OOIR: Observatory of International Research

Papers

(The TQCC of Cellular & Molecular Immunology is 42. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-04-01 to 2024-04-01.)

Article	Citations
The history and advances in cancer immunotherapy: understanding the characteristics of tumor-infiltrating immune cells and their therapeutic implications	1126
Necroptosis, pyroptosis and apoptosis: an intricate game of cell death	731
NLRP3 inflammasome activation and cell death	483
Tumor-infiltrating lymphocytes in the immunotherapy era	396
Key residues of the receptor binding motif in the spike protein of SARS-CoV-2 that interact with ACE2 and neutralizing antibodies	390
The ORF3a protein of SARS-CoV-2 induces apoptosis in cells	373
Serum IgA, IgM, and IgG responses in COVID-19	362
Human monoclonal antibodies block the binding of SARS-CoV-2 spike protein to angiotensin converting enzyme 2 receptor	305
An update on the regulatory mechanisms of NLRP3 inflammasome activation	300
Hepatic macrophages in liver homeostasis and diseases-diversity, plasticity and therapeutic opportunities	291
SARS-CoV-2 Orf9b suppresses type I interferon responses by targeting TOM70	272
A longitudinal study of SARS-CoV-2-infected patients reveals a high correlation between neutralizing antibodies and COVID-19 severity	257
Neutrophil chemoattractant receptors in health and disease: double-edged swords	251
Elevated serum levels of S100A8/A9 and HMGB1 at hospital admission are correlated with inferior clinical outcomes in COVID-19 patients	194
Macrophages and the maintenance of homeostasis	184
Cancer immunotherapy with γδ T cells: many paths ahead of us	179
Antigen presentation by dendritic cells and their instruction of CD4+ T helper cell responses	178
Neutrophils in chronic inflammatory diseases	178
The blood–brain barrier in systemic infection and inflammation	177
Gut microbiota-derived metabolites in the regulation of host immune responses and immune-related inflammatory diseases	177
Regulation of RIG-I-like receptor-mediated signaling: interaction between host and viral factors	175
Gut microbiome, liver immunology, and liver diseases	174
Increased immune escape of the new SARS-CoV-2 variant of concern Omicron	166
Unique immunological profile in patients with COVID-19	161
Control of lymphocyte functions by gut microbiota-derived short-chain fatty acids	160

Linear epitopes of SARS-CoV-2 spike protein elicit neutralizing antibodies in COVID-19 patients	158
Immunobiology and immunotherapy of HCC: spotlight on innate and innate-like immune cells	154
Dendritic cell migration in inflammation and immunity	153
New insights into the evasion of host innate immunity by Mycobacterium tuberculosis	144
SARS-CoV-2 membrane glycoprotein M antagonizes the MAVS-mediated innate antiviral response	135
SARS-CoV-2-specific T cells in infection and vaccination	125
Metabolism of tissue macrophages in homeostasis and pathology	124
Allogeneic Vγ9Vδ2 T-cell immunotherapy exhibits promising clinical safety and prolongs the survival of patients with late-stage lung or liver cancer	115
Activation or exhaustion of CD8+ T cells in patients with COVID-19	107
Manganese salts function as potent adjuvants	106
Pathological and molecular examinations of postmortem testis biopsies reveal SARS-CoV-2 infection in the testis and spermatogenesis damage in COVID-19 patients	103
The cutting-edge progress of immune-checkpoint blockade in lung cancer	102
Ubiquitination of SARS-CoV-2 ORF7a promotes antagonism of interferon response	102
High-dimensional immune profiling by mass cytometry revealed immunosuppression and dysfunction of immunity in COVID-19 patients	102
Tumor-associated myeloid cells: diversity and therapeutic targeting	100
SARS-CoV-2 ORF10 suppresses the antiviral innate immune response by degrading MAVS through mitophagy	98
Immunological mechanisms and therapeutic targets of fatty liver diseases	97
Tertiary lymphoid structures in cancer – considerations for patient prognosis	94
SARS-CoV-2 nsp12 attenuates type I interferon production by inhibiting IRF3 nuclear translocation	93
Shared and distinct roles of T peripheral helper and T follicular helper cells in human diseases	91
Dendritic cells in cancer immunology	91
Phase I study of CAR-T cells with PD-1 and TCR disruption in mesothelin-positive solid tumors	90
Neutralizing antibodies for the prevention and treatment of COVID-19	90
ACOD1 in immunometabolism and disease	88
Human immunology and immunotherapy: main achievements and challenges	87
Phages and their potential to modulate the microbiome and immunity	83
Neutrophils in liver diseases: pathogenesis and therapeutic targets	83
Low serum neutralizing anti-SARS-CoV-2 S antibody levels in mildly affected COVID-19 convalescent patients revealed by two different detection methods	83
Emerging SARS-CoV-2 variants reduce neutralization sensitivity to convalescent sera and monoclonal antibodies	81
Signaling from T cell receptors (TCRs) and chimeric antigen receptors (CARs) on T cells	81
New insights into the cell- and tissue-specificity of glucocorticoid actions	81
Challenges and strategies for next-generation bispecific antibody-based antitumor therapeutics	79
Enhancing CAR-T cell efficacy in solid tumors by targeting the tumor microenvironment	74
Dendritic cell deficiencies persist seven months after SARS-CoV-2 infection	73
Pyroptotic macrophages stimulate the SARS-CoV-2-associated cytokine storm	73
Expansion of atypical memory B cells is a prominent feature of COVID-19	72
Ligand recognition by the γδ TCR and discrimination between homeostasis and stress conditions	71
USP19 suppresses inflammation and promotes M2-like macrophage polarization by manipulating NLRP3 function via autophagy	69
Immunopathobiology and therapeutic targets related to cytokines in liver diseases	69
T cell epitopes in SARS-CoV-2 proteins are substantially conserved in the Omicron variant	67
A compromised specific humoral immune response against the SARS-CoV-2 receptor-binding domain is related to viral persistence and periodic shedding in the gastrointestinal tract	66
NKG2A and COVID-19: another brick in the wall	64
T cell immune responses to SARS-CoV-2 and variants of concern (Alpha and Delta) in infected and vaccinated individuals	64
Autoimmmune hepatitis	64
RRx-001 ameliorates inflammatory diseases by acting as a potent covalent NLRP3 inhibitor	63
“Autoinflammatory psoriasis”—genetics and biology of pustular psoriasis	63
Therapeutic efficacy of anti-CD19 CAR-T cells in a mouse model of systemic lupus erythematosus	62
Microglia as hackers of the matrix: sculpting synapses and the extracellular space	62
Single-cell profiling reveals the trajectories of natural killer cell differentiation in bone marrow and a stress signature induced by acute myeloid leukemia	62
The aryl hydrocarbon receptor and the gut–brain axis	61

Impact of intracellular innate immune receptors on immunometabolism	61
The essential functions of mitochondrial dynamics in immune cells	60
Retraction Note to: SARS-CoV-2 infects T lymphocytes through its spike protein-mediated membrane fusion	60
Ferritin nanoparticle-based SARS-CoV-2 RBD vaccine induces a persistent antibody response and long-term memory in mice	60
IFNγ signaling integrity in colorectal cancer immunity and immunotherapy	57
Construction of a sustainable 3-hydroxybutyrate-producing probiotic Escherichia coli for treatment of colitis	56
The roles of microglia in viral encephalitis: from sensome to therapeutic targeting	56
Olfactory ecto-mesenchymal stem cell-derived exosomes ameliorate murine Sjögren’s syndrome by modulating the function of myeloid-derived suppressor cells	56
Protein N-myristoylation: functions and mechanisms in control of innate immunity	55
HLA class I loss in colorectal cancer: implications for immune escape and immunotherapy	54
The soluble glycoprotein NMB (GPNMB) produced by macrophages induces cancer stemness and metastasis via CD44 and IL-33	53
Dynamic immune profiling identifies the stronger graft-versus-leukemia (GVL) effects with haploidentical allografts compared to HLA-matched stem cell transplantation	52
Identification of druggable inhibitory immune checkpoints on Natural Killer cells in COVID-19	52
Regulation of natural killer cell activity by glucocorticoids, serotonin, dopamine, and epinephrine	52
Maternal and fetal T cells in term pregnancy and preterm labor	50
The use of supercytokines, immunocytokines, engager cytokines, and other synthetic cytokines in immunotherapy	50
Tissue-specific Tregs in cancer metastasis: opportunities for precision immunotherapy	48
Recombinant vaccine containing an RBD-Fc fusion induced protection against SARS-CoV-2 in nonhuman primates and mice	48
Clinical development of CAR T cell therapy in China: 2020 update	47
Oxidized mitochondrial DNA sensing by STING signaling promotes the antitumor effect of an irradiated immunogenic cancer cell vaccine	47
OTUD5 promotes innate antiviral and antitumor immunity through deubiquitinating and stabilizing STING	46
Biology and pathology of the uterine microenvironment and its natural killer cells	44
Potential contribution of increased soluble IL-2R to lymphopenia in COVID-19 patients	44
Dynamics of the SARS-CoV-2 antibody response up to 10 months after infection	44
Ectopic Tcf1 expression instills a stem-like program in exhausted CD8+ T cells to enhance viral and tumor immunity	44
Protective humoral immunity in SARS-CoV-2 infected pediatric patients	43
SARS-CoV-2 infection in K18-ACE2 transgenic mice replicates human pulmonary disease in COVID-19	42
Innate lymphocytes: pathogenesis and therapeutic targets of liver diseases and cancer	42
SARS-CoV-2-specific T cell immunity to structural proteins in inactivated COVID-19 vaccine recipients	42