OOIR: Observatory of International Research

Papers

(The median citation count of Immune Network is 3. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-05-01 to 2025-05-01.)

Article	Citations
Phosphatase Ssu72 Is Essential for Homeostatic Balance Between CD4⁺ T Cell Lineages	105
Sphingosylphosphorylcholine Promotes Th9 Cell Differentiation Through Regulation of Smad3, STAT5, and β-Catenin Pathways	99
Dietary Diversity during Early Infancy Increases Microbial Diversity and Prevents Egg Allergy in High-Risk Infants	35
Extracellular Mechanisms of Neutrophils in Immune Cell Crosstalk	28
Beyond Tumor Borders: Intratumoral Microbiome Effects on Tumor Behavior and Therapeutic Responses	27
Amelioration of DSS-Induced Acute Colitis in Mice by Recombinant Monomeric Human Interleukin-22	23
The Role of CD4 T Cell Help in CD8 T Cell Differentiation and Function During Chronic Infection and Cancer	21
Modeling Incorporating the Severity-Reducing Long-term Immunity: Higher Viral Transmission Paradoxically Reduces Severe COVID-19 During Endemic Transition	21
Current Developments in NK Cell Engagers for Cancer Immunotherapy: Focus on CD16A and NKp46	21
IL-1 Receptor Dynamics in Immune Cells: Orchestrating Immune Precision and Balance	19
Impairment of Mitochondrial ATP Synthesis Induces RIPK3-dependent Necroptosis in Lung Epithelial Cells During Lung Injury by Lung Inflammation	17
CAR T Cell Immunotherapy Beyond Haematological Malignancy	16
Context-Dependent Regulation of Type17 Immunity by Microbiota at the Intestinal Barrier	15
Optimising IL-2 for Cancer Immunotherapy	15
Increased B Cell Understanding Puts Improved Vaccine Platforms Just Over the Horizon	15
Glucocorticoids Impair the 7α-Hydroxycholesterol-Enhanced Innate Immune Response	14
STING-STAT6 Signaling Pathway Promotes IL-4⁺ and IFN-α⁺ Fibrotic T Cell Activation and Exacerbates Scleroderma in SKG Mice	14
Outstanding Features of COVID-19 Overlapping Primary Immunodeficiency in Children	14
Efficient In Vitro Plasma Cell Differentiation by B Cell Receptor Activation and Cytokine Stimulation	14
Oxidized LDL Accelerates Cartilage Destruction and Inflammatory Chondrocyte Death in Osteoarthritis by Disrupting the TFEB-Regulated Autophagy-Lysosome Pathway	13
Altered Frequency, Activation, and Clinical Relevance of Circulating Innate and Innate-Like Lymphocytes in Patients With Alcoholic Liver Cirrhosis	13
Tissue-Specific Metabolic Reprogramming in Innate Lymphoid Cells and Its Impact on Disease	13
Development of Bispecific Antibody for Cancer Immunotherapy: Focus on T Cell Engaging Antibody	13
Vaccine Strategy That Enhances the Protective Efficacy of Systemic Immunization by Establishing Lung-Resident Memory CD8 T Cells Against Influenza Infection	12
Transcriptional and Epigenetic Regulation of Context-Dependent Plasticity in T-Helper Lineages	12

Cigarette Smoke Extract-Treated Mouse Airway Epithelial Cells-Derived Exosomal LncRNA MEG3 Promotes M1 Macrophage Polarization and Pyroptosis in Chronic Obstructive Pulmonary Disease by Upregulating T	12
Increased Inflammatory Responses in Patients With Active Disseminated Non-Tuberculous Mycobacterial Infection and High Anti-Interferon-Gamma Autoantibodies	12
COVID-19 Therapeutics: An Update on Effective Treatments Against Infection With SARS-CoV-2 Variants	12
Characterization of Immune Cells From the Lungs of Patients With Chronic Non-Tuberculous Mycobacteria or Pseudomonas aeruginosa Infection	12
Neutrophil Migration Is Mediated by VLA-6 in the Inflamed Adipose Tissue	11
Exploring the Potential of Glycolytic Modulation in Myeloid-Derived Suppressor Cells for Immunotherapy and Disease Management	11
Recombinant Human Bone Morphogenetic Protein-2 Priming of Mesenchymal Stem Cells Ameliorate Acute Lung Injury by Inducing Regulatory T Cells	11
Regulatory T Cell Metabolism: A Promising Therapeutic Target for Cancer Treatment?	11
Mitochondria Activity and CXCR4 Collaboratively Promote the Differentiation of CD11c⁺ B Cells Induced by TLR9 in Lupus	10
SOCS3 Attenuates Dexamethasone-Induced M2 Polarization by Down-Regulation of GILZ via ROS- and p38 MAPK-Dependent Pathways	10
Change of Dendritic Cell Subsets Involved in Protection Against Listeria monocytogenes Infection in Short-Term-Fasted Mice	10
Shaping Heterogeneity of Naive CD8⁺ T Cell Pools	10
Immunopathology and Immunotherapy of Inflammatory Skin Diseases	10
Dexamethasone, but Not Vitamin D or A, Dampens the Inflammatory Neutrophil Response to Protect At-risk COVID-19 Patients	9
NLRP3 Exacerbate NETosis-Associated Neuroinflammation in an LPS-Induced Inflamed Brain	9
Distinct Transcriptional and Functional Differences of Lung Resident and Monocyte-Derived Alveolar Macrophages During the Recovery Period of Acute Lung Injury	8
Commensal Microbiota and Cancer Immunotherapy: Harnessing Commensal Bacteria for Cancer Therapy	8
Decay-Accelerating Factor Differentially Associates With Complement-Mediated Damage in Synovium After Meniscus Tear as Compared to Anterior Cruciate Ligament Injury	8
Monovalent Anti-CD3 Antibodies Effectively Eliminate the TCR-Positive Fraction of TCR-Deleted Allogeneic CAR-T Cells to Prevent GVHD	8
Obesity Exacerbates Coxsackievirus Infection via Lipid-Induced Mitochondrial Reactive Oxygen Species Generation	8
NADPH Oxidase 4-mediated Alveolar Macrophage Recruitment to Lung Attenuates Neutrophilic Inflammation in Staphylococcus aureus Infection	8
Mitochondrial Regulator CRIF1 Plays a Critical Role in the Development and Homeostasis of Alveolar Macrophages via Maintaining Metabolic Fitness	7
Low-Dose Radiotherapy Attenuates Experimental Autoimmune Arthritis by Inducing Apoptosis of Lymphocytes and Fibroblast-Like Synoviocytes	7
Comparing the Benefits and Drawbacks of Stem Cell Therapy Based on the Cell Origin or Manipulation Process: Addressing Immunogenicity	7
Trypanosoma cruzi Dysregulates piRNAs Computationally Predicted to Target IL-6 Signaling Molecules During Early Infection of Primary Human Cardiac Fibroblasts	7
Regulation of Ferroptosis in Cancer and Immune Cells	7
The Multifaceted Roles of NK Cells in the Context of Murine Cytomegalovirus and Lymphocytic Choriomeningitis Virus Infections	7
The Impact of Pulmonary Disorders on Neurological Health (Lung-Brain Axis)	6
Recombinant Human IL-32θ Induces Polarization Into M1-like Macrophage in Human Monocytic Cells	6
Metabolic Challenges in Anticancer CD8 T Cell Functions	6
The Role of Inflammasome-Associated Innate Immune Receptors in Cancer	6
Omicron Subvariants, Including BA.4 and BA.5, Substantially Preserve T Cell Epitopes of Ancestral SARS-CoV-2	6
A Moonlighting Protein Secreted by a Nasal Microbiome Fortifies the Innate Host Defense Against Bacterial and Viral Infections	6
Mitochondrial Transplantation Ameliorates the Development and Progression of Osteoarthritis	5
Comprehensive Transcriptomic Analysis for Thymic Epithelial Cells of Aged Mice and Humans	5
Roles of Virtual Memory T Cells in Diseases	5
Diverse Functions of Macrophages in Obesity and Metabolic Dysfunction-Associated Steatotic Liver Disease: Bridging Inflammation and Metabolism	5
Cytokines, Vascular Endothelial Growth Factors, and PlGF in Autoimmunity: Insights From Rheumatoid Arthritis to Multiple Sclerosis	5
Bone Marrow Progenitors and IL-2 Signaling Contribute to the Strain Differences of Kidney Innate Lymphoid Cells	4
Interleukin-18 Binding Protein (IL-18BP): A Long Journey From Discovery to Clinical Application	4
T Cell Microvilli: Finger-Shaped External Structures Linked to the Fate of T Cells	4
Modulation of Immune Responses by Metabolic Reprogramming: The Key Role of Immunometabolism	4
Cytokine Inductions and Intracellular Signal Profiles by Stimulation of dsRNA and SEB in the Macrophages and Epithelial Cells	4
Cytokine Storm Related to CD4⁺ T Cells in Influenza Virus-Associated Acute Necrotizing Encephalopathy	4
Evaluation of Immunoproteasome-Specific Proteolytic Activity Using Fluorogenic Peptide Substrates	4
Bifidobacterium longum RAPO Attenuates Dermal and Pulmonary Fibrosis in a Mouse Model of Systemic Sclerosis through Macrophage Modulation and Growth of Short-Chain Fatty Acid Producers	4
Synovial Fluid as a Crucial Component of the Joint Microenvironment in Rheumatoid Arthritis	3
Advancements of Common Gamma-Chain Family Cytokines in Cancer Immunotherapy	3
IL-17 and IL-21: Their Immunobiology and Therapeutic Potentials	3
Application of Antimicrobial Peptide LL-37 as an Adjuvant for Middle East Respiratory Syndrome-Coronavirus Antigen Induces an Efficient Protective Immune Response Against Viral Infection After Intrana	3

Exosomes in Action: Unraveling Their Role in Autoimmune Diseases and Exploring Potential Therapeutic Applications	3
Role of the Aryl Hydrocarbon Receptor in the Self-Renewal, Differentiation, and Immunomodulation of Adult Stem Cells	3
Engineering Cell Therapies for Autoimmune Diseases: From Preclinical to Clinical Proof of Concept	3
Cytokines and Immune Disorders: Illuminating Cytokines as Hubs Within the Immune Network	3
Influenza Virus-Derived CD8 T Cell Epitopes: Implications for the Development of Universal Influenza Vaccines	3
Immune Cells Are Differentially Affected by SARS-CoV-2 Viral Loads in K18-hACE2 Mice	3
Targeted Immunotherapy for Autoimmune Disease	3
COVID-19 Vaccination Alters NK Cell Dynamics and Transiently Reduces HBsAg Titers Among Patients With Chronic Hepatitis B	3
T Cell Resistance: On the Mechanisms of T Cell Non-activation	3
Recent Advances in Allergen-Specific Immunotherapy in Humans: A Systematic Review	3
Tobacco Smoking Could Accentuate Epithelial-Mesenchymal Transition and Th2-Type Response in Patients With Chronic Rhinosinusitis With Nasal Polyps	3