OOIR: Observatory of International Research

Papers

(The median citation count of Frontiers in Synaptic Neuroscience is 4. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-02-01 to 2025-02-01.)

Article	Citations
Somatostatin Neurons in the Mouse Pontine Nucleus Activate GABAA Receptor Mediated Synaptic Currents in Locus Coeruleus Neurons	70
Editorial: Brain serotonergic system	69
Fetal Neuroprotective Strategies: Therapeutic Agents and Their Underlying Synaptic Pathways	54
Towards a Comprehensive Optical Connectome at Single Synapse Resolution via Expansion Microscopy	54
Editorial: Subcellular computations and information processing	32
Metformin inhibits spontaneous excitatory postsynaptic currents in spinal dorsal cord neurons from paclitaxel-treated rats	31
Rapid sequential clustering of NMDARs, CaMKII, and AMPARs upon activation of NMDARs at developing synapses	28
Synaptic spinules are reliable indicators of excitatory presynaptic bouton size and strength and are ubiquitous components of excitatory synapses in CA1 hippocampus	28
A Multisubcellular Compartment Model of AMPA Receptor Trafficking for Neuromodulation of Hebbian Synaptic Plasticity	26
Discordant Effects of Cannabinoid 2 Receptor Antagonism/Inverse Agonism During Adolescence on Pavlovian and Instrumental Reward Learning in Adult Male Rats	26
Nano-Organization at the Synapse: Segregation of Distinct Forms of Neurotransmission	25
Effects of the clathrin inhibitor Pitstop-2 on synaptic vesicle recycling at a central synapse in vivo	25
The Shaping of AMPA Receptor Surface Distribution by Neuronal Activity	24
Disposition of Proteins and Lipids in Synaptic Membrane Compartments Is Altered in Q175/Q7 Huntington’s Disease Mouse Striatum	24
Age-related changes in olivocochlear efferent innervation in gerbils	23
Inhibitory hippocampus-medial septum projection controls locomotion and exploratory behavior	23
Editorial: Latest Advances on Excitatory Synapse Biology	22
Deletion of ErbB4 Disrupts Synaptic Transmission and Long-Term Potentiation of Thalamic Input to Amygdalar Medial Paracapsular Intercalated Cells	21
Poly I:C Activated Microglia Disrupt Perineuronal Nets and Modulate Synaptic Balance in Primary Hippocampal Neurons in vitro	21
Molecular mechanisms of synaptogenesis	20
The short-term plasticity of VIP interneurons in motor cortex	20
Targeting Endocannabinoid Signaling in the Lateral Habenula as an Intervention to Prevent Mental Illnesses Following Early Life Stress: A Perspective	19
Cryo-EM tomography and automatic segmentation delineate modular structures in the postsynaptic density	19
Enhanced Non-Associative Long-Term Potentiation in Immature Granule Cells in the Dentate Gyrus of Adult Rats	18
Bringing synapses into focus: Recent advances in synaptic imaging and mass-spectrometry for studying synaptopathy	18

Nitric Oxide Regulates GluA2-Lacking AMPAR Contribution to Synaptic Transmission of CA1 Apical but Not Basal Dendrites	18
Intracellular Properties of Deep-Layer Pyramidal Neurons in Frontal Eye Field of Macaque Monkeys	17
Blast-Induced Mild Traumatic Brain Injury Alterations of Corticotropin-Releasing Factor Neuronal Activity in the Mouse Hypothalamic Paraventricular Nucleus	17
Organization of Presynaptic Autophagy-Related Processes	17
Rethinking the network determinants of motor disability in Parkinson’s disease	17
Striatal Synapse Degeneration and Dysfunction Are Reversed by Reactivation of Wnt Signaling	16
Glucagon-like peptide 1 and glucose-dependent insulinotropic peptide hormones and novel receptor agonists protect synapses in Alzheimer’s and Parkinson’s diseases	16
Serotonin as a volume transmission signal in the “simple nervous system” of mollusks: From axonal guidance to behavioral orchestration	15
Neurexins and their ligands at inhibitory synapses	15
The calcineurin regulator Sarah enables distinct forms of homeostatic plasticity at the Drosophila neuromuscular junction	14
Calcium signaling in astrocytes and gliotransmitter release	14
Glycinergic Transmission in the Presence and Absence of Functional GlyT2: Lessons From the Auditory Brainstem	14
Light Sheet Illumination for 3D Single-Molecule Super-Resolution Imaging of Neuronal Synapses	13
Cyclic AMP response element-binding protein (CREB) transcription factor in astrocytic synaptic communication	12
Maturation of Heterogeneity in Afferent Synapse Ultrastructure in the Mouse Cochlea	12
Semaphorins in Adult Nervous System Plasticity and Disease	12
Editorial: Synaptopathies: from bench to bedside	11
Memory retrieval, reconsolidation, and extinction: Exploring the boundary conditions of post-conditioning cue exposure	11
Dexmedetomidine and Ketamine Attenuated Neuropathic Pain Related Behaviors via STING Pathway to Induce ER-Phagy	11
Protein phosphatase-1 inhibitor-2 promotes PP1γ positive regulation of synaptic transmission	11
cAMP-Dependent Synaptic Plasticity at the Hippocampal Mossy Fiber Terminal	11
Spindle-Shaped Neurons in the Human Posteromedial (Precuneus) Cortex	10
Dynamics of Neuromuscular Transmission Reproduced by Calcium-Dependent and Reversible Serial Transitions in the Vesicle Fusion Complex	10
Killer or helper? The mechanism underlying the role of adenylate activated kinase in sound conditioning	10
Editorial: New insights into synaptic plasticity in fear conditioning	10
Myosin V Regulates Spatial Localization of Different Forms of Neurotransmitter Release in Central Synapses	10
Membrane lipid rafts are required for AMPA receptor tyrosine phosphorylation	10
Neocortical layer 5 subclasses: From cellular properties to roles in behavior	9
Dichotomic Hippocampal Transcriptome After Glutamatergic vs. GABAergic Deletion of the Cannabinoid CB1 Receptor	9
Synaptic Density and Neuronal Metabolic Function Measured by Positron Emission Tomography in the Unilateral 6-OHDA Rat Model of Parkinson’s Disease	9
Differential modulation of collybistin conformational dynamics by the closely related GTPases Cdc42 and TC10	9
Fear Memory Retrieval Is Associated With a Reduction in AMPA Receptor Density at Thalamic to Amygdala Intercalated Cell Synapses	9
Microglia Heterogeneity in Alzheimer’s Disease: Insights From Single-Cell Technologies	9
GRIN2B-related neurodevelopmental disorder: current understanding of pathophysiological mechanisms	9
The biological alterations of synapse/synapse formation in sepsis-associated encephalopathy	8
Genetic Code Expansion and Click-Chemistry Labeling to Visualize GABA-A Receptors by Super-Resolution Microscopy	8
Correlative Live-Cell and Super-Resolution Imaging to Link Presynaptic Molecular Organisation With Function	8
Editorial: Plasticity of inhibitory cells in health and disease	8
Editorial: Molecular Nanomachines of the Presynaptic Terminal, Volume II	8
Mechanisms Underlying Mu Opioid Receptor Effects on Parallel Fiber-Purkinje Cell Synaptic Transmission in Mouse Cerebellar Cortex	8
Selective Recruitment of Presynaptic and Postsynaptic Forms of mGluR-LTD	7
High-Resolution Fluorescence Imaging Combined With Computer Simulations to Quantitate Surface Dynamics and Nanoscale Organization of Neuroligin-1 at Synapses	7
Voltage-Gated Ca2+-Channel α1-Subunit de novo Missense Mutations: Gain or Loss of Function – Implications for Potential Therapies	6
Editorial: Dendritic Spines: From Biophysics to Neuropathology	6
The effect of single-cell knockout of Fragile X Messenger Ribonucleoprotein on synaptic structural plasticity	6
Editorial: Structural and quantitative modeling of synapses	6
Triose-phosphate isomerase deficiency is associated with a dysregulation of synaptic vesicle recycling in Drosophila melanogaster	6
Cellular Strategies for Frequency-Dependent Computation of Interaural Time Difference	6
Identification of Synaptic DGKθ Interactors That Stimulate DGKθ Activity	6
Editorial: Signaling mechanisms of synapse assembly	6

Cell-autonomous and differential endocannabinoid signaling impacts the development of presynaptic retinal ganglion cell axon connectivity in vivo	6
Visualizing Presynaptic Active Zones and Synaptic Vesicles	6
Editorial: Perineuronal Nets as Therapeutic Targets for the Treatment of Neuropsychiatric Disorders	6
Cell-Type-Specific Adaptions in Striatal Medium-Sized Spiny Neurons and Their Roles in Behavioral Responses to Drugs of Abuse	5
Quantitative Imaging With DNA-PAINT for Applications in Synaptic Neuroscience	5
Visualizing the triheteromeric N-methyl-D-aspartate receptor subunit composition	5
Distinctive biophysical features of human cell-types: insights from studies of neurosurgically resected brain tissue	5
Heightened sympathetic neuron activity and altered cardiomyocyte properties in spontaneously hypertensive rats during the postnatal period	5
The Wingless planar cell polarity pathway is essential for optimal activity-dependent synaptic plasticity	5
Genetic disorders of neurotransmitter release machinery	5
Editorial: Horizons in synaptic neuroscience	5
Orexin-A/Hypocretin-1 Controls the VTA-NAc Mesolimbic Pathway via Endocannabinoid-Mediated Disinhibition of Dopaminergic Neurons in Obese Mice	5
Five Hours Total Sleep Deprivation Does Not Affect CA1 Dendritic Length or Spine Density	5
Synaptic determinants of cholinergic interneurons hyperactivity during parkinsonism	5
Jacob, a Synapto-Nuclear Protein Messenger Linking N-methyl-D-aspartate Receptor Activation to Nuclear Gene Expression	5
A review of the mechanisms underlying the role of the GIPC3 gene in hereditary deafness	5
Healthy cardiac myocytes can decrease sympathetic hyperexcitability in the early stages of hypertension	5
Effect of Unilateral Acoustic Trauma on Neuronal Firing Activity in the Inferior Colliculus of Mice	5
Alzheimer’s disease as a synaptopathy: Evidence for dysfunction of synapses during disease progression	5
Modification of the synaptic cleft under excitatory conditions	5
PKN1 Is a Novel Regulator of Hippocampal GluA1 Levels	4
AMPA Receptor Function in Hypothalamic Synapses	4
Astrocyte: A Foe or a Friend in Intellectual Disability-Related Diseases	4
Editorial: NMDA receptors in physiology and disease	4
Corrigendum: Correlative Live-Cell and Super-Resolution Imaging to Link Presynaptic Molecular Organisation With Function	4
Tonic activation of GABAB receptors via GAT-3 mediated GABA release reduces network activity in the developing somatosensory cortex in GAD67-GFP mice	4
The Non-receptor Tyrosine Kinase Pyk2 in Brain Function and Neurological and Psychiatric Diseases	4
Editorial: Neuroprotection in Synaptic Signalling During Neurological Disorders	4
Editorial: Activated Synapses	4
NPY Released From GABA Neurons of the Dentate Gyrus Specially Reduces Contextual Fear Without Affecting Cued or Trace Fear	4
A tribute to Dr. Akira Yoshii, MD, PhD	4
Multiple modulatory roles of serotonin in chronic pain and injury-related anxiety	4
Unraveling Functional Diversity of Cortical Synaptic Architecture Through the Lens of Population Coding	4
Hearing Loss Increases Inhibitory Effects of Prefrontal Cortex Stimulation on Sound Evoked Activity in Medial Geniculate Nucleus	4