Frontiers in Pharmacology

Article	Citations
Association between hyperuricemia and all-cause mortality in people taken Statins: a retrospective cohort study	569
pH-induced conformational changes in the selectivity filter of a potassium channel lead to alterations in its selectivity and permeation properties	380
GraphTransNet: predicting epilepsy-related genes using a graph-augmented protein language model	368
Quantifying the integrated physiological effects of endothelin-1 on cardiovascular and renal function in healthy subjects: a mathematical modeling analysis	339
Editorial: Chronic pain: what is the mechanism?	318
Time trends and regional variations in prices of anticancer medicines in China	317
Editorial: Impact of anesthetics on cancer behavior and outcome	310
Unlocking cellular traffic jams: olive oil-mediated rescue of CNG mutant channels	302
Impact of domiciliary administration of NSAIDs on COVID-19 hospital outcomes: an unCoVer analysis	230
Differences in right ventricular function and response to targeted therapy between patients with IPAH and PAH-CHD	226
Effect of Fu Zheng Jie Du Formula on outcomes in patients with severe pneumonia receiving prone ventilation: a retrospective cohort study	217
Potential efficacy and mechanisms of icariin for the animal model of osteonecrosis of the femoral head	209
Case Report: Rhabdomyolysis secondary to vildagliptin overdose in a suicidal attempt: A case report and brief literature review	201
Development of a vaccine against the synthetic opioid U-47700	186
Association between antihypertensive drugs and oral cancer: a drug target Mendelian randomization study	184
Research hotspots and trend analysis of cell transplantation in traumatic spinal cord injury: a bibliometric and visualized analysis	183
Editorial: Women in nanomedicine	178
Editorial: Leukocyte biology and muscle pathology: Leukocytes as potential targets to control muscle inflammation, mass, and pain	176
Comparison of pharmacokinetics and safety between CE-fosphenytoin sodium, fosphenytoin sodium, and phenytoin sodium after intravenous and intramuscular administration in healthy volunteers	176
Editorial: Evolution of phytochemicals and phytotherapies in the treatment and management of cancer: targeted strategies in cancer precision medicine	173
Drug-drug interactions between antithrombotics and direct-acting antivirals in hepatitis C virus (HCV) patients: A brief, updated report	171
Non-aromatizable androgens modulate the lipopolysaccharide induced expression of the P2X7 receptor in human adipocytes	157
Significance of LRFN4 in prognosis and tumor microenvironment of lung adenocarcinoma	153
Editorial: Advances on targeted nanomedicines for atherosclerosis	143
Influence of the ABCB1-rs1045642 gene polymorphism on blood drug concentration in voriconazole-treated patients with severe invasive fungal infection	141

A retrospective analysis of factors associated with the length of hospital stay in COVID-19 patients treated with Nirmatrelvir / Ritonavir	133
Evaluation of variable new antigen receptors (vNARs) as a novel cathepsin S (CTSS) targeting strategy	130
Androgen receptor inhibitor ameliorates pulmonary arterial hypertension by enhancing the apoptosis level through suppressing the Notch3/Hes5 pathway	128
Cymensifin A: a promising pharmaceutical candidate to defeat lung cancer via cellular reactive oxygen species-mediated apoptosis	126
Case report: Dezocine’s rapid and sustained antidepressant effects	124
A nano-preparation approach to enable the delivery of daphnoretin to potentiate the therapeutical efficacy in hepatocellular cancer	124
Menisoxoisoaporphine A, a novel oxoisoaporphine alkaloid from Menispermi Rhizoma, inhibits inflammation by targeting PDE4B	122
The clinically applied PARP inhibitor talazoparib ameliorates imiquimod-induced psoriasis in mice without reducing skin inflammation	120
Male mice treated with combined anti-fibrotic therapeutics, IPW5371 and tadalafil, are predisposed to adverse cardiovascular events	117
The clinical value of screening for acetaminophen in all patients with intentional overdose or altered mental status suspected to be secondary to overdose	115
Which is the optimal choice in lipid-lowering therapy for reducing major cardiovascular events? a network meta-analysis	114
Network pharmacology-based and experimental identification of the effects of Renshen Yangrong decoction on myocardial infarction	113
Cost-effectiveness of empagliflozin for the treatment of heart failure: a systematic review	111
Tailoring second-line or above therapy for patients with advanced or metastatic gastric cancer: A multicenter real-world study	111
The macrocyclic lactone oxacyclododecindione reduces fibrosis progression	110
Editorial: Streaming inflammation: From damage to healing and resilience–Volume II	109
Inhibition of PPARγ by BZ26, a GW9662 derivate, attenuated obesity-related breast cancer progression by inhibiting the reprogramming of mature adipocytes into to cancer associate adipocyte-like cells	107
Natural drugs targeting inflammation pathways can be used to treat atherosclerosis	107
Dopaminergic REST is implicated in the tamoxifen-induced neuroprotection against manganese toxicity in female mice	106
Editorial: Genomic discoveries and pharmaceutical development in urologic tumors	106
Commentary: Iridoids derived from Valeriana jatamansi jones alleviates neuroinflammation and blood spinal cord barrier permeability after spinal cord injury by activating the Nrf2/HO-1 signaling pathw	106
Cytotoxicity and reversal effect of sertraline, fluoxetine, and citalopram on MRP1- and MRP7-mediated MDR	106
Integrated chemometric evaluation of morphological traits, chemical composition, and hepatotoxicity of Polygonum multiflorum	104
Optimization of gabapentin dosage in pediatric patients with renal impairment: a physiologically based pharmacokinetic modeling approach	103
Icotinib derivatives as tyrosine kinase inhibitors with anti-esophageal squamous carcinoma activity	103
Accidental cannabis intoxication in two young children: clinical presentation and toxicokinetics - a case series	102
Ex vivo perfusion model of mouse liver and its application to analyze the effects of OCT1 deficiency	102
Interaction and potential mechanisms between atorvastatin and voriconazole, agents used to treat dyslipidemia and fungal infections	101
Evaluation of standard use of intravenous infusion in 25 general hospitals in Shanxi province based on factor analysis and cluster analysis	99
Protective effects of insulin on dry eye syndrome via TLR4/NF-κB pathway: based on network pharmacology and in vitro experiments validation	99
Safety profile of lutein-based blue dyes and surgical lights	99
Strategies for salvage therapy post CAR-T therapy failure in refractory/relapsed multiple myeloma patients	98
Editorial: Big data for biomedical research of inflammatory diseases	98
The efficacy of aminosalicylates in acute radiation enteritis: a systematic review and meta-analysis	97
Is it possible to diagnose therapeutic adherence in mild cognitive impairment and dementia patients in clinical practice?	97
Functional characterization of the α1-adrenoceptor in adult male rat locus coeruleus neurons ex vivo	96
Acute myocardial infarction induced by avatrombopag: a case report	96
Machine learning methods for propensity and disease risk score estimation in high-dimensional data: a plasmode simulation and real-world data cohort analysis	95
The Amazonian kambô frog Phyllomedusa bicolor (Amphibia: Phyllomedusidae): Current knowledge on biology, phylogeography, toxinology, ethnopharmacology and medical aspects	95
8 specific Chinese herbal injections combined with chemotherapy for breast cancer: a systematic review and network meta-analysis of comparative safety and efficacy	95
Recent clinical evidence on nutrition, novel pharmacotherapy, and vaccination in inflammatory bowel diseases	92
Efficacy, safety and mechanism of Honghua Xiaoyao Pill in the treatment of peri-menopausal syndrome: A study protocol for a randomized controlled trial	90
Barriers to prescribing and insurance approval of SGLT2 inhibitors for heart failure: a mixed-methods study in Jordan	90
Investigating the therapeutic potential of hesperidin targeting CRISP2 in intervertebral disc degeneration and cancer risk mitigation	90
Integrating single-cell RNA-seq, bulk RNA-seq and network pharmacology reveals protective effect of salidroside in peritoneal dialysis-associated peritoneal fibrosis	89
Doxycycline for the treatment of breast cancer-related lymphedema	89
A machine learning model integrating gut microbiota biomarkers for predicting neurological recovery after cerebral hypoxia-ischemia: a single-center study augmented with public data	89
Targeting cancer with delphinidin: from molecular insights to therapeutic implications	88
Wendan decoction in the treatment of nonalcoholic fatty liver disease: A systematic review and meta-analysis	88
SARS-CoV-2 infection dysregulates the expression of clinically relevant drug metabolizing enzymes in Vero E6 cells and membrane transporters in human lung tissues	87

Correction: Efficacy and safety of oral Chinese medicine combined with chemotherapy: a systematic review and network meta-analysis	87
Potential mechanisms of Lian-Zhi-Fan solution for TNBS-induced ulcerative colitis in rats via a metabolomics approach	85
A minimal PBPK model to accelerate preclinical development of drugs against tuberculosis	85
Sishen Pill and its active phytochemicals in treating inflammatory bowel disease and colon cancer: an overview	85
Does preterm birth increase the initiation of antidepressant use during the postpartum? A population-based investigation	85
Ivarmacitinib reduces the need for adding/escalating medications in moderate-to-severe rheumatoid arthritis patients: a post hoc analysis from a phase III trial	85
Clinical study of ganshuang granule combined with tenofovir in the treatment of chronic hepatitis B complicated with nonalcoholic fatty liver disease	84
Biomimetic astragaloside-IV-loaded mesoporous silica nanoparticles for treatment of dilated cardiomyopathy	84
Effect of age and ICU types on mortality in invasive mechanically ventilated patients with sepsis receiving dexmedetomidine: a retrospective cohort study with propensity score matching	84
Exploring the mechanism of baicalein on choroid melanoma based on network pharmacology, transcriptomics and experimental verification	84
Chaihu Longgu Muli Decoction inhibits chronic stress-induced lung cancer epithelial-mesenchymal transition process by suppressing Rap1/ERK signal pathway	83
Case Report: Botulism associated with cosmetic BoNT-A injections: respiratory failure and multidrug-resistant infection as emerging clinical challenges	83
Exploring HSP90α and hs-CRP using AI models to predict prognosis in advanced hepatocellular carcinoma treated with PD-1 inhibitors and targeted therapy	83
Chinese herbal compound for multidrug-resistant or extensively drug-resistant bacterial pneumonia: a meta-analysis and trial sequential analysis with association rule mining to identify core herb comb	83
First-in-human study to assess the safety, tolerability, pharmacokinetics and immunogenicity of DS002, an anti-nerve growth factor monoclonal antibody	82
Editorial: Metabolic dysfunction-associated fatty liver disease (MAFLD): innovative management strategies using herbal medicines	81
Genome-wide CRISPR screen identified NEK6 as a determinant of sensitivity to CDK4/6 inhibitor in endometrial cancer	81
Preventive effect of small molecule active substances on septic cardiomyopathy after abdominal trauma: a systematic review and meta-analysis	81
Natural product extracts for ischemic stroke: a methodological evaluation and meta-epidemiological analysis	81
Correction: The antipsychotics functional index (AFI) in schizophrenia	80
Corrigendum: Comparison of the effectiveness and safety of perampanel and oxcarbazepine as monotherapy in children and adolescents with newly diagnosed focal epilepsy	79
Corrigendum: Shu-Xie decoction alleviates oxidative stress and colon injury in acute sleep-deprived mice by suppressing p62/KEAP1/NRF2/HO1/NQO1 signaling	78
Inhibitory effects of calcium channel blockers nisoldipine and nimodipine on ivacaftor metabolism and their underlying mechanism	78
Corrigendum: Xenon attenuated neonatal lipopolysaccharide exposure induced neuronal necroptosis and subsequently improved cognition in juvenile rats	77
Erratum: Isoflurane-lipid emulsion injection as an anticonvulsant and neuroprotectant treatment for nerve agent exposure	77
Erratum: Exploring the pharmacological action mechanism of Ligusticum Chuanxiong-Piper Longum couplet medicines on the treatment of migraine based on network pharmacology	77
Corrigendum: Editorial: The mechanisms of action of anti-SARS-CoV-2 drugs	77
Efficacy analysis of splint combined with platelet-rich plasma in the treatment of temporomandibular joint osteoarthritis	76
Wenshen-Jianpi prescription, a Chinese herbal medicine, improves visceral hypersensitivity in a rat model of IBS-D by regulating the MEK/ERK signal pathway	76
Pemetrexed sensitizes cisplatin therapy by inducing ferroptosis in NSCLC cells	76
Drug-related problems among transfusion-dependent thalassemia patients: A real-world evidence study	76
Radiosensitization effect of iridium (III) complex on lung cancer cells via mitochondria apoptosis pathway	75
Buyang Huanwu Decoction alleviates cerebral ischemic injury through modulating caveolin-1-mediated mitochondrial quality control	75
Effect of corticosteroids combined with cyclophosphamide or mycophenolate mofetil therapy for IgA nephropathy with stage 3 or 4 chronic kidney disease: A retrospective cohort study	75
Long-term administration of bumetanide improve functional recovery after spinal cord injury in rats	74
Natural killer cell-related prognosis signature predicts immune response in colon cancer patients	74
Evaluation of trimetazidine in alleviating paclitaxel-induced peripheral neuropathy in breast cancer patients: a randomized controlled trial	74
Modulating mitochondria with natural extract compounds: from bench to clinical therapeutic opportunities for COPD	74
Identification of potential quality markers of Zishen Yutai pill based on spectrum–effect relationship analysis	74
Discovery of a novel natural compound, vitekwangin B, with ANO1 protein reduction properties and anticancer potential	74
Gegen Qinlian decoction prevents post-ERCP pancreatitis by regulating NLRP3 inflammasome-mediated pyroptosis	73
Nephroprotective potential of Polyalthia longifolia roots against vancomycin-induced renal toxicity in experimental animals	73
Z1456467176 alleviates gouty arthritis by allosterically modulating P2X7R to inhibit NLRP3 inflammasome activation	72
Efficacy and safety of Chinese medicine injections in combination with docetaxel and cisplatin for non-small cell lung cancer: a network meta-analysis	72
Efficacy and safety of Abelmoschus moschatus capsules combined with tripterygium glycoside tablets on diabetic nephropathy: A systematic review and meta-analysis	72
Using Drosophila melanogaster as a suitable platform for drug discovery from natural products in inflammatory bowel disease	72
The forensic aspects of suicide and neurotrophin factors: a research study	72
Traditional Chinese Medicine in Treating Primary Podocytosis: From Fundamental Science to Clinical Research	71
Multi-omic analysis reveals that Bacillus licheniformis enhances pekin ducks growth performance via lipid metabolism regulation	71
Individualized, dynamic, and full-course vancomycin dosing prediction: a study on the customized dose model	71
Strategy advancements in placental pharmacokinetics: from in vitro experiments to in silico prediction	69
Frankincense preparation promotes formation of inflammation-resolving lipid mediators by manipulating lipoxygenases in human innate immune cells	69
Ninjin’yoeito ameliorated PPE-induced pulmonary emphysema and anxiety/depressive-like behavior in aged C57BL/6J mice	69
Challenges in melanoma research and increased melanoma risk call for novel methodological and therapeutic/protective strategies: the case of procyanidin C1 targeting redox metabolism	68
Research progress on high-altitude hypoxia pulmonary injury: pathogenesis and Chinese herbal medicine for prevention and treatment	68
Ebracteolata cpd B causes ferroptosis and inhibits progression of lung adenocarcinoma	68
Anticancer effects of OSW-1 on glioma cells via regulation of the PI3K/AKT signal pathway: A network pharmacology approach and experimental validation in vitro and in vivo	68
Population pharmacokinetics and dosing optimization of unbound teicoplanin in Chinese adult patients	68
Evaluation of the efficacy, safety, and economy of nemonoxacin injection versus moxifloxacin injection in the treatment of community-acquired pneumonia	68
Editorial: Pharmacogenetics and pharmacogenomics in Latin America: ethnic variability, new insights in advances and perspectives: a RELIVAF-CYTED initiative, Volume II	68
Predicting individual-specific cardiotoxicity responses induced by tyrosine kinase inhibitors	67
Network pharmacology and transcriptomics reveal the mechanisms of FFBZL in the treatment of oral squamous cell carcinoma	67
Farrerol inhibits proliferation and migration of colorectal cancer via the VEGF signaling pathway: evidence from network pharmacology, molecular docking, molecular dynamics simulation, and in vitro ex	67
Retraction: CXCL6 promotes renal interstitial fibrosis in diabetic nephropathy by activating JAK/STAT3 signaling pathway	67
Xanthine oxidase inhibition by medicinal plants mitigates tenofovir-induced nephrotoxicity: a comprehensive computational and experimental study	67
Computational and experimental pharmacology to decode the efficacy of Theobroma cacao L. against doxorubicin-induced organ toxicity in EAC-mediated solid tumor-induced mice	67
Functional effects of drugs and toxins interacting with NaV1.4	67
New use of an old drug: mechanism of oseltamivir phosphate inhibiting liver cancer through regulation of lipophagy via NEU1	66
Gut microbiota–M cell co-culture in inflammatory bowel disease and its therapeutic potential in organoid platforms	66
Pharmacogenomic-guided dosing of fluoropyrimidines beyond DPYD: time for a polygenic algorithm?	66
Enhancing therapeutic antibody profiling: orthogonal strategies for stability and quality assessment	66
The therapeutic potential of Vanilla planifolia: how its phytochemicals combat diabetes?	66
Dexmedetomidine attenuates Alzheimer’s pathogenesis by targeting the ROS-mediated XIAP-MDM2-p53 signaling axis	66
Improvement of solubility, dissolution, and bioavailability of phenytoin intercalated in Mg-Al layered double hydroxide	65
The volatile oil of Acorus tatarinowii schott significantly attenuates neuroinflammatory damage in a rat model of tourette syndrome by inhibiting the p38 MAPK/NLRP3/STAT3 signaling pathway	65
Pterostilbene mitigates experimental pulmonary arterial hypertension by inhibiting endothelial-to-mesenchymal transition	65
Indirect effect of alpha-1-antitrypsin on endotoxin-induced IL-1β secretion from human PBMCs	65
Serum metabolomics identifies novel prognostic biomarkers in amanita poisoning	65
Oxylipins as therapeutic indicators of herbal medicines in cardiovascular diseases: a review	65
Correction: Safety and efficacy of tirzepatide in transplant recipients: a systematic review and meta-analysis	65

Myristic acid beneficially modulates intervertebral disc degeneration by preventing endplate osteochondral remodeling and vertebral osteoporosis in naturally aged mice	64
Multitarget mechanisms of the herb pair Achyranthes bidentata and Paeonia lactiflora Pall. in ameliorating hypertensive cardiomyopathy: combining network pharmacology and functional exploration	64
Pichia pastoris secreted peptides crossing the blood-brain barrier and DSIP fusion peptide efficacy in PCPA-induced insomnia mouse models	64
Chrysophanol promotes M2 polarization and inhibits M1 polarization through the NF-κB signaling pathway to attenuate sepsis-associated acute kidney injury	64
Ginsenosides, potential TMPRSS2 inhibitors, a trade-off between the therapeutic combination for anti-PD-1 immunotherapy and the treatment of COVID-19 infection of LUAD patients	64
Evaluating a multifaceted stewardship intervention on proton pump inhibitor utilization: an interrupted time-series analysis of prescribing patterns in a northwest Chinese hospital	64
Icariin and related metabolites in fibrosis management: pharmacological properties and molecular mechanism	64
Metabolite-assisted models improve risk prediction of coronary heart disease in patients with diabetes	63
IR-780 improves urination function and complications in rats with partial bladder outlet obstruction by protecting bladder smooth muscle cell mitochondria from oxidative stress	63
Several major herb pairs containing Coptidis rhizoma: a review of key traditional uses, constituents and compatibility effects	63
Pharmacogenomics of risperidone in autism spectrum disorder: a minireview	63
Healthcare professional perspectives on medication challenges in the post-stroke patient	63
Correction: Editorial: Toxicity mechanisms, exposure, toxicokinetic and risk assessment aspects of metals, toxic for animals and humans, volume III	63
Editorial: Therapeutic drug monitoring (TDM): a useful tool for pediatric pharmacology applied to routine clinical practice, Volume II	63
Editorial: Oral mucosa and disorders: from drug discovery to development and translation	63
The synergistic activity of SBC3 in combination with Ebselen against Escherichia coli infection	62
Therapeutic drug monitoring practices of anti-infectives: An Asia-wide cross-sectional survey	62
Factors influencing plasma concentration of voriconazole and voriconazole- N-oxide in younger adult and elderly patients	62
Transcriptome analysis revealed the role of mTOR and MAPK signaling pathways in the white strain of Hypsizygus marmoreus extracts-induced cell death of human hepatoma Hep3B cells	62
Plasma calcitonin gene-related peptide and nitric oxide predict therapeutic response to amlodipine in pediatric primary hypertension	62
Genetic characterization of pediatric B-cell acute lymphoblastic leukemia in Argentina uncovers molecular heterogeneity and novel variants	61
Investigation of anti-depression effects and potential mechanisms of the ethyl acetate extract of Cynomorium songaricum Rupr. through the integration of in vivo experiments, LC-MS/MS chemical analysis	61
The categorizations of vasculogenic mimicry in clear cell renal cell carcinoma unveil inherent connections with clinical and immune features	61
Inhibitory effects of total triterpenoids isolated from the Hedyotis diffusa willd on H1975 cells	61
Bibliometric and visualized analysis of sodium–Glucose cotransporter 2 inhibitors	61
Distinct alterations of fecal microbiota refer to the efficacy of adalimumab in Crohn’s disease	60
Advances in the study of Ophiopogon japonicus polysaccharides: structural characterization, bioactivity and gut microbiota modulation regulation	60
Prescription medication use of United States military service members by therapeutic classification	60
Real-world pharmacovigilance and molecular mechanisms of fruquintinib: SRC and STAT3 as potential off-target mediators of proteinuria	60
Naoxintong capsule for treating cardiovascular and cerebrovascular diseases: from bench to bedside	60
Effects of Broussonetia papyrifera (L.) L'Hér. ex Vent. fruits water extract on hippocampal neurogenesis in the treatment of APP/PS1 transgenic mice	60
Current situation and future development of the biopharmaceutical industry in China: A mixed-method study	59
Activation of EP4 alleviates AKI-to-CKD transition through inducing CPT2-mediated lipophagy in renal macrophages	59
Neuroprotective effect of dexmedetomidine on autophagy in mice administered intracerebroventricular injections of Aβ25–35	59
Preventive beneficial effects of cannabidiol in a reserpine-induced progressive model of parkinsonism	59
AduCPI2 alleviates MSU-induced acute gouty arthritis in mice by inhibiting cathepsin S and the C5a-C5aR1 axis	59
Editorial: Epigenetic modifications and cardiovascular diseases	59
Deutscher Arzneimittel-Codex-aligned multi-dimensional quality assessment of Gastrodiae Rhizoma granules	58
Inhibition of retinal neovascularization by Dendrobium polysaccharides: a review	58
Selective biological activity of parthenolide derivatives — stizolin, stizolicin, and izospiciformin — isolated from the leaves of Stizolophus balsamita, in different breast cancer molecular subtypes	58
Development and therapeutic evaluation of 5D3(CC-MLN8237)3.2 antibody-theranostic conjugates for PSMA-positive prostate cancer therapy	58
Leveraging AI to automate detection and quantification of extrachromosomal DNA to decode drug responses	58
Editorial: Advances in the potential treatments of gastrointestinal and liver diseases: addressing the public health burden, volume II	58
Correction: Developmental and angiogenic safety profiles of novel pyridine-based chalcone	58
Potential role of extracellular granzyme B in wet age-related macular degeneration and fuchs endothelial corneal dystrophy	58
AI-assisted literature exploration of innovative Chinese medicine formulas	57
Correction: Combined ACEI and ARB therapy and ICU mortality in critically ill COVID-19 patients: a retrospective cohort study	57
EV-associated non-coding RNAs in paediatric asthma airway remodelling: current mechanistic evidence and therapeutic perspectives	57
Typing characteristics of metabolism-related genes in osteoporosis	57
Efficacy and safety of sequential immunosuppressive treatment for severe IgA nephropathy: A retrospective study	57
A RAIR–ATC transcriptional axis and multimodal drug-response modelling reveal class-level vulnerabilities in thyroid cancer	57
Correction: Efficacy and safety of omadacycline for the treatment of infectious diseases: a real-world, retrospective study of 2587 patients	57
Comparison of remimazolam and propofol combined with low dose esketamine for pediatric same-day painless bidirectional endoscopy: a randomized, controlled clinical trial	57
HtrA2/Omi: potential therapeutic targets for neurodegenerative diseases	57
Immunogenic cell death in cold tumors: transforming immune-excluded tumors into immunotherapy-sensitive lesions	57
Evaluating cardiac disorders associated with triazole antifungal agents based on the US Food and Drug Administration Adverse Event reporting system database	56
Dachengqi decoction for the treatment of acute pancreatitis: a comprehensive analysis based on metabolites, pharmacokinetics, and metabolites efficacy mechanisms	56
D-mannose reduces oxidative stress, inhibits inflammation, and increases treg cell proportions in mice with ulcerative colitis	56
Integration of meta-analysis and network pharmacology analysis to investigate the pharmacological mechanisms of traditional Chinese medicine in the treatment of hepatocellular carcinoma	56
Methotrexate-conjugated zinc oxide nanoparticles exert a substantially improved cytotoxic effect on lung cancer cells by inducing apoptosis	56
Case report: A case of ITP-like thrombocytopenia induced by denosumab	56
In situ sustained release of icariin from injectable thermosensitive PLGA-PEG-PLGA hydrogels combined with core decompression for steroid-induced osteonecrosis of femoral head	55
Innovative strategies for post-stroke depression: integrating traditional Chinese medicine with neurobiological insights, including the gut-brain axis	55
Ferroptosis, pathogenesis and therapy in AS co-depression disease	55
Optimization of ivacaftor-loaded solid lipid nanoparticles for solubility enhancement	55
Economic impact of individualized antimicrobial dose optimization in the critically ill patient in Spain	55
Natural products from plants and microorganisms: Novel therapeutics for chronic kidney disease via gut microbiota regulation	55
Artemisitene Alters LPS-Induced Oxidative stress, inflammation and Ferroptosis in Liver Through Nrf2/HO-1 and NF-kB Pathway	55
Ophiopogonin D increase apoptosis by activating p53 via ribosomal protein L5 and L11 and inhibiting the expression of c-Myc via CNOT2	55
Quantum chemical calculations of nitrosamine activation and deactivation pathways for carcinogenicity risk assessment	55
Editorial: Plant polyphenols: new chemical and pharmacological approaches	54
Human leukocyte antigen pharmacogenetics in infectious diseases: anti-infective drug toxicity and host immune response	54
In vitro effect of hydroxychloroquine on pluripotent stem cells and their cardiomyocytes derivatives	54
Adverse events in different administration routes of amiodarone: a pharmacovigilance study based on the FDA adverse event reporting system	54
Protective effect and mechanism of Qingfei Paidu decoction on myocardial damage mediated by influenza viruses	54
Medicinal fungus Phellinus igniarius alleviates gout in vitro by modulating TLR4/NF-kB/NLRP3 signaling	54
Pre- and post-chemotherapy spermatogenesis in male patients with malignant bone and soft tissue tumors	54
Factors associated with medication adherence among children with rheumatic diseases	54
A comprehensive review of ischemic heart disease: pathophysiology, current treatments, natural products-based therapies, and nanotherapeutics	54
Ocular development after highly effective modulator treatment early in life	54
D-cycloserine effects on COPD and depression in a murine experimental model	54
Comparative efficacy of commercial Chinese polyherbal preparation for coronary microvascular dysfunction: a systematic review and network meta-analysis of randomized controlled trials	54
Effects of long-term antipsychotic medication on brain instability in first-episode schizophrenia patients: a resting-state fMRI study	53
Abhraka Bhasma (mica based nanomedicine): an ayurvedic herbomineral perspective in breast cancer management	53
The esketamine-based multimodal low-opioid anaesthesia improves quality of recovery in elderly patients undergoing radical lung cancer surgery: a randomized controlled trial	53
Beta-blocker exposure and survival outcomes in patients with advanced pancreatic ductal adenocarcinoma: a retrospective cohort study (BETAPANC)	53
Optimizing antidotal treatment with the oral HSP90 inhibitor TAS-116 against hydrochloric acid-induced pulmonary fibrosis in mice	53
Investigation of anti-nociceptive, anti-inflammatory potential and ADMET studies of pure compounds isolated from Isodon rugosus Wall. ex Benth	53
Therapeutic potential of growth hormone-releasing hormone analogues in cardiovascular and cerebrovascular diseases: mechanisms and preclinical evidence	53
Cost-effectiveness analysis of lenvatinib plus pembrolizumab compared with chemotherapy for patients with previously treated mismatch repair proficient advanced endometrial cancer in China	53
Cost-utility analysis of using paliperidone palmitate in schizophrenia in China	53
The role of NLRP3 inflammasome in hepatocellular carcinoma	53
Exploiting the anti-fibrotic effects of statins on thoracic aortic aneurysm progression: results from a meta-analysis and experimental data	53
Dicaffeoylquinic acid alleviates alcoholic liver disease by targeting PLA2G4B and inhibiting the MAPK signaling pathway	53
Chinese expert consensus on the choice of initial cholesterol-lowering strategy	53