Doklady Biochemistry and Biophysics

Article	Citations
Dipeptide Mimetics of Different NGF and BDNF Loops Activate PLC-γ1	21
Expressions of Pathogenesis related 1 (PR1) Gene in Solanum lycopersicum and Influence of Salicylic Acid Exposures on Host-Meloidogyne incognita Interactions	14
The Effect of Surgical Trauma in the Nasal Cavity on the Behavior in the Open Field and the Autonomic Nervous System of Rats	13
Novel pH-Sensitive Microbial Rhodopsin from Sphingomonas paucimobilis	13
Effects of Silicon Nanoparticles on Photosynthetic Pigments and Biogenic Elements in Tomato Plants Infected with Root-Knot Nematode Meloidogyne incognita	11
Influence of Surgical Trauma in the Nasal Cavity on the Expression of p53 Protein in the Hippocampus of Rats	9
Evaluation of Induced Apoptosis by Biosynthesized Zinc Oxide Nanoparticles in MCF-7 Breast Cancer Cells Using Bak1 and Bclx Expression	9
The Anxiolytic Effect of the Neuropeptide Cycloprolylglycine Is Mediated by AMPA and TrkB Receptors	9
Changes in the Time-Domain of Heart Rate Variability and Corticosterone after Surgical Trauma to the Nasal Septum in Rats	8
Peptide Blocker of Ion Channel TRPV1 Exhibits a Long Analgesic Effect in the Heat Stimulation Model	8
Low-Intensity Laser Therapy As a Method to Reduce Stress Responses after Septoplasty	8
New Thieno-[2,3-d]pyrimidine-Based Functional Antagonist for the Receptor of Thyroid Stimulating Hormone	8
Recombinant Analogue of the Human Protein SLURP-1 Inhibits the Growth of U251 MG and A172 Glioma Cells	8
Neuroprotective Potential of Peptides HFRWPGP (ACTH6–9PGP), KKRRPGP, and PyrRP in Cultured Cortical Neurons at Glutamate Excitotoxicity	8
Neuroprotective and Antioxidant Activity of Arachidonoyl Choline, Its Bis-Quaternized Analogues and Other Acylcholines	7
Effectiveness of the Sequential Use of Plastic and Titanium Implants for Experimental Replacement of the Mandibular Defect in Animals Using Preliminary Digital Design	7
The Structural–Functional Damage of Fibrinogen Oxidized by Hydrogen Peroxide	7
Epitope Analysis of Murine and Chimeric Monoclonal Antibodies Recognizing the Cancer Testis Antigen PRAME	7
Comparison of the Effects of Septoplasty and Sinus Lifting Simulation in Rats on Changes in Heart Rate Variability	7
Chemoprotective Effect of Daphnetin in Doxorubicin Treated Esophageal Cancer Stem Cell Xenograft Tumor Mouse	6
Exogenic Melatonin Reduces the Toxic Effect of Polymetallic Stress on Barley Plants	6
Melatonin Supports Photochemical Activity of Assimilation Apparatus and Delays Senescence of Leaves of Monocotyledonous Plants	6
Andrographolide Induces Apoptosis in Gastric Cancer Cells through Reactivation of p53 and Inhibition of Mdm-2	6
The Melatonin Receptor CAND2/PMTR1 Is Involved in the Regulation of Mitochondrial Gene Expression under Photooxidative Stress	6
Production of a Cloned Offspring and CRISPR/Cas9 Genome Editing of Embryonic Fibroblasts in Cattle	6

Punica granatum Extract Inhibits Bladder Cancer Cell Viability, Invasion and Migration through Down-Regulation of HOXD10 Signalling Pathway	6
Viscous Media Slow Down the Decay of the Key Intermediate in Bacterial Bioluminescent Reaction	6
Targeted Knockout of the dhfr, glul, bak1, and bax Genes by the Multiplex Genome Editing in CHO Cells	5
Delivery of Antibody-Like Molecules, Monobodies, Capable of Binding with SARS-CoV-2 Virus Nucleocapsid Protein, into Target Cells	5
Multifunctional Complexes Based on Photoluminescent Upconversion Nanoparticles for Theranostics of the HER2-Positive Tumors	5
Kinetics of Chemical Processes in the Human Brain. The Cholinergic Synapse—Mechanisms of Functioning and Control Methods	5
The BEAF-32 Protein Directly Interacts with Z4/putzig and Chriz/Chromator Proteins in Drosophila melanogaster	5
Immunosuppression Factors PD-1, PD-L1, and IDO1 and Colorectal Cancer	5
Blockers of Nicotinic Acetylcholine Receptors Delay Tumor Growth and Increase Antitumor Activity of Mouse Splenocytes	5
Antibodies to the N-Terminal Domain of Angiotensin-Converting Enzyme (ACE2) That Block Its Interaction with SARS-CoV-2 S Protein	5
Structural and Functional Diversification of SEPALLATA Genes TM5 and RIN in Tomato Species (Section Lycopersicon)	5
Morphological and Molecular-Biological Features of Inflammatory and Regeneratory Processes in Peridont Tissues with Periimplantitis and Periodontitis	5
Cytokine Production by Tumor Bioptate at Different Pathological Prognostic Stages in Breast Cancer	5
The Relationship between p53-Positive Neurons and Dark Neurons in the Hippocampus of Rats after Surgical Interventions on the Nasal Septum	5
Influence of Gold Nanoparticles on the Tolerance of Wheat to Low Temperature	4
Graphene Oxide Nanoparticels Interaction with Jurkat Cell Line in Cell-IQ System	4
Indirubin-3′-Oxime (IDR3O) Inhibits Proliferation of Osteosarcoma Cells in vitro and Tumor Growth in vivo Through AMPK-Activation and PGC-1α/TFAM Up-Regulation	4
Renal Tissue Damage Induced by Acute Kidney Injury in Sepsis Rat Model Is Inhibited by Cynaropicrin via IL-1β and TNF-α Down-Regulation	4
Stimulation of Ovulation in Immature Female Rats Using Orthosteric and Allosteric Luteinizing Hormone Receptor Agonists	4
Kinetics of Chemical Processes in the Human Brain. Proton Blockade of Acetylcholinesterase and pH-Impulse in the Mechanism of Functioning of the Cholinergic Synapse	4
Growth-Stimulating Activity of Natural Polymer-Based Nanocomposites of Selenium during the Germination of Cultivated Plant Seeds	4
The Effect of Low and Medium Doses of Proton Pencil Scanning Beam on the Blood-Forming Organs during Total Irradiation of Mice	4
Development of Low-Molecular-Weight Allosteric Agonist of Thyroid-Stimulating Hormone Receptor with Thyroidogenic Activity	4
The Center of Origin and Colonization Routes of Noble Salmons of the Genus Salmo (Salmonidae, Actinopterigii)	4
Synthetic Analogs of 6-Bromohypaphorine, a Natural Agonist of Nicotinic Acetylcholine Receptors, Reduce Cardiac Reperfusion Injury in a Rat Model of Myocardial Ischemia	3
Cognitive Enhancer Noopept Activates Transcription Factor HIF-1	3
Prostate Cancer Growth Inhibition by 1-(3,5-Dimethylphenyl)–6-methyl-1H-pyrazolo[4,3-c]pyridin-4(5H)-one via Down-regulation of Phosphorylation PI3K/AKT and STA3/JAK2	3
Differences in the Drosha and Dicer Cleavage Profiles in Colorectal Cancer and Normal Colon Tissue Samples	3
Cold Stress Activates the Expression of Genes of the Chloroplast Transcription Apparatus in Arabidopsis thaliana Plants	3
A Higher Level of Expression of the Nucleolar Protein SURF6 in Human Normal Activated Lymphocytes and in Lymphocytes of Patients with Lymphoproliferative Disorders	3
Neuronal Apoptosis Preventive Potential of Sophocarpine via Suppression of Aβ-Accumulation and Down-Regulation of Inflammatory Response	3
Relationship Estimation of Cell Mobility Proteins Level with Processes of Proteolysis and Lymphogenic Metastasis in Breast Cancer	3
Immortalization of Human Keratinocytes Using the Catalytic Subunit of Telomerase	3
Novel Negative Sense Genes in the RNA Genome of Coronaviruses	3
Factors Involved in miRNA Processing Change Its Expression Level during Imitation of Hypoxia in BeWo b30 Cells	3
A New Type of Light-Harvesting Complex Detected when Growing Rhodopseudomonas palustris under Low Light Intensity Conditions	3
Modular Nanotransporters Capable of Binding to SARS-CoV-2 Virus Nucleocapsid Protein in Target Cells	3
Bioprotective and Functional Effect of Carnosine on Sepsis Induced Renal Damage in Male Albino Rat Model through Targeting IL-1β and TNF-α Production	3
The First Dipeptide Mimetic of Neurotrofin-3: Design and Pharmacological Properties	3
Effect of Eriocitrin on Cell Proliferation, Apoptosis, Migration, and Scar Formation-Related Genes Expression in Tendon Stem Cells	3
Polymetallic Stress Changes the Endogenous Status of Brassinosteroids and Reduces the Effectiveness of Photochemical Reactions Photosystem II in Barley Plants	3
Study of the Interaction between Xmas-2, the Main Protein of TREX-2 mRNA Export Complex, and the Orc3 Protein, a Subunit of ORC Complex of D. melanogaster	3
Polyunsaturated Fatty Acid Content in Muscle Tissue Is Associated with the Duration of Embryo Development in Salmonoid Fishes (Salmonoidei)	3
GRUSP, an Universal Stress Protein, Is Involved in Gibberellin-dependent Induction of Flowering in Arabidopsis thaliana	3
Effect of the Entomopathogenic Fungus Beauveria bassiana on the Development of Faba Bean (Vicia faba) Diseases in the Field Conditions	3
Synergistic Effect of the Combined Action of Targeted and Photodynamic Therapy on HER2-Positive Breast Cancer	2
Phospholipid Composition of Fingerlings of Atlantic Salmon Salmo salar during Growth and Development in Aquaculture: The Effect of Different Lighting and Feeding Regimes	2
The Synthesis of Main Capsid Protein of Anogenital Type HPV6 L1 in Plant Expression System on the Basis of Tomato Fruits	2
Effect of Alpha-Fetoprotein on Differentiation of Myeloid Supressor Cells	2
Use of Genetically Encoded Fluorescent Aptamers for Visualization of Mycobacterium tuberculosis Small RNA MTS1338 in Infected Macrophages	2

Comparative Analysis of Long Noncoding RNA Expression in Human Hepatocyte Cell Lines and Liver	2
Selection of Laboratory Mice for the Cognitive Task Successful Solution and for the Inability to Solve It	2
On a Possible Way to Increase the Efficiency of Photosynthesis	2
The Recombinant Luciferase of the Fungus Neonothopanus nambi: Obtaining and Properties	2
Differences in Presentation of SARS-CoV-2 Omicron Strain Variant BA.1–BA.5 Peptides by HLA Molecules	2
Regulation of the Placental Renin-Angiotensin-Aldosterone System in Early- and Late-Onset Preeclampsia	2
Dioscorea deltoidea Leaf Extract (DDLE) Targets PI3K/AKT/mTOR Pathway and Inhibits Ovarian Cancer Cell Growth	2
Fatty Acid Composition of Yakut Horse Tissues	2
Expression of Protein Kinases RIPK-1 and RIPK-3 in Mouse and Human Hair Follicle	2
Scanning Optical Probe Nanotomography for Investigation of the Structure of Biomaterials and Cells	2
Comparison of Protective Reactions of Rape Seeds to Chloride Salination at Exposure to Epibrassinolide before or during Salt Stress	2
Preventive Effect of Saussurea lappa Extract on Osteoarthritis in Mice Model through Inhibition of NF-κB Pathway	2
Induction of Hypoxic Response in Caco-2 Cells Promote the Expression of Genes Involved in SARS-CoV-2 Endocytosis and Transcytosis	2
Method for Primary Screening of Pharmaceuticals on the Paramecium caudatum Eukaryotic Cell Model	2
Chlorophyll a Dimers Bound in the Water-Soluble Protein BoWSCP Photosensitize the Reduction of Cytochrome c	2
Effects of Silicon Nanoparticles on the Activity of Antioxidant Enzymes in Tomato Roots Invaded by Meloidogyne incognita (Kofoid et White, 1919) Chitwood, 1949	2
Expression of CASC8 RNA in Human Pancreatic Cancer Cell Lines	2
Protective Effect of Tubotaiwine on Cadmium-Induced Hypertension in Rats through Reduction in Arterial Stiffness and Vascular Remodeling	2
Boerhaavia diffusa Extract Acts as a Specific Antituberculosis Agent in Vitro Against Mycobacterium tuberculosis H37Rv Infection	2
Depolarization of the Rat Atria in Experimental Simulation of the Holiday Heart Syndrome	2
Deep Physical-Chemical Purification of Gas Medium in Artificial Ecosystems	2
Comparative Study of the Effect of Snake Venoms on the Growth of Ciliates Tetrahymena pyriformis: Identification of Venoms with High Antiprotozoal Activity	2
Content of Docosahexaenoic Acid in Pectoral Muscles of Birds Correlates with Wing Beat Frequency	2
Influence of Acoustic-Mechanical Impact on the Reproductive Qualities of Sturgeon Sperm during Cryopreservation	2
Among Antibody-Like Molecules, Monobodies, Able to Interact with Nucleocapsid Protein of SARS-CoV Virus, There Are Monobodies with High Affinity to Nucleocapsid Protein of SARS-CoV-2 Virus	2
The Role of 20-Hydroxyecdysone in the Control of Carbohydrate Levels in Drosophila melanogaster under Short-Term Heat Stress	2
Interchromosomal Contacts of rDNA Clusters in Three Human Cell Lines Are Associated with Silencing of Genes Controlling Morphogenesis	2
Increasing the Efficiency of Cytochrome P450 3A4 Electrocatalysis Using Electrode Modification with Spatially Ordered Anodic Aluminum Oxide-Based Nanostructures for Investigation of Metabolic Transfor	2
Temperature Dependence of Tryptophan Fluorescence Lifetime as an Indicator of Its Microenvironment Dynamics	2
Changes in the Microbiome of Milk in Cows with Mastitis	2
Atypical Acetylcholine Receptors on the Neurons of the Turkish Snail	2
Association of HLA Class I Genotype with Mortality in Patients with Diabetes Mellitus and COVID-19	2
Recruitment to Chromatin of (GA)n-Associated Factors GAF and Psq in the Transgenic Model System Depends on the Presence of Architectural Protein Binding Sites	2
The Effect of Polymetallic Pollution on Ion-Exchange Properties of Barley Root and Shoot Cell Walls	2
Chemical Induction of Trophoblast Hypoxia by Cobalt Chloride Leads to Increased Expression of DDIT3	2
Synthesis and Anti-influenza Activity of Vinylphosphonic Acid (Co)polymers	2
Selection of an Amino Acid Site with One of the Fastest Cleavage Kinetics by the Endosomal Protease Cathepsin B for Potential Use in Drug Delivery Systems	1
Dioscorea deltoidea Leaf Extract (DDLE) Attenuates Cisplatin-Induced Ovarian Injury via Regulation of Oxidative Stress	1
Properties and Activity of Peptide Derivatives of ACE2 Cellular Receptor and Their Interaction with SARS-CoV-2 S Protein Receptor-Binding Domain	1
Inhibition of the c-Myc Oncogene by the Aureolic Acid Group Antibiotics	1
Plant Ploidy Level and the Presence of Cadmium in the Growing Environment Changes the Content of the Main Components of the Phenolic Complex in Buckwheat Sprouts	1
Ontogenetic, Light, and Circadian Regulation of PAP Protein Genes during Seed Germination of Arabidopsis thaliana	1
Adaptation to Antimicrobials and Pathogenicity in Mycoplasmas: Development of Ciprofloxacin-Resistance and Evolution of Virulence in Acholeplasma laidlawii	1
The Xmas-2 Protein of Drosophila melanogaster Undergoes Cleavage into Two Fragments	1
Rational Design and Mutagenesis of Fungal Luciferase from Neonothopanus nambi	1
Paraphyly of the Pipistrelles (Pipistrellus; Vespertilionidae) is Confirmed by the Analysis of the Nuclear Gene Markers	1
Influence of Internal and External Factors on the Production of Cytokines by Peripheral Blood Cells in Breast Cancer	1
Influence of HLDF Differentiation Factor on Nonspecific Invasive Breast Carcinoma in vitro	1
Effect of Anesthesia on Postoperative Pain in Patients after Septoplasty	1
The Expression Pattern and Clinical Significance of Lysyl Oxidase Family in Gliomas	1
Prognostic of Yield of Potatoes of Promising Domestic Varieties under the Impact of Stress Abiotic Factors	1
A New Technology for Recovery of Locomotion in Patients after a Stroke	1
Abutilon indicum Exhibits Anxiolytic and Antidepressant Effects in Mice Models	1
Structure of the Brain of the Smallest Coleoptera	1
Localization of Mechanisms of Amplitude–Frequency Modulation of Pulse Blood Perfusion of the Soft Tissue Microvasculature. Pilot Study	1
Combined Effect of Neutron and Proton Radiations on the Growth of Solid Ehrlich Ascites Carcinoma and Remote Effects in Mice	1
Study of the in Vivo Functional Role of Mutations in the BTB Domain of the CP190 Protein of Drosophila melanogaster	1
MLE Helicase Is a New Participant in the Transcription Regulation of the ftz-f1 Gene Encoding Nuclear Receptor in Higher Eukaryotes	1
Blood Plasma Lipoproteids: Oxidizability and Participation in the Transport of Acylhydroperoxy-Derivatives of Phospholipids	1
Synthesis of Deuterium-Labeled Pyrrolylcarnosine	1
Reusable System for Phenol Detection in an Aqueous Medium Based on Nanodiamonds and Extracellular Oxidase from Basidiomycete Neonothopanus nambi	1
Isotope Composition of Nitrogen and Stoichiometric Ratios of Elements in Biomass of Spirogyra in Lake Baikal	1
Fatty Acids Distribution in Seston, Tissues, and Faecal Pellets of Blue Mussels Mytilus edulis L.	1
The Variable CTCF Site from Drosophila melanogaster Ubx Gene is Redundant and Has no Insulator Activity	1
TTK Isoforms Interact with Two Regions of the Mep-1 Protein of Drosophila melanogaster	1
Differential Expression of Bipotent Commitment-Related Genes in Multipotent Mesenchymal Stromal Cells at Different O2 Levels	1
The Transcription Factor HY5 Is Involved in the Cytokinin-Dependent Regulation of the Expression of Genes Encoding Proteins Associated with Bacterial Plastid RNA-Polymerase during De-Etiolation of Ara	1
Study of the Role of Hearing Aid on the Area of the Acoustic Field of Vowels	1
Identification of Significant RNA-Binding Proteins in the Process of CD44 Splicing Using the Boosted Beta Regression Algorithm	1
Intracellular Delivery of an Antibody-Like Molecule Capable of Inhibiting c-Myc	1
Differentiation of IMR32 Neuroblastoma Is Accompanied by a Global Change in the Transcriptome	1
Nanosized Anti-Stokes Phosphors for Antitumor Drug Delivery and Solid Tumor Theranostics	1
Peroxide-Induced Damage to Plasminogen Molecules	1
The Effects of P53 in the Globular Heads of the C1q Receptor in Gastric Carcinoma Cell Apoptosis Are Exerted via a Mitochondrial-Dependent Pathway	1
Neuroprotective Effect of the Neuropeptide Cycloprolylglycine Depends on AMPA- and TrkB-Receptor Activation	1
Recombinant Fragment of the Extracellular Domain of Human Desmoglein 3 Fused with the Fc-Fragment of Human IgG1 Selectively Adsorbs Autoreactive Antibodies from the Sera of Pemphigus Patients	1
Finding the Light Emission Stimulator of Neonothopanus nambi Basidiomycete and Studying Its Properties	1
Influence of the Cultivation Conditions of the Glioblastoma Neurosphere on the Expression of MALAT1 and LINCROR Long Non-coding RNA Genes	1
Influence of Acrylamide on Energy Status and Survival of Bacteria of Different Systematic Groups	1
The Prognostic Significance of Spliceosomal Proteins for Patients with Glioblastoma	1

Synthesis of Fluorine-Containing Analogues of Purine Deoxynucleosides: Optimization of Enzymatic Transglycosylation Conditions	1
Ipomoea staphylina Attenuates Potassium Dichromate-Induced Nephrotoxicity in Wistar Rats via Antioxidant and Antiapoptotic Effects	1
Antagonists D1 and D2 of Dopamine Receptors Determine Different Mechanisms of Neuroprotective Action in the Frog Vestibular	1
Modulation of Calcium-Activated Chloride Currents in Rat Neurons with New 2-Aminotiophene-3-Carboxylic Acid Derivatives	1
Differences in Fatty Acid Composition between Orb-Weaver Spiders Inhabiting a Riparian Zone and a Steppe Are Associated with the Consumption of Different Chironomid Taxa	1
Study of the N-Terminal Domain Homodimerization in Human Proteins with Zinc Finger Clusters	1
Anxiolytic Effect of Peptides from Sea Anemone Heteractis crispa, Modulators of TRPV1 and ASIC Channels	1
Prenatal Stress and Adaptive Behavior of Offspring: The Role of Placental Serotonin	1
Topological Features of Histone H2A Monoubiquitination	1
PARP1 Gene Knockout Suppresses Expression of DNA Base Excision Repair Genes	1
Participation of Nitric Oxide in the Realization of Hemostatic Effects of Glyproline Peptides	1
The Use of the Antigenic Protein HPV6 L1 to Induce the Synthesis of Interferon, CD4 and CD8 T Lymphocytes, and Granzyme B in Blood and Splenocytes of Mice in Order to Develop a Broad Vaccine against A	1
Upconversion Nanoparticles Decorated with Polysialic Acid for Solid Tumors Visualization In Vivo	1
Computer Modeling of N-Acetylglutamate Synthase: From Primary Structure to Elemental Stages of Catalysis	1
Effect of Hypochlorite- and Peroxide-Induced Oxidation of Fibrinogen on the Fibrin Structure	1
Inhibition of Liver Cancer Cell Growth by Triethylsilyl Resveratrol through Targeting Phosphoinositide-3 Kinase Pathway	1
Osteosarcoma Cell Growth Inhibition by Isoxanthanol-Nanoparticles through Histone H3 Lysine 27 Trimethylation Downregulation and AMPK Activation	1
GSK3 Kinase Inhibitor, CHIR, Suppress Transcription of Tissue Specific POU2F1 Isoform in Burkitt Namalwa Lymphoma Cells	1
Three-Dimensional Printed BGS Treat a Large Bone Defect in a Rabbit Model	1
Assessment of Malondialdehyde Belonging to Modulators and Substrates of the P-Glycoprotein Transporter Protein	1
Fluorescence Excitation Spectra of Total Lipids with Paramagnetic Properties Isolated from Marine Organisms	1
Assessment of the Relative Biological Efficiency of Pencil Beam Scanning of Protons in Mice in Vivo	1
Inhibition of Histone Deacetylases 4 and 5 Reduces Titin Proteolysis and Prevents Reduction of TTN Gene Expression in Atrophied Rat Soleus Muscle after Seven-Day Hindlimb Unloading	1
Synthesis of 1-[ω-(Bromophenoxy)alkyl]-3-Naphthalenylmethyl Uracil Derivatives and Their Analogues as Probable Inhibitors of Human Cytomegalovirus Replication	1
Interactome of Paraoxonase PON2 Reveals New Pathways for Tumor Growth Regulation	1
Accumulation of β-Amyloid Leads to a Decrease in Lynx1 and Lypd6B Expression in the Hippocampus and Increased Expression of Proinflammatory Cytokines in the Hippocampus and Blood Serum	1
Basic Fibroblast Growth Factor Blockade Leads to Distinct Cellular Responses in Melanoma B16 Cells	1
New Sea Anemone Toxin RTX-VI Selectively Modulates Voltage-Gated Sodium Channels	1
Effect of Silicon Dioxide Nanoparticles on Syrian Hamsters Infected by Opisthorchis felineus: 1H MRS Study of the Brain	1
Are the Goals of Therapy Achievable in Patients with Rheumatoid Arthritis Receiving Upadacitinib in Real Clinical Practice?	1
Indolyl- and Pyrrolylazine Derivatives Cause the Accumulation of Heat Shock Protein Hsp70 in Sh-Sy5Y Human Neuroblastoma Cells	1
The Nature of Resistance of the Coagulation Factor XIII Structure to Hypochlorite-Induced Oxidation	1
Induction of Proline Iminopeptidase by Nitric Oxide May Result in the Proline Accumulation in the Pea Roots	1
Variability and Phylogeny of the Pepper Phytoene Synthase Paralogs PSY1 and PSY2 in Species of Various Capsicum Complexes	1
Influence of Tyrosyl-DNA Phosphodiesterase 1 Inhibitor on the Proapoptotic and Genotoxic Effects of Anticancer Agent Topotecan	1