OOIR: Observatory of International Research

Papers

(The H4-Index of Frontiers in Genetics is 53. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-05-01 to 2026-05-01.)

Article	Citations
Subject clustering by IF-PCA and several recent methods	236
RET splice site variants in medullary thyroid carcinoma	163
Whole genome sequencing and functional annotation of Fusarium oxysporum f. sp. lentis to unravel virulence and secondary metabolite biosynthesis gene clusters	153
Editorial: Epigenetic mechanisms and epigenetic-based therapies in cardiometabolic and vascular disease	120
Case report: Complete paternal isodisomy on chromosome 18 induces methylation changes in PARD6G-AS1 promotor in a case with arthrogryposis	120
Geographical distribution of ALDH2 rs671 polymorphism in Chinese angina pectoris patients	111
Panoramic analysis of the biological function and clinical value of SLC38A2 in human cancers: a study based on pan-cancer and single-cell analysis	105
Moral judgment of genetic technologies: validation of the genetic technologies questionnaire in the German-speaking population	98
The potential impact of GLS and PDHA1 on tumor immunity and immunotherapy response in LUSC	97
Identification of a novel locus C2 controlling canary yellow flesh color in watermelons	96
Editorial: Forensic investigative genetic genealogy and fine-scale structure of human populations	94
Editorial: New insights in cellular and molecular biology of cancer stem cells	90
Editorial: High-throughput sequencing-based investigation of chronic disease markers and mechanisms, volume II	89
Association between arthropathies and postpartum hemorrhage: a bidirectional Mendelian randomization study	88
Regulatory role of N6-Methyladenosine on skeletal muscle development in Hu sheep	86
Metabolic reprogramming and prognostic modeling in pancreatic cancer: insights from WGCNA	85
Editorial: Genetic and epigenetic aspects of non-coding RNAs in physiology and disease	85
A de novo TNNI3K variant aggravates the pathogenicity of DMD-associated early-onset cardiomyopathy: a case report	82
Utilization of hypoxia-derived gene signatures to predict clinical outcomes and immune checkpoint blockade therapy responses in prostate cancer	82
Editorial: Genetics of reproduction for livestock species	81
Editorial: Computational methods to analyze RNA data for human diseases	78
A comprehensive splicing characterization of COL4A5 mutations and prognostic significance in a single cohort with X-linked alport syndrome	77
Editorial: Prediction and explanation in biomedicine using network-based approaches	77
Early-Life Exposure of Pigs to Topsoil Alters miRNA and mRNA Expression in Peripheral Blood Mononuclear Cells	76
FGF/FGFR-related lncRNAs based classification predicts prognosis and guides therapy in gastric cancer	75

Skin-specific transgenic overexpression of ovine β-catenin in mice	75
Development and validation of a chromatin regulator prognostic signature in colon adenocarcinoma	74
Loss-of-function variant in the LRR domain of SLITRK2 implicated in a neurodevelopmental disorder	73
Mutational signatures representative transcriptomic perturbations in hepatocellular carcinoma	72
Exploration and identification of six novel ferroptosis-related hub genes as potential gene signatures for peripheral nerve injury	71
Two machine learning-derived nomogram for predicting the occurrence and severity of acute graft-versus-host disease: a retrospective study based on serum biomarkers	71
Case Report: Prenatal Identification of a De Novo Mosaic Neocentric Marker Resulting in 13q31.1→qter Tetrasomy in a Mildly Affected Girl	70
Identification of discriminant features from stationary pattern of nucleotide bases and their application to essential gene classification	68
Capturing heart valve development with Gene Ontology	68
Novel causative RYR2 indel variant with exon and intron involvement inducing exon 13 skipping in a family exhibiting catecholaminergic polymorphic ventricular tachycardia	67
MFRP variations cause nanophthalmos in five Chinese families with distinct phenotypic diversity	67
Refined expression quantitative trait locus analysis on adenocarcinoma at the gastroesophageal junction reveals susceptibility and prognostic markers	66
Characterization of novel human endogenous retrovirus structures on chromosomes 6 and 7	65
Multi-task learning for predicting SARS-CoV-2 antibody escape	65
Neoepitope load, T cell signatures and PD-L2 as combined biomarker strategy for response to checkpoint inhibition immunotherapy	65
Construction of a prognostic model related to copper dependence in breast cancer by single-cell sequencing analysis	62
Perthes Disease in a Child With Osteogenesis Imperfecta From a Rare Genetic Variant: A Case Report	60
Case Report: Prenatal Diagnosis of Postaxial Polydactyly With Bi-Allelic Variants in Smoothened (SMO)	60
Editorial: The ethics and challenges of studying the genetics of marginalized populations	60
An immune infiltration-related long non-coding RNAs signature predicts prognosis for hepatocellular carcinoma	58
Mitochondrial DNA heteroplasmy analysis in keratoconus patients from China	58
Using multi-tissue transcriptome-wide association study to identify candidate susceptibility genes for respiratory infectious diseases	57
Genetic Structure of the Endangered Coral Cladocora caespitosa Matches the Main Bioregions of the Mediterranean Sea	56
Construction of ceRNA network based on RNA-seq for identifying prognostic lncRNA biomarkers in Perthes disease	56
Case Report: Whole-Exome Sequencing-Based Copy Number Variation Analysis Identified a Novel DRC1 Homozygous Exon Deletion in a Patient With Primary Ciliary Dyskinesia	55
Systemic inflammatory regulators and preeclampsia: a two-sample bidirectional Mendelian randomization study	55
KLF4 loss in hepatocellular carcinoma: Improving prognostic prediction and correlating immune infiltrates	54
From genetic data to kinship clarity: employing machine learning for detecting incestuous relations	54
Genetic basis of phenotypic diversity in C. stenophylla: a stepping stone for climate-adapted coffee cultivar development	53