OOIR: Observatory of International Research

Papers

(The median citation count of Immune Network is 4. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-11-01 to 2024-11-01.)

Article	Citations
Targeted Immunotherapy for Autoimmune Disease	75
Immune Checkpoint Inhibitors in 10 Years: Contribution of Basic Research and Clinical Application in Cancer Immunotherapy	75
Adenovirus Vectors: Excellent Tools for Vaccine Development	72
SARS-CoV-2 Delta (B.1.617.2) Variant: A Unique T478K Mutation in Receptor Binding Motif (RBM) of Spike Gene	55
Gut-Brain Connection: Microbiome, Gut Barrier, and Environmental Sensors	51
SARS-CoV-2 Infection of Airway Epithelial Cells	49
SARS-CoV-2 Omicron Mutation Is Faster than the Chase: Multiple Mutations on Spike/ACE2 Interaction Residues	48
Current Status of COVID-19 Vaccine Development: Focusing on Antigen Design and Clinical Trials on Later Stages	29
Toll-like Receptor 2 in Autoimmune Inflammation	29
Nucleocapsid and Spike Proteins of SARS-CoV-2 Drive Neutrophil Extracellular Trap Formation	24
The Role of T Cells in Obesity-Associated Inflammation and Metabolic Disease	24
Ongoing Clinical Trials of Vaccines to Fight against COVID-19 Pandemic	23
Immunopathology and Immunotherapy of Inflammatory Skin Diseases	21
Hepatitis B virus X Protein Promotes Liver Cancer Progression through Autophagy Induction in Response to TLR4 Stimulation	21
The Role of Upper Airway Microbiome in the Development of Adult Asthma	20
Development of Bispecific Antibody for Cancer Immunotherapy: Focus on T Cell Engaging Antibody	19
Targeting the Epithelium-Derived Innate Cytokines: From Bench to Bedside	18
CD11b Deficiency Exacerbates Methicillin-ResistantStaphylococcus aureus-Induced Sepsis by Upregulating Inflammatory Responses of Macrophages	16
Transmission Characteristics of SARS-CoV-2 That Hinder Effective Control	15
Experimental Animal Models of Coronavirus Infections: Strengths and Limitations	15
Mechanisms Underlying the Role of Myeloid-Derived Suppressor Cells in Clinical Diseases: Good or Bad	15
Recent Advances in Allergen-Specific Immunotherapy in Humans: A Systematic Review	14
Commensal Microbiota and Cancer Immunotherapy: Harnessing Commensal Bacteria for Cancer Therapy	13
CAR T Cell Immunotherapy Beyond Haematological Malignancy	13
Advancements of Common Gamma-Chain Family Cytokines in Cancer Immunotherapy	13

Comparison of Antibody and T Cell Responses Induced by Single Doses of ChAdOx1 nCoV-19 and BNT162b2 Vaccines	13
Molecular Mechanisms of T Helper Cell Differentiation and Functional Specialization	13
Lessons From the Success and Failure of Targeted Drugs for Rheumatoid Arthritis: Perspectives for Effective Basic and Translational Research	12
SARS-CoV-2-Specific T Cell Responses in Patients with COVID-19 and Unexposed Individuals	12
Single Cell Transcriptomic Re-analysis of Immune Cells in Bronchoalveolar Lavage Fluids Reveals the Correlation of B Cell Characteristics and Disease Severity of Patients with SARS-CoV-2 Infection	12
Omicron Subvariants, Including BA.4 and BA.5, Substantially Preserve T Cell Epitopes of Ancestral SARS-CoV-2	12
NLRP3 Exacerbate NETosis-Associated Neuroinflammation in an LPS-Induced Inflamed Brain	11
Dietary Diversity during Early Infancy Increases Microbial Diversity and Prevents Egg Allergy in High-Risk Infants	11
Context-Dependent Regulation of Type17 Immunity by Microbiota at the Intestinal Barrier	11
Mitochondrial Transplantation Ameliorates the Development and Progression of Osteoarthritis	11
Recent Advances in Cell Therapeutics for Systemic Autoimmune Diseases	11
Gut Microbial Metabolites on Host Immune Responses in Health and Disease	11
Mitofusin-2 Promotes the Epithelial-Mesenchymal Transition-Induced Cervical Cancer Progression	10
Exosomal Communication Between the Tumor Microenvironment and Innate Immunity and Its Therapeutic Application	10
Human CD8⁺ T-Cell Populations That Express Natural Killer Receptors	10
MiR-182-5p Mediated by Exosomes Derived From Bone Marrow Mesenchymal Stem Cell Attenuates Inflammatory Responses by Targeting TLR4 in a Mouse Model of Myocardial Infraction	10
Understanding the Host Innate Immune Responses against SARS-CoV-2 Infection and COVID-19 Pathogenesis	9
Inhibition of Chitinase-3-like-1 by K284-6111 Reduces Atopic Skin Inflammation via Repressing Lactoferrin	9
Enriching CCL3 in the Tumor Microenvironment Facilitates T cell Responses and Improves the Efficacy of Anti-PD-1 Therapy	9
Correlation between Reactogenicity and Immunogenicity after the ChAdOx1 nCoV-19 and BNT162b2 mRNA Vaccination	9
As a Modulator, Multitasking Roles of SIRT1 in Respiratory Diseases	9
COVID-19 Antiviral and Treatment Candidates: Current Status	8
Expanded IL-22⁺ Group 3 Innate Lymphoid Cells and Role of Oxidized LDL-C in the Pathogenesis of Axial Spondyloarthritis with Dyslipidaemia	8
NLRC4 Inflammasome-Mediated Regulation of Eosinophilic Functions	8
Transcriptional and Epigenetic Regulation of Context-Dependent Plasticity in T-Helper Lineages	8
IL-34 Aggravates Steroid-Induced Osteonecrosis of the Femoral Head via Promoting Osteoclast Differentiation	8
Inflammasome-Dependent Peroxiredoxin 2 Secretion Induces the Classical Complement Pathway Activation	7
Tumor-Infiltrating Neutrophils and Non-Classical Monocytes May Be Potential Therapeutic Targets for HER2^negative Gastric Cancer	7
SOCS3 Attenuates Dexamethasone-Induced M2 Polarization by Down-Regulation of GILZ via ROS- and p38 MAPK-Dependent Pathways	7
Vitamin D Attenuates Pain and Cartilage Destruction in OA Animals via Enhancing Autophagic Flux and Attenuating Inflammatory Cell Death	7
Dexamethasone, but Not Vitamin D or A, Dampens the Inflammatory Neutrophil Response to Protect At-risk COVID-19 Patients	7
Mesenchymal Stem Cells Attenuate Asthmatic Inflammation and Airway Remodeling by Modulating Macrophages/Monocytes in the IL-13-Overexpressing Mouse Model	7
Immunologic Basis of Type 2 Biologics for Severe Asthma	7
A “Prime and Deploy” Strategy for Universal Influenza Vaccine Targeting Nucleoprotein Induces Lung-Resident Memory CD8 T cells	7
RNA Metabolism in T Lymphocytes	7
Shaping Heterogeneity of Naive CD8⁺ T Cell Pools	7
SARS-CoV-2 Infection Induces HMGB1 Secretion Through Post-Translational Modification and PANoptosis	6
SARS-CoV-2 Antibody Neutralization Assay Platforms Based on Epitopes Sources: Live Virus, Pseudovirus, and Recombinant S Glycoprotein RBD	6
The Function of Memory CD8+ T Cells in Immunotherapy for Human Diseases	6
Intranasal Vaccination with Outer-Membrane Protein ofOrientia tsutsugamushiinduces Protective Immunity Against Scrub Typhus	6
Increase of Vδ2⁺ T Cells That Robustly Produce IL-17A in Advanced Abdominal Aortic Aneurysm Tissues	6
IL-17A and Th17 Cells Contribute to Endometrial Cell Survival by Inhibiting Apoptosis and NK Cell Mediated Cytotoxicity of Endometrial Cells via ERK1/2 Pathway	6
Interactions between NCR⁺ILC3s and the Microbiome in the Airways Shape Asthma Severity	6
Engineering Cell Therapies for Autoimmune Diseases: From Preclinical to Clinical Proof of Concept	6
Protective Efficacy and Immunogenicity of Rv0351/Rv3628 Subunit Vaccine Formulated in Different Adjuvants Against Mycobacterium tuberculosis Infection	6
Amelioration of DSS-Induced Acute Colitis in Mice by Recombinant Monomeric Human Interleukin-22	6
IFN-γ: A Crucial Player in the Fight Against HBV Infection?	5
Roles of Virtual Memory T Cells in Diseases	5
Modulation of Pro-inflammatory and Anti-inflammatory Cytokines in the Fat by an Aloe Gel-based Formula, QDMC, Is Correlated with Altered Gut Microbiota	5
Integration and Reanalysis of Four RNA-Seq Datasets Including BALF, Nasopharyngeal Swabs, Lung Biopsy, and Mouse Models Reveals Common Immune Features of COVID-19	5

Induction of Anti-Aquaporin 5 Autoantibody Production by Immunization with a Peptide Derived from the Aquaporin of Prevotella melaninogenica Leads to Reduced Salivary Flow in Mice	5
Impairment of Mitochondrial ATP Synthesis Induces RIPK3-dependent Necroptosis in Lung Epithelial Cells During Lung Injury by Lung Inflammation	5
TNF in Human Tuberculosis: A Double-Edged Sword	5
Monocytes Contribute to IFN-β Production via the MyD88-Dependent Pathway and Cytotoxic T-Cell Responses against Mucosal Respiratory Syncytial Virus Infection	5
Induction of Peptide-specific CTL Activity and Inhibition of Tumor Growth Following Immunization with Nanoparticles Coated with Tumor Peptide-MHC-I Complexes	5
Indoleamine 2,3-Dioxygenase in Hematopoietic Stem Cell-Derived Cells Suppresses Rhinovirus-Induced Neutrophilic Airway Inflammation by Regulating Th1- and Th17-Type Responses	5
Extracellular Mechanisms of Neutrophils in Immune Cell Crosstalk	5
Sputum Processing Method for Lateral Flow Immunochromatographic Assays to Detect Coronaviruses	5
Low Neutralizing Activities to the Omicron Subvariants BN.1 and XBB.1.5 of Sera From the Individuals Vaccinated With a BA.4/5-Containing Bivalent mRNA Vaccine	5
Induction of Unique STAT Heterodimers by IL-21 Provokes IL-1RI Expression on CD8⁺T Cells, Resulting in Enhanced IL-1β Dependent Effector Function	4
A Potential New Mouse Model of Axial Spondyloarthritis Involving the Complement System	4
Comparison of Waning Immunity Between Booster Vaccination and 2-Dose Vaccination With BNT162b2	4
Pathophysiological Role of TLR4 in Chronic Relapsing Itch Induced by Subcutaneous Capsaicin Injection in Neonatal Rats	4
Microbial Components and Effector Molecules in T Helper Cell Differentiation and Function	4
Evaluation of Immunoproteasome-Specific Proteolytic Activity Using Fluorogenic Peptide Substrates	4
The Immunosuppressive Potential of Cholesterol Sulfate Through T Cell Microvilli Disruption	4
Distinct Transcriptional and Functional Differences of Lung Resident and Monocyte-Derived Alveolar Macrophages During the Recovery Period of Acute Lung Injury	4
T Cell Microvilli: Finger-Shaped External Structures Linked to the Fate of T Cells	4