Acta Pharmacologica Sinica

Article	Citations
Natural products: potential treatments for cisplatin-induced nephrotoxicity	174
Endothelial dysfunction in COVID-19: an overview of evidence, biomarkers, mechanisms and potential therapies	171
Mitochondrial-derived damage-associated molecular patterns amplify neuroinflammation in neurodegenerative diseases	99
Deletion of TLR4 attenuates lipopolysaccharide-induced acute liver injury by inhibiting inflammation and apoptosis	88
Luteolin alleviates cognitive impairment in Alzheimer’s disease mouse model via inhibiting endoplasmic reticulum stress-dependent neuroinflammation	85
Baicalein ameliorates ulcerative colitis by improving intestinal epithelial barrier via AhR/IL-22 pathway in ILC3s	78
ATF3 contributes to brucine-triggered glioma cell ferroptosis via promotion of hydrogen peroxide and iron	76
Wogonin protects glomerular podocytes by targeting Bcl-2-mediated autophagy and apoptosis in diabetic kidney disease	72
Mutations in key driver genes of pancreatic cancer: molecularly targeted therapies and other clinical implications	72
Structure genomics of SARS-CoV-2 and its Omicron variant: drug design templates for COVID-19	68
Mitochondrial aldehyde dehydrogenase (ALDH2) rescues cardiac contractile dysfunction in an APP/PS1 murine model of Alzheimer’s disease via inhibition of ACSL4-dependent ferroptosis	64
The glycolytic process in endothelial cells and its implications	64
New therapeutics beyond amyloid-β and tau for the treatment of Alzheimer’s disease	62
NOD-like receptors in autoimmune diseases	61
DL-3-n-butylphthalide ameliorates diabetes-associated cognitive decline by enhancing PI3K/Akt signaling and suppressing oxidative stress	60
Pyroptosis and pyroptosis-inducing cancer drugs	59
AlphaFold2 versus experimental structures: evaluation on G protein-coupled receptors	59
Ferroptosis inhibitor liproxstatin-1 alleviates metabolic dysfunction-associated fatty liver disease in mice: potential involvement of PANoptosis	57
Blueberry-derived exosomes-like nanoparticles ameliorate nonalcoholic fatty liver disease by attenuating mitochondrial oxidative stress	56
Therapeutic potential of colchicine in cardiovascular medicine: a pharmacological review	55
Current advances in the use of exosomes, liposomes, and bioengineered hybrid nanovesicles in cancer detection and therapy	55
STING inhibitor ameliorates LPS-induced ALI by preventing vascular endothelial cells-mediated immune cells chemotaxis and adhesion	53
Bile acid and receptors: biology and drug discovery for nonalcoholic fatty liver disease	51
Salvianolic acid A prevented cerebrovascular endothelial injury caused by acute ischemic stroke through inhibiting the Src signaling pathway	49
Metformin promotes microglial cells to facilitate myelin debris clearance and accelerate nerve repairment after spinal cord injury	49

Targeting HMGB1 for the treatment of sepsis and sepsis-induced organ injury	49
Ginsenoside Rb1 alleviates diabetic kidney podocyte injury by inhibiting aldose reductase activity	48
Catalpol improves impaired neurovascular unit in ischemic stroke rats via enhancing VEGF-PI3K/AKT and VEGF-MEK1/2/ERK1/2 signaling	47
Tu-San-Qi (Gynura japonica): the culprit behind pyrrolizidine alkaloid-induced liver injury in China	47
A multi-targeting drug design strategy for identifying potent anti-SARS-CoV-2 inhibitors	47
Celastrol induces lipophagy via the LXRα/ABCA1 pathway in clear cell renal cell carcinoma	45
Tetrandrine alleviates silicosis by inhibiting canonical and non-canonical NLRP3 inflammasome activation in lung macrophages	44
Berberine alleviates visceral hypersensitivity in rats by altering gut microbiome and suppressing spinal microglial activation	44
Disulfiram-loaded lactoferrin nanoparticles for treating inflammatory diseases	43
Multi-compound and drug-combination pharmacokinetic research on Chinese herbal medicines	43
Safety, tolerability, and pharmacokinetics of VV116, an oral nucleoside analog against SARS-CoV-2, in Chinese healthy subjects	43
Benzimidazoles induce concurrent apoptosis and pyroptosis of human glioblastoma cells via arresting cell cycle	43
Ferroptosis in viral infection: the unexplored possibility	42
Discovery of potential small molecular SARS-CoV-2 entry blockers targeting the spike protein	42
Diterbutyl phthalate attenuates osteoarthritis in ACLT mice via suppressing ERK/c-fos/NFATc1 pathway, and subsequently inhibiting subchondral osteoclast fusion	42
Mesenchymal stem cells in fibrotic diseases—the two sides of the same coin	42
Widespread myocardial dysfunction in COVID-19 patients detected by myocardial strain imaging using 2-D speckle-tracking echocardiography	40
Cinnamaldehyde induces autophagy-mediated cell death through ER stress and epigenetic modification in gastric cancer cells	39
Pretreatment with chitosan oligosaccharides attenuate experimental severe acute pancreatitis via inhibiting oxidative stress and modulating intestinal homeostasis	39
Chitosan oligosaccharide modified liposomes enhance lung cancer delivery of paclitaxel	39
Dapagliflozin attenuates pressure overload-induced myocardial remodeling in mice via activating SIRT1 and inhibiting endoplasmic reticulum stress	39
Structure, regulation, and biological functions of TIGAR and its role in diseases	38
Berberine remodels adipose tissue to attenuate metabolic disorders by activating sirtuin 3	38
Predictive biomarkers of immunotherapy response with pharmacological applications in solid tumors	38
Lp-PLA2 inhibition prevents Ang II-induced cardiac inflammation and fibrosis by blocking macrophage NLRP3 inflammasome activation	37
Pirfenidone ameliorates silica-induced lung inflammation and fibrosis in mice by inhibiting the secretion of interleukin-17A	36
Regulatory T cells in ischemic stroke	36
The m6A demethylase FTO promotes the osteogenesis of mesenchymal stem cells by downregulating PPARG	36
Diosmetin has therapeutic efficacy in colitis regulating gut microbiota, inflammation, and oxidative stress via the circ-Sirt1/Sirt1 axis	36
Surface loading of nanoparticles on engineered or natural erythrocytes for prolonged circulation time: strategies and applications	35
Suppression of the USP10/CCND1 axis induces glioblastoma cell apoptosis	35
Sorafenib triggers ferroptosis via inhibition of HBXIP/SCD axis in hepatocellular carcinoma	34
DrugRep: an automatic virtual screening server for drug repurposing	34
Probiotics protect against RSV infection by modulating the microbiota-alveolar-macrophage axis	34
Gout-associated monosodium urate crystal-induced necrosis is independent of NLRP3 activity but can be suppressed by combined inhibitors for multiple signaling pathways	33
Direct cardio-protection of Dapagliflozin against obesity-related cardiomyopathy via NHE1/MAPK signaling	33
Ethyl ferulate protects against lipopolysaccharide-induced acute lung injury by activating AMPK/Nrf2 signaling pathway	32
Bispecific antibody simultaneously targeting PD1 and HER2 inhibits tumor growth via direct tumor cell killing in combination with PD1/PDL1 blockade and HER2 inhibition	32
Asiatic acid alleviates ischemic myocardial injury in mice by modulating mitophagy- and glycophagy-based energy metabolism	32
Angiogenesis after ischemic stroke	32
GPR84 signaling promotes intestinal mucosal inflammation via enhancing NLRP3 inflammasome activation in macrophages	32
Ginsenoside Rg1 in neurological diseases: From bench to bedside	31
Trilobatin rescues cognitive impairment of Alzheimer’s disease by targeting HMGB1 through mediating SIRT3/SOD2 signaling pathway	30
Reduced nicotinamide adenine dinucleotide phosphate in redox balance and diseases: a friend or foe?	30
FOXO3a protects glioma cells against temozolomide-induced DNA double strand breaks via promotion of BNIP3-mediated mitophagy	30
Lipid/PAA-coated mesoporous silica nanoparticles for dual-pH-responsive codelivery of arsenic trioxide/paclitaxel against breast cancer cells	30
Caspase-11 promotes NLRP3 inflammasome activation via the cleavage of pannexin1 in acute kidney disease	29
Updates on novel pharmacotherapeutics for the treatment of nonalcoholic steatohepatitis	29
Inhibition of AXL enhances chemosensitivity of human ovarian cancer cells to cisplatin via decreasing glycolysis	29
Interleukin-17 upregulation participates in the pathogenesis of heart failure in mice via NF-κB-dependent suppression of SERCA2a and Cav1.2 expression	29

6-Gingerol protects against cardiac remodeling by inhibiting the p38 mitogen-activated protein kinase pathway	28
Engineered nanomedicines block the PD-1/PD-L1 axis for potentiated cancer immunotherapy	28
Novel CDK9 inhibitor oroxylin A promotes wild-type P53 stability and prevents hepatocellular carcinoma progression by disrupting both MDM2 and SIRT1 signaling	28
Ginsenoside Rb1 alleviates colitis in mice via activation of endoplasmic reticulum-resident E3 ubiquitin ligase Hrd1 signaling pathway	28
Intrarenal 1-methoxypyrene, an aryl hydrocarbon receptor agonist, mediates progressive tubulointerstitial fibrosis in mice	28
Methylene blue prevents osteoarthritis progression and relieves pain in rats via upregulation of Nrf2/PRDX1	27
TRIM25 activates AKT/mTOR by inhibiting PTEN via K63-linked polyubiquitination in non-small cell lung cancer	27
Lupeol protects against cardiac hypertrophy via TLR4-PI3K-Akt-NF-κB pathways	27
Artemisinin improves neurocognitive deficits associated with sepsis by activating the AMPK axis in microglia	27
Druggability of lipid metabolism modulation against renal fibrosis	27
Clinical characteristics and related risk factors of disease severity in 101 COVID-19 patients hospitalized in Wuhan, China	27
Regulated cell death pathways in cardiomyopathy	26
Triptolide suppresses the growth and metastasis of non-small cell lung cancer by inhibiting β-catenin-mediated epithelial–mesenchymal transition	26
Apolipoprotein C1 promotes glioblastoma tumorigenesis by reducing KEAP1/NRF2 and CBS-regulated ferroptosis	26
Bmal1 inhibits phenotypic transformation of hepatic stellate cells in liver fibrosis via IDH1/α-KG-mediated glycolysis	26
Activating α7nAChR ameliorates abdominal aortic aneurysm through inhibiting pyroptosis mediated by NLRP3 inflammasome	25
BMSC-derived exosomes ameliorate sulfur mustard-induced acute lung injury by regulating the GPRC5A–YAP axis	25
Extracellular vesicles in vascular remodeling	25
CDER167, a dual inhibitor of URAT1 and GLUT9, is a novel and potent uricosuric candidate for the treatment of hyperuricemia	25
PRMT5 confers lipid metabolism reprogramming, tumour growth and metastasis depending on the SIRT7-mediated desuccinylation of PRMT5 K387 in tumours	24
NADPH is superior to NADH or edaravone in ameliorating metabolic disturbance and brain injury in ischemic stroke	24
Ginsenoside Rg1 exerts neuroprotective effects in 3-nitropronpionic acid-induced mouse model of Huntington’s disease via suppressing MAPKs and NF-κB pathways in the striatum	24
Paris saponin VII, a Hippo pathway activator, induces autophagy and exhibits therapeutic potential against human breast cancer cells	24
Bergenin, a PPARγ agonist, inhibits Th17 differentiation and subsequent neutrophilic asthma by preventing GLS1-dependent glutaminolysis	24
Cell senescence induced by toxic interaction between α-synuclein and iron precedes nigral dopaminergic neuron loss in a mouse model of Parkinson’s disease	24
Roxithromycin attenuates bleomycin-induced pulmonary fibrosis by targeting senescent cells	23
CDDO-Im ameliorates osteoarthritis and inhibits chondrocyte apoptosis in mice via enhancing Nrf2-dependent autophagy	23
Hepatocyte-derived VEGFA accelerates the progression of non-alcoholic fatty liver disease to hepatocellular carcinoma via activating hepatic stellate cells	23
Pantoprazole ameliorates liver fibrosis and suppresses hepatic stellate cell activation in bile duct ligation rats by promoting YAP degradation	23
Caffeine promotes angiogenesis through modulating endothelial mitochondrial dynamics	23
Fatty acid-binding protein 7 triggers α-synuclein oligomerization in glial cells and oligodendrocytes associated with oxidative stress	23
Kanglexin delays heart aging by promoting mitophagy	23
Inhibition of histamine receptor H3 suppresses the growth and metastasis of human non-small cell lung cancer cells via inhibiting PI3K/Akt/mTOR and MEK/ERK signaling pathways and blocking EMT	23
Pharmacokinetics-based identification of pseudoaldosterogenic compounds originating from Glycyrrhiza uralensis roots (Gancao) after dosing LianhuaQingwen capsule	22
ADH1C inhibits progression of colorectal cancer through the ADH1C/PHGDH /PSAT1/serine metabolic pathway	22
FXR: structures, biology, and drug development for NASH and fibrosis diseases	22
Neuronal chemokine-like-factor 1 (CKLF1) up-regulation promotes M1 polarization of microglia in rat brain after stroke	22
Aspirin triggers ferroptosis in hepatocellular carcinoma cells through restricting NF-κB p65-activated SLC7A11 transcription	22
A GLP-1 analog lowers ER stress and enhances protein folding to ameliorate homocysteine-induced endothelial dysfunction	22
Cepharanthine sensitizes human triple negative breast cancer cells to chemotherapeutic agent epirubicin via inducing cofilin oxidation-mediated mitochondrial fission and apoptosis	22
Notoginsenoside R1 protects against myocardial ischemia/reperfusion injury in mice via suppressing TAK1-JNK/p38 signaling	22
The adipokine orosomucoid alleviates adipose tissue fibrosis via the AMPK pathway	21
Inhibition of miR-135a-5p attenuates vascular smooth muscle cell proliferation and vascular remodeling in hypertensive rats	21
Pramipexole inhibits astrocytic NLRP3 inflammasome activation via Drd3-dependent autophagy in a mouse model of Parkinson’s disease	21
Fibronectin type III domain-containing 5 in cardiovascular and metabolic diseases: a promising biomarker and therapeutic target	21
Integrative phosphatidylcholine metabolism through phospholipase A2 in rats with chronic kidney disease	21
Hernandezine induces autophagic cell death in human pancreatic cancer cells via activation of the ROS/AMPK signaling pathway	21
ZEB1 serves an oncogenic role in the tumourigenesis of HCC by promoting cell proliferation, migration, and inhibiting apoptosis via Wnt/β-catenin signaling pathway	21
Immune-based combination therapy to convert immunologically cold tumors into hot tumors: an update and new insights	21
Anti-PD-L1 mediating tumor-targeted codelivery of liposomal irinotecan/JQ1 for chemo-immunotherapy	21
MicroRNA-214 contributes to Ang II-induced cardiac hypertrophy by targeting SIRT3 to provoke mitochondrial malfunction	20
Role of the mTOR-autophagy-ER stress pathway in high fructose-induced metabolic-associated fatty liver disease	20
Urolithin A ameliorates obesity-induced metabolic cardiomyopathy in mice via mitophagy activation	20
Ganoderic acid alleviates chemotherapy-induced fatigue in mice bearing colon tumor	20
G3BP1 promotes human breast cancer cell proliferation through coordinating with GSK-3β and stabilizing β-catenin	20
TFEB, a master regulator of autophagy and biogenesis, unexpectedly promotes apoptosis in response to the cyclopentenone prostaglandin 15d-PGJ2	20
PINK1 overexpression prevents forskolin-induced tau hyperphosphorylation and oxidative stress in a rat model of Alzheimer’s disease	20
Modulating mitochondrial dynamics attenuates cardiac ischemia-reperfusion injury in prediabetic rats	20
Proteomic characterization of post-translational modifications in drug discovery	19
Inhibition of drug-metabolizing enzymes by Jingyin granules: implications of herb–drug interactions in antiviral therapy	19
cGAS and cancer therapy: a double-edged sword	19
Novel insights into NOD-like receptors in renal diseases	19
Paeoniflorin ameliorates ischemic injury in rat brain via inhibiting cytochrome c/caspase3/HDAC4 pathway	19
Corynoxine B derivative CB6 prevents Parkinsonian toxicity in mice by inducing PIK3C3 complex-dependent autophagy	19
Function and structure of bradykinin receptor 2 for drug discovery	19
The small molecule chemical compound cinobufotalin attenuates resistance to DDP by inducing ENKUR expression to suppress MYH9-mediated c-Myc deubiquitination in lung adenocarcinoma	19
Tetramethylpyrazine prevents liver fibrotic injury in mice by targeting hepatocyte-derived and mitochondrial DNA-enriched extracellular vesicles	19
Harmine is an effective therapeutic small molecule for the treatment of cardiac hypertrophy	18
Pseudoginsenoside-F11 attenuates cognitive dysfunction and tau phosphorylation in sporadic Alzheimer’s disease rat model	18
GDF11 promotes wound healing in diabetic mice via stimulating HIF-1ɑ-VEGF/SDF-1ɑ-mediated endothelial progenitor cell mobilization and neovascularization	18
A novel tricyclic BTK inhibitor suppresses B cell responses and osteoclastic bone erosion in rheumatoid arthritis	18
PPARα agonist fenofibrate relieves acquired resistance to gefitinib in non-small cell lung cancer by promoting apoptosis via PPARα/AMPK/AKT/FoxO1 pathway	18
Exogenous glutathione exerts a therapeutic effect in ischemic stroke rats by interacting with intrastriatal dopamine	18
Sulforaphane activates anti-inflammatory microglia, modulating stress resilience associated with BDNF transcription	18
1,2,4-Trimethoxybenzene selectively inhibits NLRP3 inflammasome activation and attenuates experimental autoimmune encephalomyelitis	18
Pharmacokinetics, mass balance, and metabolism of [14C]vicagrel, a novel irreversible P2Y12 inhibitor in humans	18
Dihydroartemisinin suppresses renal fibrosis in mice by inhibiting DNA-methyltransferase 1 and increasing Klotho	17
The novel STAT3 inhibitor WZ-2-033 causes regression of human triple-negative breast cancer and gastric cancer xenografts	17
Autophagy inhibitors increase the susceptibility of KRAS-mutant human colorectal cancer cells to a combined treatment of 2-deoxy-D-glucose and lovastatin	17
Bergapten inhibits NLRP3 inflammasome activation and pyroptosis via promoting mitophagy	17

Discovery of a novel nonsteroidal selective glucocorticoid receptor modulator by virtual screening and bioassays	17
Vagal-α7nAChR signaling is required for lung anti-inflammatory responses and arginase 1 expression during an influenza infection	17
Calcipotriol abrogates cancer-associated fibroblast-derived IL-8-mediated oxaliplatin resistance in gastric cancer cells via blocking PI3K/Akt signaling	17
Sulforaphane ameliorates non-alcoholic fatty liver disease in mice by promoting FGF21/FGFR1 signaling pathway	17
Development of a nanobody-based immunoassay for the sensitive detection of fibrinogen-like protein 1	17
Helichrysetin inhibits gastric cancer growth by targeting c-Myc/PDHK1 axis-mediated energy metabolism reprogramming	17
Caffeic acid phenethyl ester suppresses intestinal FXR signaling and ameliorates nonalcoholic fatty liver disease by inhibiting bacterial bile salt hydrolase activity	17
Melatonin ameliorates bleomycin-induced pulmonary fibrosis via activating NRF2 and inhibiting galectin-3 expression	17
Selective EZH2 inhibitor zld1039 alleviates inflammation in cisplatin-induced acute kidney injury partially by enhancing RKIP and suppressing NF-κB p65 pathway	17
Danshensu alleviates pseudo-typed SARS-CoV-2 induced mouse acute lung inflammation	17
Epac activation ameliorates tubulointerstitial inflammation in diabetic nephropathy	17
Protein O-GlcNAcylation in cardiovascular diseases	17
Discovery of SARS-CoV-2-E channel inhibitors as antiviral candidates	17
Glibenclamide alleviates β adrenergic receptor activation-induced cardiac inflammation	17
Mass spectrometry imaging: new eyes on natural products for drug research and development	17
Regulation of toll-like receptor (TLR) signaling pathways in atherosclerosis: from mechanisms to targeted therapeutics	16
Chronic infusion of ELABELA alleviates vascular remodeling in spontaneously hypertensive rats via anti-inflammatory, anti-oxidative and anti-proliferative effects	16
Mitochondria homeostasis: Biology and involvement in hepatic steatosis to NASH	16
β-arrestin 2 is essential for fluoxetine-mediated promotion of hippocampal neurogenesis in a mouse model of depression	16
3,4-dihydroxytoluene, a metabolite of rutin, suppresses the progression of nonalcoholic fatty liver disease in mice by inhibiting p300 histone acetyltransferase activity	16
Humanized cerebral organoids-based ischemic stroke model for discovering of potential anti-stroke agents	16
KCNN4-mediated Ca2+/MET/AKT axis is promising for targeted therapy of pancreatic ductal adenocarcinoma	16
NASH: regulatory considerations for clinical drug development and U.S. FDA approval	16
Iptakalim improves cerebral microcirculation in mice after ischemic stroke by inhibiting pericyte contraction	16
Rictor/mTORC2 involves mitochondrial function in ES cells derived cardiomyocytes via mitochondrial Connexin 43	16
BAFF, involved in B cell activation through the NF-κB pathway, is related to disease activity and bone destruction in rheumatoid arthritis	16
Roxadustat alleviates nitroglycerin-induced migraine in mice by regulating HIF-1α/NF-κB/inflammation pathway	16
Upregulation of acid sensing ion channel 1a (ASIC1a) by hydrogen peroxide through the JNK pathway	15
The double faced role of xanthine oxidoreductase in cancer	15
Long-term administration of salvianolic acid A promotes endogenous neurogenesis in ischemic stroke rats through activating Wnt3a/GSK3β/β-catenin signaling pathway	15
Tetrahydroberberrubine retards heart aging in mice by promoting PHB2-mediated mitophagy	15
Paraptosis: a non-classical paradigm of cell death for cancer therapy	15
Chemotherapy-induced metastasis: molecular mechanisms and clinical therapies	15
Ainsliadimer C, a disesquiterpenoid isolated from Ainsliaea macrocephala, ameliorates inflammatory responses in adipose tissue via Sirtuin 1-NLRP3 inflammasome axis	15
Ginsenoside 20(S)-Rh2 promotes cellular pharmacokinetics and intracellular antibacterial activity of levofloxacin against Staphylococcus aureus through drug efflux inhibition and subcellular stabiliza	15
Antiatherosclerotic effect of dehydrocorydaline on ApoE−/− mice: inhibition of macrophage inflammation	15
Discovery of novel antagonists targeting the DNA binding domain of androgen receptor by integrated docking-based virtual screening and bioassays	15
Neuronal K+-Cl- cotransporter KCC2 as a promising drug target for epilepsy treatment	15
EM-2 inhibited autophagy and promoted G2/M phase arrest and apoptosis by activating the JNK pathway in hepatocellular carcinoma cells	15
The baroreflex afferent pathway plays a critical role in H2S-mediated autonomic control of blood pressure regulation under physiological and hypertensive conditions	15
Current strategies and progress for targeting the “undruggable” transcription factors	15
TGR5 agonist inhibits intestinal epithelial cell apoptosis via cAMP/PKA/c-FLIP/JNK signaling pathway and ameliorates dextran sulfate sodium-induced ulcerative colitis	14
Silibinin relieves UVB-induced apoptosis of human skin cells by inhibiting the YAP-p73 pathway	14
MC1R and melanin-based molecular probes for theranostic of melanoma and beyond	14
Pharmacological inhibition of MyD88 suppresses inflammation in tubular epithelial cells and prevents diabetic nephropathy in experimental mice	14
Cardiomyocyte peroxisome proliferator-activated receptor α is essential for energy metabolism and extracellular matrix homeostasis during pressure overload-induced cardiac remodeling	14
PXR mediates mifepristone-induced hepatomegaly in mice	14
Chemistry and bioactivity of secondary metabolites from South China Sea marine fauna and flora: recent research advances and perspective	14
Flavokawain B alleviates LPS-induced acute lung injury via targeting myeloid differentiation factor 2	14
MANF ameliorates DSS-induced mouse colitis via restricting Ly6ChiCX3CR1int macrophage transformation and suppressing CHOP-BATF2 signaling pathway	14
Connexin 43: insights into candidate pathological mechanisms of depression and its implications in antidepressant therapy	14
FK228 potentiates topotecan activity against small cell lung cancer cells via induction of SLFN11	14
Long-term running exercise alleviates cognitive dysfunction in APP/PSEN1 transgenic mice via enhancing brain lysosomal function	14
Dezocine as a potent analgesic: overview of its pharmacological characterization	14
Bis-isatin derivatives: design, synthesis, and biological activity evaluation as potent dimeric DJ-1 inhibitors	14
Modified citrus pectin inhibits breast cancer development in mice by targeting tumor-associated macrophage survival and polarization in hypoxic microenvironment	14
Anemoside B4 inhibits enterovirus 71 propagation in mice through upregulating 14-3-3 expression and type I interferon responses	14
Repeated cocaine administration upregulates CB2 receptor expression in striatal medium-spiny neurons that express dopamine D1 receptors in mice	14
NFAT inhibitor 11R-VIVIT ameliorates mouse renal fibrosis after ischemia-reperfusion-induced acute kidney injury	14
Pinocembrin attenuates hemorrhagic transformation after delayed t-PA treatment in thromboembolic stroke rats by regulating endogenous metabolites	14