Frontiers in Pharmacology

Article	Citations
Toxic Mechanisms of Five Heavy Metals: Mercury, Lead, Chromium, Cadmium, and Arsenic	861
Turmeric and Its Major Compound Curcumin on Health: Bioactive Effects and Safety Profiles for Food, Pharmaceutical, Biotechnological and Medicinal Applications	342
The Bone Extracellular Matrix in Bone Formation and Regeneration	331
Advances in Oral Drug Delivery	287
Cell-Penetrating Peptides in Diagnosis and Treatment of Human Diseases: From Preclinical Research to Clinical Application	274
Perceptions of healthcare professionals and patients on the role of the pharmacist in TB management in Pakistan: A qualitative study	267
Biodegradable Polymeric Nanoparticles for Drug Delivery to Solid Tumors	257
Molecular Sets (MOSES): A Benchmarking Platform for Molecular Generation Models	252
Herb and Spices in Colorectal Cancer Prevention and Treatment: A Narrative Review	225
Dietary Polyphenols and Their Role in Oxidative Stress-Induced Human Diseases: Insights Into Protective Effects, Antioxidant Potentials and Mechanism(s) of Action	224
Advances in Oral Drug Delivery for Regional Targeting in the Gastrointestinal Tract - Influence of Physiological, Pathophysiological and Pharmaceutical Factors	219
Comparative effectiveness of individualized longer and standardized shorter regimens in the treatment of multidrug resistant tuberculosis in a high burden country	215
Nanocurcumin: A Promising Candidate for Therapeutic Applications	208
Modeling Parkinson’s Disease With the Alpha-Synuclein Protein	193
Herbal Medicine for Cardiovascular Diseases: Efficacy, Mechanisms, and Safety	181
COVID-19: Is There Evidence for the Use of Herbal Medicines as Adjuvant Symptomatic Therapy?	168
PI3K/AKT Signal Pathway: A Target of Natural Products in the Prevention and Treatment of Alzheimer’s Disease and Parkinson’s Disease	167
DNA Repair Pathways in Cancer Therapy and Resistance	166
Activation of PI3K/AKT/mTOR Pathway Causes Drug Resistance in Breast Cancer	161
The Therapeutic Potential of Anthocyanins: Current Approaches Based on Their Molecular Mechanism of Action	148
Uric Acid and Cardiovascular Disease: An Update From Molecular Mechanism to Clinical Perspective	145
Histone Deacetylases Inhibitors in Neurodegenerative Diseases, Neuroprotection and Neuronal Differentiation	145
From Animal Poisons and Venoms to Medicines: Achievements, Challenges and Perspectives in Drug Discovery	145
Discovering Anti-Cancer Drugs via Computational Methods	144
A Snapshot of the Global Race for Vaccines Targeting SARS-CoV-2 and the COVID-19 Pandemic	142

SIRT1 Activation by Natural Phytochemicals: An Overview	141
PROTAC: An Effective Targeted Protein Degradation Strategy for Cancer Therapy	140
The Role of the CXCL12/CXCR4/CXCR7 Chemokine Axis in Cancer	140
Overview of OxLDL and Its Impact on Cardiovascular Health: Focus on Atherosclerosis	138
Pharmacological Properties of Chalcones: A Review of Preclinical Including Molecular Mechanisms and Clinical Evidence	137
Comprehensive Analysis of Cuproptosis-Related Genes in Immune Infiltration and Prognosis in Melanoma	135
PD-1/PD-L1 Checkpoint Inhibitors in Tumor Immunotherapy	133
Dopamine Receptor Subtypes, Physiology and Pharmacology: New Ligands and Concepts in Schizophrenia	132
Phytosterols: From Preclinical Evidence to Potential Clinical Applications	131
Fluvoxamine: A Review of Its Mechanism of Action and Its Role in COVID-19	130
Response to the Novel Corona Virus (COVID-19) Pandemic Across Africa: Successes, Challenges, and Implications for the Future	128
Unraveling Plant Natural Chemical Diversity for Drug Discovery Purposes	123
Medicinal Plants as Sources of Active Molecules Against COVID-19	121
Therapeutic Potential of Centella asiatica and Its Triterpenes: A Review	118
Non-Alcoholic Steatohepatitis: A Review of Its Mechanism, Models and Medical Treatments	113
AKT Inhibitors: New Weapons in the Fight Against Breast Cancer?	113
Knowledge Mapping of Drug-Induced Liver Injury: A Scientometric Investigation (2010–2019)	112
The Pharmacological Action of Kaempferol in Central Nervous System Diseases: A Review	108
Neurodegenerative Disease and the NLRP3 Inflammasome	108
A Systematic Review of Plants With Antibacterial Activities: A Taxonomic and Phylogenetic Perspective	108
Indian Medicinal Plants and Formulations and Their Potential Against COVID-19–Preclinical and Clinical Research	107
Oral Curcumin With Piperine as Adjuvant Therapy for the Treatment of COVID-19: A Randomized Clinical Trial	105
Resveratrol Modulates the Gut Microbiota and Inflammation to Protect Against Diabetic Nephropathy in Mice	105
Clinically-Relevant ABC Transporter for Anti-Cancer Drug Resistance	105
Cellular and Molecular Pathways of COVID-19 and Potential Points of Therapeutic Intervention	103
P2X7 in Cancer: From Molecular Mechanisms to Therapeutics	103
Cellular Mechanisms of Liver Fibrosis	100
Novel and Emerging Therapies for Inflammatory Bowel Disease	99
Anti-SARS-CoV Natural Products With the Potential to Inhibit SARS-CoV-2 (COVID-19)	99
Mesenchymal Stem Cell–Derived Exosomes: A Promising Biological Tool in Nanomedicine	99
Combination of Ruxolitinib and Eculizumab for Treatment of Severe SARS-CoV-2-Related Acute Respiratory Distress Syndrome: A Controlled Study	97
The Evasion Mechanisms of Cancer Immunity and Drug Intervention in the Tumor Microenvironment	97
Heavy Metal Contaminations in Herbal Medicines: Determination, Comprehensive Risk Assessments, and Solutions	97
Challenges for Drug Repurposing in the COVID-19 Pandemic Era	96
Pharmacogenetics Guidelines: Overview and Comparison of the DPWG, CPIC, CPNDS, and RNPGx Guidelines	94
Recent Advances in NAMPT Inhibitors: A Novel Immunotherapic Strategy	94
Neutrophilia and NETopathy as Key Pathologic Drivers of Progressive Lung Impairment in Patients With COVID-19	94
Interplay of EMT and CSC in Cancer and the Potential Therapeutic Strategies	92
A Review on the Potential Use of Medicinal Plants From Asteraceae and Lamiaceae Plant Family in Cardiovascular Diseases	92
Current Prevention of COVID-19: Natural Products and Herbal Medicine	92
The Role of Oxidative Stress and Natural Antioxidants in Ovarian Aging	91
Drug Shortage: Causes, Impact, and Mitigation Strategies	91
Cinnamomum Species: Bridging Phytochemistry Knowledge, Pharmacological Properties and Toxicological Safety for Health Benefits	90
G Protein-Coupled Receptors in Taste Physiology and Pharmacology	90
A Comprehensive Review on the Therapeutic Potential of Curcuma longa Linn. in Relation to its Major Active Constituent Curcumin	90
Baicalin Prevents Myocardial Ischemia/Reperfusion Injury Through Inhibiting ACSL4 Mediated Ferroptosis	89
Resveratrol and Neuroprotection: Impact and Its Therapeutic Potential in Alzheimer's Disease	88
The Drug Repurposing for COVID-19 Clinical Trials Provide Very Effective Therapeutic Combinations: Lessons Learned From Major Clinical Studies	88
Passiflora edulis: An Insight Into Current Researches on Phytochemistry and Pharmacology	88
Advanced Approaches to Breast Cancer Classification and Diagnosis	86

Repurposing Drugs, Ongoing Vaccine, and New Therapeutic Development Initiatives Against COVID-19	86
Immunosuppressive Drugs and COVID-19: A Review	85
Remimazolam: Non-Clinical and Clinical Profile of a New Sedative/Anesthetic Agent	84
Immune Checkpoint Inhibitor-Related Cytokine Release Syndrome: Analysis of WHO Global Pharmacovigilance Database	84
Natural Compounds With Antimicrobial and Antiviral Effect and Nanocarriers Used for Their Transportation	82
Exploring Phytochemicals for Combating Antibiotic Resistance in Microbial Pathogens	82
Celastrol: A Review of Useful Strategies Overcoming its Limitation in Anticancer Application	81
SIRT1 and SIRT2 Activity Control in Neurodegenerative Diseases	80
FDX1 can Impact the Prognosis and Mediate the Metabolism of Lung Adenocarcinoma	80
Kuijieyuan Decoction Improved Intestinal Barrier Injury of Ulcerative Colitis by Affecting TLR4-Dependent PI3K/AKT/NF-κB Oxidative and Inflammatory Signaling and Gut Microbiota	79
Targeting the Integrated Stress Response in Cancer Therapy	79
Psychedelic Communitas: Intersubjective Experience During Psychedelic Group Sessions Predicts Enduring Changes in Psychological Wellbeing and Social Connectedness	79
Efficacy, Chemical Constituents, and Pharmacological Actions of Radix Paeoniae Rubra and Radix Paeoniae Alba	79
Peroxisome Proliferator-Activated Receptors: Experimental Targeting for the Treatment of Inflammatory Bowel Diseases	78
Curcumin as a Potential Treatment for COVID-19	77
The Role of Tumor Inflammatory Microenvironment in Lung Cancer	77
Polyphenols as Antitumor Agents Targeting Key Players in Cancer-Driving Signaling Pathways	76
DPP4 and ACE2 in Diabetes and COVID-19: Therapeutic Targets for Cardiovascular Complications?	76
Combination of an Autophagy Inducer and an Autophagy Inhibitor: A Smarter Strategy Emerging in Cancer Therapy	76
Matrine: A Promising Natural Product With Various Pharmacological Activities	76
Clinical Insights Into Novel Immune Checkpoint Inhibitors	76
Like Cures Like: Pharmacological Activity of Anti-Inflammatory Lipopolysaccharides From Gut Microbiome	75
Targeting Neutrophils to Treat Acute Respiratory Distress Syndrome in Coronavirus Disease	75
Hyaluronic Acid-Mediated Drug Delivery System Targeting for Inflammatory Skin Diseases: A Mini Review	75
Neuropharmacological Effects of Quercetin: A Literature-Based Review	74
Formation, Signaling and Occurrence of Specialized Pro-Resolving Lipid Mediators—What is the Evidence so far?	74
Genistein: A Review on its Anti-Inflammatory Properties	73
Chinese Patent Medicines in the Treatment of Coronavirus Disease 2019 (COVID-19) in China	73
Epilepsy-Related Voltage-Gated Sodium Channelopathies: A Review	73
Functions and Diseases of the Retinal Pigment Epithelium	72
Clinical Review: Navitoclax as a Pro-Apoptotic and Anti-Fibrotic Agent	72
Progress in the Understanding of the Mechanism of Tamoxifen Resistance in Breast Cancer	72
The Mechanism of Ferroptosis and Applications in Tumor Treatment	72
Eicosanoids in Cancer: New Roles in Immunoregulation	71
Herbal Medicine in the Treatment of Non-Alcoholic Fatty Liver Diseases-Efficacy, Action Mechanism, and Clinical Application	70
Baicalin Inhibits Ferroptosis in Intracerebral Hemorrhage	70
Idiopathic Pulmonary Fibrosis: An Update on Pathogenesis	69
The Biological Functions and Clinical Applications of Integrins in Cancers	69
The Potential Role of Heparin in Patients With COVID-19: Beyond the Anticoagulant Effect. A Review	69
The Noradrenergic System in Parkinson’s Disease	69
Potential Therapeutic Options for COVID-19: Current Status, Challenges, and Future Perspectives	67
Pyroptosis in the Initiation and Progression of Atherosclerosis	67
Kaempferol Protects Against Cerebral Ischemia Reperfusion Injury Through Intervening Oxidative and Inflammatory Stress Induced Apoptosis	67
Pharmacotherapy of Behavioral and Psychological Symptoms of Dementia: State of the Art and Future Progress	67
Case Report: Central Retinal Artery Occlusion in a COVID-19 Patient	66
Pharmacological Effects of Salvianolic Acid B Against Oxidative Damage	66
Fecal Microbiota Transplantation for the Treatment of Inflammatory Bowel Disease: An Update	66
Fisetin Attenuates Doxorubicin-Induced Cardiomyopathy In Vivo and In Vitro by Inhibiting Ferroptosis Through SIRT1/Nrf2 Signaling Pathway Activation	65
Quercetin Attenuates Atherosclerosis via Modulating Oxidized LDL-Induced Endothelial Cellular Senescence	65
Safety and Efficacy of Bromodomain and Extra-Terminal Inhibitors for the Treatment of Hematological Malignancies and Solid Tumors: A Systematic Study of Clinical Trials	65
Mechanisms of Chemotherapy-Induced Neurotoxicity	64
The Inhibitory Effect of 6-Gingerol on Ubiquitin-Specific Peptidase 14 Enhances Autophagy-Dependent Ferroptosis and Anti-Tumor in vivo and in vitro	64
Caspase-9: A Multimodal Therapeutic Target With Diverse Cellular Expression in Human Disease	64
Analysis of Models of Doxorubicin-Induced Cardiomyopathy in Rats and Mice. A Modern View From the Perspective of the Pathophysiologist and the Clinician	64
Traditional Chinese Medicine: Role in Reducing β-Amyloid, Apoptosis, Autophagy, Neuroinflammation, Oxidative Stress, and Mitochondrial Dysfunction of Alzheimer’s Disease	64
Eicosanoids in Cancer: Prostaglandin E2 Receptor 4 in Cancer Therapeutics and Immunotherapy	64
Calming the Storm: Natural Immunosuppressants as Adjuvants to Target the Cytokine Storm in COVID-19	64
Intranasal Delivery of Targeted Nanoparticles Loaded With miR-132 to Brain for the Treatment of Neurodegenerative Diseases	64
Trends in Antidiabetic Drug Discovery: FDA Approved Drugs, New Drugs in Clinical Trials and Global Sales	63
Oxidative Stress and Hyper-Inflammation as Major Drivers of Severe COVID-19 and Long COVID: Implications for the Benefit of High-Dose Intravenous Vitamin C	63
Analgesic Effect of Acetaminophen: A Review of Known and Novel Mechanisms of Action	63
An Update on Antiviral Therapy Against SARS-CoV-2: How Far Have We Come?	63
Repurposing Sigma-1 Receptor Ligands for COVID-19 Therapy?	63
Therapeutic Alliance and Rapport Modulate Responses to Psilocybin Assisted Therapy for Depression	63
Chlorogenic Acid Improves NAFLD by Regulating gut Microbiota and GLP-1	62
Integrated PPI- and WGCNA-Retrieval of Hub Gene Signatures Shared Between Barrett's Esophagus and Esophageal Adenocarcinoma	62
Best Practice in the chemical characterisation of extracts used in pharmacological and toxicological research—The ConPhyMP—Guidelines12	62
Software Tools for Model-Informed Precision Dosing: How Well Do They Satisfy the Needs?	61
Recommendation of Antimicrobial Dosing Optimization During Continuous Renal Replacement Therapy	61
PD-1/PD-L1 Based Combinational Cancer Therapy: Icing on the Cake	61
Insight Into the Prospects for RNAi Therapy of Cancer	61
Traditional Herbal Medicines, Bioactive Metabolites, and Plant Products Against COVID-19: Update on Clinical Trials and Mechanism of Actions	60
The Therapeutic Landscape of Rheumatoid Arthritis: Current State and Future Directions	60
Cannabidiol as a Therapeutic Target: Evidence of its Neuroprotective and Neuromodulatory Function in Parkinson’s Disease	60
Lactoferrin Against SARS-CoV-2: In Vitro and In Silico Evidences	60
Metformin: A Novel Weapon Against Inflammation	60
A Review of the Pharmacological Properties of Psoralen	60
Postoperative Ileus and Postoperative Gastrointestinal Tract Dysfunction: Pathogenic Mechanisms and Novel Treatment Strategies Beyond Colorectal Enhanced Recovery After Surgery Protocols	59
Multi-Target Approaches in Metabolic Syndrome	59
Calcium Permeable Channels in Cancer Hallmarks	59

COVID-19 Therapeutic Options Under Investigation	59
Phytochemicals as a Complement to Cancer Chemotherapy: Pharmacological Modulation of the Autophagy-Apoptosis Pathway	59
Mitochondria Targeted Viral Replication and Survival Strategies—Prospective on SARS-CoV-2	58
Cordyceps spp.: A Review on Its Immune-Stimulatory and Other Biological Potentials	58
Sinapic Acid Ameliorates the Progression of Streptozotocin (STZ)-Induced Diabetic Nephropathy in Rats via NRF2/HO-1 Mediated Pathways	58
JAK/STAT Signaling: Molecular Targets, Therapeutic Opportunities, and Limitations of Targeted Inhibitions in Solid Malignancies	58
Dysfunctional Vascular Endothelium as a Driver of Atherosclerosis: Emerging Insights Into Pathogenesis and Treatment	57
Tanshinone IIA: A Review of its Anticancer Effects	57
Chemotherapeutics-Induced Intestinal Mucositis: Pathophysiology and Potential Treatment Strategies	57
Possible Benefits of Faecalibacterium prausnitzii for Obesity-Associated Gut Disorders	57
NSAID–Gut Microbiota Interactions	57
Improvement of Gold Nanorods in Photothermal Therapy: Recent Progress and Perspective	57
Untargeted Metabolomic Analysis of the Effects and Mechanism of Nuciferine Treatment on Rats With Nonalcoholic Fatty Liver Disease	57
The Role of Interleukin-8 in Lung Inflammation and Injury: Implications for the Management of COVID-19 and Hyperinflammatory Acute Respiratory Distress Syndrome	57
Drug Repurposing Screen for Compounds Inhibiting the Cytopathic Effect of SARS-CoV-2	56
Myricetin Inhibits SARS-CoV-2 Viral Replication by Targeting Mpro and Ameliorates Pulmonary Inflammation	56
Accelerating Therapeutics for Opportunities in Medicine: A Paradigm Shift in Drug Discovery	56
Understanding the role of the gut microbiome in gastrointestinal cancer: A review	56
Preliminary Experience With Low Molecular Weight Heparin Strategy in COVID-19 Patients	56
α1-Adrenergic Receptors in Neurotransmission, Synaptic Plasticity, and Cognition	56
Application of Pharmacokinetic-Pharmacodynamic Modeling in Drug Delivery: Development and Challenges	56
Potential of Neglected and Underutilized Yams (Dioscorea spp.) for Improving Nutritional Security and Health Benefits	56
Methylene Blue Inhibits the SARS-CoV-2 Spike–ACE2 Protein-Protein Interaction–a Mechanism that can Contribute to its Antiviral Activity Against COVID-19	55
Efficacy and Safety of Sophora flavescens (Kushen) Based Traditional Chinese Medicine in the Treatment of Ulcerative Colitis: Clinical Evidence and Potential Mechanisms	55
Efficacy and Safety of Probiotics in Irritable Bowel Syndrome: A Systematic Review and Meta-Analysis	55
Turning the Tide: Natural Products and Natural-Product-Inspired Chemicals as Potential Counters to SARS-CoV-2 Infection	55
Integrated Metagenomic and Metabolomic Analyses of the Effect of Astragalus Polysaccharides on Alleviating High-Fat Diet–Induced Metabolic Disorders	55
Necroptosis: A Novel Pathway in Neuroinflammation	55
Interleukin-6: A Novel Target for Cardio-Cerebrovascular Diseases	55
A Systematic Review of the Pharmacology, Toxicology and Pharmacokinetics of Matrine	54
System Xc−/GSH/GPX4 axis: An important antioxidant system for the ferroptosis in drug-resistant solid tumor therapy	54
Toxicomicrobiomics: The Human Microbiome vs. Pharmaceutical, Dietary, and Environmental Xenobiotics	54
The Potential of Antiviral Peptides as COVID-19 Therapeutics	54
MicroRNA as an Important Target for Anticancer Drug Development	54
Transforming Growth Factor-Beta (TGF-β) Signaling in Cancer-A Betrayal Within	54
Advancements in Hydrogel-Based Drug Sustained Release Systems for Bone Tissue Engineering	54
Withania somnifera (L.) Dunal: Opportunity for Clinical Repurposing in COVID-19 Management	53
Gastrin Attenuates Renal Ischemia/Reperfusion Injury by a PI3K/Akt/Bad-Mediated Anti-apoptosis Signaling	53
Post-treatment With Irisin Attenuates Acute Kidney Injury in Sepsis Mice Through Anti-Ferroptosis via the SIRT1/Nrf2 Pathway	53
Bibliometric Analysis of the Inflammasome and Pyroptosis in Brain	53
Glucosinolates From Cruciferous Vegetables and Their Potential Role in Chronic Disease: Investigating the Preclinical and Clinical Evidence	53
The Role of Photoactivated and Non-Photoactivated Verteporfin on Tumor	53
Medicinal Plants in COVID-19: Potential and Limitations	53
Gastroprotective Effect of Sinapic Acid on Ethanol-Induced Gastric Ulcers in Rats: Involvement of Nrf2/HO-1 and NF-κB Signaling and Antiapoptotic Role	52
Potential Natural Products Against Respiratory Viruses: A Perspective to Develop Anti-COVID-19 Medicines	52
Bibliometric Analysis of Global Research on Cancer Photodynamic Therapy: Focus on Nano-Related Research	52
Minor Cannabinoids: Biosynthesis, Molecular Pharmacology and Potential Therapeutic Uses	52
Brucine: A Review of Phytochemistry, Pharmacology, and Toxicology	52
Phytochemistry and Pharmacological Activities of Wolfiporia cocos (F.A. Wolf) Ryvarden & Gilb	52
Formononetin Attenuates Airway Inflammation and Oxidative Stress in Murine Allergic Asthma	52
Deciphering the Pharmacological Mechanisms of Taohe-Chengqi Decoction Extract Against Renal Fibrosis Through Integrating Network Pharmacology and Experimental Validation In Vitro and In Vivo	52
Formulation and Development of Transferrin Targeted Solid Lipid Nanoparticles for Breast Cancer Therapy	52
GLP-1 Receptor Agonists in Diabetic Kidney Disease: From Clinical Outcomes to Mechanisms	52
Enteric Coronavirus Infection and Treatment Modeled With an Immunocompetent Human Intestine-On-A-Chip	51
New Trends in Pharmacological Treatments for Osteoarthritis	51
New Insights Into Gut-Bacteria-Derived Indole and Its Derivatives in Intestinal and Liver Diseases	51
Glomerular Endothelial Cells as Instigators of Glomerular Sclerotic Diseases	50
Monoamine Oxidase Inhibitors: A Review of Their Anti-Inflammatory Therapeutic Potential and Mechanisms of Action	50
Research progress of glutathione peroxidase family (GPX) in redoxidation	50
Heterocyclic Compounds: Pharmacology of Pyrazole Analogs From Rational Structural Considerations	50
A Systematic Review of the Preventive and Therapeutic Effects of Naringin Against Human Malignancies	50
Traditional Chinese Medicine in Depression Treatment: From Molecules to Systems	50
First-Line Immune-Checkpoint Inhibitors in Non-Small Cell Lung Cancer: Current Landscape and Future Progress	50
Targeting Tumor Associated Macrophages to Overcome Conventional Treatment Resistance in Glioblastoma	50
Bilirubin Nanoparticles Reduce Diet-Induced Hepatic Steatosis, Improve Fat Utilization, and Increase Plasma β-Hydroxybutyrate	49
1,2,3-Triazole-Containing Compounds as Anti–Lung Cancer Agents: Current Developments, Mechanisms of Action, and Structure–Activity Relationship	49
Dynamic Interleukin-6 Level Changes as a Prognostic Indicator in Patients With COVID-19	49
Favipiravir Versus Arbidol for Clinical Recovery Rate in Moderate and Severe Adult COVID-19 Patients: A Prospective, Multicenter, Open-Label, Randomized Controlled Clinical Trial	49
Multi-Omics Analysis of Microglial Extracellular Vesicles From Human Alzheimer’s Disease Brain Tissue Reveals Disease-Associated Signatures	49
Paeoniflorin, a Natural Product With Multiple Targets in Liver Diseases—A Mini Review	49
Natural Compounds as Medical Strategies in the Prevention and Treatment of Psychiatric Disorders Seen in Neurological Diseases	49
SARS-CoV-2 Switches ‘on’ MAPK and NFκB Signaling via the Reduction of Nuclear DUSP1 and DUSP5 Expression	49
Effectiveness and Safety of Oral Anticoagulants in Older Patients With Atrial Fibrillation: A Systematic Review and Meta-Analysis	49
Crosstalk Between Dysfunctional Mitochondria and Inflammation in Glaucomatous Neurodegeneration	49
Phytochemistry, Pharmacology and Medicinal Uses of Plants of the Genus Salix: An Updated Review	49
Calcific Aortic Valve Disease-Natural History and Future Therapeutic Strategies	49
Targeting the Wnt/β-Catenin Signaling Pathway as a Potential Therapeutic Strategy in Renal Tubulointerstitial Fibrosis	49
A Comprehensive Account on Recent Progress in Pharmacological Activities of Benzimidazole Derivatives	48
COVID-19: Famotidine, Histamine, Mast Cells, and Mechanisms	48
Impact of TNF-α Inhibitors on Body Weight and BMI: A Systematic Review and Meta-Analysis	48
Innate Immunity in Diabetic Wound Healing: Focus on the Mastermind Hidden in Chronic Inflammatory	48
Sodium–Glucose CoTransporter-2 Inhibitor Empagliflozin Ameliorates Sunitinib-Induced Cardiac Dysfunction via Regulation of AMPK–mTOR Signaling Pathway–Mediated Autophagy	48
Kaempferol Protects Blood Vessels From Damage Induced by Oxidative Stress and Inflammation in Association With the Nrf2/HO-1 Signaling Pathway	48
The Advancing of Selenium Nanoparticles Against Infectious Diseases	48
Patient-Related Risk Factors for Chemotherapy-Induced Nausea and Vomiting: A Systematic Review	48
Role of Neuroinflammation in Autism Spectrum Disorder and the Emergence of Brain Histaminergic System. Lessons Also for BPSD?	48
Therapeutic Effects of Naringin in Rheumatoid Arthritis: Network Pharmacology and Experimental Validation	48
Ferulic Acid Ameliorates Lipopolysaccharide-Induced Barrier Dysfunction via MicroRNA-200c-3p-Mediated Activation of PI3K/AKT Pathway in Caco-2 Cells	48
Phytochemicals: Potential Lead Molecules for MDR Reversal	48
A Comprehensive Review of Clinical Cardiotoxicity Incidence of FDA-Approved Small-Molecule Kinase Inhibitors	47
Natural Anti-Inflammatory Compounds as Drug Candidates for Inflammatory Bowel Disease	47
Bibliometric Analysis of Global Research Trends on Ultrasound Microbubble: A Quickly Developing Field	47
Diabetic Nephropathy: Novel Molecular Mechanisms and Therapeutic Targets	47
A Review of Treatment of Coronavirus Disease 2019 (COVID-19): Therapeutic Repurposing and Unmet Clinical Needs	47
Inulin Exerts Beneficial Effects on Non-Alcoholic Fatty Liver Disease via Modulating gut Microbiome and Suppressing the Lipopolysaccharide-Toll-Like Receptor 4-Mψ-Nuclear Factor-κB-Nod-Like Receptor P	47