OOIR: Observatory of International Research

Papers

(The median citation count of Frontiers in Synaptic Neuroscience is 4. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-03-01 to 2024-03-01.)

Article	Citations
Dendritic Spine Plasticity: Function and Mechanisms	107
Dendritic Spines Shape Analysis—Classification or Clusterization? Perspective	79
Phosphorylation-Dependent Regulation of Ca2+-Permeable AMPA Receptors During Hippocampal Synaptic Plasticity	57
Semaphorins in Adult Nervous System Plasticity and Disease	49
Impact of Perineuronal Nets on Electrophysiology of Parvalbumin Interneurons, Principal Neurons, and Brain Oscillations: A Review	48
The Role of Rac GTPase in Dendritic Spine Morphogenesis and Memory	33
Bidirectional Dysregulation of AMPA Receptor-Mediated Synaptic Transmission and Plasticity in Brain Disorders	32
Neuroligins and Neurodevelopmental Disorders: X-Linked Genetics	30
Voltage-Gated Ca2+-Channel α1-Subunit de novo Missense Mutations: Gain or Loss of Function – Implications for Potential Therapies	30
The Creatine Transporter Unfolded: A Knotty Premise in the Cerebral Creatine Deficiency Syndrome	28
Psychedelics as a Treatment for Alzheimer’s Disease Dementia	26
The Good, the Bad and the Unknown Aspects of Ghrelin in Stress Coping and Stress-Related Psychiatric Disorders	25
The Synapse Diversity Dilemma: Molecular Heterogeneity Confounds Studies of Synapse Function	24
A Synaptic Framework for the Persistence of Memory Engrams	24
Dopamine in Fear Extinction	24
Nanoliposomes as a Therapeutic Tool for Alzheimer’s Disease	23
Procedures for Culturing and Genetically Manipulating Murine Hippocampal Postnatal Neurons	23
A Practical Guide to Using CV Analysis for Determining the Locus of Synaptic Plasticity	22
Taurine Promotes Neurite Outgrowth and Synapse Development of Both Vertebrate and Invertebrate Central Neurons	21
Multiple Roles of Actin in Exo- and Endocytosis	21
Voltage-Gated Ca2+ Channels in Dopaminergic Substantia Nigra Neurons: Therapeutic Targets for Neuroprotection in Parkinson's Disease?	21
Astrocytic Ephrin-B1 Controls Synapse Formation in the Hippocampus During Learning and Memory	20
Modeling the Shape of Synaptic Spines by Their Actin Dynamics	20
The Decade of Super-Resolution Microscopy of the Presynapse	20
The α5 Nicotinic Acetylcholine Receptor Subunit Differentially Modulates α4β2* and α3β4* Receptors	20

The Synaptic Extracellular Matrix: Long-Lived, Stable, and Still Remarkably Dynamic	20
Nano-Organization at the Synapse: Segregation of Distinct Forms of Neurotransmission	20
SynapsEM: Computer-Assisted Synapse Morphometry	19
The Non-receptor Tyrosine Kinase Pyk2 in Brain Function and Neurological and Psychiatric Diseases	19
From Synaptic Protein to Prion: The Long and Controversial Journey of α-Synuclein	19
The Yin and Yang of GABAergic and Glutamatergic Synaptic Plasticity: Opposites in Balance by Crosstalking Mechanisms	18
Maturation of Heterogeneity in Afferent Synapse Ultrastructure in the Mouse Cochlea	18
The Renin–Angiotensin System Modulates Dopaminergic Neurotransmission: A New Player on the Scene	18
Calcium signaling in astrocytes and gliotransmitter release	18
Histone Deacetylase 6 and the Disease Mechanisms of α-Synucleinopathies	16
Synaptic Density and Neuronal Metabolic Function Measured by Positron Emission Tomography in the Unilateral 6-OHDA Rat Model of Parkinson’s Disease	16
Current Therapies for Neonatal Hypoxic–Ischaemic and Infection-Sensitised Hypoxic–Ischaemic Brain Damage	16
The Shaping of AMPA Receptor Surface Distribution by Neuronal Activity	16
Segregation of D1 and D2 dopamine receptors in the striatal direct and indirect pathways: An historical perspective	16
GluN2D NMDA Receptors Gate Fear Extinction Learning and Interneuron Plasticity	15
Microglia Heterogeneity in Alzheimer’s Disease: Insights From Single-Cell Technologies	15
Poly I:C Activated Microglia Disrupt Perineuronal Nets and Modulate Synaptic Balance in Primary Hippocampal Neurons in vitro	14
The Subcortical-Allocortical- Neocortical continuum for the Emergence and Morphological Heterogeneity of Pyramidal Neurons in the Human Brain	14
Neuronal Glycoprotein M6a: An Emerging Molecule in Chemical Synapse Formation and Dysfunction	14
Room for Two: The Synaptophysin/Synaptobrevin Complex	13
Excessive β-Catenin in Excitatory Neurons Results in Reduced Social and Increased Repetitive Behaviors and Altered Expression of Multiple Genes Linked to Human Autism	13
Ocular Hypertension Drives Remodeling of AMPA Receptors in Select Populations of Retinal Ganglion Cells	13
Multi-Electrode Array Analysis Identifies Complex Dopamine Responses and Glucose Sensing Properties of Substantia Nigra Neurons in Mouse Brain Slices	13
Dorsal-Ventral Differences in Modulation of Synaptic Transmission in the Hippocampus	13
Parvalbumin Interneurons and Perineuronal Nets in the Hippocampus and Retrosplenial Cortex of Adult Male Mice After Early Social Isolation Stress and Perinatal NMDA Receptor Antagonist Treatment	13
Glucagon-like peptide 1 and glucose-dependent insulinotropic peptide hormones and novel receptor agonists protect synapses in Alzheimer’s and Parkinson’s diseases	13
Targeting prefrontal cortex GABAergic microcircuits for the treatment of alcohol use disorder	12
Calcium Sensors STIM1 and STIM2 Regulate Different Calcium Functions in Cultured Hippocampal Neurons	12
Dendritic and Spine Heterogeneity of von Economo Neurons in the Human Cingulate Cortex	12
cAMP-Dependent Synaptic Plasticity at the Hippocampal Mossy Fiber Terminal	11
Autaptic Cultures: Methods and Applications	11
Molecular mechanisms of synaptogenesis	11
GRIN2B-related neurodevelopmental disorder: current understanding of pathophysiological mechanisms	11
Disposition of Proteins and Lipids in Synaptic Membrane Compartments Is Altered in Q175/Q7 Huntington’s Disease Mouse Striatum	11
The Requirement of the C-Terminal Domain of GluA1 in Different Forms of Long-Term Potentiation in the Hippocampus Is Age-Dependent	11
Endocannabinoid-Like Lipid Neuromodulators in the Regulation of Dopamine Signaling: Relevance for Drug Addiction	10
Cell-Type-Specific Adaptions in Striatal Medium-Sized Spiny Neurons and Their Roles in Behavioral Responses to Drugs of Abuse	10
Transient Enhanced GluA2 Expression in Young Hippocampal Neurons of a Fragile X Mouse Model	10
Organization of Presynaptic Autophagy-Related Processes	10
Orexin-A/Hypocretin-1 Controls the VTA-NAc Mesolimbic Pathway via Endocannabinoid-Mediated Disinhibition of Dopaminergic Neurons in Obese Mice	10
Synaptic Vesicle Recycling and the Endolysosomal System: A Reappraisal of Form and Function	9
Palmitoylated Proteins in Dendritic Spine Remodeling	9
Invaginating Structures in Synapses – Perspective	9
Correlative Assembly of Subsynaptic Nanoscale Organizations During Development	9
Two Distinct Populations of α1α6-Containing GABAA-Receptors in Rat Cerebellum	9
Endocannabinoid Modulation of Nucleus Accumbens Microcircuitry and Terminal Dopamine Release	9
Adenosine A1 Receptor-Mediated Synaptic Depression in the Developing Hippocampal Area CA2	9
Reducing Glutamate Uptake in Rat Hippocampal Slices Enhances Astrocytic Membrane Depolarization While Down-Regulating CA3–CA1 Synaptic Response	8
Dexmedetomidine and Ketamine Attenuated Neuropathic Pain Related Behaviors via STING Pathway to Induce ER-Phagy	8
SHANK3 Antibody Validation: Differential Performance in Western Blotting, Immunocyto- and Immunohistochemistry	8

NPY Released From GABA Neurons of the Dentate Gyrus Specially Reduces Contextual Fear Without Affecting Cued or Trace Fear	8
Glycinergic Transmission in the Presence and Absence of Functional GlyT2: Lessons From the Auditory Brainstem	8
Gelatinase Biosensor Reports Cellular Remodeling During Epileptogenesis	8
Myosin V Regulates Spatial Localization of Different Forms of Neurotransmitter Release in Central Synapses	8
Phenotypic Characterization and Brain Structure Analysis of Calcium Channel Subunit α2δ-2 Mutant (Ducky) and α2δ Double Knockout Mice	7
Jacob, a Synapto-Nuclear Protein Messenger Linking N-methyl-D-aspartate Receptor Activation to Nuclear Gene Expression	7
Perineuronal Net Receptor PTPσ Regulates Retention of Memories	7
Neurexins and their ligands at inhibitory synapses	7
Presynaptic Calcium Channel Open Probability and Changes in Calcium Influx Throughout the Action Potential Determined Using AP-Waveforms	7
AMPA Receptor Function in Hypothalamic Synapses	7
Chronic Presence of Oligomeric Aβ Differentially Modulates Spine Parameters in the Hippocampus and Cortex of Mice With Low APP Transgene Expression	7
Visualizing Synaptic Multi-Protein Patterns of Neuronal Tissue With DNA-Assisted Single-Molecule Localization Microscopy	7
Dendritic Voltage Recordings Explain Paradoxical Synaptic Plasticity: A Modeling Study	7
Alzheimer’s disease as a synaptopathy: Evidence for dysfunction of synapses during disease progression	7
Identification of Potential Interacting Proteins With the Extracellular Loops of the Neuronal Glycoprotein M6a by TMT/MS	7
Cannabinoid Modulation of Dopamine Release During Motivation, Periodic Reinforcement, Exploratory Behavior, Habit Formation, and Attention	7
Synaptic determinants of cholinergic interneurons hyperactivity during parkinsonism	6
Wnt Signaling Through Nitric Oxide Synthase Promotes the Formation of Multi-Innervated Spines	6
Intracellular Properties of Deep-Layer Pyramidal Neurons in Frontal Eye Field of Macaque Monkeys	6
Early-Occurring Dendritic Spines Alterations in Mouse Models of Alzheimer’s Disease Inform on Primary Causes of Neurodegeneration	6
Spindle-Shaped Neurons in the Human Posteromedial (Precuneus) Cortex	6
Striatal Synapse Degeneration and Dysfunction Are Reversed by Reactivation of Wnt Signaling	6
Contribution of Membrane Lipids to Postsynaptic Protein Organization	6
Selective Recruitment of Presynaptic and Postsynaptic Forms of mGluR-LTD	6
Light Sheet Illumination for 3D Single-Molecule Super-Resolution Imaging of Neuronal Synapses	6
Resilient Hippocampal Gamma Rhythmogenesis and Parvalbumin-Expressing Interneuron Function Before and After Plaque Burden in 5xFAD Alzheimer’s Disease Model	5
Neocortical layer 5 subclasses: From cellular properties to roles in behavior	5
Fear Memory Retrieval Is Associated With a Reduction in AMPA Receptor Density at Thalamic to Amygdala Intercalated Cell Synapses	5
Targeting Endocannabinoid Signaling in the Lateral Habenula as an Intervention to Prevent Mental Illnesses Following Early Life Stress: A Perspective	5
(M)Unc13s in Active Zone Diversity: A Drosophila Perspective	5
Reducing Auditory Nerve Excitability by Acute Antagonism of Ca2+-Permeable AMPA Receptors	5
Stereotactically Injected Kv1.2 and CASPR2 Antisera Cause Differential Effects on CA1 Synaptic and Cellular Excitability, but Both Enhance the Vulnerability to Pro-epileptic Conditions	5
Synaptoprotection in Perinatal Asphyxia: An Experimental Approach	5
Paternal Deprivation and Female Biparental Family Rearing Induce Dendritic and Synaptic Changes in Octodon degus: I. Medial Prefrontal Cortex	5
N-Oleoylglycine and N-Oleoylalanine Do Not Modify Tolerance to Nociception, Hyperthermia, and Suppression of Activity Produced by Morphine	5
Clmp Regulates AMPA and Kainate Receptor Responses in the Neonatal Hippocampal CA3 and Kainate Seizure Susceptibility in Mice	5
Effects of the clathrin inhibitor Pitstop-2 on synaptic vesicle recycling at a central synapse in vivo	5
The plasticity of cardiac sympathetic nerves and its clinical implication in cardiovascular disease	4
A Model for Predicting Cation Selectivity and Permeability in AMPA and NMDA Receptors Based on Receptor Subunit Composition	4
Output-Specific Adaptation of Habenula-Midbrain Excitatory Synapses During Cocaine Withdrawal	4
Dentate Granule Cells Are Hyperexcitable in the TgF344-AD Rat Model of Alzheimer's Disease	4
The biological alterations of synapse/synapse formation in sepsis-associated encephalopathy	4
Rethinking the network determinants of motor disability in Parkinson’s disease	4
Grand Challenge at the Frontiers of Synaptic Neuroscience	4
Selective Enrichment of Munc13-2 in Presynaptic Active Zones of Hippocampal Pyramidal Cells That Innervate mGluR1α Expressing Interneurons	4
Noise Exposure Potentiates Exocytosis From Cochlear Inner Hair Cells	4
Presynaptic Mitochondria Communicate With Release Sites for Spatio-Temporal Regulation of Exocytosis at the Motor Nerve Terminal	4
Quantitative Imaging With DNA-PAINT for Applications in Synaptic Neuroscience	4
Genetic Code Expansion and Click-Chemistry Labeling to Visualize GABA-A Receptors by Super-Resolution Microscopy	4
Latest updates on the serotonergic system in depression and anxiety	4
Cellular basis of learning and memory in the carotid body	4
Aberrant Synaptic PTEN in Symptomatic Alzheimer’s Patients May Link Synaptic Depression to Network Failure	4
A Picture Worth a Thousand Molecules—Integrative Technologies for Mapping Subcellular Molecular Organization and Plasticity in Developing Circuits	4
PKN1 Is a Novel Regulator of Hippocampal GluA1 Levels	4
Deletion of ErbB4 Disrupts Synaptic Transmission and Long-Term Potentiation of Thalamic Input to Amygdalar Medial Paracapsular Intercalated Cells	4