OOIR: Observatory of International Research

Papers

(The TQCC of Immune Network is 8. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-05-01 to 2025-05-01.)

Article	Citations
Phosphatase Ssu72 Is Essential for Homeostatic Balance Between CD4⁺ T Cell Lineages	105
Sphingosylphosphorylcholine Promotes Th9 Cell Differentiation Through Regulation of Smad3, STAT5, and β-Catenin Pathways	99
Dietary Diversity during Early Infancy Increases Microbial Diversity and Prevents Egg Allergy in High-Risk Infants	35
Extracellular Mechanisms of Neutrophils in Immune Cell Crosstalk	28
Beyond Tumor Borders: Intratumoral Microbiome Effects on Tumor Behavior and Therapeutic Responses	27
Amelioration of DSS-Induced Acute Colitis in Mice by Recombinant Monomeric Human Interleukin-22	23
Modeling Incorporating the Severity-Reducing Long-term Immunity: Higher Viral Transmission Paradoxically Reduces Severe COVID-19 During Endemic Transition	21
Current Developments in NK Cell Engagers for Cancer Immunotherapy: Focus on CD16A and NKp46	21
The Role of CD4 T Cell Help in CD8 T Cell Differentiation and Function During Chronic Infection and Cancer	21
IL-1 Receptor Dynamics in Immune Cells: Orchestrating Immune Precision and Balance	19
Impairment of Mitochondrial ATP Synthesis Induces RIPK3-dependent Necroptosis in Lung Epithelial Cells During Lung Injury by Lung Inflammation	17
CAR T Cell Immunotherapy Beyond Haematological Malignancy	16
Optimising IL-2 for Cancer Immunotherapy	15
Increased B Cell Understanding Puts Improved Vaccine Platforms Just Over the Horizon	15
Context-Dependent Regulation of Type17 Immunity by Microbiota at the Intestinal Barrier	15
STING-STAT6 Signaling Pathway Promotes IL-4⁺ and IFN-α⁺ Fibrotic T Cell Activation and Exacerbates Scleroderma in SKG Mice	14
Outstanding Features of COVID-19 Overlapping Primary Immunodeficiency in Children	14
Efficient In Vitro Plasma Cell Differentiation by B Cell Receptor Activation and Cytokine Stimulation	14
Glucocorticoids Impair the 7α-Hydroxycholesterol-Enhanced Innate Immune Response	14
Tissue-Specific Metabolic Reprogramming in Innate Lymphoid Cells and Its Impact on Disease	13
Development of Bispecific Antibody for Cancer Immunotherapy: Focus on T Cell Engaging Antibody	13
Oxidized LDL Accelerates Cartilage Destruction and Inflammatory Chondrocyte Death in Osteoarthritis by Disrupting the TFEB-Regulated Autophagy-Lysosome Pathway	13
Altered Frequency, Activation, and Clinical Relevance of Circulating Innate and Innate-Like Lymphocytes in Patients With Alcoholic Liver Cirrhosis	13
Cigarette Smoke Extract-Treated Mouse Airway Epithelial Cells-Derived Exosomal LncRNA MEG3 Promotes M1 Macrophage Polarization and Pyroptosis in Chronic Obstructive Pulmonary Disease by Upregulating T	12
Increased Inflammatory Responses in Patients With Active Disseminated Non-Tuberculous Mycobacterial Infection and High Anti-Interferon-Gamma Autoantibodies	12

COVID-19 Therapeutics: An Update on Effective Treatments Against Infection With SARS-CoV-2 Variants	12
Characterization of Immune Cells From the Lungs of Patients With Chronic Non-Tuberculous Mycobacteria or Pseudomonas aeruginosa Infection	12
Vaccine Strategy That Enhances the Protective Efficacy of Systemic Immunization by Establishing Lung-Resident Memory CD8 T Cells Against Influenza Infection	12
Transcriptional and Epigenetic Regulation of Context-Dependent Plasticity in T-Helper Lineages	12
Exploring the Potential of Glycolytic Modulation in Myeloid-Derived Suppressor Cells for Immunotherapy and Disease Management	11
Recombinant Human Bone Morphogenetic Protein-2 Priming of Mesenchymal Stem Cells Ameliorate Acute Lung Injury by Inducing Regulatory T Cells	11
Regulatory T Cell Metabolism: A Promising Therapeutic Target for Cancer Treatment?	11
Neutrophil Migration Is Mediated by VLA-6 in the Inflamed Adipose Tissue	11
Change of Dendritic Cell Subsets Involved in Protection Against Listeria monocytogenes Infection in Short-Term-Fasted Mice	10
Shaping Heterogeneity of Naive CD8⁺ T Cell Pools	10
Immunopathology and Immunotherapy of Inflammatory Skin Diseases	10
Mitochondria Activity and CXCR4 Collaboratively Promote the Differentiation of CD11c⁺ B Cells Induced by TLR9 in Lupus	10
SOCS3 Attenuates Dexamethasone-Induced M2 Polarization by Down-Regulation of GILZ via ROS- and p38 MAPK-Dependent Pathways	10
Dexamethasone, but Not Vitamin D or A, Dampens the Inflammatory Neutrophil Response to Protect At-risk COVID-19 Patients	9
NLRP3 Exacerbate NETosis-Associated Neuroinflammation in an LPS-Induced Inflamed Brain	9
Decay-Accelerating Factor Differentially Associates With Complement-Mediated Damage in Synovium After Meniscus Tear as Compared to Anterior Cruciate Ligament Injury	8
Monovalent Anti-CD3 Antibodies Effectively Eliminate the TCR-Positive Fraction of TCR-Deleted Allogeneic CAR-T Cells to Prevent GVHD	8
Obesity Exacerbates Coxsackievirus Infection via Lipid-Induced Mitochondrial Reactive Oxygen Species Generation	8
NADPH Oxidase 4-mediated Alveolar Macrophage Recruitment to Lung Attenuates Neutrophilic Inflammation in Staphylococcus aureus Infection	8
Distinct Transcriptional and Functional Differences of Lung Resident and Monocyte-Derived Alveolar Macrophages During the Recovery Period of Acute Lung Injury	8
Commensal Microbiota and Cancer Immunotherapy: Harnessing Commensal Bacteria for Cancer Therapy	8