OOIR: Observatory of International Research

Papers

(The TQCC of Immune Network is 14. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-06-01 to 2026-06-01.)

Article	Citations
Phosphatase Ssu72 Is Essential for Homeostatic Balance Between CD4⁺ T Cell Lineages	87
Sphingosylphosphorylcholine Promotes Th9 Cell Differentiation Through Regulation of Smad3, STAT5, and β-Catenin Pathways	56
Extracellular Mechanisms of Neutrophils in Immune Cell Crosstalk	49
Advances in IL-2 Family Cytokine-Based Cancer Therapies: Overcoming Challenges Through Molecular Engineering and Delivery Strategies	49
Beyond Tumor Borders: Intratumoral Microbiome Effects on Tumor Behavior and Therapeutic Responses	40
IL-1 Receptor Dynamics in Immune Cells: Orchestrating Immune Precision and Balance	39
Distinct T Cell Dysregulation Reflects Disease Severity and Progression in Infantile Epileptic Spasms Syndrome and Lennox-Gastaut Syndrome	35
Harnessing the Gut Microbiota to Improve Cancer Immunotherapy: Focus on Lung Cancer	29
Current Developments in NK Cell Engagers for Cancer Immunotherapy: Focus on CD16A and NKp46	29
Intestinal Dysbiosis Caused by Epithelial Fabp6 Gene Disruption Exacerbates Gut Inflammatory Disease	28
The Role of CD4 T Cell Help in CD8 T Cell Differentiation and Function During Chronic Infection and Cancer	28
Optimising IL-2 for Cancer Immunotherapy	27
Immunosenescence and Cancer: Cellular Aging Programs That Reshape Antitumor Immunity	27
Glucocorticoids Impair the 7α-Hydroxycholesterol-Enhanced Innate Immune Response	26
Efficient In Vitro Plasma Cell Differentiation by B Cell Receptor Activation and Cytokine Stimulation	26
Strong Immune Privileges of MSC and Other Nes-GFP⁺ Progenitors in Bone Marrow of Transgenic Mice	26
STING-STAT6 Signaling Pathway Promotes IL-4⁺ and IFN-α⁺ Fibrotic T Cell Activation and Exacerbates Scleroderma in SKG Mice	25
COVID-19 Therapeutics: An Update on Effective Treatments Against Infection With SARS-CoV-2 Variants	24
Altered Frequency, Activation, and Clinical Relevance of Circulating Innate and Innate-Like Lymphocytes in Patients With Alcoholic Liver Cirrhosis	24
From Ex Vivo to In Vivo : Advances in Lentiviral Vector Engineering for CAR-T Therapy	23
Increased Inflammatory Responses in Patients With Active Disseminated Non-Tuberculous Mycobacterial Infection and High Anti-Interferon-Gamma Autoantibodies	22
Cigarette Smoke Extract-Treated Mouse Airway Epithelial Cells-Derived Exosomal LncRNA MEG3 Promotes M1 Macrophage Polarization and Pyroptosis in Chronic Obstructive Pulmonary Disease by Upregulating T	21
Oxidized LDL Accelerates Cartilage Destruction and Inflammatory Chondrocyte Death in Osteoarthritis by Disrupting the TFEB-Regulated Autophagy-Lysosome Pathway	21
Tissue-Specific Metabolic Reprogramming in Innate Lymphoid Cells and Its Impact on Disease	21
Transcriptional and Epigenetic Regulation of Context-Dependent Plasticity in T-Helper Lineages	20

Recombinant Human Bone Morphogenetic Protein-2 Priming of Mesenchymal Stem Cells Ameliorate Acute Lung Injury by Inducing Regulatory T Cells	19
Vaccine Strategy That Enhances the Protective Efficacy of Systemic Immunization by Establishing Lung-Resident Memory CD8 T Cells Against Influenza Infection	19
Exploring the Potential of Glycolytic Modulation in Myeloid-Derived Suppressor Cells for Immunotherapy and Disease Management	18
Neutrophil Migration Is Mediated by VLA-6 in the Inflamed Adipose Tissue	17
In Search of Adaptive-Like Features of NK Cells Co-Expressing NKG2C and NKG2A	17
SiglecF Expressing Neutrophils Exacerbate Th17-Mediated Autoimmune Neuroinflammation	16
IL7-TBRII, a Dual Cytokine Modulator Targeting IL-7 and TGF-β Pathways, Inhibits Tumor Progression and Metastasis	15
Unlocking IL-33: New Insights into Tumor Immunity	15
Soluble CCR2-Expressing Mesenchymal Stem Cells Inhibit Osteoarthritis Development and Progression	15
Shaping Heterogeneity of Naive CD8⁺ T Cell Pools	15
Regulatory T Cell Metabolism: A Promising Therapeutic Target for Cancer Treatment?	15
Beyond Perineural Drainage: Revisiting the Olfactory Nerve as an Active Immunological Interface During Neuroinflammation	14
Enigmatic Roles of Complement Anaphylatoxin Signaling in Health and Disease	14
Mitochondria Activity and CXCR4 Collaboratively Promote the Differentiation of CD11c⁺ B Cells Induced by TLR9 in Lupus	14