OOIR: Observatory of International Research

Papers

(The median citation count of Frontiers in Synaptic Neuroscience is 4. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-11-01 to 2024-11-01.)

Article	Citations
Semaphorins in Adult Nervous System Plasticity and Disease	70
Impact of Perineuronal Nets on Electrophysiology of Parvalbumin Interneurons, Principal Neurons, and Brain Oscillations: A Review	64
Calcium signaling in astrocytes and gliotransmitter release	39
Alzheimer’s disease as a synaptopathy: Evidence for dysfunction of synapses during disease progression	33
Voltage-Gated Ca2+-Channel α1-Subunit de novo Missense Mutations: Gain or Loss of Function – Implications for Potential Therapies	32
A Synaptic Framework for the Persistence of Memory Engrams	31
Dopamine in Fear Extinction	28
Multiple Roles of Actin in Exo- and Endocytosis	28
SynapsEM: Computer-Assisted Synapse Morphometry	27
The Non-receptor Tyrosine Kinase Pyk2 in Brain Function and Neurological and Psychiatric Diseases	26
The Shaping of AMPA Receptor Surface Distribution by Neuronal Activity	24
The Yin and Yang of GABAergic and Glutamatergic Synaptic Plasticity: Opposites in Balance by Crosstalking Mechanisms	24
Voltage-Gated Ca2+ Channels in Dopaminergic Substantia Nigra Neurons: Therapeutic Targets for Neuroprotection in Parkinson's Disease?	24
Nano-Organization at the Synapse: Segregation of Distinct Forms of Neurotransmission	23
The Synaptic Extracellular Matrix: Long-Lived, Stable, and Still Remarkably Dynamic	23
The Renin–Angiotensin System Modulates Dopaminergic Neurotransmission: A New Player on the Scene	22
The α5 Nicotinic Acetylcholine Receptor Subunit Differentially Modulates α4β2* and α3β4* Receptors	22
Segregation of D1 and D2 dopamine receptors in the striatal direct and indirect pathways: An historical perspective	21
GRIN2B-related neurodevelopmental disorder: current understanding of pathophysiological mechanisms	21
Cell-Type-Specific Adaptions in Striatal Medium-Sized Spiny Neurons and Their Roles in Behavioral Responses to Drugs of Abuse	20
Neuronal Glycoprotein M6a: An Emerging Molecule in Chemical Synapse Formation and Dysfunction	20
Maturation of Heterogeneity in Afferent Synapse Ultrastructure in the Mouse Cochlea	19
Current Therapies for Neonatal Hypoxic–Ischaemic and Infection-Sensitised Hypoxic–Ischaemic Brain Damage	19
cAMP-Dependent Synaptic Plasticity at the Hippocampal Mossy Fiber Terminal	19
Microglia Heterogeneity in Alzheimer’s Disease: Insights From Single-Cell Technologies	19

Glucagon-like peptide 1 and glucose-dependent insulinotropic peptide hormones and novel receptor agonists protect synapses in Alzheimer’s and Parkinson’s diseases	18
Multiple modulatory roles of serotonin in chronic pain and injury-related anxiety	18
Synaptic Density and Neuronal Metabolic Function Measured by Positron Emission Tomography in the Unilateral 6-OHDA Rat Model of Parkinson’s Disease	18
Room for Two: The Synaptophysin/Synaptobrevin Complex	17
The Subcortical-Allocortical- Neocortical continuum for the Emergence and Morphological Heterogeneity of Pyramidal Neurons in the Human Brain	17
Targeting prefrontal cortex GABAergic microcircuits for the treatment of alcohol use disorder	17
Parvalbumin Interneurons and Perineuronal Nets in the Hippocampus and Retrosplenial Cortex of Adult Male Mice After Early Social Isolation Stress and Perinatal NMDA Receptor Antagonist Treatment	17
GluN2D NMDA Receptors Gate Fear Extinction Learning and Interneuron Plasticity	16
Poly I:C Activated Microglia Disrupt Perineuronal Nets and Modulate Synaptic Balance in Primary Hippocampal Neurons in vitro	16
Neurexins and their ligands at inhibitory synapses	15
Calcium Sensors STIM1 and STIM2 Regulate Different Calcium Functions in Cultured Hippocampal Neurons	15
Glycinergic Transmission in the Presence and Absence of Functional GlyT2: Lessons From the Auditory Brainstem	15
Multi-Electrode Array Analysis Identifies Complex Dopamine Responses and Glucose Sensing Properties of Substantia Nigra Neurons in Mouse Brain Slices	14
Transient Enhanced GluA2 Expression in Young Hippocampal Neurons of a Fragile X Mouse Model	14
Molecular mechanisms of synaptogenesis	14
AMPA Receptor Function in Hypothalamic Synapses	13
Organization of Presynaptic Autophagy-Related Processes	12
SHANK3 Antibody Validation: Differential Performance in Western Blotting, Immunocyto- and Immunohistochemistry	12
Disposition of Proteins and Lipids in Synaptic Membrane Compartments Is Altered in Q175/Q7 Huntington’s Disease Mouse Striatum	12
Dexmedetomidine and Ketamine Attenuated Neuropathic Pain Related Behaviors via STING Pathway to Induce ER-Phagy	12
Correlative Assembly of Subsynaptic Nanoscale Organizations During Development	11
Genetic Code Expansion and Click-Chemistry Labeling to Visualize GABA-A Receptors by Super-Resolution Microscopy	11
Perineuronal Net Receptor PTPσ Regulates Retention of Memories	11
Endocannabinoid-Like Lipid Neuromodulators in the Regulation of Dopamine Signaling: Relevance for Drug Addiction	11
Synaptic Vesicle Recycling and the Endolysosomal System: A Reappraisal of Form and Function	11
Orexin-A/Hypocretin-1 Controls the VTA-NAc Mesolimbic Pathway via Endocannabinoid-Mediated Disinhibition of Dopaminergic Neurons in Obese Mice	11
Latest updates on the serotonergic system in depression and anxiety	10
Neocortical layer 5 subclasses: From cellular properties to roles in behavior	10
Metaplasticity framework for cross-modal synaptic plasticity in adults	10
Endocannabinoid Modulation of Nucleus Accumbens Microcircuitry and Terminal Dopamine Release	10
Contribution of Membrane Lipids to Postsynaptic Protein Organization	10
NPY Released From GABA Neurons of the Dentate Gyrus Specially Reduces Contextual Fear Without Affecting Cued or Trace Fear	10
Cannabinoid Modulation of Dopamine Release During Motivation, Periodic Reinforcement, Exploratory Behavior, Habit Formation, and Attention	9
Phenotypic Characterization and Brain Structure Analysis of Calcium Channel Subunit α2δ-2 Mutant (Ducky) and α2δ Double Knockout Mice	9
Light Sheet Illumination for 3D Single-Molecule Super-Resolution Imaging of Neuronal Synapses	9
The plasticity of cardiac sympathetic nerves and its clinical implication in cardiovascular disease	9
Jacob, a Synapto-Nuclear Protein Messenger Linking N-methyl-D-aspartate Receptor Activation to Nuclear Gene Expression	9
Resilient Hippocampal Gamma Rhythmogenesis and Parvalbumin-Expressing Interneuron Function Before and After Plaque Burden in 5xFAD Alzheimer’s Disease Model	9
Myosin V Regulates Spatial Localization of Different Forms of Neurotransmitter Release in Central Synapses	9
Synaptic determinants of cholinergic interneurons hyperactivity during parkinsonism	8
Invaginating Structures in Synapses – Perspective	8
Selective Recruitment of Presynaptic and Postsynaptic Forms of mGluR-LTD	8
Visualizing Synaptic Multi-Protein Patterns of Neuronal Tissue With DNA-Assisted Single-Molecule Localization Microscopy	8
Striatal Synapse Degeneration and Dysfunction Are Reversed by Reactivation of Wnt Signaling	8
Dendritic Voltage Recordings Explain Paradoxical Synaptic Plasticity: A Modeling Study	7
Spindle-Shaped Neurons in the Human Posteromedial (Precuneus) Cortex	7
Palmitoylation of A-kinase anchoring protein 79/150 modulates its nanoscale organization, trafficking, and mobility in postsynaptic spines	7
Intracellular Properties of Deep-Layer Pyramidal Neurons in Frontal Eye Field of Macaque Monkeys	7
Diverse organization of voltage-gated calcium channels at presynaptic active zones	6
Selective Enrichment of Munc13-2 in Presynaptic Active Zones of Hippocampal Pyramidal Cells That Innervate mGluR1α Expressing Interneurons	6

PKN1 Is a Novel Regulator of Hippocampal GluA1 Levels	6
Rethinking the network determinants of motor disability in Parkinson’s disease	6
Shared and divergent principles of synaptic transmission between cortical excitatory neurons in rodent and human brain	6
Dentate Granule Cells Are Hyperexcitable in the TgF344-AD Rat Model of Alzheimer's Disease	6
Editorial: Perineuronal Nets as Therapeutic Targets for the Treatment of Neuropsychiatric Disorders	6
Targeting Endocannabinoid Signaling in the Lateral Habenula as an Intervention to Prevent Mental Illnesses Following Early Life Stress: A Perspective	6
Reducing Auditory Nerve Excitability by Acute Antagonism of Ca2+-Permeable AMPA Receptors	6
N-Oleoylglycine and N-Oleoylalanine Do Not Modify Tolerance to Nociception, Hyperthermia, and Suppression of Activity Produced by Morphine	6
Blast-Induced Mild Traumatic Brain Injury Alterations of Corticotropin-Releasing Factor Neuronal Activity in the Mouse Hypothalamic Paraventricular Nucleus	6
Clmp Regulates AMPA and Kainate Receptor Responses in the Neonatal Hippocampal CA3 and Kainate Seizure Susceptibility in Mice	5
Membrane lipid rafts are required for AMPA receptor tyrosine phosphorylation	5
Grand Challenge at the Frontiers of Synaptic Neuroscience	5
A Model for Predicting Cation Selectivity and Permeability in AMPA and NMDA Receptors Based on Receptor Subunit Composition	5
Palmitoylation-regulated interactions of the pseudokinase calmodulin kinase-like vesicle-associated with membranes and Arc/Arg3.1	5
Genetic disorders of neurotransmitter release machinery	5
Cyclic AMP response element-binding protein (CREB) transcription factor in astrocytic synaptic communication	5
(M)Unc13s in Active Zone Diversity: A Drosophila Perspective	5
Different Synaptic Plasticity After Physiological and Psychological Stress in the Anterior Insular Cortex in an Observational Fear Mouse Model	5
Analytical approaches to examine gamma-aminobutyric acid and glutamate vesicular co-packaging	5
The biological alterations of synapse/synapse formation in sepsis-associated encephalopathy	5
Fear Memory Retrieval Is Associated With a Reduction in AMPA Receptor Density at Thalamic to Amygdala Intercalated Cell Synapses	5
Effects of the clathrin inhibitor Pitstop-2 on synaptic vesicle recycling at a central synapse in vivo	5
Regulation of Inhibitory Signaling at the Receptor and Cellular Level; Advances in Our Understanding of GABAergic Neurotransmission and the Mechanisms by Which It Is Disrupted in Epilepsy	5
Cellular basis of learning and memory in the carotid body	5
Output-Specific Adaptation of Habenula-Midbrain Excitatory Synapses During Cocaine Withdrawal	5
Heightened sympathetic neuron activity and altered cardiomyocyte properties in spontaneously hypertensive rats during the postnatal period	5
Presynaptic Mitochondria Communicate With Release Sites for Spatio-Temporal Regulation of Exocytosis at the Motor Nerve Terminal	4
A Picture Worth a Thousand Molecules—Integrative Technologies for Mapping Subcellular Molecular Organization and Plasticity in Developing Circuits	4
Tonic activation of GABAB receptors via GAT-3 mediated GABA release reduces network activity in the developing somatosensory cortex in GAD67-GFP mice	4
High-Resolution Fluorescence Imaging Combined With Computer Simulations to Quantitate Surface Dynamics and Nanoscale Organization of Neuroligin-1 at Synapses	4
Enhanced Non-Associative Long-Term Potentiation in Immature Granule Cells in the Dentate Gyrus of Adult Rats	4
Activity-Dependent Modulation of Tonic GABA Currents by Endocannabinoids in Hirudo verbana	4
Noise Exposure Potentiates Exocytosis From Cochlear Inner Hair Cells	4
Healthy cardiac myocytes can decrease sympathetic hyperexcitability in the early stages of hypertension	4
Memory retrieval, reconsolidation, and extinction: Exploring the boundary conditions of post-conditioning cue exposure	4
Deletion of ErbB4 Disrupts Synaptic Transmission and Long-Term Potentiation of Thalamic Input to Amygdalar Medial Paracapsular Intercalated Cells	4
Vagally-mediated heart block after myocardial infarction associated with plasticity of epicardial neurons controlling the atrioventricular node	4
Patch-to-Seq and Transcriptomic Analyses Yield Molecular Markers of Functionally Distinct Brainstem Serotonin Neurons	4
Aberrant Synaptic PTEN in Symptomatic Alzheimer’s Patients May Link Synaptic Depression to Network Failure	4
Quantitative Imaging With DNA-PAINT for Applications in Synaptic Neuroscience	4
Nitric Oxide Regulates GluA2-Lacking AMPAR Contribution to Synaptic Transmission of CA1 Apical but Not Basal Dendrites	4