OOIR: Observatory of International Research

Papers

(The H4-Index of Frontiers in Genetics is 49. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-11-01 to 2024-11-01.)

Article	Citations
Telomere Length as a Marker of Biological Age: State-of-the-Art, Open Issues, and Future Perspectives	219
State of the Field in Multi-Omics Research: From Computational Needs to Data Mining and Sharing	211
ggVennDiagram: An Intuitive, Easy-to-Use, and Highly Customizable R Package to Generate Venn Diagram	180
Nanoparticle Delivery of CRISPR/Cas9 for Genome Editing	164
Use ggbreak to Effectively Utilize Plotting Space to Deal With Large Datasets and Outliers	155
GNB3 c.825c>T polymorphism influences T-cell but not antibody response following vaccination with the mRNA-1273 vaccine	119
Graph Neural Networks and Their Current Applications in Bioinformatics	113
Heterosis and Hybrid Crop Breeding: A Multidisciplinary Review	107
DNA-PKcs: A Multi-Faceted Player in DNA Damage Response	98
Gene Size Matters: An Analysis of Gene Length in the Human Genome	92
Incomplete Penetrance and Variable Expressivity: From Clinical Studies to Population Cohorts	90
FTO – A Common Genetic Basis for Obesity and Cancer	85
A Comparison for Dimensionality Reduction Methods of Single-Cell RNA-seq Data	82
MSU-Net: Multi-Scale U-Net for 2D Medical Image Segmentation	82
Genomic Selection: A Tool for Accelerating the Efficiency of Molecular Breeding for Development of Climate-Resilient Crops	80
MeCP2: The Genetic Driver of Rett Syndrome Epigenetics	79
A novel anoikis-related gene signature predicts prognosis in patients with head and neck squamous cell carcinoma and reveals immune infiltration	77
Environmental Risk Factors for Schizophrenia and Bipolar Disorder and Their Relationship to Genetic Risk: Current Knowledge and Future Directions	75
Th2/Th1 Cytokine Imbalance Is Associated With Higher COVID-19 Risk Mortality	69
Spliceosomal snRNA Epitranscriptomics	66
Use of Multivariable Mendelian Randomization to Address Biases Due to Competing Risk Before Recruitment	66
From GWAS to Gene: Transcriptome-Wide Association Studies and Other Methods to Functionally Understand GWAS Discoveries	66
Explanation-Driven Deep Learning Model for Prediction of Brain Tumour Status Using MRI Image Data	66
Calculating Polygenic Risk Scores (PRS) in UK Biobank: A Practical Guide for Epidemiologists	65
Bacterial Response to Oxidative Stress and RNA Oxidation	65

Cuproptosis-Associated lncRNA Establishes New Prognostic Profile and Predicts Immunotherapy Response in Clear Cell Renal Cell Carcinoma	63
History and Domestication of Saccharomyces cerevisiae in Bread Baking	61
Human Aquaporins: Functional Diversity and Potential Roles in Infectious and Non-infectious Diseases	61
Unsupervised Multi-Omics Data Integration Methods: A Comprehensive Review	59
Adapting CRISPR/Cas9 System for Targeting Mitochondrial Genome	59
Intelligent Health Care: Applications of Deep Learning in Computational Medicine	58
Gene Environment Interactions in the Etiology of Neural Tube Defects	57
Metabolomics in the Diagnosis and Prognosis of COVID-19	57
Linking Oxidative Stress and DNA Damage to Changes in the Expression of Extracellular Matrix Components	56
Network Analysis and Transcriptome Profiling Identify Autophagic and Mitochondrial Dysfunctions in SARS-CoV-2 Infection	56
Machine Learning: A New Prospect in Multi-Omics Data Analysis of Cancer	56
Causal Inference for Genetic Obesity, Cardiometabolic Profile and COVID-19 Susceptibility: A Mendelian Randomization Study	56
Regular, Intense Exercise Training as a Healthy Aging Lifestyle Strategy: Preventing DNA Damage, Telomere Shortening and Adverse DNA Methylation Changes Over a Lifetime	53
COVID-19 and SARS-CoV-2 Variants: Current Challenges and Health Concern	53
Human Organoids for Predictive Toxicology Research and Drug Development	53
Mastermind: A Comprehensive Genomic Association Search Engine for Empirical Evidence Curation and Genetic Variant Interpretation	52
Transcriptomics of Biostimulation of Plants Under Abiotic Stress	51
Machine Learning Based Computational Gene Selection Models: A Survey, Performance Evaluation, Open Issues, and Future Research Directions	51
Epigenetic Regulation of Genomic Stability by Vitamin C	51
Applications of machine learning in metabolomics: Disease modeling and classification	51
Cuproptosis-Related lncRNAs are Biomarkers of Prognosis and Immune Microenvironment in Head and Neck Squamous Cell Carcinoma	50
Splicing in the Diagnosis of Rare Disease: Advances and Challenges	50
Pan-cancer analyses confirmed the cuproptosis-related gene FDX1 as an immunotherapy predictor and prognostic biomarker	50
Disease-Causing Mutations and Rearrangements in Long Non-coding RNA Gene Loci	49
Identification of Protein Subcellular Localization With Network and Functional Embeddings	49
Metagenomic Approaches to Analyze Antimicrobial Resistance: An Overview	49