Recent Patents on Anti-Cancer Drug Discovery

Papers
(The TQCC of Recent Patents on Anti-Cancer Drug Discovery is 6. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-05-01 to 2026-05-01.)
ArticleCitations
Acknowledgement to Contributors56
Acknowledgement to Reviewers52
Current Prospects for Adrenocortical Carcinoma Pharmacotherapy34
ZNF146-Mediated HMGB1-NF-κB Signaling Activation as a Therapeutic Target and Prognostic Biomarker in Osteosarcoma31
Comprehensive Genomic Analysis of Puerarin in Inhibiting Bladder Urothelial Carcinoma Cell Proliferation and Migration20
Advanced Strategies of CAR-T Cell Therapy in Solid Tumors and Hematological Malignancies20
Research Progress on the Anticancer Activity of Plant Polysaccharides18
L-Selenomethylselenocysteine Exerts Inhibitory Effects on the Progression of Esophageal Cancer by Targeting the PI3K/AKT Signaling Pathway18
Bioinformatic Analysis and Experimental Validation of HMGA2-AS1 as a Prognostic Biomarker Associated with Immune Infiltration in Gastric Cancer17
Radiotherapy Enhancing and Radioprotective Properties of Berberine: A Systematic Review17
Protective Assessment of Novel (BNC Formulation) against Brain Tumor17
Patent Selections17
Statin Use and Hepatocellular Carcinoma Risk: A Comprehensive Meta-Analysis and Systematic Review15
Nanomaterials for Diagnosis and Treatment of Lung Cancer: A Review of Recent Patents15
The Present State and Potential Applications of Artificial Intelligence in Cancer Diagnosis and Treatment14
Alpha-solanine Anti-tumor Effects in Non-small Cell Lung Cancer Through Regulating the Energy Metabolism Pathway14
Oral Metronomic Chemotherapy in Nasopharyngeal Carcinoma with Radiotherapy Interruptions: A Lesson Learned from the Lockdown Due to COVID-1914
Network Pharmacology-based Prediction and Verification of Shikonin for Treating Colorectal Cancer14
The Prognostic Role of Interferon Gamma-inducible Protein 30 in Clear Cell Renal Cell Carcinoma with Immune Infiltrates14
The Application of Nanotechnology in Immunotherapy based Combinations for Cancer Treatment14
Prognostic Value of Fatty Acid Metabolism-related Genes in Patients with Bladder Cancer14
Vitexin’s Role in Colon Cancer Apoptosis: AMPK/mTOR Pathway Modulation Explored Through Experimental and Computational Approaches13
Bioinformatics Analysis of Key Genes Associated with Resistance to the Combination of Bevacizumab and Pemetrexed Chemotherapy in Non-small Cell Lung Cancer13
Regulating Lipid Metabolism via Mitochondrial Dynamics in Tongue Squamous Cell Carcinoma Cancer Stem Cells13
Acknowledgement To Reviewers13
USP31 Activates the Wnt/β-catenin Signaling Pathway and Promotes Gastric Cancer Cell Proliferation, Invasion and Migration13
Bourgeoning Cancer Targets12
The Causal Effects of Cholelithiasis on Acute Pancreatitis and Pancreatic Cancer: A Large Sample Size Mendelian Randomization Analysis12
Survival Benefits of Ganoderma Lucidum in Early-stage Triple-negative Breast Cancer: A Real World Study12
Patent Selections12
Integrated Single-cell and Bulk RNA Sequencing Analysis Cross Talk between Ferroptosis-related Genes and Prognosis in Oral Cavity Squamous Cell Carcinoma11
Mechanisms of Anti-PD Therapy Resistance in Digestive System Neoplasms11
Prospective Challenges for Patenting and Clinical Trials of Anticancer Compounds from Natural Products: Coherent Review10
Predictive Modelling of Overall Survival in Adult Patients with Primary Diffuse Large B-cell Lymphoma of the Breast Using the Surveillance, Epidemiology, and End Results (SEER) Database10
Meet the Editorial Board Member10
Mir-338-3p Increases the Sensitivity to Oxaliplatin via Reversing Epithelialmesenchymal Transition in Hepatocellular Carcinoma Cells10
lncRNA H22954 Inhibits Angiogenesis in Acute Myeloid Leukemia through a PDGFA-dependent Mechanism10
Patent Selections10
Screening of Candidate Inflammatory Markers of Epithelial Cells in Hepatocellular Carcinoma based on Integration Analysis of TCGA/ICGC Databases and Single-cell Sequencing10
Intracholecystic Papillary-tubular Neoplasm (ICPN) of the Gallbladder: A Case Report Focusing on an Unexpected Pathological Finding10
The m 6 A Reader IGF2BP2 Promotes Oral Squamous Cell Carcinoma Progression by Maintaining UCA1 Stability9
Puerarin: An Anticancer and Anti-Inflammatory Agent9
Application of Nano Drug Delivery System (NDDS) in Cancer Therapy: A Perspective9
Construction and Identification of a Human Colorectal Adenoma Epithelial Cell Line by SV40 Large T-antigen Transfection8
Ubiquitination-related Gene UBTD1 Mediates Poor Prognosis of Colorectal Cancer and Affects Colorectal Cancer Cell Proliferation and Ferroptosis8
Targeting the Key Signaling Pathways in Breast Cancer: From Molecular Mechanism to Therapeutic Interventions8
SSPH I, A Novel Anti-cancer Saponin, Inhibits EMT and Invasion and Migration of NSCLC by Suppressing MAPK/ERK1/2 and PI3K/AKT/ mTOR Signaling Pathways8
Acknowledgement to Reviewers8
Natural STAT3 Inhibitors for Cancer Treatment: A Comprehensive Literature Review8
Circular RNA NF1-419 Inhibits Proliferation and Induces Apoptosis by Regulating Lipid Metabolism in Astroglioma Cells8
Fatty Acid Synthase (FASN): A Patent Review Since 2016-Present7
Targeted Regulation of Osteoblasts and Osteoclasts in Osteosarcoma Patients by CSF3R Receptor Inhibition of Osteolysis Caused by Tumor Inflammation Based on Transcriptional Spectrum Analysis and Drug 7
Prognostic and Therapeutic Values of Autophagy-related Genes in Triple-negative Breast Cancer7
The Synergistic Effect of Ruthenium Complex Δ-Ru1 and Doxorubicin in a Mouse Breast Cancer Model7
Preface7
Aucubin Inhibits Liver Cancer via HMGB1-mediated Inactivation of the PI3K/AKT/mTOR Signaling Pathway7
The FJQR Has Synergistic Effect with Fluoropyrimidine in the Maintenance Treatment for HER-2 Negative Gastric Cancer7
Exploring the Anticancer Potentials of Polyphenols: A Comprehensive Review of Patents in the Last Five Years6
Investigating the Therapeutic Potential and Molecular Mechanisms ofDaphnetin: A Comprehensive Review6
A Synergistic Combination of Oleanolic Acid and Apatinib to Enhance Antitumor Effect on Liver Cancer Cells and Protect against Hepatic Injury6
Adverse Effects of Gefitinib on Skin and Colon in a Lung Cancer Mouse Model6
UBE2L3 Suppresses Oxidative Stress-regulated Necroptosis to Accelerate Osteosarcoma Progression6
Advances in the Treatment of Chronic Myeloid Leukemia6
Patent Selections6
pH-responsive Sulfated Hyaluronic Acid Nanoparticles Targeting Tumor Cells and CAFs for the Treatment of Breast Cancer6
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