Frontiers in Pharmacology

Article	Citations
Scientific and Artful Voices of Resilience	1316
A Systematic Review and Meta-Analysis of the Efficacy and Safety of Xinbao Pill in Chronic Heart Failure	430
A Retrospective Cohort Study: Safety and Effectiveness of Elbasvir/Grazoprevir ± Ribavirin Compared With Ombitasvir/Paritaprevir/Ritonavir/Dasabuvir ± Ribavirin in Patients With Chronic Hepatitis C Ge	409
Editorial: Leukocyte biology and muscle pathology: Leukocytes as potential targets to control muscle inflammation, mass, and pain	365
Editorial: Women in neuropharmacology: 2021	334
Podocytes are likely the therapeutic target of IgA nephropathy with isolated hematuria: Evidence from repeat renal biopsy	314
Editorial: Model-informed decision making in the preclinical stages of pharmaceutical research and development	301
Editorial: Women in obstetric and pediatric pharmacology: 2021	246
The impact of aspirin exposure prior to intensive care unit admission on the outcomes for patients with sepsis-associated acute respiratory failure	215
Editorial: Emerging researchers in frontiers in pharmacology: obstetric and pediatric pharmacology 2022	204
Editorial: Ferroptosis as a novel therapeutic target for inflammation-related diseases	193
Medication-Related Readmissions: Documentation of the Medication Involved and Communication in the Care Continuum	193
Comparative antiseizure medications of adjunctive treatment for children with drug-resistant focal-onset seizures: A systematic review and network meta-analysis	181
When we shouldn’t borrow information from an existing network of trials for planning a new trial	165
Attenuation of intestinal ischemia-reperfusion-injury by anesthetics: a potentially protective effect of anesthetic management in experimental studies	162
Anticancer effects of OSW-1 on glioma cells via regulation of the PI3K/AKT signal pathway: A network pharmacology approach and experimental validation in vitro and in vivo	155
Trends in the Research Into Immune Checkpoint Blockade by Anti-PD1/PDL1 Antibodies in Cancer Immunotherapy: A Bibliometric Study	150
Medication use in Italian nursing homes: preliminary results from the national monitoring system	137
PAnno: A pharmacogenomics annotation tool for clinical genomic testing	134
Protective effect and mechanism of Qingfei Paidu decoction on myocardial damage mediated by influenza viruses	133
Evaluation of variable new antigen receptors (vNARs) as a novel cathepsin S (CTSS) targeting strategy	131
Does preterm birth increase the initiation of antidepressant use during the postpartum? A population-based investigation	130
Osimertinib in the treatment of resected EGFR-mutated non-small cell lung cancer: a cost-effectiveness analysis in the United States	129
Editorial: Non-coding RNA and Wnt/β-Catenin Signaling Pathway in Human Cancer	127
Dapagliflozin versus sacubitril–valsartan for heart failure with mildly reduced or preserved ejection fraction	124

Aqueous extract of Amydrium sinense (Engl.) H. Li alleviates hepatic fibrosis by suppressing hepatic stellate cell activation through inhibiting Stat3 signaling	124
Emerging Significance of Ginsenosides as Potentially Reversal Agents of Chemoresistance in Cancer Therapy	123
Herbal Medicine Compared to Placebo for Chronic Obstructive Pulmonary Disease: A Systematic Review and Meta-Analysis	120
The self-medication behaviors of residents and the factors related to the consideration of drug efficacy and safety—A cross-sectional study in China	120
Exploring the mechanism of action of licorice in the treatment of COVID-19 through bioinformatics analysis and molecular dynamics simulation	111
Editorial: Translational Research and Drug Repurposing for Non-Communicable Diseases (NCDs)	110
Arecoline Enhances Phosphodiesterase 4A Activity to Promote Transforming Growth Factor-β-Induced Buccal Mucosal Fibroblast Activation via cAMP-Epac1 Signaling Pathway	110
Targeting the Interaction of GABAB Receptors With CHOP After an Ischemic Insult Restores Receptor Expression and Inhibits Progressive Neuronal Death	108
Developmental adverse effects of trace amounts of lead: Evaluation using zebrafish model	108
No ambiguity: Chemosensory-based ayurvedic classification of medicinal plants can be fingerprinted using E-tongue coupled with multivariate statistical analysis	107
Effect of Fu Zheng Jie Du Formula on outcomes in patients with severe pneumonia receiving prone ventilation: a retrospective cohort study	106
Anti-TNFα in inflammatory bowel disease: from originators to biosimilars	106
Study on the Chemical Constituents and Anti-Migraine Activity of Supercritical CO2 Extracts of Zanthoxylum schinifolium	105
Editorial: State of the science of pharmacogenomics implementation in healthcare systems and communities	103
Intestinal mucosal barrier: a potential target for traditional Chinese medicine in the treatment of cardiovascular diseases	102
Supportive care of female hormones in brain health: what and how?	100
Ruthenium complexes show potent inhibition of AKR1C1, AKR1C2, and AKR1C3 enzymes and anti-proliferative action against chemoresistant ovarian cancer cell line	99
Optimal concentration of ropivacaine for brachial plexus blocks in adult patients undergoing upper limb surgeries: a systematic review and meta-analysis	99
Do Genetic Polymorphisms Affect Fetal Hemoglobin (HbF) Levels in Patients With Sickle Cell Anemia Treated With Hydroxyurea? A Systematic Review and Pathway Analysis	99
Endoplasmic Reticulum Adaptation and Autophagic Competence Shape Response to Fluid Shear Stress in T24 Bladder Cancer Cells	98
Molecular Action of Hydroxytyrosol in Attenuation of Intimal Hyperplasia: A Scoping Review	97
1,25-Dihydroxyvitamin D inhibits hepatic diacyglycerol accumulation and ameliorates metabolic dysfunction in polycystic ovary syndrome rat models	94
Sivelestat Alleviates Atherosclerosis by Improving Intestinal Barrier Function and Reducing Endotoxemia	92
Efficacy and safety of targeted therapeutics for patients with radioiodine-refractory differentiated thyroid cancer: Systematic review and network meta-analysis	92
In-depth LC-MS and in-vitro studies of a triterpenoid saponin capilliposide-A metabolism modulation in gut microbiota of mice	90
Prevalence of Chronic Polypharmacy in Community-Dwelling Elderly People in Poland: Analysis of National Real-World Database Helps to Identify High Risk Group	90
Herb-Drug Interaction Between Xiyanping Injection and Lopinavir/Ritonavir, Two Agents Used in COVID-19 Pharmacotherapy	89
Elevated Serum Uric Acid is Associated With Poor Survival in Advanced HCC Patients and Febuxostat Improves Prognosis in HCC Rats	87
Osteoprotective Effects in Postmenopausal Osteoporosis Rat Model: Oral Tocotrienol vs. Intraosseous Injection of Tocotrienol-Poly Lactic-Co-Glycolic Acid Combination	87
Sea Buckthorn Proanthocyanidins are the Protective Agent of Mitochondrial Function in Macrophages Under Oxidative Stress	85
Current situation and future development of the biopharmaceutical industry in China: A mixed-method study	85
Chronic Administration of COVID-19 Drugs Fluvoxamine and Lopinavir Shortens Action Potential Duration by Inhibiting the Human Ether‐à‐go‐go–Related Gene and Cav1.2	85
Trends in orphan drug use and spending among children and adolescents during 2010–2020 in Korea	82
Chinese herbal medicine xuebijing injection for acute pancreatitis: An overview of systematic reviews	82
Zuogui Wan ameliorates high glucose-induced podocyte apoptosis and improves diabetic nephropathy in db/db mice	82
Editorial: The Potential of Machine-learning in Pharmacogenetics, Pharmacogenomics and Pharmacoepidemiology: Volume II	80
Efficacy of Xinbao pill on chronic heart failure: Study protocol of a multicenter, randomized, double-blind, placebo-controlled trial	80
Pre-clinical toxicity assessment of Artemisia absinthium extract-loaded polymeric nanoparticles associated with their oral administration	79
Identification of potential quality markers of Zishen Yutai pill based on spectrum–effect relationship analysis	78
Therapeutic Targeting of Endosome and Mitochondrial Reactive Oxygen Species Protects Mice From Influenza Virus Morbidity	77
Integrative population pharmacokinetic/pharmacodynamic analysis of nemonoxacin capsule in Chinese patients with community-acquired pneumonia	76
Factors determining the sensitivity to proteasome inhibitors of multiple myeloma cells	76
Effects of the Full Coverage Policy of Essential Medicines on Inequality in Medication Adherence: A Longitudinal Study in Taizhou, China	75
Ten Rules for Conducting Retrospective Pharmacoepidemiological Analyses: Example COVID-19 Study	75
Shumian Capsule Improves the Sleep Disorder and Mental Symptoms Through Melatonin Receptors in Sleep-Deprived Mice	74
Beta-blocker exposure and survival outcomes in patients with advanced pancreatic ductal adenocarcinoma: a retrospective cohort study (BETAPANC)	73
Relevance of Peptide Homeostasis in Metabolic Retinal Degenerative Disorders: Curative Potential in Genetically Modified Mice	73
Editorial: Phytochemicals targeting autophagy in treatment of bacterial infection and malignancies	73
Safety and effectiveness of fondaparinux as a postpartum thromboprophylaxis during puerperium among muslim women: A single centre prospective study	72
Comparative study of the effects of the three kinds of Kampo-hozai: Ninjinyoeito, Hochuekkito, and Juzentaihoto on anxious and low sociability behavior using NPY-knockout zebrafish	72

Editorial: Pharmacology of autoimmune and neuroinflammatory disease from a preclinical and clinical perspective	71
Yisaipu® Provide AS Patients With an Economical Therapeutic Option While Original Biologicals are More Advantageous in the COVID-19 Epidemic Situation	70
Liu Shen Capsule Alters Airway Microbiota Composition and Metabolite Profiles in Healthy Humans	70
A novel method to estimate the absorption rate constant for two-compartment model fitted drugs without intravenous pharmacokinetic data	70
Potential role of gut microbes in the efficacy and toxicity of immune checkpoints inhibitors	69
Editorial: Gastrointestinal and Liver Effects of Fruits and Their Synergism With Drug Therapy: Exploring Possible Mechanisms of Action	68
Key Considerations for Phase 2 or 3 Clinical Study Design of Anti-Inflammatory Agent for COVID-19 Treatment	68
Editorial: Targeting Neuro-Immuno-Vascular Interactions in the Brain and the Periphery	67
3D-QSAR, design, molecular docking and dynamics simulation studies of novel 6-hydroxybenzothiazole-2-carboxamides as potentially potent and selective monoamine oxidase B inhibitors	66
The Impact of Dabigatran and Rivaroxaban on Variation of Platelet Activation Biomarkers and DRT Following Percutaneous Left Atrial Appendage Closure	66
P-glycoprotein efflux transporter: a key to pharmacokinetic modeling for methadone clearance in fetuses	66
Perceptions, Expectations, and Experience of Physicians About Pharmacists and Pharmaceutical Care Services in Pakistan: Findings and Implications	66
Editorial: Modulating Vascular Lymphatic Growth in Disease: Current and Potential Pharmacological Approaches for Prevention and Treatment	66
Gentiopicroside improves non-alcoholic steatohepatitis by activating PPARα and suppressing HIF1	66
A review of Psoralea corylifolia L.: a valuable plant with profound biological significance	65
Efficacy and safety of tripterygium glycosides combined with ACEI/ARB on diabetic nephropathy: a meta-analysis	65
Adverse events in different administration routes of amiodarone: a pharmacovigilance study based on the FDA adverse event reporting system	65
RETRACTED: Melatonin Mediates Osteoblast Proliferation Through the STIM1/ORAI1 Pathway	65
Protective effect of resveratrol on retinal damage in glaucoma: a systematic review and meta-analysis of preclinical studies	65
The chiisanoside derivatives present in the leaves of Acanthopanax sessiliflorus activate autophagy through the LRP6/GSK3β axis and thereafter inhibit oxidative stress, thereby counteracting cisplatin	65
Euodiae Fructus: a review of botany, application, processing, phytochemistry, quality control, pharmacology, and toxicology	65
Phenotype-Based HPLC-Q-TOF-MS/MS Coupled With Zebrafish Behavior Trajectory Analysis System for the Identification of the Antidepressant Components in Methanol Extract of Anshen Buxin Six Pills	65
Fosaprepitant as combination therapy to prevent chemotherapy-induced vomiting in children: a meta-analysis	65
Efferocytosis-related gene IL33 predicts prognosis and immune response and mediates proliferation and migration in vitro and in vivo of breast cancer	65
Jiawei Suanzaoren decoction for the treatment of perimenopausal insomnia: clinical observation and experimental study	65
Study and exploration of the pharmacokinetics of traditional Tibetan medicine Ruyi Zhenbao tablets after single and long-term administration	64
Editorial: Interplays and Functions of Gaseous Mediators: From Underlying Mechanisms to Therapeutic Approaches in Cardiovascular Diseases	64
Hydralazine Associated With Reduced Therapeutic Phlebotomy Frequency in a Nationwide Cohort Study: Real-World Effectiveness for Drug Repurposing	64
Influenza vaccination and risk of atrial fibrillation in patients with gout: A nationwide population-based cohort study	63
iTRAQ-Based Proteomics Reveals Gu-Ben-Fang-Xiao Decoction Alleviates Airway Remodeling via Reducing Extracellular Matrix Deposition in a Murine Model of Chronic Remission Asthma	63
Editorial: Drugging p53 for non-cancer diseases	63
Analysing breast cancer survivors’ acceptance profiles for using an electronic pillbox connected to a smartphone application using Seintinelles, a French community-based research tool	63
Editorial: Novel modalities in cancer diagnostics and therapeutics	63
HAS 1: A natural product from soil-isolated Streptomyces species with potent activity against cutaneous leishmaniasis caused by Leishmania tropica	62
Reverse Remodeling in Human Heart Failure after Cardiac Resynchronization Therapy Is Associated With Reduced RHO-Kinase Activation	62
A Tau Pathogenesis-Based Network Pharmacology Approach for Exploring the Protections of Chuanxiong Rhizoma in Alzheimer’s Disease	62
The preventive effects of ondansetron on chemotherapy-induced nausea and vomiting in adult cancer patients: systematic review from ClinicalTrials.gov	62
Efficacy and safety of Chinese medicine injections in combination with docetaxel and cisplatin for non-small cell lung cancer: a network meta-analysis	62
Immune-Related Adverse Events Associated With Immune Checkpoint Inhibitors for Advanced Non-small Cell Lung Cancer: A Network Meta-Analysis of Randomized Clinical Trials	62
Long-term sedation with remimazolam besylate versus propofol in critically ill patients during invasive mechanical ventilation: a study protocol for a multicenter randomized non-inferior trial	62
Safety Evaluation of Natural Drugs in Chronic Skeletal Disorders: A Literature Review of Clinical Trials in the Past 20 years	61
Optimizing antidotal treatment with the oral HSP90 inhibitor TAS-116 against hydrochloric acid-induced pulmonary fibrosis in mice	61
The Adverse Cardiovascular Effects and Cardiotoxicity of Kratom (Mitragyna speciosa Korth.): A Comprehensive Review	61
Canagliflozin Prevents Lipid Accumulation, Mitochondrial Dysfunction, and Gut Microbiota Dysbiosis in Mice With Diabetic Cardiovascular Disease	61
In vitro and in silico studies reveal antidiabetic properties of arylbenzofurans from the root bark of Morus mesozygia Stapf	60
Advances in the Study of the Ubiquitin-Editing Enzyme A20	60
Short-Chain Naphthoquinone Protects Against Both Acute and Spontaneous Chronic Murine Colitis by Alleviating Inflammatory Responses	59
Citrullus colocynthis (L.) Schrad (Bitter Apple Fruit): Promising Traditional Uses, Pharmacological Effects, Aspects, and Potential Applications	59
Discovery of inhibitors of protein tyrosine phosphatase 1B contained in a natural products library from Mexican medicinal plants and fungi using a combination of enzymatic and in silico methods**	59
Mechanisms by which kidney-tonifying Chinese herbs inhibit osteoclastogenesis: Emphasis on immune cells	59
Pharmacological Treatment of Diabetic and Non-Diabetic Patients With Coronary Artery Disease in the Real World of General Practice	59
Potential Treat-to-Target Approach for Methamphetamine Use Disorder: A Pilot Study of Adenosine 2A Receptor Antagonist With Positron Emission Tomography	58
Dissection of the Functional Mechanism of Human Gut Bacterial Strain AD16 by Secondary Metabolites’ Identification, Network Pharmacology, and Experimental Validation	58
Construction of the Enterococcal Strain Expressing Immunogenic Fragment of SARS-Cov-2 Virus	58
Clinical characteristics and risk factors analysis of 505 cases of infusion reactions in a tertiary hospital	58
Development of a pediatric physiologically-based pharmacokinetic model to support recommended dosing of atezolizumab in children with solid tumors	57
Apigenin protects against ischemic stroke by increasing DNA repair	57
Real-world antibiotic use in treating acute exacerbations of chronic obstructive pulmonary disease (AECOPD) in China: Evidence from the ACURE study	57
Jiegeng Decoction Potentiates the Anticancer Efficacy of Paclitaxel in vivo and in vitro	57
Past and future of an IMI-PharmaTrain (IMI-PhT)-initiated multinational pharmaceutical medicine course at the Semmelweis University in Hungary	56
Combined Oral and Topical Application of Pumpkin (Cucurbita pepo L.) Alleviates Contact Dermatitis Associated With Depression Through Downregulation Pro-Inflammatory Cytokines	55
Therapeutic Targeting of Transcription Factors to Control the Cytokine Release Syndrome in COVID-19	55
Dioscin Reduces Vascular Damage in the Retina of db/db Mice by Inhibiting the VEGFA Signaling Pathway	55
Fraxin Promotes the Activation of Nrf2/ARE Pathway via Increasing the Expression of Connexin43 to Ameliorate Diabetic Renal Fibrosis	55
Confirming the efficacy and safety of CDK4/6 inhibitors in the first-line treatment of HR+ advanced breast cancer: a systematic review and meta-analysis	54
Retrospective analysis of the effect of SGLT-2 inhibitors on renal function in patients with type 2 diabetes in the real world	54
The Role of High-Density Lipoprotein in COVID-19	54
Real-world pharmacovigilance analysis of galsulfase: a study based on the FDA adverse event reporting system (FAERS) database	54
Forsythiasides-Rich Extract From Forsythiae Fructus Inhibits Mast Cell Degranulation by Enhancing Mitochondrial Ca2+ Uptake	53
Fucoxanthin: A Promising Phytochemical on Diverse Pharmacological Targets	53
Noncoding RNAs as a novel approach to target retinopathy of prematurity	53
A practical assessment protocol for clinically relevant P-glycoprotein-mediated drug-drug interactions	53
Spatiotemporal delivery of multiple components of rhubarb-astragalus formula for the sysnergistic treatment of renal fibrosis	52
Ganoderma lucidum: Unutilized natural medicine and promising future solution to emerging diseases in Africa	52
Natural products from plants and microorganisms: Novel therapeutics for chronic kidney disease via gut microbiota regulation	52
DNA methylation inhibitors adverse reaction characteristic analysis: a descriptive analysis from WHO-VigiAccess	52
Knowledge and practices related to antibiotic use among women in Malang, Indonesia	52
Pichia pastoris secreted peptides crossing the blood-brain barrier and DSIP fusion peptide efficacy in PCPA-induced insomnia mouse models	52
Identifying optimal PD-1/PD-L1 inhibitors in first-line treatment of patients with advanced squamous non-small cell lung cancer in China: Updated systematic review and network meta-analysis	52
The effect of sodium-glucose cotransporter 2 inhibitors on biomarkers of inflammation: A systematic review and meta-analysis of randomized controlled trials	52

An insight into pharmacokinetics and dose optimization of antimicrobials agents in elderly patients	52
Cholesterol metabolism in the regulation of inflammatory responses	52
The Bioequivalence of Emulsified Isoflurane With a New Formulation of Emulsion: A Single-Center, Single-Dose, Double-Blinded, Randomized, Two-Period Crossover Study	51
The modulation of gut microbiota by herbal medicine to alleviate diabetic kidney disease – A review	51
Artemisitene Alters LPS-Induced Oxidative stress, inflammation and Ferroptosis in Liver Through Nrf2/HO-1 and NF-kB Pathway	51
Systematic transcriptome analysis reveals molecular mechanisms and indications of bupleuri radix	51
Mapping the regulatory landscape of AI in healthcare in Africa	51
Efficacy analysis of splint combined with platelet-rich plasma in the treatment of temporomandibular joint osteoarthritis	51
Dandelion extract inhibits triple-negative breast cancer cell proliferation by interfering with glycerophospholipids and unsaturated fatty acids metabolism	51
Phenethylisothiocyanate Potentiates Platinum Therapy by Reversing Cisplatin Resistance in Cervical Cancer	50
ACSL4 as a Potential Target and Biomarker for Anticancer: From Molecular Mechanisms to Clinical Therapeutics	50
Identification of the Key Role of NF-κB Signaling Pathway in the Treatment of Osteoarthritis With Bushen Zhuangjin Decoction, a Verification Based on Network Pharmacology Approach	50
Danhong injection attenuates doxorubicin-induced cardiotoxicity in rats via suppression of apoptosis: network pharmacology analysis and experimental validation	50
Efficacy and safety of concomitant use of proton pump inhibitors with aspirin-clopidogrel dual antiplatelet therapy in coronary heart disease: A systematic review and meta-analysis	50
BNSTAVGABA-PVNCRF Circuit Regulates Visceral Hypersensitivity Induced by Maternal Separation in Vgat-Cre Mice	50
Effect of X-ray radiation on the pharmacokinetics of apatinib in vivo in rats	50
Risk of herpes zoster associated with JAK inhibitors in immune-mediated inflammatory diseases: a systematic review and network meta-analysis	50
Understanding Kratom Use: A Guide for Healthcare Providers	49
Hordenine Protects Against Lipopolysaccharide-Induced Acute Lung Injury by Inhibiting Inflammation	49
Galloflavin Relieves the Malignant Behavior of Colorectal Cancer Cells in the Inflammatory Tumor Microenvironment	49
Evaluation of Kratom Opioid Derivatives as Potential Treatment Option for Alcohol Use Disorder	49
Research Progress of Chinese Herbal Medicine Intervention in Renal Interstitial Fibrosis	49
Nox4 Promotes RANKL-Induced Autophagy and Osteoclastogenesis via Activating ROS/PERK/eIF-2α/ATF4 Pathway	49
Shugan Jieyu Capsule in Post-Stroke Depression Treatment: From Molecules to Systems	49
FDX1 can Impact the Prognosis and Mediate the Metabolism of Lung Adenocarcinoma	49
Effects of plant protease inhibitors (Pep-3-EcTI, Pep-BbKI, and Pep-BrTI) versus corticosteroids on inflammation, remodeling, and oxidative stress in an asthma–COPD (ACO) model	48
Exosome: The “Off-the-Shelf” Cellular Nanocomponent as a Potential Pathogenic Agent, a Disease Biomarker, and Neurotherapeutics	48
Inhaled Corticosteroids and the Pneumonia Risk in Patients With Chronic Obstructive Pulmonary Disease: A Meta-analysis of Randomized Controlled Trials	48
Treatment of Poor Sperm Quality and Erectile Dysfunction With Oral Pentoxifylline: A Systematic Review	48
Insights Into the Properties, Biological Functions, and Regulation of USP21	48
Paeoniflorin Suppresses TBHP-Induced Oxidative Stress and Apoptosis in Human Umbilical Vein Endothelial Cells via the Nrf2/HO-1 Signaling Pathway and Improves Skin Flap Survival	48
Recent developments of phosphodiesterase inhibitors: Clinical trials, emerging indications and novel molecules	48
Caspase-9: A Multimodal Therapeutic Target With Diverse Cellular Expression in Human Disease	48
Jinmaitong Alleviates Diabetic Neuropathic Pain Through Modulation of NLRP3 Inflammasome and Gasdermin D in Dorsal Root Ganglia of Diabetic Rats	48
Editorial: Targeting the Chemoattractant System in Inflammation	47
The efficacy of traditional chinese medicine combined with hyperthermic intraperitoneal chemotherapy for malignant ascites: A systematic review and meta-analysis	47
Case Report: Good cardiac tolerance to Toripalimab in a CVD patient with oral melanoma	47
α7 Nicotinic Acetylcholine Receptor May Be a Pharmacological Target for Perioperative Neurocognitive Disorders	47
UGT2B7 gene polymorphism and linkage disequilibrium in pediatric epileptic patients and their influence on sodium valproate monotherapy: A cohort study	46
Editorial: Chromatographic analytical methods for quantifying newly marketed targeted antitumor drugs	46
Z1456467176 alleviates gouty arthritis by allosterically modulating P2X7R to inhibit NLRP3 inflammasome activation	46
Oral energy supplementation improves nutritional status in hemodialysis patients with protein–energy wasting: A pilot study	46
Fragment-pair based drug molecule solubility prediction through attention mechanism	46
Tormentic Acid Ameliorates Hepatic Fibrosis in vivo by Inhibiting Glycerophospholipids Metabolism and PI3K/Akt/mTOR and NF-κB Pathways: Based on Transcriptomics and Metabolomics	46
Case report: Clinical management of recurrent small cell lung cancer transformation complicated with lung cancer-induced acute pancreatitis after lung adenocarcinoma surgery	46
Impairment of exocytotic transmitter release by decynium-22 through an inhibition of ion channels	46
L-Theanine Alleviates IMQ-Induced Psoriasis Like Skin Inflammation by Downregulating the Production of IL-23 and Chemokines	45
Mouse promyelocytic leukemia zinc finger protein (PLZF) regulates hepatic lipid and glucose homeostasis dependent on SIRT1	45
Rhynchophylline Regulates Calcium Homeostasis by Antagonizing Ryanodine Receptor 2 Phosphorylation to Improve Diabetic Cardiomyopathy	45
Pharmacoepidemiology Research-Real-World Evidence for Decision Making	45
Targeting the Endothelium to Achieve Cardioprotection	45
Evaluation of the Current Therapeutic Approaches for COVID-19: A Systematic Review and a Meta-analysis	45
Tailored therapy for Helicobacter pylori eradication: A systematic review and meta-analysis	45
Saffron (Crocus sativus) and its constituents in ovalbumin-induced asthma model: a preclinical systematic review and meta-analysis	45
Tibetan mineral-herbal medicine Zuotai alleviates the depressive-like behaviors in chronic restraint-stressed mice while regulating stress hormone, inflammation and monoamine	45
Hurdles and signposts on the road to virtual control groups—A case study illustrating the influence of anesthesia protocols on electrolyte levels in rats	45
Decrementally cost-effective health technologies in non-inferiority studies: A systematic review	45
Purine metabolism-related gene expression signature predicts survival outcome and indicates immune microenvironment profile of gliomas	44
Editorial: Crosstalk between cancer-associated fibroblasts and tumor cells in the tumor microenvironment: an emerging target of anti-cancer immunotherapy	44
Fabry disease: Mechanism and therapeutics strategies	44
Cost-utility analysis of using paliperidone palmitate in schizophrenia in China	44
Research advances in the therapy of metabolic syndrome	44
Three-Drug Regimens Containing Integrase Inhibitor Show Good Efficacy and Safety in Treatment-Naive Patients With HIV-1: A Bayesian Analysis	44
Adding of apatinib and camrelizumab to overcome de novo trastuzumab resistance of HER2-positive gastric cancer: A case report and literature review	44
A Novel COVID-19-Related Drug Discovery Approach Based on Non-Equidimensional Data Clustering	43
Clinical study of lenvatinib in the treatment of hepatitis virus-related hepatocellular carcinoma and antiviral therapy	43
Treatment Strategy for Chronic Obstructive Parotitis Related to Diabetes: A Retrospective Analysis of 12 Cases	43
Effects of public reporting of prescription indicators on patient choices: evidence from propensity scores matching	43
Utility of a Laboratory Alert System for Detecting Adverse Drug Reactions in Hospitalised Patients: Hyponatremia and Rhabdomyolysis	43
Micro-simulation insights into the functional and mechanistic understanding of glycyrrhizin against asthma	43
Antidiabetic effects of Andrographis paniculata supplementation on biochemical parameters, inflammatory responses, and oxidative stress in canine diabetes	43
Who Suffers From Pharmaceutical Poverty and What Are Their Needs? Evidence From a Spanish Region	43
Kaixin-San improves Aβ-induced synaptic plasticity inhibition by affecting the expression of regulation proteins associated with postsynaptic AMPAR expression	43
Novel Oxovanadium Complex VO(hntdtsc)(NPIP): Anticancer Activity and Mechanism of Action on HeLa Cells	43
Impact of domiciliary administration of NSAIDs on COVID-19 hospital outcomes: an unCoVer analysis	43
Editorial: Cardio-Protection and Heart Repair: New Drugs, Targets and Approaches	42
Riddle of the Sphinx: Emerging Role of Transfer RNAs in Human Cancer	42
Editorial: Nutraceuticals modulation for oxidative stress in disease and health	42
Editorial: Dissecting Traditional Medicine via Chemical and Biochemical Techniques: Advanced Analytics and Novel Paradigms	42
Commentary: Anti-hyperplasia effects of total saponins from phytolaccae radix in rats with mammary gland hyperplasia via inhibition of proliferation and induction of apoptosis	42
Unbiased transcriptome mapping and modeling identify candidate genes and compounds of osteoarthritis	42
Risk factors, clinical correlates, and social functions of Chinese schizophrenia patients with drug-induced parkinsonism: A cross-sectional analysis of a multicenter, observational, real-world, prospe	42
Editorial: Apoptosis Induction/Suppression: A Feasible Approach for Natural Products to Treatment of Diseases	42
Editorial: Medication safety in COVID-19 management, Volume II	41
Decylubiquinone Inhibits Colorectal Cancer Growth Through Upregulating Sirtuin2	41
BCR-ABL1-positive acute lymphoblastic leukemia following successful treatment of acute promyelocytic leukemia: case report	41
Interaction of Serum Alkaline Phosphatase and Folic Acid Treatment on Chronic Kidney Disease Progression in Treated Hypertensive Adults	41
L-carnitine prevents lenvatinib-induced muscle toxicity without impairment of the anti-angiogenic efficacy	41
A specific SNP-based multiplex PCR assay for the simultaneous identification of two biological ingredients for the Chinese patent medicine, Danggui Buxue pill	41
Isoliquiritigenin Alleviates Semen Strychni-Induced Neurotoxicity by Restoring the Metabolic Pathway of Neurotransmitters in Rats	41
Acute pharmacological profile of 2C-B-Fly-NBOMe in male Wistar rats—pharmacokinetics, effects on behaviour and thermoregulation	41
Biomarker identification and pathway analysis of Astragalus membranaceus and Curcuma zedoaria couplet medicines on adenine-induced chronic kidney disease in rats based on metabolomics	41
Case Report: The Complexities of Managing Medications and the Importance of Deprescribing Anticholinergics in Older Adults	41
Magnetic Resonance Imaging Investigation of Neuroplasticity After Ischemic Stroke in Tetramethylpyrazine-Treated Rats	41
Editorial: Oral mucosa and disorders: from drug discovery to development and translation	40