OOIR: Observatory of International Research

Papers

(The TQCC of Immune Network is 12. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-05-01 to 2026-05-01.)

Article	Citations
Phosphatase Ssu72 Is Essential for Homeostatic Balance Between CD4⁺ T Cell Lineages	80
Sphingosylphosphorylcholine Promotes Th9 Cell Differentiation Through Regulation of Smad3, STAT5, and β-Catenin Pathways	53
Extracellular Mechanisms of Neutrophils in Immune Cell Crosstalk	44
Advances in IL-2 Family Cytokine-Based Cancer Therapies: Overcoming Challenges Through Molecular Engineering and Delivery Strategies	44
Beyond Tumor Borders: Intratumoral Microbiome Effects on Tumor Behavior and Therapeutic Responses	39
Harnessing the Gut Microbiota to Improve Cancer Immunotherapy: Focus on Lung Cancer	36
The Role of CD4 T Cell Help in CD8 T Cell Differentiation and Function During Chronic Infection and Cancer	33
IL-1 Receptor Dynamics in Immune Cells: Orchestrating Immune Precision and Balance	27
Current Developments in NK Cell Engagers for Cancer Immunotherapy: Focus on CD16A and NKp46	27
Intestinal Dysbiosis Caused by Epithelial Fabp6 Gene Disruption Exacerbates Gut Inflammatory Disease	27
Distinct T Cell Dysregulation Reflects Disease Severity and Progression in Infantile Epileptic Spasms Syndrome and Lennox-Gastaut Syndrome	27
Optimising IL-2 for Cancer Immunotherapy	26
Glucocorticoids Impair the 7α-Hydroxycholesterol-Enhanced Innate Immune Response	25
Strong Immune Privileges of MSC and Other Nes-GFP⁺ Progenitors in Bone Marrow of Transgenic Mice	25
Efficient In Vitro Plasma Cell Differentiation by B Cell Receptor Activation and Cytokine Stimulation	25
Altered Frequency, Activation, and Clinical Relevance of Circulating Innate and Innate-Like Lymphocytes in Patients With Alcoholic Liver Cirrhosis	24
STING-STAT6 Signaling Pathway Promotes IL-4⁺ and IFN-α⁺ Fibrotic T Cell Activation and Exacerbates Scleroderma in SKG Mice	24
Increased Inflammatory Responses in Patients With Active Disseminated Non-Tuberculous Mycobacterial Infection and High Anti-Interferon-Gamma Autoantibodies	23
COVID-19 Therapeutics: An Update on Effective Treatments Against Infection With SARS-CoV-2 Variants	23
From Ex Vivo to In Vivo : Advances in Lentiviral Vector Engineering for CAR-T Therapy	22
Tissue-Specific Metabolic Reprogramming in Innate Lymphoid Cells and Its Impact on Disease	20
Cigarette Smoke Extract-Treated Mouse Airway Epithelial Cells-Derived Exosomal LncRNA MEG3 Promotes M1 Macrophage Polarization and Pyroptosis in Chronic Obstructive Pulmonary Disease by Upregulating T	20
Oxidized LDL Accelerates Cartilage Destruction and Inflammatory Chondrocyte Death in Osteoarthritis by Disrupting the TFEB-Regulated Autophagy-Lysosome Pathway	20
Recombinant Human Bone Morphogenetic Protein-2 Priming of Mesenchymal Stem Cells Ameliorate Acute Lung Injury by Inducing Regulatory T Cells	19
Transcriptional and Epigenetic Regulation of Context-Dependent Plasticity in T-Helper Lineages	19

Neutrophil Migration Is Mediated by VLA-6 in the Inflamed Adipose Tissue	18
Exploring the Potential of Glycolytic Modulation in Myeloid-Derived Suppressor Cells for Immunotherapy and Disease Management	18
SiglecF Expressing Neutrophils Exacerbate Th17-Mediated Autoimmune Neuroinflammation	17
Vaccine Strategy That Enhances the Protective Efficacy of Systemic Immunization by Establishing Lung-Resident Memory CD8 T Cells Against Influenza Infection	17
Regulatory T Cell Metabolism: A Promising Therapeutic Target for Cancer Treatment?	16
Unlocking IL-33: New Insights into Tumor Immunity	15
Enigmatic Roles of Complement Anaphylatoxin Signaling in Health and Disease	14
Shaping Heterogeneity of Naive CD8⁺ T Cell Pools	14
IL7-TBRII, a Dual Cytokine Modulator Targeting IL-7 and TGF-β Pathways, Inhibits Tumor Progression and Metastasis	14
Soluble CCR2-Expressing Mesenchymal Stem Cells Inhibit Osteoarthritis Development and Progression	14
Virus-like Particle Vaccines Containing RSV Fusion Protein Cleavage Mutations Are Immunogenic and Protective in Cotton Rats With a Prime Dose	13
Decay-Accelerating Factor Differentially Associates With Complement-Mediated Damage in Synovium After Meniscus Tear as Compared to Anterior Cruciate Ligament Injury	12
Mitochondria Activity and CXCR4 Collaboratively Promote the Differentiation of CD11c⁺ B Cells Induced by TLR9 in Lupus	12
Monovalent Anti-CD3 Antibodies Effectively Eliminate the TCR-Positive Fraction of TCR-Deleted Allogeneic CAR-T Cells to Prevent GVHD	12
Comparing the Benefits and Drawbacks of Stem Cell Therapy Based on the Cell Origin or Manipulation Process: Addressing Immunogenicity	12
Distinct Transcriptional and Functional Differences of Lung Resident and Monocyte-Derived Alveolar Macrophages During the Recovery Period of Acute Lung Injury	12
Dynamic Interplay Between Tumor Cells and the Immune System	12
NLRP3 Exacerbate NETosis-Associated Neuroinflammation in an LPS-Induced Inflamed Brain	12