OOIR: Observatory of International Research

Papers

(The median citation count of Journal of Innate Immunity is 4. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-05-01 to 2025-05-01.)

Article	Citations
Human Ribonuclease 6 Has a Protective Role during Experimental Urinary Tract Infection	97
Expansion of Phenotypically Altered Dendritic Cell Populations in the Small Airways and Alveolar Parenchyma in Patients with Chronic Obstructive Pulmonary Disease	46
Obituary of Prof. Uli Theopold, 1957–2023	28
Regulation of TLR10 Expression and Its Role in Chemotaxis of Human Neutrophils	27
Metabolism Shapes Immune Responses to <i>Staphylococcus aureus</i>	25
Mechanisms and Therapeutic Strategies for MAFLD Targeting TLR4 Signaling Pathways	24
Type I interferon, induced by adenovirus or adenoviral vector infection, regulates the cytokine response to LPS in a macrophage type-specific manner	23
Murine Ribonuclease 6 Limits Bacterial Dissemination During Experimental Urinary Tract Infection	22
Macrophage-Biomimetic Nanoparticles Ameliorate Ulcerative Colitis through Reducing Inflammatory Factors Expression	21
Innate Immune Training with Bacterial Extracts Enhances Lung Macrophage Recruitment to Protect from Betacoronavirus Infection	20
<i>Ehrlichia chaffeensis</i> Co-Opts Phagocytic Hemocytes for Systemic Dissemination in the Lone Star Tick, <i>Amblyomma americanum</i>	20
Broad Ultrastructural and Transcriptomic Changes Underlie the Multinucleated Giant Hemocyte Mediated Innate Immune Response against Parasitoids	18
Farewell to Professors Arne Egesten and Heiko Herwald	18
Human Blood Non-Classical/Classical Monocyte Cells Are Heterogeneously Presented in Severe COVID-19 and Correlate with Disease Activity	17
Activation of NLRP3 Inflammasome Complexes by Beta-Tricalcium Phosphate Particles and Stimulation of Immune Cell Migration in vivo	17
Streptococcus pyogenes Activates Human Platelets via Streptolysin S-Mediated Calcium Ion Influx	16
The Role of Ficolins in Lung Injury	15
Time- and Stimulus-Dependent Characteristics of Innate Immune Cells in Organ-Cultured Human Corneal Tissue	15
Pro-Inflammatory of PRDM1/SIRT2/NLRP3 Axis in Monosodium Urate-Induced Acute Gouty Arthritis	13
GDF15 Suppresses Lymphoproliferation and Humoral Autoimmunity in a Murine Model of Systemic Lupus Erythematosus	13
Acknowledgement to Reviewers	13
<b><i>Streptococcus pneumoniae</i></b> Impairs Maturation of Human Dendritic Cells and Consequent Activation of CD4<sup>+</sup> T Cells via Pneumolysin	13
CLIPA7 Exhibits Pleiotropic Roles in the <b><i>Anopheles gambiae</i></b> Immune Response	12
Complex Thrombo-Inflammatory Responses versus Outcomes of Non-COVID-19 Community-Acquired Pneumonia and COVID-19	12
Lipoteichoic Acids Are Essential for Pneumococcal Colonization and Membrane Integrity	12

NFκB1 Dichotomously Regulates Pro-Inflammatory and Antiviral Responses in Asthma	12
Perilipin 1 Deficiency Prompts Lipolysis in Lipid Droplets and Aggravates the Pathogenesis of Persistent Immune Activation in <i>Drosophila</i>	12
YTHDC1-Modified m6A Methylation of Hsa_circ_0102678 Promotes Keratinocyte Inflammation Induced by <i>Cutibacterium acnes</i> Biofilm through Regulating miR-146a/TRAF6 and IRAK1 Axis	11
N6-Methyladenosine (m6A) Modification in Natural Immune Cell-Mediated Inflammatory Diseases	11
Tollip Inhibits IL-33 Release and Inflammation in Influenza A Virus-Infected Mouse Airways	10
The Gene Signature of Activated M-CSF-Primed Human Monocyte-Derived Macrophages Is IL-10-Dependent	10
The Role of Neutrophil in COVID-19 — Positive or Negative	10
miR-142-5p Encapsulated by Serum-Derived Extracellular Vesicles Protects against Acute Lung Injury in Septic Rats following Remote Ischemic Preconditioning via the PTEN/PI3K/Akt Axis	10
Unraveling the Complex Nexus of Macrophage Metabolism, Periodontitis, and Associated Comorbidities	10
Combined Heterozygous Genetic Variations in Complement C2 and C8B: An Explanation for Multidimensional Immune Imbalance?	10
Glyceraldehyde-3-Phosphate Dehydrogenase Binds with Spike Protein and Inhibits the Entry of SARS-CoV-2 into Host Cells	9
Vitamin D Enhances Neutrophil Generation and Function in Zebrafish (<b><i>Danio rerio</i></b>)	9
IRF1 Is Required for MDA5 (IFIH1) Induction by IFN-α, LPS, and poly(I:C) in Murine Macrophages	9
Increase in the Complement Activation Product C4d and the Terminal Complement Complex sC5b-9 Is Associated with Disease Severity and a Fatal Outcome in Necrotizing Soft-Tissue Infection	9
Interleukin-33 Ameliorates Murine Systemic Lupus Erythematosus and Is Associated with Induction of M2 Macrophage Polarisation and Regulatory T Cells	8
The Novel Inducer of Innate Immunity HO53 Stimulates Autophagy in Human Airway Epithelial Cells	8
Dysregulation of TLR Signaling-Associated Gene Expression in X-linked Agammaglobulinemia: Implications for Correlations Genotype-Phenotype and Disease Expression	8
<b><i>Porphyromonas gingivalis</i></b> Gingipains-Mediated Degradation of Plasminogen Activator Inhibitor-1 Leads to Delayed Wound Healing Responses in Human Endothelial Cells	8
Yin and Yang of Biofilm Formation and Cyclic di-GMP Signaling of the Gastrointestinal Pathogen <b><i>Salmonella enterica</i></b> Serovar Typhimurium	8
Development and characterization of novel ELISAs for the specific quantification of the factor H-related proteins 2, 3, 4 and 5	8
Dysregulated Immunometabolism Is Associated with the Generation of Myeloid-Derived Suppressor Cells in <b><i>Staphylococcus aureus</i></b> Chronic Infection	8
TLR10: An intriguing Toll-like receptor with many unanswered questions	8
KDM6A Lysine Demethylase Directs Epigenetic Polarity of MDSCs during Murine Sepsis	8
The Dynamics of Circulating Heparin-Binding Protein: Implications for Its Use as a Biomarker	8
Interference with Lipoprotein Maturation Sensitizes Methicillin-Resistant <b><i>Staphylococcus aureus</i></b> to Human Group IIA-Secreted Phospholipase A<sub>2</sub>	8
Erratum	8
Does Adenosine Triphosphate via Purinergic Receptor Signalling Fuel Pulmonary Fibrosis?	7
Acinetobacter baumannii Clinical Isolates Resist Complement-Mediated Lysis by Inhibiting the Complement Cascade and Improperly Depositing MAC	7
<b><i>Candida</i></b> Administration Worsens Neutrophil Extracellular Traps in Renal Ischemia Reperfusion Injury Mice: An Impact of Gut Fungi on Acute Kidney Injury	7
Development, Characterization, and in vivo Validation of a Humanized C6 Monoclonal Antibody that Inhibits the Membrane Attack Complex	7
Analyzing the Role of Specific Damage-Associated Molecular Patterns-Related Genes in Osteoarthritis and Investigating the Association between β-Amyloid and Apolipoprotein E Isoforms	7
Ste20-Like Kinase TAOK1 Positively Regulates Antiviral Responses by Controlling the TBK1-IRF3 Signaling Axis	7
Tryptophol Acetate and Tyrosol Acetate, Small-Molecule Metabolites Identified in a Probiotic Mixture, Inhibit Hyperinflammation	6
Emerging Roles of cGAS-STING Signaling in Mediating Ocular Inflammation	6
Cathelicidins Induce Toll-Interacting Protein Synthesis to Prevent Apoptosis in Colonic Epithelium	6
C-Terminal PEGylation Improves SAAP-148 Peptide’s Immunomodulatory Activities	6
CAPN1 Promotes Pseudomonas aeruginosa-Induced Infection by Interacting with TFEB and Inhibiting Autophagy	6
Procoagulant Activity of Blood and Microvesicles Is Disturbed by Pneumococcal Pneumolysin, Which Interacts with Coagulation Factors	6
RNA Viruses, Toll-Like Receptors, and Cytokines: The Perfect Storm?	6
C4b-Binding Protein and Factor H Attenuate NLRP3 Inflammasome-Mediated Signalling Response during Group A Streptococci Infection in Human Cells	6
Lectin Pathway Enzyme MASP-2 and Downstream Complement Activation in COVID-19	5
Role of Lectin-like oxidized low-density lipoprotein receptor-1 (LOX-1) in inflammation and pathogen-associated interactions	5
Ex vivo and in vitro Monocyte Responses Do Not Reflect in vivo Immune Responses and Tolerance	5
Impact of Changes in Human Airway Epithelial Cellular Composition and Differentiation on SARS-CoV-2 Infection Biology	5
Pattern-Recognition Receptors and Immunometabolic Reprogramming: What We Know and What to Explore	5
Prediction of Respiratory Failure and Mortality in COVID-19 Patients Using Long Pentraxin PTX3	5
Degradation of Ubiquitin-Editing Enzyme A20 following Autophagy Activation Promotes RNF168 Nuclear Translocation and NF-κB Activation in Lupus Nephritis	5
Ras-Related Protein Rab5a Regulates Complement C5a Receptor Trafficking, Chemotaxis, and Chemokine Secretion in Human Macrophages	5
Development of a C3 Humanized Rat as a New Model for Evaluating Novel C3 Inhibitors	5
Formyl Peptide Receptor Type 2 Deficiency in Myeloid Cells Amplifies Sepsis-Induced Cardiac Dysfunction	4

TLR7 Activation in M-CSF-Dependent Monocyte-Derived Human Macrophages Potentiates Inflammatory Responses and Prompts Neutrophil Recruitment	4
TLR2 and NLRP3 Orchestrate Regulatory Roles in Escherichia coli Infection-Induced Septicemia in Mouse Models	4
Erratum	4
Histamine Produced by Gram-Negative Bacteria Impairs Neutrophil’s Antimicrobial Response by Engaging the Histamine 2 Receptor	4
Stat3 Regulates Developmental Hematopoiesis and Impacts Myeloid Cell Function via Canonical and Non-Canonical Modalities	4
Mesenchymal Stromal Cells Facilitate Neutrophil-Trained Immunity by Reprogramming Hematopoietic Stem Cells	4
Bruton’s Tyrosine Kinase in Neutrophils Is Crucial for Host Defense against <b><i>Klebsiella pneumoniae</i></b>	4
Biomarkers in Chronic Obstructive Pulmonary Disease: Emerging Roles of Eosinophils and Procalcitonin	4
TLR9 dependent activation by inactivated parapoxvirus ovis (iPPVO) in murine bone marrow-derived dendritic cells is associated with specific strain-dependent dendritic cell subsets	4