Neural Regeneration Research

Article	Citations
Isoform- and cell-state-specific APOE homeostasis and function	825045808
Microglia regulation of synaptic plasticity and learning and memory	148
Pathological mechanisms and therapeutic strategies for Alzheimer’s disease	139
Amyloid-beta peptide and tau protein crosstalk in Alzheimer’s disease	83
Oxidative stress factors in Parkinson’s disease	80
Liproxstatin-1 is an effective inhibitor of oligodendrocyte ferroptosis induced by inhibition of glutathione peroxidase 4	77
Promising drug targets and associated therapeutic interventions in Parkinson’s disease	72
Astrocytes: a double-edged sword in neurodegenerative diseases	71
Research trends, hot spots and prospects for necroptosis in the field of neuroscience	66
Microglia-associated neuroinflammation is a potential therapeutic target for ischemic stroke	65
Do pyroptosis, apoptosis, and necroptosis (PANoptosis) exist in cerebral ischemia? Evidence from cell and rodent studies	60
Microglia in neurodegenerative diseases	56
Exosomes derived from bone marrow mesenchymal stem cells protect the injured spinal cord by inhibiting pericyte pyroptosis	49
The emerging role of probiotics in neurodegenerative diseases: new hope for Parkinson’s disease?	48
Apelin-13 inhibits apoptosis and excessive autophagy in cerebral ischemia/reperfusion injury	46
Targeting the core of neurodegeneration: FoxO, mTOR, and SIRT1	45
Mesenchymal stem cell treatment for peripheral nerve injury: a narrative review	45
Potential effects of mesenchymal stem cell derived extracellular vesicles and exosomal miRNAs in neurological disorders	39
Association between inflammatory bowel diseases and Parkinson’s disease: systematic review and meta-analysis	39
Targeting neuroinflammation in Alzheimer’s disease: from mechanisms to clinical applications	39
Lineage tracing of direct astrocyte-to-neuron conversion in the mouse cortex	39
Mitochondrial dysfunctions in neurodegenerative diseases: role in disease pathogenesis, strategies for analysis and therapeutic prospects	38
Mechanisms of neuroplasticity and brain degeneration: strategies for protection during the aging process	38
A multi-channel collagen scaffold loaded with neural stem cells for the repair of spinal cord injury	36
Inflammation induces zebrafish regeneration	36

Mechanism underlying treatment of ischemic stroke using acupuncture: transmission and regulation	34
Cortical plasticity and nerve regeneration after peripheral nerve injury	34
Inflammation in diabetic retinopathy: possible roles in pathogenesis and potential implications for therapy	34
Basic mechanisms of peripheral nerve injury and treatment via electrical stimulation	33
The NLRP3 inflammasome: a potential therapeutic target for traumatic brain injury	33
Ferroptosis: a critical player and potential therapeutic target in traumatic brain injury and spinal cord injury	32
Oral frailty and neurodegeneration in Alzheimer’s disease	32
Prospects for intelligent rehabilitation techniques to treat motor dysfunction	31
Role of exosomes in the pathogenesis of inflammation in Parkinson’s disease	30
The future of retinal gene therapy: evolving from subretinal to intravitreal vector delivery	30
Electroacupuncture improves learning and memory functions in a rat cerebral ischemia/reperfusion injury model through PI3K/Akt signaling pathway activation	30
SARS-CoV-2 involvement in central nervous system tissue damage	30
Interaction between Schwann cells and other cells during repair of peripheral nerve injury	30
Progress in clinical trials of cell transplantation for the treatment of spinal cord injury: how many questions remain unanswered?	29
Regulation of neuroimmune processes by damage- and resolution-associated molecular patterns	29
The Yin-Yang of osteopontin in nervous system diseases: damage versus repair	28
TP53-induced glycolysis and apoptosis regulator alleviates hypoxia/ischemia-induced microglial pyroptosis and ischemic brain damage	28
The interaction of stem cells and vascularity in peripheral nerve regeneration	28
Abnormal characterization of dynamic functional connectivity in Alzheimer’s disease	28
Quercetin protects against diabetic retinopathy in rats by inducing heme oxygenase-1 expression	27
Therapeutic potential of trehalose in neurodegenerative diseases: the knowns and unknowns	27
Liposome based drug delivery as a potential treatment option for Alzheimer’s disease	27
Microglia activation, classification and microglia-mediated neuroinflammatory modulators in subarachnoid hemorrhage	27
Delving into the recent advancements of spinal cord injury treatment: a review of recent progress	27
P2X7 receptor activation aggravates NADPH oxidase 2-induced oxidative stress after intracerebral hemorrhage	26
Epidural electrical stimulation for spinal cord injury	26
Physiopathology of ischemic stroke and its modulation using memantine: evidence from preclinical stroke	26
Regulation of neuronal bioenergetics as a therapeutic strategy in neurodegenerative diseases	26
Urolithin A alleviates blood-brain barrier disruption and attenuates neuronal apoptosis following traumatic brain injury in mice	26
PANoptosis-like cell death in ischemia/reperfusion injury of retinal neurons	26
Potential therapeutic effects of polyphenols in Parkinson's disease: in vivo and in vitro pre-clinical studies	25
Deciphering the role of PGC-1α in neurological disorders: from mitochondrial dysfunction to synaptic failure	25
Low-dose lipopolysaccharide as an immune regulator for homeostasis maintenance in the central nervous system through transformation to neuroprotective microglia	25
LncRNA Airsci increases the inflammatory response after spinal cord injury in rats through the nuclear factor kappa B signaling pathway	25
Insights into stem cell therapy for diabetic retinopathy: a bibliometric and visual analysis	25
Motor tract reorganization after acute central nervous system injury: a translational perspective	25
Progress in clinical trials of stem cell therapy for cerebral palsy	25
Pro- and anti-epileptic roles of microglia	25
Application of modern neuroimaging technology in the diagnosis and study of Alzheimer's disease	25
Chronic peripheral inflammation: a possible contributor to neurodegenerative diseases	25
Graphene oxide-composited chitosan scaffold contributes to functional recovery of injured spinal cord in rats	24
The relationship between amyloid-beta and brain capillary endothelial cells in Alzheimer’s disease	24
Parkinson’s disease and diabetes mellitus: common mechanisms and treatment repurposing	24
Survivors of COVID-19 exhibit altered amplitudes of low frequency fluctuation in the brain: a resting-state functional magnetic resonance imaging study at 1-year follow-up	24
Neural stem cell-derived exosome as a nano-sized carrier for BDNF delivery to a rat model of ischemic stroke	24
Potential neuroprotection by Dendrobium nobile Lindl alkaloid in Alzheimer’s disease models	24
The secretome of endothelial progenitor cells: a potential therapeutic strategy for ischemic stroke	24
Hyperglycemia in acute ischemic stroke: physiopathological and therapeutic complexity	23
Neuroregeneration and functional recovery after stroke: advancing neural stem cell therapy toward clinical application	23
Role of vitamin B12 deficiency in ischemic stroke risk and outcome	23

Astrocytes protect dopaminergic neurons against aminochrome neurotoxicity	23
Phytochemicals as inhibitors of tumor necrosis factor alpha and neuroinflammatory responses in neurodegenerative diseases	23
Initial failures of anti-tau antibodies in Alzheimer’s disease are reminiscent of the amyloid-β story	23
Efficacy and safety of transcutaneous auricular vagus nerve stimulation combined with conventional rehabilitation training in acute stroke patients: a randomized controlled trial conducted for 1 year	22
Retinal regeneration requires dynamic Notch signaling	22
Current application and future directions of photobiomodulation in central nervous diseases	22
Spinal cord injury-induced cognitive impairment: a narrative review	22
Enriched environment boosts the post-stroke recovery of neurological function by promoting autophagy	22
Neutrophil-to-lymphocyte ratio in sporadic amyotrophic lateral sclerosis	22
Emerging blood exosome-based biomarkers for preclinical and clinical Alzheimer’s disease: a meta-analysis and systematic review	22
Axonal regeneration and sprouting as a potential therapeutic target for nervous system disorders	22
Lithium beyond psychiatric indications: the reincarnation of a new old drug	21
Application of neurotrophic and proangiogenic factors as therapy after peripheral nervous system injury	21
GDNF to the rescue: GDNF delivery effects on motor neurons and nerves, and muscle re-innervation after peripheral nerve injuries	21
Diabetes mellitus and Parkinson’s disease: dangerous liaisons between insulin and dopamine	21
Maraviroc promotes recovery from traumatic brain injury in mice by suppression of neuroinflammation and activation of neurotoxic reactive astrocytes	21
Cognitive impairment in multiple sclerosis: lessons from cerebrospinal fluid biomarkers	21
Rapid GFAP and Iba1 expression changes in the female rat brain following spinal cord injury	21
Glucagon-like peptide-1/glucose-dependent insulinotropic polypeptide dual receptor agonist DA-CH5 is superior to exendin-4 in protecting neurons in the 6-hydroxydopamine rat Parkinson model	21
Repetitive transcranial magnetic stimulation for lower extremity motor function in patients with stroke: a systematic review and network meta-analysis	21
Baicalin attenuates blood-spinal cord barrier disruption and apoptosis through PI3K/Akt signaling pathway after spinal cord injury	21
Collagen/heparan sulfate porous scaffolds loaded with neural stem cells improve neurological function in a rat model of traumatic brain injury	20
Exosomes derived from bone marrow mesenchymal stem cells inhibit neuroinflammation after traumatic brain injury	20
Neuroinflammation as a mechanism linking hypertension with the increased risk of Alzheimer’s disease	20
Degenerative and regenerative processes in amyotrophic lateral sclerosis: motor reserve, adaptation and putative compensatory changes	20
Role of apoptosis-inducing factor in perinatal hypoxic-ischemic brain injury	20
Exosomal miR-23b from bone marrow mesenchymal stem cells alleviates oxidative stress and pyroptosis after intracerebral hemorrhage	20
Analysis of corneal nerve plexus in corneal confocal microscopy images	20
Hydrogel-based local drug delivery strategies for spinal cord repair	20
Repurposed anti-cancer epidermal growth factor receptor inhibitors: mechanisms of neuroprotective effects in Alzheimer’s disease	20
Brain-derived neurotrophic factor and its related enzymes and receptors play important roles after hypoxic-ischemic brain damage	20
Ultrasonic vocalizations in mice: relevance for ethologic and neurodevelopmental disorders studies	20
Corneal neuromediator profiles following laser refractive surgery	20
Circulating extracellular vesicles: friends and foes in neurodegeneration	20
Diabetic corneal neuropathy as a surrogate marker for diabetic peripheral neuropathy	20
Neuronal reprogramming in treating spinal cord injury	19
Toward three-dimensional in vitro models to study neurovascular unit functions in health and disease	19
Lycium barbarum polysaccharide-glycoprotein preventative treatment ameliorates aversive	19
Inhibition of LncRNA Vof-16 expression promotes nerve regeneration and functional recovery after spinal cord injury	19
Microglial depletion impairs glial scar formation and aggravates inflammation partly by inhibiting STAT3 phosphorylation in astrocytes after spinal cord injury	19
Interleukin-4 promotes microglial polarization toward a neuroprotective phenotype after retinal ischemia/reperfusion injury	19
Neuroprotective effects of naturally sourced bioactive polysaccharides: an update	19
Down-regulating Circular RNA Prkcsh suppresses the inflammatory response after spinal cord injury	19
Adipose tissue, systematic inflammation, and neurodegenerative diseases	19
Temporal changes in inflammatory mitochondria-enriched microRNAs following traumatic brain injury and effects of miR-146a nanoparticle delivery	19
Topical delivery of nerve growth factor for treatment of ocular and brain disorders	18
Stress increases MHC-I expression in dopaminergic neurons and induces autoimmune activation in Parkinson's disease	18
Acupuncture enhances brain function in patients with mild cognitive impairment: evidence from a functional-near infrared spectroscopy study	18
Exploration of the mechanism by which icariin modulates hippocampal neurogenesis in a rat model of depression	18
The influence of gut microbiota alteration on age-related neuroinflammation and cognitive decline	18
The use of hydrogel-delivered extracellular vesicles in recovery of motor function in stroke: a testable experimental hypothesis for clinical translation including behavioral and neuroimaging assessme	18
Phosphorylated tau as a toxic agent in synaptic mitochondria: implications in aging and Alzheimer’s disease	18
Hypoxia in Alzheimer's disease: effects of hypoxia inducible factors	18
Cathepsins in neuronal plasticity	18
Neuroimaging mechanisms of high-frequency repetitive transcranial magnetic stimulation for treatment of amnestic mild cognitive impairment: a double-blind randomized sham-controlled trial	18
Exosomes derived from human induced pluripotent stem cell-derived neural progenitor cells protect neuronal function under ischemic conditions	18
Connexin therapeutics: blocking connexin hemichannel pores is distinct from blocking pannexin channels or gap junctions	18
Advantages of Rho-associated kinases and their inhibitor fasudil for the treatment of neurodegenerative diseases	18
VX-765 reduces neuroinflammation after spinal cord injury in mice	18
Rutin pretreatment promotes microglial M1 to M2 phenotype polarization	18
The “mitochondrial stress responses”: the “Dr. Jekyll and Mr. Hyde” of neuronal disorders	18
The mechanisms through which auricular vagus nerve stimulation protects against cerebral ischemia/reperfusion injury	17
Presenilin mutations and their impact on neuronal differentiation in Alzheimer’s disease	17
Dental pulp stem cells stimulate neuronal differentiation of PC12 cells	17
Pentadecapeptide BPC 157 and the central nervous system	17
One ring is sufficient to inhibit α-synuclein aggregation	17
Stellate ganglion block reduces inflammation and improves neurological function in diabetic rats during ischemic stroke	17
Therapeutic potential of dental pulp stem cell transplantation in a rat model of Alzheimer’s disease	17
Evaluation of the combined activity of benzimidazole arylhydrazones as new anti-Parkinsonian agents: monoamine oxidase-B inhibition, neuroprotection and oxidative stress modulation	17
Altered microRNA expression in animal models of Huntington’s disease and potential therapeutic strategies	17
Islet amyloid polypeptide & amyloid beta peptide roles in Alzheimer’s disease: two triggers, one disease	17
Nerve bundle formation during the promotion of peripheral nerve regeneration: collagen VI-neural cell adhesion molecule 1 interaction	17
The plasminogen activating system in the pathogenesis of Alzheimer’s disease	17
From cradle to grave: neurogenesis, neuroregeneration and neurodegeneration in Alzheimer’s and Parkinson’s diseases	17
MicroRNA and mRNA profiling of cerebral cortex in a transgenic mouse model of Alzheimer’s disease by RNA sequencing	17
Neuron-fibrous scaffold interfaces in the peripheral nervous system: a perspective on the structural requirements	16
Exogenous platelet-derived growth factor improves neurovascular unit recovery after spinal cord injury	16
TLR2 and TLR4-mediated inflammation in Alzheimer’s disease: self-defense or sabotage?	16
Axonal remodeling of the corticospinal tract during neurological recovery after stroke	16
Microglial activation and adult neurogenesis after brain stroke	16

DL-3-n-butylphthalide alleviates motor disturbance by suppressing ferroptosis in a rat model of Parkinson’s disease	16
M1-type microglia can induce astrocytes to deposit chondroitin sulfate proteoglycan after spinal cord injury	16
The role of peptidase neurolysin in neuroprotection and neural repair after stroke	16
miR-103-3p targets Ndel1 to regulate neural stem cell proliferation and differentiation	16
Alterations in gut microbiota are related to metabolite profiles in spinal cord injury	16
Pannexin 1, a large-pore membrane channel, contributes to hypotonicity-induced ATP release in Schwann cells	16
Bone marrow mesenchymal stem cells and exercise restore motor function following spinal cord injury by activating PI3K/AKT/mTOR pathway	16
Current application of neurofilaments in amyotrophic lateral sclerosis and future perspectives	16
Argon reduces microglial activation and inflammatory cytokine expression in retinal ischemia/reperfusion injury	16
MicroRNAs as biomarkers in glaucoma and potential therapeutic targets	16
Solid lipid nanoparticles loading with curcumin and dexanabinol to treat major depressive disorder	16
Efficacy of Lycium barbarum polysaccharide in adolescents with subthreshold depression: interim analysis of a randomized controlled study	16
Diabetic retinopathy: neurovascular disease requiring neuroprotective and regenerative therapies	16
Delayed atomoxetine or fluoxetine treatment coupled with limited voluntary running promotes motor recovery in mice after ischemic stroke	16
Oligodendrocyte precursor cell maturation: role of adenosine receptors	15
Promoting axon regeneration in the central nervous system by increasing PI3-kinase signaling	15
From regenerative strategies to pharmacological approaches: can we fine-tune treatment for Parkinson’s disease?	15
Neural stem cell transplantation alleviates functional cognitive deficits in a mouse model of tauopathy	15
Hippo signaling: bridging the gap between cancer and neurodegenerative disorders	15
Ascorbic acid accelerates Wallerian degeneration after peripheral nerve injury	15
Reduced graphene oxide-embedded nerve conduits loaded with bone marrow mesenchymal stem cell-derived extracellular vesicles promote peripheral nerve regeneration	15
Melatonin, circadian rhythms and glaucoma: current perspective	15
SOCS1/JAK2/STAT3 axis regulates early brain injury induced by subarachnoid hemorrhage via inflammatory responses	15
Functional repertoire of protein kinases and phosphatases in synaptic plasticity and associated neurological disorders	15
Transcranial magnetic stimulation in animal models of neurodegeneration	15
Inhibition of microRNA-29b suppresses oxidative stress and reduces apoptosis in ischemic stroke	15
Brain delivering RNA-based therapeutic strategies by targeting mTOR pathway for axon regeneration after central nervous system injury	15
Mechanisms implicated in the contralateral effect in the central nervous system after unilateral injury: focus on the visual system	15
Mens sana in corpore sano: lifestyle changes modify astrocytes to contain Alzheimer’s disease	15
Promise of metformin for preventing age-related cognitive dysfunction	15
Inflammation and retinal degenerative diseases	15
Lithium promotes recovery after spinal cord injury	15
Vimentin as a potential target for diverse nervous system diseases	15
Angiogenesis and nerve regeneration induced by local administration of plasmid pBud-coVEGF165-coFGF2 into the intact rat sciatic nerve	15
The gut microbiome: implications for neurogenesis and neurological diseases	14
Construction and imaging of a neurovascular unit model	14
The Alzheimer’s disease-associated gene TREML2 modulates inflammation by regulating microglia polarization and NLRP3 inflammasome activation	14
Vicious cycle of lipid peroxidation and iron accumulation in neurodegeneration	14
A hyaluronic acid granular hydrogel nerve guidance conduit promotes regeneration and functional recovery of injured sciatic nerves in rats	14
MicroRNAs as diagnostic and prognostic biomarkers of age-related macular degeneration: advances and limitations	14
CircLphn3 protects the blood-brain barrier in traumatic brain injury	14
Oxidative stress battles neuronal Bcl-xL in a fight to the death	14
Cerebellar pathology in motor neuron disease: neuroplasticity and neurodegeneration	14
Olfactory ensheathing cell transplantation alters the expression of chondroitin sulfate proteoglycans and promotes axonal regeneration after spinal cord injury	14
Aquaporin 4 deficiency eliminates the beneficial effects of voluntary exercise in a mouse model of Alzheimer’s disease	14
Brain ischemia as a bridge to Alzheimer’s disease	14
Alzheimer’s disease: a tale of two diseases?	14
Spastin interacts with collapsin response mediator protein 3 to regulate neurite growth and branching	14
Challenges in developing therapeutic strategies for mild neonatal encephalopathy	14
P2X4 receptor participates in autophagy regulation in Parkinson's disease	14
Advance in the use of gold nanoparticles in the treatment of neurodegenerative diseases: new perspectives	14
Role of microtubule dynamics in Wallerian degeneration and nerve regeneration after peripheral nerve injury	14
Role of circular RNA expression in the pathological progression after spinal cord injury	14
Dynamic changes in the systemic immune responses of spinal cord injury model mice	14
Significance of mitochondrial activity in neurogenesis and neurodegenerative diseases	13
Neuroimmune connections between corticotropin-releasing hormone and mast cells: novel strategies for the treatment of neurodegenerative diseases	13
Ruxolitinib attenuates secondary injury after traumatic spinal cord injury	13
What do we know about the role of lncRNAs in multiple sclerosis?	13
Mitochondrial inorganic polyphosphate (polyP): the missing link of mammalian bioenergetics	13
Non-coding RNAs and other determinants of neuroinflammation and endothelial dysfunction: regulation of gene expression in the acute phase of ischemic stroke and possible therapeutic applications	13
Brain-derived neurotrophic factor protects against acrylamide-induced neuronal and synaptic injury via the TrkB-MAPK-Erk1/2 pathway	13
HOTTIP downregulation reduces neuronal damage and microglial activation in Parkinson's disease cell and mouse models	13
Laminin-coated multifilament entubulation, combined with Schwann cells and glial cell line-derived neurotrophic factor, promotes unidirectional axonal regeneration in a rat model of thoracic spinal co	13
Emerging roles of GPR109A in regulation of neuroinflammation in neurological diseases and pain	13
Neuroprotective and anti-inflammatory effects of a therapy combining agonists of nicotinic α7 and σ1 receptors in a rat model of Parkinson's disease	13
Production of chitosan scaffolds by lyophilization or electrospinning: which is better for peripheral nerve regeneration?	13
Hippocampal insulin resistance and the Sirtuin 1 signaling pathway in diabetes-induced cognitive dysfunction	13
The role of NLRP3 inflammasome for microglial response to peripheral inflammation	13
Dying by fire: noncanonical functions of autophagy proteins in neuroinflammation and neurodegeneration	13
Icariin ameliorates memory deficits through regulating brain insulin signaling and glucose transporters in 3×Tg-AD mice	13
Anxiety, depression, and quality of life in Parkinson’s disease: the implications of multidisciplinary treatment	13
Oligodendrocyte pathology in fetal alcohol spectrum disorders	13
Elevated intraspinal pressure in traumatic spinal cord injury is a promising therapeutic target	13
Deletion of Krüppel-like factor-4 promotes axonal regeneration in mammals	13
Transcriptomic analysis reveals essential microRNAs after peripheral nerve injury	13
Melatonin ameliorates microvessel abnormalities in the cerebral cortex and hippocampus in a rat model of Alzheimer’s disease	13
Astaxanthin alleviates pathological brain aging through the upregulation of hippocampal synaptic proteins	13
Exploring magneto-electric nanoparticles (MENPs): a platform for implanted deep brain stimulation	13
Preventive electroacupuncture reduces cognitive deficits in a rat model of D-galactose-induced aging	13
Rethinking the necessity of low glucose intervention for cerebral ischemia/reperfusion injury	12
Characteristics of neural growth and cryopreservation of the dorsal root ganglion using three-dimensional collagen hydrogel culture versus conventional culture	12
Hydrogen sulfide enhances adult neurogenesis in a mouse model of Parkinson’s disease	12
Roles of the ocular pressure, pressure-sensitive ion channel, and elasticity in pressure-induced retinal diseases	12
Gene-modified leucoconcentrate for personalized ex vivo gene therapy in a mini pig model of moderate spinal cord injury	12
The mechanism behind activation of the Nod-like receptor family protein 3 inflammasome in Parkinson’s disease	12
Astrocyte polarization in glaucoma: a new opportunity	12
Apolipoprotein A1, the neglected relative of Apolipoprotein E and its potential role in Alzheimer’s disease	12
Combination of epidural electrical stimulation with ex vivo triple gene therapy for spinal cord injury: a proof of principle study	12
Melatonin, tunneling nanotubes, mesenchymal cells, and tissue regeneration	12
Arbutin effectively ameliorates the symptoms of Parkinson’s disease: the role of adenosine receptors and cyclic adenosine monophosphate	12
Co-nanoencapsulated meloxicam and curcumin improves cognitive impairment induced by amyloid-beta through modulation of cyclooxygenase-2 in mice	12
All roads lead to Rome — a review of the potential mechanisms by which exerkines exhibit neuroprotective effects in Alzheimer’s disease	12
Transcranial focused ultrasound stimulation reduces vasogenic edema after middle cerebral artery occlusion in mice	12
Neuroglobin and neuroprotection: the role of natural and synthetic compounds in neuroglobin pharmacological induction	12
Molecular mechanisms underlying the neuroprotection of environmental enrichment in Parkinson’s disease	12