Frontiers in Pharmacology

Papers
(The TQCC of Frontiers in Pharmacology is 10. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-12-01 to 2025-12-01.)
ArticleCitations
Editorial: Therapeutic drug monitoring (TDM): a useful tool for pediatric pharmacology applied to routine clinical practice, Volume II735
Efficacy of interventions with live combined Bacillus subtilis and Enterococcus faecium enteric-coated capsules in metabolic associated fatty liver disease patients: a meta-analysis of randomized cont399
Quantum chemical calculations of nitrosamine activation and deactivation pathways for carcinogenicity risk assessment365
Association between hyperuricemia and all-cause mortality in people taken Statins: a retrospective cohort study356
pH-induced conformational changes in the selectivity filter of a potassium channel lead to alterations in its selectivity and permeation properties332
D-cycloserine effects on COPD and depression in a murine experimental model313
GraphTransNet: predicting epilepsy-related genes using a graph-augmented protein language model295
Gegen Qinlian decoction prevents post-ERCP pancreatitis by regulating NLRP3 inflammasome-mediated pyroptosis257
Traditional Chinese Medicine in Treating Primary Podocytosis: From Fundamental Science to Clinical Research225
Unraveling the pathogenic mechanism of a novel filamin a frameshift variant in periventricular nodular heterotopia222
Therapeutic drug monitoring practices of anti-infectives: An Asia-wide cross-sectional survey217
Quantifying the integrated physiological effects of endothelin-1 on cardiovascular and renal function in healthy subjects: a mathematical modeling analysis200
Editorial: Chronic pain: what is the mechanism?191
Long-term clinical course and outcomes of patients with microscopic polyangiitis-associated interstitial lung disease189
Indirect effect of alpha-1-antitrypsin on endotoxin-induced IL-1β secretion from human PBMCs187
Corrigendum: Xenon attenuated neonatal lipopolysaccharide exposure induced neuronal necroptosis and subsequently improved cognition in juvenile rats185
Editorial: Oral mucosa and disorders: from drug discovery to development and translation180
Time trends and regional variations in prices of anticancer medicines in China173
Pre- and post-chemotherapy spermatogenesis in male patients with malignant bone and soft tissue tumors167
The categorizations of vasculogenic mimicry in clear cell renal cell carcinoma unveil inherent connections with clinical and immune features157
Advances in the study of Ophiopogon japonicus polysaccharides: structural characterization, bioactivity and gut microbiota modulation regulation155
Editorial: Impact of anesthetics on cancer behavior and outcome149
Cyclohexene oxide CA, a derivative of zeylenone, exhibits anti-cancer activity in glioblastoma by inducing G0/G1 phase arrest through interference with EZH2146
Unlocking cellular traffic jams: olive oil-mediated rescue of CNG mutant channels145
Erratum: Isoflurane-lipid emulsion injection as an anticonvulsant and neuroprotectant treatment for nerve agent exposure141
Editorial: Interplays and Functions of Gaseous Mediators: From Underlying Mechanisms to Therapeutic Approaches in Cardiovascular Diseases141
Sputum microbe community alterations induced by long-term inhaled corticosteroid use are associated with airway function in chronic obstructive pulmonary disease patients based on metagenomic next-gen139
Ginseng and Polygonum multiflorum formula protects brain function in Alzheimer’s disease137
RRx-001 Exerts Neuroprotection Against LPS-Induced Microglia Activation and Neuroinflammation Through Disturbing the TLR4 Pathway134
Impact of domiciliary administration of NSAIDs on COVID-19 hospital outcomes: an unCoVer analysis134
AduCPI2 alleviates MSU-induced acute gouty arthritis in mice by inhibiting cathepsin S and the C5a-C5aR1 axis129
Editorial: Methods in predictive toxicology 2023129
Efficacy and safety of Abelmoschus moschatus capsules combined with tripterygium glycoside tablets on diabetic nephropathy: A systematic review and meta-analysis128
Corrigendum: Shu-Xie decoction alleviates oxidative stress and colon injury in acute sleep-deprived mice by suppressing p62/KEAP1/NRF2/HO1/NQO1 signaling126
Integrating single-cell RNA-seq, bulk RNA-seq and network pharmacology reveals protective effect of salidroside in peritoneal dialysis-associated peritoneal fibrosis122
Plasma calcitonin gene-related peptide and nitric oxide predict therapeutic response to amlodipine in pediatric primary hypertension122
Associations between ionomic profile and metabolic abnormalities in a murine model of sodium sulfide induced alopecia areata121
Safety evaluation of medroxyprogesterone acetate: a pharmacovigilance analysis using FDA adverse event reporting system data119
Strategies for salvage therapy post CAR-T therapy failure in refractory/relapsed multiple myeloma patients119
Nodosin Exerts an Anti-Colorectal Cancer Effect by Inhibiting Proliferation and Triggering Complex Cell Death in Vitro and in Vivo118
Differences in right ventricular function and response to targeted therapy between patients with IPAH and PAH-CHD117
Long-term administration of bumetanide improve functional recovery after spinal cord injury in rats117
Role of ferroptosis in atrial fibrillation: a review114
Editorial: Autoimmune and Inflammatory Rheumatic Diseases: Identifying Biomarkers of Response to Therapy With Biologics113
Editorial: Utilizing omics strategies to discover new drug targets for cancers113
The efficacy of aminosalicylates in acute radiation enteritis: a systematic review and meta-analysis112
Effect of Fu Zheng Jie Du Formula on outcomes in patients with severe pneumonia receiving prone ventilation: a retrospective cohort study111
The functional significance of vascular DNA hypermethylation in atherosclerosis: a historical perspective109
Potential efficacy and mechanisms of icariin for the animal model of osteonecrosis of the femoral head109
CDFA: Calibrated deep feature aggregation for screening synergistic drug combinations107
Does preterm birth increase the initiation of antidepressant use during the postpartum? A population-based investigation103
Chemical synthesis of a reported p47phox/p22phox inhibitor and characterization of its instability and irreproducible activity102
Case Report: Rhabdomyolysis secondary to vildagliptin overdose in a suicidal attempt: A case report and brief literature review97
Potential mechanisms of Lian-Zhi-Fan solution for TNBS-induced ulcerative colitis in rats via a metabolomics approach97
Naoxintong capsule for treating cardiovascular and cerebrovascular diseases: from bench to bedside96
Interleukin 22 and its association with neurodegenerative disease activity96
Development of a vaccine against the synthetic opioid U-4770094
Association between antihypertensive drugs and oral cancer: a drug target Mendelian randomization study94
Anticancer effects of OSW-1 on glioma cells via regulation of the PI3K/AKT signal pathway: A network pharmacology approach and experimental validation in vitro and in vivo94
Investigation of anti-depression effects and potential mechanisms of the ethyl acetate extract of Cynomorium songaricum Rupr. through the integration of in vivo experiments, LC-MS/MS chemical analysis93
Research hotspots and trend analysis of cell transplantation in traumatic spinal cord injury: a bibliometric and visualized analysis93
Survival analysis of a 16-year cohort of follicular lymphoma patients receiving systemic treatment in Brazil92
Wenshen-Jianpi prescription, a Chinese herbal medicine, improves visceral hypersensitivity in a rat model of IBS-D by regulating the MEK/ERK signal pathway92
Editorial: Women in nanomedicine90
Patient-Patient Similarity-Based Screening of a Clinical Data Warehouse to Support Ciliopathy Diagnosis89
Identification of highly effective inhibitors against SARS-CoV-2 main protease: From virtual screening to in vitro study89
Healthcare professional perspectives on medication challenges in the post-stroke patient89
Dioscin Reduces Vascular Damage in the Retina of db/db Mice by Inhibiting the VEGFA Signaling Pathway88
The essential role of YAP in ERα36-mediated proliferation and the epithelial-mesenchymal transition in MCF-7 breast cancer cells88
The Protective Effects of Lipid-Lowering Agents on Cardiovascular Disease and Mortality in Maintenance Dialysis Patients: Propensity Score Analysis of a Population-Based Cohort Study88
Potential Treat-to-Target Approach for Methamphetamine Use Disorder: A Pilot Study of Adenosine 2A Receptor Antagonist With Positron Emission Tomography88
Comparison of pharmacokinetics and safety between CE-fosphenytoin sodium, fosphenytoin sodium, and phenytoin sodium after intravenous and intramuscular administration in healthy volunteers87
Corrigendum: Editorial: The mechanisms of action of anti-SARS-CoV-2 drugs87
Improvement of solubility, dissolution, and bioavailability of phenytoin intercalated in Mg-Al layered double hydroxide85
Traditional Chinese Medicine formula Dai-Zong-Fang alleviating hepatic steatosis in db/db mice via gut microbiota modulation85
Identification of potential quality markers of Zishen Yutai pill based on spectrum–effect relationship analysis85
Investigating the therapeutic potential of hesperidin targeting CRISP2 in intervertebral disc degeneration and cancer risk mitigation84
Editorial: Leukocyte biology and muscle pathology: Leukocytes as potential targets to control muscle inflammation, mass, and pain84
Bibliometric and visualized analysis of sodium–Glucose cotransporter 2 inhibitors84
Editorial: Evolution of phytochemicals and phytotherapies in the treatment and management of cancer: targeted strategies in cancer precision medicine84
Drug-drug interactions between antithrombotics and direct-acting antivirals in hepatitis C virus (HCV) patients: A brief, updated report83
Comparative study of the effects of the three kinds of Kampo-hozai: Ninjinyoeito, Hochuekkito, and Juzentaihoto on anxious and low sociability behavior using NPY-knockout zebrafish82
The role of l-leucovorin uptake and metabolism in the modulation of 5-fluorouracil efficacy and antifolate toxicity82
Non-aromatizable androgens modulate the lipopolysaccharide induced expression of the P2X7 receptor in human adipocytes81
Inhibitory effects of calcium channel blockers nisoldipine and nimodipine on ivacaftor metabolism and their underlying mechanism81
Editorial: Genomic discoveries and pharmaceutical development in urologic tumors80
Consideration in Randomized Placebo-Controlled Trial on Neck Pain to Avoid the Placebo Effect in Analgesic Action80
Cost-utility analysis of using paliperidone palmitate in schizophrenia in China79
Retraction: CXCL6 promotes renal interstitial fibrosis in diabetic nephropathy by activating JAK/STAT3 signaling pathway78
Significance of LRFN4 in prognosis and tumor microenvironment of lung adenocarcinoma78
Preventive beneficial effects of cannabidiol in a reserpine-induced progressive model of parkinsonism78
Metabolic Profiling Analysis of the Effect and Mechanism of Gushiling Capsule in Rabbits With Glucocorticoid-Induced Osteonecrosis of the Femoral Head77
Editorial: Advances on targeted nanomedicines for atherosclerosis76
Pterostilbene mitigates experimental pulmonary arterial hypertension by inhibiting endothelial-to-mesenchymal transition76
Erratum: Exploring the pharmacological action mechanism of Ligusticum Chuanxiong-Piper Longum couplet medicines on the treatment of migraine based on network pharmacology75
Influence of the ABCB1-rs1045642 gene polymorphism on blood drug concentration in voriconazole-treated patients with severe invasive fungal infection75
Pharmacist-Urologist Collaborative Management Improves Clinical Outcomes in Patients With Castration-Resistant Prostate Cancer Receiving Enzalutamide75
The Amazonian kambô frog Phyllomedusa bicolor (Amphibia: Phyllomedusidae): Current knowledge on biology, phylogeography, toxinology, ethnopharmacology and medical aspects74
Evaluation of variable new antigen receptors (vNARs) as a novel cathepsin S (CTSS) targeting strategy73
Effect of Combined Perftoran and Indocyanine Green-Photodynamic Therapy on HypoxamiRs and OncomiRs in Lung Cancer Cells73
Predicting individual-specific cardiotoxicity responses induced by tyrosine kinase inhibitors73
Case Report: Neurofilament light chain in the follow up of progressive multifocal leukoencephalopathy in a patient with multiple sclerosis treated with ocrelizumab73
Profile of STING agonist and inhibitor research: a bibliometric analysis73
A retrospective analysis of factors associated with the length of hospital stay in COVID-19 patients treated with Nirmatrelvir / Ritonavir73
Diallyl Trisulfide Enhances the Survival of Multiterritory Perforator Skin Flaps72
Transcriptome analysis revealed the genes and major pathways involved in prunetrin treated hepatocellular carcinoma cells72
Correction: The antipsychotics functional index (AFI) in schizophrenia71
Inhibition of retinal neovascularization by Dendrobium polysaccharides: a review71
Androgen receptor inhibitor ameliorates pulmonary arterial hypertension by enhancing the apoptosis level through suppressing the Notch3/Hes5 pathway70
Gastrointestinal injury in cardiopulmonary bypass: current insights and future directions70
Long-Term Cardiac Damage Associated With Abdominal Irradiation in Mice70
Cymensifin A: a promising pharmaceutical candidate to defeat lung cancer via cellular reactive oxygen species-mediated apoptosis70
Chrysophanol promotes M2 polarization and inhibits M1 polarization through the NF-κB signaling pathway to attenuate sepsis-associated acute kidney injury70
Corrigendum: Comparison of the effectiveness and safety of perampanel and oxcarbazepine as monotherapy in children and adolescents with newly diagnosed focal epilepsy69
Hemoglobin α-derived peptides VD-hemopressin (α) and RVD-hemopressin (α) are involved in electroacupuncture inhibition of chronic pain69
Development and therapeutic evaluation of 5D3(CC-MLN8237)3.2 antibody-theranostic conjugates for PSMA-positive prostate cancer therapy69
A Multicenter Study of 239 Patients Aged Over 70 Years With Diffuse Large B-Cell Lymphoma in China69
The synergistic activity of SBC3 in combination with Ebselen against Escherichia coli infection69
A nano-preparation approach to enable the delivery of daphnoretin to potentiate the therapeutical efficacy in hepatocellular cancer69
Dachengqi decoction for the treatment of acute pancreatitis: a comprehensive analysis based on metabolites, pharmacokinetics, and metabolites efficacy mechanisms69
Astragaloside IV Alleviates Intestinal Barrier Dysfunction via the AKT-GSK3β-β-Catenin Pathway in Peritoneal Dialysis69
Case report: Dezocine’s rapid and sustained antidepressant effects69
New use of an old drug: mechanism of oseltamivir phosphate inhibiting liver cancer through regulation of lipophagy via NEU169
Unveiling the hidden risk of caspofungin: insights from three adverse event reporting systems and network pharmacology integration68
Effect of age and ICU types on mortality in invasive mechanically ventilated patients with sepsis receiving dexmedetomidine: a retrospective cohort study with propensity score matching68
Economic impact of individualized antimicrobial dose optimization in the critically ill patient in Spain68
Menisoxoisoaporphine A, a novel oxoisoaporphine alkaloid from Menispermi Rhizoma, inhibits inflammation by targeting PDE4B68
Adverse events in different administration routes of amiodarone: a pharmacovigilance study based on the FDA adverse event reporting system68
Effects of public reporting of prescription indicators on patient choices: evidence from propensity scores matching68
The clinically applied PARP inhibitor talazoparib ameliorates imiquimod-induced psoriasis in mice without reducing skin inflammation68
Cardiovascular toxicities associated with chimeric antigen receptor T-cell therapy67
Natural products in treating diabetic kidney disease: a visualized bibliometric analysis67
Comparative long-term outcomes of first-line CDK4/6 inhibitors plus endocrine therapy versus endocrine therapy in patients with HR+/HER2-metastatic or advanced breast cancer: a meta-analysis67
Male mice treated with combined anti-fibrotic therapeutics, IPW5371 and tadalafil, are predisposed to adverse cardiovascular events67
Innovative strategies for post-stroke depression: integrating traditional Chinese medicine with neurobiological insights, including the gut-brain axis67
Research Progress of RNA Methylation Modification in Colorectal Cancer66
The clinical value of screening for acetaminophen in all patients with intentional overdose or altered mental status suspected to be secondary to overdose66
Multi-omic analysis reveals that Bacillus licheniformis enhances pekin ducks growth performance via lipid metabolism regulation66
Pharmacogenetic and pharmacokinetic factors for dexmedetomidine-associated hemodynamic instability in pediatric patients66
Opportunities and challenges in the treatment of IgA nephropathy65
Methotrexate-conjugated zinc oxide nanoparticles exert a substantially improved cytotoxic effect on lung cancer cells by inducing apoptosis65
Impact of roxadustat on anemia management in infected patients undergoing long-term dialysis: a retrospective cohort analysis65
Beta-blocker exposure and survival outcomes in patients with advanced pancreatic ductal adenocarcinoma: a retrospective cohort study (BETAPANC)65
Integration of meta-analysis and network pharmacology analysis to investigate the pharmacological mechanisms of traditional Chinese medicine in the treatment of hepatocellular carcinoma64
Circadian Pharmacological Effects of Paeoniflorin on Mice With Urticaria-like Lesions64
Resibufogenin Targets the ATP1A1 Signaling Cascade to Induce G2/M Phase Arrest and Inhibit Invasion in Glioma64
Inhibitory effects of total triterpenoids isolated from the Hedyotis diffusa willd on H1975 cells64
Clinical study of ganshuang granule combined with tenofovir in the treatment of chronic hepatitis B complicated with nonalcoholic fatty liver disease64
Bibliometric analysis of research on retinoic acid in the field of kidney disorders63
Plant Source Derived Compound Exhibited In Silico Inhibition of Membrane Glycoprotein In SARS-CoV-2: Paving the Way to Discover a New Class of Compound For Treatment of COVID-1963
Efficacy and safety of oral minoxidil in the treatment of alopecia: a single-arm rate meta-analysis and systematic review63
Modulating mitochondria with natural extract compounds: from bench to clinical therapeutic opportunities for COPD63
Tripterygium wilfordii glycosides ameliorates collagen-induced arthritis and aberrant lipid metabolism in rats63
Typing characteristics of metabolism-related genes in osteoporosis62
Integrated chemometric evaluation of morphological traits, chemical composition, and hepatotoxicity of Polygonum multiflorum62
Comparative efficacy and acceptability of pharmacotherapies for postpartum depression: A systematic review and network meta-analysis62
A Betulinic Acid Derivative, BA5, Induces G0/G1 Cell Arrest, Apoptosis Like-Death, and Morphological Alterations in Leishmania sp62
Discovery of a novel natural compound, vitekwangin B, with ANO1 protein reduction properties and anticancer potential62
Kinin B1R Activation Induces Endoplasmic Reticulum Stress in Primary Hypothalamic Neurons62
Application of artificial intelligence large language models in drug target discovery61
Dihydroarteannuin Ameliorates Collagen-Induced Arthritis Via Inhibiting B Cell Activation by Activating the FcγRIIb/Lyn/SHP-1 Pathway61
Screening of Microbial Natural Products and Biological Evaluation of Trichomicin as Potential Anti-Cytokine Storm Agents61
Managing novel therapies and concomitant medications in chronic lymphocytic leukemia: key challenges61
mPEG-PDLLA Micelles Potentiate Docetaxel for Intraperitoneal Chemotherapy in Ovarian Cancer Peritoneal Metastasis60
Extracellular vesicles mediate biological information delivery: A double-edged sword in cardiac remodeling after myocardial infarction60
Dexmedetomidine inhibits abnormal muscle hypertrophy of myofascial trigger points via TNF-α/ NF-κB signaling pathway in rats60
Title: Understanding a Low Vitamin D State in the Context of COVID-1960
Reynoutria japonica Houtt for Acute Respiratory Tract Infections in Adults and Children: A Systematic Review60
An overview of mechanisms, biomarkers, and treatment strategies for acquired anti-EGFR resistance in RAS wild-type colorectal cancer60
Effects of long-term antipsychotic medication on brain instability in first-episode schizophrenia patients: a resting-state fMRI study60
Enhancing therapeutic antibody profiling: orthogonal strategies for stability and quality assessment59
Optimization of gabapentin dosage in pediatric patients with renal impairment: a physiologically based pharmacokinetic modeling approach59
Function-Wise Dual-Omics analysis for radiation pneumonitis prediction in lung cancer patients59
Exploiting the anti-fibrotic effects of statins on thoracic aortic aneurysm progression: results from a meta-analysis and experimental data59
Neuroregeneration of injured peripheral nerve by fraction B of catfish epidermal secretions through the reversal of the apoptotic pathway and DNA damage59
Ginsenoside Rb1 improves intestinal aging via regulating the expression of sirtuins in the intestinal epithelium and modulating the gut microbiota of mice58
Computational and experimental pharmacology to decode the efficacy of Theobroma cacao L. against doxorubicin-induced organ toxicity in EAC-mediated solid tumor-induced mice58
In vivo pharmacokinetics of Glycyrrhiza uralensis polysaccharides58
Editorial: Pharmacogenetics and pharmacogenomics in Latin America: ethnic variability, new insights in advances and perspectives: a RELIVAF-CYTED initiative, Volume II58
Challenges in Treating Genodermatoses: New Therapies at the Horizon58
Microbiome Analysis and Pharmacovigilance After Inhaled Glucocorticoid: Oral Dysbiosis With the Isolation of Three Rothia Species and Subsequent Sjögren’s Syndrome58
Lymphatic Valve Dysfunction in Western Diet-Fed Mice: New Insights Into Obesity-Induced Lymphedema58
Dynamic risk stratification and treatment optimization in sepsis: the role of NLPR58
Traditional Chinese Medicine: A Class of Potentially Reliable Epigenetic Drugs58
Isatin improves oligoasthenospermia caused by busulfan by regulating GSH/GPX4 axis to inhibit ferroptosis58
Effects of Dexmedetomidine on Immune Cells: A Narrative Review57
The Function of Natural Polysaccharides in the Treatment of Ulcerative Colitis57
Berberine Facilitates Extinction and Prevents the Return of Fear57
Assessment of Fasudil on Contrast-Associated Acute Kidney Injury Using Multiparametric Renal MRI57
Escitalopram oxalate-loaded chitosan nanoparticle in situ gel formulation intended for direct nose-to-brain delivery: in vitro, ex vivo, and in vivo pharmacokinetic evaluation57
Z1456467176 alleviates gouty arthritis by allosterically modulating P2X7R to inhibit NLRP3 inflammasome activation57
Icotinib derivatives as tyrosine kinase inhibitors with anti-esophageal squamous carcinoma activity57
Advancing the use of real world evidence in health technology assessment: insights from a multi-stakeholder workshop56
Emerging Nanotheranostics for 5-Fluorouracil in Cancer Therapy: A Systematic Review on Efficacy, Safety, and Diagnostic Capability56
Integrated network pharmacology and experimental analysis unveil multi-targeted effect of 18α- glycyrrhetinic acid against non-small cell lung cancer56
Traditional Chinese medicine in the prevention of diabetes mellitus and cardiovascular complications: mechanisms and therapeutic approaches56
Case Report: Botulism associated with cosmetic BoNT-A injections: respiratory failure and multidrug-resistant infection as emerging clinical challenges56
SARS-CoV-2 infection dysregulates the expression of clinically relevant drug metabolizing enzymes in Vero E6 cells and membrane transporters in human lung tissues56
Pterostilbene in Combination With Mitochondrial Cofactors Improve Mitochondrial Function in Cellular Models of Mitochondrial Diseases56
Centella asiatica Alters Metabolic Pathways Associated With Alzheimer’s Disease in the 5xFAD Mouse Model of ß-Amyloid Accumulation56
Immune Effect of Active Components of Traditional Chinese Medicine on Triple-Negative Breast Cancer56
Hermansky-Pudlak Syndrome: Identification of Novel Variants in the Genes HPS3, HPS5, and DTNBP1 (HPS-7)56
Editorial: Big data for biomedical research of inflammatory diseases56
Protective effects of insulin on dry eye syndrome via TLR4/NF-κB pathway: based on network pharmacology and in vitro experiments validation55
Comprehensive Analysis of Chemical Structures That Have Been Tested as CFTR Activating Substances in a Publicly Available Database CandActCFTR55
Editorial: Dissecting Traditional Medicine via Chemical and Biochemical Techniques: Advanced Analytics and Novel Paradigms55
Efficacy and safety of sequential immunosuppressive treatment for severe IgA nephropathy: A retrospective study55
In vitro effect of hydroxychloroquine on pluripotent stem cells and their cardiomyocytes derivatives55
Population pharmacokinetics and dosing optimization of unbound teicoplanin in Chinese adult patients55
Which is the optimal choice in lipid-lowering therapy for reducing major cardiovascular events? a network meta-analysis55
Myristic acid beneficially modulates intervertebral disc degeneration by preventing endplate osteochondral remodeling and vertebral osteoporosis in naturally aged mice55
Corrigendum: Sanguisorba officinalis L. Suppresses Triple-Negative Breast Cancer Metastasis by Inhibiting Late-Phase Autophagy via Hif-1α/Caveolin-1 Signaling55
Network pharmacology-based and experimental identification of the effects of Renshen Yangrong decoction on myocardial infarction55
The macrocyclic lactone oxacyclododecindione reduces fibrosis progression54
Tailoring second-line or above therapy for patients with advanced or metastatic gastric cancer: A multicenter real-world study54
Chronic Administration of COVID-19 Drugs Fluvoxamine and Lopinavir Shortens Action Potential Duration by Inhibiting the Human Ether‐à‐go‐go–Related Gene and Cav1.254
Transcriptome analysis revealed the role of mTOR and MAPK signaling pathways in the white strain of Hypsizygus marmoreus extracts-induced cell death of human hepatoma Hep3B cells54
Cost-effectiveness of empagliflozin for the treatment of heart failure: a systematic review54
The Transcultural Adaptation and Validation of the Chinese Version of the Duke Anticoagulation Satisfaction Scale54
Overview of Cannabis including Kampo Medicine and Therapy for Treatment of Dementia: A Review54
Wendan decoction in the treatment of nonalcoholic fatty liver disease: A systematic review and meta-analysis54
A New Strategy for Multitarget Drug Discovery/Repositioning Through the Identification of Similar 3D Amino Acid Patterns Among Proteins Structures: The Case of Tafluprost and its Effects on Cardiac Io54
Functional effects of drugs and toxins interacting with NaV1.453
Editorial: Streaming inflammation: From damage to healing and resilience–Volume II53
Qishen Granule (QSG) Inhibits Monocytes Released From the Spleen and Protect Myocardial Function via the TLR4-MyD88-NF-κB p65 Pathway in Heart Failure Mice53
A minimal PBPK model to accelerate preclinical development of drugs against tuberculosis53
ALG-bFGF Hydrogel Inhibiting Autophagy Contributes to Protection of Blood–Spinal Cord Barrier Integrity via PI3K/Akt/FOXO1/KLF4 Pathway After SCI53
Polygala tenuifolia and Acorus tatarinowii in the treatment of Alzheimer’s disease: a systematic review and meta-analysis53
Factors influencing plasma concentration of voriconazole and voriconazole- N-oxide in younger adult and elderly patients53
Inhibition of PPARγ by BZ26, a GW9662 derivate, attenuated obesity-related breast cancer progression by inhibiting the reprogramming of mature adipocytes into to cancer associate adipocyte-like cells52
Prediction of Immune-Related Adverse Events Induced by Immune Checkpoint Inhibitors With a Panel of Autoantibodies: Protocol of a Multicenter, Prospective, Observational Cohort Study52
Buyang Huanwu Decoction alleviates cerebral ischemic injury through modulating caveolin-1-mediated mitochondrial quality control52
Mechanistic study on the restoration of intestinal barrier integrity and alleviation of inflammatory bowel disease by rhynchophylline via the AhR-NR4A1 pathway52
Ferroptosis, pathogenesis and therapy in AS co-depression disease52
Antirheumatoid Arthritic Effects of Sabia parviflora Wall. Leaf Extracts via the NF-κB Pathway and Transient Receptor Potential Protein Family52
Xuanfei Pingchuan Capsules Ameliorate Autophagy in Human Bronchial Epithelial Cells by Inhibiting p38 Phosphorylation52
The electrocardiographic, hemodynamic, echocardiographic, and biochemical evaluation of treatment with edaravone on acute cardiac toxicity of aluminum phosphide52
A PDE10A inhibitor CPL500036 is a novel agent modulating striatal function devoid of most neuroleptic side-effects52
Oxylipins as therapeutic indicators of herbal medicines in cardiovascular diseases: a review52
Autophagy plays an essential role in ultraviolet radiation-driven skin photoaging51
In situ sustained release of icariin from injectable thermosensitive PLGA-PEG-PLGA hydrogels combined with core decompression for steroid-induced osteonecrosis of femoral head51
The volatile oil of Acorus tatarinowii schott significantly attenuates neuroinflammatory damage in a rat model of tourette syndrome by inhibiting the p38 MAPK/NLRP3/STAT3 signaling pathway51
Network pharmacology and experimental verification-based strategy to explore the underlying mechanism of Liu Jun An Wei formula in the treatment of gastrointestinal reactions caused by chemotherapy fo51
Prospective population pharmacokinetic study of tacrolimus in adult recipients early after liver transplantation: A comparison of Michaelis-Menten and theory-based pharmacokinetic models51
Factors associated with medication adherence among children with rheumatic diseases51
Post-marketing safety surveillance of dalfampridine for multiple sclerosis using FDA adverse event reporting system51
Network pharmacology and transcriptomics reveal the mechanisms of FFBZL in the treatment of oral squamous cell carcinoma51
Cost-effectiveness analysis of lenvatinib plus pembrolizumab compared with chemotherapy for patients with previously treated mismatch repair proficient advanced endometrial cancer in China51
Therapeutic Drug Monitoring of Anti-Thymocyte Globulin in Allogeneic Stem Cell Transplantation: Proof of Concept50
Natural drugs targeting inflammation pathways can be used to treat atherosclerosis50
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