OOIR: Observatory of International Research

Papers

(The median citation count of Immune Network is 4. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-06-01 to 2026-06-01.)

Article	Citations
Phosphatase Ssu72 Is Essential for Homeostatic Balance Between CD4⁺ T Cell Lineages	87
Sphingosylphosphorylcholine Promotes Th9 Cell Differentiation Through Regulation of Smad3, STAT5, and β-Catenin Pathways	56
Extracellular Mechanisms of Neutrophils in Immune Cell Crosstalk	49
Advances in IL-2 Family Cytokine-Based Cancer Therapies: Overcoming Challenges Through Molecular Engineering and Delivery Strategies	49
Beyond Tumor Borders: Intratumoral Microbiome Effects on Tumor Behavior and Therapeutic Responses	40
IL-1 Receptor Dynamics in Immune Cells: Orchestrating Immune Precision and Balance	39
Distinct T Cell Dysregulation Reflects Disease Severity and Progression in Infantile Epileptic Spasms Syndrome and Lennox-Gastaut Syndrome	35
Harnessing the Gut Microbiota to Improve Cancer Immunotherapy: Focus on Lung Cancer	29
Current Developments in NK Cell Engagers for Cancer Immunotherapy: Focus on CD16A and NKp46	29
The Role of CD4 T Cell Help in CD8 T Cell Differentiation and Function During Chronic Infection and Cancer	28
Intestinal Dysbiosis Caused by Epithelial Fabp6 Gene Disruption Exacerbates Gut Inflammatory Disease	28
Immunosenescence and Cancer: Cellular Aging Programs That Reshape Antitumor Immunity	27
Optimising IL-2 for Cancer Immunotherapy	27
Strong Immune Privileges of MSC and Other Nes-GFP⁺ Progenitors in Bone Marrow of Transgenic Mice	26
Glucocorticoids Impair the 7α-Hydroxycholesterol-Enhanced Innate Immune Response	26
Efficient In Vitro Plasma Cell Differentiation by B Cell Receptor Activation and Cytokine Stimulation	26
STING-STAT6 Signaling Pathway Promotes IL-4⁺ and IFN-α⁺ Fibrotic T Cell Activation and Exacerbates Scleroderma in SKG Mice	25
Altered Frequency, Activation, and Clinical Relevance of Circulating Innate and Innate-Like Lymphocytes in Patients With Alcoholic Liver Cirrhosis	24
COVID-19 Therapeutics: An Update on Effective Treatments Against Infection With SARS-CoV-2 Variants	24
From Ex Vivo to In Vivo : Advances in Lentiviral Vector Engineering for CAR-T Therapy	23
Increased Inflammatory Responses in Patients With Active Disseminated Non-Tuberculous Mycobacterial Infection and High Anti-Interferon-Gamma Autoantibodies	22
Cigarette Smoke Extract-Treated Mouse Airway Epithelial Cells-Derived Exosomal LncRNA MEG3 Promotes M1 Macrophage Polarization and Pyroptosis in Chronic Obstructive Pulmonary Disease by Upregulating T	21
Oxidized LDL Accelerates Cartilage Destruction and Inflammatory Chondrocyte Death in Osteoarthritis by Disrupting the TFEB-Regulated Autophagy-Lysosome Pathway	21
Tissue-Specific Metabolic Reprogramming in Innate Lymphoid Cells and Its Impact on Disease	21
Transcriptional and Epigenetic Regulation of Context-Dependent Plasticity in T-Helper Lineages	20

Recombinant Human Bone Morphogenetic Protein-2 Priming of Mesenchymal Stem Cells Ameliorate Acute Lung Injury by Inducing Regulatory T Cells	19
Vaccine Strategy That Enhances the Protective Efficacy of Systemic Immunization by Establishing Lung-Resident Memory CD8 T Cells Against Influenza Infection	19
Exploring the Potential of Glycolytic Modulation in Myeloid-Derived Suppressor Cells for Immunotherapy and Disease Management	18
Neutrophil Migration Is Mediated by VLA-6 in the Inflamed Adipose Tissue	17
In Search of Adaptive-Like Features of NK Cells Co-Expressing NKG2C and NKG2A	17
SiglecF Expressing Neutrophils Exacerbate Th17-Mediated Autoimmune Neuroinflammation	16
IL7-TBRII, a Dual Cytokine Modulator Targeting IL-7 and TGF-β Pathways, Inhibits Tumor Progression and Metastasis	15
Unlocking IL-33: New Insights into Tumor Immunity	15
Soluble CCR2-Expressing Mesenchymal Stem Cells Inhibit Osteoarthritis Development and Progression	15
Shaping Heterogeneity of Naive CD8⁺ T Cell Pools	15
Regulatory T Cell Metabolism: A Promising Therapeutic Target for Cancer Treatment?	15
Beyond Perineural Drainage: Revisiting the Olfactory Nerve as an Active Immunological Interface During Neuroinflammation	14
Enigmatic Roles of Complement Anaphylatoxin Signaling in Health and Disease	14
Mitochondria Activity and CXCR4 Collaboratively Promote the Differentiation of CD11c⁺ B Cells Induced by TLR9 in Lupus	14
Distinct Transcriptional and Functional Differences of Lung Resident and Monocyte-Derived Alveolar Macrophages During the Recovery Period of Acute Lung Injury	13
NLRP3 Exacerbate NETosis-Associated Neuroinflammation in an LPS-Induced Inflamed Brain	13
Virus-like Particle Vaccines Containing RSV Fusion Protein Cleavage Mutations Are Immunogenic and Protective in Cotton Rats With a Prime Dose	13
Dynamic Interplay Between Tumor Cells and the Immune System	12
Decay-Accelerating Factor Differentially Associates With Complement-Mediated Damage in Synovium After Meniscus Tear as Compared to Anterior Cruciate Ligament Injury	12
Aging Mediates Inflammatory Transformation of Kidney-Resident Macrophages via Thrombospondin-1 Signaling	12
Mitochondrial Regulator CRIF1 Plays a Critical Role in the Development and Homeostasis of Alveolar Macrophages via Maintaining Metabolic Fitness	10
Monovalent Anti-CD3 Antibodies Effectively Eliminate the TCR-Positive Fraction of TCR-Deleted Allogeneic CAR-T Cells to Prevent GVHD	10
Comparing the Benefits and Drawbacks of Stem Cell Therapy Based on the Cell Origin or Manipulation Process: Addressing Immunogenicity	10
NADPH Oxidase 4-mediated Alveolar Macrophage Recruitment to Lung Attenuates Neutrophilic Inflammation in Staphylococcus aureus Infection	10
The Multifaceted Roles of NK Cells in the Context of Murine Cytomegalovirus and Lymphocytic Choriomeningitis Virus Infections	10
Low-Dose Radiotherapy Attenuates Experimental Autoimmune Arthritis by Inducing Apoptosis of Lymphocytes and Fibroblast-Like Synoviocytes	9
Recombinant Human IL-32θ Induces Polarization Into M1-like Macrophage in Human Monocytic Cells	8
Regulatory T Cell Heterogeneity in the Steady State and Tumor	8
Adoptive Cellular Therapies in Pediatric Leukemia Patients After Allogeneic-Hematopoietic Stem Cell Transplants	8
A Moonlighting Protein Secreted by a Nasal Microbiome Fortifies the Innate Host Defense Against Bacterial and Viral Infections	8
Regulation of Ferroptosis in Cancer and Immune Cells	8
Tissue-Resident ILC2s Across Organs: Heterogeneity, Niche Crosstalk, and Shared Regulatory Circuits	7
Comprehensive Transcriptomic Analysis for Thymic Epithelial Cells of Aged Mice and Humans	7
Tumor Cells as Architects of Immune Refractoriness: Dismantling Intrinsic Programs of Tumor Cells for Clinical Translation	7
Complement Anaphylatoxin C5a-Induced Mouse Lymphatic Functions Modulate Interactions Between Endothelial Cells and T Lymphocytes	7
Metabolic Challenges in Anticancer CD8 T Cell Functions	7
The Impact of Pulmonary Disorders on Neurological Health (Lung-Brain Axis)	7
The Role of Inflammasome-Associated Innate Immune Receptors in Cancer	7
Roles of Virtual Memory T Cells in Diseases	6
T Cell Microvilli: Finger-Shaped External Structures Linked to the Fate of T Cells	6
Bone Marrow Progenitors and IL-2 Signaling Contribute to the Strain Differences of Kidney Innate Lymphoid Cells	6
Diverse Functions of Macrophages in Obesity and Metabolic Dysfunction-Associated Steatotic Liver Disease: Bridging Inflammation and Metabolism	6
Cytokines, Vascular Endothelial Growth Factors, and PlGF in Autoimmunity: Insights From Rheumatoid Arthritis to Multiple Sclerosis	6
Modulation of Immune Responses by Metabolic Reprogramming: The Key Role of Immunometabolism	6
Bifidobacterium longum RAPO Attenuates Dermal and Pulmonary Fibrosis in a Mouse Model of Systemic Sclerosis through Macrophage Modulation and Growth of Short-Chain Fatty Acid Producers	6
Cytokines and Immune Disorders: Illuminating Cytokines as Hubs Within the Immune Network	5
Interleukin-18 Binding Protein (IL-18BP): A Long Journey From Discovery to Clinical Application	5
IL-17 and IL-21: Their Immunobiology and Therapeutic Potentials	5
COVID-19 Vaccination Alters NK Cell Dynamics and Transiently Reduces HBsAg Titers Among Patients With Chronic Hepatitis B	5
T Cell Resistance: On the Mechanisms of T Cell Non-activation	5

Cytokine Storm Related to CD4⁺ T Cells in Influenza Virus-Associated Acute Necrotizing Encephalopathy	5
Influenza Virus-Derived CD8 T Cell Epitopes: Implications for the Development of Universal Influenza Vaccines	4
Cytokine Engineering in CAR-T Cell Therapy: Next-Generation Strategies	4