Cellular & Molecular Immunology

(The median citation count of Cellular & Molecular Immunology is 17. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-06-01 to 2024-06-01.)
The history and advances in cancer immunotherapy: understanding the characteristics of tumor-infiltrating immune cells and their therapeutic implications1259
Necroptosis, pyroptosis and apoptosis: an intricate game of cell death821
NLRP3 inflammasome activation and cell death530
Tumor-infiltrating lymphocytes in the immunotherapy era432
The ORF3a protein of SARS-CoV-2 induces apoptosis in cells378
Hepatic macrophages in liver homeostasis and diseases-diversity, plasticity and therapeutic opportunities325
An update on the regulatory mechanisms of NLRP3 inflammasome activation322
SARS-CoV-2 Orf9b suppresses type I interferon responses by targeting TOM70278
A longitudinal study of SARS-CoV-2-infected patients reveals a high correlation between neutralizing antibodies and COVID-19 severity260
Macrophages and the maintenance of homeostasis208
Neutrophils in chronic inflammatory diseases201
Elevated serum levels of S100A8/A9 and HMGB1 at hospital admission are correlated with inferior clinical outcomes in COVID-19 patients196
Gut microbiota-derived metabolites in the regulation of host immune responses and immune-related inflammatory diseases195
The blood–brain barrier in systemic infection and inflammation194
Regulation of RIG-I-like receptor-mediated signaling: interaction between host and viral factors191
Gut microbiome, liver immunology, and liver diseases188
Cancer immunotherapy with γδ T cells: many paths ahead of us188
Dendritic cell migration in inflammation and immunity178
Unique immunological profile in patients with COVID-19173
Control of lymphocyte functions by gut microbiota-derived short-chain fatty acids173
Increased immune escape of the new SARS-CoV-2 variant of concern Omicron172
Immunobiology and immunotherapy of HCC: spotlight on innate and innate-like immune cells163
Linear epitopes of SARS-CoV-2 spike protein elicit neutralizing antibodies in COVID-19 patients159
New insights into the evasion of host innate immunity by Mycobacterium tuberculosis155
Metabolism of tissue macrophages in homeostasis and pathology142
SARS-CoV-2 membrane glycoprotein M antagonizes the MAVS-mediated innate antiviral response137
SARS-CoV-2-specific T cells in infection and vaccination131
Manganese salts function as potent adjuvants126
Allogeneic Vγ9Vδ2 T-cell immunotherapy exhibits promising clinical safety and prolongs the survival of patients with late-stage lung or liver cancer122
Activation or exhaustion of CD8+ T cells in patients with COVID-19116
The cutting-edge progress of immune-checkpoint blockade in lung cancer110
Tumor-associated myeloid cells: diversity and therapeutic targeting108
Pathological and molecular examinations of postmortem testis biopsies reveal SARS-CoV-2 infection in the testis and spermatogenesis damage in COVID-19 patients107
Phase I study of CAR-T cells with PD-1 and TCR disruption in mesothelin-positive solid tumors107
SARS-CoV-2 ORF10 suppresses the antiviral innate immune response by degrading MAVS through mitophagy106
Ubiquitination of SARS-CoV-2 ORF7a promotes antagonism of interferon response105
Immunological mechanisms and therapeutic targets of fatty liver diseases104
Dendritic cells in cancer immunology103
Shared and distinct roles of T peripheral helper and T follicular helper cells in human diseases102
SARS-CoV-2 nsp12 attenuates type I interferon production by inhibiting IRF3 nuclear translocation95
Human immunology and immunotherapy: main achievements and challenges94
ACOD1 in immunometabolism and disease94
Phages and their potential to modulate the microbiome and immunity92
Neutralizing antibodies for the prevention and treatment of COVID-1991
New insights into the cell- and tissue-specificity of glucocorticoid actions88
Neutrophils in liver diseases: pathogenesis and therapeutic targets85
Enhancing CAR-T cell efficacy in solid tumors by targeting the tumor microenvironment83
Emerging SARS-CoV-2 variants reduce neutralization sensitivity to convalescent sera and monoclonal antibodies83
Low serum neutralizing anti-SARS-CoV-2 S antibody levels in mildly affected COVID-19 convalescent patients revealed by two different detection methods83
Ligand recognition by the γδ TCR and discrimination between homeostasis and stress conditions77
Dendritic cell deficiencies persist seven months after SARS-CoV-2 infection77
T cell epitopes in SARS-CoV-2 proteins are substantially conserved in the Omicron variant76
USP19 suppresses inflammation and promotes M2-like macrophage polarization by manipulating NLRP3 function via autophagy75
Pyroptotic macrophages stimulate the SARS-CoV-2-associated cytokine storm75
Immunopathobiology and therapeutic targets related to cytokines in liver diseases75
Expansion of atypical memory B cells is a prominent feature of COVID-1972
Impact of intracellular innate immune receptors on immunometabolism70
RRx-001 ameliorates inflammatory diseases by acting as a potent covalent NLRP3 inhibitor69
Single-cell profiling reveals the trajectories of natural killer cell differentiation in bone marrow and a stress signature induced by acute myeloid leukemia69
Autoimmmune hepatitis69
A compromised specific humoral immune response against the SARS-CoV-2 receptor-binding domain is related to viral persistence and periodic shedding in the gastrointestinal tract68
“Autoinflammatory psoriasis”—genetics and biology of pustular psoriasis66
T cell immune responses to SARS-CoV-2 and variants of concern (Alpha and Delta) in infected and vaccinated individuals66
Microglia as hackers of the matrix: sculpting synapses and the extracellular space65
The essential functions of mitochondrial dynamics in immune cells64
Olfactory ecto-mesenchymal stem cell-derived exosomes ameliorate murine Sjögren’s syndrome by modulating the function of myeloid-derived suppressor cells64
Ferritin nanoparticle-based SARS-CoV-2 RBD vaccine induces a persistent antibody response and long-term memory in mice64
Retraction Note to: SARS-CoV-2 infects T lymphocytes through its spike protein-mediated membrane fusion62
The aryl hydrocarbon receptor and the gut–brain axis62
Construction of a sustainable 3-hydroxybutyrate-producing probiotic Escherichia coli for treatment of colitis61
HLA class I loss in colorectal cancer: implications for immune escape and immunotherapy60
IFNγ signaling integrity in colorectal cancer immunity and immunotherapy60
The use of supercytokines, immunocytokines, engager cytokines, and other synthetic cytokines in immunotherapy60
The roles of microglia in viral encephalitis: from sensome to therapeutic targeting59
The soluble glycoprotein NMB (GPNMB) produced by macrophages induces cancer stemness and metastasis via CD44 and IL-3356
Protein N-myristoylation: functions and mechanisms in control of innate immunity56
Regulation of natural killer cell activity by glucocorticoids, serotonin, dopamine, and epinephrine56
Dynamic immune profiling identifies the stronger graft-versus-leukemia (GVL) effects with haploidentical allografts compared to HLA-matched stem cell transplantation55
Tissue-specific Tregs in cancer metastasis: opportunities for precision immunotherapy53
Identification of druggable inhibitory immune checkpoints on Natural Killer cells in COVID-1953
OTUD5 promotes innate antiviral and antitumor immunity through deubiquitinating and stabilizing STING51
Protein synthesis, degradation, and energy metabolism in T cell immunity51
Recombinant vaccine containing an RBD-Fc fusion induced protection against SARS-CoV-2 in nonhuman primates and mice51
Clinical development of CAR T cell therapy in China: 2020 update48
Biology and pathology of the uterine microenvironment and its natural killer cells48
Innate lymphocytes: pathogenesis and therapeutic targets of liver diseases and cancer47
Diet, lipids, and antitumor immunity47
A novel CD4+ CTL subtype characterized by chemotaxis and inflammation is involved in the pathogenesis of Graves’ orbitopathy46
Dynamics of the SARS-CoV-2 antibody response up to 10 months after infection45
SARS-CoV-2 infection in K18-ACE2 transgenic mice replicates human pulmonary disease in COVID-1945
The therapeutic implications of immunosuppressive tumor aerobic glycolysis45
Potential contribution of increased soluble IL-2R to lymphopenia in COVID-19 patients44
Characterization of SARS-CoV-2-specific humoral immunity and its potential applications and therapeutic prospects43
Ticagrelor inhibits the NLRP3 inflammasome to protect against inflammatory disease independent of the P2Y12 signaling pathway43
Cellular and molecular mechanisms breaking immune tolerance in inborn errors of immunity43
Severe COVID-19 patients exhibit an ILC2 NKG2D+ population in their impaired ILC compartment43
SARS-CoV-2-specific T cell immunity to structural proteins in inactivated COVID-19 vaccine recipients42
Chimeric antigen receptor- and natural killer cell receptor-engineered innate killer cells in cancer immunotherapy41
SARS-CoV-2 interaction with Siglec-1 mediates trans-infection by dendritic cells41
Systematic evaluation of IgG responses to SARS-CoV-2 spike protein-derived peptides for monitoring COVID-19 patients40
Epigenetics in modulating immune functions of stromal and immune cells in the tumor microenvironment40
Delta variant (B.1.617.2) sublineages do not show increased neutralization resistance40
The innate immune effector ISG12a promotes cancer immunity by suppressing the canonical Wnt/β-catenin signaling pathway39
Systemically comparing host immunity between survived and deceased COVID-19 patients39
Immune monitoring of interleukin-7 compassionate use in a critically ill COVID-19 patient39
Microenvironmental influences on T cell immunity in cancer and inflammation39
Metabolic programming in dendritic cells tailors immune responses and homeostasis39
Interleukin-6 mediates neutrophil mobilization from bone marrow in pulmonary hypertension38
CD40 stimulation as a molecular adjuvant for cancer vaccines and other immunotherapies38
Reprogramming cholesterol metabolism in macrophages and its role in host defense against cholesterol-dependent cytolysins37
Safety, immunogenicity, and protection provided by unadjuvanted and adjuvanted formulations of a recombinant plant-derived virus-like particle vaccine candidate for COVID-19 in nonhuman primates36
Potentiation of NETs release is novel characteristic of TREM-1 activation and the pharmacological inhibition of TREM-1 could prevent from the deleterious consequences of NETs release in sepsis35
Cross-reactive antibody immunity against SARS-CoV-2 in children and adults35
IL-33 in COVID-19: friend or foe?34
NK cell dysfunction in patients with COVID-1934
Antigen presentation, autoantibody production, and therapeutic targets in autoimmune liver disease34
Multiomics: unraveling the panoramic landscapes of SARS-CoV-2 infection34
sTREM-1 is a specific biomarker of TREM-1 pathway activation33
Circular RNA circZbtb20 maintains ILC3 homeostasis and function via Alkbh5-dependent m6A demethylation of Nr4a1 mRNA33
Inflammatory processes in the liver: divergent roles in homeostasis and pathology33
Transcription tipping points for T follicular helper cell and T-helper 1 cell fate commitment33
Sepsis-associated severe interleukin-6 storm in critical coronavirus disease 201933
Inhibition of CCL2 by bindarit alleviates diabetes-associated periodontitis by suppressing inflammatory monocyte infiltration and altering macrophage properties33
Manganese enhances the antitumor function of CD8+ T cells by inducing type I interferon production32
Regulation of antitumor immunity by inflammation-induced epigenetic alterations32
The deubiquitinase OTUD1 inhibits colonic inflammation by suppressing RIPK1-mediated NF-κB signaling31
Kidney GATA3+ regulatory T cells play roles in the convalescence stage after antibody-mediated renal injury31
Neutralization of the SARS-CoV-2 Delta variant after heterologous and homologous BNT162b2 or ChAdOx1 nCoV-19 vaccination31
STING signaling activation inhibits HBV replication and attenuates the severity of liver injury and HBV-induced fibrosis31
Downregulated miR-451a as a feature of the plasma cfRNA landscape reveals regulatory networks of IL-6/IL-6R-associated cytokine storms in COVID-19 patients30
Supplying the trip to antibody production—nutrients, signaling, and the programming of cellular metabolism in the mature B lineage29
Hepatitis B virus evades immune recognition via RNA adenosine deaminase ADAR1-mediated viral RNA editing in hepatocytes29
CD147 regulates antitumor CD8+ T-cell responses to facilitate tumor-immune escape28
FNDC4 and FNDC5 reduce SARS-CoV-2 entry points and spike glycoprotein S1-induced pyroptosis, apoptosis, and necroptosis in human adipocytes28
Local and systemic effects of IL-17 in joint inflammation: a historical perspective from discovery to targeting28
Autophagy receptor CCDC50 tunes the STING-mediated interferon response in viral infections and autoimmune diseases26
Efficient IL-2R signaling differentially affects the stability, function, and composition of the regulatory T-cell pool26
Immunometabolism at the intersection of metabolic signaling, cell fate, and systems immunology26
The spike protein of SARS-CoV-2 variant A.30 is heavily mutated and evades vaccine-induced antibodies with high efficiency25
Paving the way towards an effective treatment for multiple sclerosis: advances in cell therapy25
PD-L1+ exosomes from bone marrow-derived cells of tumor-bearing mice inhibit antitumor immunity25
Safety and immunogenicity of a SARS-CoV-2 inactivated vaccine in patients with chronic hepatitis B virus infection25
Systems-based approaches to study immunometabolism25
IL-17 sustains the plasma cell response via p38-mediated Bcl-xL RNA stability in lupus pathogenesis25
Reactivation of latent tuberculosis with TNF inhibitors: critical role of the beta 2 chain of the IL-12 receptor24
Adaptive immunity at the crossroads of autophagy and metabolism24
Cell cycle-related kinase reprograms the liver immune microenvironment to promote cancer metastasis24
Synthetic vitamin K analogs inhibit inflammation by targeting the NLRP3 inflammasome23
Differential efficiencies to neutralize the novel mutants B.1.1.7 and 501Y.V2 by collected sera from convalescent COVID-19 patients and RBD nanoparticle-vaccinated rhesus macaques22
HIV-1 Vif suppresses antiviral immunity by targeting STING22
Kupffer cell restoration after partial hepatectomy is mainly driven by local cell proliferation in IL-6-dependent autocrine and paracrine manners22
VRK2 is involved in the innate antiviral response by promoting mitostress-induced mtDNA release22
Taurocholic acid inhibits the response to interferon-α therapy in patients with HBeAg-positive chronic hepatitis B by impairing CD8+ T and NK cell function21
Expanded natural killer cells augment the antimyeloma effect of daratumumab, bortezomib, and dexamethasone in a mouse model21
Variations in killer-cell immunoglobulin-like receptor and human leukocyte antigen genes and immunity to malaria21
Resident and migratory adipose immune cells control systemic metabolism and thermogenesis21
The inhibitor effect of RKIP on inflammasome activation and inflammasome-dependent diseases21
Implications of metabolism-driven myeloid dysfunctions in cancer therapy20
Cytokines that target immune killer cells against tumors20
Exploring innate immunity in cancer immunotherapy: opportunities and challenges20
Meteorin-β/Meteorin like/IL-41 attenuates airway inflammation in house dust mite-induced allergic asthma20
New insights into follicular helper T cell response and regulation in autoimmune pathogenesis19
Single-cell analysis reveals the origins and intrahepatic development of liver-resident IFN-γ-producing γδ T cells19
A recently described type 2 conventional dendritic cell (cDC2) subset mediates inflammation19
Distinct roles but cooperative effect of TLR3/9 agonists and PD-1 blockade in converting the immunotolerant microenvironment of irreversible electroporation-ablated tumors19
No crossreactivity of anti-SARS-CoV-2 spike protein antibodies with Syncytin-119
Dexamethasone ameliorates severe pneumonia but slightly enhances viral replication in the lungs of SARS-CoV-2-infected Syrian hamsters18
STING regulates BCR signaling in normal and malignant B cells18
Changes in the humoral immunity response in SARS-CoV-2 convalescent patients over 8 months18
TGF-β-induced CD4+ FoxP3+ regulatory T cell-derived extracellular vesicles modulate Notch1 signaling through miR-449a and prevent collagen-induced arthritis in a murine model17
SEMA3A-mediated crosstalk between prostate cancer cells and tumor-associated macrophages promotes androgen deprivation therapy resistance17
Opposing regulatory functions of the TIM3 (HAVCR2) signalosome in primary effector T cells as revealed by quantitative interactomics17
The microbiota is dispensable for the early stages of peripheral regulatory T cell induction within mesenteric lymph nodes17
Vaccine booster efficiently inhibits entry of SARS-CoV-2 omicron variant17
SRSF1 plays a critical role in invariant natural killer T cell development and function17
Conventional type 1 dendritic cells protect against age-related adipose tissue dysfunction and obesity17