OOIR: Observatory of International Research

Papers

(The median citation count of Journal of Innate Immunity is 3. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-08-01 to 2026-08-01.)

Article	Citations
Compartment-Specific NK Cell Phenotypes Reveal Distinct Maturation and Activation States in Inflammatory Arthritis	61
Obituary of Prof. Uli Theopold, 1957–2023	47
Expansion of Phenotypically Altered Dendritic Cell Populations in the Small Airways and Alveolar Parenchyma in Patients with Chronic Obstructive Pulmonary Disease	30
The small ubiquitin-like modifier SUMO-3 acts as a neutrophil chemoattractant via the chemokine receptors CXCR1 and CXCR2	28
Mechanisms of Differential Signal Transduction by Interferon Lambda Receptor 1 Variants	26
Human Ribonuclease 6 Has a Protective Role during Experimental Urinary Tract Infection	25
Type I interferon, induced by adenovirus or adenoviral vector infection, regulates the cytokine response to LPS in a macrophage type-specific manner	23
Pharmacological Stimulator of Interferon Genes Activation Enhances Autophagy-Mediated Clearance of Mycobacterium tuberculosis in Human Macrophages	21
Mechanisms and Therapeutic Strategies for MAFLD Targeting TLR4 Signaling Pathways	20
Neutrophil CEACAMs and the inflammatory response to Neisseria gonorrhoeae	19
Metabolism Shapes Immune Responses to <i>Staphylococcus aureus</i>	18
Differential Recognition of Lipopolysaccharide O-Antigens by the Pattern Recognition Molecules Mannan-Binding Lectin and Ficolins of the Complement System	17
Macrophages in Ulcerative Colitis: Immunomodulatory Roles, Phenotypic Switching, and Therapeutic Targeting	17
Clodronate Liposomes Untangle the Role of Hemocytes in Apis mellifera Response to Temperature Variation and Microbial Infection	17
Interleukin-6 Limits Host Susceptibility to Urinary Tract Infection by Promoting Urothelial Expulsion of Intracellular Bacteria	17
Characterization of the Cellular Immune Response to Group B Streptococcal Vaginal Colonization	16
Murine Ribonuclease 6 Limits Bacterial Dissemination During Experimental Urinary Tract Infection	16
Neutrophil Inflammasome Activation and Pyroptosis Induced by a Metalloproteinase via HIF-1α and Gasdermin D Pathways	15
Editors’ Choice 2025 Journal of Innate Immunity: From Receptor Proximal Training to Metabolic and Fibrotic Control	15
Human Blood Non-Classical/Classical Monocyte Cells Are Heterogeneously Presented in Severe COVID-19 and Correlate with Disease Activity	15
Streptococcus pyogenes Activates Human Platelets via Streptolysin S-Mediated Calcium Ion Influx	14
Neutrophil Heterogeneity after Myocardial Infarction	14
<i>Ehrlichia chaffeensis</i> Co-Opts Phagocytic Hemocytes for Systemic Dissemination in the Lone Star Tick, <i>Amblyomma americanum</i>	14
Prior Exposure of Airway Epithelial Cells to Mycobacteria Reduces Subsequent Mycobacterium tuberculosis Infection and Resulting Inflammation	14
The Role of Ficolins in Lung Injury	13

Pro-Inflammatory of PRDM1/SIRT2/NLRP3 Axis in Monosodium Urate-Induced Acute Gouty Arthritis	13
Acknowledgement to Reviewers	13
Perilipin 1 Deficiency Prompts Lipolysis in Lipid Droplets and Aggravates the Pathogenesis of Persistent Immune Activation in <i>Drosophila</i>	12
CLIPA7 Exhibits Pleiotropic Roles in the <b><i>Anopheles gambiae</i></b> Immune Response	12
Complex Thrombo-Inflammatory Responses versus Outcomes of Non-COVID-19 Community-Acquired Pneumonia and COVID-19	12
YTHDC1-Modified m6A Methylation of Hsa_circ_0102678 Promotes Keratinocyte Inflammation Induced by <i>Cutibacterium acnes</i> Biofilm through Regulating miR-146a/TRAF6 and IRAK1 Axis	11
In vivo cytokine adsorption reveals distinct neutrophil mobilization pathways during experimental human endotoxemia	11
Lipoteichoic Acids Are Essential for Pneumococcal Colonization and Membrane Integrity	11
N6-Methyladenosine (m6A) Modification in Natural Immune Cell-Mediated Inflammatory Diseases	11
Combined Heterozygous Genetic Variations in Complement C2 and C8B: An Explanation for Multidimensional Immune Imbalance?	10
The Role of Interleukin-1 Receptor-Associated Kinase M in Pulmonary Diseases: Mechanisms and Therapeutic Implications	10
Target-Based Biofilm Inhibition and Antibiotic Enhancement Strategy by MiR.101.3p Using DNA Tetrahedrons	10
The Role of Neutrophil in COVID-19 — Positive or Negative	10
Unraveling the Complex Nexus of Macrophage Metabolism, Periodontitis, and Associated Comorbidities	10
IRF1 Is Required for MDA5 (IFIH1) Induction by IFN-α, LPS, and poly(I:C) in Murine Macrophages	9
Dysregulation of TLR Signaling-Associated Gene Expression in X-linked Agammaglobulinemia: Implications for Correlations Genotype-Phenotype and Disease Expression	9
Erratum	9
Pyroptosis Regulated by N6-Methyladenosine Modification: Implications for Pyroptosis-Related Disease Therapy	9
Glyceraldehyde-3-Phosphate Dehydrogenase Binds with Spike Protein and Inhibits the Entry of SARS-CoV-2 into Host Cells	9
Interleukin-33 Ameliorates Murine Systemic Lupus Erythematosus and Is Associated with Induction of M2 Macrophage Polarisation and Regulatory T Cells	9
TLR10: An intriguing Toll-like receptor with many unanswered questions	9
Ste20-Like Kinase TAOK1 Positively Regulates Antiviral Responses by Controlling the TBK1-IRF3 Signaling Axis	8
Interactions of Probiotics with the Immune Cells of Patients with COVID-19 Pneumonia	8
Development and Characterization of Novel ELISAs for the Specific Quantification of the Factor H-Related Proteins 2, 3, 4, and 5	8
Interference with Lipoprotein Maturation Sensitizes Methicillin-Resistant <b><i>Staphylococcus aureus</i></b> to Human Group IIA-Secreted Phospholipase A<sub>2</sub>	8
sCD126 as An Independent Prognostic Biomarker in Critical COVID-19	7
Acinetobacter baumannii Clinical Isolates Resist Complement-Mediated Lysis by Inhibiting the Complement Cascade and Improperly Depositing MAC	6
Oxidative Stress and Chronic Inflammation as Partners in Crime in Interstitial Cystitis/Bladder Pain Syndrome	6
Patients Hospitalized with COVID-19 Demonstrate Distinct Plasma Cytokine and Chemokine Concentrations in vivo and TLR-Mediated Cytokine and Chemokine Production in Whole Blood in vitro	6
Association of CD32-131H>R Polymorphism with End-Stage Chronic Obstructive Pulmonary Disease and Interstitial Lung Diseases	5
C4b-Binding Protein and Factor H Attenuate NLRP3 Inflammasome-Mediated Signalling Response during Group A Streptococci Infection in Human Cells	5
Tryptophol Acetate and Tyrosol Acetate, Small-Molecule Metabolites Identified in a Probiotic Mixture, Inhibit Hyperinflammation	5
RNA Viruses, Toll-Like Receptors, and Cytokines: The Perfect Storm?	5
CAPN1 Promotes Pseudomonas aeruginosa-Induced Infection by Interacting with TFEB and Inhibiting Autophagy	5
Impact of Adenosine Triphosphate Synthase Subunit β on TLR Signaling Pathway in Promoting Airway Remodeling and Heterogeneity of Small Airway Epithelial Cells in Chronic Obstructive Pulmonary Disease	5
Identification of Immune Candidate Genes in Post-Sepsis Syndrome: Linking Innate Immunity to Long-Term Autoimmune Responses	5
Cathelicidins Induce Toll-Interacting Protein Synthesis to Prevent Apoptosis in Colonic Epithelium	5
Analyzing the Role of Specific Damage-Associated Molecular Patterns-Related Genes in Osteoarthritis and Investigating the Association between β-Amyloid and Apolipoprotein E Isoforms	5
Does Adenosine Triphosphate via Purinergic Receptor Signalling Fuel Pulmonary Fibrosis?	5
C-Terminal PEGylation Improves SAAP-148 Peptide’s Immunomodulatory Activities	5
TLR2 or TLR4 Stimulation Induces Transmembrane TNF-Driven Priming in Macrophages Which Results in Improved Clearance of a Subsequent Staphylococcus aureus Infection	5
Degradation of Ubiquitin-Editing Enzyme A20 following Autophagy Activation Promotes RNF168 Nuclear Translocation and NF-κB Activation in Lupus Nephritis	4
Ras-Related Protein Rab5a Regulates Complement C5a Receptor Trafficking, Chemotaxis, and Chemokine Secretion in Human Macrophages	4
Role of Lectin-like oxidized low-density lipoprotein receptor-1 (LOX-1) in inflammation and pathogen-associated interactions	4
TLR9 dependent activation by inactivated parapoxvirus ovis (iPPVO) in murine bone marrow-derived dendritic cells is associated with specific strain-dependent dendritic cell subsets	4
Impact of Changes in Human Airway Epithelial Cellular Composition and Differentiation on SARS-CoV-2 Infection Biology	4
Development of a C3 Humanized Rat as a New Model for Evaluating Novel C3 Inhibitors	4
Ex vivo and in vitro Monocyte Responses Do Not Reflect in vivo Immune Responses and Tolerance	4
Mesenchymal Stromal Cells Facilitate Neutrophil-Trained Immunity by Reprogramming Hematopoietic Stem Cells	4
Emerging Roles of cGAS-STING Signaling in Mediating Ocular Inflammation	4

Pattern-Recognition Receptors and Immunometabolic Reprogramming: What We Know and What to Explore	4
Acknowledgement to Reviewers	4
Stat3 Regulates Developmental Hematopoiesis and Impacts Myeloid Cell Function via Canonical and Non-Canonical Modalities	4
Erratum	3
Acknowledgement to Reviewers	3
Association of Vitamin D with Severity and Outcome of COVID-19: Clinical and Experimental Evidence	3
The inflammatory response induced by Aspergillus fumigatus conidia is dependent on complement activation - Insight from a whole blood model	3
Formyl Peptide Receptor Type 2 Deficiency in Myeloid Cells Amplifies Sepsis-Induced Cardiac Dysfunction	3
Circulating Plasmacytoid Dendritic Cells Are Numerically and Functionally Deficient in Trauma Patients	3
Smad2/3 Regulates IL-6R m6A Methylation through METTL3 to Influence Inflammatory Responses in Hemorrhoidal Disease	3
TLR2 and NLRP3 Orchestrate Regulatory Roles in Escherichia coli Infection-Induced Septicemia in Mouse Models	3
TLR7 Activation in M-CSF-Dependent Monocyte-Derived Human Macrophages Potentiates Inflammatory Responses and Prompts Neutrophil Recruitment	3
Interaction between Group 3 Innate Lymphoid Cells, Microbiota, and Intestinal Diseases: Mechanisms and Therapeutic Potential	3