OOIR: Observatory of International Research

Papers

(The H4-Index of Acta Pharmacologica Sinica is 41. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-11-01 to 2024-11-01.)

Article	Citations
Natural products: potential treatments for cisplatin-induced nephrotoxicity	174
Endothelial dysfunction in COVID-19: an overview of evidence, biomarkers, mechanisms and potential therapies	171
Mitochondrial-derived damage-associated molecular patterns amplify neuroinflammation in neurodegenerative diseases	99
Deletion of TLR4 attenuates lipopolysaccharide-induced acute liver injury by inhibiting inflammation and apoptosis	88
Luteolin alleviates cognitive impairment in Alzheimer’s disease mouse model via inhibiting endoplasmic reticulum stress-dependent neuroinflammation	85
Baicalein ameliorates ulcerative colitis by improving intestinal epithelial barrier via AhR/IL-22 pathway in ILC3s	78
ATF3 contributes to brucine-triggered glioma cell ferroptosis via promotion of hydrogen peroxide and iron	76
Mutations in key driver genes of pancreatic cancer: molecularly targeted therapies and other clinical implications	72
Wogonin protects glomerular podocytes by targeting Bcl-2-mediated autophagy and apoptosis in diabetic kidney disease	72
Structure genomics of SARS-CoV-2 and its Omicron variant: drug design templates for COVID-19	68
The glycolytic process in endothelial cells and its implications	64
Mitochondrial aldehyde dehydrogenase (ALDH2) rescues cardiac contractile dysfunction in an APP/PS1 murine model of Alzheimer’s disease via inhibition of ACSL4-dependent ferroptosis	64
New therapeutics beyond amyloid-β and tau for the treatment of Alzheimer’s disease	62
NOD-like receptors in autoimmune diseases	61
DL-3-n-butylphthalide ameliorates diabetes-associated cognitive decline by enhancing PI3K/Akt signaling and suppressing oxidative stress	60
AlphaFold2 versus experimental structures: evaluation on G protein-coupled receptors	59
Pyroptosis and pyroptosis-inducing cancer drugs	59
Ferroptosis inhibitor liproxstatin-1 alleviates metabolic dysfunction-associated fatty liver disease in mice: potential involvement of PANoptosis	57
Blueberry-derived exosomes-like nanoparticles ameliorate nonalcoholic fatty liver disease by attenuating mitochondrial oxidative stress	56
Therapeutic potential of colchicine in cardiovascular medicine: a pharmacological review	55
Current advances in the use of exosomes, liposomes, and bioengineered hybrid nanovesicles in cancer detection and therapy	55
STING inhibitor ameliorates LPS-induced ALI by preventing vascular endothelial cells-mediated immune cells chemotaxis and adhesion	53
Bile acid and receptors: biology and drug discovery for nonalcoholic fatty liver disease	51
Metformin promotes microglial cells to facilitate myelin debris clearance and accelerate nerve repairment after spinal cord injury	49
Targeting HMGB1 for the treatment of sepsis and sepsis-induced organ injury	49

Salvianolic acid A prevented cerebrovascular endothelial injury caused by acute ischemic stroke through inhibiting the Src signaling pathway	49
Ginsenoside Rb1 alleviates diabetic kidney podocyte injury by inhibiting aldose reductase activity	48
Tu-San-Qi (Gynura japonica): the culprit behind pyrrolizidine alkaloid-induced liver injury in China	47
A multi-targeting drug design strategy for identifying potent anti-SARS-CoV-2 inhibitors	47
Catalpol improves impaired neurovascular unit in ischemic stroke rats via enhancing VEGF-PI3K/AKT and VEGF-MEK1/2/ERK1/2 signaling	47
Celastrol induces lipophagy via the LXRα/ABCA1 pathway in clear cell renal cell carcinoma	45
Tetrandrine alleviates silicosis by inhibiting canonical and non-canonical NLRP3 inflammasome activation in lung macrophages	44
Berberine alleviates visceral hypersensitivity in rats by altering gut microbiome and suppressing spinal microglial activation	44
Safety, tolerability, and pharmacokinetics of VV116, an oral nucleoside analog against SARS-CoV-2, in Chinese healthy subjects	43
Benzimidazoles induce concurrent apoptosis and pyroptosis of human glioblastoma cells via arresting cell cycle	43
Disulfiram-loaded lactoferrin nanoparticles for treating inflammatory diseases	43
Multi-compound and drug-combination pharmacokinetic research on Chinese herbal medicines	43
Discovery of potential small molecular SARS-CoV-2 entry blockers targeting the spike protein	42
Diterbutyl phthalate attenuates osteoarthritis in ACLT mice via suppressing ERK/c-fos/NFATc1 pathway, and subsequently inhibiting subchondral osteoclast fusion	42
Mesenchymal stem cells in fibrotic diseases—the two sides of the same coin	42
Ferroptosis in viral infection: the unexplored possibility	42