Frontiers in Pharmacology

Article	Citations
Pre- and post-chemotherapy spermatogenesis in male patients with malignant bone and soft tissue tumors	529
Individualized, dynamic, and full-course vancomycin dosing prediction: a study on the customized dose model	365
Metabolite-assisted models improve risk prediction of coronary heart disease in patients with diabetes	321
Potential of resveratrol in the treatment of interstitial lung disease	301
Editorial: Women in nanomedicine	257
Title: Understanding a Low Vitamin D State in the Context of COVID-19	243
The forensic aspects of suicide and neurotrophin factors: a research study	229
Understanding Stakeholder Views Regarding the Design of an Intervention Trial to Reduce Anticholinergic Burden: A Qualitative Study	208
Upregulation of Phosphodiesterase 2A Augments T Cell Activation by Changing cGMP/cAMP Cross-Talk	197
Strategies for salvage therapy post CAR-T therapy failure in refractory/relapsed multiple myeloma patients	171
RRx-001 Exerts Neuroprotection Against LPS-Induced Microglia Activation and Neuroinflammation Through Disturbing the TLR4 Pathway	170
Overview of Cannabis including Kampo Medicine and Therapy for Treatment of Dementia: A Review	158
In vitro effect of hydroxychloroquine on pluripotent stem cells and their cardiomyocytes derivatives	156
Harnessing the power of natural alkaloids: the emergent role in epilepsy therapy	152
Several major herb pairs containing Coptidis rhizoma: a review of key traditional uses, constituents and compatibility effects	150
Typing characteristics of metabolism-related genes in osteoporosis	149
Plant Source Derived Compound Exhibited In Silico Inhibition of Membrane Glycoprotein In SARS-CoV-2: Paving the Way to Discover a New Class of Compound For Treatment of COVID-19	141
Cost-effectiveness analysis of lenvatinib plus pembrolizumab compared with chemotherapy for patients with previously treated mismatch repair proficient advanced endometrial cancer in China	141
Case report: Dezocine’s rapid and sustained antidepressant effects	138
Improvement of solubility, dissolution, and bioavailability of phenytoin intercalated in Mg-Al layered double hydroxide	138
Ninjin’yoeito ameliorated PPE-induced pulmonary emphysema and anxiety/depressive-like behavior in aged C57BL/6J mice	137
Reynoutria japonica Houtt for Acute Respiratory Tract Infections in Adults and Children: A Systematic Review	136
Ameliorative Effects of Osthole on Experimental Renal Fibrosis in vivo and in vitro by Inhibiting IL-11/ERK1/2 Signaling	135
Contribution of patient registries to regulatory decision making on rare diseases medicinal products in Europe	134
Exploration of the Mechanism of Salvianolic Acid for Injection Against Ischemic Stroke: A Research Based on Computational Prediction and Experimental Validation	131

Transcriptome analysis revealed the role of mTOR and MAPK signaling pathways in the white strain of Hypsizygus marmoreus extracts-induced cell death of human hepatoma Hep3B cells	131
T-type calcium channel modulation by hydrogen sulfide in neuropathic pain conditions	128
Comprehensive Analysis of Chemical Structures That Have Been Tested as CFTR Activating Substances in a Publicly Available Database CandActCFTR	127
Potential Treat-to-Target Approach for Methamphetamine Use Disorder: A Pilot Study of Adenosine 2A Receptor Antagonist With Positron Emission Tomography	125
Phenotype-Based HPLC-Q-TOF-MS/MS Coupled With Zebrafish Behavior Trajectory Analysis System for the Identification of the Antidepressant Components in Methanol Extract of Anshen Buxin Six Pills	121
Editorial: Autoimmune and Inflammatory Rheumatic Diseases: Identifying Biomarkers of Response to Therapy With Biologics	121
Cost-utility analysis of using paliperidone palmitate in schizophrenia in China	120
Comparative study of the effects of the three kinds of Kampo-hozai: Ninjinyoeito, Hochuekkito, and Juzentaihoto on anxious and low sociability behavior using NPY-knockout zebrafish	120
Identification of potential quality markers of Zishen Yutai pill based on spectrum–effect relationship analysis	114
Traditional Chinese Medicine formula Dai-Zong-Fang alleviating hepatic steatosis in db/db mice via gut microbiota modulation	113
Efficacy and safety of Abelmoschus moschatus capsules combined with tripterygium glycoside tablets on diabetic nephropathy: A systematic review and meta-analysis	112
Editorial: Leukocyte biology and muscle pathology: Leukocytes as potential targets to control muscle inflammation, mass, and pain	110
Non-aromatizable androgens modulate the lipopolysaccharide induced expression of the P2X7 receptor in human adipocytes	109
Consideration in Randomized Placebo-Controlled Trial on Neck Pain to Avoid the Placebo Effect in Analgesic Action	109
The therapeutic potential of natural metabolites in targeting endocrine-independent HER-2-negative breast cancer	108
AI-assisted literature exploration of innovative Chinese medicine formulas	106
Network pharmacology‒based analysis of marine cyanobacteria derived bioactive compounds for application to Alzheimer’s disease	105
Editorial: Therapeutic drug monitoring (TDM): a useful tool for pediatric pharmacology applied to routine clinical practice, Volume II	103
Editorial: Oral mucosa and disorders: from drug discovery to development and translation	99
MicroRNAs Regulating Mitochondrial Function in Cardiac Diseases	98
Development of Synergy-Based Combination for Learning and Memory Using in vitro, in vivo and TLC-MS-Bioautographic Studies	98
Network pharmacology and experimental verification-based strategy to explore the underlying mechanism of Liu Jun An Wei formula in the treatment of gastrointestinal reactions caused by chemotherapy fo	98
Impact of domiciliary administration of NSAIDs on COVID-19 hospital outcomes: an unCoVer analysis	98
Sex, Pramipexole and Tiagabine Affect Behavioral and Hormonal Response to Traumatic Stress in a Mouse Model of PTSD	97
Effects of public reporting of prescription indicators on patient choices: evidence from propensity scores matching	97
Editorial: Interplays and Functions of Gaseous Mediators: From Underlying Mechanisms to Therapeutic Approaches in Cardiovascular Diseases	96
Comparison of pharmacokinetics and safety between CE-fosphenytoin sodium, fosphenytoin sodium, and phenytoin sodium after intravenous and intramuscular administration in healthy volunteers	96
Apple pectin-based Zataria multiflora essential oil (ZEO) nanoemulsion: An approach to enhance ZEO DNA damage induction in breast cancer cells as in vitro and in silico studies reveal	95
Title: P2x7 Receptor Activation and Estrogen Status Drive Neuroinflammatory Mechanisms in a Rat Model for Dry Eye	94
Paeonol attenuates retinopathy in streptozotocin-induced diabetes in rats by regulating the oxidative stress and polyol pathway	92
Antisense Oligonucleotide-Based Therapy on miR-181a-5p Alleviates Cartilage Degradation of Temporomandibular Joint Osteoarthritis via Promoting SIRT1	92
Liu Shen Capsule Alters Airway Microbiota Composition and Metabolite Profiles in Healthy Humans	91
Indirect effect of alpha-1-antitrypsin on endotoxin-induced IL-1β secretion from human PBMCs	91
Sputum microbe community alterations induced by long-term inhaled corticosteroid use are associated with airway function in chronic obstructive pulmonary disease patients based on metagenomic next-gen	91
Cytoprotective Effects of Water Soluble Dihydropyrimidinthione Derivative Against UV-B Induced Human Corneal Epithelial Cell Photodamage	91
Editorial: Streaming inflammation: From damage to healing and resilience–Volume II	91
A Multicenter Study of 239 Patients Aged Over 70 Years With Diffuse Large B-Cell Lymphoma in China	91
Cytotoxicity and reversal effect of sertraline, fluoxetine, and citalopram on MRP1- and MRP7-mediated MDR	90
In vivo pharmacokinetics of Glycyrrhiza uralensis polysaccharides	88
Editorial: Evolution of phytochemicals and phytotherapies in the treatment and management of cancer: targeted strategies in cancer precision medicine	87
Does preterm birth increase the initiation of antidepressant use during the postpartum? A population-based investigation	86
Hepatoprotective Efficacy and Interventional Mechanism of Qijia Rougan Decoction in Liver Fibrosis	86
Extracellular vesicles mediate biological information delivery: A double-edged sword in cardiac remodeling after myocardial infarction	86
FMS-Related Tyrosine Kinase 3 Ligand Promotes Radioresistance in Esophageal Squamous Cell Carcinoma	85
Ginseng and Polygonum multiflorum formula protects brain function in Alzheimer’s disease	84
Unknown adverse drug reactions from spontaneous reports in a hospital setting: characterization, follow-up, and contribution to the pharmacovigilance system	84
Interleukin 22 and its association with neurodegenerative disease activity	84
Experience of a Strategy Including CYP2C19 Preemptive Genotyping Followed by Therapeutic Drug Monitoring of Voriconazole in Patients Undergoing Allogenic Hematopoietic Stem Cell Transplantation	84
Human matters in asthma: Considering the microbiome in pulmonary health	84
Editorial: Advances on targeted nanomedicines for atherosclerosis	82

Association between hyperuricemia and all-cause mortality in people taken Statins: a retrospective cohort study	82
Editorial: Dissecting Traditional Medicine via Chemical and Biochemical Techniques: Advanced Analytics and Novel Paradigms	81
Astragaloside IV Alleviates Intestinal Barrier Dysfunction via the AKT-GSK3β-β-Catenin Pathway in Peritoneal Dialysis	81
Canagliflozin Prevents Lipid Accumulation, Mitochondrial Dysfunction, and Gut Microbiota Dysbiosis in Mice With Diabetic Cardiovascular Disease	81
Editorial: Impact of anesthetics on cancer behavior and outcome	81
Pharmacokinetics and absorption mechanism of tandospirone citrate	80
Dioscin Reduces Vascular Damage in the Retina of db/db Mice by Inhibiting the VEGFA Signaling Pathway	79
Clinical study of ganshuang granule combined with tenofovir in the treatment of chronic hepatitis B complicated with nonalcoholic fatty liver disease	79
Editorial: Pharmacogenetics and pharmacogenomics in Latin America: ethnic variability, new insights in advances and perspectives: a RELIVAF-CYTED initiative, Volume II	79
Cost-effectiveness of empagliflozin for the treatment of heart failure: a systematic review	78
Escitalopram oxalate-loaded chitosan nanoparticle in situ gel formulation intended for direct nose-to-brain delivery: in vitro, ex vivo, and in vivo pharmacokinetic evaluation	78
Chinese herbal compound for multidrug-resistant or extensively drug-resistant bacterial pneumonia: a meta-analysis and trial sequential analysis with association rule mining to identify core herb comb	78
Olmesartan Attenuates Single-Lung Ventilation Induced Lung Injury via Regulating Pulmonary Microbiota	77
Tuo-Min-Ding-Chuan Decoction Alleviate Ovalbumin-Induced Allergic Asthma by Inhibiting Mast Cell Degranulation and Down-Regulating the Differential Expression Proteins	76
Research Trends and Collaboration Patterns on Polymyxin Resistance: A Bibliometric Analysis (2010–2019)	76
Identification of highly effective inhibitors against SARS-CoV-2 main protease: From virtual screening to in vitro study	76
The Function of Natural Polysaccharides in the Treatment of Ulcerative Colitis	75
Pterostilbene Alleviates Cholestasis by Promoting SIRT1 Activity in Hepatocytes and Macrophages	74
The role of NLRP3 inflammasome in hepatocellular carcinoma	74
Plasma calcitonin gene-related peptide and nitric oxide predict therapeutic response to amlodipine in pediatric primary hypertension	73
Benefits and Safety of Chinese Herbal Medicine in Treating Psoriasis: An Overview of Systematic Reviews	73
Editorial: Methods in predictive toxicology 2023	73
The Chinese Herbal Prescription JieZe-1 Inhibits Membrane Fusion and the Toll-like Receptor Signaling Pathway in a Genital Herpes Mouse Model	73
Qishen Granule (QSG) Inhibits Monocytes Released From the Spleen and Protect Myocardial Function via the TLR4-MyD88-NF-κB p65 Pathway in Heart Failure Mice	73
New use of an old drug: mechanism of oseltamivir phosphate inhibiting liver cancer through regulation of lipophagy via NEU1	72
Post-marketing safety surveillance of dalfampridine for multiple sclerosis using FDA adverse event reporting system	72
Corrigendum: Shu-Xie decoction alleviates oxidative stress and colon injury in acute sleep-deprived mice by suppressing p62/KEAP1/NRF2/HO1/NQO1 signaling	72
Could peripheral 5-HT level be used as a biomarker for depression diagnosis and treatment? A narrative minireview	71
Editorial: Utilizing omics strategies to discover new drug targets for cancers	70
Corrigendum: Xenon attenuated neonatal lipopolysaccharide exposure induced neuronal necroptosis and subsequently improved cognition in juvenile rats	70
Retraction: CXCL6 promotes renal interstitial fibrosis in diabetic nephropathy by activating JAK/STAT3 signaling pathway	69
An Ethnobotanical Study of Medicinal Plants in Kinmen	69
Corrigendum: Sanguisorba officinalis L. Suppresses Triple-Negative Breast Cancer Metastasis by Inhibiting Late-Phase Autophagy via Hif-1α/Caveolin-1 Signaling	69
Mechanism Underlying Acupuncture Therapy in Spinal Cord Injury: A Narrative Overview of Preclinical Studies	69
Inhibitory effects of calcium channel blockers nisoldipine and nimodipine on ivacaftor metabolism and their underlying mechanism	69
Circular RNAs in ferroptosis: regulation mechanism and potential clinical application in disease	68
Erratum: Exploring the pharmacological action mechanism of Ligusticum Chuanxiong-Piper Longum couplet medicines on the treatment of migraine based on network pharmacology	68
Effect of Combined Perftoran and Indocyanine Green-Photodynamic Therapy on HypoxamiRs and OncomiRs in Lung Cancer Cells	68
Erratum: Isoflurane-lipid emulsion injection as an anticonvulsant and neuroprotectant treatment for nerve agent exposure	68
Caffeine in liver diseases: Pharmacology and toxicology	67
Pharmacogenomic-guided dosing of fluoropyrimidines beyond DPYD: time for a polygenic algorithm?	67
Diallyl Trisulfide Enhances the Survival of Multiterritory Perforator Skin Flaps	66
The macrocyclic lactone oxacyclododecindione reduces fibrosis progression	66
Pre-clinical toxicity assessment of Artemisia absinthium extract-loaded polymeric nanoparticles associated with their oral administration	66
Berberine Facilitates Extinction and Prevents the Return of Fear	66
A Novel Compound, Tanshinol Borneol Ester, Ameliorates Pressure Overload-Induced Cardiac Hypertrophy by Inhibiting Oxidative Stress via the mTOR/β-TrCP/NRF2 Pathway	66
Discovery of novel benzylquinazoline molecules as p97/VCP inhibitors	65
Effects of long-term antipsychotic medication on brain instability in first-episode schizophrenia patients: a resting-state fMRI study	65
Chemical synthesis of a reported p47phox/p22phox inhibitor and characterization of its instability and irreproducible activity	65
Multi-omic analysis reveals that Bacillus licheniformis enhances pekin ducks growth performance via lipid metabolism regulation	65
Antirheumatoid Arthritic Effects of Sabia parviflora Wall. Leaf Extracts via the NF-κB Pathway and Transient Receptor Potential Protein Family	65
Functional effects of drugs and toxins interacting with NaV1.4	65
Corrigendum: The Role of High-Content Complex Dietary Fiber in Medical Nutrition Therapy for Gestational Diabetes Mellitus	64
Accentuating CircRNA-miRNA-Transcription Factors Axis: A Conundrum in Cancer Research	64
Menisoxoisoaporphine A, a novel oxoisoaporphine alkaloid from Menispermi Rhizoma, inhibits inflammation by targeting PDE4B	64
IgG-like Bispecific Antibody CD3×EpCAM Generated by Split Intein Against Colorectal Cancer	64
Corrigendum: The Extract of Sonneratia apetala Leaves and Branches Ameliorates Hyperuricemia in Mice by Regulating Renal Uric Acid Transporters and Suppressing the Activation of the JAK/STAT Signaling	64
Neuroregeneration of injured peripheral nerve by fraction B of catfish epidermal secretions through the reversal of the apoptotic pathway and DNA damage	64
Corrigendum: Editorial: The mechanisms of action of anti-SARS-CoV-2 drugs	63
Potential Natural Small Molecular Compounds for the Treatment of Chronic Obstructive Pulmonary Disease: An Overview	62
Corrigendum: Comparison of the effectiveness and safety of perampanel and oxcarbazepine as monotherapy in children and adolescents with newly diagnosed focal epilepsy	62
Current situation and future development of the biopharmaceutical industry in China: A mixed-method study	62
Investigating the therapeutic potential of hesperidin targeting CRISP2 in intervertebral disc degeneration and cancer risk mitigation	61
Proteomics Study Reveals the Anti-Depressive Mechanisms and the Compatibility Advantage of Chaihu-Shugan-San in a Rat Model of Chronic Unpredictable Mild Stress	61
Role of ferroptosis in atrial fibrillation: a review	61
Pharmacist-Urologist Collaborative Management Improves Clinical Outcomes in Patients With Castration-Resistant Prostate Cancer Receiving Enzalutamide	60
Gaboxadol in Fragile X Syndrome: A 12-Week Randomized, Double-Blind, Parallel-Group, Phase 2a Study	60
Ferroptosis, pathogenesis and therapy in AS co-depression disease	60
Economic impact of individualized antimicrobial dose optimization in the critically ill patient in Spain	60
Significance of LRFN4 in prognosis and tumor microenvironment of lung adenocarcinoma	60
Research Progress of RNA Methylation Modification in Colorectal Cancer	59
The Efficacy and Safety of Chinese Herbal Medicine Xianling Gubao Capsule Combined With Alendronate in the Treatment of Primary Osteoporosis: A Systematic Review and Meta-Analysis of 20 Randomized Con	59
The clinically applied PARP inhibitor talazoparib ameliorates imiquimod-induced psoriasis in mice without reducing skin inflammation	59
Network pharmacology and transcriptomics reveal the mechanisms of FFBZL in the treatment of oral squamous cell carcinoma	59
Development of a vaccine against the synthetic opioid U-47700	59
MicroRNA 449a can Attenuate Protective Effect of Urokinase Against Pulmonary Embolism	58
Resveratrol Attenuates High Glucose-Induced Osteoblast Dysfunction via AKT/GSK3β/FYN-Mediated NRF2 Activation	58
Editorial: Chronic pain: what is the mechanism?	58
Potential efficacy and mechanisms of icariin for the animal model of osteonecrosis of the femoral head	58
Transcriptome analysis revealed the genes and major pathways involved in prunetrin treated hepatocellular carcinoma cells	57

Gut microbiome-mediated mechanisms in aging-related diseases: are probiotics ready for prime time?	57
Healthcare professional perspectives on medication challenges in the post-stroke patient	57
Long-term administration of bumetanide improve functional recovery after spinal cord injury in rats	56
Integrated network pharmacology and experimental analysis unveil multi-targeted effect of 18α- glycyrrhetinic acid against non-small cell lung cancer	56
Dynamic risk stratification and treatment optimization in sepsis: the role of NLPR	56
SARS-CoV-2 infection dysregulates the expression of clinically relevant drug metabolizing enzymes in Vero E6 cells and membrane transporters in human lung tissues	56
Male mice treated with combined anti-fibrotic therapeutics, IPW5371 and tadalafil, are predisposed to adverse cardiovascular events	56
A PDE10A inhibitor CPL500036 is a novel agent modulating striatal function devoid of most neuroleptic side-effects	55
Pichia pastoris secreted peptides crossing the blood-brain barrier and DSIP fusion peptide efficacy in PCPA-induced insomnia mouse models	55
Treatment of Poor Sperm Quality and Erectile Dysfunction With Oral Pentoxifylline: A Systematic Review	54
Z1456467176 alleviates gouty arthritis by allosterically modulating P2X7R to inhibit NLRP3 inflammasome activation	54
Bibliometric and visualized analysis of sodium–Glucose cotransporter 2 inhibitors	54
Efficacy, safety and mechanism of Honghua Xiaoyao Pill in the treatment of peri-menopausal syndrome: A study protocol for a randomized controlled trial	54
Comparison of remimazolam and propofol combined with low dose esketamine for pediatric same-day painless bidirectional endoscopy: a randomized, controlled clinical trial	54
An Update on the Effects of Probiotics on Gastrointestinal Cancers	54
Case Report: Rhabdomyolysis secondary to vildagliptin overdose in a suicidal attempt: A case report and brief literature review	54
Appropriateness of Antibiotic Prescriptions in Chinese Primary Health Care and the Impact of the COVID-19 Pandemic: A Typically Descriptive and Longitudinal Database Study in Yinchuan City	54
A novel phenolic derivative inhibits AHL-dependent quorum sensing signaling in Pseudomonas aeruginosa	53
Efficacy and safety of sequential immunosuppressive treatment for severe IgA nephropathy: A retrospective study	53
Metabolic Profiling Analysis of the Effect and Mechanism of Gushiling Capsule in Rabbits With Glucocorticoid-Induced Osteonecrosis of the Femoral Head	53
Isatin improves oligoasthenospermia caused by busulfan by regulating GSH/GPX4 axis to inhibit ferroptosis	53
Predicting individual-specific cardiotoxicity responses induced by tyrosine kinase inhibitors	53
Hemoglobin α-derived peptides VD-hemopressin (α) and RVD-hemopressin (α) are involved in electroacupuncture inhibition of chronic pain	53
Unraveling the pathogenic mechanism of a novel filamin a frameshift variant in periventricular nodular heterotopia	53
Wenshen-Jianpi prescription, a Chinese herbal medicine, improves visceral hypersensitivity in a rat model of IBS-D by regulating the MEK/ERK signal pathway	53
A Review on the Ethnopharmacology and Phytochemistry of the Neotropical Sages (Salvia Subgenus Calosphace; Lamiaceae) Emphasizing Mexican Species	53
Centella asiatica Alters Metabolic Pathways Associated With Alzheimer’s Disease in the 5xFAD Mouse Model of ß-Amyloid Accumulation	53
Therapeutic drug monitoring practices of anti-infectives: An Asia-wide cross-sectional survey	52
A nano-preparation approach to enable the delivery of daphnoretin to potentiate the therapeutical efficacy in hepatocellular cancer	52
Piper sarmentosum Roxb. Attenuates Vascular Endothelial Dysfunction in Nicotine-Induced Rats	52
Editorial: Genomic discoveries and pharmaceutical development in urologic tumors	52
East Asian Herbal Medicine to Reduce Primary Pain and Adverse Events in Cancer Patients : A Systematic Review and Meta-Analysis With Association Rule Mining to Identify Core Herb Combination	52
The Amazonian kambô frog Phyllomedusa bicolor (Amphibia: Phyllomedusidae): Current knowledge on biology, phylogeography, toxinology, ethnopharmacology and medical aspects	52
Hermansky-Pudlak Syndrome: Identification of Novel Variants in the Genes HPS3, HPS5, and DTNBP1 (HPS-7)	52
Drug-related problems among transfusion-dependent thalassemia patients: A real-world evidence study	52
Association of EGFR Tyrosine Kinase Inhibitor Treatment With Progression-Free Survival Among Taiwanese Patients With Advanced Lung Adenocarcinoma and EGFR Mutation	51
Chronic Administration of COVID-19 Drugs Fluvoxamine and Lopinavir Shortens Action Potential Duration by Inhibiting the Human Ether‐à‐go‐go–Related Gene and Cav1.2	51
A New Strategy for Multitarget Drug Discovery/Repositioning Through the Identification of Similar 3D Amino Acid Patterns Among Proteins Structures: The Case of Tafluprost and its Effects on Cardiac Io	51
Activation of EP4 alleviates AKI-to-CKD transition through inducing CPT2-mediated lipophagy in renal macrophages	51
Chloroquine and Hydroxychloroquine Use During Pregnancy and the Risk of Adverse Pregnancy Outcomes Using Real-World Evidence	51
Tailoring second-line or above therapy for patients with advanced or metastatic gastric cancer: A multicenter real-world study	51
Pterostilbene in Combination With Mitochondrial Cofactors Improve Mitochondrial Function in Cellular Models of Mitochondrial Diseases	51
Effects of the Full Coverage Policy of Essential Medicines on Inequality in Medication Adherence: A Longitudinal Study in Taizhou, China	51
Prospective population pharmacokinetic study of tacrolimus in adult recipients early after liver transplantation: A comparison of Michaelis-Menten and theory-based pharmacokinetic models	51
Associations of Fentanyl, Sufentanil, and Remifentanil With Length of Stay and Mortality Among Mechanically Ventilated Patients: A Registry-Based Cohort Study	51
Buyang Huanwu Decoction alleviates cerebral ischemic injury through modulating caveolin-1-mediated mitochondrial quality control	51
Exploiting the anti-fibrotic effects of statins on thoracic aortic aneurysm progression: results from a meta-analysis and experimental data	50
Traditional Chinese Medicine in Treating Primary Podocytosis: From Fundamental Science to Clinical Research	50
The Future of Gene Therapy for Transfusion-Dependent Beta-Thalassemia: The Power of the Lentiviral Vector for Genetically Modified Hematopoietic Stem Cells	50
Effect of Fu Zheng Jie Du Formula on outcomes in patients with severe pneumonia receiving prone ventilation: a retrospective cohort study	50
The synergistic activity of SBC3 in combination with Ebselen against Escherichia coli infection	50
Xuanfei Pingchuan Capsules Ameliorate Autophagy in Human Bronchial Epithelial Cells by Inhibiting p38 Phosphorylation	50
Development and therapeutic evaluation of 5D3(CC-MLN8237)3.2 antibody-theranostic conjugates for PSMA-positive prostate cancer therapy	50
A Betulinic Acid Derivative, BA5, Induces G0/G1 Cell Arrest, Apoptosis Like-Death, and Morphological Alterations in Leishmania sp	50
Kinin B1R Activation Induces Endoplasmic Reticulum Stress in Primary Hypothalamic Neurons	50
mPEG-PDLLA Micelles Potentiate Docetaxel for Intraperitoneal Chemotherapy in Ovarian Cancer Peritoneal Metastasis	50
Nephroprotective potential of Polyalthia longifolia roots against vancomycin-induced renal toxicity in experimental animals	50
Hydroxytyrosol Inhibits MDSCs and Promotes M1 Macrophages in Mice With Orthotopic Pancreatic Tumor	50
Bifidobacterium Strains Present Distinct Effects on the Control of Alveolar Bone Loss in a Periodontitis Experimental Model	50
Evaluation of variable new antigen receptors (vNARs) as a novel cathepsin S (CTSS) targeting strategy	50
Patient-Patient Similarity-Based Screening of a Clinical Data Warehouse to Support Ciliopathy Diagnosis	50
Effect of corticosteroids combined with cyclophosphamide or mycophenolate mofetil therapy for IgA nephropathy with stage 3 or 4 chronic kidney disease: A retrospective cohort study	50
Microbiome Analysis and Pharmacovigilance After Inhaled Glucocorticoid: Oral Dysbiosis With the Isolation of Three Rothia Species and Subsequent Sjögren’s Syndrome	50
Inhibition of PPARγ by BZ26, a GW9662 derivate, attenuated obesity-related breast cancer progression by inhibiting the reprogramming of mature adipocytes into to cancer associate adipocyte-like cells	49
Water-Soluble Tomato Extract Fruitflow Alters the Phosphoproteomic Profile of Collagen-Stimulated Platelets	49
Quantifying the integrated physiological effects of endothelin-1 on cardiovascular and renal function in healthy subjects: a mathematical modeling analysis	49
The Protective Effects of Lipid-Lowering Agents on Cardiovascular Disease and Mortality in Maintenance Dialysis Patients: Propensity Score Analysis of a Population-Based Cohort Study	49
Prediction of Immune-Related Adverse Events Induced by Immune Checkpoint Inhibitors With a Panel of Autoantibodies: Protocol of a Multicenter, Prospective, Observational Cohort Study	49
Integration of meta-analysis and network pharmacology analysis to investigate the pharmacological mechanisms of traditional Chinese medicine in the treatment of hepatocellular carcinoma	49
Butyrate Treatment of DSS-Induced Ulcerative Colitis Affects the Hepatic Drug Metabolism in Mice	49
Discovery of a novel natural compound, vitekwangin B, with ANO1 protein reduction properties and anticancer potential	49
Efficacy of Intra-Arterial Plus Intravesical Chemotherapy for High-Risk Non-Muscle-Invasive Bladder Cancer: A Pooled Analysis	49
Cymensifin A: a promising pharmaceutical candidate to defeat lung cancer via cellular reactive oxygen species-mediated apoptosis	49
Function-Wise Dual-Omics analysis for radiation pneumonitis prediction in lung cancer patients	49
Unlocking cellular traffic jams: olive oil-mediated rescue of CNG mutant channels	49
Factors influencing plasma concentration of voriconazole and voriconazole- N-oxide in younger adult and elderly patients	49
Editorial: Big data for biomedical research of inflammatory diseases	49
Wendan decoction in the treatment of nonalcoholic fatty liver disease: A systematic review and meta-analysis	49
The Role of Traditional Plant Knowledge in the Fight Against Infectious Diseases: A Meta-Analytic Study in the Catalan Linguistic Area	49
Time trends and regional variations in prices of anticancer medicines in China	49
Anticancer effects of OSW-1 on glioma cells via regulation of the PI3K/AKT signal pathway: A network pharmacology approach and experimental validation in vitro and in vivo	49
Phytochemicals targeting glycolysis in colorectal cancer therapy: effects and mechanisms of action	48
Cannabidiol Inhibits Multiple Ion Channels in Rabbit Ventricular Cardiomyocytes	48
Long-Term Cardiac Damage Associated With Abdominal Irradiation in Mice	48
Recent clinical evidence on nutrition, novel pharmacotherapy, and vaccination in inflammatory bowel diseases	48
Naoxintong capsule for treating cardiovascular and cerebrovascular diseases: from bench to bedside	48
Side-stepping the guardian of the genome: current cancer therapeutics targeting mutant p53	48
Three-Drug Regimens Containing Integrase Inhibitor Show Good Efficacy and Safety in Treatment-Naive Patients With HIV-1: A Bayesian Analysis	48
A minimal PBPK model to accelerate preclinical development of drugs against tuberculosis	48
Adaptive NK Cell Therapy Modulated by Anti-PD-1 Antibody in Gastric Cancer Model	47
First-in-human study to assess the safety, tolerability, pharmacokinetics and immunogenicity of DS002, an anti-nerve growth factor monoclonal antibody	47
Safety evaluation of medroxyprogesterone acetate: a pharmacovigilance analysis using FDA adverse event reporting system data	47
Pharmacogenetic and pharmacokinetic factors for dexmedetomidine-associated hemodynamic instability in pediatric patients	47
Model-informed precision dosing in vancomycin treatment	47
pH-induced conformational changes in the selectivity filter of a potassium channel lead to alterations in its selectivity and permeation properties	47