OOIR: Observatory of International Research

Papers

(The H4-Index of Frontiers in Genetics is 50. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-05-01 to 2025-05-01.)

Article	Citations
Regulatory role of N6-Methyladenosine on skeletal muscle development in Hu sheep	262
Editorial: Forensic investigative genetic genealogy and fine-scale structure of human populations	214
Fetal Congenital Heart Disease Caused by Compound Heterozygous Mutations in the DNAH9 Gene: A Case Report	201
Editorial: Genetic and epigenetic aspects of non-coding RNAs in physiology and disease	169
Development of a risk model to predict prognosis in breast cancer based on cGAS-STING-related genes	141
Utilization of hypoxia-derived gene signatures to predict clinical outcomes and immune checkpoint blockade therapy responses in prostate cancer	120
Mitochondrial DNA heteroplasmy analysis in keratoconus patients from China	104
Case report: Complete paternal isodisomy on chromosome 18 induces methylation changes in PARD6G-AS1 promotor in a case with arthrogryposis	104
Editorial: The ethics and challenges of studying the genetics of marginalized populations	101
Editorial: Computational methods to analyze RNA data for human diseases	94
Genetics and marker-assisted breeding for sex expression in cucumber	94
A syndrome differentiation model of TCM based on multi-label deep forest using biomedical text mining	92
Identification of discriminant features from stationary pattern of nucleotide bases and their application to essential gene classification	90
Prediction of Alternative Drug-Induced Liver Injury Classifications Using Molecular Descriptors, Gene Expression Perturbation, and Toxicology Reports	88
Epigenome-wide DNA methylation profiling in comparison between pathological and physiological hypertrophy of human cardiomyocytes	87
Case Report: CNNM2 Mutations Cause Damaged Brain Development and Intractable Epilepsy in a Patient Without Hypomagnesemia	86
Development and validation of a TRP-related gene signature for overall survival prediction in lung adenocarcinoma	83
Editorial: Epigenetic mechanisms and epigenetic-based therapies in cardiometabolic and vascular disease	74
Loss-of-function variant in the LRR domain of SLITRK2 implicated in a neurodevelopmental disorder	71
Perthes Disease in a Child With Osteogenesis Imperfecta From a Rare Genetic Variant: A Case Report	70
Editorial: Genetics of reproduction for livestock species	69
Case Report: Prenatal Diagnosis of Postaxial Polydactyly With Bi-Allelic Variants in Smoothened (SMO)	68
Case Report: Prenatal Identification of a De Novo Mosaic Neocentric Marker Resulting in 13q31.1→qter Tetrasomy in a Mildly Affected Girl	68
Genome Size Estimation and Full-Length Transcriptome of Sphingonotus tsinlingensis: Genetic Background of a Drought-Adapted Grasshopper	67
Case Report: Whole-Exome Sequencing-Based Copy Number Variation Analysis Identified a Novel DRC1 Homozygous Exon Deletion in a Patient With Primary Ciliary Dyskinesia	67

Development and validation of a chromatin regulator prognostic signature in colon adenocarcinoma	66
Genetic Variation and the Distribution of Variant Types in the Horse	63
Unveiling the genetic basis of Fusarium wilt resistance in chickpea using GWAS analysis and characterization of candidate genes	61
Associations Between Sleep Quality and Health Span: A Prospective Cohort Study Based on 328,850 UK Biobank Participants	61
Genetically predicted 1091 blood metabolites and 309 metabolite ratios in relation to risk of type 2 diabetes: a Mendelian randomization study	61
Genome-Wide Identification of mRNAs, lncRNAs, and Proteins, and Their Relationship With Sheep Fecundity	60
Footprints in the Sand: Deep Taxonomic Comparisons in Vertebrate Genomics to Unveil the Genetic Programs of Human Longevity	60
Diaphragmatic Hernia as a Prenatal Feature of Glycosylphosphatidylinositol Biosynthesis Defects and the Overlap With Fryns Syndrome – Literature Review	57
HNF1β, LHX1, and GGNBP2 deletion contributed to kidney and reproductive dysfunction in 17q12 deletion syndrome: evidence from a case report	57
MiRNA-Seq reveals key MicroRNAs involved in fat metabolism of sheep liver	57
Gene set-based identification of two immune subtypes of diffuse large B cell lymphoma for guiding immune checkpoint blocking therapy	57
The association of metabolic syndrome with telomere length as a marker of cellular aging: a systematic review and meta-analysis	56
Conduction and validation of a novel mitotic spindle assembly related signature in hepatocellular carcinoma: prognostic prediction, tumor immune microenvironment and drug susceptibility	56
Non-oral manifestations in adults with a clinical and molecularly confirmed diagnosis of periodontal Ehlers-Danlos syndrome	55
EMILIN2 is associated with prognosis and immunotherapy in clear cell renal cell carcinoma	54
Subject clustering by IF-PCA and several recent methods	53
Functional analysis of RRAS2 pathogenic variants with a Noonan-like phenotype	53
Copy Number Variations Analysis Identifies QPRT as a Candidate Gene Associated With Susceptibility for Solitary Functioning Kidney	53
Editorial: New insights in cellular and molecular biology of cancer stem cells	53
Hereditary orotic aciduria identified by newborn screening	52
Mutational signatures representative transcriptomic perturbations in hepatocellular carcinoma	51
Bioinformatics revealed biomarkers for diagnosis in kidney stones	51
Genetic tests as the strongest motivator of cooperation between participants and biobanks–Findings from cross-sectional study	51
Case Report: Report of Two Cases of Interstitial Lung Disease Caused by Novel Compound Heterozygous Variants in the ABCA3 Gene	50
iRGvalid: A Robust in silico Method for Optimal Reference Gene Validation	50