Recent Patents on Anti-Cancer Drug Discovery

Papers
(The TQCC of Recent Patents on Anti-Cancer Drug Discovery is 6. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-12-01 to 2025-12-01.)
ArticleCitations
Acknowledgement to Contributors47
Acknowledgement to Reviewers35
Current Prospects for Adrenocortical Carcinoma Pharmacotherapy28
L-Selenomethylselenocysteine Exerts Inhibitory Effects on the Progressionof Esophageal Cancer by Targeting the PI3K/AKT Signaling Pathway24
Research Progress on the Anticancer Activity of Plant Polysaccharides22
Advanced Strategies of CAR-T Cell Therapy in Solid Tumors and Hematological Malignancies19
Patent Selections18
Comprehensive Genomic Analysis of Puerarin in Inhibiting Bladder Urothelial Carcinoma Cell Proliferation and Migration18
Statin Use and Hepatocellular Carcinoma Risk: A Comprehensive Meta-Analysis and Systematic Review16
Protective Assessment of Novel (BNC Formulation) against Brain Tumor16
Bioinformatic Analysis and Experimental Validation of HMGA2-AS1 as a Prognostic Biomarker Associated with Immune Infiltration in Gastric Cancer16
The Prognostic Role of Interferon Gamma-inducible Protein 30 in ClearCell Renal Cell Carcinoma with Immune Infiltrates15
Oral Metronomic Chemotherapy in Nasopharyngeal Carcinoma withRadiotherapy Interruptions: A Lesson Learned from the Lockdown Due toCOVID-1915
Radiotherapy Enhancing and Radioprotective Properties of Berberine: A Systematic Review15
The Present State and Potential Applications of Artificial Intelligence in Cancer Diagnosis and Treatment15
Nanomaterials for Diagnosis and Treatment of Lung Cancer: A Review of Recent Patents15
Alpha-solanine Anti-tumor Effects in Non-small Cell Lung Cancer Through Regulating the Energy Metabolism Pathway14
The Application of Nanotechnology in Immunotherapy based Combinations for Cancer Treatment14
Acknowledgement To Reviewers13
Prognostic Value of Fatty Acid Metabolism-related Genes in Patients with Bladder Cancer13
Network Pharmacology-based Prediction and Verification of Shikonin for Treating Colorectal Cancer13
Regulating Lipid Metabolism via Mitochondrial Dynamics in Tongue Squamous Cell Carcinoma Cancer Stem Cells13
Vitexin’s Role in Colon Cancer Apoptosis: AMPK/mTOR Pathway Modulation Explored Through Experimental and Computational Approaches12
The Causal Effects of Cholelithiasis on Acute Pancreatitis and Pancreatic Cancer: A Large Sample Size Mendelian Randomization Analysis12
USP31 Activates the Wnt/β-catenin Signaling Pathway and Promotes Gastric Cancer Cell Proliferation, Invasion and Migration12
Bioinformatics Analysis of Key Genes Associated with Resistance to the Combination of Bevacizumab and Pemetrexed Chemotherapy in Non-small Cell Lung Cancer12
Screening of Candidate Inflammatory Markers of Epithelial Cells in Hepatocellular Carcinoma based on Integration Analysis of TCGA/ICGC Databases and Single-cell Sequencing11
Bourgeoning Cancer Targets11
Predictive Modelling of Overall Survival in Adult Patients with Primary Diffuse Large B-cell Lymphoma of the Breast Using the Surveillance, Epidemiology, and End Results (SEER) Database11
Survival Benefits of Ganoderma Lucidum in Early-stage Triple-negative Breast Cancer: A Real World Study11
Integrated Single-cell and Bulk RNA Sequencing Analysis Cross Talk between Ferroptosis-related Genes and Prognosis in Oral Cavity Squamous Cell Carcinoma11
Mechanisms of Anti-PD Therapy Resistance in Digestive System Neoplasms11
Prospective Challenges for Patenting and Clinical Trials of Anticancer Compounds from Natural Products: Coherent Review10
Meet the Editorial Board Member10
Patent Selections10
The m 6 A Reader IGF2BP2 Promotes Oral Squamous Cell Carcinoma Progression by Maintaining UCA1 Stability10
Intracholecystic Papillary-tubular Neoplasm (ICPN) of the Gallbladder: A Case Report Focusing on an Unexpected Pathological Finding10
lncRNA H22954 Inhibits Angiogenesis in Acute Myeloid Leukemia through a PDGFA-dependent Mechanism10
Natural STAT3 Inhibitors for Cancer Treatment: A Comprehensive Literature Review9
Targeting the Key Signaling Pathways in Breast Cancer: From Molecular Mechanism to Therapeutic Interventions9
Metallodrugs as Anticancer Chemotherapeutics and Diagnostic Agents: A Critical Patent Review (2010-2020)9
Acknowledgement to Reviewers9
Circular RNA NF1-419 Inhibits Proliferation and Induces Apoptosis by Regulating Lipid Metabolism in Astroglioma Cells9
Ubiquitination-related Gene UBTD1 Mediates Poor Prognosis of Colorectal Cancer and Affects Colorectal Cancer Cell Proliferation and Ferroptosis9
Puerarin: An Anticancer and Anti-Inflammatory Agent9
Preface8
SSPH I, A Novel Anti-cancer Saponin, Inhibits EMT and Invasion and Migration of NSCLC by Suppressing MAPK/ERK1/2 and PI3K/AKT/ mTOR Signaling Pathways8
Construction and Identification of a Human Colorectal Adenoma Epithelial Cell Line by SV40 Large T-antigen Transfection8
Application of Nano Drug Delivery System (NDDS) in Cancer Therapy: A Perspective8
Fatty Acid Synthase (FASN): A Patent Review Since 2016-Present7
Aucubin Inhibits Liver Cancer via HMGB1-mediated Inactivation of the PI3K/AKT/mTOR Signaling Pathway7
Patent Selections7
Targeted Regulation of Osteoblasts and Osteoclasts in Osteosarcoma Patients by CSF3R Receptor Inhibition of Osteolysis Caused by Tumor Inflammation Based on Transcriptional Spectrum Analysis and Drug 7
The FJQR Has Synergistic Effect with Fluoropyrimidine in the Maintenance Treatment for HER-2 Negative Gastric Cancer7
Adverse Effects of Gefitinib on Skin and Colon in a Lung Cancer Mouse Model7
Investigating the Therapeutic Potential and Molecular Mechanisms ofDaphnetin: A Comprehensive Review7
The Synergistic Effect of Ruthenium Complex Δ-Ru1 and Doxorubicin in a Mouse Breast Cancer Model7
Prognostic and Therapeutic Values of Autophagy-related Genes in Triple-negative Breast Cancer7
Exploring the Anticancer Potentials of Polyphenols: A Comprehensive Review of Patents in the Last Five Years7
Advances in the Treatment of Chronic Myeloid Leukemia7
Patent Selections6
UBE2L3 Suppresses Oxidative Stress-regulated Necroptosis to Accelerate Osteosarcoma Progression6
A Synergistic Combination of Oleanolic Acid and Apatinib to Enhance Antitumor Effect on Liver Cancer Cells and Protect against Hepatic Injury6
Development of a Novel Lipid Metabolism-related Gene Prognostic Signature for Patients with Colorectal Cancer6
pH-responsive Sulfated Hyaluronic Acid Nanoparticles Targeting Tumor Cells and CAFs for the Treatment of Breast Cancer6
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