Frontiers in Pharmacology

Article	Citations
Toxic Mechanisms of Five Heavy Metals: Mercury, Lead, Chromium, Cadmium, and Arsenic	818
Turmeric and Its Major Compound Curcumin on Health: Bioactive Effects and Safety Profiles for Food, Pharmaceutical, Biotechnological and Medicinal Applications	330
The Bone Extracellular Matrix in Bone Formation and Regeneration	315
Advances in Oral Drug Delivery	280
Cell-Penetrating Peptides in Diagnosis and Treatment of Human Diseases: From Preclinical Research to Clinical Application	271
Biodegradable Polymeric Nanoparticles for Drug Delivery to Solid Tumors	249
Molecular Sets (MOSES): A Benchmarking Platform for Molecular Generation Models	243
The Drug-Resistance Mechanisms of Five Platinum-Based Antitumor Agents	242
Advances in Oral Drug Delivery for Regional Targeting in the Gastrointestinal Tract - Influence of Physiological, Pathophysiological and Pharmaceutical Factors	215
Dietary Polyphenols and Their Role in Oxidative Stress-Induced Human Diseases: Insights Into Protective Effects, Antioxidant Potentials and Mechanism(s) of Action	207
Nanocurcumin: A Promising Candidate for Therapeutic Applications	200
Modeling Parkinson’s Disease With the Alpha-Synuclein Protein	186
A Review of the Pharmacological Action of Astragalus Polysaccharide	179
Herbal Medicine for Cardiovascular Diseases: Efficacy, Mechanisms, and Safety	175
COVID-19: Is There Evidence for the Use of Herbal Medicines as Adjuvant Symptomatic Therapy?	166
Perceptions of healthcare professionals and patients on the role of the pharmacist in TB management in Pakistan: A qualitative study	163
PI3K/AKT Signal Pathway: A Target of Natural Products in the Prevention and Treatment of Alzheimer’s Disease and Parkinson’s Disease	162
DNA Repair Pathways in Cancer Therapy and Resistance	162
Ferroptosis and Its Potential Role in Human Diseases	159
Activation of PI3K/AKT/mTOR Pathway Causes Drug Resistance in Breast Cancer	156
Herb and Spices in Colorectal Cancer Prevention and Treatment: A Narrative Review	150
The Therapeutic Potential of Anthocyanins: Current Approaches Based on Their Molecular Mechanism of Action	146
Uric Acid and Cardiovascular Disease: An Update From Molecular Mechanism to Clinical Perspective	143
A Snapshot of the Global Race for Vaccines Targeting SARS-CoV-2 and the COVID-19 Pandemic	142
From Animal Poisons and Venoms to Medicines: Achievements, Challenges and Perspectives in Drug Discovery	141

Comparative effectiveness of individualized longer and standardized shorter regimens in the treatment of multidrug resistant tuberculosis in a high burden country	141
The Role of the CXCL12/CXCR4/CXCR7 Chemokine Axis in Cancer	139
SIRT1 Activation by Natural Phytochemicals: An Overview	139
Histone Deacetylases Inhibitors in Neurodegenerative Diseases, Neuroprotection and Neuronal Differentiation	139
PROTAC: An Effective Targeted Protein Degradation Strategy for Cancer Therapy	138
Discovering Anti-Cancer Drugs via Computational Methods	137
Pharmacological Properties of Chalcones: A Review of Preclinical Including Molecular Mechanisms and Clinical Evidence	137
Overview of OxLDL and Its Impact on Cardiovascular Health: Focus on Atherosclerosis	136
Comprehensive Analysis of Cuproptosis-Related Genes in Immune Infiltration and Prognosis in Melanoma	132
Phytosterols: From Preclinical Evidence to Potential Clinical Applications	130
Dopamine Receptor Subtypes, Physiology and Pharmacology: New Ligands and Concepts in Schizophrenia	130
Fluvoxamine: A Review of Its Mechanism of Action and Its Role in COVID-19	128
PD-1/PD-L1 Checkpoint Inhibitors in Tumor Immunotherapy	127
Response to the Novel Corona Virus (COVID-19) Pandemic Across Africa: Successes, Challenges, and Implications for the Future	127
Effect of Berberine on Atherosclerosis and Gut Microbiota Modulation and Their Correlation in High-Fat Diet-Fed ApoE−/− Mice	123
Unraveling Plant Natural Chemical Diversity for Drug Discovery Purposes	121
Medicinal Plants as Sources of Active Molecules Against COVID-19	121
Therapeutic Potential of Centella asiatica and Its Triterpenes: A Review	113
Non-Alcoholic Steatohepatitis: A Review of Its Mechanism, Models and Medical Treatments	111
Fat Therapeutics: The Clinical Capacity of Adipose-Derived Stem Cells and Exosomes for Human Disease and Tissue Regeneration	110
Knowledge Mapping of Drug-Induced Liver Injury: A Scientometric Investigation (2010–2019)	109
Indian Medicinal Plants and Formulations and Their Potential Against COVID-19–Preclinical and Clinical Research	107
The Pharmacological Action of Kaempferol in Central Nervous System Diseases: A Review	106
Oral Curcumin With Piperine as Adjuvant Therapy for the Treatment of COVID-19: A Randomized Clinical Trial	103
Progressive 3D Printing Technology and Its Application in Medical Materials	103
Cellular and Molecular Pathways of COVID-19 and Potential Points of Therapeutic Intervention	102
AKT Inhibitors: New Weapons in the Fight Against Breast Cancer?	102
Neurodegenerative Disease and the NLRP3 Inflammasome	101
Resveratrol Modulates the Gut Microbiota and Inflammation to Protect Against Diabetic Nephropathy in Mice	101
P2X7 in Cancer: From Molecular Mechanisms to Therapeutics	101
Clinically-Relevant ABC Transporter for Anti-Cancer Drug Resistance	101
A Systematic Review of Plants With Antibacterial Activities: A Taxonomic and Phylogenetic Perspective	100
Anti-SARS-CoV Natural Products With the Potential to Inhibit SARS-CoV-2 (COVID-19)	98
Mesenchymal Stem Cell–Derived Exosomes: A Promising Biological Tool in Nanomedicine	97
Combination of Ruxolitinib and Eculizumab for Treatment of Severe SARS-CoV-2-Related Acute Respiratory Distress Syndrome: A Controlled Study	97
Cellular Mechanisms of Liver Fibrosis	96
Challenges for Drug Repurposing in the COVID-19 Pandemic Era	94
Heavy Metal Contaminations in Herbal Medicines: Determination, Comprehensive Risk Assessments, and Solutions	94
Novel and Emerging Therapies for Inflammatory Bowel Disease	94
Recent Advances in NAMPT Inhibitors: A Novel Immunotherapic Strategy	93
Neutrophilia and NETopathy as Key Pathologic Drivers of Progressive Lung Impairment in Patients With COVID-19	93
Current Prevention of COVID-19: Natural Products and Herbal Medicine	92
Interplay of EMT and CSC in Cancer and the Potential Therapeutic Strategies	92
A Review on the Potential Use of Medicinal Plants From Asteraceae and Lamiaceae Plant Family in Cardiovascular Diseases	91
The Role of Oxidative Stress and Natural Antioxidants in Ovarian Aging	88
Pharmacogenetics Guidelines: Overview and Comparison of the DPWG, CPIC, CPNDS, and RNPGx Guidelines	88
Baicalin Prevents Myocardial Ischemia/Reperfusion Injury Through Inhibiting ACSL4 Mediated Ferroptosis	87
Passiflora edulis: An Insight Into Current Researches on Phytochemistry and Pharmacology	87
The Evasion Mechanisms of Cancer Immunity and Drug Intervention in the Tumor Microenvironment	87
G Protein-Coupled Receptors in Taste Physiology and Pharmacology	86

Drug Shortage: Causes, Impact, and Mitigation Strategies	86
The Drug Repurposing for COVID-19 Clinical Trials Provide Very Effective Therapeutic Combinations: Lessons Learned From Major Clinical Studies	86
Resveratrol and Neuroprotection: Impact and Its Therapeutic Potential in Alzheimer's Disease	86
Cinnamomum Species: Bridging Phytochemistry Knowledge, Pharmacological Properties and Toxicological Safety for Health Benefits	85
Immunosuppressive Drugs and COVID-19: A Review	85
Advanced Approaches to Breast Cancer Classification and Diagnosis	85
Repurposing Drugs, Ongoing Vaccine, and New Therapeutic Development Initiatives Against COVID-19	84
Pathways Connecting Late-Life Depression and Dementia	82
A Comprehensive Review on the Therapeutic Potential of Curcuma longa Linn. in Relation to its Major Active Constituent Curcumin	81
Immune Checkpoint Inhibitor-Related Cytokine Release Syndrome: Analysis of WHO Global Pharmacovigilance Database	81
Celastrol: A Review of Useful Strategies Overcoming its Limitation in Anticancer Application	81
Exploring Phytochemicals for Combating Antibiotic Resistance in Microbial Pathogens	79
Kuijieyuan Decoction Improved Intestinal Barrier Injury of Ulcerative Colitis by Affecting TLR4-Dependent PI3K/AKT/NF-κB Oxidative and Inflammatory Signaling and Gut Microbiota	79
Remimazolam: Non-Clinical and Clinical Profile of a New Sedative/Anesthetic Agent	79
Natural Compounds With Antimicrobial and Antiviral Effect and Nanocarriers Used for Their Transportation	79
SIRT1 and SIRT2 Activity Control in Neurodegenerative Diseases	79
Targeting the Integrated Stress Response in Cancer Therapy	79
From Cannabis sativa to Cannabidiol: Promising Therapeutic Candidate for the Treatment of Neurodegenerative Diseases	78
FDX1 can Impact the Prognosis and Mediate the Metabolism of Lung Adenocarcinoma	78
Peroxisome Proliferator-Activated Receptors: Experimental Targeting for the Treatment of Inflammatory Bowel Diseases	77
Efficacy, Chemical Constituents, and Pharmacological Actions of Radix Paeoniae Rubra and Radix Paeoniae Alba	77
Psychedelic Communitas: Intersubjective Experience During Psychedelic Group Sessions Predicts Enduring Changes in Psychological Wellbeing and Social Connectedness	76
Curcumin as a Potential Treatment for COVID-19	76
DPP4 and ACE2 in Diabetes and COVID-19: Therapeutic Targets for Cardiovascular Complications?	76
Combination of an Autophagy Inducer and an Autophagy Inhibitor: A Smarter Strategy Emerging in Cancer Therapy	75
Inhaled Phosphodiesterase 4 (PDE4) Inhibitors for Inflammatory Respiratory Diseases	75
The Role of Tumor Inflammatory Microenvironment in Lung Cancer	75
Clinical Insights Into Novel Immune Checkpoint Inhibitors	74
Targeting Neutrophils to Treat Acute Respiratory Distress Syndrome in Coronavirus Disease	74
Neuropharmacological Effects of Quercetin: A Literature-Based Review	74
Hyaluronic Acid-Mediated Drug Delivery System Targeting for Inflammatory Skin Diseases: A Mini Review	73
Matrine: A Promising Natural Product With Various Pharmacological Activities	73
Polyphenols as Antitumor Agents Targeting Key Players in Cancer-Driving Signaling Pathways	73
Chinese Patent Medicines in the Treatment of Coronavirus Disease 2019 (COVID-19) in China	72
Berberine Inhibits Nod-Like Receptor Family Pyrin Domain Containing 3 Inflammasome Activation and Pyroptosis in Nonalcoholic Steatohepatitis via the ROS/TXNIP Axis	72
Review of Ongoing Activities and Challenges to Improve the Care of Patients With Type 2 Diabetes Across Africa and the Implications for the Future	72
Like Cures Like: Pharmacological Activity of Anti-Inflammatory Lipopolysaccharides From Gut Microbiome	71
Clinical Review: Navitoclax as a Pro-Apoptotic and Anti-Fibrotic Agent	71
Modeling and Targeting Alzheimer’s Disease With Organoids	71
Formation, Signaling and Occurrence of Specialized Pro-Resolving Lipid Mediators—What is the Evidence so far?	70
The Mechanism of Ferroptosis and Applications in Tumor Treatment	70
The Potential Role of Heparin in Patients With COVID-19: Beyond the Anticoagulant Effect. A Review	69
The Noradrenergic System in Parkinson’s Disease	69
Herbal Medicine in the Treatment of Non-Alcoholic Fatty Liver Diseases-Efficacy, Action Mechanism, and Clinical Application	69
Progress in the Understanding of the Mechanism of Tamoxifen Resistance in Breast Cancer	69
Epilepsy-Related Voltage-Gated Sodium Channelopathies: A Review	69
Genistein: A Review on its Anti-Inflammatory Properties	68
Hypertension Is Associated With Intestinal Microbiota Dysbiosis and Inflammation in a Brazilian Population	67
Kaempferol Protects Against Cerebral Ischemia Reperfusion Injury Through Intervening Oxidative and Inflammatory Stress Induced Apoptosis	67
Eicosanoids in Cancer: New Roles in Immunoregulation	67
Potential Therapeutic Options for COVID-19: Current Status, Challenges, and Future Perspectives	67
Baicalin Inhibits Ferroptosis in Intracerebral Hemorrhage	67
The Biological Functions and Clinical Applications of Integrins in Cancers	67
Pharmacotherapy of Behavioral and Psychological Symptoms of Dementia: State of the Art and Future Progress	66
Functions and Diseases of the Retinal Pigment Epithelium	66
Fecal Microbiota Transplantation for the Treatment of Inflammatory Bowel Disease: An Update	65
Case Report: Central Retinal Artery Occlusion in a COVID-19 Patient	65
Safety and Efficacy of Bromodomain and Extra-Terminal Inhibitors for the Treatment of Hematological Malignancies and Solid Tumors: A Systematic Study of Clinical Trials	65
Terpenoids From Cannabis Do Not Mediate an Entourage Effect by Acting at Cannabinoid Receptors	64
Calming the Storm: Natural Immunosuppressants as Adjuvants to Target the Cytokine Storm in COVID-19	64
Eicosanoids in Cancer: Prostaglandin E2 Receptor 4 in Cancer Therapeutics and Immunotherapy	64
Pharmacokinetics and Metabolism of Naringin and Active Metabolite Naringenin in Rats, Dogs, Humans, and the Differences Between Species	64
Pyroptosis in the Initiation and Progression of Atherosclerosis	64
Traditional Chinese Medicine: Role in Reducing β-Amyloid, Apoptosis, Autophagy, Neuroinflammation, Oxidative Stress, and Mitochondrial Dysfunction of Alzheimer’s Disease	63
Pharmacological Effects of Salvianolic Acid B Against Oxidative Damage	63
Idiopathic Pulmonary Fibrosis: An Update on Pathogenesis	63
Repurposing Sigma-1 Receptor Ligands for COVID-19 Therapy?	63
Caspase-9: A Multimodal Therapeutic Target With Diverse Cellular Expression in Human Disease	63
An Update on Antiviral Therapy Against SARS-CoV-2: How Far Have We Come?	63
Neuroprotective Effect of Danhong Injection on Cerebral Ischemia-Reperfusion Injury in Rats by Activation of the PI3K-Akt Pathway	62
Analgesic Effect of Acetaminophen: A Review of Known and Novel Mechanisms of Action	62
Quercetin Attenuates Atherosclerosis via Modulating Oxidized LDL-Induced Endothelial Cellular Senescence	62
Integrated PPI- and WGCNA-Retrieval of Hub Gene Signatures Shared Between Barrett's Esophagus and Esophageal Adenocarcinoma	61
The Inhibitory Effect of 6-Gingerol on Ubiquitin-Specific Peptidase 14 Enhances Autophagy-Dependent Ferroptosis and Anti-Tumor in vivo and in vitro	61
Chlorogenic Acid Improves NAFLD by Regulating gut Microbiota and GLP-1	61
Software Tools for Model-Informed Precision Dosing: How Well Do They Satisfy the Needs?	61
Cannabidiol as a Therapeutic Target: Evidence of its Neuroprotective and Neuromodulatory Function in Parkinson’s Disease	61
Intranasal Delivery of Targeted Nanoparticles Loaded With miR-132 to Brain for the Treatment of Neurodegenerative Diseases	61
PD-1/PD-L1 Based Combinational Cancer Therapy: Icing on the Cake	61
Analysis of Models of Doxorubicin-Induced Cardiomyopathy in Rats and Mice. A Modern View From the Perspective of the Pathophysiologist and the Clinician	61

Oxidative Stress and Hyper-Inflammation as Major Drivers of Severe COVID-19 and Long COVID: Implications for the Benefit of High-Dose Intravenous Vitamin C	60
Therapeutic Alliance and Rapport Modulate Responses to Psilocybin Assisted Therapy for Depression	60
Traditional Herbal Medicines, Bioactive Metabolites, and Plant Products Against COVID-19: Update on Clinical Trials and Mechanism of Actions	60
Mechanisms of Chemotherapy-Induced Neurotoxicity	60
Recommendation of Antimicrobial Dosing Optimization During Continuous Renal Replacement Therapy	60
Fisetin Attenuates Doxorubicin-Induced Cardiomyopathy In Vivo and In Vitro by Inhibiting Ferroptosis Through SIRT1/Nrf2 Signaling Pathway Activation	59
COVID-19 Therapeutic Options Under Investigation	59
Metformin: A Novel Weapon Against Inflammation	59
Sinapic Acid Ameliorates the Progression of Streptozotocin (STZ)-Induced Diabetic Nephropathy in Rats via NRF2/HO-1 Mediated Pathways	58
Trends in Antidiabetic Drug Discovery: FDA Approved Drugs, New Drugs in Clinical Trials and Global Sales	58
The Steps to Therapeutic Drug Monitoring: A Structured Approach Illustrated With Imatinib	58
Best Practice in the chemical characterisation of extracts used in pharmacological and toxicological research—The ConPhyMP—Guidelines12	58
The Anticancer Properties of Tanshinones and the Pharmacological Effects of Their Active Ingredients	58
Insight Into the Prospects for RNAi Therapy of Cancer	58
Lactoferrin Against SARS-CoV-2: In Vitro and In Silico Evidences	58
Dysfunctional Vascular Endothelium as a Driver of Atherosclerosis: Emerging Insights Into Pathogenesis and Treatment	57
Mitochondria Targeted Viral Replication and Survival Strategies—Prospective on SARS-CoV-2	57
Tanshinone IIA: A Review of its Anticancer Effects	57
JAK/STAT Signaling: Molecular Targets, Therapeutic Opportunities, and Limitations of Targeted Inhibitions in Solid Malignancies	57
The Therapeutic Landscape of Rheumatoid Arthritis: Current State and Future Directions	57
Multi-Target Approaches in Metabolic Syndrome	56
Untargeted Metabolomic Analysis of the Effects and Mechanism of Nuciferine Treatment on Rats With Nonalcoholic Fatty Liver Disease	56
Application of Pharmacokinetic-Pharmacodynamic Modeling in Drug Delivery: Development and Challenges	56
Drug Repurposing Screen for Compounds Inhibiting the Cytopathic Effect of SARS-CoV-2	56
Myricetin Inhibits SARS-CoV-2 Viral Replication by Targeting Mpro and Ameliorates Pulmonary Inflammation	56
Preliminary Experience With Low Molecular Weight Heparin Strategy in COVID-19 Patients	56
Phytochemicals as a Complement to Cancer Chemotherapy: Pharmacological Modulation of the Autophagy-Apoptosis Pathway	55
The Cross-Talk Between the Dopaminergic and the Immune System Involved in Schizophrenia	55
Cordyceps spp.: A Review on Its Immune-Stimulatory and Other Biological Potentials	55
A Review of the Pharmacological Properties of Psoralen	55
α1-Adrenergic Receptors in Neurotransmission, Synaptic Plasticity, and Cognition	55
Postoperative Ileus and Postoperative Gastrointestinal Tract Dysfunction: Pathogenic Mechanisms and Novel Treatment Strategies Beyond Colorectal Enhanced Recovery After Surgery Protocols	55
Integrated Metagenomic and Metabolomic Analyses of the Effect of Astragalus Polysaccharides on Alleviating High-Fat Diet–Induced Metabolic Disorders	55
Necroptosis: A Novel Pathway in Neuroinflammation	54
The Potential of Antiviral Peptides as COVID-19 Therapeutics	54
Chemotherapeutics-Induced Intestinal Mucositis: Pathophysiology and Potential Treatment Strategies	54
Calcium Permeable Channels in Cancer Hallmarks	54
Efficacy and Safety of Probiotics in Irritable Bowel Syndrome: A Systematic Review and Meta-Analysis	54
Methylene Blue Inhibits the SARS-CoV-2 Spike–ACE2 Protein-Protein Interaction–a Mechanism that can Contribute to its Antiviral Activity Against COVID-19	54
NSAID–Gut Microbiota Interactions	54
Advancements in Hydrogel-Based Drug Sustained Release Systems for Bone Tissue Engineering	54
Accelerating Therapeutics for Opportunities in Medicine: A Paradigm Shift in Drug Discovery	53
MicroRNA as an Important Target for Anticancer Drug Development	53
The Role of Interleukin-8 in Lung Inflammation and Injury: Implications for the Management of COVID-19 and Hyperinflammatory Acute Respiratory Distress Syndrome	53
Improvement of Gold Nanorods in Photothermal Therapy: Recent Progress and Perspective	53
Potential of Neglected and Underutilized Yams (Dioscorea spp.) for Improving Nutritional Security and Health Benefits	53
Turning the Tide: Natural Products and Natural-Product-Inspired Chemicals as Potential Counters to SARS-CoV-2 Infection	53
Toxicomicrobiomics: The Human Microbiome vs. Pharmaceutical, Dietary, and Environmental Xenobiotics	53
Poly(ADP-Ribose)Polymerase (PARP) Inhibitors and Radiation Therapy	52
Efficacy and Safety of Sophora flavescens (Kushen) Based Traditional Chinese Medicine in the Treatment of Ulcerative Colitis: Clinical Evidence and Potential Mechanisms	52
Minor Cannabinoids: Biosynthesis, Molecular Pharmacology and Potential Therapeutic Uses	52
Bibliometric Analysis of the Inflammasome and Pyroptosis in Brain	52
Possible Benefits of Faecalibacterium prausnitzii for Obesity-Associated Gut Disorders	52
Withania somnifera (L.) Dunal: Opportunity for Clinical Repurposing in COVID-19 Management	52
Phytochemistry and Pharmacological Activities of Wolfiporia cocos (F.A. Wolf) Ryvarden & Gilb	52
Medicinal Plants in COVID-19: Potential and Limitations	52
Brucine: A Review of Phytochemistry, Pharmacology, and Toxicology	52
Current Status of Septic Cardiomyopathy: Basic Science and Clinical Progress	52
Recent Insights Into SREBP as a Direct Mediator of Kidney Fibrosis via Lipid-Independent Pathways	52
Transforming Growth Factor-Beta (TGF-β) Signaling in Cancer-A Betrayal Within	52
Interleukin-6: A Novel Target for Cardio-Cerebrovascular Diseases	52
GLP-1 Receptor Agonists in Diabetic Kidney Disease: From Clinical Outcomes to Mechanisms	51
An Increasing Trend in the Prevalence of Polypharmacy in Sweden: A Nationwide Register-Based Study	51
Deciphering the Pharmacological Mechanisms of Taohe-Chengqi Decoction Extract Against Renal Fibrosis Through Integrating Network Pharmacology and Experimental Validation In Vitro and In Vivo	51
Bibliometric Analysis of Global Research on Cancer Photodynamic Therapy: Focus on Nano-Related Research	51
Formulation and Development of Transferrin Targeted Solid Lipid Nanoparticles for Breast Cancer Therapy	51
Gastrin Attenuates Renal Ischemia/Reperfusion Injury by a PI3K/Akt/Bad-Mediated Anti-apoptosis Signaling	51
Understanding the role of the gut microbiome in gastrointestinal cancer: A review	50
Enteric Coronavirus Infection and Treatment Modeled With an Immunocompetent Human Intestine-On-A-Chip	50
Glucosinolates From Cruciferous Vegetables and Their Potential Role in Chronic Disease: Investigating the Preclinical and Clinical Evidence	50
Gastroprotective Effect of Sinapic Acid on Ethanol-Induced Gastric Ulcers in Rats: Involvement of Nrf2/HO-1 and NF-κB Signaling and Antiapoptotic Role	50
Potential Natural Products Against Respiratory Viruses: A Perspective to Develop Anti-COVID-19 Medicines	50
A Systematic Review of the Preventive and Therapeutic Effects of Naringin Against Human Malignancies	50
New Trends in Pharmacological Treatments for Osteoarthritis	50
Targeting Tumor Associated Macrophages to Overcome Conventional Treatment Resistance in Glioblastoma	50
Mitochondrial MPTP: A Novel Target of Ethnomedicine for Stroke Treatment by Apoptosis Inhibition	50
First-Line Immune-Checkpoint Inhibitors in Non-Small Cell Lung Cancer: Current Landscape and Future Progress	50
System Xc−/GSH/GPX4 axis: An important antioxidant system for the ferroptosis in drug-resistant solid tumor therapy	50
Formononetin Attenuates Airway Inflammation and Oxidative Stress in Murine Allergic Asthma	50
Effectiveness and Safety of Oral Anticoagulants in Older Patients With Atrial Fibrillation: A Systematic Review and Meta-Analysis	49
New Insights Into Gut-Bacteria-Derived Indole and Its Derivatives in Intestinal and Liver Diseases	49
Dynamic Interleukin-6 Level Changes as a Prognostic Indicator in Patients With COVID-19	49
A Systematic Review of the Pharmacology, Toxicology and Pharmacokinetics of Matrine	49
Natural Compounds as Medical Strategies in the Prevention and Treatment of Psychiatric Disorders Seen in Neurological Diseases	48
Calcific Aortic Valve Disease-Natural History and Future Therapeutic Strategies	48
Patient-Related Risk Factors for Chemotherapy-Induced Nausea and Vomiting: A Systematic Review	48
Bilirubin Nanoparticles Reduce Diet-Induced Hepatic Steatosis, Improve Fat Utilization, and Increase Plasma β-Hydroxybutyrate	48
The Role of Photoactivated and Non-Photoactivated Verteporfin on Tumor	48
SARS-CoV-2 Switches ‘on’ MAPK and NFκB Signaling via the Reduction of Nuclear DUSP1 and DUSP5 Expression	48
Favipiravir Versus Arbidol for Clinical Recovery Rate in Moderate and Severe Adult COVID-19 Patients: A Prospective, Multicenter, Open-Label, Randomized Controlled Clinical Trial	48
A Review of Treatment of Coronavirus Disease 2019 (COVID-19): Therapeutic Repurposing and Unmet Clinical Needs	48
Monoamine Oxidase Inhibitors: A Review of Their Anti-Inflammatory Therapeutic Potential and Mechanisms of Action	48
Ferulic Acid Ameliorates Lipopolysaccharide-Induced Barrier Dysfunction via MicroRNA-200c-3p-Mediated Activation of PI3K/AKT Pathway in Caco-2 Cells	48
Innate Immunity in Diabetic Wound Healing: Focus on the Mastermind Hidden in Chronic Inflammatory	48
Multi-Omics Analysis of Microglial Extracellular Vesicles From Human Alzheimer’s Disease Brain Tissue Reveals Disease-Associated Signatures	48