25
cGAS–STING pathway modulation: A new hope for neural regeneration	25
Antisense oligonucleotides provide optimism to the therapeutic landscape for tauopathies	25
Rebuilding insight into the pathophysiology of Alzheimer's disease through new blood-brain barrier models	25
Ischemic accumulation of succinate induces Cdc42 succinylation and inhibits neural stem cell proliferation after cerebral ischemia/reperfusion	25
Blood-based biomarkers and early diagnosis of Alzheimer’s disease	25
Intranasal nerve growth factor for prevention and recovery of the outcomes of traumatic brain injury	25
Mitochondrial therapeutics and mitochondrial transfer for neurodegenerative diseases and aging	25
Low-density lipoprotein receptor–related protein 1 mediates α-synuclein transmission from the striatum to the substantia nigra in animal models of Parkinson’s disease	24
Correlation between the gut microbiome and neurodegenerative diseases: a review of metagenomics evidence	24
Astrocyte evolution and human specificity	24
Blockade of Rho-associated kinase prevents inhibition of axon regeneration of peripheral nerves induced by anti-ganglioside antibodies	24
Neuronal plasticity and its role in Alzheimer’s disease and Parkinson’s disease	24
Inflammation and retinal degenerative diseases	24
New unexpected role for Wolfram Syndrome protein WFS1: a novel therapeutic target for Alzheimer’s disease?	24
Pathophysiological changes of muscle after ischemic stroke: a secondary consequence of stroke injury	24
Inhibitory gamma-aminobutyric acidergic neurons in the anterior cingulate cortex participate in the comorbidity of pain and emotion	24
Ferroptosis mechanism and Alzheimer's disease	24
Secretory autophagy in neurons: More than throwing out the trash?	24
Anoctamin 4 defines glucose-inhibited neurons in the ventromedial hypothalamus	24
Persistent alterations in gray matter in COVID-19 patients experiencing sleep disturbances: a 3-month longitudinal study	24
Analysis of the dual role of amyloid-beta in Alzheimer’s disease through multi-omics integration	24
Neuroinflammation revisited through the microglial lens	24
Reviving the use of inhibitors of matrix metalloproteases in spinal cord injury: a case for specificity	23
Short-lived Niemann-Pick type C mice with accelerated brain aging as a novel model for Alzheimer’s disease research	23
RNA sequencing of exosomes secreted by fibroblast and Schwann cells elucidates mechanisms underlying peripheral nerve regeneration	23
Regulation of aging by NELF-A and RNA polymerase II elongation	23
Could mammalian inorganic polyphosphate be a crucial signaling molecule in neurological disorders?	23
ABCA5 lipid transporter is associated with a reduced risk of Parkinson’s disease	23
Small extracellular vesicles derived from hair follicle neural crest stem cells enhance perineurial cell proliferation and migration via the TGF-β/SMAD/HAS2 pathway	23
Deconvolution in Alzheimer’s disease	23
Cholinergic pathways in neural stem cell regulation and glioblastoma progression: Shared origins and mechanisms	23
Nuance of inward rectifying potassium (Kir) channel dysfunctions in neurodegenerative diseases	23
Animal models of vascularized nerve grafts: a systematic review	23
Dual role of fibroblasts in fibrous scar formation after spinal cord injury: Single-cell sequencing and experimental verification	23
Techniques and factors for reducing chronic neuropathic pain: A review	23
Mechanisms underlying neuroimmune networks as central regulators in combating neurodegenerative diseases	23