OOIR: Observatory of International Research

Papers

(The median citation count of Cellular & Molecular Immunology is 17. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-11-01 to 2024-11-01.)

Article	Citations
Necroptosis, pyroptosis and apoptosis: an intricate game of cell death	986
NLRP3 inflammasome activation and cell death	649
Tumor-infiltrating lymphocytes in the immunotherapy era	491
An update on the regulatory mechanisms of NLRP3 inflammasome activation	372
A longitudinal study of SARS-CoV-2-infected patients reveals a high correlation between neutralizing antibodies and COVID-19 severity	267
Neutrophils in chronic inflammatory diseases	246
The blood–brain barrier in systemic infection and inflammation	244
Gut microbiota-derived metabolites in the regulation of host immune responses and immune-related inflammatory diseases	224
Gut microbiome, liver immunology, and liver diseases	216
Dendritic cell migration in inflammation and immunity	210
Regulation of RIG-I-like receptor-mediated signaling: interaction between host and viral factors	208
Control of lymphocyte functions by gut microbiota-derived short-chain fatty acids	201
Increased immune escape of the new SARS-CoV-2 variant of concern Omicron	180
Metabolism of tissue macrophages in homeostasis and pathology	180
Immunobiology and immunotherapy of HCC: spotlight on innate and innate-like immune cells	178
Manganese salts function as potent adjuvants	157
SARS-CoV-2-specific T cells in infection and vaccination	134
Activation or exhaustion of CD8+ T cells in patients with COVID-19	131
SARS-CoV-2 ORF10 suppresses the antiviral innate immune response by degrading MAVS through mitophagy	130
Phase I study of CAR-T cells with PD-1 and TCR disruption in mesothelin-positive solid tumors	124
The cutting-edge progress of immune-checkpoint blockade in lung cancer	121
Tumor-associated myeloid cells: diversity and therapeutic targeting	120
Immunological mechanisms and therapeutic targets of fatty liver diseases	118
Dendritic cells in cancer immunology	118
Pathological and molecular examinations of postmortem testis biopsies reveal SARS-CoV-2 infection in the testis and spermatogenesis damage in COVID-19 patients	113

Ubiquitination of SARS-CoV-2 ORF7a promotes antagonism of interferon response	111
Neutralizing antibodies for the prevention and treatment of COVID-19	99
SARS-CoV-2 nsp12 attenuates type I interferon production by inhibiting IRF3 nuclear translocation	98
Enhancing CAR-T cell efficacy in solid tumors by targeting the tumor microenvironment	93
Neutrophils in liver diseases: pathogenesis and therapeutic targets	90
Dendritic cell deficiencies persist seven months after SARS-CoV-2 infection	86
RRx-001 ameliorates inflammatory diseases by acting as a potent covalent NLRP3 inhibitor	86
Emerging SARS-CoV-2 variants reduce neutralization sensitivity to convalescent sera and monoclonal antibodies	85
Low serum neutralizing anti-SARS-CoV-2 S antibody levels in mildly affected COVID-19 convalescent patients revealed by two different detection methods	84
Immunopathobiology and therapeutic targets related to cytokines in liver diseases	83
T cell epitopes in SARS-CoV-2 proteins are substantially conserved in the Omicron variant	82
Impact of intracellular innate immune receptors on immunometabolism	82
Pyroptotic macrophages stimulate the SARS-CoV-2-associated cytokine storm	79
Single-cell profiling reveals the trajectories of natural killer cell differentiation in bone marrow and a stress signature induced by acute myeloid leukemia	78
Autoimmmune hepatitis	76
Microglia as hackers of the matrix: sculpting synapses and the extracellular space	75
Construction of a sustainable 3-hydroxybutyrate-producing probiotic Escherichia coli for treatment of colitis	74
The aryl hydrocarbon receptor and the gut–brain axis	73
The use of supercytokines, immunocytokines, engager cytokines, and other synthetic cytokines in immunotherapy	72
Ferritin nanoparticle-based SARS-CoV-2 RBD vaccine induces a persistent antibody response and long-term memory in mice	71
IFNγ signaling integrity in colorectal cancer immunity and immunotherapy	71
T cell immune responses to SARS-CoV-2 and variants of concern (Alpha and Delta) in infected and vaccinated individuals	69
The roles of microglia in viral encephalitis: from sensome to therapeutic targeting	68
HLA class I loss in colorectal cancer: implications for immune escape and immunotherapy	67
Olfactory ecto-mesenchymal stem cell-derived exosomes ameliorate murine Sjögren’s syndrome by modulating the function of myeloid-derived suppressor cells	66
Protein N-myristoylation: functions and mechanisms in control of innate immunity	63
Protein synthesis, degradation, and energy metabolism in T cell immunity	61
Diet, lipids, and antitumor immunity	61
Tissue-specific Tregs in cancer metastasis: opportunities for precision immunotherapy	59
Dynamic immune profiling identifies the stronger graft-versus-leukemia (GVL) effects with haploidentical allografts compared to HLA-matched stem cell transplantation	59
Biology and pathology of the uterine microenvironment and its natural killer cells	56
Recombinant vaccine containing an RBD-Fc fusion induced protection against SARS-CoV-2 in nonhuman primates and mice	55
The therapeutic implications of immunosuppressive tumor aerobic glycolysis	54
Chimeric antigen receptor- and natural killer cell receptor-engineered innate killer cells in cancer immunotherapy	53
Metabolic programming in dendritic cells tailors immune responses and homeostasis	53
A novel CD4+ CTL subtype characterized by chemotaxis and inflammation is involved in the pathogenesis of Graves’ orbitopathy	51
SARS-CoV-2 infection in K18-ACE2 transgenic mice replicates human pulmonary disease in COVID-19	48
Characterization of SARS-CoV-2-specific humoral immunity and its potential applications and therapeutic prospects	48
Microenvironmental influences on T cell immunity in cancer and inflammation	47
Dynamics of the SARS-CoV-2 antibody response up to 10 months after infection	47
Cellular and molecular mechanisms breaking immune tolerance in inborn errors of immunity	46
CD40 stimulation as a molecular adjuvant for cancer vaccines and other immunotherapies	45
Severe COVID-19 patients exhibit an ILC2 NKG2D+ population in their impaired ILC compartment	44
Systematic evaluation of IgG responses to SARS-CoV-2 spike protein-derived peptides for monitoring COVID-19 patients	42
The deubiquitinase OTUD1 inhibits colonic inflammation by suppressing RIPK1-mediated NF-κB signaling	42
SARS-CoV-2-specific T cell immunity to structural proteins in inactivated COVID-19 vaccine recipients	42
Interleukin-6 mediates neutrophil mobilization from bone marrow in pulmonary hypertension	41
SARS-CoV-2 interaction with Siglec-1 mediates trans-infection by dendritic cells	41
Reprogramming cholesterol metabolism in macrophages and its role in host defense against cholesterol-dependent cytolysins	41
Delta variant (B.1.617.2) sublineages do not show increased neutralization resistance	40

Safety, immunogenicity, and protection provided by unadjuvanted and adjuvanted formulations of a recombinant plant-derived virus-like particle vaccine candidate for COVID-19 in nonhuman primates	40
Potentiation of NETs release is novel characteristic of TREM-1 activation and the pharmacological inhibition of TREM-1 could prevent from the deleterious consequences of NETs release in sepsis	40
Inflammatory processes in the liver: divergent roles in homeostasis and pathology	39
Supplying the trip to antibody production—nutrients, signaling, and the programming of cellular metabolism in the mature B lineage	38
STING signaling activation inhibits HBV replication and attenuates the severity of liver injury and HBV-induced fibrosis	38
FNDC4 and FNDC5 reduce SARS-CoV-2 entry points and spike glycoprotein S1-induced pyroptosis, apoptosis, and necroptosis in human adipocytes	37
Cross-reactive antibody immunity against SARS-CoV-2 in children and adults	37
IL-33 in COVID-19: friend or foe?	37
Resident and migratory adipose immune cells control systemic metabolism and thermogenesis	36
Immunometabolism at the intersection of metabolic signaling, cell fate, and systems immunology	36
Circular RNA circZbtb20 maintains ILC3 homeostasis and function via Alkbh5-dependent m6A demethylation of Nr4a1 mRNA	35
NK cell dysfunction in patients with COVID-19	35
Multiomics: unraveling the panoramic landscapes of SARS-CoV-2 infection	35
sTREM-1 is a specific biomarker of TREM-1 pathway activation	35
Regulation of antitumor immunity by inflammation-induced epigenetic alterations	34
Local and systemic effects of IL-17 in joint inflammation: a historical perspective from discovery to targeting	32
Neutralization of the SARS-CoV-2 Delta variant after heterologous and homologous BNT162b2 or ChAdOx1 nCoV-19 vaccination	32
Downregulated miR-451a as a feature of the plasma cfRNA landscape reveals regulatory networks of IL-6/IL-6R-associated cytokine storms in COVID-19 patients	31
Efficient IL-2R signaling differentially affects the stability, function, and composition of the regulatory T-cell pool	30
Hepatitis B virus evades immune recognition via RNA adenosine deaminase ADAR1-mediated viral RNA editing in hepatocytes	30
Systems-based approaches to study immunometabolism	30
Autophagy receptor CCDC50 tunes the STING-mediated interferon response in viral infections and autoimmune diseases	30
Paving the way towards an effective treatment for multiple sclerosis: advances in cell therapy	30
The spike protein of SARS-CoV-2 variant A.30 is heavily mutated and evades vaccine-induced antibodies with high efficiency	30
CD147 regulates antitumor CD8+ T-cell responses to facilitate tumor-immune escape	29
Adaptive immunity at the crossroads of autophagy and metabolism	29
HIV-1 Vif suppresses antiviral immunity by targeting STING	28
Reactivation of latent tuberculosis with TNF inhibitors: critical role of the beta 2 chain of the IL-12 receptor	27
Exploring innate immunity in cancer immunotherapy: opportunities and challenges	26
Kupffer cell restoration after partial hepatectomy is mainly driven by local cell proliferation in IL-6-dependent autocrine and paracrine manners	26
Safety and immunogenicity of a SARS-CoV-2 inactivated vaccine in patients with chronic hepatitis B virus infection	25
Meteorin-β/Meteorin like/IL-41 attenuates airway inflammation in house dust mite-induced allergic asthma	24
VRK2 is involved in the innate antiviral response by promoting mitostress-induced mtDNA release	24
Expanded natural killer cells augment the antimyeloma effect of daratumumab, bortezomib, and dexamethasone in a mouse model	22
Distinct roles but cooperative effect of TLR3/9 agonists and PD-1 blockade in converting the immunotolerant microenvironment of irreversible electroporation-ablated tumors	22
Differential efficiencies to neutralize the novel mutants B.1.1.7 and 501Y.V2 by collected sera from convalescent COVID-19 patients and RBD nanoparticle-vaccinated rhesus macaques	22
Taurocholic acid inhibits the response to interferon-α therapy in patients with HBeAg-positive chronic hepatitis B by impairing CD8+ T and NK cell function	22
Single-cell analysis reveals the origins and intrahepatic development of liver-resident IFN-γ-producing γδ T cells	21
New insights into follicular helper T cell response and regulation in autoimmune pathogenesis	21
SEMA3A-mediated crosstalk between prostate cancer cells and tumor-associated macrophages promotes androgen deprivation therapy resistance	20
Placenta-derived IL-32β activates neutrophils to promote preeclampsia development	20
No crossreactivity of anti-SARS-CoV-2 spike protein antibodies with Syncytin-1	20
Dexamethasone ameliorates severe pneumonia but slightly enhances viral replication in the lungs of SARS-CoV-2-infected Syrian hamsters	20
SRSF1 plays a critical role in invariant natural killer T cell development and function	19
The microbiota is dispensable for the early stages of peripheral regulatory T cell induction within mesenteric lymph nodes	19
miR-23a/b suppress cGAS-mediated innate and autoimmunity	19
Vaccine booster efficiently inhibits entry of SARS-CoV-2 omicron variant	18
TGF-β-induced CD4+ FoxP3+ regulatory T cell-derived extracellular vesicles modulate Notch1 signaling through miR-449a and prevent collagen-induced arthritis in a murine model	18
Priming of NLRP3 inflammasome activation by Msn kinase MINK1 in macrophages	18
The ubiquitin ligase Peli1 inhibits ICOS and thereby Tfh-mediated immunity	18
Conventional type 1 dendritic cells protect against age-related adipose tissue dysfunction and obesity	18
Changes in the humoral immunity response in SARS-CoV-2 convalescent patients over 8 months	18
Self-activation of Vγ9Vδ2 T cells by exogenous phosphoantigens involves TCR and butyrophilins	18
Opposing regulatory functions of the TIM3 (HAVCR2) signalosome in primary effector T cells as revealed by quantitative interactomics	17
ACE2 expression is regulated by AhR in SARS-CoV-2-infected macaques	17
Induced regulatory T cells suppress Tc1 cells through TGF-β signaling to ameliorate STZ-induced type 1 diabetes mellitus	17