OOIR: Observatory of International Research

Papers

(The median citation count of Hereditas is 1. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-05-01 to 2025-05-01.)

Article	Citations
Insulin-like growth factor binding protein 2: a core biomarker of left ventricular dysfunction in dilated cardiomyopathy	38
A novel chromatin regulator-related immune checkpoint related gene prognostic signature and potential candidate drugs for endometrial cancer patients	26
Upregulation of CENPM is associated with poor clinical outcome and suppression of immune profile in clear cell renal cell carcinoma	22
Extracellular vesicle-derived TP53BP1, CD34, and PBX1 from human peripheral blood serve as potential biomarkers for the assessment and prediction of vascular aging	20
Comprehensive evaluations of individual discrimination, kinship analysis, genetic relationship exploration and biogeographic origin prediction in Chinese Dongxiang group by a 60-plex DIP panel	19
E2F1-driven EXOSC10 transcription promotes hepatocellular carcinoma growth and stemness: a potential therapeutic target	19
LncRNA WAC-AS1 expression in human tumors correlates with immune infiltration and affects prognosis	19
An 8-gene predicting survival model of hepatocellular carcinoma (HCC) related to pyroptosis and cuproptosis	17
Mediating Mendelian randomization in the proteome identified potential drug targets for obesity-related allergic asthma	16
Enhancer analysis of the Drosophila zinc finger transcription factor Earmuff by gene targeting	15
An artificial neural network model based on autophagy-related genes in childhood systemic lupus erythematosus	15
Cell-free DNA from plasma as a promising alternative for detection of gene mutations in patients with Maffucci syndrome	14
Regulation of DNA methylation on key parasitism genes of Cysticercus cellulosae revealed by integrative epigenomic-transcriptomic analyses	13
Gene expression trend changes in breast cancer populations over two decades: insights from The Cancer Genome Atlas database	12
Comprehensive analysis to identify pseudogenes/lncRNAs-hsa-miR-200b-3p-COL5A2 network as a prognostic biomarker in gastric cancer	12
A cuproptosis-related lncRNA signature for predicting prognosis and immunotherapy response of lung adenocarcinoma	11
Stable populations and Hardy-Weinberg equilibrium	11
Network analysis of potential risk genes for psoriasis	10
A guide to barley mutants	10
Exploring the anticancer potential of green synthesized Zn/Cu nanocomposites from olive leaves against lung cancer	9
RNA-Seq based transcriptome analysis in oral lichen planus	9
The causal effects between low back pain and cerebrospinal fluid metabolites: a two-sample Mendelian randomization study	9
Susceptibility genes of hyperuricemia and gout	9
CircCENPM serves as a CeRNA to aggravate nasopharyngeal carcinoma metastasis and stemness via enhancing BMI1	9
Enhancer-driven transcription of MCM8 by E2F4 promotes ATR pathway activation and glioma stem cell characteristics	9

Favorable function of Ectonucleoside triphosphate diphosphohydrolase 1 high expression in thyroid carcinoma	9
MiR−33 as a novel diagnostic biomarker for distinguishing cholesterol from adenomatous polyps: a case-control study	9
Modulating the bicoid gradient in space and time	8
SREBF1, a target gene of multiple sclerosis and coronary heart disease: based on mendelian randomization study	8
Identification and validation of CDC20 and ITCH as ubiquitination related biomarker in idiopathic pulmonary fibrosis	8
The causal relationships between gut microbiota and venous thromboembolism: a Mendelian randomization study	7
Dynamic co-expression modular network analysis in nonalcoholic fatty liver disease	7
Exploring the mechanism of dendrobine in treating metabolic associated fatty liver disease based on network pharmacology and experimental validation	7
Revisiting bicoid function: complete inactivation reveals an additional fundamental role in Drosophila egg geometry specification	6
Identification of N6-methyladenosine-associated ferroptosis biomarkers in cervical cancer	6
Integrated multi-omics analysis and machine learning refine molecular subtypes and clinical outcome for hepatocellular carcinoma	6
Genetic analysis of albinism caused by compound heterozygous mutations of the OCA2 gene in a Chinese family	6
m6A transferase KIAA1429 mediates the upregulation of LncRNA LINC00968 promoting the progression of gastric cancer cells	6
Mechanisms of Cynarine for treatment of non-alcoholic fatty liver disease based on the integration of network pharmacology, molecular docking and cell experiment	6
Hsa_circ_0006006 is a potential biomarker for prognosis and cisplatin resistance in non-small cell lung cancer	5
Fine construction of gene coexpression network analysis using GTOM and RECODE detected a critical module of neuroblastoma stages 4 and 4S	5
Association between chronic obstructive pulmonary disease and osteoporosis: Mendelian randomization combined with bibliometric analysis	5
Investigating the clinical significance of OAS family genes in breast cancer: an in vitro and in silico study	5
The novel circFKBP8/miR-432-5p/E2F7 cascade functions as a regulatory network in breast cancer	5
Correction to: Performance comparison of four types of target enrichment baits for exome DNA sequencing	5
A bioinformatics analysis of the target role of miRNA-431-5p on KLK6 in colorectal cancer	5
The mechanism of Weiqi decoction treating gastric cancer: a work based on network pharmacology and experimental verification	4
Identification of fatty acid metabolism-related genes in the tumor microenvironment of breast cancer by a development and validation of prognostic index signature	4
Erianin inhibits the progression of DDP-resistant lung adenocarcinoma by regulating the Wnt/β-catenin pathway and activating the caspase-3 for apoptosis in vitro and in vivo	4
Disulfidptosis classification of pancreatic carcinoma reveals correlation with clinical prognosis and immune profile	4
Effects of fourteen essential minerals and vitamins on acute and chronic tubulointerstitial nephritis: a multivariate Mendelian randomization study	4
EZH2 regulates pancreatic cancer cells through E2F1, GLI1, CDK3, and Mcm4	4
Genetic insights into therapeutic targets for gout: evidence from a multi-omics mendelian randomization study	4
Circular RNAs: novel noncoding players in male infertility	4
Serum vitamin C levels and risk of osteoporosis: results from a cross-sectional study and Mendelian randomization analysis	4
Role of necroptosis and immune infiltration in essential thrombocytosis	4
Yi Gong San inhibits tumor immune escape by sensitizing colorectal cancer stem cells via the NF-κB pathway	4
γ-tocotrienol regulates gastric cancer by targeting notch signaling pathway	4
A novel risk model consisting of nine platelet-related gene signatures for predicting prognosis, immune features and drug sensitivity in glioma	4
Decoding mitochondrial stress genes in DCM: towards precision diagnosis and therapy	4
The unidirectional phylogeny of Homo sapiens anchors the origin of modern humans in Eurasia	4
Novel variants require established frameworks: emphasizing the role of ISTH diagnostic and classification guidelines in congenital fibrinogen disorders	4
Screening of ulcerative colitis biomarkers and potential pathways based on weighted gene co-expression network, machine learning and ceRNA hypothesis	4
Identification of crucial genes involved in pathogenesis of regional weakening of the aortic wall	3
An Axin2 mutation and perinatal risk factors contribute to sagittal craniosynostosis: evidence from a Chinese female monochorionic diamniotic twin family	3
Identification of biomarkers, immune infiltration landscape, and treatment targets of ischemia–reperfusion acute kidney injury at an early stage by bioinformatics methods	3
Knockdown of IGF2BP2 overcomes cisplatin-resistance in lung cancer through downregulating Spon2 gene	3
Trimeric complexes of Antp-TBP with TFIIEβ or Exd modulate transcriptional activity	3
Understanding the contemporary high obesity rate from an evolutionary genetic perspective	3
Elevated HMGB1 promotes the malignant progression and contributes to cisplatin resistance of non-small cell lung cancer	3
Mechanistic insights into CDCA gene family-mediated glioblastoma progression: implications for diagnosis, prognosis, and therapeutic targeting	3
RNA binding protein ILF3 increases CEP55 mRNA stability to enhance malignant potential of breast cancer cells and suppress ferroptosis	3
Mutations in the acetolactate synthase (ALS) enzyme affect shattercane (Sorghum bicolor) response to ALS-inhibiting herbicides	3
Acetylation proteomics and metabolomics analyses reveal the involvement of starch synthase undergoing acetylation modification during UV-B stress resistance in Rhododendron Chrysanthum Pall	3
Screening and analysis of programmed cell death related genes and targeted drugs in sepsis	3

Correlation between gut microbiota characteristics and non-small cell lung cancer based on macrogenomics sequencing	2
Protein content and HvNAM alleles in Nordic barley (Hordeum vulgare) during a century of breeding	2
Characterization of key genes and immune cell infiltration associated with endometriosis through integrating bioinformatics and experimental analyses	2
Inhibition of microRNA-660-5p decreases breast cancer progression through direct targeting of TMEM41B	2
A novel molecular subtypes and risk model based on inflammatory response-related lncrnas for bladder cancer	2
A potential immunotherapeutic and prognostic biomarker for multiple tumors including glioma: SHOX2	2
TGF-β1/SMOC2/AKT and ERK axis regulates proliferation, migration, and fibroblast to myofibroblast transformation in lung fibroblast, contributing with the asthma progression	2
A novel mutation of CTC1 leads to telomere shortening in a chinese family with interstitial lung disease	2
Zebrafish nampt-a mutants are viable despite perturbed primitive hematopoiesis	2
Identification and validation of autophagy-related genes in Kawasaki disease	2
Predicting the therapeutic role and potential mechanisms of Indole-3-acetic acid in diminished ovarian reserve based on network pharmacology and molecular docking	2
Investigating the shared genetic structure between rheumatoid arthritis and stroke	2
Correction: Identification and functional characterization of key biomarkers in diffuse large B-cell lymphoma: emphasis on STYX as a prognostic marker and therapeutic target	2
Daidzein and puerarin synergistically suppress gastric cancer proliferation via STAT3/FAK pathway Inhibition	2
m6A-related lncRNA-based immune infiltration characteristic analysis and prognostic model for colonic adenocarcinoma	2
Identification of regulator gene and pathway in myocardial ischemia-reperfusion injury: a bioinformatics and biological validation study	2
Arecoline promotes proliferation and migration of human HepG2 cells through activation of the PI3K/AKT/mTOR pathway	2
Transformation and gene-disruption in the apple-pathogen, Neonectria ditissima	2
Editorial: Celebration of DNA Day	2
Mutation update of SERPING1 related to hereditary angioedema in the Chinese population	2
SOLAMEN syndrome with cardiovascular damage	2
Identification of immune-related mitochondrial metabolic disorder genes in septic shock using bioinformatics and machine learning	2
Genomics in animal breeding from the perspectives of matrices and molecules	2
Development and validation of an RBP gene signature for prognosis prediction in colorectal cancer based on WGCNA	2
miR-31-5p from placental and peripheral blood exosomes is a potential biomarker to diagnose preeclampsia	2
A novel missense mutation (FGG c.1168G > T) in the gamma chain of fibrinogen causing congenital hypodysfibrinogenemia with bleeding phenotype	1
Comprehensive analysis revealed the immunoinflammatory targets of rheumatoid arthritis based on intestinal flora, miRNA, transcription factors, and RNA-binding proteins databases, GSEA and GSVA pathwa	1
Exploration of the molecular mechanism of modified Danggui Liuhuang Decoction in treating central precocious puberty and its effects on hypothalamic-pituitary-gonadal axis hormones	1
ADME gene-driven prognostic model for bladder cancer: a breakthrough in predicting survival and personalized treatment	1
Identifying and predicting the pathogenic effects of a novel variant inducing severe early onset MMA: a bioinformatics approach	1
Comparative pharmacognosy and secondary metabolite analysis of Balanophorae herbs from different sources	1
Corynoxine suppresses lung adenocarcinoma proliferation and metastasis via inhibiting PI3K/AKT pathway and suppressing Cyclooxygenase-2 expression	1
Identification of prognostic biomarker of non-small cell lung cancer based on mitochondrial permeability transition-driven necrosis-related genes and determination of anti-tumor effect of ARL14	1
IFNAR1 gene mutation may contribute to developmental stuttering in the Chinese population	1
Immunomodulatory insights of monoterpene glycosides in endometriosis: immune infiltration and target pathways analysis	1
Integrated analysis of N6-methyladenosine- and 5-methylcytosine-related long non-coding RNAs for predicting prognosis in cervical cancer	1
Deciphering the potential ability of RG108 in cisplatin-induced HEI-OC1 ototoxicity: a research based on RNA-seq and molecular biology experiment	1
Leopard syndrome: the potential cardiac defect underlying skin phenotypes	1
Identification and development of the novel 7-genes diagnostic signature by integrating multi cohorts based on osteoarthritis	1
Somatic frameshift mutation in PIK3CA causes CLOVES syndrome by provoking PI3K/AKT/mTOR pathway	1
Can Omega-3 prevent the accidence of stroke: a mendelian randomization study	1
A novel mutation in the FGG gene causes hypofibrinogenemia in a Chinese family	1
Mir-150-5p distinguishes acute pulmonary embolism, predicts the occurrence of pulmonary arterial hypertension, and regulates ox-LDL-induced endothelial cell injury	1
Multiomics landscape of the autosomal dominant osteopetrosis type II disease-specific induced pluripotent stem cells	1
Correction to: Genetic polymorphism of IDOL gene was associated with the susceptibility of coronary artery disease in Han population in Xinjiang, China	1
Key wound healing genes as diagnostic biomarkers and therapeutic targets in uterine corpus endometrial carcinoma: an integrated in silico and in vitro study	1
The Jan Sjödin faba bean mutant collection: morphological and molecular characterization	1
Complex vascular anomalies and tissue overgrowth of limbs associated with increased skin temperature and peripheral venous dilatation: parks weber syndrome or PROS?	1
Knockdown of AMIGO2 suppresses proliferation and migration through regulating PPAR-γ in bladder cancer	1
Modifiable risk factors that mediate the effect of insomnia on the risk of low back pain: a network mendelian randomization study	1
Identification of mitophagy-related genes in patients with acute myocardial infarction	1
Mir-615-5p inhibits cervical cancer progression by targeting TMIGD2	1
Novel Antennapedia and Ultrabithorax trimeric complexes with TBP and Exd regulate transcription	1
Variations in the TAS2R38 gene among college students in Hubei	1
Integrative bioinformatics analysis of high-throughput sequencing and in vitro functional analysis leads to uncovering key hub genes in esophageal squamous cell carcinoma	1
Exploring MAP3K genes in gastric cancer: biomarkers, tumor microenvironment dynamics, and chemotherapy resistance	1
Identification of four novel hub genes as monitoring biomarkers for colorectal cancer	1
Discovering the key genes and important DNA methylation regions in breast cancer	1
Construction and validation of a cuproptosis-related diagnostic gene signature for atrial fibrillation based on ensemble learning	1