OOIR: Observatory of International Research

Papers

(The H4-Index of Frontiers in Genetics is 52. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-03-01 to 2024-03-01.)

Article	Citations
From GWAS to Function: Using Functional Genomics to Identify the Mechanisms Underlying Complex Diseases	312
State of the Field in Multi-Omics Research: From Computational Needs to Data Mining and Sharing	167
Telomere Length as a Marker of Biological Age: State-of-the-Art, Open Issues, and Future Perspectives	167
DNA Methylation Biomarkers in Aging and Age-Related Diseases	145
Characterizing Extracellular Vesicles and Their Diverse RNA Contents	144
Chloroplot: An Online Program for the Versatile Plotting of Organelle Genomes	131
ggVennDiagram: An Intuitive, Easy-to-Use, and Highly Customizable R Package to Generate Venn Diagram	124
Nanoparticle Delivery of CRISPR/Cas9 for Genome Editing	123
Epigenetic Regulator miRNA Pattern Differences Among SARS-CoV, SARS-CoV-2, and SARS-CoV-2 World-Wide Isolates Delineated the Mystery Behind the Epic Pathogenicity and Distinct Clinical Characteristics	121
GNB3 c.825c>T polymorphism influences T-cell but not antibody response following vaccination with the mRNA-1273 vaccine	116
Gene Set Analysis: Challenges, Opportunities, and Future Research	115
Novel Immune-Related Gene Signature for Risk Stratification and Prognosis of Survival in Lower-Grade Glioma	114
Homoeologous Exchanges, Segmental Allopolyploidy, and Polyploid Genome Evolution	107
Use ggbreak to Effectively Utilize Plotting Space to Deal With Large Datasets and Outliers	105
The Genetic Basis and Nutritional Benefits of Pigmented Rice Grain	105
Reaching the End-Game for GWAS: Machine Learning Approaches for the Prioritization of Complex Disease Loci	97
Phthalate Exposure and Long-Term Epigenomic Consequences: A Review	97
Synergistic Enhancement of Cancer Therapy Using HDAC Inhibitors: Opportunity for Clinical Trials	92
Genomics of Evolutionary Novelty in Hybrids and Polyploids	89
Heavy Metal Stress-Associated Proteins in Rice and Arabidopsis: Genome-Wide Identification, Phylogenetics, Duplication, and Expression Profiles Analysis	89
Heterosis and Hybrid Crop Breeding: A Multidisciplinary Review	81
SCSA: A Cell Type Annotation Tool for Single-Cell RNA-seq Data	81
Analysis of Differentially Expressed Genes and Molecular Pathways in Familial Hypercholesterolemia Involved in Atherosclerosis: A Systematic and Bioinformatics Approach	80
Graph Neural Networks and Their Current Applications in Bioinformatics	79
Comparing the Performance of Microsatellites and RADseq in Population Genetic Studies: Analysis of Data for Pike (Esox lucius) and a Synthesis of Previous Studies	76

FTO – A Common Genetic Basis for Obesity and Cancer	72
DNA-PKcs: A Multi-Faceted Player in DNA Damage Response	71
Toxicological Effects of Cadmium on Mammalian Testis	71
Neutrophils, Crucial, or Harmful Immune Cells Involved in Coronavirus Infection: A Bioinformatics Study	70
Methodologies for Transcript Profiling Using Long-Read Technologies	68
Large-Scale Phenotyping of Livestock Welfare in Commercial Production Systems: A New Frontier in Animal Breeding	66
MeCP2: The Genetic Driver of Rett Syndrome Epigenetics	66
LncRNA NEAT1 Interacted With DNMT1 to Regulate Malignant Phenotype of Cancer Cell and Cytotoxic T Cell Infiltration via Epigenetic Inhibition of p53, cGAS, and STING in Lung Cancer	65
A Comparison for Dimensionality Reduction Methods of Single-Cell RNA-seq Data	65
A novel anoikis-related gene signature predicts prognosis in patients with head and neck squamous cell carcinoma and reveals immune infiltration	64
Gene Size Matters: An Analysis of Gene Length in the Human Genome	63
Incomplete Penetrance and Variable Expressivity: From Clinical Studies to Population Cohorts	63
The Molecular Chaperone CCT/TRiC: An Essential Component of Proteostasis and a Potential Modulator of Protein Aggregation	62
Use of Multivariable Mendelian Randomization to Address Biases Due to Competing Risk Before Recruitment	61
LncRNA Functions as a New Emerging Epigenetic Factor in Determining the Fate of Stem Cells	60
Genetic Association of ACE2 rs2285666 Polymorphism With COVID-19 Spatial Distribution in India	60
Th2/Th1 Cytokine Imbalance Is Associated With Higher COVID-19 Risk Mortality	57
Spliceosomal snRNA Epitranscriptomics	56
Weighted Gene Coexpression Network Analysis of Features That Control Cancer Stem Cells Reveals Prognostic Biomarkers in Lung Adenocarcinoma	56
A Review of Integrative Imputation for Multi-Omics Datasets	56
Environmental Risk Factors for Schizophrenia and Bipolar Disorder and Their Relationship to Genetic Risk: Current Knowledge and Future Directions	56
Causal Inference for Genetic Obesity, Cardiometabolic Profile and COVID-19 Susceptibility: A Mendelian Randomization Study	54
Human Aquaporins: Functional Diversity and Potential Roles in Infectious and Non-infectious Diseases	53
Cuproptosis-Associated lncRNA Establishes New Prognostic Profile and Predicts Immunotherapy Response in Clear Cell Renal Cell Carcinoma	53
Advances in RNA 3D Structure Modeling Using Experimental Data	53
MSU-Net: Multi-Scale U-Net for 2D Medical Image Segmentation	53
From GWAS to Gene: Transcriptome-Wide Association Studies and Other Methods to Functionally Understand GWAS Discoveries	52
A Literature Review of Gene Function Prediction by Modeling Gene Ontology	52
Management of Genetic Diversity in the Era of Genomics	52
Adapting CRISPR/Cas9 System for Targeting Mitochondrial Genome	52
The Role of the Gut Microbiome in Energy Balance With a Focus on the Gut-Adipose Tissue Axis	52