Frontiers in Pharmacology

Papers
(The TQCC of Frontiers in Pharmacology is 10. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-01-01 to 2026-01-01.)
ArticleCitations
Editorial: Therapeutic drug monitoring (TDM): a useful tool for pediatric pharmacology applied to routine clinical practice, Volume II768
Efficacy of interventions with live combined Bacillus subtilis and Enterococcus faecium enteric-coated capsules in metabolic associated fatty liver disease patients: a meta-analysis of randomized cont415
Quantum chemical calculations of nitrosamine activation and deactivation pathways for carcinogenicity risk assessment367
Association between hyperuricemia and all-cause mortality in people taken Statins: a retrospective cohort study361
pH-induced conformational changes in the selectivity filter of a potassium channel lead to alterations in its selectivity and permeation properties334
D-cycloserine effects on COPD and depression in a murine experimental model313
GraphTransNet: predicting epilepsy-related genes using a graph-augmented protein language model308
Traditional Chinese Medicine in Treating Primary Podocytosis: From Fundamental Science to Clinical Research272
Unraveling the pathogenic mechanism of a novel filamin a frameshift variant in periventricular nodular heterotopia236
Quantifying the integrated physiological effects of endothelin-1 on cardiovascular and renal function in healthy subjects: a mathematical modeling analysis235
Editorial: Chronic pain: what is the mechanism?226
Long-term clinical course and outcomes of patients with microscopic polyangiitis-associated interstitial lung disease202
Indirect effect of alpha-1-antitrypsin on endotoxin-induced IL-1β secretion from human PBMCs200
Corrigendum: Xenon attenuated neonatal lipopolysaccharide exposure induced neuronal necroptosis and subsequently improved cognition in juvenile rats196
Editorial: Oral mucosa and disorders: from drug discovery to development and translation194
Time trends and regional variations in prices of anticancer medicines in China188
Pre- and post-chemotherapy spermatogenesis in male patients with malignant bone and soft tissue tumors188
The categorizations of vasculogenic mimicry in clear cell renal cell carcinoma unveil inherent connections with clinical and immune features182
Editorial: Impact of anesthetics on cancer behavior and outcome161
Cyclohexene oxide CA, a derivative of zeylenone, exhibits anti-cancer activity in glioblastoma by inducing G0/G1 phase arrest through interference with EZH2159
Unlocking cellular traffic jams: olive oil-mediated rescue of CNG mutant channels152
Erratum: Isoflurane-lipid emulsion injection as an anticonvulsant and neuroprotectant treatment for nerve agent exposure151
Editorial: Interplays and Functions of Gaseous Mediators: From Underlying Mechanisms to Therapeutic Approaches in Cardiovascular Diseases150
Sputum microbe community alterations induced by long-term inhaled corticosteroid use are associated with airway function in chronic obstructive pulmonary disease patients based on metagenomic next-gen150
Impact of domiciliary administration of NSAIDs on COVID-19 hospital outcomes: an unCoVer analysis149
RRx-001 Exerts Neuroprotection Against LPS-Induced Microglia Activation and Neuroinflammation Through Disturbing the TLR4 Pathway149
AduCPI2 alleviates MSU-induced acute gouty arthritis in mice by inhibiting cathepsin S and the C5a-C5aR1 axis143
Editorial: Methods in predictive toxicology 2023138
Efficacy and safety of Abelmoschus moschatus capsules combined with tripterygium glycoside tablets on diabetic nephropathy: A systematic review and meta-analysis134
Integrating single-cell RNA-seq, bulk RNA-seq and network pharmacology reveals protective effect of salidroside in peritoneal dialysis-associated peritoneal fibrosis131
Corrigendum: Shu-Xie decoction alleviates oxidative stress and colon injury in acute sleep-deprived mice by suppressing p62/KEAP1/NRF2/HO1/NQO1 signaling131
Plasma calcitonin gene-related peptide and nitric oxide predict therapeutic response to amlodipine in pediatric primary hypertension130
Associations between ionomic profile and metabolic abnormalities in a murine model of sodium sulfide induced alopecia areata128
Safety evaluation of medroxyprogesterone acetate: a pharmacovigilance analysis using FDA adverse event reporting system data126
Nodosin Exerts an Anti-Colorectal Cancer Effect by Inhibiting Proliferation and Triggering Complex Cell Death in Vitro and in Vivo126
Differences in right ventricular function and response to targeted therapy between patients with IPAH and PAH-CHD125
Long-term administration of bumetanide improve functional recovery after spinal cord injury in rats125
Editorial: Utilizing omics strategies to discover new drug targets for cancers123
Role of ferroptosis in atrial fibrillation: a review123
Effect of Fu Zheng Jie Du Formula on outcomes in patients with severe pneumonia receiving prone ventilation: a retrospective cohort study122
The functional significance of vascular DNA hypermethylation in atherosclerosis: a historical perspective121
CDFA: Calibrated deep feature aggregation for screening synergistic drug combinations116
Potential efficacy and mechanisms of icariin for the animal model of osteonecrosis of the femoral head116
Does preterm birth increase the initiation of antidepressant use during the postpartum? A population-based investigation116
Chemical synthesis of a reported p47phox/p22phox inhibitor and characterization of its instability and irreproducible activity115
Case Report: Rhabdomyolysis secondary to vildagliptin overdose in a suicidal attempt: A case report and brief literature review114
Potential mechanisms of Lian-Zhi-Fan solution for TNBS-induced ulcerative colitis in rats via a metabolomics approach113
Interleukin 22 and its association with neurodegenerative disease activity109
Naoxintong capsule for treating cardiovascular and cerebrovascular diseases: from bench to bedside108
Development of a vaccine against the synthetic opioid U-47700102
Association between antihypertensive drugs and oral cancer: a drug target Mendelian randomization study102
Investigation of anti-depression effects and potential mechanisms of the ethyl acetate extract of Cynomorium songaricum Rupr. through the integration of in vivo experiments, LC-MS/MS chemical analysis100
Survival analysis of a 16-year cohort of follicular lymphoma patients receiving systemic treatment in Brazil100
Research hotspots and trend analysis of cell transplantation in traumatic spinal cord injury: a bibliometric and visualized analysis100
Wenshen-Jianpi prescription, a Chinese herbal medicine, improves visceral hypersensitivity in a rat model of IBS-D by regulating the MEK/ERK signal pathway99
Editorial: Women in nanomedicine98
Identification of highly effective inhibitors against SARS-CoV-2 main protease: From virtual screening to in vitro study97
Patient-Patient Similarity-Based Screening of a Clinical Data Warehouse to Support Ciliopathy Diagnosis97
Healthcare professional perspectives on medication challenges in the post-stroke patient96
The Protective Effects of Lipid-Lowering Agents on Cardiovascular Disease and Mortality in Maintenance Dialysis Patients: Propensity Score Analysis of a Population-Based Cohort Study93
Dioscin Reduces Vascular Damage in the Retina of db/db Mice by Inhibiting the VEGFA Signaling Pathway93
Corrigendum: Editorial: The mechanisms of action of anti-SARS-CoV-2 drugs92
Potential Treat-to-Target Approach for Methamphetamine Use Disorder: A Pilot Study of Adenosine 2A Receptor Antagonist With Positron Emission Tomography92
Comparison of pharmacokinetics and safety between CE-fosphenytoin sodium, fosphenytoin sodium, and phenytoin sodium after intravenous and intramuscular administration in healthy volunteers92
Traditional Chinese Medicine formula Dai-Zong-Fang alleviating hepatic steatosis in db/db mice via gut microbiota modulation91
Identification of potential quality markers of Zishen Yutai pill based on spectrum–effect relationship analysis91
Editorial: Leukocyte biology and muscle pathology: Leukocytes as potential targets to control muscle inflammation, mass, and pain91
Editorial: Evolution of phytochemicals and phytotherapies in the treatment and management of cancer: targeted strategies in cancer precision medicine90
Bibliometric and visualized analysis of sodium–Glucose cotransporter 2 inhibitors89
Comparative study of the effects of the three kinds of Kampo-hozai: Ninjinyoeito, Hochuekkito, and Juzentaihoto on anxious and low sociability behavior using NPY-knockout zebrafish88
Investigating the therapeutic potential of hesperidin targeting CRISP2 in intervertebral disc degeneration and cancer risk mitigation88
Drug-drug interactions between antithrombotics and direct-acting antivirals in hepatitis C virus (HCV) patients: A brief, updated report88
Inhibitory effects of calcium channel blockers nisoldipine and nimodipine on ivacaftor metabolism and their underlying mechanism88
Editorial: Genomic discoveries and pharmaceutical development in urologic tumors87
Non-aromatizable androgens modulate the lipopolysaccharide induced expression of the P2X7 receptor in human adipocytes87
Consideration in Randomized Placebo-Controlled Trial on Neck Pain to Avoid the Placebo Effect in Analgesic Action86
Preventive beneficial effects of cannabidiol in a reserpine-induced progressive model of parkinsonism85
Cost-utility analysis of using paliperidone palmitate in schizophrenia in China85
Retraction: CXCL6 promotes renal interstitial fibrosis in diabetic nephropathy by activating JAK/STAT3 signaling pathway84
Metabolic Profiling Analysis of the Effect and Mechanism of Gushiling Capsule in Rabbits With Glucocorticoid-Induced Osteonecrosis of the Femoral Head83
Significance of LRFN4 in prognosis and tumor microenvironment of lung adenocarcinoma83
Pterostilbene mitigates experimental pulmonary arterial hypertension by inhibiting endothelial-to-mesenchymal transition83
Editorial: Advances on targeted nanomedicines for atherosclerosis82
Erratum: Exploring the pharmacological action mechanism of Ligusticum Chuanxiong-Piper Longum couplet medicines on the treatment of migraine based on network pharmacology82
Pharmacist-Urologist Collaborative Management Improves Clinical Outcomes in Patients With Castration-Resistant Prostate Cancer Receiving Enzalutamide81
Influence of the ABCB1-rs1045642 gene polymorphism on blood drug concentration in voriconazole-treated patients with severe invasive fungal infection80
A retrospective analysis of factors associated with the length of hospital stay in COVID-19 patients treated with Nirmatrelvir / Ritonavir80
Profile of STING agonist and inhibitor research: a bibliometric analysis79
Case Report: Neurofilament light chain in the follow up of progressive multifocal leukoencephalopathy in a patient with multiple sclerosis treated with ocrelizumab79
Predicting individual-specific cardiotoxicity responses induced by tyrosine kinase inhibitors78
Transcriptome analysis revealed the genes and major pathways involved in prunetrin treated hepatocellular carcinoma cells78
Evaluation of variable new antigen receptors (vNARs) as a novel cathepsin S (CTSS) targeting strategy78
Diallyl Trisulfide Enhances the Survival of Multiterritory Perforator Skin Flaps77
Inhibition of retinal neovascularization by Dendrobium polysaccharides: a review77
Chrysophanol promotes M2 polarization and inhibits M1 polarization through the NF-κB signaling pathway to attenuate sepsis-associated acute kidney injury76
Long-Term Cardiac Damage Associated With Abdominal Irradiation in Mice76
Correction: The antipsychotics functional index (AFI) in schizophrenia76
Androgen receptor inhibitor ameliorates pulmonary arterial hypertension by enhancing the apoptosis level through suppressing the Notch3/Hes5 pathway76
Gastrointestinal injury in cardiopulmonary bypass: current insights and future directions75
Case report: Dezocine’s rapid and sustained antidepressant effects75
Cymensifin A: a promising pharmaceutical candidate to defeat lung cancer via cellular reactive oxygen species-mediated apoptosis75
The synergistic activity of SBC3 in combination with Ebselen against Escherichia coli infection75
A Multicenter Study of 239 Patients Aged Over 70 Years With Diffuse Large B-Cell Lymphoma in China74
Astragaloside IV Alleviates Intestinal Barrier Dysfunction via the AKT-GSK3β-β-Catenin Pathway in Peritoneal Dialysis74
Hemoglobin α-derived peptides VD-hemopressin (α) and RVD-hemopressin (α) are involved in electroacupuncture inhibition of chronic pain74
Dachengqi decoction for the treatment of acute pancreatitis: a comprehensive analysis based on metabolites, pharmacokinetics, and metabolites efficacy mechanisms73
Corrigendum: Comparison of the effectiveness and safety of perampanel and oxcarbazepine as monotherapy in children and adolescents with newly diagnosed focal epilepsy73
Menisoxoisoaporphine A, a novel oxoisoaporphine alkaloid from Menispermi Rhizoma, inhibits inflammation by targeting PDE4B72
Development and therapeutic evaluation of 5D3(CC-MLN8237)3.2 antibody-theranostic conjugates for PSMA-positive prostate cancer therapy72
A nano-preparation approach to enable the delivery of daphnoretin to potentiate the therapeutical efficacy in hepatocellular cancer72
New use of an old drug: mechanism of oseltamivir phosphate inhibiting liver cancer through regulation of lipophagy via NEU172
Natural products in treating diabetic kidney disease: a visualized bibliometric analysis71
Comparative long-term outcomes of first-line CDK4/6 inhibitors plus endocrine therapy versus endocrine therapy in patients with HR+/HER2-metastatic or advanced breast cancer: a meta-analysis71
Adverse events in different administration routes of amiodarone: a pharmacovigilance study based on the FDA adverse event reporting system71
Cardiovascular toxicities associated with chimeric antigen receptor T-cell therapy71
The clinical value of screening for acetaminophen in all patients with intentional overdose or altered mental status suspected to be secondary to overdose71
Effects of public reporting of prescription indicators on patient choices: evidence from propensity scores matching71
The clinically applied PARP inhibitor talazoparib ameliorates imiquimod-induced psoriasis in mice without reducing skin inflammation71
Innovative strategies for post-stroke depression: integrating traditional Chinese medicine with neurobiological insights, including the gut-brain axis71
Male mice treated with combined anti-fibrotic therapeutics, IPW5371 and tadalafil, are predisposed to adverse cardiovascular events71
Unveiling the hidden risk of caspofungin: insights from three adverse event reporting systems and network pharmacology integration71
Pharmacogenetic and pharmacokinetic factors for dexmedetomidine-associated hemodynamic instability in pediatric patients70
Multi-omic analysis reveals that Bacillus licheniformis enhances pekin ducks growth performance via lipid metabolism regulation70
Opportunities and challenges in the treatment of IgA nephropathy69
Research Progress of RNA Methylation Modification in Colorectal Cancer69
Impact of roxadustat on anemia management in infected patients undergoing long-term dialysis: a retrospective cohort analysis69
Beta-blocker exposure and survival outcomes in patients with advanced pancreatic ductal adenocarcinoma: a retrospective cohort study (BETAPANC)69
Circadian Pharmacological Effects of Paeoniflorin on Mice With Urticaria-like Lesions68
Integration of meta-analysis and network pharmacology analysis to investigate the pharmacological mechanisms of traditional Chinese medicine in the treatment of hepatocellular carcinoma68
Inhibitory effects of total triterpenoids isolated from the Hedyotis diffusa willd on H1975 cells68
Clinical study of ganshuang granule combined with tenofovir in the treatment of chronic hepatitis B complicated with nonalcoholic fatty liver disease68
Efficacy and safety of oral minoxidil in the treatment of alopecia: a single-arm rate meta-analysis and systematic review67
Integrated chemometric evaluation of morphological traits, chemical composition, and hepatotoxicity of Polygonum multiflorum67
Bibliometric analysis of research on retinoic acid in the field of kidney disorders67
Plant Source Derived Compound Exhibited In Silico Inhibition of Membrane Glycoprotein In SARS-CoV-2: Paving the Way to Discover a New Class of Compound For Treatment of COVID-1967
Discovery of a novel natural compound, vitekwangin B, with ANO1 protein reduction properties and anticancer potential67
Tripterygium wilfordii glycosides ameliorates collagen-induced arthritis and aberrant lipid metabolism in rats67
Comparative efficacy and acceptability of pharmacotherapies for postpartum depression: A systematic review and network meta-analysis67
A Betulinic Acid Derivative, BA5, Induces G0/G1 Cell Arrest, Apoptosis Like-Death, and Morphological Alterations in Leishmania sp67
Managing novel therapies and concomitant medications in chronic lymphocytic leukemia: key challenges66
Dihydroarteannuin Ameliorates Collagen-Induced Arthritis Via Inhibiting B Cell Activation by Activating the FcγRIIb/Lyn/SHP-1 Pathway66
Reynoutria japonica Houtt for Acute Respiratory Tract Infections in Adults and Children: A Systematic Review65
Title: Understanding a Low Vitamin D State in the Context of COVID-1965
Extracellular vesicles mediate biological information delivery: A double-edged sword in cardiac remodeling after myocardial infarction65
An overview of mechanisms, biomarkers, and treatment strategies for acquired anti-EGFR resistance in RAS wild-type colorectal cancer65
Effects of long-term antipsychotic medication on brain instability in first-episode schizophrenia patients: a resting-state fMRI study65
Exploiting the anti-fibrotic effects of statins on thoracic aortic aneurysm progression: results from a meta-analysis and experimental data64
Optimization of gabapentin dosage in pediatric patients with renal impairment: a physiologically based pharmacokinetic modeling approach64
Function-Wise Dual-Omics analysis for radiation pneumonitis prediction in lung cancer patients64
Enhancing therapeutic antibody profiling: orthogonal strategies for stability and quality assessment64
Dexmedetomidine inhibits abnormal muscle hypertrophy of myofascial trigger points via TNF-α/ NF-κB signaling pathway in rats64
Neuroregeneration of injured peripheral nerve by fraction B of catfish epidermal secretions through the reversal of the apoptotic pathway and DNA damage64
Dynamic risk stratification and treatment optimization in sepsis: the role of NLPR63
In vivo pharmacokinetics of Glycyrrhiza uralensis polysaccharides63
Computational and experimental pharmacology to decode the efficacy of Theobroma cacao L. against doxorubicin-induced organ toxicity in EAC-mediated solid tumor-induced mice63
Microbiome Analysis and Pharmacovigilance After Inhaled Glucocorticoid: Oral Dysbiosis With the Isolation of Three Rothia Species and Subsequent Sjögren’s Syndrome63
Editorial: Pharmacogenetics and pharmacogenomics in Latin America: ethnic variability, new insights in advances and perspectives: a RELIVAF-CYTED initiative, Volume II63
Challenges in Treating Genodermatoses: New Therapies at the Horizon63
Berberine Facilitates Extinction and Prevents the Return of Fear62
Integrated network pharmacology and experimental analysis unveil multi-targeted effect of 18α- glycyrrhetinic acid against non-small cell lung cancer62
Icotinib derivatives as tyrosine kinase inhibitors with anti-esophageal squamous carcinoma activity62
Emerging Nanotheranostics for 5-Fluorouracil in Cancer Therapy: A Systematic Review on Efficacy, Safety, and Diagnostic Capability62
Hermansky-Pudlak Syndrome: Identification of Novel Variants in the Genes HPS3, HPS5, and DTNBP1 (HPS-7)62
Assessment of Fasudil on Contrast-Associated Acute Kidney Injury Using Multiparametric Renal MRI62
Traditional Chinese medicine in the prevention of diabetes mellitus and cardiovascular complications: mechanisms and therapeutic approaches62
In vitro effect of hydroxychloroquine on pluripotent stem cells and their cardiomyocytes derivatives61
Which is the optimal choice in lipid-lowering therapy for reducing major cardiovascular events? a network meta-analysis61
Myristic acid beneficially modulates intervertebral disc degeneration by preventing endplate osteochondral remodeling and vertebral osteoporosis in naturally aged mice61
Network pharmacology-based and experimental identification of the effects of Renshen Yangrong decoction on myocardial infarction61
Efficacy and safety of sequential immunosuppressive treatment for severe IgA nephropathy: A retrospective study61
Tailoring second-line or above therapy for patients with advanced or metastatic gastric cancer: A multicenter real-world study60
Overview of Cannabis including Kampo Medicine and Therapy for Treatment of Dementia: A Review60
The Transcultural Adaptation and Validation of the Chinese Version of the Duke Anticoagulation Satisfaction Scale60
Corrigendum: Sanguisorba officinalis L. Suppresses Triple-Negative Breast Cancer Metastasis by Inhibiting Late-Phase Autophagy via Hif-1α/Caveolin-1 Signaling60
Cost-effectiveness of empagliflozin for the treatment of heart failure: a systematic review60
Editorial: Dissecting Traditional Medicine via Chemical and Biochemical Techniques: Advanced Analytics and Novel Paradigms60
Transcriptome analysis revealed the role of mTOR and MAPK signaling pathways in the white strain of Hypsizygus marmoreus extracts-induced cell death of human hepatoma Hep3B cells60
Factors influencing plasma concentration of voriconazole and voriconazole- N-oxide in younger adult and elderly patients59
Qishen Granule (QSG) Inhibits Monocytes Released From the Spleen and Protect Myocardial Function via the TLR4-MyD88-NF-κB p65 Pathway in Heart Failure Mice59
ALG-bFGF Hydrogel Inhibiting Autophagy Contributes to Protection of Blood–Spinal Cord Barrier Integrity via PI3K/Akt/FOXO1/KLF4 Pathway After SCI59
The macrocyclic lactone oxacyclododecindione reduces fibrosis progression59
Polygala tenuifolia and Acorus tatarinowii in the treatment of Alzheimer’s disease: a systematic review and meta-analysis58
Prediction of Immune-Related Adverse Events Induced by Immune Checkpoint Inhibitors With a Panel of Autoantibodies: Protocol of a Multicenter, Prospective, Observational Cohort Study58
Factors associated with medication adherence among children with rheumatic diseases58
Prospective population pharmacokinetic study of tacrolimus in adult recipients early after liver transplantation: A comparison of Michaelis-Menten and theory-based pharmacokinetic models58
Oxylipins as therapeutic indicators of herbal medicines in cardiovascular diseases: a review58
A minimal PBPK model to accelerate preclinical development of drugs against tuberculosis58
Ferroptosis, pathogenesis and therapy in AS co-depression disease58
The volatile oil of Acorus tatarinowii schott significantly attenuates neuroinflammatory damage in a rat model of tourette syndrome by inhibiting the p38 MAPK/NLRP3/STAT3 signaling pathway58
A PDE10A inhibitor CPL500036 is a novel agent modulating striatal function devoid of most neuroleptic side-effects58
Editorial: Streaming inflammation: From damage to healing and resilience–Volume II58
Inhibition of PPARγ by BZ26, a GW9662 derivate, attenuated obesity-related breast cancer progression by inhibiting the reprogramming of mature adipocytes into to cancer associate adipocyte-like cells58
Antirheumatoid Arthritic Effects of Sabia parviflora Wall. Leaf Extracts via the NF-κB Pathway and Transient Receptor Potential Protein Family58
Cost-effectiveness analysis of lenvatinib plus pembrolizumab compared with chemotherapy for patients with previously treated mismatch repair proficient advanced endometrial cancer in China58
Natural drugs targeting inflammation pathways can be used to treat atherosclerosis57
In situ sustained release of icariin from injectable thermosensitive PLGA-PEG-PLGA hydrogels combined with core decompression for steroid-induced osteonecrosis of femoral head57
Fuyuan decoction prevents nasopharyngeal carcinoma metastasis by inhibiting circulating tumor cells/ endothelial cells interplay and enhancing anti-cancer immune response57
Comparative efficacy of commercial Chinese polyherbal preparation for coronary microvascular dysfunction: a systematic review and network meta-analysis of randomized controlled trials57
Network pharmacology and experimental verification-based strategy to explore the underlying mechanism of Liu Jun An Wei formula in the treatment of gastrointestinal reactions caused by chemotherapy fo57
Post-marketing safety surveillance of dalfampridine for multiple sclerosis using FDA adverse event reporting system57
Therapeutic Drug Monitoring of Anti-Thymocyte Globulin in Allogeneic Stem Cell Transplantation: Proof of Concept57
Pharmacokinetics and absorption mechanism of tandospirone citrate57
Autophagy in renal fibrosis: Protection or promotion?57
Ethnobotanical study of medicinal plants used by the people of Mosop, Nandi County in Kenya56
Screening of anti-heart failure active compounds from fangjihuangqi decoction in verapamil-induced zebrafish model by anti-heart failure index approach56
Radiosensitization effect of iridium (III) complex on lung cancer cells via mitochondria apoptosis pathway56
Model-informed precision dosing in vancomycin treatment56
Commentary: Iridoids derived from Valeriana jatamansi jones alleviates neuroinflammation and blood spinal cord barrier permeability after spinal cord injury by activating the Nrf2/HO-1 signaling pathw56
Mechanism Underlying Acupuncture Therapy in Spinal Cord Injury: A Narrative Overview of Preclinical Studies56
Farrerol inhibits proliferation and migration of colorectal cancer via the VEGF signaling pathway: evidence from network pharmacology, molecular docking, molecular dynamics simulation, and in vitro ex55
The role of NLRP3 inflammasome in hepatocellular carcinoma55
Potential Natural Small Molecular Compounds for the Treatment of Chronic Obstructive Pulmonary Disease: An Overview55
Ophiopogonin D increase apoptosis by activating p53 via ribosomal protein L5 and L11 and inhibiting the expression of c-Myc via CNOT255
Role and regulators of N6-methyladenosine (m6A) RNA methylation in inflammatory subtypes of asthma: a comprehensive review55
Nephroprotective potential of Polyalthia longifolia roots against vancomycin-induced renal toxicity in experimental animals55
Unlocking the secrets of glucose metabolism reprogramming: the role in pulmonary diseases54
Apple pectin-based Zataria multiflora essential oil (ZEO) nanoemulsion: An approach to enhance ZEO DNA damage induction in breast cancer cells as in vitro and in silico studies reveal54
Autophagy plays an essential role in ultraviolet radiation-driven skin photoaging54
Brain-Derived Neurotrophic Factor-Mediated Neuroprotection in Glaucoma: A Review of Current State of the Art54
Network pharmacology and transcriptomics reveal the mechanisms of FFBZL in the treatment of oral squamous cell carcinoma54
Individualized, dynamic, and full-course vancomycin dosing prediction: a study on the customized dose model54
Endothelium glutamate receptors in brain pathology54
Honokiol Inhibits HIF-1α-Mediated Glycolysis to Halt Breast Cancer Growth54
Icariin and related metabolites in fibrosis management: pharmacological properties and molecular mechanism53
Acute myocardial infarction induced by avatrombopag: a case report53
Population pharmacokinetics and dosing optimization of unbound teicoplanin in Chinese adult patients53
Is it possible to diagnose therapeutic adherence in mild cognitive impairment and dementia patients in clinical practice?53
Research advances in drug therapy of endometriosis53
Functional characterization of the α1-adrenoceptor in adult male rat locus coeruleus neurons ex vivo53
Activation of EP4 alleviates AKI-to-CKD transition through inducing CPT2-mediated lipophagy in renal macrophages52
Resveratrol Attenuates High Glucose-Induced Osteoblast Dysfunction via AKT/GSK3β/FYN-Mediated NRF2 Activation52
Structural Insight Into Ryanodine Receptor Channelopathies52
Optimization of ivacaftor-loaded solid lipid nanoparticles for solubility enhancement52
LINC01559 drives osimertinib resistance in NSCLC through a ceRNA network regulating miR-320a/IGF2BP3 axis52
Sishen Pill and its active phytochemicals in treating inflammatory bowel disease and colon cancer: an overview52
A Novel Compound, Tanshinol Borneol Ester, Ameliorates Pressure Overload-Induced Cardiac Hypertrophy by Inhibiting Oxidative Stress via the mTOR/β-TrCP/NRF2 Pathway52
Indole-3-Carbinol (I3C) Protects the Heart From Ischemia/Reperfusion Injury by Inhibiting Oxidative Stress, Inflammation, and Cellular Apoptosis in Mice52
Genetic characterization of pediatric B-cell acute lymphoblastic leukemia in Argentina uncovers molecular heterogeneity and novel variants52
Strategy advancements in placental pharmacokinetics: from in vitro experiments to in silico prediction52
8 specific Chinese herbal injections combined with chemotherapy for breast cancer: a systematic review and network meta-analysis of comparative safety and efficacy52
Current situation and future development of the biopharmaceutical industry in China: A mixed-method study52
Artemisinin and its derivatives: all-rounders that may prevent the progression from lung injury to lung cancer51
MicroRNA 449a can Attenuate Protective Effect of Urokinase Against Pulmonary Embolism51
Ninjin’yoeito ameliorated PPE-induced pulmonary emphysema and anxiety/depressive-like behavior in aged C57BL/6J mice51
Prescription medication use of United States military service members by therapeutic classification51
Effect of berberine on cognitive function and β-amyloid precursor protein in Alzheimer’s disease models: a systematic review and meta-analysis51
Side-stepping the guardian of the genome: current cancer therapeutics targeting mutant p5351
Liu Shen Capsule Alters Airway Microbiota Composition and Metabolite Profiles in Healthy Humans51
Therapeutic drug monitoring of voriconazole and the impact of inflammation on plasma trough concentrations in children51
Machine learning methods for propensity and disease risk score estimation in high-dimensional data: a plasmode simulation and real-world data cohort analysis51
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