OOIR: Observatory of International Research

Papers

(The H4-Index of Frontiers in Genetics is 52. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-12-01 to 2025-12-01.)

Article	Citations
Genomic Analysis of Visceral Fat Accumulation in Holstein Cows	195
Subject clustering by IF-PCA and several recent methods	168
RET splice site variants in medullary thyroid carcinoma	143
Retraction: Cytokinin and abiotic stress tolerance -what has been accomplished and the way forward?	138
Fetal Congenital Heart Disease Caused by Compound Heterozygous Mutations in the DNAH9 Gene: A Case Report	138
Whole genome sequencing and functional annotation of Fusarium oxysporum f. sp. lentis to unravel virulence and secondary metabolite biosynthesis gene clusters	124
Case report: Complete paternal isodisomy on chromosome 18 induces methylation changes in PARD6G-AS1 promotor in a case with arthrogryposis	120
The Genetic and Clinical Outcomes in Fetuses With Isolated Fetal Growth Restriction: A Chinese Single-Center Retrospective Study	117
Erratum: Heterologous expression of Arabidopsis AtARA6 in soybean enhances salt tolerance	114
Bioinformatics revealed biomarkers for diagnosis in kidney stones	96
Editorial: Epigenetic mechanisms and epigenetic-based therapies in cardiometabolic and vascular disease	96
Clinical characteristics and follow-up of complex arrhythmias associated with RYR2 gene mutations in children	95
Erratum: A self-repair history: compensatory effect of a de novo variant on the FANCA c.2778+83C>G splicing mutation	94
MiRNA-Seq reveals key MicroRNAs involved in fat metabolism of sheep liver	86
Consumer-oriented (patient and family) outcomes from nursing in genomics: a scoping review of the literature (2012–2022)	81
A Novel SPG7 Gene Pathogenic Variant in a Cypriot Family With Autosomal Recessive Spastic Ataxia	81
Amino Acid Metabolism-Related lncRNA Signature Predicts the Prognosis of Breast Cancer	77
Correction: Multi-omics integration uncovers key transcriptional regulators in triple-negative breast cancer spatial heterogeneity	77
Diagnostic efficiency of exome-based sequencing in pediatric patients with epilepsy	74
Evolutionary Genomics Reveals Multiple Functions of Arylalkylamine N-Acetyltransferase in Fish	74
Multiple Cases of Bacterial Sequence Erroneously Incorporated Into Publicly Available Chloroplast Genomes	74
Genetic Variation and the Distribution of Variant Types in the Horse	74
Identification of copy number variants contributing to hallux valgus	72
Hypoxia-Induced miR-378a-3p Inhibits Osteosarcoma Invasion and Epithelial-to-Mesenchymal Transition via BYSL Regulation	72
Identification of key genes for heart failure in dilated cardiomyopathy in different populations	71

Bioinformatics analysis reveals the landscape of immune cell infiltration and novel immune-related biomarkers in moyamoya disease	68
CircRNAs in osteoarthritis: research status and prospect	67
Proteome changes of dairy calves rumen epithelium from birth to postweaning	67
A combined transcriptomics and proteomics approach reveals S100A4 as a potential biomarker for Graves’ orbitopathy	66
Genomic and physiological mechanisms of high-altitude adaptation in Ethiopian highlanders: a comparative perspective	66
TRPV4 mRNA is elevated in the caudate nucleus with NPH but not in Alzheimer’s disease	66
Comprehensive analysis of molecular features, prognostic values, and immune landscape association of m6A-regulated immune-related lncRNAs in smoking-associated lung squamous cell carcinoma	64
Genetically predicted 1091 blood metabolites and 309 metabolite ratios in relation to risk of type 2 diabetes: a Mendelian randomization study	64
Scaffolded and annotated nuclear and organelle genomes of the North American brown alga Saccharina latissima	63
COVID-19-specific transcriptomic signature detectable in blood across multiple cohorts	62
Identifying Functions of Proteins in Mice With Functional Embedding Features	62
MK2-mediated AKT/MYC signaling activation promotes epithelial-mesenchymal transition in lung adenocarcinoma	62
Development and validation of a TRP-related gene signature for overall survival prediction in lung adenocarcinoma	60
Investigating Doxorubicin’s mechanism of action in cervical cancer: a convergence of transcriptomic and metabolomic perspectives	60
Comprehensive Analysis of the Transcriptome-Wide m6A Methylation in Mouse Pachytene Spermatocytes and Round Spermatids	60
Transcriptome sequencing reveals novel molecular features of SLE severity	58
Potential immunomodulatory effects of the extract from Artemisia frigida Willd on loaches infested with Aeromonas hydrophila revealed by microRNA analysis	57
BCR::ABL1-negative myeloproliferative neoplasms in the era of next-generation sequencing	57
Gene set-based identification of two immune subtypes of diffuse large B cell lymphoma for guiding immune checkpoint blocking therapy	57
Identification of the ubiquitin–proteasome pathway domain by hyperparameter optimization based on a 2D convolutional neural network	56
Fusion Gene Detection Using Whole-Exome Sequencing Data in Cancer Patients	56
CPIELA: Computational Prediction of Plant Protein–Protein Interactions by Ensemble Learning Approach From Protein Sequences and Evolutionary Information	56
Whole Genome Sequencing and Morphological Trait-Based Evaluation of UPOV Option 2 for DUS Testing in Rice	55
Geographical distribution of ALDH2 rs671 polymorphism in Chinese angina pectoris patients	55
Set of 15 SNP-SNP Markers for Detection of Unbalanced Degraded DNA Mixtures and Noninvasive Prenatal Paternity Testing	55
Panoramic analysis of the biological function and clinical value of SLC38A2 in human cancers: a study based on pan-cancer and single-cell analysis	53
The potential impact of GLS and PDHA1 on tumor immunity and immunotherapy response in LUSC	52
Identification of a novel locus C2 controlling canary yellow flesh color in watermelons	52
Moral judgment of genetic technologies: validation of the genetic technologies questionnaire in the German-speaking population	52
Systemic inflammatory regulators and preeclampsia: a two-sample bidirectional Mendelian randomization study	52
Genetic Loci Associated With COVID-19 Positivity and Hospitalization in White, Black, and Hispanic Veterans of the VA Million Veteran Program	52