OOIR: Observatory of International Research

Papers

(The median citation count of Journal of Innate Immunity is 3. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-11-01 to 2024-11-01.)

Article	Citations
Metabolic Regulation of Macrophage Activation	81
Intracellular and Extracellular Lipopolysaccharide Signaling in Sepsis: Avenues for Novel Therapeutic Strategies	77
Innate Immune Cells in the Adipose Tissue in Health and Metabolic Disease	65
Interleukin 8 Elicits Rapid Physiological Changes in Neutrophils That Are Altered by Inflammatory Conditions	64
The Role of Cell Metabolism in Innate Immune Memory	44
Novel Strategies to Target Mast Cells in Disease	40
The Role of Innate Immune Cells in Nonalcoholic Fatty Liver Disease	35
RNA Sequencing Reveals Diverse Functions of Amniotic Fluid Neutrophils and Monocytes/Macrophages in Intra-Amniotic Infection	25
Hydrogen Peroxide Is Crucial for NLRP3 Inflammasome-Mediated IL-1β Production and Cell Death in Pneumococcal Infections of Bronchial Epithelial Cells	24
BAM15, a Mitochondrial Uncoupling Agent, Attenuates Inflammation in the LPS Injection Mouse Model: An Adjunctive Anti-Inflammation on Macrophages and Hepatocytes	20
ESCAPE: An Open-Label Trial of Personalized Immunotherapy in Critically lll COVID-19 Patients	19
Prediction of Respiratory Failure and Mortality in COVID-19 Patients Using Long Pentraxin PTX3	19
Macrophage-Biomimetic Nanoparticles Ameliorate Ulcerative Colitis through Reducing Inflammatory Factors Expression	19
Immunometabolism: Where Immunology and Metabolism Meet	18
IL-1 Mediates Tissue-Specific Inflammation and Severe Respiratory Failure in COVID-19	17
Downregulation of miRNA-451a Promotes the Differentiation of CD4+ T Cells towards Th2 Cells by Upregulating ETS1 in Childhood Asthma	16
Innate Host Defense against <b><i>Klebsiella pneumoniae</i></b> and the Outlook for Development of Immunotherapies	14
Vitamin D Enhances Neutrophil Generation and Function in Zebrafish (<b><i>Danio rerio</i></b>)	14
The Two Formyl Peptide Receptors Differently Regulate GPR84-Mediated Neutrophil NADPH Oxidase Activity	14
The Route of Infection Influences the Contribution of Key Immunity Genes to Antibacterial Defense in <b><i>Anopheles gambiae</i></b>	14
The Gene Signature of Activated M-CSF-Primed Human Monocyte-Derived Macrophages Is IL-10-Dependent	13
Positive Feedback Loop of Long Noncoding RNA OASL-IT1 and Innate Immune Response Restricts the Replication of Zika Virus in Epithelial A549 Cells	13
HMGB1-Like Dorsal Switch Protein 1 Triggers a Damage Signal in Mosquito Gut to Activate Dual Oxidase via Eicosanoids	12
Innate Immune Training with Bacterial Extracts Enhances Lung Macrophage Recruitment to Protect from Betacoronavirus Infection	12
The Capsule of <b><i>Acinetobacter baumannii</i></b> Protects against the Innate Immune Response	12

Innate Immune Responses to RSV Infection Facilitated by OGG1, an Enzyme Repairing Oxidatively Modified DNA Base Lesions	12
Interactions between Macrophages and Biofilm during <i>Staphylococcus aureus</i>-Associated Implant Infection: Difficulties and Solutions	12
T-Cell Immune Imbalance in Rheumatoid Arthritis Is Associated with Alterations in NK Cells and NK-Like T Cells Expressing CD38	11
<b><i>Candida</i></b> Administration Worsens Neutrophil Extracellular Traps in Renal Ischemia Reperfusion Injury Mice: An Impact of Gut Fungi on Acute Kidney Injury	11
Mast Cell Tryptase Potentiates Neutrophil Extracellular Trap Formation	11
GDF15 Suppresses Lymphoproliferation and Humoral Autoimmunity in a Murine Model of Systemic Lupus Erythematosus	11
AhR Regulates Peptidoglycan-Induced Inflammatory Gene Expression in Human Keratinocytes	11
Dysregulated Immunometabolism Is Associated with the Generation of Myeloid-Derived Suppressor Cells in <b><i>Staphylococcus aureus</i></b> Chronic Infection	10
High Infiltration of CD68<sup>+</sup>/CD163<sup>−</sup> Macrophages Is an Adverse Prognostic Factor after Neoadjuvant Chemotherapy in Esophageal and Gastric Adenocarcinoma	10
<b><i>Porphyromonas gingivalis</i></b> Gingipains-Mediated Degradation of Plasminogen Activator Inhibitor-1 Leads to Delayed Wound Healing Responses in Human Endothelial Cells	10
Pacritinib Inhibition of IRAK1 Blocks Aberrant TLR8 Signalling by SARS-CoV-2 and HIV-1-Derived RNA	9
Intestinal Epithelial Cell-Derived CD83 Contributes to Regulatory T-Cell Generation and Inhibition of Food Allergy	9
The Role of Streptococcal Cell-Envelope Proteases in Bacterial Evasion of the Innate Immune System	8
SP1 Promotes HDAC4 Expression and Inhibits HMGB1 Expression to Reduce Intestinal Barrier Dysfunction, Oxidative Stress, and Inflammatory Response after Sepsis	8
Anti-Fibrotic Activity of an Antimicrobial Peptide in a <b><i>Drosophila</i></b> Model	8
C-Reactive Protein: More than a Biomarker	8
Impaired Degradation of Neutrophil Extracellular Traps: A Possible Severity Factor of Elderly Male COVID-19 Patients	7
Regulation of Macrophage Cell Surface GAPDH Alters LL-37 Internalization and Downstream Effects in the Cell	7
Ovalbumin-Induced Epithelial Activation Directs Monocyte-Derived Dendritic Cells to Instruct Type 2 Inflammation in T Cells Which Is Differentially Modulated by 2′-Fucosyllactose and 3-Fucosyllactose	7
Flagellin Alleviates Airway Allergic Response by Stabilizing Eosinophils through Modulating Oxidative Stress	7
TLR7 Ligation Inhibits TLR8 Responsiveness in IL-27-Primed Human THP-1 Monocytes and Macrophages	7
Yin and Yang of Biofilm Formation and Cyclic di-GMP Signaling of the Gastrointestinal Pathogen <b><i>Salmonella enterica</i></b> Serovar Typhimurium	7
MASP-1 and MASP-3 Bind Directly to <b><i>Aspergillus fumigatus</i></b> and Promote Complement Activation and Phagocytosis	7
Lectin Pathway Enzyme MASP-2 and Downstream Complement Activation in COVID-19	6
Serine Protease Networks Mediate Immune Responses in Extra-Embryonic Tissues of Eggs in the Tobacco Hornworm, <b><i>Manduca sexta</i></b>	6
Ras-Related Protein Rab5a Regulates Complement C5a Receptor Trafficking, Chemotaxis, and Chemokine Secretion in Human Macrophages	6
Emerging Roles of cGAS-STING Signaling in Mediating Ocular Inflammation	6
Mesenchymal Stromal Cells Facilitate Neutrophil-Trained Immunity by Reprogramming Hematopoietic Stem Cells	6
Activation of NLRP3 Inflammasome Complexes by Beta-Tricalcium Phosphate Particles and Stimulation of Immune Cell Migration in vivo	6
Broad Ultrastructural and Transcriptomic Changes Underlie the Multinucleated Giant Hemocyte Mediated Innate Immune Response against Parasitoids	6
Lipidomic Profiling of Bronchoalveolar Lavage Fluid Extracellular Vesicles Indicates Their Involvement in Lipopolysaccharide-Induced Acute Lung Injury	6
NFκB1 Dichotomously Regulates Pro-Inflammatory and Antiviral Responses in Asthma	5
Ex vivo and in vitro Monocyte Responses Do Not Reflect in vivo Immune Responses and Tolerance	5
Impact of Changes in Human Airway Epithelial Cellular Composition and Differentiation on SARS-CoV-2 Infection Biology	5
Inhibition of Piezo1 Ameliorates Intestinal Inflammation and Limits the Activation of Group 3 Innate Lymphoid Cells in Experimental Colitis	5
Association of Vitamin D with Severity and Outcome of COVID-19: Clinical and Experimental Evidence	5
Selected β-Glucans Act as Immune-Training Agents by Improving Anti-Mycobacterial Activity in Human Macrophages: A Pilot Study	5
TLR7 Activation in M-CSF-Dependent Monocyte-Derived Human Macrophages Potentiates Inflammatory Responses and Prompts Neutrophil Recruitment	5
<b><i>Streptococcus pneumoniae</i></b> Impairs Maturation of Human Dendritic Cells and Consequent Activation of CD4<sup>+</sup> T Cells via Pneumolysin	5
Role of Surfactant Protein D in Experimental Otitis Media	5
Time- and Stimulus-Dependent Characteristics of Innate Immune Cells in Organ-Cultured Human Corneal Tissue	5
The Citrullination-Neutrophil Extracellular Trap Axis in Chronic Diseases	5
Tollip Inhibits IL-33 Release and Inflammation in Influenza A Virus-Infected Mouse Airways	5
Formyl Peptide Receptor Type 2 Deficiency in Myeloid Cells Amplifies Sepsis-Induced Cardiac Dysfunction	5
Neuronal Dual Leucine Zipper Kinase Mediates Inflammatory and Nociceptive Responses in Cyclophosphamide-Induced Cystitis	5
Exosomes Transport Anti-Human Immunodeficiency Virus Factors from Human Cervical Epithelial Cells to Macrophages	5
Obesity Exacerbates Lupus Activity in Fc Gamma Receptor IIb Deficient Lupus Mice Partly through Saturated Fatty Acid-Induced Gut Barrier Defect and Systemic Inflammation	5
Mitochondrial Damage-Associated Molecular Patterns and Metabolism in the Regulation of Innate Immunity	5
miR-142-5p Encapsulated by Serum-Derived Extracellular Vesicles Protects against Acute Lung Injury in Septic Rats following Remote Ischemic Preconditioning via the PTEN/PI3K/Akt Axis	5
Helminth Antigen Exposure Enhances Early Immune Control of Mycobacterium tuberculosis in Monocytes and Macrophages	5

The Dynamics of Circulating Heparin-Binding Protein: Implications for Its Use as a Biomarker	4
Hypoxia-Inducible Factor 1 Alpha Is Dispensable for Host Defense of Group B <b><i>Streptococcus</i></b> Colonization and Infection	4
KDM6A Lysine Demethylase Directs Epigenetic Polarity of MDSCs during Murine Sepsis	4
TGF-β1 Inhibition of ACE2 Mediated by miRNA Uncovers Novel Mechanism of SARS-CoV-2 Pathogenesis	4
A Thermally Stable Protein EPP1 of Corn Borer <b><i>Ostrinia furnacalis</i></b> Regulates Hemocytic Encapsulation	4
Biomarkers in Chronic Obstructive Pulmonary Disease: Emerging Roles of Eosinophils and Procalcitonin	4
Calcineurin Aα Contributes to IgE-Dependent Mast-Cell Mediator Secretion in Allergic Inflammation	3
The Efficacy of Posttreatment with Synthetic C-Reactive Protein in Murine Bacterial Peritonitis via Activation of FcγRI-Expressing Kupffer Cells	3
Bone Marrow Mesenchymal Stem Cells Release miR-378a-5p-Carried Extracellular Vesicles to Alleviate Rheumatoid Arthritis	3
Basic Mechanisms of Immunometabolites in Shaping the Immune Response	3
Pro-Inflammatory of PRDM1/SIRT2/NLRP3 Axis in Monosodium Urate-Induced Acute Gouty Arthritis	3
C-Terminal PEGylation Improves SAAP-148 Peptide’s Immunomodulatory Activities	3
Metabolism Shapes Immune Responses to <i>Staphylococcus aureus</i>	3
Histamine Produced by Gram-Negative Bacteria Impairs Neutrophil’s Antimicrobial Response by Engaging the Histamine 2 Receptor	3
GSK3β Inhibition Prevents Macrophage Reprogramming by High-Dose Methotrexate	3
Activating Natural Killer Cell Receptors, Selectins, and Inhibitory Siglecs Recognize Ebolavirus Glycoprotein	3
Human Monocytes Exposed to SARS-CoV-2 Display Features of Innate Immune Memory Producing High Levels of CXCL10 upon Restimulation	3
Mannan-Binding Lectin Reduces Epithelial-Mesenchymal Transition in Pulmonary Fibrosis via Inactivating the Store-Operated Calcium Entry Machinery	3
Human STING Is Regulated by an Autoinhibitory Mechanism for Type I Interferon Production	3
<b><i>Staphylococcus aureus</i></b> Activates the Aryl Hydrocarbon Receptor in Human Keratinocytes	3