Neural Regeneration Research

(The TQCC of Neural Regeneration Research is 7. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-04-01 to 2024-04-01.)
Microglia regulation of synaptic plasticity and learning and memory154
Pathological mechanisms and therapeutic strategies for Alzheimer’s disease146
Amyloid-beta peptide and tau protein crosstalk in Alzheimer’s disease86
Oxidative stress factors in Parkinson’s disease82
Liproxstatin-1 is an effective inhibitor of oligodendrocyte ferroptosis induced by inhibition of glutathione peroxidase 480
Astrocytes: a double-edged sword in neurodegenerative diseases75
Promising drug targets and associated therapeutic interventions in Parkinson’s disease73
Research trends, hot spots and prospects for necroptosis in the field of neuroscience68
Microglia-associated neuroinflammation is a potential therapeutic target for ischemic stroke66
Do pyroptosis, apoptosis, and necroptosis (PANoptosis) exist in cerebral ischemia? Evidence from cell and rodent studies62
Microglia in neurodegenerative diseases59
Exosomes derived from bone marrow mesenchymal stem cells protect the injured spinal cord by inhibiting pericyte pyroptosis51
Apelin-13 inhibits apoptosis and excessive autophagy in cerebral ischemia/reperfusion injury50
The emerging role of probiotics in neurodegenerative diseases: new hope for Parkinson’s disease?48
Targeting the core of neurodegeneration: FoxO, mTOR, and SIRT145
Mesenchymal stem cell treatment for peripheral nerve injury: a narrative review45
Targeting neuroinflammation in Alzheimer’s disease: from mechanisms to clinical applications41
Potential effects of mesenchymal stem cell derived extracellular vesicles and exosomal miRNAs in neurological disorders40
Lineage tracing of direct astrocyte-to-neuron conversion in the mouse cortex40
Association between inflammatory bowel diseases and Parkinson’s disease: systematic review and meta-analysis39
Inflammation in diabetic retinopathy: possible roles in pathogenesis and potential implications for therapy38
Mitochondrial dysfunctions in neurodegenerative diseases: role in disease pathogenesis, strategies for analysis and therapeutic prospects38
Mechanisms of neuroplasticity and brain degeneration: strategies for protection during the aging process38
Inflammation induces zebrafish regeneration36
A multi-channel collagen scaffold loaded with neural stem cells for the repair of spinal cord injury36
Ferroptosis: a critical player and potential therapeutic target in traumatic brain injury and spinal cord injury35
Basic mechanisms of peripheral nerve injury and treatment via electrical stimulation35
Mechanism underlying treatment of ischemic stroke using acupuncture: transmission and regulation35
Cortical plasticity and nerve regeneration after peripheral nerve injury34
The NLRP3 inflammasome: a potential therapeutic target for traumatic brain injury34
Oral frailty and neurodegeneration in Alzheimer’s disease32
The future of retinal gene therapy: evolving from subretinal to intravitreal vector delivery32
Interaction between Schwann cells and other cells during repair of peripheral nerve injury31
Role of exosomes in the pathogenesis of inflammation in Parkinson’s disease31
Prospects for intelligent rehabilitation techniques to treat motor dysfunction31
Electroacupuncture improves learning and memory functions in a rat cerebral ischemia/reperfusion injury model through PI3K/Akt signaling pathway activation31
Progress in clinical trials of cell transplantation for the treatment of spinal cord injury: how many questions remain unanswered?30
SARS-CoV-2 involvement in central nervous system tissue damage30
Abnormal characterization of dynamic functional connectivity in Alzheimer’s disease30
The Yin-Yang of osteopontin in nervous system diseases: damage versus repair29
Regulation of neuroimmune processes by damage- and resolution-associated molecular patterns29
Therapeutic potential of trehalose in neurodegenerative diseases: the knowns and unknowns29
Liposome based drug delivery as a potential treatment option for Alzheimer’s disease28
Delving into the recent advancements of spinal cord injury treatment: a review of recent progress28
Quercetin protects against diabetic retinopathy in rats by inducing heme oxygenase-1 expression28
TP53-induced glycolysis and apoptosis regulator alleviates hypoxia/ischemia-induced microglial pyroptosis and ischemic brain damage28
The interaction of stem cells and vascularity in peripheral nerve regeneration28
Low-dose lipopolysaccharide as an immune regulator for homeostasis maintenance in the central nervous system through transformation to neuroprotective microglia28
Microglia activation, classification and microglia-mediated neuroinflammatory modulators in subarachnoid hemorrhage28
Neural stem cell-derived exosome as a nano-sized carrier for BDNF delivery to a rat model of ischemic stroke27
P2X7 receptor activation aggravates NADPH oxidase 2-induced oxidative stress after intracerebral hemorrhage27
Urolithin A alleviates blood-brain barrier disruption and attenuates neuronal apoptosis following traumatic brain injury in mice27
PANoptosis-like cell death in ischemia/reperfusion injury of retinal neurons27
Deciphering the role of PGC-1α in neurological disorders: from mitochondrial dysfunction to synaptic failure27
Epidural electrical stimulation for spinal cord injury27
Pro- and anti-epileptic roles of microglia26
Chronic peripheral inflammation: a possible contributor to neurodegenerative diseases26
Physiopathology of ischemic stroke and its modulation using memantine: evidence from preclinical stroke26
Regulation of neuronal bioenergetics as a therapeutic strategy in neurodegenerative diseases26
Potential therapeutic effects of polyphenols in Parkinson's disease: in vivo and in vitro pre-clinical studies26
Application of modern neuroimaging technology in the diagnosis and study of Alzheimer's disease26
Motor tract reorganization after acute central nervous system injury: a translational perspective25
The relationship between amyloid-beta and brain capillary endothelial cells in Alzheimer’s disease25
Insights into stem cell therapy for diabetic retinopathy: a bibliometric and visual analysis25
Potential neuroprotection by Dendrobium nobile Lindl alkaloid in Alzheimer’s disease models25
LncRNA Airsci increases the inflammatory response after spinal cord injury in rats through the nuclear factor kappa B signaling pathway25
Maraviroc promotes recovery from traumatic brain injury in mice by suppression of neuroinflammation and activation of neurotoxic reactive astrocytes25
Progress in clinical trials of stem cell therapy for cerebral palsy25
Efficacy and safety of transcutaneous auricular vagus nerve stimulation combined with conventional rehabilitation training in acute stroke patients: a randomized controlled trial conducted for 1 year 24
Parkinson’s disease and diabetes mellitus: common mechanisms and treatment repurposing24
The secretome of endothelial progenitor cells: a potential therapeutic strategy for ischemic stroke24
Spinal cord injury-induced cognitive impairment: a narrative review24
Survivors of COVID-19 exhibit altered amplitudes of low frequency fluctuation in the brain: a resting-state functional magnetic resonance imaging study at 1-year follow-up24
Graphene oxide-composited chitosan scaffold contributes to functional recovery of injured spinal cord in rats24
Role of vitamin B12 deficiency in ischemic stroke risk and outcome24
Current application and future directions of photobiomodulation in central nervous diseases24
Phytochemicals as inhibitors of tumor necrosis factor alpha and neuroinflammatory responses in neurodegenerative diseases23
Initial failures of anti-tau antibodies in Alzheimer’s disease are reminiscent of the amyloid-β story23
Enriched environment boosts the post-stroke recovery of neurological function by promoting autophagy23
Hyperglycemia in acute ischemic stroke: physiopathological and therapeutic complexity23
Emerging blood exosome-based biomarkers for preclinical and clinical Alzheimer’s disease: a meta-analysis and systematic review23
Astrocytes protect dopaminergic neurons against aminochrome neurotoxicity23
Neutrophil-to-lymphocyte ratio in sporadic amyotrophic lateral sclerosis23
Neuroregeneration and functional recovery after stroke: advancing neural stem cell therapy toward clinical application23
Application of neurotrophic and proangiogenic factors as therapy after peripheral nervous system injury22
Exosomes derived from bone marrow mesenchymal stem cells inhibit neuroinflammation after traumatic brain injury22
Repetitive transcranial magnetic stimulation for lower extremity motor function in patients with stroke: a systematic review and network meta-analysis22
Axonal regeneration and sprouting as a potential therapeutic target for nervous system disorders22
Adipose tissue, systematic inflammation, and neurodegenerative diseases22
Retinal regeneration requires dynamic Notch signaling22
Circulating extracellular vesicles: friends and foes in neurodegeneration22
GDNF to the rescue: GDNF delivery effects on motor neurons and nerves, and muscle re-innervation after peripheral nerve injuries22
Repurposed anti-cancer epidermal growth factor receptor inhibitors: mechanisms of neuroprotective effects in Alzheimer’s disease22
Rapid GFAP and Iba1 expression changes in the female rat brain following spinal cord injury21
Inhibition of LncRNA Vof-16 expression promotes nerve regeneration and functional recovery after spinal cord injury21
Diabetes mellitus and Parkinson’s disease: dangerous liaisons between insulin and dopamine21
Analysis of corneal nerve plexus in corneal confocal microscopy images21
Degenerative and regenerative processes in amyotrophic lateral sclerosis: motor reserve, adaptation and putative compensatory changes21
Cognitive impairment in multiple sclerosis: lessons from cerebrospinal fluid biomarkers21
Baicalin attenuates blood-spinal cord barrier disruption and apoptosis through PI3K/Akt signaling pathway after spinal cord injury21
Glucagon-like peptide-1/glucose-dependent insulinotropic polypeptide dual receptor agonist DA-CH5 is superior to exendin-4 in protecting neurons in the 6-hydroxydopamine rat Parkinson model21
Corneal neuromediator profiles following laser refractive surgery21
Role of apoptosis-inducing factor in perinatal hypoxic-ischemic brain injury21
Neuronal reprogramming in treating spinal cord injury21
Lithium beyond psychiatric indications: the reincarnation of a new old drug21
Lycium barbarum polysaccharide-glycoprotein preventative treatment ameliorates aversive21
VX-765 reduces neuroinflammation after spinal cord injury in mice20
Exosomal miR-23b from bone marrow mesenchymal stem cells alleviates oxidative stress and pyroptosis after intracerebral hemorrhage20
Neuroinflammation as a mechanism linking hypertension with the increased risk of Alzheimer’s disease20
Diabetic corneal neuropathy as a surrogate marker for diabetic peripheral neuropathy20
Collagen/heparan sulfate porous scaffolds loaded with neural stem cells improve neurological function in a rat model of traumatic brain injury20
Hydrogel-based local drug delivery strategies for spinal cord repair20
Toward three-dimensional in vitro models to study neurovascular unit functions in health and disease20
Brain-derived neurotrophic factor and its related enzymes and receptors play important roles after hypoxic-ischemic brain damage20
Ultrasonic vocalizations in mice: relevance for ethologic and neurodevelopmental disorders studies20
The influence of gut microbiota alteration on age-related neuroinflammation and cognitive decline20
The use of hydrogel-delivered extracellular vesicles in recovery of motor function in stroke: a testable experimental hypothesis for clinical translation including behavioral and neuroimaging assessme20
Temporal changes in inflammatory mitochondria-enriched microRNAs following traumatic brain injury and effects of miR-146a nanoparticle delivery20
Exploration of the mechanism by which icariin modulates hippocampal neurogenesis in a rat model of depression19
The “mitochondrial stress responses”: the “Dr. Jekyll and Mr. Hyde” of neuronal disorders19
Hypoxia in Alzheimer's disease: effects of hypoxia inducible factors19
Neuroimaging mechanisms of high-frequency repetitive transcranial magnetic stimulation for treatment of amnestic mild cognitive impairment: a double-blind randomized sham-controlled trial19
Microglial depletion impairs glial scar formation and aggravates inflammation partly by inhibiting STAT3 phosphorylation in astrocytes after spinal cord injury19
Phosphorylated tau as a toxic agent in synaptic mitochondria: implications in aging and Alzheimer’s disease19
Neuroprotective effects of naturally sourced bioactive polysaccharides: an update19
Down-regulating Circular RNA Prkcsh suppresses the inflammatory response after spinal cord injury19
Connexin therapeutics: blocking connexin hemichannel pores is distinct from blocking pannexin channels or gap junctions19
Interleukin-4 promotes microglial polarization toward a neuroprotective phenotype after retinal ischemia/reperfusion injury19
Rutin pretreatment promotes microglial M1 to M2 phenotype polarization18
Vicious cycle of lipid peroxidation and iron accumulation in neurodegeneration18
Altered microRNA expression in animal models of Huntington’s disease and potential therapeutic strategies18
Stress increases MHC-I expression in dopaminergic neurons and induces autoimmune activation in Parkinson's disease18
Acupuncture enhances brain function in patients with mild cognitive impairment: evidence from a functional-near infrared spectroscopy study18
DL-3-n-butylphthalide alleviates motor disturbance by suppressing ferroptosis in a rat model of Parkinson’s disease18
Exosomes derived from human induced pluripotent stem cell-derived neural progenitor cells protect neuronal function under ischemic conditions18
Topical delivery of nerve growth factor for treatment of ocular and brain disorders18
Cathepsins in neuronal plasticity18
Bone marrow mesenchymal stem cells and exercise restore motor function following spinal cord injury by activating PI3K/AKT/mTOR pathway18
Pentadecapeptide BPC 157 and the central nervous system18
Advantages of Rho-associated kinases and their inhibitor fasudil for the treatment of neurodegenerative diseases18
One ring is sufficient to inhibit α-synuclein aggregation17
Nerve bundle formation during the promotion of peripheral nerve regeneration: collagen VI-neural cell adhesion molecule 1 interaction17
Therapeutic potential of dental pulp stem cell transplantation in a rat model of Alzheimer’s disease17
The role of peptidase neurolysin in neuroprotection and neural repair after stroke17
MicroRNA and mRNA profiling of cerebral cortex in a transgenic mouse model of Alzheimer’s disease by RNA sequencing17
Alterations in gut microbiota are related to metabolite profiles in spinal cord injury17
Islet amyloid polypeptide & amyloid beta peptide roles in Alzheimer’s disease: two triggers, one disease17
Stellate ganglion block reduces inflammation and improves neurological function in diabetic rats during ischemic stroke17
Presenilin mutations and their impact on neuronal differentiation in Alzheimer’s disease17
From cradle to grave: neurogenesis, neuroregeneration and neurodegeneration in Alzheimer’s and Parkinson’s diseases17
Efficacy of Lycium barbarum polysaccharide in adolescents with subthreshold depression: interim analysis of a randomized controlled study17
The mechanisms through which auricular vagus nerve stimulation protects against cerebral ischemia/reperfusion injury17
The plasminogen activating system in the pathogenesis of Alzheimer’s disease17
Dental pulp stem cells stimulate neuronal differentiation of PC12 cells17
Evaluation of the combined activity of benzimidazole arylhydrazones as new anti-Parkinsonian agents: monoamine oxidase-B inhibition, neuroprotection and oxidative stress modulation17
miR-103-3p targets Ndel1 to regulate neural stem cell proliferation and differentiation16
Hippo signaling: bridging the gap between cancer and neurodegenerative disorders16
Solid lipid nanoparticles loading with curcumin and dexanabinol to treat major depressive disorder16
Pannexin 1, a large-pore membrane channel, contributes to hypotonicity-induced ATP release in Schwann cells16
Delayed atomoxetine or fluoxetine treatment coupled with limited voluntary running promotes motor recovery in mice after ischemic stroke16
Current application of neurofilaments in amyotrophic lateral sclerosis and future perspectives16
Exogenous platelet-derived growth factor improves neurovascular unit recovery after spinal cord injury16
TLR2 and TLR4-mediated inflammation in Alzheimer’s disease: self-defense or sabotage?16
Microglial activation and adult neurogenesis after brain stroke16
Diabetic retinopathy: neurovascular disease requiring neuroprotective and regenerative therapies16
SOCS1/JAK2/STAT3 axis regulates early brain injury induced by subarachnoid hemorrhage via inflammatory responses16
Lithium promotes recovery after spinal cord injury16
Neuron-fibrous scaffold interfaces in the peripheral nervous system: a perspective on the structural requirements16
Inhibition of microRNA-29b suppresses oxidative stress and reduces apoptosis in ischemic stroke16
MicroRNAs as biomarkers in glaucoma and potential therapeutic targets16
Axonal remodeling of the corticospinal tract during neurological recovery after stroke16
Promoting axon regeneration in the central nervous system by increasing PI3-kinase signaling16
M1-type microglia can induce astrocytes to deposit chondroitin sulfate proteoglycan after spinal cord injury16
Aquaporin 4 deficiency eliminates the beneficial effects of voluntary exercise in a mouse model of Alzheimer’s disease16
Argon reduces microglial activation and inflammatory cytokine expression in retinal ischemia/reperfusion injury16
Oligodendrocyte precursor cell maturation: role of adenosine receptors15
P2X4 receptor participates in autophagy regulation in Parkinson's disease15
Icariin ameliorates memory deficits through regulating brain insulin signaling and glucose transporters in 3×Tg-AD mice15
Promise of metformin for preventing age-related cognitive dysfunction15
Functional repertoire of protein kinases and phosphatases in synaptic plasticity and associated neurological disorders15
Angiogenesis and nerve regeneration induced by local administration of plasmid pBud-coVEGF165-coFGF2 into the intact rat sciatic nerve15
Dynamic changes in the systemic immune responses of spinal cord injury model mice15
Brain delivering RNA-based therapeutic strategies by targeting mTOR pathway for axon regeneration after central nervous system injury15
Construction and imaging of a neurovascular unit model15
Melatonin, circadian rhythms and glaucoma: current perspective15
Mens sana in corpore sano: lifestyle changes modify astrocytes to contain Alzheimer’s disease15
Olfactory ensheathing cell transplantation alters the expression of chondroitin sulfate proteoglycans and promotes axonal regeneration after spinal cord injury15
Neural stem cell transplantation alleviates functional cognitive deficits in a mouse model of tauopathy15
MicroRNAs as diagnostic and prognostic biomarkers of age-related macular degeneration: advances and limitations15
Vimentin as a potential target for diverse nervous system diseases15
Mechanisms implicated in the contralateral effect in the central nervous system after unilateral injury: focus on the visual system15
Reduced graphene oxide-embedded nerve conduits loaded with bone marrow mesenchymal stem cell-derived extracellular vesicles promote peripheral nerve regeneration15
Advance in the use of gold nanoparticles in the treatment of neurodegenerative diseases: new perspectives15
From regenerative strategies to pharmacological approaches: can we fine-tune treatment for Parkinson’s disease?15
Inflammation and retinal degenerative diseases15
Transcranial magnetic stimulation in animal models of neurodegeneration15
Ascorbic acid accelerates Wallerian degeneration after peripheral nerve injury15
Non-coding RNAs and other determinants of neuroinflammation and endothelial dysfunction: regulation of gene expression in the acute phase of ischemic stroke and possible therapeutic applications14
Cerebellar pathology in motor neuron disease: neuroplasticity and neurodegeneration14
Role of microtubule dynamics in Wallerian degeneration and nerve regeneration after peripheral nerve injury14
Brain ischemia as a bridge to Alzheimer’s disease14
Role of circular RNA expression in the pathological progression after spinal cord injury14
Oxidative stress battles neuronal Bcl-xL in a fight to the death14
Challenges in developing therapeutic strategies for mild neonatal encephalopathy14
The Alzheimer’s disease-associated gene TREML2 modulates inflammation by regulating microglia polarization and NLRP3 inflammasome activation14
Production of chitosan scaffolds by lyophilization or electrospinning: which is better for peripheral nerve regeneration?14
A hyaluronic acid granular hydrogel nerve guidance conduit promotes regeneration and functional recovery of injured sciatic nerves in rats14
Spastin interacts with collapsin response mediator protein 3 to regulate neurite growth and branching14
The gut microbiome: implications for neurogenesis and neurological diseases14
Regulated upon activation, normal T cell expressed and secreted (RANTES) levels in the peripheral blood of patients with Alzheimer’s disease14
Brain-derived neurotrophic factor protects against acrylamide-induced neuronal and synaptic injury via the TrkB-MAPK-Erk1/2 pathway14
Neuroimmune connections between corticotropin-releasing hormone and mast cells: novel strategies for the treatment of neurodegenerative diseases14
Ruxolitinib attenuates secondary injury after traumatic spinal cord injury14
Alzheimer’s disease: a tale of two diseases?14
Melatonin ameliorates microvessel abnormalities in the cerebral cortex and hippocampus in a rat model of Alzheimer’s disease14
CircLphn3 protects the blood-brain barrier in traumatic brain injury14
Elevated intraspinal pressure in traumatic spinal cord injury is a promising therapeutic target13
Apolipoprotein A1, the neglected relative of Apolipoprotein E and its potential role in Alzheimer’s disease13
Melatonin, tunneling nanotubes, mesenchymal cells, and tissue regeneration13
Mitochondrial inorganic polyphosphate (polyP): the missing link of mammalian bioenergetics13
Astaxanthin alleviates pathological brain aging through the upregulation of hippocampal synaptic proteins13
Significance of mitochondrial activity in neurogenesis and neurodegenerative diseases13
Oligodendrocyte pathology in fetal alcohol spectrum disorders13
Deletion of Krüppel-like factor-4 promotes axonal regeneration in mammals13
Emerging roles of GPR109A in regulation of neuroinflammation in neurological diseases and pain13
What do we know about the role of lncRNAs in multiple sclerosis?13
Bioinformatics analysis of ferroptosis in spinal cord injury13
The role of NLRP3 inflammasome for microglial response to peripheral inflammation13
Dying by fire: noncanonical functions of autophagy proteins in neuroinflammation and neurodegeneration13
The neurosphere assay: an effective in vitro technique to study neural stem cells13
HOTTIP downregulation reduces neuronal damage and microglial activation in Parkinson's disease cell and mouse models13
Anxiety, depression, and quality of life in Parkinson’s disease: the implications of multidisciplinary treatment13
Probiotics, prebiotics and their role in Alzheimer’s disease13
Neuroprotective and anti-inflammatory effects of a therapy combining agonists of nicotinic α7 and σ1 receptors in a rat model of Parkinson's disease13
Transcriptomic analysis reveals essential microRNAs after peripheral nerve injury13
Hippocampal insulin resistance and the Sirtuin 1 signaling pathway in diabetes-induced cognitive dysfunction13
Brain plasticity after peripheral nerve injury treatment with massage therapy based on resting-state functional magnetic resonance imaging13
Preventive electroacupuncture reduces cognitive deficits in a rat model of D-galactose-induced aging13
Exploring magneto-electric nanoparticles (MENPs): a platform for implanted deep brain stimulation13
Laminin-coated multifilament entubulation, combined with Schwann cells and glial cell line-derived neurotrophic factor, promotes unidirectional axonal regeneration in a rat model of thoracic spinal co13
Leukocyte telomere length and plasma interleukin-1β and interleukin-18 levels in mild cognitive impairment and Alzheimer’s disease: new biomarkers for diagnosis and disease progression?12
Transcranial focused ultrasound stimulation reduces vasogenic edema after middle cerebral artery occlusion in mice12
Long non-coding RNA MEG3 regulates autophagy after cerebral ischemia/reperfusion injury12
Gene-modified leucoconcentrate for personalized ex vivo gene therapy in a mini pig model of moderate spinal cord injury12
The neuroprotective effects of oxygen therapy in Alzheimer’s disease: a narrative review12
Combination of epidural electrical stimulation with ex vivo triple gene therapy for spinal cord injury: a proof of principle study12
Downregulation of miR-491-5p promotes neovascularization after traumatic brain injury12
Roles of the ocular pressure, pressure-sensitive ion channel, and elasticity in pressure-induced retinal diseases12
Neuroglobin and neuroprotection: the role of natural and synthetic compounds in neuroglobin pharmacological induction12
Molecular mechanisms underlying the neuroprotection of environmental enrichment in Parkinson’s disease12