Frontiers in Immunology

Papers
(The H4-Index of Frontiers in Immunology is 114. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-11-01 to 2024-11-01.)
ArticleCitations
Tumor-Associated Macrophages in Tumor Immunity993
IOBR: Multi-Omics Immuno-Oncology Biological Research to Decode Tumor Microenvironment and Signatures507
Cancer Immune Evasion Through Loss of MHC Class I Antigen Presentation495
The Gut-Brain Axis: How Microbiota and Host Inflammasome Influence Brain Physiology and Pathology409
Anti-Inflammatory and Immunomodulatory Effects of Probiotics in Gut Inflammation: A Door to the Body371
Mucosal Immunity in COVID-19: A Neglected but Critical Aspect of SARS-CoV-2 Infection313
Toll-Like Receptor Signaling and Its Role in Cell-Mediated Immunity304
The Intestinal Microbiota and Colorectal Cancer300
NF-κB: At the Borders of Autoimmunity and Inflammation292
Impact of Bacterial Metabolites on Gut Barrier Function and Host Immunity: A Focus on Bacterial Metabolism and Its Relevance for Intestinal Inflammation240
Macrophage Polarization and Its Role in Liver Disease237
Interleukin-6 Is a Biomarker for the Development of Fatal Severe Acute Respiratory Syndrome Coronavirus 2 Pneumonia232
Aspects of the Tumor Microenvironment Involved in Immune Resistance and Drug Resistance232
Role of Metabolic Endotoxemia in Systemic Inflammation and Potential Interventions228
Macrophages: The Good, the Bad, and the Gluttony226
SARS-CoV-2 Accessory Proteins in Viral Pathogenesis: Knowns and Unknowns226
Reaction of Human Monoclonal Antibodies to SARS-CoV-2 Proteins With Tissue Antigens: Implications for Autoimmune Diseases226
Neutrophils in COVID-19218
The Role of Inflammation in Diabetic Retinopathy217
CD8+ T Cell Exhaustion in Cancer216
The Role of M1/M2 Macrophage Polarization in Rheumatoid Arthritis Synovitis206
Regulation of PD-L1 Expression by NF-κB in Cancer204
SARS-CoV-2 Variants, Vaccines, and Host Immunity201
Epstein-Barr Virus and Systemic Autoimmune Diseases196
IL-1β and the Intestinal Epithelial Tight Junction Barrier193
Humoral Responses and Serological Assays in SARS-CoV-2 Infections192
Role of Vascular Smooth Muscle Cell Plasticity and Interactions in Vessel Wall Inflammation180
Role of the IL-23/IL-17 Pathway in Rheumatic Diseases: An Overview180
Immune Cells in the BBB Disruption After Acute Ischemic Stroke: Targets for Immune Therapy?179
Reactive Oxygen Species in Macrophages: Sources and Targets179
Monocytes and Macrophages in COVID-19176
Exhausted CD8+T Cells in the Tumor Immune Microenvironment: New Pathways to Therapy175
ROS-triggered endothelial cell death mechanisms: Focus on pyroptosis, parthanatos, and ferroptosis173
The role of PD-1/PD-L1 and application of immune-checkpoint inhibitors in human cancers171
The IL-23/IL-17 Pathway in Inflammatory Skin Diseases: From Bench to Bedside170
Unraveling the Mystery Surrounding Post-Acute Sequelae of COVID-19170
Acute Transverse Myelitis (ATM):Clinical Review of 43 Patients With COVID-19-Associated ATM and 3 Post-Vaccination ATM Serious Adverse Events With the ChAdOx1 nCoV-19 Vaccine (AZD1222)169
Immunosuppressive Mechanisms of Regulatory B Cells168
The Roles of Inflammation in Keloid and Hypertrophic Scars164
SARS-CoV-2 Vaccines Based on the Spike Glycoprotein and Implications of New Viral Variants164
Partners in Leaky Gut Syndrome: Intestinal Dysbiosis and Autoimmunity163
Efficacy, Immunogenicity and Safety of COVID-19 Vaccines: A Systematic Review and Meta-Analysis162
CD38: An Immunomodulatory Molecule in Inflammation and Autoimmunity162
Increased sCD163 and sCD14 Plasmatic Levels and Depletion of Peripheral Blood Pro-Inflammatory Monocytes, Myeloid and Plasmacytoid Dendritic Cells in Patients With Severe COVID-19 Pneumonia162
Regulation of SIRT1 and Its Roles in Inflammation161
The Role of Macrophages in Staphylococcus aureus Infection161
Differentiation and Regulation of TH Cells: A Balancing Act for Cancer Immunotherapy159
Causal Relationship Between Gut Microbiota and Autoimmune Diseases: A Two-Sample Mendelian Randomization Study158
Microglia and Inflammatory Responses in Diabetic Retinopathy158
Janus Kinase Inhibition Ameliorates Ischemic Stroke Injury and Neuroinflammation Through Reducing NLRP3 Inflammasome Activation via JAK2/STAT3 Pathway Inhibition156
The Global Epidemic of the SARS-CoV-2 Delta Variant, Key Spike Mutations and Immune Escape156
Augmenting Anticancer Immunity Through Combined Targeting of Angiogenic and PD-1/PD-L1 Pathways: Challenges and Opportunities155
NF-κB Pathway as a Potential Target for Treatment of Critical Stage COVID-19 Patients155
Adjuvants for Coronavirus Vaccines155
Maternal-Fetal Inflammation in the Placenta and the Developmental Origins of Health and Disease154
Cells of the Immune System in Cardiac Remodeling: Main Players in Resolution of Inflammation and Repair After Myocardial Infarction151
Different Innate and Adaptive Immune Responses to SARS-CoV-2 Infection of Asymptomatic, Mild, and Severe Cases151
Obesity, Inflammation, and Immune System in Osteoarthritis150
Tumor Necrosis Factor Receptors: Pleiotropic Signaling Complexes and Their Differential Effects149
Gallic Acid Alleviates Gouty Arthritis by Inhibiting NLRP3 Inflammasome Activation and Pyroptosis Through Enhancing Nrf2 Signaling149
Association of Inflammatory Cytokines With Non-Alcoholic Fatty Liver Disease148
Immunotherapy in Lung Cancer: Current Landscape and Future Directions148
Genetics Insight for COVID-19 Susceptibility and Severity: A Review148
Microbiota Modulation of the Gut-Lung Axis in COVID-19148
Risk Factors and Biomarkers for Immune-Related Adverse Events: A Practical Guide to Identifying High-Risk Patients and Rechallenging Immune Checkpoint Inhibitors147
TERT—Regulation and Roles in Cancer Formation147
Omicron: A Heavily Mutated SARS-CoV-2 Variant Exhibits Stronger Binding to ACE2 and Potently Escapes Approved COVID-19 Therapeutic Antibodies146
Persistence of SARS CoV-2 S1 Protein in CD16+ Monocytes in Post-Acute Sequelae of COVID-19 (PASC) up to 15 Months Post-Infection146
COVID-19: Coronavirus Vaccine Development Updates145
Cuproptosis-Related Risk Score Predicts Prognosis and Characterizes the Tumor Microenvironment in Hepatocellular Carcinoma145
Sexual Dimorphism in Innate Immunity: The Role of Sex Hormones and Epigenetics145
Kaempferol Alleviates Murine Experimental Colitis by Restoring Gut Microbiota and Inhibiting the LPS-TLR4-NF-κB Axis143
Role of Human Milk Bioactives on Infants' Gut and Immune Health143
Therapeutic application of quercetin in aging-related diseases: SIRT1 as a potential mechanism143
Modulation of Immune Responses by Particle Size and Shape142
Bispecific Antibodies: From Research to Clinical Application140
The Role of Natural Killer Cells in Autoimmune Diseases140
Hepatocellular Carcinoma Immune Landscape and the Potential of Immunotherapies139
A Bibliometric Analysis of Pyroptosis From 2001 to 2021137
Sex Differences in Immunity to Viral Infections137
Digital Twins for Multiple Sclerosis137
Lactobacillus spp. for Gastrointestinal Health: Current and Future Perspectives136
Cytokines in CAR T Cell–Associated Neurotoxicity133
Immunomodulatory and Regenerative Effects of Mesenchymal Stem Cells and Extracellular Vesicles: Therapeutic Outlook for Inflammatory and Degenerative Diseases133
C-Reactive Protein and Cancer—Diagnostic and Therapeutic Insights132
Neoantigen: A New Breakthrough in Tumor Immunotherapy131
Dermatomyositis With Anti-MDA5 Antibodies: Bioclinical Features, Pathogenesis and Emerging Therapies130
Neutrophil Extracellular Traps Promote T Cell Exhaustion in the Tumor Microenvironment129
Effects of Mesenchymal Stem Cell-Derived Exosomes on Autoimmune Diseases127
Controlling Cytokine Storm Is Vital in COVID-19126
Immunogenic Cell Death Induction by Ionizing Radiation126
Gut Microbiota Interact With the Brain Through Systemic Chronic Inflammation: Implications on Neuroinflammation, Neurodegeneration, and Aging126
Immunogenicity and toxicity of AAV gene therapy126
Roles of Macrophage Polarization and Macrophage-Derived miRNAs in Pulmonary Fibrosis125
Interleukins and Ischemic Stroke125
Immune-Based Prediction of COVID-19 Severity and Chronicity Decoded Using Machine Learning124
Causal Effects of Gut Microbiome on Systemic Lupus Erythematosus: A Two-Sample Mendelian Randomization Study123
A Comprehensive Review of Viral Characteristics, Transmission, Pathophysiology, Immune Response, and Management of SARS-CoV-2 and COVID-19 as a Basis for Controlling the Pandemic123
Immunotherapy: Reshape the Tumor Immune Microenvironment123
B7-H3/CD276: An Emerging Cancer Immunotherapy122
Diversity of Macrophages in Lung Homeostasis and Diseases122
Exosome-Based Vaccines: History, Current State, and Clinical Trials120
The Role of Microbiota in Infant Health: From Early Life to Adulthood120
Potential Implications of Quercetin in Autoimmune Diseases120
TIGIT, the Next Step Towards Successful Combination Immune Checkpoint Therapy in Cancer119
Type I Interferon (IFN)-Regulated Activation of Canonical and Non-Canonical Signaling Pathways119
IgE and IgG Antibodies as Regulators of Mast Cell and Basophil Functions in Food Allergy119
Immunogenicity Risk Profile of Nanobodies118
Programmed Cell Death Tunes Tumor Immunity116
Importance of Type I and III Interferons at Respiratory and Intestinal Barrier Surfaces116
Prevalence of Hyperuricemia Among Chinese Adults: Findings From Two Nationally Representative Cross-Sectional Surveys in 2015–16 and 2018–19115
The Macrophage-Osteoclast Axis in Osteoimmunity and Osteo-Related Diseases115
Akkermansia muciniphila and Gut Immune System: A Good Friendship That Attenuates Inflammatory Bowel Disease, Obesity, and Diabetes115
Tumor-Associated Macrophages Regulate PD-1/PD-L1 Immunosuppression115
Polarized Macrophages in Periodontitis: Characteristics, Function, and Molecular Signaling114
Neutrophils in the Pathogenesis of Rheumatoid Arthritis and Systemic Lupus Erythematosus: Same Foe Different M.O.114
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