OOIR: Observatory of International Research

Papers

(The H4-Index of Frontiers in Genetics is 52. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-11-01 to 2025-11-01.)

Article	Citations
Transcriptome Sequencing Identifies PLAUR as an Important Player in Patients With Dermatomyositis-Associated Interstitial Lung Disease	270
Genomic Analysis of Visceral Fat Accumulation in Holstein Cows	188
Subject clustering by IF-PCA and several recent methods	154
RET splice site variants in medullary thyroid carcinoma	136
Fetal Congenital Heart Disease Caused by Compound Heterozygous Mutations in the DNAH9 Gene: A Case Report	136
Retraction: Cytokinin and abiotic stress tolerance -what has been accomplished and the way forward?	129
Whole genome sequencing and functional annotation of Fusarium oxysporum f. sp. lentis to unravel virulence and secondary metabolite biosynthesis gene clusters	120
Case report: Complete paternal isodisomy on chromosome 18 induces methylation changes in PARD6G-AS1 promotor in a case with arthrogryposis	118
BANSMDA: a computational model for predicting potential microbe-disease associations based on bilinear attention networks and sparse autoencoders	112
The Genetic and Clinical Outcomes in Fetuses With Isolated Fetal Growth Restriction: A Chinese Single-Center Retrospective Study	110
Erratum: Heterologous expression of Arabidopsis AtARA6 in soybean enhances salt tolerance	95
Editorial: Epigenetic mechanisms and epigenetic-based therapies in cardiometabolic and vascular disease	92
Bioinformatics revealed biomarkers for diagnosis in kidney stones	92
Identification and Validation of an Immune and Ferroptosis-Combined Index for Non–Small Cell Lung Cancer	92
Clinical characteristics and follow-up of complex arrhythmias associated with RYR2 gene mutations in children	79
Erratum: A self-repair history: compensatory effect of a de novo variant on the FANCA c.2778+83C>G splicing mutation	79
Consumer-oriented (patient and family) outcomes from nursing in genomics: a scoping review of the literature (2012–2022)	78
MiRNA-Seq reveals key MicroRNAs involved in fat metabolism of sheep liver	78
A Novel SPG7 Gene Pathogenic Variant in a Cypriot Family With Autosomal Recessive Spastic Ataxia	75
Genetically Determined Circulating Levels of Cytokines and the Risk of Rheumatoid Arthritis	72
Comprehensive Genetic Analysis of Tuberculosis and Identification of Candidate Biomarkers	72
Composition and Dynamics of H1N1 and H7N9 Influenza A Virus Quasispecies in a Co-infected Patient Analyzed by Single Molecule Sequencing Technology	71
A combined transcriptomics and proteomics approach reveals S100A4 as a potential biomarker for Graves’ orbitopathy	71
miR-224-5p and miR-545-5p Levels Relate to Exacerbations and Lung Function in a Pilot Study of X-Linked MicroRNA Expression in Cystic Fibrosis Monocytes	70
Imputation of Ancient Whole Genome Sus scrofa DNA Introduces Biases Toward Main Population Components in the Reference Panel	70

Comprehensive analysis of molecular features, prognostic values, and immune landscape association of m6A-regulated immune-related lncRNAs in smoking-associated lung squamous cell carcinoma	69
A transmembrane protein family gene signature for overall survival prediction in osteosarcoma	69
Genetically predicted 1091 blood metabolites and 309 metabolite ratios in relation to risk of type 2 diabetes: a Mendelian randomization study	66
Editorial: Multi-omics studies and applications in precision medicine	64
Identifying Functions of Proteins in Mice With Functional Embedding Features	63
Scaffolded and annotated nuclear and organelle genomes of the North American brown alga Saccharina latissima	63
MK2-mediated AKT/MYC signaling activation promotes epithelial-mesenchymal transition in lung adenocarcinoma	63
Profiling the Genome-Wide Landscape of Short Tandem Repeats by Long-Read Sequencing	62
COVID-19-specific transcriptomic signature detectable in blood across multiple cohorts	61
Comprehensive Analysis of the Transcriptome-Wide m6A Methylation in Mouse Pachytene Spermatocytes and Round Spermatids	60
Genomic and physiological mechanisms of high-altitude adaptation in Ethiopian highlanders: a comparative perspective	60
Investigating Doxorubicin’s mechanism of action in cervical cancer: a convergence of transcriptomic and metabolomic perspectives	60
Development and validation of a TRP-related gene signature for overall survival prediction in lung adenocarcinoma	59
Development of a risk model to predict prognosis in breast cancer based on cGAS-STING-related genes	58
Prioritizing potential circRNA biomarkers for bladder cancer and bladder urothelial cancer based on an ensemble model	58
Genetic and clinical landscape of Duchenne muscular dystrophy in Guatemala: insights from a national study	57
Construction of ceRNA network based on RNA-seq for identifying prognostic lncRNA biomarkers in Perthes disease	57
BCR::ABL1-negative myeloproliferative neoplasms in the era of next-generation sequencing	57
Transcriptome sequencing reveals novel molecular features of SLE severity	57
Editorial: Recent advances in nutrigenomics: Making strides towards precision nutrition	56
Spectrum of genetic disorders and gene variants in the United Arab Emirates national population: insights from the CTGA database	55
Gene set-based identification of two immune subtypes of diffuse large B cell lymphoma for guiding immune checkpoint blocking therapy	55
Potential immunomodulatory effects of the extract from Artemisia frigida Willd on loaches infested with Aeromonas hydrophila revealed by microRNA analysis	55
A Novel Age-Related Circular RNA Circ-ATXN2 Inhibits Proliferation, Promotes Cell Death and Adipogenesis in Rat Adipose Tissue-Derived Stromal Cells	54
Fusion Gene Detection Using Whole-Exome Sequencing Data in Cancer Patients	54
Identification of the ubiquitin–proteasome pathway domain by hyperparameter optimization based on a 2D convolutional neural network	54
Genome-wide identification of acyl-CoA binding proteins and possible functional prediction in legumes	52
CPIELA: Computational Prediction of Plant Protein–Protein Interactions by Ensemble Learning Approach From Protein Sequences and Evolutionary Information	52