OOIR: Observatory of International Research

Papers

(The H4-Index of Frontiers in Molecular Neuroscience is 40. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-03-01 to 2024-03-01.)

Article	Citations
Targeting Oxidative Stress and Inflammation to Prevent Ischemia-Reperfusion Injury	220
CNS-Derived Blood Exosomes as a Promising Source of Biomarkers: Opportunities and Challenges	137
Neuroprotection Against Oxidative Stress: Phytochemicals Targeting TrkB Signaling and the Nrf2-ARE Antioxidant System	98
The P2X7 Receptor: Central Hub of Brain Diseases	86
Circulating Exosomal miRNA as Diagnostic Biomarkers of Neurodegenerative Diseases	86
Oxidative Stress in Cognitive and Epigenetic Aging: A Retrospective Glance	84
The Neuromuscular Junction in Health and Disease: Molecular Mechanisms Governing Synaptic Formation and Homeostasis	81
Cannabinoids, Endocannabinoids and Sleep	80
Functions of p38 MAP Kinases in the Central Nervous System	76
New Insights Into Drug Discovery Targeting Tau Protein	75
Targeting Amyloidogenic Processing of APP in Alzheimer’s Disease	73
Protocadherins at the Crossroad of Signaling Pathways	73
Tau Protein and Its Role in Blood–Brain Barrier Dysfunction	73
The Role of Neurod Genes in Brain Development, Function, and Disease	72
Methyltransferase 3 Mediated miRNA m6A Methylation Promotes Stress Granule Formation in the Early Stage of Acute Ischemic Stroke	70
SOX Transcription Factors as Important Regulators of Neuronal and Glial Differentiation During Nervous System Development and Adult Neurogenesis	64
Brain Derived Exosomes Are a Double-Edged Sword in Alzheimer’s Disease	59
Gut Metabolite TMAO Induces Synaptic Plasticity Deficits by Promoting Endoplasmic Reticulum Stress	57
MicroRNAs in Alzheimer’s Disease: Function and Potential Applications as Diagnostic Biomarkers	54
Degradation and Transmission of Tau by Autophagic-Endolysosomal Networks and Potential Therapeutic Targets for Tauopathy	53
Long Non-coding RNAs and Circular RNAs: Insights Into Microglia and Astrocyte Mediated Neurological Diseases	53
Protein Aggregation and Dysfunction of Autophagy-Lysosomal Pathway: A Vicious Cycle in Lysosomal Storage Diseases	53
Current Approaches for Glioma Gene Therapy and Virotherapy	53
Dysregulation of RNA-Binding Proteins in Amyotrophic Lateral Sclerosis	52
Insights Into the Role and Potential of Schwann Cells for Peripheral Nerve Repair From Studies of Development and Injury	52

LAMA2-Related Dystrophies: Clinical Phenotypes, Disease Biomarkers, and Clinical Trial Readiness	50
Anterograde Axonal Transport in Neuronal Homeostasis and Disease	50
Islet Amyloid Polypeptide: A Partner in Crime With Aβ in the Pathology of Alzheimer's Disease	48
Mitochondrial Extracellular Vesicles – Origins and Roles	48
Melatonin Act as an Antidepressant via Attenuation of Neuroinflammation by Targeting Sirt1/Nrf2/HO-1 Signaling	47
The Potential Value of Targeting Ferroptosis in Early Brain Injury After Acute CNS Disease	47
Profiling Microglia From Alzheimer’s Disease Donors and Non-demented Elderly in Acute Human Postmortem Cortical Tissue	46
Recent Developments in Data Independent Acquisition (DIA) Mass Spectrometry: Application of Quantitative Analysis of the Brain Proteome	45
The Role of P2X7 Receptor in Alzheimer’s Disease	44
Trace Amine-Associated Receptor 5 Provides Olfactory Input Into Limbic Brain Areas and Modulates Emotional Behaviors and Serotonin Transmission	44
Mouse Models of Alzheimer’s Disease	43
The Delta-Opioid Receptor; a Target for the Treatment of Pain	42
Metformin Protects From Rotenone–Induced Nigrostriatal Neuronal Death in Adult Mice by Activating AMPK-FOXO3 Signaling and Mitigation of Angiogenesis	42
NF-κB Inhibitors Attenuate MCAO Induced Neurodegeneration and Oxidative Stress—A Reprofiling Approach	41
Integrated Metabolomics and Proteomics Analysis Reveals Plasma Lipid Metabolic Disturbance in Patients With Parkinson’s Disease	41
Positive Allosteric Modulation of CB1 Cannabinoid Receptor Signaling Enhances Morphine Antinociception and Attenuates Morphine Tolerance Without Enhancing Morphine- Induced Dependence or Reward	40