Frontiers in Pharmacology

Papers
(The H4-Index of Frontiers in Pharmacology is 80. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-05-01 to 2025-05-01.)
ArticleCitations
Pre- and post-chemotherapy spermatogenesis in male patients with malignant bone and soft tissue tumors529
Individualized, dynamic, and full-course vancomycin dosing prediction: a study on the customized dose model365
Metabolite-assisted models improve risk prediction of coronary heart disease in patients with diabetes321
Potential of resveratrol in the treatment of interstitial lung disease301
Editorial: Women in nanomedicine257
Title: Understanding a Low Vitamin D State in the Context of COVID-19243
The forensic aspects of suicide and neurotrophin factors: a research study229
Understanding Stakeholder Views Regarding the Design of an Intervention Trial to Reduce Anticholinergic Burden: A Qualitative Study208
Upregulation of Phosphodiesterase 2A Augments T Cell Activation by Changing cGMP/cAMP Cross-Talk197
Strategies for salvage therapy post CAR-T therapy failure in refractory/relapsed multiple myeloma patients171
RRx-001 Exerts Neuroprotection Against LPS-Induced Microglia Activation and Neuroinflammation Through Disturbing the TLR4 Pathway170
Overview of Cannabis including Kampo Medicine and Therapy for Treatment of Dementia: A Review158
In vitro effect of hydroxychloroquine on pluripotent stem cells and their cardiomyocytes derivatives156
Harnessing the power of natural alkaloids: the emergent role in epilepsy therapy152
Several major herb pairs containing Coptidis rhizoma: a review of key traditional uses, constituents and compatibility effects150
Typing characteristics of metabolism-related genes in osteoporosis149
Cost-effectiveness analysis of lenvatinib plus pembrolizumab compared with chemotherapy for patients with previously treated mismatch repair proficient advanced endometrial cancer in China141
Plant Source Derived Compound Exhibited In Silico Inhibition of Membrane Glycoprotein In SARS-CoV-2: Paving the Way to Discover a New Class of Compound For Treatment of COVID-19141
Case report: Dezocine’s rapid and sustained antidepressant effects138
Improvement of solubility, dissolution, and bioavailability of phenytoin intercalated in Mg-Al layered double hydroxide138
Ninjin’yoeito ameliorated PPE-induced pulmonary emphysema and anxiety/depressive-like behavior in aged C57BL/6J mice137
Reynoutria japonica Houtt for Acute Respiratory Tract Infections in Adults and Children: A Systematic Review136
Ameliorative Effects of Osthole on Experimental Renal Fibrosis in vivo and in vitro by Inhibiting IL-11/ERK1/2 Signaling135
Contribution of patient registries to regulatory decision making on rare diseases medicinal products in Europe134
Exploration of the Mechanism of Salvianolic Acid for Injection Against Ischemic Stroke: A Research Based on Computational Prediction and Experimental Validation131
Transcriptome analysis revealed the role of mTOR and MAPK signaling pathways in the white strain of Hypsizygus marmoreus extracts-induced cell death of human hepatoma Hep3B cells131
T-type calcium channel modulation by hydrogen sulfide in neuropathic pain conditions128
Comprehensive Analysis of Chemical Structures That Have Been Tested as CFTR Activating Substances in a Publicly Available Database CandActCFTR127
Potential Treat-to-Target Approach for Methamphetamine Use Disorder: A Pilot Study of Adenosine 2A Receptor Antagonist With Positron Emission Tomography125
Phenotype-Based HPLC-Q-TOF-MS/MS Coupled With Zebrafish Behavior Trajectory Analysis System for the Identification of the Antidepressant Components in Methanol Extract of Anshen Buxin Six Pills121
Editorial: Autoimmune and Inflammatory Rheumatic Diseases: Identifying Biomarkers of Response to Therapy With Biologics121
Cost-utility analysis of using paliperidone palmitate in schizophrenia in China120
Comparative study of the effects of the three kinds of Kampo-hozai: Ninjinyoeito, Hochuekkito, and Juzentaihoto on anxious and low sociability behavior using NPY-knockout zebrafish120
Identification of potential quality markers of Zishen Yutai pill based on spectrum–effect relationship analysis114
Traditional Chinese Medicine formula Dai-Zong-Fang alleviating hepatic steatosis in db/db mice via gut microbiota modulation113
Efficacy and safety of Abelmoschus moschatus capsules combined with tripterygium glycoside tablets on diabetic nephropathy: A systematic review and meta-analysis112
Editorial: Leukocyte biology and muscle pathology: Leukocytes as potential targets to control muscle inflammation, mass, and pain110
Consideration in Randomized Placebo-Controlled Trial on Neck Pain to Avoid the Placebo Effect in Analgesic Action109
Non-aromatizable androgens modulate the lipopolysaccharide induced expression of the P2X7 receptor in human adipocytes109
The therapeutic potential of natural metabolites in targeting endocrine-independent HER-2-negative breast cancer108
AI-assisted literature exploration of innovative Chinese medicine formulas106
Network pharmacology‒based analysis of marine cyanobacteria derived bioactive compounds for application to Alzheimer’s disease105
Editorial: Therapeutic drug monitoring (TDM): a useful tool for pediatric pharmacology applied to routine clinical practice, Volume II103
Editorial: Oral mucosa and disorders: from drug discovery to development and translation99
Development of Synergy-Based Combination for Learning and Memory Using in vitro, in vivo and TLC-MS-Bioautographic Studies98
Network pharmacology and experimental verification-based strategy to explore the underlying mechanism of Liu Jun An Wei formula in the treatment of gastrointestinal reactions caused by chemotherapy fo98
Impact of domiciliary administration of NSAIDs on COVID-19 hospital outcomes: an unCoVer analysis98
MicroRNAs Regulating Mitochondrial Function in Cardiac Diseases98
Effects of public reporting of prescription indicators on patient choices: evidence from propensity scores matching97
Sex, Pramipexole and Tiagabine Affect Behavioral and Hormonal Response to Traumatic Stress in a Mouse Model of PTSD97
Editorial: Interplays and Functions of Gaseous Mediators: From Underlying Mechanisms to Therapeutic Approaches in Cardiovascular Diseases96
Comparison of pharmacokinetics and safety between CE-fosphenytoin sodium, fosphenytoin sodium, and phenytoin sodium after intravenous and intramuscular administration in healthy volunteers96
Apple pectin-based Zataria multiflora essential oil (ZEO) nanoemulsion: An approach to enhance ZEO DNA damage induction in breast cancer cells as in vitro and in silico studies reveal95
Title: P2x7 Receptor Activation and Estrogen Status Drive Neuroinflammatory Mechanisms in a Rat Model for Dry Eye94
Paeonol attenuates retinopathy in streptozotocin-induced diabetes in rats by regulating the oxidative stress and polyol pathway92
Antisense Oligonucleotide-Based Therapy on miR-181a-5p Alleviates Cartilage Degradation of Temporomandibular Joint Osteoarthritis via Promoting SIRT192
Liu Shen Capsule Alters Airway Microbiota Composition and Metabolite Profiles in Healthy Humans91
Indirect effect of alpha-1-antitrypsin on endotoxin-induced IL-1β secretion from human PBMCs91
Sputum microbe community alterations induced by long-term inhaled corticosteroid use are associated with airway function in chronic obstructive pulmonary disease patients based on metagenomic next-gen91
Cytoprotective Effects of Water Soluble Dihydropyrimidinthione Derivative Against UV-B Induced Human Corneal Epithelial Cell Photodamage91
Editorial: Streaming inflammation: From damage to healing and resilience–Volume II91
A Multicenter Study of 239 Patients Aged Over 70 Years With Diffuse Large B-Cell Lymphoma in China91
Cytotoxicity and reversal effect of sertraline, fluoxetine, and citalopram on MRP1- and MRP7-mediated MDR90
In vivo pharmacokinetics of Glycyrrhiza uralensis polysaccharides88
Editorial: Evolution of phytochemicals and phytotherapies in the treatment and management of cancer: targeted strategies in cancer precision medicine87
Does preterm birth increase the initiation of antidepressant use during the postpartum? A population-based investigation86
Hepatoprotective Efficacy and Interventional Mechanism of Qijia Rougan Decoction in Liver Fibrosis86
Extracellular vesicles mediate biological information delivery: A double-edged sword in cardiac remodeling after myocardial infarction86
FMS-Related Tyrosine Kinase 3 Ligand Promotes Radioresistance in Esophageal Squamous Cell Carcinoma85
Interleukin 22 and its association with neurodegenerative disease activity84
Experience of a Strategy Including CYP2C19 Preemptive Genotyping Followed by Therapeutic Drug Monitoring of Voriconazole in Patients Undergoing Allogenic Hematopoietic Stem Cell Transplantation84
Human matters in asthma: Considering the microbiome in pulmonary health84
Ginseng and Polygonum multiflorum formula protects brain function in Alzheimer’s disease84
Unknown adverse drug reactions from spontaneous reports in a hospital setting: characterization, follow-up, and contribution to the pharmacovigilance system84
Association between hyperuricemia and all-cause mortality in people taken Statins: a retrospective cohort study82
Editorial: Advances on targeted nanomedicines for atherosclerosis82
Astragaloside IV Alleviates Intestinal Barrier Dysfunction via the AKT-GSK3β-β-Catenin Pathway in Peritoneal Dialysis81
Canagliflozin Prevents Lipid Accumulation, Mitochondrial Dysfunction, and Gut Microbiota Dysbiosis in Mice With Diabetic Cardiovascular Disease81
Editorial: Impact of anesthetics on cancer behavior and outcome81
Editorial: Dissecting Traditional Medicine via Chemical and Biochemical Techniques: Advanced Analytics and Novel Paradigms81
Pharmacokinetics and absorption mechanism of tandospirone citrate80
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